retinopathy: Any disease or disorder of the retina.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1354 |
4. Check minimum number of eventsNone |
1354 |
5. Include endpointsNone |
1354 |
6. Filter based on genotype QC (FinnGen only) |
1304 |
Control definitions (FinnGen only)
- Control exclude
- H7_CHOROIDRETINA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other specified and unspecified retinal disorders
based on the number of shared cases.
Similar with more cases:
- Other retinal disorders
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8708 | 4643 | 4018 |
| Only index persons | 8147 | 4406 | 3741 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.13 | 0.11 |
| Only index persons | 0.15 | 0.16 | 0.14 |
| Median age at first event (years) | |||
| Whole population | 63.59 | 66.40 | 60.51 |
| Only index persons | 63.65 | 66.36 | 60.46 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1304 | 709 | 595 |
| Unadjusted period prevalence (%) | 0.26 | 0.25 | 0.27 |
| Median age at first event (years) | 64.06 | 63.89 | 64.26 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1354
- Matched controls
- 13540
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
XCD20
NOMESCO Finland
Photoangiography of eye
172.4
310.6
153
10
XCW99
NOMESCO Finland
Other investigative procedure of eye
12.6
307.7
444
505
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
413.6
307.7
317
10
H35.8
ICD-10 Finland
Other specified retinal disorders
+∞
307.7
719
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
20.7
307.7
369
241
CKC12
NOMESCO Finland
Photocoagulation of retina
143.4
307.7
175
14
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
21.0
307.7
530
402
H35.9
ICD-10 Finland
Retinal disorder, unspecified
1898.1
307.7
621
6
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
497.9
290.7
280
7
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
94.3
288.8
151
18
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
39.0
284.1
177
52
XCK10
NOMESCO Finland
Photography of fundus of eye
8.8
237.5
351
520
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
343.0
231.4
228
8
WX140
NOMESCO Finland
Parabulbar anesthesy
17.7
212.5
180
116
Z01.0
ICD-10 Finland
Examination of eyes and vision
5.5
183.0
481
1239
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
65.2
175.8
97
16
Z96.1
ICD-10 Finland
Presence of intraocular lens
5.4
155.3
386
935
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
64.2
131.9
73
12
XCD10
NOMESCO Finland
Electrophysiological examination of eye
13.1
121.5
120
100
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
1242.5
118.6
114
*
H34.8
ICD-10 Finland
Other retinal vascular occlusions
290.7
106.5
107
*
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
101.3
96
*
H43.1
ICD-10 Finland
Vitreous haemorrhage
18.4
92.7
75
43
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
+∞
89.6
85
*
XCK00
NOMESCO Finland
Perimetry
5.6
84.5
174
347
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
382.3
73.4
73
*
H26.4
ICD-10 Finland
After-cataract
4.1
72.7
228
638
H33.0
ICD-10 Finland
Retinal detachment with retinal break
724.7
70.7
69
*
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
34.9
69.3
44
13
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.7
68.6
584
2946
XCH00
NOMESCO Finland
Eye pressure measurement
6.0
67.1
125
226
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
680.4
66.5
65
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
4.2
65.4
191
505
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
+∞
65.1
62
*
H35.36
ICD-10 Finland
Macular cyst
658.4
64.4
63
*
H25.1
ICD-10 Finland
Senile nuclear cataract
2.7
63.7
512
2491
ZXA10
NOMESCO Finland
Bilateral
2.9
60.0
358
1485
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
162.3
59.4
62
*
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
57.7
55
*
S01ED51
ATC
timolol, combinations; ophthalmic
4.0
55.3
174
484
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
190.9
53.3
55
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.4
53.2
572
3134
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
187.3
52.3
54
*
CKD40
NOMESCO Finland
Endophotocoagulation of retina
516.6
50.8
50
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
135.1
49.1
52
*
H33.3
ICD-10 Finland
Retinal breaks without detachment
172.9
48.2
50
*
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
473.5
46.6
46
*
37798
ICD-8 Finland
Other diseases of retina and optic nerve, Morbi retinae alii sive NUD
+∞
45.0
43
*
H35.37
ICD-10 Finland
Macular holes
452.0
44.5
44
*
H53.1
ICD-10 Finland
Subjective visual disturbances
3.7
42.0
143
418
S01BC03
ATC
diclofenac; ophthalmic
6.7
41.6
67
104
H43.8
ICD-10 Finland
Other disorders of vitreous body
3.2
41.5
180
614
H35.6
ICD-10 Finland
Retinal haemorrhage
+∞
40.8
39
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.3
40.4
171
574
H20.1
ICD-10 Finland
Chronic iridocyclitis
14.1
40.0
37
27
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.8
39.3
93
207
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.1
37.6
651
4166
ZXA00
NOMESCO Finland
Right side
2.2
37.2
441
2441
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
13.3
36.7
35
27
XCW10
NOMESCO Finland
Assessment of vision
9.8
36.1
42
44
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
100.4
35.9
39
*
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
95.1
33.9
37
*
H3601, E113,
ICD-10 Finland
+∞
32.4
31
*
S01BC05
ATC
ketorolac; ophthalmic
4.2
31.7
87
217
S01ED01
ATC
timolol; ophthalmic
4.6
31.4
77
176
S01EC01
ATC
acetazolamide; systemic
6.3
31.1
53
87
ZXA05
NOMESCO Finland
Left side
2.1
31.0
398
2245
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
4.5
30.2
75
173
H36.01
ICD-10 Finland
Diabetic maculopathy
84.6
29.9
33
*
H3600, E113,
ICD-10 Finland
+∞
29.3
28
*
H53.9
ICD-10 Finland
Visual disturbance, unspecified
4.3
28.1
74
179
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.5
27.9
206
922
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
265.5
25.8
26
*
H26.2
ICD-10 Finland
Complicated cataract
9.3
25.7
31
34
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
8.8
24.6
31
36
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
7.7
24.3
34
45
H35.4
ICD-10 Finland
Peripheral retinal degeneration
68.7
23.9
27
*
H40.0
ICD-10 Finland
Glaucoma suspect
2.7
23.8
133
518
Z3231
NOMESCO Finland
Registered nurse
1.9
23.6
405
2491
127
Kela drug reimbursment
Transplant complication
6.6
22.3
36
56
CS494
NOMESCO Finland
Other visual field testing
4.4
22.2
57
135
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
6.8
21.7
34
51
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
20.9
20
*
H36.00
ICD-10 Finland
Diabetic background retinopathy
78.1
20.7
23
*
H34.2
ICD-10 Finland
Other retinal artery occlusions
213.1
20.6
21
*
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
3.0
19.2
86
297
Z94.0
ICD-10 Finland
Kidney transplant status
8.2
18.8
25
31
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.6
18.8
45
101
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
28.3
18.8
25
9
S01EE01
ATC
latanoprost; ophthalmic
2.7
18.7
108
427
114
Kela drug reimbursment
Glaucoma
2.4
18.6
143
647
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
192.6
18.6
19
*
S01EC04
ATC
brinzolamide; ophthalmic
3.1
18.1
76
252
CKD15
NOMESCO Finland
Injection of vitreous substitute
+∞
17.7
17
*
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
4.4
17.7
45
106
L04AA06
ATC
mycophenolic acid; systemic
5.0
17.6
38
78
Z2221
NOMESCO Finland
Medical doctor
1.8
17.6
376
2435
A10AB01
ATC
insulin (human); parenteral
4.7
17.6
41
90
CKC20
NOMESCO Finland
Cryopexy of undetached retina
182.3
17.5
18
*
S01EA05
ATC
brimonidine; ophthalmic
3.8
17.0
53
145
H33.5
ICD-10 Finland
Other retinal detachments
26.0
16.9
23
9
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
4.0
16.2
46
118
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
13.1
15.7
27
21
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
15.7
482
3420
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
+∞
15.7
15
*
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
+∞
15.7
15
*
ZXE00
NOMESCO Finland
One hour or less
1.6
15.6
517
3738
A10AA02, ,
ATC
4.4
15.1
38
89
WX002
NOMESCO Finland
Sedation and analgesia
1.8
15.0
268
1639
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.6
14.7
48
136
3628X
ICD-9 Finland
Other retinal disorders[MORBUS RETINAE ALIA DEFINITA]
+∞
14.6
14
*
H30.2
ICD-10 Finland
Posterior cyclitis
+∞
14.6
14
*
A10AE04
ATC
insulin glargine; parenteral
2.2
14.5
127
607
ZX198
NOMESCO Finland
Other local administration
11.5
14.3
26
23
A12AA04
ATC
calcium carbonate; oral
4.7
14.3
33
72
H53.4
ICD-10 Finland
Visual field defects
4.2
14.2
38
93
L04AX01
ATC
azathioprine; systemic
2.9
14.2
66
233
H04AA01
ATC
glucagon; nasal, parenteral
5.9
14.0
25
43
A10AC01
ATC
insulin (human); parenteral
2.4
13.7
97
423
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
6.6
13.7
22
34
CKD20
NOMESCO Finland
Removal of vitreous body substitute
+∞
13.6
13
*
H3601, E103,
ICD-10 Finland
+∞
13.6
13
*
A10AE05
ATC
insulin detemir; parenteral
2.7
13.5
72
273
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
141.4
13.5
14
*
A10AA01, ,
ATC
5.1
13.4
28
56
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
13.4
402
2814
F05
ICPC
Visual disturbance other
3.3
13.4
50
155
S01EA03
ATC
apraclonidine; ophthalmic
10.6
13.3
25
24
A10AB05
ATC
insulin aspart; parenteral
2.4
13.2
96
423
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
12.3
13.1
23
19
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
11.1
13.0
24
22
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
13.0
504
3739
CKC15
NOMESCO Finland
Panretinal photocoagulation
32.4
12.6
16
5
H3600, E103,
ICD-10 Finland
+∞
12.5
12
*
H30.8
ICD-10 Finland
Other chorioretinal inflammations
+∞
12.5
12
*
H3603, E113,
ICD-10 Finland
+∞
12.5
12
*
H3603, E103,
ICD-10 Finland
+∞
12.5
12
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
24.6
12.5
17
7
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
131.2
12.5
13
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.8
12.3
37
99
T89
ICPC
Diabetes insulin dependent
3.3
12.3
46
143
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
37.9
12.2
15
*
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
16.0
12.2
19
12
ZX120
NOMESCO Finland
Intravenous
2.0
12.1
135
706
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
27.0
12.1
16
6
H25.0
ICD-10 Finland
Senile incipient cataract
2.3
12.0
92
415
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
4.4
12.0
30
70
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
11.8
11.8
21
18
L17
ICPC
Foot/toe symptom/complaint
1.6
11.8
371
2614
H26.02
ICD-10 Finland
Presenil cataract
3.5
11.7
40
117
H02AB06
ATC
prednisolone; systemic
1.5
11.6
615
4841
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.5
11.6
39
113
H34.1
ICD-10 Finland
Central retinal artery occlusion
+∞
11.5
11
*
S01EE05
ATC
tafluprost; ophthalmic
2.7
11.3
61
233
N18.8
ICD-10 Finland
Other chronic renal failure
3.3
11.3
42
130
A11CC03
ATC
alfacalcidol; systemic
3.4
11.3
40
120
H52.1
ICD-10 Finland
Myopia
3.1
11.2
46
151
A10AB04
ATC
insulin lispro; parenteral
3.6
11.2
36
101
ZXD20
NOMESCO Finland
Day surgery
1.8
11.2
170
986
A98
ICPC
Health maint/preventive medicine
2.3
11.1
1278
11939
L04AD02
ATC
tacrolimus; systemic
5.8
11.0
20
35
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
11.0
610
4832
H44.2
ICD-10 Finland
Degenerative myopia
43.7
10.9
13
*
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.5
10.9
70
292
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
18.0
10.7
16
9
AA1AD
NOMESCO Finland
CT of head and brain
1.5
10.7
367
2626
A02BC02
ATC
pantoprazole; systemic
1.5
10.5
872
7445
1LA05, ,
NOMESCO Finland
+∞
10.4
10
*
N02BE01
ATC
paracetamol; systemic, rectal
1.7
10.3
1172
10692
S01EE03
ATC
bimatoprost; ophthalmic
3.1
10.2
41
133
B01AC04
ATC
clopidogrel; oral
1.7
10.1
226
1460
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
10.1
10.0
19
19
S01EC03
ATC
dorzolamide; ophthalmic
4.1
10.0
27
67
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
40.4
10.0
12
*
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
55.4
9.7
11
*
S01EC54
ATC
brinzolamide, combinations; ophthalmic
4.3
9.6
24
56
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
9.6
249
1669
R42
ICD-10 Finland
Dizziness and giddiness
1.6
9.5
293
2044
CKA10
NOMESCO Finland
Biopsy of vitreous body
100.7
9.4
10
*
TCK00
NOMESCO Finland
Photosensitisation of choroid and retina
+∞
9.4
9
*
H25.8
ICD-10 Finland
Other senile cataract
1.8
9.3
142
823
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
9.3
282
1956
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
9.3
110
588
Z31.5
ICD-10 Finland
Genetic counselling
2.4
9.3
65
283
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.7
9.2
28
76
L04AD01
ATC
ciclosporin; systemic
3.8
9.1
27
72
S01EE04
ATC
travoprost; ophthalmic
3.3
9.1
34
106
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
9.0
430
3275
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.2
9.0
72
332
C69.30
ICD-10 Finland
Malignant tumor of the chorioidea without histology
24.2
8.9
12
5
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
8.9
94
483
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
8.8
227
1515
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
8.7
137
801
TK800
NOMESCO Finland
Hemodialysis
3.1
8.7
35
114
H54.7
ICD-10 Finland
Unspecified visual loss
7.7
8.7
19
25
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.9
8.6
114
633
L04AX03
ATC
methotrexate; systemic
1.8
8.6
123
700
C08CA01
ATC
amlodipine; oral
1.4
8.6
503
3973
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.8
8.5
41
148
H47.1
ICD-10 Finland
Papilloedema, unspecified
10.1
8.5
16
16
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.1
8.5
76
367
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
8.4
122
697
A10AD01
ATC
insulin (human); parenteral
4.5
8.4
20
45
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
8.4
865
7521
H34.9
ICD-10 Finland
Retinal vascular occlusion, unspecified
+∞
8.3
8
*
H30.1
ICD-10 Finland
Disseminated chorioretinal inflammation
+∞
8.3
8
*
H33.4
ICD-10 Finland
Traction detachment of retina
+∞
8.3
8
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
8.3
8
*
H33.2
ICD-10 Finland
Serous retinal detachment
+∞
8.3
8
*
CKD50
NOMESCO Finland
Endodiathermy of retina
+∞
8.3
8
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
8.3
296
2121
UJF32
NOMESCO Finland
Coloscopy
1.5
8.3
327
2392
137
Kela drug reimbursment
Uraemia requiring dialysis
6.5
8.2
20
31
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.9
8.1
106
586
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
10.1
8.0
15
15
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
8.0
142
861
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
4.5
7.9
19
43
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
13.1
7.9
13
10
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
7.9
153
951
A04
ICPC
Weakness/tiredness general
1.6
7.8
183
1193
B05DA
ATC
Isotonic solutions
7.0
7.8
18
26
H35
ICD-10 Finland
Other retinal disorders
45.2
7.7
9
*
F29
ICPC
Eye symptom/complaint other
1.8
7.7
116
670
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
7.6
433
3384
B05DB
ATC
Hypertonic solutions
8.1
7.6
16
20
CKE60
NOMESCO Finland
Brachytherapy of choroid and retina
25.2
7.6
10
*
CKE65
NOMESCO Finland
Removal of brachytherapeutic plate from eye
25.2
7.6
10
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.2
7.6
65
309
Z49.2
ICD-10 Finland
Other dialysis
7.2
7.5
17
24
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
7.4
207
1404
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
3.8
7.4
22
59
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.8
7.4
22
59
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
7.3
487
3903
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
7.3
7
*
1LA01, ,
NOMESCO Finland
+∞
7.3
7
*
H3602, E113,
ICD-10 Finland
+∞
7.3
7
*
1LA04, ,
NOMESCO Finland
+∞
7.3
7
*
CKC60
NOMESCO Finland
Local buckling of sclera using implant
+∞
7.3
7
*
H31.8
ICD-10 Finland
Other specified disorders of choroid
+∞
7.3
7
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.0
7.3
81
424
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
4.2
7.3
19
46
SFA10
NOMESCO Finland
One-surface restoration
1.4
7.3
635
5317
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
7.2
156
995
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
7.2
782
6769
Z3226
NOMESCO Finland
Physiotherapist
1.5
7.2
229
1599
SPAT1301
SPAT
No procedures
1.4
7.2
383
2955
R05
ICPC
Cough
1.5
7.2
287
2100
N02AX02
ATC
tramadol; systemic, rectal
1.4
7.2
537
4386
D31.2
ICD-10 Finland
Benign neoplasm: Retina
30.2
7.2
9
*
CHC05
NOMESCO Finland
Iridotomy
3.5
7.1
24
70
Z71.8
ICD-10 Finland
Other specified counselling
1.4
7.1
354
2698
WX142
NOMESCO Finland
Sub-tenon anesthesy
10.1
7.0
13
13
L28
ICPC
Limited function/disability (L)
1.5
7.0
226
1583
R05
ICD-10 Finland
Cough
1.5
7.0
247
1764
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
5.9
6.9
18
31
R53
ICD-10 Finland
Malaise and fatigue
1.5
6.9
289
2131
SPAT1263
SPAT
Sampling
1.4
6.8
498
4041
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.2
6.8
55
255
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
9.4
6.8
13
14
G35
ICD-10 Finland
Multiple sclerosis
3.7
6.8
21
58
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
16.8
6.7
10
6
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
6.7
317
2388
J01DB01
ATC
cefalexin; oral
1.4
6.7
1034
9413
R4110
NOMESCO Finland
Physiotherapy
1.4
6.7
338
2576
G03DC03
ATC
lynestrenol; oral
3.2
6.7
25
78
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
6.6
312
2349
C10AA05
ATC
atorvastatin; oral
1.4
6.6
520
4262
CA1ME
NOMESCO Finland
Ultrasound oculometry
6.5
6.6
16
25
N03AX16
ATC
[U] pregabalin
1.4
6.6
283
2094
CKD60
NOMESCO Finland
Anterior vitrectomy
5.9
6.6
17
29
Z2445
NOMESCO Finland
Psychologist
2.3
6.6
47
207
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.6
674
5750
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.7
6.6
130
811
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
12.3
6.6
11
9
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
2.8
6.6
32
117
H20.8
ICD-10 Finland
Other iridocyclitis
8.7
6.6
13
15
J01MA14
ATC
moxifloxacin; systemic
1.7
6.5
112
672
A28
ICPC
Limited function/disability NOS
1.5
6.5
221
1562
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
6.5
765
6655
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.2
6.5
52
241
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
6.4
196
1355
L84
ICD-10 Finland
Corns and callosities
2.3
6.4
46
203
S01BA01
ATC
dexamethasone; ophthalmic
2.3
6.4
46
203
C09CA06
ATC
candesartan; oral
1.4
6.4
283
2109
Z2446
NOMESCO Finland
Social worker
1.9
6.3
83
460
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
5.2
6.3
18
35
H21.0
ICD-10 Finland
Hyphaema
11.1
6.3
11
10
CL2L4
NOMESCO Finland
Wide-field fundus photography for diabetic retinopathy screening
+∞
6.3
6
*
H30.0
ICD-10 Finland
Focal chorioretinal inflammation
+∞
6.3
6
*
H43.2
ICD-10 Finland
Crystalline deposits in vitreous body
26.8
6.2
8
*
V03AE01
ATC
polystyrene sulfonate; oral
3.7
6.2
19
52
T90
ICPC
Diabetes non-insulin dependent
1.4
6.2
282
2110
SFA20
NOMESCO Finland
Two-surface restoration
1.3
6.1
662
5673
M79.6
ICD-10 Finland
Pain in limb
1.3
6.1
503
4144
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.9
6.1
78
430
S01BA04
ATC
prednisolone; ophthalmic
2.7
6.0
30
111
C08CA13
ATC
lercanidipine; oral
1.5
6.0
182
1256
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
878
6554
1.97
29.92
6.3
4.8
6.90
6.69
mmol/l
1.85
827
6149
841
6415
1.82
24.21
11.7
9.0
4.29
4.12
e9/l
0.83
749
5596
762
5665
1.79
23.70
10.1
6.7
1.21
1.21
mmol/l
0.15
677
4812
679
4887
1.78
23.54
6.6
4.7
35.73
35.30
g/l
1.27
628
4547
999
8164
1.85
21.50
5.4
4.1
13.28
12.83
mm/h
0.45
934
7528
120
468
2.72
21.38
1.9
2.0
41.02
38.79
u/l
0.57
108
413
1239
10953
2.54
21.20
21.2
15.0
21.85
25.00
mg/l
3.31
1009
8728
504
3448
1.74
19.90
2.6
2.1
213.86
247.94
u/l
0.24
477
3247
690
5170
1.68
19.23
8.5
6.0
1.21
1.21
mmol/l
0.03
644
4710
45
101
4.57
18.78
1.2
1.1
—
—
—
0
0
68
207
3.41
18.64
9.6
5.6
1262.25
695.48
iu/ml
0.25
16
31
1022
8578
1.78
18.09
10.0
7.6
80.88
78.33
u/l
0.68
973
8054
1280
11642
2.82
17.91
14.8
10.6
26.46
25.89
u/l
0.36
1244
11208
550
3967
1.65
17.14
5.0
3.7
53.80
129.20
e6/l
2.48
397
2834
690
5277
1.63
16.92
9.3
6.0
26.58
27.43
%
1.20
646
4937
901
7365
1.67
16.90
5.7
4.6
370.16
2114.81
e6/l
1.26
19
113
1256
11371
2.44
16.86
24.6
17.5
3.98
3.98
mmol/l
0.06
1230
11051
695
5329
1.62
16.83
18.9
16.2
1.25
1.28
inr
0.40
187
1521
681
5201
1.62
16.72
8.9
5.8
58.46
57.57
%
1.10
635
4858
1253
11342
2.40
16.65
24.1
17.4
139.53
139.64
mmol/l
0.75
1228
11039
47
120
4.02
16.64
2.2
2.0
10640.00
1400.00
titre
—
5
6
1146
10050
1.91
16.44
5.3
4.7
3.86
2.07
mu/l
0.49
1061
9142
1156
10171
1.93
16.35
7.1
5.7
40.80
39.66
mmol/mol
3.48
1078
9378
482
3418
1.64
15.73
4.3
3.3
39.65
86.79
e6/l
1.35
375
2640
306
1925
1.76
15.62
3.3
2.7
1.17
1.30
e6/l
0.17
192
1105
32
64
5.10
15.30
2.8
2.3
469.36
645.71
e6/l
0.60
25
59
27
47
5.84
14.96
1.7
3.1
673.15
1159.60
u/ml
0.90
27
47
738
5841
1.58
14.91
7.7
6.4
11.63
11.60
umol/l
0.03
710
5541
600
4551
1.57
14.43
2.7
2.2
78.03
78.11
nmol/l
0.02
548
4040
407
2819
1.63
14.33
6.1
3.9
89.03
88.94
%
0.02
398
2748
696
5482
1.55
14.02
4.7
3.7
0.00
0.00
estimate
0.50
105
990
284
1799
1.73
13.99
3.3
2.9
2.11
2.45
e6/l
0.39
168
984
24
40
6.09
13.88
24.1
29.3
110.61
133.22
ug/l
0.85
18
32
689
5436
1.54
13.62
6.1
5.0
0.00
0.00
estimate
-0.00
107
1017
687
5432
1.54
13.34
4.7
3.8
0.00
0.00
estimate
0.75
111
1088
1072
9389
1.68
13.23
25.5
17.8
14.91
15.05
%
0.37
1050
9213
322
2138
1.66
13.23
4.6
3.9
688.59
365.71
ng/l
0.56
254
1715
469
3419
1.57
13.08
3.1
3.1
2285.42
1518.07
ng/l
0.85
413
2915
970
8321
1.58
12.69
4.4
3.9
14.78
14.88
pmol/l
0.52
890
7514
1296
12114
2.63
12.45
31.4
22.0
39.87
40.29
%
0.48
1210
11290
1297
12130
2.64
12.40
31.5
22.0
133.52
134.67
g/l
1.96
1281
11934
1296
12121
2.62
12.30
31.4
21.9
245.33
248.17
e9/l
0.85
1269
11794
1296
12125
2.61
12.22
31.3
21.9
6.79
6.72
e9/l
0.28
1267
11766
1296
12127
2.60
12.18
31.3
21.9
4.44
4.46
e12/l
1.14
1265
11771
159
881
1.91
12.07
3.4
2.7
61.75
64.72
ml/min/173m2
0.35
54
366
349
2412
1.60
12.07
3.5
2.6
4.51
5.70
e6/l
1.63
308
2171
595
4628
1.51
12.06
4.2
2.7
142.92
135.69
ug/l
0.23
547
4245
179
1034
1.84
11.94
8.7
3.5
1.53
2.05
mmol/l
1.26
155
852
27
58
4.73
11.91
1.1
1.2
—
—
—
0
0
1207
11016
1.88
11.85
5.8
4.9
2.60
2.73
mmol/l
5.12
1123
10085
45
143
3.22
11.59
1.2
1.2
4.27
6.78
u/ml
0.52
26
63
441
3244
1.53
11.49
4.1
3.1
901.36
275.44
mg/l
1.17
309
2056
600
4719
1.49
11.28
2.1
2.0
90.52
94.48
pmol/l
1.31
310
2389
427
3130
1.53
11.27
4.1
3.1
0.32
0.45
e6/l
0.90
328
2388
842
7093
1.49
11.17
3.8
3.1
54.03
49.68
u/l
0.52
804
6593
174
1018
1.81
11.11
2.7
2.4
5.33
6.85
ug/l
0.73
154
886
1183
10775
1.78
11.09
5.2
4.4
4.48
4.63
mmol/l
5.45
1102
9931
27
62
4.42
11.01
2.4
2.0
—
—
—
0
0
82
367
2.31
10.92
2.0
1.6
208.00
136.00
titre
—
5
15
165
959
1.82
10.75
3.1
2.8
67.00
66.38
g/l
0.50
147
877
25
55
4.61
10.73
2.1
1.4
—
—
—
0
0
25
55
4.61
10.73
2.1
1.4
—
—
—
0
0
71
301
2.43
10.68
2.1
2.1
13.37
11.74
mg/l
0.51
66
276
207
1288
1.72
10.67
5.7
2.5
1.73
1.79
%
0.41
184
1127
206
1284
1.71
10.54
5.5
4.2
227.76
254.61
u/l
2.39
193
1205
142
793
1.88
10.50
3.5
2.8
10.29
10.66
g/l
0.47
132
718
505
3889
1.48
10.28
3.4
3.4
2.35
2.36
mmol/l
0.19
450
3396
1173
10712
1.71
10.19
5.1
4.4
1.44
1.46
mmol/l
0.81
1087
9815
45
155
2.97
10.15
5.2
3.1
158.00
1679.61
u/ml
—
6
18
15
9
16.84
9.88
5.1
6.6
—
—
—
0
0
232
1517
1.64
9.86
11.6
5.4
1.07
1.03
mmol/l
0.99
219
1388
389
2864
1.50
9.81
2.6
2.1
3.14
3.04
mg/l
0.21
333
2408
1140
10359
1.64
9.80
18.6
13.9
77.45
79.13
ml/min/173m2
1.62
958
8535
72
321
2.31
9.70
1.6
1.6
1.36
20.77
iu/ml
0.45
19
58
126
695
1.90
9.67
2.6
2.5
18.88
27.73
au/ml
0.40
11
46
33
97
3.46
9.63
2.0
2.3
—
—
—
0
0
48
177
2.77
9.58
2.3
1.4
121.14
109.45
u/ml
0.48
14
33
42
144
2.98
9.56
1.1
1.1
—
—
—
0
0
103
533
2.01
9.52
2.1
1.9
1.48
1.61
g/l
0.57
89
459
459
3511
1.46
9.50
4.6
3.2
35.52
33.45
u/l
0.42
436
3324
164
997
1.73
9.14
3.0
3.0
225.63
218.27
ng/l
0.09
144
919
230
1529
1.61
9.10
4.0
2.5
21.29
22.68
%
0.84
191
1311
166
1018
1.72
8.97
14.2
7.0
11.08
9.96
mmol/l
1.21
160
969
448
3443
1.45
8.93
4.8
3.6
14.37
8.20
mg/mmol
1.15
309
2163
40
139
2.93
8.91
1.1
1.1
118.34
118.79
%
0.02
35
127
446
3439
1.44
8.69
4.0
3.1
6.80
7.51
mmol/l
3.17
391
2894
191
1228
1.65
8.63
4.8
2.8
10.02
8.77
umol/l
0.28
163
1058
1166
10731
1.62
8.62
5.3
4.6
6.09
5.95
mmol/l
2.52
1071
9727
1132
10347
1.57
8.61
4.6
3.9
1.31
1.29
mmol/l
0.20
1046
9407
41
148
2.83
8.54
1.2
1.2
2.47
3.67
u/ml
0.27
17
46
238
1623
1.57
8.41
4.0
2.4
2.26
2.31
g/l
0.59
217
1504
449
3487
1.43
8.34
3.4
2.5
53.92
83.87
u/l
0.71
418
3207
148
897
1.73
8.33
6.0
3.7
106.66
87.42
ng/l
1.02
130
773
82
413
2.05
8.19
2.5
2.7
2.83
2.98
g/l
0.62
74
372
86
442
2.01
8.13
2.4
2.6
—
—
—
0
0
86
442
2.01
8.13
2.4
2.6
7.31
7.40
g/l
0.20
78
401
86
442
2.01
8.13
2.4
2.6
3.69
3.62
g/l
0.12
78
401
49
201
2.49
7.97
1.4
1.2
—
—
—
0
0
47
190
2.53
7.88
1.5
1.2
299.63
257.99
u/ml
0.46
35
111
69
332
2.14
7.78
2.3
1.9
—
—
—
0
0
276
1980
1.49
7.66
1.6
1.5
2.20
2.47
g/l
1.87
165
1169
200
1341
1.58
7.57
6.7
7.7
4.93
5.12
kpa
2.16
188
1280
320
2378
1.45
7.40
2.7
1.7
1.14
1.22
mg/l
0.20
250
1823
16
21
7.70
7.39
1.1
1.0
—
—
—
0
0
199
1342
1.57
7.34
6.7
7.7
12.51
12.15
kpa
0.35
187
1286
80
416
1.98
7.34
2.5
2.7
10.08
10.45
g/l
0.37
72
373
359
2733
1.43
7.27
1.6
1.5
22.84
20.49
nmol/l
1.35
302
2303
257
1849
1.48
6.99
5.4
3.2
0.81
0.82
mmol/l
0.50
239
1728
746
6433
1.36
6.93
2.8
2.8
—
—
—
0
0
322
2425
1.43
6.88
5.4
4.1
1.02
1.02
kg/l
0.04
42
346
294
2182
1.44
6.79
2.8
3.0
2.45
2.46
mmol/l
0.16
261
1917
247
1773
1.48
6.78
4.1
2.4
11.83
12.90
umol/l
1.62
230
1653
179
1200
1.57
6.76
7.0
8.1
95.19
95.52
%
0.22
172
1157
198
1359
1.54
6.73
2.1
1.8
—
—
—
0
0
196
1347
1.53
6.62
6.8
7.7
0.39
1.22
mmol/l
2.16
153
1076
294
2196
1.43
6.53
1.8
1.7
1175.40
1192.99
nmol/l
0.10
233
1618
62
311
2.04
6.32
5.2
2.5
3.52
3.63
g/l
0.22
57
299
366
2859
1.38
6.25
1.7
1.6
1.27
1.39
mmol/l
1.99
318
2402
529
4384
1.34
6.16
3.9
3.8
95.25
49.29
ng/l
0.38
394
3123
98
580
1.74
6.03
2.8
3.4
4.34
4.51
pmol/l
0.79
85
504
28
100
2.84
6.02
2.4
2.2
—
—
—
0
0
113
701
1.67
5.86
5.6
2.9
127.40
127.35
g/l
0.01
107
687
28
102
2.78
5.81
1.3
1.2
—
—
—
0
0
192
1352
1.49
5.76
2.1
1.8
—
—
—
0
0
131
850
1.60
5.69
2.1
1.6
—
—
—
0
0
365
2889
1.36
5.66
3.5
2.7
5669.79
6345.04
umol/l
0.10
328
2515
611
5214
1.31
5.65
3.4
2.6
—
—
—
0
0
162
1106
1.53
5.63
7.6
8.5
119.91
121.01
g/l
0.28
157
1078
153
1032
1.54
5.62
3.3
2.4
42.88
38.65
u/l
0.19
138
880
117
742
1.63
5.58
7.9
7.0
23.96
24.54
mmol/l
1.08
110
706
70
384
1.87
5.54
1.4
1.3
0.41
1.09
u/ml
—
8
30
177
1239
1.49
5.46
2.1
2.3
154.94
127.89
ug/g
0.31
137
1001
69
382
1.85
5.32
2.7
2.8
0.88
1.27
g/l
0.41
60
335
255
1935
1.39
5.09
2.3
1.9
—
—
—
0
0
288
2241
1.36
4.91
1.3
1.2
2.10
1.59
u/ml
0.24
77
590
61
339
1.84
4.68
2.9
2.7
0.02
0.02
g/l
0.00
56
313
363
2944
1.32
4.66
5.5
4.1
0.00
0.00
estimate
0.69
102
981
51
268
1.94
4.64
1.1
1.2
1.92
13.16
u/ml
—
5
46
63
356
1.81
4.59
2.8
2.6
36.71
37.73
g/l
0.63
55
315
58
321
1.84
4.52
2.9
2.8
0.00
0.00
g/l
-0.00
53
298
14
32
4.41
4.44
1.4
1.1
1522.14
1596.37
miu/ml
0.07
14
32
492
4179
1.28
4.40
5.0
4.0
—
—
—
0
0
58
324
1.83
4.40
2.9
2.7
0.00
0.00
g/l
-0.00
53
299
338
2738
1.31
4.34
3.2
2.4
—
—
—
0
0
20
72
2.80
4.29
2.6
2.7
41.67
40.68
%
—
7
42
236
1816
1.36
4.29
1.3
1.3
44.87
34.58
iu/ml
0.39
76
589
150
1074
1.45
4.14
2.7
2.2
0.21
0.21
g/l
0.07
142
1004
10
17
5.92
4.13
1.2
3.1
—
—
—
0
0
14
35
4.03
4.10
3.3
2.3
—
—
—
0
0
8
10
8.04
4.06
1.0
1.2
—
—
—
0
0
227
1751
1.36
4.05
1.2
1.2
15.84
12.68
u/ml
0.24
82
657
137
987
1.43
3.67
2.2
2.1
396.46
374.14
nmol/l
0.76
125
896
32
156
2.08
3.63
1.6
1.7
—
—
—
0
0
60
361
1.69
3.58
1.4
1.2
—
—
—
0
0
55
325
1.72
3.51
1.4
1.5
229.25
280.59
ug/g
1.16
30
183
48
273
1.79
3.49
2.4
1.3
441.40
508.22
mg/l
0.91
42
256
296
2426
1.28
3.40
1.8
1.7
24390725.97
25589993.15
pmol/l
0.02
246
1993
27
127
2.15
3.37
1.3
1.3
—
—
—
0
0
7
10
7.03
3.36
10.3
5.4
0.45
0.25
umol/l
—
7
10
48
277
1.76
3.34
1.8
1.6
—
—
—
0
0
34
176
1.96
3.31
1.2
1.3
—
—
—
0
0
105
736
1.46
3.27
1.7
1.6
—
—
—
0
0
15
54
2.80
3.26
1.3
1.2
—
—
—
0
0
17
66
2.60
3.22
1.4
1.1
0.99
1.23
u/l
—
8
39
15
55
2.75
3.16
1.1
2.1
—
—
—
0
0
44
254
1.76
3.08
2.8
2.2
110.60
132.21
ug/min
0.15
28
158
50
300
1.69
3.06
1.4
1.3
—
—
—
0
0
181
1413
1.32
2.99
9.5
7.3
—
—
—
0
0
88
609
1.48
2.95
7.0
10.4
23.86
24.53
mmol/l
1.18
82
592
44
258
1.73
2.93
1.3
1.3
—
—
—
0
0
44
258
1.73
2.93
1.3
1.3
—
—
—
0
0
11
32
3.46
2.90
2.3
1.5
—
—
—
0
0
64
415
1.57
2.90
2.9
2.8
—
—
—
0
0
14
52
2.71
2.89
1.3
1.2
—
—
—
0
0
206
1647
1.30
2.86
1.5
1.5
—
—
—
0
0
19
83
2.31
2.85
2.9
2.2
645.42
601.12
ml
0.22
12
58
73
492
1.51
2.79
2.5
2.0
1.85
1.55
ug/l
0.18
65
434
16
65
2.48
2.79
1.2
1.2
—
—
—
0
0
9
23
3.93
2.77
2.4
1.3
—
—
—
0
0
422
3679
1.21
2.72
5.0
4.9
2.48
2.63
ug/l
0.15
385
3288
41
242
1.72
2.69
2.4
1.4
13.03
48.85
e6/l
0.77
34
188
41
242
1.72
2.69
2.5
1.5
62.51
727.33
e6/l
0.83
35
196
20
92
2.19
2.68
1.2
1.2
—
—
u/ml
—
0
0
43
258
1.69
2.66
1.2
1.1
—
—
—
0
0
41
243
1.71
2.65
2.4
1.2
3.78
3.76
mmol/l
0.03
36
228
30
164
1.85
2.54
1.2
1.6
—
—
—
0
0
16
69
2.33
2.49
1.2
1.2
—
—
—
0
0
42
258
1.65
2.41
1.3
1.3
—
—
—
0
0
5
8
6.27
2.37
1.2
1.0
—
—
—
0
0
13
52
2.51
2.36
1.4
1.4
0.69
1.29
nmol/l
—
8
40
15
65
2.32
2.32
1.5
1.1
—
—
—
0
0
50
327
1.55
2.24
1.8
1.7
—
—
—
0
0
12
48
2.51
2.19
3.5
4.2
—
—
—
0
0
9
30
3.01
2.15
1.1
1.3
—
—
—
0
0
49
323
1.54
2.14
1.6
1.7
—
—
—
0
0
41
260
1.59
2.11
4.1
2.7
8.41
8.00
kpa
0.90
41
251
22
117
1.89
2.07
3.4
1.8
—
—
—
0
0
25
139
1.81
2.06
1.2
1.1
—
—
—
0
0
67
476
1.43
2.04
7.7
5.2
1.60
1.60
%
0.01
60
447
6
15
4.01
2.04
2.0
2.3
—
—
—
0
0
6
15
4.01
2.04
1.2
1.3
—
—
—
0
0
338
2959
1.19
2.02
4.4
4.2
21.87
21.27
%
0.33
156
1411
11
44
2.51
2.01
1.0
1.2
—
—
—
0
0
152
1227
1.27
1.99
3.4
4.2
7.67
17.39
ug/l
1.11
121
1017
7
21
3.35
1.96
1.0
1.0
—
—
—
0
0
7
21
3.35
1.96
1.6
1.0
—
—
—
0
0
11
45
2.46
1.93
1.2
1.1
551.36
200.98
iu/ml
0.84
11
45
15
71
2.13
1.92
1.9
2.0
—
—
—
0
0
12
52
2.32
1.88
1.2
1.0
—
—
—
0
0
8
28
2.87
1.86
1.3
1.1
—
—
—
0
0
18
93
1.95
1.85
2.1
1.8
—
—
—
0
0
5
12
4.18
1.82
1.6
1.3
166.80
88.83
ng/l
—
5
12
23
130
1.78
1.82
3.3
1.7
—
—
—
0
0
68
497
1.39
1.79
1.1
1.0
—
—
—
0
0
50
347
1.46
1.75
1.5
1.3
29.18
30.58
iu/l
0.10
41
285
62
454
1.38
1.64
2.5
3.2
1590.52
3155.45
u/ml
0.28
50
395
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
13
63
2.07
1.60
1.3
1.2
—
—
—
0
0
21
121
1.75
1.59
4.2
3.6
—
—
—
0
0
5
15
3.34
1.52
4.8
1.3
—
—
—
0
0
36
242
1.50
1.51
1.6
1.4
7.50
9.18
u/l
0.43
29
188
60
445
1.36
1.49
2.7
1.9
—
—
—
0
0
51
368
1.40
1.49
3.7
3.7
44.56
69.82
mg/l
0.79
44
298
17
94
1.82
1.47
2.9
2.4
11.25
7.17
umol/l
0.31
11
60
51
369
1.40
1.47
3.7
3.8
30.93
61.08
mg/l
1.04
43
298
38
260
1.47
1.47
10.4
7.1
104.91
105.69
mmol/l
0.32
33
235
9
38
2.38
1.45
1.1
1.2
—
—
—
0
0
30
196
1.54
1.43
3.4
1.7
—
—
—
0
0
30
196
1.54
1.43
3.4
1.7
—
—
—
0
0
16
88
1.83
1.41
1.4
1.3
—
—
—
0
0
39
271
1.45
1.40
1.3
1.3
306.12
231.98
miu/ml
0.45
17
119
12
60
2.01
1.38
1.3
1.1
—
—
—
0
0
6
23
2.62
1.37
1.0
1.1
—
—
—
0
0
5
17
2.95
1.36
1.0
1.2
—
—
—
0
0
26
167
1.57
1.35
1.3
1.1
—
—
—
0
0
13
68
1.92
1.33
1.2
1.4
1.53
1.55
g/l
0.06
13
68
22
136
1.63
1.33
2.4
1.6
—
—
—
0
0
22
136
1.63
1.33
2.4
1.6
—
—
—
0
0
88
703
1.27
1.32
3.7
3.7
1.77
1.94
mmol/l
0.23
67
526
46
335
1.39
1.30
1.2
1.1
—
—
—
0
0
8
34
2.36
1.29
1.1
1.1
—
—
—
0
0
27
178
1.53
1.26
1.1
1.1
—
—
—
0
0
46
338
1.37
1.25
1.2
1.1
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
8
36
2.23
1.24
1.1
2.1
158.38
159.26
%
—
8
36
24
155
1.56
1.23
1.3
1.4
—
—
—
0
0
24
155
1.56
1.23
1.3
1.4
—
—
—
0
0
24
155
1.56
1.23
1.3
1.4
—
—
—
0
0
24
155
1.56
1.23
1.3
1.4
—
—
—
0
0
48
356
1.36
1.23
3.0
1.8
—
—
—
0
0
5
19
2.64
1.21
3.8
2.1
12.44
17.19
umol/l
—
5
19
41
297
1.39
1.21
4.4
2.8
23.92
24.82
mmol/l
0.81
41
290
18
110
1.64
1.15
1.5
1.6
—
—
—
0
0
18
110
1.64
1.15
1.3
1.3
—
—
—
0
0
16
95
1.69
1.14
1.1
1.0
—
—
—
0
0
7
30
2.34
1.12
1.4
1.1
—
—
—
0
0
13
73
1.79
1.11
1.0
1.0
440.38
255.50
ng/l
—
8
42
14
81
1.74
1.09
1.1
1.1
—
61.88
—
0
8
13
74
1.76
1.07
1.0
1.0
60.14
38.64
ng/l
—
7
42
13
74
1.76
1.07
1.0
1.0
797.67
641.20
ng/l
—
6
41
30
211
1.43
1.06
3.3
1.4
0.79
0.89
nmol/l
0.25
23
174
10
52
1.93
1.06
2.1
2.2
34.26
45.19
umol/l
—
10
40
7
33
2.13
1.05
1.4
1.2
—
—
—
0
0
94
780
1.22
1.05
2.4
2.2
12.39
12.70
nmol/l
0.11
85
703
7
34
2.06
1.03
1.6
1.1
—
—
—
0
0
34
247
1.39
1.02
2.6
2.1
126.52
127.85
g/l
0.11
29
184
83
683
1.23
1.01
1.2
1.2
143.99
136.65
iu/ml
0.05
22
270
110
935
1.19
0.98
4.2
3.9
1.24
1.23
mmol/l
0.87
95
815
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
52
407
1.29
0.97
2.8
2.6
0.29
0.36
u/ml
0.72
26
232
32
233
1.38
0.96
1.7
2.3
875.76
4651.32
u/l
—
9
93
24
166
1.45
0.94
1.4
1.5
—
—
—
0
0
34
252
1.36
0.92
1.6
1.8
7.62
4.60
iu/l
0.49
12
90
83
693
1.21
0.90
1.5
1.5
—
—
—
0
0
20
135
1.49
0.89
1.6
1.4
32586.00
36135.50
e6/l
0.07
13
74
8
42
1.91
0.88
1.0
1.0
—
—
—
0
0
137
1198
1.16
0.88
3.2
3.5
—
—
—
0
0
17
111
1.54
0.88
1.2
1.1
—
—
—
0
0
14
87
1.62
0.87
1.4
1.4
12.00
13.53
u/l
0.35
14
81
6
30
2.00
0.87
1.3
1.3
—
—
—
0
0
6
30
2.00
0.87
1.5
1.1
—
—
—
0
0
8
44
1.82
0.86
1.3
1.8
—
2284600.00
—
0
5
34
256
1.34
0.85
2.0
1.5
—
—
—
0
0
32
239
1.35
0.84
1.6
1.6
—
—
—
0
0
13
81
1.61
0.81
1.5
1.1
—
—
—
0
0
13
81
1.61
0.81
1.5
1.1
—
—
—
0
0
5
96
0.52
0.78
2.8
1.7
—
—
—
0
0
13
82
1.59
0.78
1.5
1.1
—
—
—
0
0
13
82
1.59
0.78
1.5
1.1
—
—
—
0
0
13
82
1.59
0.78
1.5
1.1
—
—
—
0
0
65
541
1.21
0.76
1.3
1.3
—
—
—
0
0
125
1415
0.87
0.76
4.8
4.5
34.48
32.56
%
1.17
92
947
7
39
1.80
0.72
1.0
2.0
—
—
—
0
0
7
40
1.75
0.71
2.7
2.9
—
—
—
0
0
7
40
1.75
0.71
2.7
2.9
—
—
—
0
0
232
2132
1.11
0.71
2.8
3.0
0.69
0.76
ug/l
0.63
159
1396
7
41
1.71
0.70
1.3
1.7
—
—
—
0
0
10
61
1.64
0.68
7.8
4.2
—
—
—
0
0
25
328
0.76
0.66
1.5
1.7
—
—
—
0
0
12
78
1.54
0.65
1.1
1.2
—
—
—
0
0
12
78
1.54
0.65
1.7
1.4
8.62
2.49
ug/l
0.48
12
65
11
70
1.58
0.65
4.5
1.9
—
—
—
0
0
12
79
1.52
0.62
1.1
1.2
—
—
—
0
0
8
50
1.60
0.61
1.4
1.3
—
—
—
0
0
18
133
1.36
0.55
13.6
5.4
7.27
7.48
mmol/l
0.11
18
111
136
1235
1.11
0.55
1.8
1.8
1.56
1.50
%
0.40
108
1070
27
214
1.27
0.52
4.5
3.2
4.25
4.21
e9/l
0.04
27
214
6
40
1.50
0.51
1.0
1.1
—
—
—
0
0
35
288
1.22
0.50
3.3
1.7
—
—
—
0
0
15
110
1.37
0.49
4.2
1.6
—
—
—
0
0
15
110
1.37
0.49
4.2
1.6
—
—
—
0
0
15
110
1.37
0.49
4.2
1.6
—
—
—
0
0
91
815
1.12
0.48
1.5
1.7
—
—
—
0
0
25
200
1.25
0.46
2.1
1.6
—
—
—
0
0
34
283
1.21
0.45
1.5
1.5
—
—
—
0
0
5
32
1.56
0.42
1.8
1.1
—
—
—
0
0
161
1499
1.08
0.41
1.3
1.4
—
—
—
0
0
5
33
1.52
0.41
1.2
1.2
117.80
107.85
%
—
5
26
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
27
222
1.22
0.41
5.2
3.3
60.33
57.90
%
0.55
27
222
34
287
1.19
0.40
1.6
1.6
16285.39
15875.31
e6/l
0.01
28
213
8
61
1.31
0.39
6.0
1.8
—
—
—
0
0
8
61
1.31
0.39
6.0
1.8
—
—
—
0
0
10
71
1.41
0.39
1.3
1.4
147.99
162.68
pmol/l
—
10
71
33
279
1.19
0.39
3.5
1.7
—
—
—
0
0
20
162
1.24
0.35
2.2
1.6
—
—
—
0
0
19
153
1.25
0.35
1.1
1.1
0.20
2.46
u/ml
—
10
83
27
318
0.85
0.33
1.2
1.4
—
—
—
0
0
6
46
1.31
0.33
1.0
1.1
—
—
—
0
0
6
46
1.31
0.33
1.5
1.2
—
65.71
%
—
0
7
25
210
1.19
0.33
3.8
1.8
—
—
—
0
0
13
101
1.29
0.31
1.6
2.0
0.86
2.60
u/field
—
7
42
31
269
1.16
0.29
1.7
1.8
37.13
38.99
nmol/l
0.27
31
259
7
57
1.23
0.29
1.0
1.4
—
78.18
—
0
11
16
130
1.23
0.28
2.6
1.8
—
—
—
0
0
31
270
1.15
0.28
1.3
1.4
—
—
—
0
0
49
444
1.11
0.25
2.2
1.9
—
—
—
0
0
9
75
1.20
0.25
1.9
1.4
—
—
—
0
0
9
75
1.20
0.25
1.8
1.4
—
—
—
0
0
17
142
1.20
0.24
2.0
2.4
55.33
26.29
mg/l
—
6
35
16
133
1.21
0.24
1.8
1.5
56.10
62.97
%
—
10
88
10
78
1.28
0.24
2.1
1.6
1.06
1.17
promille
—
10
58
15
124
1.21
0.24
1.5
1.4
6.37
6.49
mmol/l
0.05
15
115
53
485
1.10
0.23
2.8
2.0
—
—
—
0
0
5
40
1.25
0.22
2.6
2.3
28.76
17.12
ug/l
—
5
32
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
48
1.25
0.20
7.3
2.0
—
—
—
0
0
6
48
1.25
0.20
7.3
2.0
—
—
—
0
0
16
136
1.18
0.20
1.4
1.6
—
—
—
0
0
76
809
0.94
0.20
2.3
1.9
—
—
—
0
0
6
49
1.23
0.20
7.5
1.9
—
—
—
0
0
85
900
0.94
0.19
2.5
2.0
—
—
—
0
0
7
58
1.21
0.18
1.9
1.4
—
—
—
0
0
7
63
1.11
0.17
1.9
1.4
—
—
—
0
0
7
63
1.11
0.17
1.9
1.4
—
—
—
0
0
5
67
0.75
0.17
3.2
1.6
—
—
—
0
0
17
193
0.88
0.15
2.5
1.9
1.73
1.61
mmol/l
0.27
17
188
6
78
0.77
0.15
1.7
1.8
21.50
19.51
nmol/l
—
6
71
6
79
0.76
0.15
2.8
1.5
—
—
—
0
0
14
158
0.88
0.12
2.7
1.6
—
—
—
0
0
22
240
0.92
0.11
3.2
2.4
14.88
15.72
%
0.43
13
116
31
291
1.07
0.09
3.1
3.1
0.70
0.80
nmol/l
1.04
25
232
13
116
1.12
0.09
2.4
3.4
69.88
54.16
%
—
8
101
27
256
1.06
0.06
3.4
3.7
37.83
27.19
mg/l
0.60
18
165
10
111
0.90
0.06
1.5
1.4
—
—
—
0
0
27
257
1.05
0.05
2.0
1.4
—
—
—
0
0
27
282
0.96
0.04
1.1
1.2
—
—
—
0
0
14
149
0.94
0.03
2.4
1.5
—
—
—
0
0
16
151
1.06
0.03
2.4
1.5
—
—
—
0
0
33
320
1.03
0.03
1.4
1.4
—
—
—
0
0
12
112
1.07
0.03
1.4
1.3
119.25
338.04
u/l
5.44
12
107
14
148
0.95
0.02
2.6
1.6
—
—
—
0
0
20
192
1.04
0.02
1.3
1.4
—
—
—
0
0
11
103
1.07
0.02
1.2
1.3
12.00
30.97
%
—
6
67
14
147
0.95
0.01
2.6
1.6
—
—
—
0
0
14
147
0.95
0.01
2.6
1.6
—
—
—
0
0
20
194
1.03
0.00
1.6
1.9
217.50
211.21
pmol/l
0.10
20
183
12
124
0.97
0.00
1.0
1.0
0.48
2.76
u/ml
—
7
62
13
126
1.03
0.00
2.1
1.7
—
—
—
0
0
12
118
1.02
0.00
2.3
2.6
—
—
—
0
0
18
182
0.99
0.00
2.4
1.5
—
—
—
0
0
15
151
0.99
0.00
2.5
1.5
—
—
—
0
0
13
133
0.98
0.00
1.1
1.0
—
—
—
0
0
17
173
0.98
0.00
3.0
1.6
—
—
—
0
0
37
373
0.99
0.00
1.6
1.8
2.33
4.58
mg/l
0.70
26
283
12
115
1.04
0.00
1.1
1.3
17153.00
94075.35
e6/l
—
7
81
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
9
91
0.99
-0.00
1.4
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
77
0.91
-0.00
1.3
1.5
144.71
82.19
umol/l
—
7
77
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.0
—
—
—
0
0
6
59
1.02
-0.00
1.2
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
10
100
1.00
-0.00
1.4
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_RETINANAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINANAS | 0.998 [0.87, 1.15] | 0.977 |
| Birth year | 0.996 [0.99, 1.0] | 0.289 |
During the follow-up period (1.1.1998 — 31.12.2019), 685 out of 3642 females with H7_RETINANAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINANAS | 1.067 [0.91, 1.25] | 0.416 |
| Birth year | 0.988 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 601 out of 3031 males with H7_RETINANAS died.
Mortality risk
Mortality risk for people of age
years, who have H7_RETINANAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.1% | 0.25% |
| 5 | 0.647% | 1.275% |
| 10 | 1.654% | 3.094% |
| 15 | 3.085% | 6.093% |
| 20 | 5.306% | 10.422% |
Relationships between endpoints
↥Index endpoint: H7_RETINANAS – Other specified and unspecified retinal disorders
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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