retinopathy: Any disease or disorder of the retina.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1243 |
4. Check minimum number of eventsNone |
1243 |
5. Include endpointsNone |
1243 |
6. Filter based on genotype QC (FinnGen only) |
1243 |
Control definitions (FinnGen only)
- Control exclude
- H7_CHOROIDRETINA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other specified and unspecified retinal disorders
based on the number of shared cases.
Similar with more cases:
- Other retinal disorders
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8708 | 4643 | 4018 |
| Only index persons | 8147 | 4406 | 3741 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.13 | 0.11 |
| Only index persons | 0.15 | 0.16 | 0.14 |
| Median age at first event (years) | |||
| Whole population | 63.59 | 66.40 | 60.51 |
| Only index persons | 63.65 | 66.36 | 60.46 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1243 | 671 | 572 |
| Unadjusted period prevalence (%) | 0.24 | 0.23 | 0.25 |
| Median age at first event (years) | 63.42 | 63.23 | 63.64 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1077
- Matched controls
- 10769
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H35.9
ICD-10 Finland
Retinal disorder, unspecified
+∞
323.0
508
*
H35.8
ICD-10 Finland
Other specified retinal disorders
10184.5
323.0
544
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
25.7
286.2
419
260
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
808.3
264.7
250
*
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
1425.8
241.1
226
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
22.7
198.6
298
178
XCW99
NOMESCO Finland
Other investigative procedure of eye
12.8
190.8
372
425
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
426.4
184.7
180
5
XCK10
NOMESCO Finland
Photography of fundus of eye
9.5
137.4
311
440
XCD20
NOMESCO Finland
Photoangiography of eye
261.2
136.4
137
6
CKC12
NOMESCO Finland
Photocoagulation of retina
143.6
131.6
138
11
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
187.2
113.8
117
7
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
49.2
107.2
130
30
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
325.1
89.2
89
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
5.1
89.0
333
873
Z96.1
ICD-10 Finland
Presence of intraocular lens
5.9
88.7
281
607
WX140
NOMESCO Finland
Parabulbar anesthesy
20.2
84.4
129
72
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
83.4
79
*
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
+∞
80.2
76
*
H34.8
ICD-10 Finland
Other retinal vascular occlusions
815.1
78.4
76
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
53.9
67.3
80
16
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
+∞
64.2
61
*
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
621.5
60.3
59
*
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
+∞
57.8
55
*
H33.0
ICD-10 Finland
Retinal detachment with retinal break
576.8
56.1
55
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
11.6
52.4
100
94
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
76.3
51.6
58
8
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.8
48.6
436
2122
XCK00
NOMESCO Finland
Perimetry
5.5
45.8
145
296
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
45.1
43
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.6
44.8
465
2430
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
455.7
44.6
44
*
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
74.6
44.4
50
7
37798
ICD-8 Finland
Other diseases of retina and optic nerve, Morbi retinae alii sive NUD
+∞
44.1
42
*
H35.36
ICD-10 Finland
Macular cyst
+∞
44.1
42
*
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
156.4
43.1
45
*
H25.1
ICD-10 Finland
Senile nuclear cataract
2.7
42.4
368
1723
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
+∞
40.9
39
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
145.5
40.0
42
*
H33.3
ICD-10 Finland
Retinal breaks without detachment
207.5
39.1
40
*
ZXA10
NOMESCO Finland
Bilateral
2.8
37.4
283
1200
H43.1
ICD-10 Finland
Vitreous haemorrhage
16.6
37.3
60
38
CKD40
NOMESCO Finland
Endophotocoagulation of retina
196.7
37.0
38
*
H35.37
ICD-10 Finland
Macular holes
347.7
34.1
34
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
4.2
33.6
137
361
H26.4
ICD-10 Finland
After-cataract
3.9
33.5
151
436
XCH00
NOMESCO Finland
Eye pressure measurement
7.1
32.8
83
126
H35.6
ICD-10 Finland
Retinal haemorrhage
326.3
32.0
32
*
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
67.9
29.1
33
5
S01ED51
ATC
timolol, combinations; ophthalmic
4.0
28.5
122
335
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
+∞
28.2
27
*
S01BC03
ATC
diclofenac; ophthalmic
8.9
27.8
60
71
H3601, E113
ICD-10 Finland
NA
+∞
27.2
26
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.1
26.9
483
3055
H53.1
ICD-10 Finland
Subjective visual disturbances
4.3
26.1
102
257
ZXA00
NOMESCO Finland
Right side
2.1
24.3
345
1960
S01BC05
ATC
ketorolac; ophthalmic
5.1
24.1
79
166
H3600, E113
ICD-10 Finland
NA
+∞
24.0
23
*
H36.01
ICD-10 Finland
Diabetic maculopathy
245.2
23.7
24
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
5.3
23.0
72
144
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
18.9
21.8
33
18
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
224.3
21.7
22
*
H35.4
ICD-10 Finland
Peripheral retinal degeneration
117.4
21.6
23
*
ZXA05
NOMESCO Finland
Left side
2.1
21.3
315
1800
ZX198
NOMESCO Finland
Other local administration
35.0
18.9
24
7
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.9
18.4
118
436
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
+∞
16.7
16
*
CS494
NOMESCO Finland
Other visual field testing
5.9
16.5
46
81
S01ED01
ATC
timolol; ophthalmic
4.3
16.0
60
146
H36.00
ICD-10 Finland
Diabetic background retinopathy
33.9
15.8
20
6
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
162.3
15.5
16
*
H20.1
ICD-10 Finland
Chronic iridocyclitis
10.3
15.5
30
30
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
29.1
15.2
20
7
H40.0
ICD-10 Finland
Glaucoma suspect
2.8
15.1
100
379
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.1
14.8
84
287
S01EC01
ATC
acetazolamide; systemic
5.6
14.6
42
77
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
14.6
14
*
3628X
ICD-9 Finland
Other retinal disorders[MORBUS RETINAE ALIA DEFINITA]
+∞
14.6
14
*
S01EE01
ATC
latanoprost; ophthalmic
3.1
14.6
83
284
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
3.6
14.5
67
197
CKC15
NOMESCO Finland
Panretinal photocoagulation
152.0
14.5
15
*
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
4.4
14.2
52
124
114
Kela drug reimbursment
Glaucoma
2.5
13.7
111
470
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
5.3
13.6
41
80
CKC20
NOMESCO Finland
Cryopexy of undetached retina
+∞
13.6
13
*
H34.2
ICD-10 Finland
Other retinal artery occlusions
141.7
13.5
14
*
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
5.5
13.1
38
71
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
28.7
13.0
17
6
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
8.2
12.9
28
35
H26.2
ICD-10 Finland
Complicated cataract
9.8
12.8
25
26
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
+∞
12.5
12
*
H3601, E103
ICD-10 Finland
NA
+∞
12.5
12
*
H30.2
ICD-10 Finland
Posterior cyclitis
+∞
12.5
12
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
7.0
12.4
30
44
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
8.1
12.4
27
34
L04AA06
ATC
mycophenolic acid; systemic
6.5
12.2
31
49
H53.9
ICD-10 Finland
Visual disturbance, unspecified
4.1
12.2
47
119
127
Kela drug reimbursment
Transplant complication
7.1
12.1
29
42
H33.5
ICD-10 Finland
Other retinal detachments
18.3
12.1
18
10
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
11.9
456
3396
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
30.4
11.7
15
5
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
30.4
11.7
15
5
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
65.7
11.6
13
*
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
4.9
11.5
37
78
H3603, E103
ICD-10 Finland
NA
+∞
11.5
11
*
H3603, E113
ICD-10 Finland
NA
+∞
11.5
11
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.1
11.4
137
702
A12AA04
ATC
calcium carbonate; oral
7.1
11.4
27
39
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.2
11.3
34
67
WX002
NOMESCO Finland
Sedation and analgesia
1.8
11.2
207
1248
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
11.3
11.1
20
18
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
28.3
10.7
14
5
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.6
10.7
75
296
N02BE01
ATC
paracetamol; systemic, rectal
1.7
10.5
893
7970
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
10.5
300
2050
A10AA02
ATC
NA
4.8
10.5
34
73
CKD15
NOMESCO Finland
Injection of vitreous substitute
111.1
10.4
11
*
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
+∞
10.4
10
*
1LA05
NOMESCO Finland
NA
+∞
10.4
10
*
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
11.4
10.1
18
16
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
4.9
9.8
31
65
S01EA03
ATC
apraclonidine; ophthalmic
8.8
9.8
20
23
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
9.6
9.8
19
20
A10AA01
ATC
NA
6.1
9.6
25
42
XCW10
NOMESCO Finland
Assessment of vision
15.2
9.5
15
10
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.3
9.5
86
389
H26.02
ICD-10 Finland
Presenil cataract
4.2
9.4
34
82
H30.8
ICD-10 Finland
Other chorioretinal inflammations
+∞
9.4
9
*
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
+∞
9.4
9
*
H34.1
ICD-10 Finland
Central retinal artery occlusion
+∞
9.4
9
*
H3600, E103
ICD-10 Finland
NA
+∞
9.4
9
*
137
Kela drug reimbursment
Uraemia requiring dialysis
12.5
9.4
16
13
F05
ICPC
Visual disturbance other
4.3
9.3
33
78
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
4.3
9.3
33
78
L04AX01
ATC
azathioprine; systemic
2.9
9.3
54
190
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.5
9.2
31
70
H02AB06
ATC
prednisolone; systemic
1.5
9.2
471
3678
Z94.0
ICD-10 Finland
Kidney transplant status
7.5
8.9
20
27
S01EC04
ATC
brinzolamide; ophthalmic
3.0
8.9
51
177
T89
ICPC
Diabetes insulin dependent
3.7
8.9
37
102
Z49.2
ICD-10 Finland
Other dialysis
12.7
8.9
15
12
CA1ME
NOMESCO Finland
Ultrasound oculometry
12.7
8.9
15
12
A98
ICPC
Health maint/preventive medicine
2.0
8.9
997
9305
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.5
8.7
39
114
H25.0
ICD-10 Finland
Senile incipient cataract
2.5
8.6
65
267
B01AC04
ATC
clopidogrel; oral
1.8
8.6
162
979
B05DA
ATC
Isotonic solutions
12.9
8.4
14
11
CKD50
NOMESCO Finland
Endodiathermy of retina
+∞
8.3
8
*
CKD20
NOMESCO Finland
Removal of vitreous body substitute
+∞
8.3
8
*
TCK00
NOMESCO Finland
Photosensitisation of choroid and retina
+∞
8.3
8
*
H30.1
ICD-10 Finland
Disseminated chorioretinal inflammation
+∞
8.3
8
*
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.8
8.3
53
198
H04.10
ICD-10 Finland
Dry eye syndrome
2.1
8.2
96
488
ZX120
NOMESCO Finland
Intravenous
2.1
8.2
97
494
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
4.9
8.1
25
52
A10AE04
ATC
insulin glargine; parenteral
2.1
8.1
88
434
S01EE03
ATC
bimatoprost; ophthalmic
3.8
8.0
32
86
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
8.0
261
1828
H53.4
ICD-10 Finland
Visual field defects
4.1
7.9
29
72
C08CA01
ATC
amlodipine; oral
1.5
7.8
364
2760
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.2
7.8
81
389
S01EE05
ATC
tafluprost; ophthalmic
2.9
7.8
45
158
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
10.9
7.8
14
13
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
15.1
7.7
12
8
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
45.3
7.7
9
*
H44.2
ICD-10 Finland
Degenerative myopia
45.3
7.7
9
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
7.7
121
688
A10AE05
ATC
insulin detemir; parenteral
2.5
7.7
57
234
H25.8
ICD-10 Finland
Other senile cataract
1.9
7.6
112
620
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
10.1
7.5
14
14
A11CC03
ATC
alfacalcidol; systemic
4.0
7.4
28
72
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
10.9
7.3
13
12
H33.4
ICD-10 Finland
Traction detachment of retina
+∞
7.3
7
*
H31.8
ICD-10 Finland
Other specified disorders of choroid
+∞
7.3
7
*
H3602, E113
ICD-10 Finland
NA
+∞
7.3
7
*
1LA04
NOMESCO Finland
NA
+∞
7.3
7
*
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
7.3
7
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
9.4
7.3
14
15
WX142
NOMESCO Finland
Sub-tenon anesthesy
15.9
7.2
11
7
D31.2
ICD-10 Finland
Benign neoplasm: Retina
30.2
7.2
9
*
F28
ICPC
Limited function/disability (F)
12.1
7.1
12
10
WX110
NOMESCO Finland
Local anesthesy
1.4
7.1
648
5561
TK800
NOMESCO Finland
Hemodialysis
3.9
7.0
27
71
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
6.9
231
1620
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
6.8
327
2481
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
40.3
6.8
8
*
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
3.4
6.8
30
89
H54.7
ICD-10 Finland
Unspecified visual loss
7.2
6.7
15
21
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
4.0
6.7
25
64
R51.80
ICD-10 Finland
Headache
1.7
6.7
129
781
H04AA01
ATC
glucagon; nasal, parenteral
4.5
6.7
22
50
S01EC03
ATC
dorzolamide; ophthalmic
4.6
6.6
21
46
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
6.2
6.5
16
26
ZX108
NOMESCO Finland
Inhalation
7.4
6.4
14
19
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
7.4
6.4
14
19
SPAT1301
SPAT
No procedures
1.4
6.4
314
2387
N18.8
ICD-10 Finland
Other chronic renal failure
2.9
6.4
37
131
B05DB
ATC
Hypertonic solutions
11.1
6.3
11
10
H34.9
ICD-10 Finland
Retinal vascular occlusion, unspecified
+∞
6.3
6
*
1LA01
NOMESCO Finland
NA
+∞
6.3
6
*
CKC60
NOMESCO Finland
Local buckling of sclera using implant
+∞
6.3
6
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
6.3
6
*
CKA10
NOMESCO Finland
Biopsy of vitreous body
+∞
6.3
6
*
H30.0
ICD-10 Finland
Focal chorioretinal inflammation
+∞
6.3
6
*
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.9
6.2
92
512
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
6.2
204
1425
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.4
6.2
17
32
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
6.1
375
2966
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
6.1
581
4958
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
6.1
175
1183
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.4
6.1
27
81
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
2.6
6.0
40
156
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
807
6044
1.96
27.07
6.2
4.8
6.9
6.7
mmol/l
1.87
758
5663
770
5882
1.81
21.98
11.6
9.0
4.3
4.1
e9/l
0.99
683
5139
697
5210
1.77
21.01
9.8
6.7
1.2
1.2
mmol/l
0.12
613
4405
470
3186
1.76
19.52
2.5
2.1
219.3
255.3
u/l
0.24
444
2997
611
4501
1.70
18.50
6.6
4.7
35.7
35.3
g/l
0.94
561
4182
1132
10034
2.44
18.45
21.3
15.0
22.2
24.9
mg/l
2.33
923
8039
107
432
2.62
17.83
2.0
2.1
40.3
38.9
u/l
0.29
97
384
906
7474
1.78
17.77
5.4
4.1
13.4
12.8
mm/h
0.53
842
6892
61
189
3.34
16.30
9.3
5.5
1434.4
658.3
iu/ml
0.32
14
31
935
7862
1.76
16.24
10.0
7.6
81.5
78.6
u/l
0.72
886
7372
629
4772
1.64
16.23
8.2
6.0
1.2
1.2
mmol/l
0.04
581
4319
44
110
4.11
16.04
2.2
2.0
10640.0
1400.0
titre
—
5
6
1171
10660
2.70
15.89
14.7
10.6
26.6
26.0
u/l
0.37
1135
10265
40
96
4.27
15.38
1.3
1.1
—
—
—
0
0
31
60
5.27
15.38
2.8
2.0
470.2
667.7
e6/l
0.64
24
55
1045
9142
1.90
15.20
5.4
4.7
4.1
2.1
mu/l
0.49
961
8319
1149
10404
2.38
15.16
23.9
17.5
139.5
139.6
mmol/l
0.87
1124
10131
1151
10431
2.40
15.14
24.4
17.6
4.0
4.0
mmol/l
0.01
1125
10145
1059
9321
1.92
14.87
7.2
5.8
40.8
39.7
mmol/mol
2.95
983
8598
30
59
5.19
14.62
2.3
1.8
11.9
13.9
%
0.31
14
23
824
6780
1.64
14.61
5.8
4.6
370.2
2246.0
e6/l
1.28
19
106
22
36
6.20
12.96
23.2
29.1
113.5
130.6
ug/l
0.54
16
30
635
5023
1.54
12.40
4.6
3.8
0.0
0.0
estimate
0.50
100
927
24
45
5.42
12.32
1.8
2.7
656.0
1209.4
u/ml
1.00
24
45
627
4953
1.54
12.27
4.6
3.8
0.0
0.0
estimate
0.00
95
938
629
4974
1.54
12.24
6.0
5.1
0.0
0.0
estimate
0.00
101
949
272
1770
1.69
12.11
3.3
2.8
1.1
1.1
e6/l
0.01
168
1018
669
5372
1.53
12.05
7.7
6.3
11.7
11.6
umol/l
0.05
643
5094
886
7576
1.59
11.96
4.4
3.9
14.8
14.9
pmol/l
0.17
809
6851
950
8261
1.64
11.95
25.7
18.2
13.9
13.7
%
1.12
925
8073
434
3179
1.56
11.86
3.1
3.1
1796.5
1452.0
ng/l
0.86
382
2712
296
1985
1.64
11.69
4.6
4.0
680.6
375.8
ng/l
0.46
228
1608
26
55
4.81
11.69
2.5
1.9
—
—
—
0
0
540
4161
1.53
11.66
2.7
2.2
78.4
78.1
nmol/l
0.08
494
3704
43
133
3.31
11.57
1.2
1.2
4.4
6.8
u/ml
0.50
25
62
1108
10095
1.90
11.24
5.8
4.9
2.6
2.7
mmol/l
5.70
1027
9240
71
297
2.47
11.01
4.3
2.2
95.5
91.6
%
0.79
66
280
30
75
4.07
10.98
3.2
1.9
752.1
769.6
e6/l
0.05
14
34
1187
11108
2.52
10.97
31.4
22.0
6.8
6.7
e9/l
0.21
1160
10779
1187
11109
2.52
10.95
31.5
22.1
133.6
134.7
g/l
1.59
1171
10929
252
1650
1.66
10.85
3.4
2.9
2.1
2.4
e6/l
0.28
147
901
319
2214
1.59
10.85
3.4
2.6
4.6
5.4
e6/l
0.87
275
1945
1186
11101
2.49
10.84
31.4
21.9
243.8
247.8
e9/l
1.30
1161
10803
538
4188
1.50
10.82
4.1
2.7
141.1
135.1
ug/l
0.18
491
3831
66
269
2.54
10.81
2.1
2.3
12.7
11.8
mg/l
0.29
61
250
165
961
1.83
10.75
8.5
3.5
1.5
2.1
mmol/l
1.24
137
763
1186
11106
2.48
10.73
31.4
21.9
4.4
4.5
e12/l
1.10
1157
10780
130
716
1.91
10.08
3.6
2.8
10.2
10.7
g/l
0.71
121
647
768
6477
1.49
10.06
3.9
3.1
53.8
49.6
u/l
0.45
733
6018
192
1194
1.72
9.97
5.5
2.5
1.7
1.8
%
0.51
169
1048
1084
9884
1.76
9.96
5.2
4.4
4.5
4.6
mmol/l
6.01
1005
9105
190
1180
1.72
9.91
5.1
4.3
228.6
252.2
u/l
1.85
177
1106
1078
9818
1.74
9.89
5.1
4.4
1.4
1.5
mmol/l
1.02
994
8988
75
340
2.28
9.74
2.1
1.6
208.0
156.4
titre
—
5
11
547
4339
1.47
9.67
2.1
2.0
90.8
94.7
pmol/l
1.18
279
2205
151
887
1.80
9.54
3.1
2.8
66.7
66.3
g/l
0.19
133
810
141
812
1.83
9.51
3.4
2.8
63.2
64.4
ml/min/173m2
0.13
48
339
424
3207
1.49
9.50
4.5
3.3
34.5
33.5
u/l
0.19
401
3035
22
49
4.55
9.32
2.2
1.4
—
—
—
0
0
22
49
4.55
9.32
2.2
1.4
—
—
—
0
0
386
2875
1.50
9.29
4.1
3.2
0.3
0.4
e6/l
0.61
292
2167
40
136
3.01
9.25
1.2
1.2
2.5
3.7
u/ml
0.27
17
46
39
131
3.04
9.21
1.1
1.1
—
—
—
0
0
158
955
1.75
9.05
2.6
2.4
5.3
7.0
ug/l
0.75
141
827
23
55
4.24
8.94
1.1
1.2
—
—
—
0
0
1041
9455
1.62
8.92
18.5
14.0
77.1
78.9
ml/min/173m2
1.61
870
7782
96
501
1.99
8.71
2.0
1.9
1.5
1.6
g/l
0.33
82
432
1042
9482
1.61
8.68
4.6
3.9
1.3
1.3
mmol/l
0.19
957
8621
355
2630
1.49
8.67
2.6
2.1
3.1
3.0
mg/l
0.14
305
2207
13
8
16.41
8.56
5.3
7.3
—
—
—
0
0
178
1132
1.67
8.45
4.9
2.8
10.3
8.8
umol/l
0.32
151
976
212
1409
1.61
8.45
11.9
5.3
1.1
1.0
mmol/l
0.81
200
1291
65
296
2.26
8.38
1.6
1.6
1.5
22.3
iu/ml
0.45
17
54
93
487
1.98
8.36
8.7
3.8
23.9
24.3
mmol/l
0.60
84
434
457
3580
1.44
8.27
3.5
3.4
2.4
2.4
mmol/l
0.19
400
3095
37
129
2.93
8.22
1.1
1.1
117.5
117.9
%
0.02
32
118
40
147
2.78
8.08
5.6
3.0
158.0
1962.2
u/ml
—
6
15
42
162
2.65
7.75
2.3
1.4
110.7
104.4
u/ml
0.20
11
26
45
181
2.54
7.64
1.4
1.2
—
—
—
0
0
64
303
2.17
7.54
1.4
2.0
—
—
—
0
0
1066
9833
1.59
7.48
5.3
4.7
6.1
5.9
mmol/l
2.47
975
8921
240
1689
1.52
7.37
5.5
3.2
0.8
0.8
mmol/l
0.27
222
1570
205
1395
1.56
7.33
4.1
2.5
21.6
22.6
%
0.49
169
1187
411
3215
1.42
7.30
3.5
2.5
52.8
57.8
u/l
2.84
381
2950
149
941
1.66
7.24
14.5
6.9
11.0
10.0
mmol/l
1.03
143
900
407
3192
1.41
7.08
4.9
3.8
15.0
8.6
mg/mmol
1.04
276
1992
147
933
1.65
7.01
3.1
3.0
231.6
220.3
ng/l
0.14
127
862
42
171
2.51
6.98
1.5
1.2
322.5
258.3
u/ml
0.75
31
103
109
640
1.77
6.90
2.7
2.5
29.1
25.0
au/ml
—
5
27
134
834
1.68
6.88
5.9
3.7
106.2
87.4
ng/l
0.89
119
722
213
1484
1.53
6.83
4.1
2.4
2.3
2.3
g/l
0.47
193
1375
184
1244
1.56
6.75
6.1
7.7
4.9
5.1
kpa
2.03
172
1186
403
3183
1.39
6.64
4.0
3.1
6.9
7.4
mmol/l
2.12
347
2660
292
2184
1.44
6.54
2.6
1.7
1.2
1.2
mg/l
0.18
226
1669
183
1245
1.55
6.53
6.1
7.7
12.6
12.1
kpa
0.54
171
1192
202
1405
1.52
6.51
30.1
25.3
1.3
1.3
inr
0.08
30
175
125
776
1.68
6.48
2.2
1.6
—
—
—
0
0
76
409
1.91
6.36
2.3
2.5
7.5
7.4
g/l
0.07
49
317
76
409
1.91
6.36
2.3
2.5
4.0
3.7
g/l
0.59
47
304
76
409
1.91
6.36
2.3
2.5
—
—
—
0
0
274
2037
1.44
6.32
1.9
1.8
1186.3
1184.1
nmol/l
0.01
217
1503
59
291
2.08
6.30
5.1
2.5
3.5
3.6
g/l
0.17
54
280
182
1247
1.54
6.28
6.1
7.7
0.2
1.2
mmol/l
2.52
139
974
72
383
1.93
6.24
2.4
2.6
3.2
3.1
g/l
0.06
47
308
26
88
3.00
6.13
1.3
1.3
—
—
—
0
0
181
1250
1.52
6.02
2.1
1.8
—
—
—
0
0
111
685
1.68
5.90
7.5
6.9
24.0
24.5
mmol/l
0.72
102
640
293
2230
1.41
5.89
5.2
4.1
1.0
1.0
kg/l
0.03
40
323
91
534
1.76
5.79
2.8
3.4
4.3
4.5
pmol/l
1.04
80
462
673
5840
1.33
5.78
2.8
2.8
—
—
—
0
0
487
4044
1.34
5.61
3.9
3.8
97.4
49.6
ng/l
0.36
365
2891
70
384
1.87
5.56
2.4
2.6
10.4
10.4
g/l
0.02
50
330
14
34
4.15
5.36
3.3
1.9
—
—
—
0
0
150
1024
1.53
5.25
6.9
8.5
120.6
121.1
g/l
0.11
145
987
219
1617
1.43
5.17
4.2
2.4
11.9
12.9
umol/l
1.23
203
1494
140
945
1.54
5.16
3.4
2.4
44.1
38.8
u/l
0.21
125
807
49
245
2.04
5.10
1.1
1.2
1.9
13.4
u/ml
—
5
43
63
345
1.87
5.05
1.4
1.2
0.5
1.2
u/ml
—
6
27
175
1245
1.47
5.02
2.1
1.8
—
—
—
0
0
557
4777
1.30
4.90
5.2
4.0
—
—
—
0
0
236
1782
1.40
4.90
2.3
1.9
—
—
—
0
0
331
2639
1.35
4.90
1.7
1.6
1.3
1.4
mmol/l
2.50
285
2223
319
2537
1.35
4.78
1.6
1.5
23.3
20.6
nmol/l
1.44
266
2146
10
20
5.03
4.78
1.2
1.1
—
—
—
0
0
338
2712
1.34
4.77
5.2
4.1
0.0
0.0
estimate
0.88
96
915
13
33
3.97
4.72
1.5
1.1
1417.4
1684.6
miu/ml
0.29
13
33
59
325
1.86
4.67
1.4
1.2
—
—
—
0
0
101
649
1.61
4.62
5.3
3.0
128.4
127.7
g/l
0.12
95
635
329
2655
1.33
4.42
3.7
2.7
6331.0
6500.4
umol/l
0.02
292
2295
453
3827
1.29
4.32
5.0
4.0
—
—
—
0
0
157
1133
1.44
4.18
2.1
2.3
166.0
128.9
ug/g
0.40
120
908
11
27
4.10
4.16
2.3
1.6
—
—
—
0
0
969
9034
1.33
4.14
23.5
16.1
39.5
39.6
%
0.24
675
6250
259
2038
1.34
4.11
1.4
1.2
1.8
1.7
u/ml
0.06
70
532
257
2022
1.34
4.08
2.9
3.0
2.5
2.5
mmol/l
0.19
224
1774
208
1596
1.36
3.88
1.2
1.3
15.1
12.5
u/ml
0.19
73
588
24
101
2.40
3.83
1.2
1.2
61.7
52.4
u/l
0.43
15
77
308
2508
1.30
3.82
3.2
2.4
—
—
—
0
0
215
1665
1.35
3.78
1.3
1.3
47.9
35.7
iu/ml
0.44
69
518
7
8
8.79
3.77
10.3
5.5
0.5
0.3
umol/l
—
7
8
174
1307
1.39
3.70
9.3
7.3
—
—
—
0
0
60
358
1.71
3.69
2.7
2.8
0.9
1.3
g/l
0.32
51
313
136
987
1.42
3.53
2.8
2.2
0.2
0.2
g/l
0.17
128
921
7
10
7.03
3.36
1.0
1.3
—
—
—
0
0
22
95
2.34
3.35
2.2
2.3
—
—
—
0
0
8
14
5.74
3.34
1.0
1.1
—
—
—
0
0
14
48
2.94
3.30
1.3
1.2
—
—
—
0
0
272
2225
1.28
3.21
1.8
1.7
26786197.5
27930331.0
pmol/l
0.01
224
1826
8
15
5.36
3.19
1.3
3.3
—
—
—
0
0
45
260
1.76
3.14
1.8
1.6
—
—
—
0
0
45
260
1.76
3.14
2.5
1.3
426.0
485.0
mg/l
0.86
39
243
20
86
2.35
3.09
1.2
1.2
—
—
u/ml
—
0
0
42
240
1.78
3.05
2.9
2.3
109.1
88.3
ug/min
0.17
27
149
54
333
1.65
2.99
2.7
2.6
36.2
37.6
g/l
0.90
46
290
52
318
1.66
2.98
2.8
2.7
0.0
0.0
g/l
0.11
47
292
396
3412
1.24
2.97
5.0
4.9
2.5
2.6
ug/l
0.09
360
3049
97
685
1.45
2.95
1.8
1.6
—
—
—
0
0
50
304
1.67
2.93
1.4
1.5
219.9
285.0
ug/g
1.57
27
173
124
918
1.39
2.90
2.3
2.1
398.5
373.6
nmol/l
0.84
112
836
24
115
2.11
2.89
1.2
1.3
—
—
—
0
0
14
52
2.71
2.89
1.1
2.0
—
—
—
0
0
30
157
1.93
2.86
1.2
1.3
—
—
—
0
0
49
300
1.66
2.81
2.9
2.7
0.0
0.0
g/l
0.00
44
277
67
443
1.54
2.80
2.5
2.0
2.0
1.7
ug/l
0.18
59
392
49
303
1.64
2.71
2.9
2.7
0.0
0.0
g/l
0.00
44
278
8
20
4.02
2.57
2.6
1.3
—
—
—
0
0
48
301
1.62
2.53
1.5
1.4
28.6
30.1
iu/l
0.11
40
247
145
1128
1.32
2.49
3.3
4.3
7.9
15.9
ug/l
0.86
115
939
320
2742
1.22
2.48
4.3
4.2
22.0
21.3
%
0.37
148
1302
15
63
2.40
2.46
1.5
1.1
—
—
—
0
0
17
76
2.25
2.44
3.1
2.2
647.3
602.1
ml
0.20
11
52
39
234
1.69
2.44
1.2
1.1
—
—
—
0
0
39
235
1.68
2.41
1.3
1.3
—
—
—
0
0
38
228
1.69
2.38
2.7
1.5
67.9
754.8
e6/l
0.79
32
183
38
228
1.69
2.38
2.6
1.4
7.3
27.0
e6/l
0.73
31
176
11
40
2.77
2.37
1.0
1.3
—
—
—
0
0
26
139
1.89
2.37
1.7
1.7
—
—
—
0
0
183
1479
1.28
2.37
1.5
1.5
—
—
—
0
0
43
268
1.63
2.34
1.3
1.3
—
—
—
0
0
15
65
2.32
2.32
1.4
1.1
1.0
1.1
u/l
—
6
38
38
233
1.65
2.22
2.6
1.2
3.8
3.8
mmol/l
0.14
33
218
21
107
1.98
2.21
3.5
1.7
—
—
—
0
0
12
48
2.51
2.19
1.4
1.3
—
—
—
0
0
15
67
2.25
2.18
1.2
1.2
—
—
—
0
0
36
219
1.66
2.17
1.6
1.4
7.5
8.9
u/l
0.35
29
170
6
14
4.30
2.15
1.2
1.4
—
—
—
0
0
7
19
3.70
2.15
2.9
2.9
—
—
—
0
0
11
43
2.57
2.10
1.2
1.0
—
—
—
0
0
8
25
3.21
2.09
1.3
1.2
—
—
—
0
0
78
568
1.40
2.07
6.1
10.4
23.6
24.5
mmol/l
1.70
70
531
46
302
1.54
2.05
1.8
1.7
—
—
—
0
0
37
231
1.62
2.04
1.3
1.4
—
—
—
0
0
37
231
1.62
2.04
1.3
1.4
—
—
—
0
0
56
385
1.48
2.02
2.8
2.8
—
—
—
0
0
14
63
2.24
2.01
1.5
1.6
4.3
8.2
u/l
—
6
34
5
11
4.56
1.94
2.2
1.9
—
—
—
0
0
22
121
1.83
1.89
3.5
1.6
—
—
—
0
0
14
65
2.17
1.88
2.1
2.3
—
—
—
0
0
9
34
2.66
1.86
1.1
1.1
—
—
—
0
0
37
238
1.57
1.83
1.3
1.3
327.8
230.2
miu/ml
0.56
15
110
61
437
1.42
1.81
7.3
5.3
1.6
1.6
%
0.17
54
410
7
23
3.05
1.80
1.1
1.3
—
—
—
0
0
59
422
1.42
1.77
2.4
3.2
1656.3
3422.3
u/ml
0.30
48
361
22
125
1.77
1.72
1.2
1.1
—
—
—
0
0
15
75
2.01
1.70
1.5
1.3
—
—
—
0
0
27
165
1.65
1.65
1.1
1.1
—
—
—
0
0
5
14
3.58
1.61
1.6
1.3
166.8
89.1
ng/l
—
5
14
5
14
3.58
1.61
4.8
1.4
—
—
—
0
0
10
43
2.34
1.60
3.7
4.2
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
8
32
2.51
1.60
1.1
2.1
158.4
166.4
%
—
8
32
8
32
2.51
1.60
1.1
1.1
—
—
—
0
0
82
631
1.32
1.59
1.5
1.5
—
—
—
0
0
6
20
3.01
1.58
1.7
1.0
—
—
—
0
0
16
85
1.89
1.55
2.9
2.5
6.0
7.4
umol/l
—
10
55
60
442
1.38
1.55
1.1
1.0
—
—
—
0
0
10
44
2.28
1.53
1.1
1.1
520.8
201.5
iu/ml
—
10
44
7
27
2.60
1.51
1.4
1.1
—
—
—
0
0
5
16
3.13
1.44
1.0
1.2
—
—
—
0
0
91
722
1.28
1.43
2.4
2.1
12.6
12.7
nmol/l
0.01
82
639
42
296
1.43
1.41
1.7
1.7
—
—
—
0
0
23
142
1.63
1.39
1.6
2.4
4.4
31.3
u/ml
0.49
23
137
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
12
60
2.01
1.38
1.3
1.2
—
—
—
0
0
105
854
1.25
1.36
4.2
3.8
1.2
1.2
mmol/l
0.74
90
743
12
61
1.98
1.33
1.3
1.2
—
—
—
0
0
18
106
1.71
1.30
1.0
1.3
203.7
317.5
pmol/l
1.09
11
85
5
18
2.78
1.28
3.8
2.2
12.4
17.8
umol/l
—
5
18
42
305
1.39
1.22
3.0
1.8
—
—
—
0
0
51
384
1.34
1.20
2.9
1.9
—
—
—
0
0
13
71
1.84
1.19
1.0
1.0
797.7
622.8
ng/l
—
6
38
13
71
1.84
1.19
1.0
1.0
60.1
40.0
ng/l
—
7
39
13
71
1.84
1.19
1.0
1.0
440.4
267.8
ng/l
—
8
40
14
79
1.78
1.17
2.4
1.8
—
—
—
0
0
37
266
1.40
1.15
4.7
2.8
23.3
24.8
mmol/l
1.19
31
230
17
103
1.66
1.13
1.5
1.6
—
—
—
0
0
7
30
2.34
1.12
1.4
1.2
—
—
—
0
0
11
58
1.90
1.12
1.3
1.1
—
—
—
0
0
19
119
1.61
1.12
2.5
3.7
—
—
—
0
0
76
612
1.26
1.11
1.2
1.2
150.6
133.3
iu/ml
0.12
20
238
7
31
2.26
1.10
1.6
1.2
—
—
—
0
0
17
104
1.64
1.09
1.2
1.1
—
—
—
0
0
5
21
2.39
1.09
1.0
1.0
—
—
—
0
0
14
82
1.72
1.05
1.0
1.0
—
—
—
0
0
32
229
1.41
1.04
1.5
1.8
7.6
4.9
iu/l
0.42
12
78
41
307
1.35
1.03
1.2
1.1
—
—
—
0
0
13
75
1.74
1.03
1.2
1.1
—
61.9
—
0
8
83
684
1.23
1.01
4.1
3.7
5.0
5.2
kpa
1.67
77
636
21
139
1.52
1.00
1.3
1.4
—
—
—
0
0
21
139
1.52
1.00
1.3
1.4
—
—
—
0
0
21
139
1.52
1.00
1.3
1.4
—
—
—
0
0
21
139
1.52
1.00
1.3
1.4
—
—
—
0
0
7
35
2.01
1.00
2.7
3.0
—
—
—
0
0
7
35
2.01
1.00
1.0
2.1
—
—
—
0
0
7
35
2.01
1.00
2.7
3.0
—
—
—
0
0
41
309
1.34
0.99
1.2
1.1
—
—
—
0
0
79
649
1.23
0.99
4.0
3.7
1.6
1.9
mmol/l
0.43
59
488
88
733
1.22
0.97
1.5
1.8
—
—
—
0
0
19
124
1.54
0.97
1.1
1.1
0.2
2.3
u/ml
—
7
54
45
346
1.31
0.96
3.7
3.9
44.7
72.5
mg/l
0.82
38
279
45
347
1.31
0.94
3.7
3.9
31.8
48.8
mg/l
0.88
37
281
23
158
1.46
0.94
1.3
1.6
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
48
374
1.29
0.94
2.6
2.7
0.3
0.4
u/ml
0.70
25
212
6
27
2.23
0.93
1.5
1.1
—
—
—
0
0
219
1977
1.13
0.90
2.8
3.0
0.7
0.8
ug/l
0.63
150
1304
6
29
2.07
0.89
1.3
1.3
—
—
—
0
0
151
1332
1.15
0.87
1.3
1.4
—
—
—
0
0
12
72
1.67
0.85
1.5
1.1
—
—
—
0
0
12
72
1.67
0.85
1.5
1.1
—
—
—
0
0
125
1091
1.16
0.84
3.3
3.5
—
—
—
0
0
12
73
1.65
0.81
1.5
1.1
—
—
—
0
0
12
73
1.65
0.81
1.5
1.1
—
—
—
0
0
12
73
1.65
0.81
1.5
1.1
—
—
—
0
0
15
98
1.54
0.78
1.1
1.3
—
—
—
0
0
12
74
1.63
0.78
1.1
1.2
—
—
—
0
0
21
149
1.42
0.76
1.4
1.5
—
—
—
0
0
26
192
1.36
0.75
3.7
1.4
0.8
0.9
nmol/l
0.25
20
159
9
53
1.70
0.75
8.4
4.6
—
—
—
0
0
12
75
1.61
0.75
1.1
1.2
—
—
—
0
0
7
39
1.80
0.72
1.0
1.0
—
—
—
0
0
27
204
1.33
0.69
1.5
2.3
1062.8
3462.8
u/l
—
7
82
11
69
1.60
0.68
1.8
1.3
9.1
2.5
ug/l
0.47
11
58
33
258
1.29
0.67
1.6
1.6
16804.1
15144.8
e6/l
0.05
27
189
14
96
1.46
0.61
4.4
1.5
—
—
—
0
0
14
96
1.46
0.61
4.4
1.5
—
—
—
0
0
14
96
1.46
0.61
4.4
1.5
—
—
—
0
0
5
30
1.67
0.61
1.8
1.1
—
—
—
0
0
5
30
1.67
0.61
1.2
1.2
117.8
106.0
%
—
5
24
12
80
1.50
0.60
1.4
1.4
10.8
13.4
u/l
0.82
12
75
8
52
1.54
0.59
6.0
1.6
—
—
—
0
0
8
52
1.54
0.59
6.0
1.6
—
—
—
0
0
8
52
1.54
0.59
6.0
1.6
—
—
—
0
0
8
52
1.54
0.59
6.0
1.6
—
—
—
0
0
23
298
0.77
0.58
1.6
1.7
—
—
—
0
0
28
220
1.28
0.57
1.4
1.6
—
—
—
0
0
6
36
1.67
0.56
1.3
1.6
—
—
—
0
0
117
1298
0.89
0.56
4.8
4.4
34.9
32.5
%
1.58
85
865
20
150
1.34
0.56
1.4
1.1
—
—
—
0
0
25
195
1.29
0.54
4.5
3.2
4.3
4.2
e9/l
0.17
25
195
31
249
1.25
0.54
3.6
1.7
—
—
—
0
0
17
125
1.36
0.53
1.7
1.4
24758.8
37718.9
e6/l
—
10
69
9
62
1.45
0.53
4.2
2.0
—
—
—
0
0
123
1114
1.12
0.53
1.8
1.8
1.6
1.5
%
0.31
96
967
31
251
1.24
0.51
1.7
1.8
37.1
38.7
nmol/l
0.21
31
241
6
41
1.47
0.50
7.3
1.8
—
—
—
0
0
6
41
1.47
0.50
7.3
1.8
—
—
—
0
0
7
45
1.56
0.49
1.4
1.3
—
—
—
0
0
29
235
1.24
0.48
1.8
1.4
—
—
—
0
0
16
120
1.34
0.46
15.0
5.7
6.9
7.6
mmol/l
0.60
16
101
25
203
1.24
0.42
5.3
3.3
61.2
57.6
%
0.97
25
203
51
446
1.15
0.40
2.9
1.9
—
—
—
0
0
47
409
1.16
0.39
2.3
1.8
—
—
—
0
0
29
242
1.20
0.39
3.9
1.7
—
—
—
0
0
9
68
1.33
0.37
1.8
1.4
—
—
—
0
0
9
68
1.33
0.37
1.9
1.4
—
—
—
0
0
22
180
1.23
0.36
4.1
1.7
—
—
—
0
0
6
42
1.43
0.35
7.5
1.8
—
—
—
0
0
6
43
1.40
0.35
1.5
1.2
—
75.3
%
—
0
6
54
482
1.13
0.33
1.4
1.3
—
—
—
0
0
14
109
1.29
0.33
2.9
1.7
—
—
—
0
0
30
257
1.17
0.32
1.5
1.5
—
—
—
0
0
21
174
1.21
0.31
2.3
1.6
—
—
—
0
0
72
787
0.91
0.31
2.6
1.9
—
—
—
0
0
7
56
1.25
0.29
1.9
1.4
—
—
—
0
0
7
56
1.25
0.29
1.9
1.4
—
—
—
0
0
65
711
0.91
0.29
2.3
1.8
—
—
—
0
0
16
130
1.23
0.28
2.0
2.4
55.3
26.6
mg/l
—
6
31
33
290
1.14
0.27
1.4
1.3
—
—
—
0
0
27
235
1.15
0.25
2.0
1.4
—
—
—
0
0
28
245
1.15
0.25
1.4
1.4
—
—
—
0
0
15
124
1.21
0.24
1.8
1.5
53.1
62.8
%
—
9
81
5
39
1.28
0.23
2.6
2.0
28.8
16.7
ug/l
—
5
31
15
125
1.20
0.22
1.4
1.6
—
—
—
0
0
5
40
1.25
0.22
1.0
1.1
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
6
50
1.20
0.19
1.0
1.5
—
72.2
—
0
9
6
52
1.15
0.19
2.0
1.5
—
—
—
0
0
16
137
1.17
0.19
2.5
1.6
—
—
—
0
0
11
92
1.20
0.16
1.6
1.9
0.8
2.7
u/field
—
5
35
13
112
1.16
0.14
1.6
1.5
5.5
6.6
mmol/l
1.23
13
105
20
179
1.12
0.14
1.6
1.9
217.5
212.9
pmol/l
0.07
20
168
25
274
0.91
0.14
1.2
1.4
—
—
—
0
0
12
103
1.17
0.13
1.1
1.3
17153.0
105444.3
e6/l
—
7
75
8
100
0.80
0.13
1.4
1.4
—
—
—
0
0
30
279
1.08
0.11
3.2
3.2
0.7
0.8
nmol/l
1.21
24
224
12
135
0.89
0.10
3.0
1.6
—
—
—
0
0
20
216
0.92
0.08
3.3
2.5
14.8
15.6
%
0.36
11
101
5
64
0.78
0.08
3.2
1.5
—
—
—
0
0
6
70
0.86
0.07
1.7
1.8
21.5
19.5
nmol/l
—
6
64
16
174
0.92
0.07
1.4
1.5
—
—
—
0
0
9
84
1.07
0.07
1.4
1.2
—
—
—
0
0
24
254
0.94
0.06
1.1
1.2
—
—
—
0
0
11
100
1.10
0.05
2.2
2.9
13.1
13.2
%
0.29
11
100
35
337
1.04
0.05
1.6
1.8
1.4
3.0
mg/l
2.41
24
242
13
139
0.93
0.03
2.5
1.5
—
—
—
0
0
15
141
1.06
0.03
2.5
1.5
—
—
—
0
0
13
138
0.94
0.02
2.7
1.5
—
—
—
0
0
14
148
0.95
0.02
3.4
1.6
—
—
—
0
0
13
137
0.95
0.01
2.7
1.5
—
—
—
0
0
13
137
0.95
0.01
2.7
1.5
—
—
—
0
0
15
157
0.95
0.01
2.7
1.5
—
—
—
0
0
24
233
1.03
0.01
3.6
3.8
39.1
27.3
mg/l
0.65
17
151
17
174
0.98
0.00
2.5
1.9
1.7
1.6
mmol/l
0.18
17
169
10
101
0.99
0.00
1.4
1.4
105.6
306.4
u/l
—
10
96
11
109
1.01
0.00
2.3
2.6
—
—
—
0
0
13
131
0.99
0.00
1.1
1.0
—
—
—
0
0
14
141
0.99
0.00
2.6
1.5
—
—
—
0
0
12
117
1.03
0.00
1.8
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
8
89
0.90
0.00
1.5
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_RETINANAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINANAS | 0.998 [0.87, 1.15] | 0.977 |
| Birth year | 0.996 [0.99, 1.0] | 0.289 |
During the follow-up period (1.1.1998 — 31.12.2019), 685 out of 3642 females with H7_RETINANAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINANAS | 1.067 [0.91, 1.25] | 0.416 |
| Birth year | 0.988 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 601 out of 3031 males with H7_RETINANAS died.
Mortality risk
Mortality risk for people of age
years, who have H7_RETINANAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.1% | 0.25% |
| 5 | 0.647% | 1.275% |
| 10 | 1.654% | 3.094% |
| 15 | 3.085% | 6.093% |
| 20 | 5.306% | 10.422% |
Relationships between endpoints
↥Index endpoint: H7_RETINANAS – Other specified and unspecified retinal disorders
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data