Mandibular retrognathia AND surgery (BSSO)

K11_MN_RETRGN_AND_SURG

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

  • OPER_BSSRO
1382

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K07.13
  • Cause of death: ICD-10 K07.13

2 out of 7 registries used, show all original rules.

1031

4. Check minimum number of events

None

1031

5. Include endpoints

None

1031

6. Filter based on genotype QC (FinnGen only)

990

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6120 4159 1944
Only index persons 6048 4126 1922
Unadjusted period prevalence (%)
Whole population 0.10 0.12 0.05
Only index persons 0.13 0.15 0.07
Median age at first event (years)
Whole population 35.50 35.14 36.32
Only index persons 35.57 35.18 36.41

-FinnGen-

Key figures

All Female Male
Number of individuals 990 736 254
Unadjusted period prevalence (%) 0.22 0.26 0.12
Median age at first event (years) 38.01 36.92 41.16

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1031
Matched controls
10310
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
213.1
307.7
659
85
K07.13
ICD-10 Finland
Retrognaty, mandibular
+∞
307.7
1031
43
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
23.2
307.7
344
218
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
192.6
307.7
394
33
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
68.2
307.7
501
141
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
138.8
307.7
502
70
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
235.2
307.7
207
11
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
100.2
307.7
356
54
EEC05
NOMESCO Finland
Le Fort I osteotomy
187.1
307.7
197
13
SXC05
NOMESCO Finland
Other oral or dental procedure
17.4
307.7
398
359
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
107.8
307.7
253
31
SAA04
NOMESCO Finland
Special examination of mouth
25.0
307.7
427
283
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
49.1
307.7
227
59
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
206.3
307.7
564
60
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
+∞
307.7
1031
12
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
59.4
307.7
235
51
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
74.7
307.7
267
48
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
147.5
307.7
388
42
EB1MA
NOMESCO Finland
Cephalometry with X-ray
88.9
307.7
400
73
SBB10
NOMESCO Finland
Dental impressions
59.9
307.7
723
389
K07.24
ICD-10 Finland
Open bite
50.5
307.7
210
52
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
83.0
307.7
173
25
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
125.1
307.7
414
55
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
67.6
307.7
193
35
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
85.1
307.7
567
146
K07.23
ICD-10 Finland
Deep bite
99.4
307.7
431
74
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
143.3
307.7
535
77
SJC10
NOMESCO Finland
Orthodontic band in one tooth
247.8
307.7
531
44
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
192.8
307.7
623
81
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
41.3
301.9
187
55
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
100.7
283.2
147
17
K07.10
ICD-10 Finland
Asymmetry of jaw
129.3
267.4
135
12
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
8.3
247.3
471
952
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
25.1
245.6
180
86
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
135.7
238.7
120
10
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
112.0
232.2
119
12
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
119.9
229.9
117
11
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
12.3
219.7
246
257
EBB10
NOMESCO Finland
Insertion of dental implant
32.7
218.5
144
51
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
13.7
218.0
223
203
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
56.5
210.8
120
24
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
66.0
202.8
112
19
K07.60
ICD-10 Finland
Snapping jaw
9.2
196.5
282
406
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
7.8
186.7
319
558
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
57.1
181.6
103
20
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
8.7
173.8
256
377
K07.14
ICD-10 Finland
Retrognaty, maxillary
76.7
169.0
91
13
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
60.8
159.0
89
16
EBB15
NOMESCO Finland
Insertion of dental implant abutment
43.6
146.4
88
22
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
185.6
140.4
144
9
SAA03
NOMESCO Finland
Extended examination of mouth
4.9
126.6
726
3371
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
20.6
121.0
94
50
SPC20
NOMESCO Finland
Implant borne crown
26.6
116.0
81
33
WZC00
NOMESCO Finland
Treatment plan or consultation
4.1
109.1
608
2674
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
196.6
103.4
106
6
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
19.2
94.0
75
42
SXC03
NOMESCO Finland
Other oral or dental procedure
22.3
89.9
67
32
K01.0
ICD-10 Finland
Embedded teeth
10.6
85.2
97
100
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
14.2
84.4
79
60
EBA10
NOMESCO Finland
Operative extraction of tooth
3.9
82.7
318
1051
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
14.3
81.8
76
57
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
34.2
76.6
49
15
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
168.5
75.1
78
5
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
30.2
73.7
49
17
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
12.7
69.2
69
58
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
10.5
67.7
77
79
K00.00
ICD-10 Finland
Hypodontia
14.8
65.2
59
42
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
4.5
64.9
181
467
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
82.2
61.9
69
9
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
14.3
61.7
57
42
SJE90
NOMESCO Finland
Orthodontic finishing
115.5
60.6
65
6
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
623.1
60.4
59
*
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
25.7
59.8
42
17
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
27.7
58.4
40
15
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.8
58.0
589
3302
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
109.8
57.5
62
6
EB1S1
NOMESCO Finland
Photography of teeth
25.3
55.2
39
16
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
12.0
54.6
56
49
EDC30
NOMESCO Finland
Genioplasty
533.7
51.9
51
*
OIKK, ,
NOMESCO Finland
10.2
51.4
59
61
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
9.2
50.1
62
71
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
4.5
47.4
125
306
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
107.2
47.2
51
5
EB1WA, ,
NOMESCO Finland
17.9
46.5
38
22
Z3229
NOMESCO Finland
Other healthcare associate professional
4.2
42.8
125
330
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
5.9
42.5
80
146
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
14.1
41.0
38
28
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
9.8
40.9
48
51
SPC10
NOMESCO Finland
Standard dental crown
8.1
38.1
52
67
J01CE02
ATC
phenoxymethylpenicillin; oral
2.9
37.9
846
6346
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
101.3
36.0
39
*
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
12.9
35.9
35
28
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.8
35.9
218
904
ZXA10
NOMESCO Finland
Bilateral
2.8
35.8
211
861
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
48.5
34.9
42
9
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.2
34.2
96
245
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
46.1
33.0
40
9
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
46.1
33.0
40
9
SAA02
NOMESCO Finland
Basic examination of mouth
2.6
32.9
837
6410
EBA12
NOMESCO Finland
Demanding operative extraction of tooth
4.5
32.0
81
191
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
4.0
30.2
92
249
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
5.1
29.4
64
133
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
10.6
29.0
32
31
ZXE20
NOMESCO Finland
More than three and less than five hours
2.8
27.8
154
603
K01.17
ICD-10 Finland
Retained molar with obstruction in the lower jaw
4.5
26.6
66
153
EEC02
NOMESCO Finland
Rapid expansion of maxilla
133.2
24.7
26
*
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
49.6
24.4
29
6
K07.62
ICD-10 Finland
Habitual dislocation of the jaw joint
9.1
24.3
30
34
R06.5
ICD-10 Finland
Mouth breathing
2.8
23.4
124
473
SPA41
NOMESCO Finland
Precision impression for fixed dental prosthesis
5.6
23.1
44
81
WX704
NOMESCO Finland
Intubation
2.9
22.9
116
431
K07.4
ICD-10 Finland
Malocclusion, unspecified
5.3
22.6
46
90
SPAT1324
SPAT
Screening procedure
2.0
21.5
313
1843
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.9
21.4
439
2899
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
21.3
285
1628
SPB20
NOMESCO Finland
Temporary bridge
22.0
20.9
30
14
EFB50
NOMESCO Finland
Orthodontic procedure connected with ortognathic surgery
78.5
20.8
23
*
EBA40
NOMESCO Finland
Extraction of apex of root of tooth
8.4
20.6
27
33
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.9
19.3
311
1884
EDW99
NOMESCO Finland
Other operation on mandible
56.1
19.0
22
*
K07.61
ICD-10 Finland
Cracking jaw joint
4.3
18.8
50
122
K07.9
ICD-10 Finland
Dentofacial anomaly, unspecified
101.9
18.6
20
*
SCA02
NOMESCO Finland
Preventive oral health care
2.3
18.5
148
687
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
19.8
18.3
27
14
SPC08
NOMESCO Finland
Implant crown
19.8
18.3
27
14
SAA01
NOMESCO Finland
Simple examination of mouth
2.0
18.0
832
6931
WX720
NOMESCO Finland
Own respiration
3.4
17.6
65
200
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.5
16.9
60
180
J01FF01
ATC
clindamycin; systemic
1.9
16.6
291
1800
EB1TW
NOMESCO Finland
3D modelling of dentition
40.8
16.4
20
5
ZXX07
NOMESCO Finland
Extent of procedure, 7 units
162.4
15.5
16
*
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.8
15.3
332
2180
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
29.1
15.2
20
7
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.7
14.7
368
2510
EAB10
NOMESCO Finland
Excision and repair of frenum of lip
81.3
14.6
16
*
G47.3
ICD-10 Finland
Sleep apnoea
1.8
14.0
233
1408
G50.1
ICD-10 Finland
Atypical facial pain
4.6
13.8
33
74
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
+∞
13.6
13
*
WX725
NOMESCO Finland
Noninvasive ventilation
2.8
13.5
70
263
K07.00
ICD-10 Finland
Macrognatia (hyperplasia) of the upper jaw
141.8
13.5
14
*
SDA03
NOMESCO Finland
Periodontal treatment
1.6
13.4
460
3387
K07.68
ICD-10 Finland
Other disorders of the jaw joint
6.4
13.3
22
35
EBA00
NOMESCO Finland
Extraction of tooth
1.7
13.2
390
2761
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
13.1
342
2344
WX402
NOMESCO Finland
General anaesthesia
1.8
12.6
228
1407
EG1CG
NOMESCO Finland
Extensive MRI examination of mandibular joint with high intensity magnet
12.5
12.6
22
18
SPC09
NOMESCO Finland
Implant crown, demanding
70.8
12.6
14
*
SJD60, ,
NOMESCO Finland
+∞
12.5
12
*
SPC25
NOMESCO Finland
Other demanding attachment of prosthodontic crown
27.0
12.1
16
6
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
3.5
12.0
41
120
K07.0
ICD-10 Finland
Major anomalies of jaw size
47.2
11.9
14
*
SPA02
NOMESCO Finland
Preparation for dental prosthetics
3.6
11.8
39
112
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
+∞
11.5
11
*
G50.8
ICD-10 Finland
Other disorders of trigeminal nerve
17.3
11.2
17
10
EMAK, ,
NOMESCO Finland
2.7
11.1
58
219
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.9
11.0
51
180
N03AX16
ATC
[U] pregabalin
1.7
11.0
220
1394
QA9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head or neck, unspecified
43.8
10.9
13
*
WYA10
NOMESCO Finland
Emergency care or similar visit
2.1
10.8
101
498
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
11.4
10.6
19
17
SPAT1263
SPAT
Sampling
1.6
10.5
407
3035
K07.09
ICD-10 Finland
Anomaly in the size of the jaws UNS
+∞
10.4
10
*
EEC00
NOMESCO Finland
Segmental osteotomy of maxilla
+∞
10.4
10
*
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
16.2
10.4
16
10
ECA70
NOMESCO Finland
Regenerative periodontal surgery or gingival graft
13.3
10.2
17
13
XX3DW
NOMESCO Finland
Time consuming IT work
2.1
10.1
100
503
N02BE01
ATC
paracetamol; systemic, rectal
1.8
10.1
894
8040
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
9.9
324
2320
L07
ICPC
Jaw symptom/complaint
4.1
9.8
27
68
K06.00
ICD-10 Finland
Local gingivore traction
3.4
9.8
35
106
Z01.2
ICD-10 Finland
Dental examination
1.5
9.3
490
3874
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
9.2
440
3408
F45.8
ICD-10 Finland
Other somatoform disorders
2.0
9.0
108
582
Z50.1
ICD-10 Finland
Other physical therapy
2.6
9.0
50
195
ECA55
NOMESCO Finland
Complicated periodontal flap surgery
10.8
8.8
16
15
ZXX03
NOMESCO Finland
Extent of procedure, 3 units
9.6
8.8
17
18
ECB10
NOMESCO Finland
Reconstruction of gingiva
50.4
8.7
10
*
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
11.7
8.6
15
13
SCA01
NOMESCO Finland
Preventive oral health care, short
1.5
8.6
328
2416
SCD01
NOMESCO Finland
Removal of biofilm and supragingival calculus, short
7.0
8.6
20
29
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
27.8
8.5
11
*
K07.05
ICD-10 Finland
Micrognatia (hypoplasia) of both jaws
+∞
8.3
8
*
M79.1
ICD-10 Finland
Myalgia
1.7
8.3
166
1045
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
10.9
8.3
15
14
SXB10
NOMESCO Finland
Removal of attachments and rails from moth
9.5
8.3
16
17
TEG10
NOMESCO Finland
Injection of diagnostic or therapeutic substance into mandibular joint
14.6
8.2
13
9
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
9.0
8.1
16
18
ECU00
NOMESCO Finland
Removal of implant or external fixation device from alveoli
22.2
8.0
11
5
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.2
8.0
68
323
ZYC01
NOMESCO Finland
Remote contact by phone
2.1
8.0
72
350
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
7.8
212
1442
K07.33
ICD-10 Finland
Crowding of tooth or teeth
10.9
7.8
14
13
K12.2
ICD-10 Finland
Cellulitis and abscess of mouth
4.6
7.7
18
40
YEA05
NOMESCO Finland
Excision of gingival or connective tissue for transplantation
25.2
7.6
10
*
M01AE01
ATC
ibuprofen; systemic, rectal
2.1
7.5
966
9060
HAMTE, ,
NOMESCO Finland
4.5
7.4
18
41
EDC45
NOMESCO Finland
Reconstruction of mandible using bone graft
80.7
7.4
8
*
EGA00
NOMESCO Finland
Arthroscopy of mandibular joint
9.4
7.3
14
15
WX199
NOMESCO Finland
Other local analgesia
3.4
7.3
26
79
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.5
7.1
257
1858
ECB05
NOMESCO Finland
Mucogingival remodeling
6.6
7.1
17
26
XX2XT
NOMESCO Finland
Other injection with other radiological guidance
8.0
7.1
15
19
T84.62
ICD-10 Finland
Osteitis associated with dental implants
12.1
7.1
12
10
ZXX05
NOMESCO Finland
Extent of procedure, 5 units
10.1
7.0
13
13
SPF40
NOMESCO Finland
Removal and reattachment of crown or small bridge
3.9
7.0
20
52
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
16.8
6.8
10
6
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
22.7
6.7
9
*
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
2.0
6.6
70
362
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
6.6
328
2524
N06AX11
ATC
mirtazapine; oral
1.4
6.5
321
2462
EDC99
NOMESCO Finland
Other reconstructive operations on mandible
70.3
6.4
7
*
EEW99
NOMESCO Finland
Other operation on maxilla
70.3
6.4
7
*
TEG00
NOMESCO Finland
Punction of mandibular joint
14.4
6.4
10
7
K07.08
ICD-10 Finland
Other specified anomaly in the size of the cores
+∞
6.3
6
*
SJC20
NOMESCO Finland
Extraoral traction appliance arrangement incl. patient instructions
+∞
6.3
6
*
EGA05
NOMESCO Finland
Rinsing of mandibular joint
26.8
6.2
8
*
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
7.7
6.1
13
17
HMAK, ,
NOMESCO Finland
1.6
6.1
131
840
A02BC03
ATC
lansoprazole; oral
1.5
6.0
240
1764

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
45
143
3.24
11.63
3.6
3.2
—
—
—
0
0
501
3948
1.52
9.88
2.3
2.4
—
—
—
0
0
338
2462
1.55
9.48
2.5
2.6
—
—
—
0
0
519
4208
1.47
8.39
2.9
3.0
0.00
0.00
estimate
0.80
121
827
517
4251
1.43
7.41
2.9
3.0
0.00
0.01
estimate
1.06
108
770
512
4212
1.43
7.26
4.1
4.1
0.01
0.00
estimate
0.40
112
800
124
1922
0.60
6.76
3.1
3.4
99.35
96.98
%
0.51
118
1865
35
731
0.46
5.05
2.9
2.3
33.37
110.51
u/l
0.61
30
615
281
2197
1.38
4.90
3.0
3.3
0.00
0.01
estimate
1.28
112
790
690
6189
1.35
4.74
4.0
3.7
8.00
9.64
mm/h
4.54
657
5830
27
108
2.54
4.74
2.4
2.4
1.54
1.36
mmol/l
0.55
27
103
41
205
2.04
4.32
2.2
11.2
1.21
1.25
mmol/l
0.11
36
177
408
3443
1.31
4.12
2.7
2.8
6.03
5.87
ph
0.51
33
376
155
2069
0.70
3.91
3.9
6.1
—
—
—
0
0
90
591
1.57
3.83
3.5
4.1
1.03
0.75
%
0.26
17
173
16
56
2.89
3.64
1.5
2.4
—
—
—
0
0
863
8128
1.38
3.56
4.7
4.7
1.74
2.13
mu/l
0.91
830
7694
16
57
2.84
3.53
1.5
2.4
105.44
105.53
mmol/l
0.03
16
57
16
57
2.84
3.53
1.5
2.4
3.90
4.02
mmol/l
0.38
16
57
88
588
1.54
3.49
3.5
4.4
0.00
0.64
%
—
10
145
183
1410
1.36
3.40
1.5
1.6
61350152.39
38875927.09
pmol/l
0.20
163
1245
94
648
1.50
3.24
3.5
4.3
1.00
1.13
%
0.16
20
207
89
612
1.50
3.11
3.6
4.4
0.23
0.14
%
0.25
15
170
72
1059
0.66
3.02
2.3
2.4
2.78
3.60
e6/l
0.50
47
533
54
831
0.63
2.80
2.7
5.8
0.99
1.03
mmol/l
0.88
48
780
964
9327
1.52
2.79
10.1
9.9
—
—
—
0
0
628
5751
1.24
2.76
3.8
3.7
—
—
—
0
0
150
1905
0.75
2.68
2.1
2.5
—
—
—
0
0
901
8627
1.35
2.65
8.4
11.0
3.92
3.93
mmol/l
0.47
885
8404
424
3739
1.23
2.64
2.6
2.4
—
—
—
0
0
5
7
7.17
2.55
10.2
3.1
—
—
—
0
0
27
479
0.55
2.47
4.1
8.9
—
—
—
0
0
219
1809
1.27
2.44
3.0
3.2
1.02
1.02
kg/l
0.13
30
230
51
329
1.58
2.42
4.3
2.5
—
—
—
0
0
78
556
1.44
2.32
1.6
1.6
300.00
308.99
mu/l
0.07
70
496
43
269
1.62
2.32
1.6
1.7
35.84
39.06
nmol/l
0.43
43
264
47
302
1.58
2.28
1.0
1.1
4.96
3.41
u/ml
—
8
49
9
29
3.12
2.23
2.6
4.5
—
—
—
0
0
69
486
1.45
2.20
1.3
1.3
214.27
222.96
miu/ml
0.09
40
248
893
8598
1.29
2.06
8.4
10.9
139.91
139.66
mmol/l
3.51
876
8393
8
26
3.09
2.01
1.1
1.6
—
—
—
0
0
656
6131
1.19
1.99
5.5
6.9
70.66
74.90
u/l
3.77
636
5818
9
203
0.44
1.97
2.7
2.8
—
—
—
0
0
838
8025
1.24
1.92
11.8
13.3
333.44
333.05
g/l
0.69
832
7971
26
150
1.75
1.92
1.8
1.6
—
—
—
0
0
741
7014
1.20
1.90
4.4
4.1
14.41
14.39
pmol/l
0.08
710
6584
5
142
0.35
1.88
2.4
3.8
23.20
35.15
umol/l
—
5
131
66
898
0.72
1.88
2.2
2.6
4.49
6.60
umol/l
2.41
57
764
25
145
1.74
1.82
2.2
3.3
18.18
25.45
mg/l
0.66
16
90
42
616
0.67
1.81
1.3
1.3
—
—
—
0
0
47
322
1.48
1.77
2.0
2.1
—
—
—
0
0
15
283
0.52
1.75
1.1
1.1
—
—
—
0
0
7
24
2.93
1.72
2.4
5.3
—
—
—
0
0
160
1904
0.81
1.67
2.2
2.6
0.10
0.38
e6/l
5.81
131
1402
137
1654
0.80
1.63
3.4
4.0
—
—
—
0
0
85
656
1.32
1.63
2.4
2.2
6300.78
4230.53
u/l
0.26
37
272
39
262
1.51
1.63
2.2
3.3
25.62
25.35
mmol/l
0.26
39
254
279
2462
1.18
1.60
2.2
2.5
135.52
56.28
u/l
0.48
263
2312
1008
9937
1.65
1.58
14.7
15.8
259.66
261.68
e9/l
0.55
1003
9751
1009
9950
1.66
1.57
14.7
15.7
4.57
4.55
e12/l
1.01
1003
9756
11
50
2.21
1.57
1.9
2.0
—
—
—
0
0
215
1857
1.20
1.57
2.6
2.8
—
—
—
0
0
114
923
1.26
1.53
1.5
1.6
—
—
—
0
0
0
42
0.00
1.53
0.0
2.2
—
155.27
—
0
37
0
44
0.00
1.51
0.0
3.6
—
—
—
0
0
1009
9954
1.64
1.51
14.7
15.8
6.43
6.68
e9/l
2.24
1002
9748
1007
9930
1.61
1.51
14.5
15.8
40.40
40.58
%
0.37
950
9470
10
204
0.49
1.50
3.2
2.0
—
—
—
0
0
466
4300
1.15
1.48
2.7
2.7
70.45
89.76
ug/l
3.98
451
4078
7
28
2.51
1.45
1.9
2.0
—
—
—
0
0
950
9287
1.29
1.42
8.4
8.9
26.30
26.80
u/l
0.36
932
9062
28
181
1.56
1.41
1.0
1.0
3.35
1.56
u/ml
0.62
20
91
41
570
0.71
1.38
3.5
4.3
37.25
24.66
ug/l
0.19
32
443
14
247
0.56
1.35
1.3
1.2
—
1315.00
—
0
8
0
37
0.00
1.34
0.0
1.4
—
34.54
—
0
31
0
40
0.00
1.33
0.0
2.5
—
0.88
—
0
28
15
83
1.82
1.31
1.8
1.8
26.25
57.25
%
—
8
55
14
244
0.57
1.30
1.4
1.2
—
89.55
—
0
22
41
293
1.42
1.30
5.1
7.4
—
—
—
0
0
36
505
0.70
1.28
1.1
1.1
—
—
—
0
0
34
481
0.70
1.27
2.3
3.8
68.10
76.92
ng/l
0.50
29
442
147
1252
1.20
1.26
2.0
2.4
102.36
101.68
ug/g
0.01
114
1008
13
228
0.56
1.25
1.0
1.1
—
—
—
0
0
13
228
0.56
1.25
1.0
1.1
—
—
—
0
0
14
240
0.58
1.24
1.4
1.2
—
—
—
0
0
404
3733
1.14
1.20
7.6
7.9
0.00
0.00
e9/l
0.75
371
3069
8
38
2.11
1.18
1.3
1.8
1.42
1.43
nmol/l
—
8
31
272
3002
0.87
1.15
3.1
5.7
1.22
1.22
mmol/l
0.33
249
2769
0
35
0.00
1.15
0.0
25.3
—
7.59
—
0
30
66
520
1.29
1.15
3.0
3.1
1.23
1.23
mmol/l
0.19
61
448
190
2149
0.86
1.13
1.9
1.7
1.35
1.43
mmol/l
0.81
166
1865
899
8772
1.19
1.13
9.3
10.7
16.42
19.95
mg/l
2.70
692
6738
33
235
1.42
1.10
1.1
1.1
4.39
6.07
u/ml
0.23
17
120
21
136
1.56
1.09
1.4
2.7
5.13
4.99
kpa
0.48
21
136
21
136
1.56
1.09
1.4
2.7
2.14
2.47
mmol/l
0.32
16
89
21
136
1.56
1.09
1.4
2.7
8.99
9.08
kpa
0.11
21
136
161
1403
1.17
1.08
1.4
1.3
—
—
—
0
0
11
59
1.87
1.07
1.1
1.3
229.15
164.59
pmol/l
1.12
11
59
472
4427
1.12
1.07
3.0
4.4
6.20
6.43
mmol/l
1.73
425
4066
17
266
0.63
1.07
1.1
1.2
—
—
—
0
0
313
2864
1.13
1.07
8.5
8.1
1.10
1.10
inr
0.02
127
910
81
662
1.24
1.06
3.5
3.6
4.50
4.61
pmol/l
0.57
72
594
234
2103
1.15
1.05
2.3
2.3
—
—
—
0
0
12
67
1.80
1.05
1.3
1.2
—
—
—
0
0
5
22
2.28
1.03
1.0
1.5
—
—
—
0
0
46
351
1.33
1.02
1.1
1.3
10.51
10.47
u/l
0.01
37
285
177
1995
0.86
1.01
2.6
3.6
7.40
7.40
ph
0.09
44
373
73
890
0.81
1.00
1.6
2.3
25.38
24.68
%
0.15
60
769
849
8265
1.15
1.00
3.3
3.4
1.27
1.28
mmol/l
0.25
824
7836
23
156
1.49
0.99
1.2
1.4
6.48
7.21
mmol/l
0.76
16
142
38
502
0.75
0.98
2.7
1.7
1.25
1.36
g/l
0.29
38
471
160
1406
1.16
0.98
1.5
1.4
—
—
—
0
0
0
29
0.00
0.98
0.0
1.0
—
—
—
0
0
0
30
0.00
0.97
0.0
1.3
—
2169.89
—
0
18
0
32
0.00
0.95
0.0
1.4
—
—
—
0
0
94
1108
0.83
0.93
2.1
3.3
0.85
0.82
mmol/l
1.10
86
1057
99
840
1.20
0.92
1.2
1.2
75.42
150.44
iu/ml
2.69
36
351
14
86
1.64
0.91
2.3
1.7
20.09
20.94
nmol/l
0.17
14
80
46
361
1.29
0.87
1.9
2.6
63.32
121.27
ng/l
2.27
40
318
23
161
1.44
0.87
1.4
2.7
7.43
7.42
ph
0.45
23
144
35
264
1.34
0.87
1.1
1.1
0.36
3.53
u/ml
3.57
18
129
12
72
1.67
0.85
1.0
1.1
—
—
—
0
0
879
8601
1.15
0.85
3.7
3.8
4.96
4.84
mmol/l
3.43
851
8224
6
31
1.94
0.84
1.0
1.1
0.29
2.25
u/ml
—
6
26
8
45
1.78
0.84
2.0
3.2
858.13
546.00
u/ml
—
8
45
94
803
1.19
0.83
1.9
2.0
364.14
372.78
nmol/l
0.15
86
750
180
1621
1.13
0.80
1.2
1.3
10.26
10.73
u/ml
0.04
89
684
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.9
—
—
—
0
0
0
25
0.00
0.79
0.0
1.4
—
—
—
0
0
15
98
1.54
0.78
3.3
1.4
94.34
47.40
mu/l
0.65
15
88
0
26
0.00
0.78
0.0
1.4
—
23750.91
—
0
11
5
99
0.50
0.78
2.8
4.0
—
—
—
0
0
0
27
0.00
0.77
0.0
1.1
—
—
—
0
0
43
341
1.27
0.77
2.1
3.2
140.77
131.84
g/l
2.48
43
334
0
28
0.00
0.76
0.0
2.9
—
—
—
0
0
0
28
0.00
0.76
0.0
1.0
—
—
—
0
0
63
524
1.22
0.75
1.3
1.4
—
—
—
0
0
37
289
1.29
0.75
1.2
1.2
—
—
—
0
0
840
8215
1.12
0.74
3.5
3.7
5.56
5.73
mmol/l
6.98
814
7716
9
55
1.64
0.73
1.0
1.1
—
—
—
0
0
242
2616
0.90
0.72
2.4
3.1
45.51
77.77
e6/l
0.54
167
1713
875
8584
1.13
0.70
3.6
3.7
1.53
1.49
mmol/l
2.04
848
8165
13
193
0.67
0.70
2.3
2.4
101.62
275.96
ug/l
2.50
13
178
89
771
1.17
0.69
1.2
1.4
27.45
28.11
iu/l
0.07
81
649
801
7822
1.11
0.69
11.1
12.8
13.96
14.34
%
1.60
788
7699
162
1784
0.89
0.67
2.3
3.3
896.41
384.96
mg/l
0.39
103
1157
135
1209
1.13
0.67
1.8
1.9
—
—
—
0
0
271
2524
1.10
0.67
1.9
2.0
—
—
—
0
0
7
43
1.63
0.67
1.3
1.7
0.74
2.82
nmol/l
—
7
34
20
145
1.39
0.66
1.1
1.5
—
—
—
0
0
292
2738
1.09
0.63
1.6
1.6
—
—
—
0
0
29
226
1.29
0.62
1.0
1.1
0.50
1.25
u/ml
—
9
84
217
2008
1.10
0.62
1.5
1.7
0.70
0.87
mg/l
1.19
162
1499
185
1699
1.11
0.61
1.3
1.3
28.81
27.43
iu/ml
0.07
65
562
27
345
0.78
0.61
1.6
2.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
0.05
—
0
20
0
21
0.00
0.60
0.0
2.2
—
2761.55
—
0
11
0
21
0.00
0.60
0.0
6.8
—
60.50
—
0
16
0
21
0.00
0.60
0.0
7.8
—
25.25
—
0
21
0
22
0.00
0.59
0.0
3.6
—
—
—
0
0
18
242
0.74
0.58
1.3
1.4
0.34
0.37
nmol/l
0.09
13
195
35
283
1.25
0.57
1.2
1.7
0.23
0.24
g/l
0.10
30
268
573
5539
1.08
0.57
2.8
2.9
—
—
—
0
0
85
963
0.87
0.57
1.5
1.4
—
—
—
0
0
13
90
1.45
0.55
2.0
2.0
—
—
—
0
0
101
1128
0.88
0.55
2.2
2.5
2.43
2.42
mmol/l
0.37
95
1002
146
1333
1.11
0.55
2.0
2.7
486.00
675.15
ng/l
0.50
118
1076
239
2236
1.09
0.54
1.3
1.3
1.50
1.50
u/ml
0.00
90
650
28
222
1.27
0.54
1.4
1.4
14.65
23.86
u/l
1.51
19
187
17
125
1.37
0.54
1.5
2.4
—
—
—
0
0
21
160
1.32
0.54
1.5
1.4
—
—
—
0
0
63
725
0.86
0.53
3.0
7.3
104.90
104.56
mmol/l
0.21
63
725
555
5370
1.07
0.52
3.5
3.6
1264.33
288.05
e6/l
—
9
61
184
1982
0.91
0.52
1.8
2.2
3423.99
4283.51
umol/l
0.14
169
1797
882
8689
1.10
0.52
3.9
4.1
3.02
2.91
mmol/l
3.28
855
8252
195
2093
0.92
0.51
2.2
2.7
20.94
60.75
e6/l
1.77
162
1573
146
1339
1.11
0.51
2.5
2.4
574.48
535.56
mosm/kgh2o
1.22
126
1163
66
576
1.16
0.50
2.9
3.1
—
—
—
0
0
33
400
0.82
0.50
1.5
1.5
—
—
—
0
0
354
3379
1.07
0.49
3.8
6.3
1.22
1.22
mmol/l
0.68
305
2887
415
3984
1.07
0.48
5.3
6.1
—
—
—
0
0
252
2668
0.93
0.48
1.6
1.7
99.90
97.68
pmol/l
0.36
135
1447
10
68
1.48
0.47
1.3
1.2
—
—
—
0
0
12
165
0.72
0.46
4.0
4.0
55.00
56.47
%
0.14
12
165
99
1093
0.90
0.46
1.5
2.2
15.85
14.55
umol/l
0.93
91
1024
18
232
0.77
0.46
1.3
1.2
—
—
—
0
0
456
4398
1.07
0.46
5.0
5.6
1.91
1.97
e9/l
0.75
436
3987
8
117
0.68
0.46
1.4
1.4
—
—
—
0
0
8
119
0.67
0.46
1.8
3.1
—
—
—
0
0
198
2110
0.92
0.45
2.1
3.1
8.29
8.07
mmol/l
0.26
188
1844
31
256
1.22
0.44
1.4
2.4
0.67
0.65
%
0.13
31
256
92
1017
0.90
0.44
1.2
1.2
—
—
—
0
0
12
86
1.40
0.44
1.2
1.5
—
—
—
0
0
10
69
1.45
0.44
1.1
1.4
10.06
10.14
umol/l
—
10
64
7
51
1.38
0.44
3.4
2.8
39157.14
38639.31
ug/l
—
7
51
12
163
0.73
0.44
1.0
1.1
—
—
—
0
0
142
1313
1.09
0.43
1.3
1.4
428.57
519.40
titre
0.48
28
266
57
499
1.15
0.43
3.0
2.1
—
—
—
0
0
149
1381
1.09
0.43
4.4
3.6
1.65
1.63
ug/l
0.05
140
1269
11
78
1.41
0.43
3.0
2.4
1.41
1.27
e9/l
0.25
11
71
11
151
0.73
0.43
1.4
1.2
—
—
—
0
0
11
151
0.73
0.43
1.2
1.1
—
—
—
0
0
454
4387
1.06
0.42
5.0
6.0
0.18
0.18
e9/l
0.02
432
3934
35
295
1.19
0.42
1.2
1.7
1.16
1.20
g/l
0.22
30
279
8
57
1.41
0.42
1.6
1.1
—
—
—
0
0
33
391
0.84
0.41
1.4
1.4
—
—
—
0
0
8
58
1.38
0.41
1.4
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
8.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
1.70
—
0
16
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
361.83
—
0
12
141
1309
1.09
0.40
1.6
1.6
—
—
—
0
0
90
989
0.90
0.40
1.7
2.0
28.12
29.38
s
2.11
84
964
0
18
0.00
0.40
0.0
2.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
5
35
1.43
0.39
1.6
3.4
—
—
—
0
0
181
1924
0.93
0.39
1.4
1.4
2.10
2.24
g/l
0.90
139
1262
23
187
1.24
0.39
1.1
1.1
2.19
5.29
u/ml
1.30
13
73
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.8
—
—
—
0
0
33
388
0.85
0.39
1.4
1.4
—
—
—
0
0
12
159
0.75
0.38
3.3
3.7
3.96
4.12
e9/l
0.09
12
159
75
828
0.90
0.37
1.5
1.4
—
—
—
0
0
18
224
0.80
0.37
1.4
4.8
—
—
—
0
0
91
993
0.91
0.36
1.5
2.2
2.60
2.42
g/l
2.49
83
922
21
256
0.82
0.36
1.7
1.4
79.41
134.57
pmol/l
0.49
21
251
196
2070
0.93
0.36
1.7
2.1
135.25
190.37
u/l
1.00
181
1971
262
2504
1.06
0.35
2.3
2.7
19.28
33.22
ng/l
1.02
126
1308
9
125
0.72
0.35
2.4
2.6
—
—
—
0
0
6
44
1.37
0.34
1.2
1.1
2607.67
1589.41
miu/ml
—
6
44
25
209
1.20
0.34
1.2
1.0
7.66
3.27
u/ml
0.46
18
102
31
361
0.85
0.34
1.8
1.7
—
—
—
0
0
64
578
1.11
0.33
1.7
1.8
—
—
—
0
0
136
1449
0.93
0.32
1.3
1.4
22.61
21.00
nmol/l
0.62
124
1288
10
74
1.35
0.32
1.3
1.8
—
—
—
0
0
6
47
1.28
0.32
1.0
1.2
—
—
—
0
0
40
351
1.15
0.32
2.1
8.1
—
—
—
0
0
42
370
1.14
0.32
1.2
1.3
—
—
—
0
0
64
580
1.11
0.31
1.7
1.8
—
—
—
0
0
27
230
1.18
0.31
1.1
1.1
1.20
2.12
u/ml
0.68
17
107
309
2980
1.05
0.31
3.3
3.2
27.85
30.12
u/l
0.76
294
2847
7
97
0.72
0.31
1.4
1.6
—
—
—
0
0
7
53
1.32
0.31
1.3
1.3
—
—
—
0
0
57
630
0.90
0.30
1.9
3.5
—
—
—
0
0
29
250
1.16
0.29
2.1
2.2
—
—
—
0
0
63
574
1.10
0.29
1.7
1.8
—
—
—
0
0
16
195
0.82
0.29
1.1
1.3
3.95
3.73
mmol/l
0.28
16
181
656
6449
1.05
0.29
2.6
3.0
40.67
40.79
u/l
0.01
633
6179
434
4228
1.05
0.28
5.0
5.6
0.53
0.54
e9/l
0.59
415
3745
178
1868
0.94
0.28
2.9
3.8
5.19
10.84
mg/mmol
1.37
123
1192
88
818
1.08
0.27
2.8
2.4
0.65
0.65
ug/l
0.01
43
448
15
122
1.23
0.27
2.2
2.1
16.64
17.15
%
—
7
58
5
71
0.70
0.26
1.0
1.1
267.20
285.73
mg/l
—
5
66
5
75
0.67
0.26
1.0
1.6
—
—
—
0
0
19
224
0.85
0.25
1.2
1.3
—
—
—
0
0
58
531
1.10
0.25
1.7
1.8
—
—
—
0
0
24
276
0.87
0.24
1.7
2.0
4.52
4.86
iu/l
—
8
111
419
4092
1.04
0.24
4.8
5.4
55.45
56.43
%
1.18
408
3889
78
727
1.08
0.23
2.7
3.2
—
—
—
0
0
433
4234
1.04
0.23
5.0
5.7
0.04
0.04
e9/l
0.20
412
3744
19
222
0.85
0.23
1.3
1.4
312.47
311.16
ug/g
—
10
125
60
553
1.09
0.23
1.1
1.2
—
—
—
0
0
232
2402
0.96
0.23
2.1
3.3
2.35
2.35
mmol/l
0.12
220
2206
63
583
1.09
0.23
1.2
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
3.4
—
5694.60
—
0
10
0
10
0.00
0.21
0.0
6.3
—
—
—
0
0
12
98
1.23
0.21
1.1
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
10.1
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
49
451
1.09
0.20
1.8
1.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
9
114
0.79
0.20
1.1
1.1
1.33
1.45
g/l
—
9
106
9
114
0.79
0.20
1.2
1.3
—
—
—
0
0
14
165
0.85
0.19
1.1
1.2
—
—
—
0
0
85
804
1.06
0.18
1.4
1.7
—
—
—
0
0
22
194
1.14
0.18
1.8
4.5
1.54
1.33
mmol/l
0.37
22
189
97
1020
0.95
0.18
1.8
2.0
—
—
—
0
0
12
100
1.20
0.18
1.3
1.4
—
—
—
0
0
61
571
1.07
0.18
1.6
1.7
—
—
—
0
0
15
174
0.86
0.18
1.1
1.6
—
—
—
0
0
7
60
1.17
0.18
6.7
7.0
—
—
—
0
0
17
195
0.87
0.17
1.2
1.6
158.94
1047.39
e6/l
0.73
17
160
493
4854
1.03
0.17
7.1
8.5
3.68
3.98
e9/l
3.03
461
4282
105
1003
1.05
0.17
1.5
1.6
1199.21
1187.14
nmol/l
0.06
86
797
7
63
1.11
0.17
1.3
1.2
—
—
—
0
0
22
246
0.89
0.16
2.3
3.5
0.18
0.27
g/l
—
8
109
341
3476
0.97
0.15
1.8
1.9
—
—
—
0
0
37
400
0.92
0.15
1.8
2.8
70.57
75.36
e9/l
0.36
28
285
186
1809
1.03
0.14
1.8
2.0
2.64
2.76
mg/l
0.33
170
1575
185
1901
0.97
0.14
1.9
2.0
—
—
—
0
0
54
509
1.06
0.14
2.2
3.3
2.27
1.92
mmol/l
0.52
45
426
420
4137
1.03
0.14
4.9
5.6
30.40
29.36
%
1.51
411
3941
25
274
0.91
0.14
1.6
3.1
—
—
—
0
0
18
201
0.89
0.13
1.6
1.8
—
—
—
0
0
61
580
1.05
0.12
1.2
1.2
63.60
24.32
au/ml
—
6
34
81
844
0.96
0.12
1.6
1.5
—
—
—
0
0
11
126
0.87
0.11
1.8
1.7
—
—
—
0
0
15
167
0.90
0.10
1.2
1.2
3.20
6.03
u/ml
—
5
65
33
351
0.94
0.10
1.2
1.2
—
—
—
0
0
5
44
1.14
0.10
1.2
1.1
—
12.32
—
0
9
182
1858
0.98
0.10
3.1
3.0
—
—
—
0
0
5
46
1.09
0.09
1.0
1.0
—
—
—
0
0
292
2962
0.98
0.09
3.6
4.7
37.27
36.87
g/l
0.76
277
2793
36
380
0.95
0.09
1.7
1.6
—
—
—
0
0
155
1518
1.02
0.08
1.7
1.7
—
—
—
0
0
6
57
1.05
0.08
1.0
1.2
—
—
—
0
0
99
964
1.03
0.08
1.4
1.4
—
—
—
0
0
7
65
1.08
0.08
1.4
1.3
71.71
71.52
umol/l
—
7
65
14
127
1.10
0.08
1.3
1.5
—
—
—
0
0
6
71
0.84
0.07
1.0
1.1
—
—
—
0
0
34
323
1.05
0.07
3.5
13.7
—
—
—
0
0
19
176
1.08
0.07
1.2
2.8
0.70
0.90
nmol/l
0.87
14
150
7
80
0.87
0.07
1.4
1.4
38.53
35.76
nmol/l
—
7
66
145
1423
1.02
0.07
1.9
2.3
5.93
7.86
e6/l
0.61
131
1278
14
153
0.91
0.07
1.0
1.1
11.80
3503.87
iu/ml
—
5
37
8
90
0.89
0.06
2.5
3.4
—
—
—
0
0
8
92
0.87
0.06
1.1
1.1
—
—
—
0
0
32
305
1.05
0.06
1.5
1.5
—
7.42
—
0
11
9
100
0.90
0.06
1.2
1.2
—
—
—
0
0
9
105
0.86
0.06
1.1
1.4
—
—
—
0
0
30
315
0.95
0.06
1.3
1.9
20.14
20.99
s
0.97
22
277
16
172
0.93
0.06
2.8
2.0
—
—
—
0
0
62
636
0.97
0.05
3.2
10.1
1.27
1.05
mmol/l
0.17
40
502
106
1078
0.98
0.04
1.2
1.2
—
—
—
0
0
123
1248
0.98
0.04
2.2
3.0
283.55
436.66
ng/l
0.32
55
739
246
2481
0.99
0.04
2.0
2.0
—
—
—
0
0
89
876
1.02
0.03
1.3
1.3
—
—
—
0
0
76
773
0.98
0.03
1.1
1.2
—
—
—
0
0
758
7563
1.01
0.03
4.2
4.5
37.81
38.32
mmol/mol
0.36
730
7188
399
4008
0.99
0.03
3.9
5.8
9.40
10.24
umol/l
1.95
382
3801
57
559
1.02
0.03
3.1
10.9
96.74
96.27
%
0.21
52
543
11
118
0.93
0.02
1.2
1.4
—
21.74
—
0
7
396
3944
1.01
0.02
4.9
5.6
2.89
2.79
%
0.43
387
3733
399
3975
1.01
0.02
5.2
5.9
8.23
8.10
%
0.38
389
3772
341
3396
1.01
0.02
2.0
2.2
77.92
74.63
nmol/l
1.47
326
3159
10
107
0.93
0.02
1.2
1.7
—
17.80
—
0
5
203
2022
1.00
0.01
1.8
1.7
—
—
—
0
0
64
634
1.01
0.00
2.4
2.2
21.70
24.19
au/ml
—
7
61
21
206
1.02
0.00
1.1
1.1
—
—
—
0
0
18
178
1.01
0.00
1.2
1.1
—
—
—
0
0
39
392
0.99
0.00
1.8
2.4
—
—
—
0
0
47
468
1.00
0.00
1.1
1.1
—
—
—
0
0
379
3792
1.00
0.00
5.0
5.7
0.71
0.69
%
0.23
369
3571
13
127
1.02
0.00
1.7
2.3
—
—
—
0
0
15
153
0.98
0.00
2.3
2.2
307.96
162.52
ug/min
—
9
99
17
167
1.02
0.00
1.1
1.4
112.50
103.28
u/ml
—
6
36
20
203
0.98
0.00
1.7
2.0
2.81
4.44
umol/l
3.27
13
147
18
179
1.01
0.00
1.1
1.4
—
—
—
0
0
38
385
0.99
0.00
1.6
2.9
5.03
5.17
kpa
0.73
38
370
17
175
0.97
0.00
1.0
1.0
0.03
0.13
u/ml
—
5
52
12
115
1.04
0.00
1.2
1.4
—
0.49
—
0
7
5
56
0.89
0.00
1.4
1.3
—
—
—
0
0
5
56
0.89
0.00
1.6
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
1.36
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
78
0.90
-0.00
1.4
1.5
1.01
0.99
g/l
—
7
78
6
62
0.97
-0.00
4.0
2.4
628.00
528.85
e6/l
—
6
54
6
67
0.89
-0.00
1.3
2.2
32.83
32.13
pg
—
6
67
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.8
—
0.27
—
0
9
0
6
0.00
-0.00
0.0
1.2
—
4.53
—
0
6
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
63
0.95
-0.00
1.2
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
2.50
—
0
6
0
5
0.00
-0.00
0.0
7.4
—
—
—
0
0
5
59
0.85
-0.00
2.6
2.5
36.80
56.28
%
—
5
54
9
96
0.94
-0.00
1.4
1.3
—
—
—
0
0
6
63
0.95
-0.00
2.2
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.6
—
69.33
%
—
0
6
7
71
0.99
-0.00
1.4
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
79
1.01
-0.00
1.1
2.1
—
—
—
0
0
7
69
1.01
-0.00
1.4
1.3
1.57
1.57
g/l
—
7
69
0
9
0.00
-0.00
0.0
1.7
—
15.46
—
0
9
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
59
0.85
-0.00
5.0
2.4
0.18
0.20
e9/l
—
5
53
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
16.17
—
0
8
0
8
0.00
-0.00
0.0
2.0
—
178.25
—
0
8
0
8
0.00
-0.00
0.0
2.0
—
3.53
—
0
8
0
8
0.00
-0.00
0.0
1.6
—
352.63
—
0
8

Mortality – FinRegistry

Association

Association between endpoint K11_MN_RETRGN_AND_SURG and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_MN_RETRGN_AND_SURG.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: K11_MN_RETRGN_AND_SURG – Mandibular retrognathia AND surgery (BSSO)

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data