This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Wiskott-Aldrich syndrome
D3_WISKOTTALDRICH
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
10 |
4. Check minimum number of eventsNone |
10 |
5. Include endpointsNone |
10 |
6. Filter based on genotype QC (FinnGen only) |
9 |
Control definitions (FinnGen only)
- Control exclude
- D3_IMMUNEMECHANISM
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D82
- Name in latin
- Syndroma Wiskott-Aldrich
Similar endpoints
↥List of similar endpoints to
Wiskott-Aldrich syndrome
based on the number of shared cases.
Similar with more cases:
- Immunodeficiency associated with other major defects
- Immunodeficiencies
- Certain disorders involving the immune mechanism
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Gastrointestinal diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 85 | 36 | 49 |
| Only index persons | 71 | 33 | 38 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | - | 56.89 | 38.62 |
| Only index persons | 46.00 | 56.01 | 37.31 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 9 | - | 5 |
| Unadjusted period prevalence (%) | 0.00 | - | 0.00 |
| Median age at first event (years) | 41.34 | - | 35.85 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
10
54
+∞
2.32
6.6
4.6
12.40
7.68
mm/h
—
10
47
10
83
+∞
0.45
17.5
10.8
33.93
22.28
mg/l
—
10
68
0
12
0.00
0.22
0.0
1.7
—
0.76
—
0
5
0
12
0.00
0.22
0.0
1.7
—
9.24
—
0
5
10
88
+∞
0.22
18.4
13.4
85.10
74.51
umol/l
—
10
88
0
5
0.00
0.00
0.0
3.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
9.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
1.23
—
0
7
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_WISKOTTALDRICH and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have D3_WISKOTTALDRICH.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: D3_WISKOTTALDRICH – Wiskott-Aldrich syndrome
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data