Laboratory evidence of human immunodeficiency virus [HIV]

R18_LABOR_EVIDE_HUMAN_IMMUNODEFICIENCY_VIRUS_HIV

No definition available.

Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — R75 Cause of death: ICD-10 — R75 2 out of 7 registries used, show all original rules.	9
4. Check minimum number of events None	9
5. Include endpoints None	9
6. Filter based on genotype QC (FinnGen only)	9

Control definitions (FinnGen only)

Control exclude: R18_ABNORMAL_FINDI_EXAMI_BLOOD_WO_DIAGNOSIS

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: R7
Name in latin: Evidentia laboratorialis agentis viralis HIV

NAME	R18_LABOR_EVIDE_HUMAN_IMMUNODEFICIENCY_VIRUS_HIV
CONTROL_EXCLUDE	R18_ABNORMAL_FINDI_EXAMI_BLOOD_WO_DIAGNOSIS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	R75
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	R75
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Laboratory evidence of human immunodeficiency virus [HIV] based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

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FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	72	38	33
Only index persons	61	34	27
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	46.67	46.41	46.95
Only index persons	46.65	46.41	46.95

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	9	7	-
Unadjusted period prevalence (%)	0.00	0.00	-
Median age at first event (years)	49.74	47.31	-

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

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CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

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N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

+∞

0.46

5.1

4.9

1.41

1.43

mmol/l

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

+∞

0.46

5.2

4.7

4.23

4.56

mmol/l

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

0.00

0.46

0.0

2.8

—

39.39

—

(3004588) Protein electrophoresis panel - Serum or Plasma

0.00

0.23

0.0

1.3

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

+∞

0.22

5.9

5.5

2.42

2.67

mmol/l

—

(3002256) Pathology report gross observation

0.00

0.22

0.0

1.0

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

0.00

0.0

2.6

—

0.05

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

37.74

—

(40768793) Breast Pathology biopsy report

0.00

0.0

1.4

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.0

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

0.00

—

(3003327) Ova and parasites identified in Stool by Light microscopy

0.00

0.0

1.0

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

0.0

1.4

—

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

3.20

—

(36660697) Celiac disease serology panel - Serum

0.00

0.0

1.2

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

11.48

—

(3008898) HLA-B27 [Presence]

0.00

0.0

1.1

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

0.00

0.0

2.6

—

0.91

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

0.00

0.0

2.4

—

2.31

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

0.00

0.0

2.8

—

137.25

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

0.0

2.5

—

52.91

—

(40761535) Cells panel - Urine sediment

0.00

0.0

1.2

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

0.00

0.0

2.9

—

25.41

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

+∞

0.00

27.1

19.7

115.89

69.43

umol/l

—

(3020891) Body temperature

0.00

0.0

3.0

—

(4035726)

0.00

0.0

1.3

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3008152) Bicarbonate [Moles/volume] in Arterial blood

0.00

0.0

9.0

—

24.77

—

(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum

0.00

0.0

1.3

—

Mortality – FinRegistry

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Association

Association between endpoint R18_LABOR_EVIDE_HUMAN_IMMUNODEFICIENCY_VIRUS_HIV and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have R18_LABOR_EVIDE_HUMAN_IMMUNODEFICIENCY_VIRUS_HIV.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

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Index endpoint: R18_LABOR_EVIDE_HUMAN_IMMUNODEFICIENCY_VIRUS_HIV – Laboratory evidence of human immunodeficiency virus [HIV]

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Laboratory evidence of human immunodeficiency virus [HIV]

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints