Mandibular retrognathia

K11_MN_RETRGN

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K07.13
  • Hospital discharge: ICD-10 K07.13
  • Cause of death: ICD-10 K07.13

3 out of 7 registries used, show all original rules.

2841

4. Check minimum number of events

None

2841

5. Include endpoints

None

2841

6. Filter based on genotype QC (FinnGen only)

2708

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 54236 28196 25988
Only index persons 47897 25173 22724
Unadjusted period prevalence (%)
Whole population 0.77 0.81 0.73
Only index persons 0.90 0.93 0.87
Median age at first event (years)
Whole population 12.06 12.44 11.60
Only index persons 12.73 13.25 12.15

-FinnGen-

Key figures

All Female Male
Number of individuals 2708 1900 808
Unadjusted period prevalence (%) 0.58 0.67 0.37
Median age at first event (years) 35.88 34.45 39.26

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2841
Matched controls
28323
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
49.8
321.4
187
40
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
5.9
317.6
681
1435
SXC05
NOMESCO Finland
Other oral or dental procedure
6.6
307.7
949
1999
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
172.9
307.7
194
12
K07.60
ICD-10 Finland
Snapping jaw
8.0
307.7
623
962
K07.24
ICD-10 Finland
Open bite
24.5
307.7
498
244
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
6.7
307.7
1052
2279
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
7.0
307.7
594
1032
SBB10
NOMESCO Finland
Dental impressions
20.0
307.7
1874
2498
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
32.0
307.7
276
95
EEC05
NOMESCO Finland
Le Fort I osteotomy
99.5
307.7
263
29
K07.23
ICD-10 Finland
Deep bite
24.2
307.7
1207
839
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
19.6
307.7
1237
1073
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
12.0
307.7
670
710
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
94.7
307.7
298
35
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
16.2
307.7
1020
947
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
15.6
307.7
454
341
EB1MA
NOMESCO Finland
Cephalometry with X-ray
16.1
307.7
1038
978
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
14.4
307.7
772
717
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
9.5
307.7
721
978
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
20.8
307.7
1167
919
K07.13
ICD-10 Finland
Retrognaty, mandibular
+∞
307.7
2841
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
18.0
307.7
798
602
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
624.7
307.7
1036
26
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
11.4
307.7
537
568
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
17.6
307.7
704
520
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
6.8
307.7
615
1111
SJC10
NOMESCO Finland
Orthodontic band in one tooth
18.5
307.7
995
802
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
13.7
307.7
1043
1150
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
20.4
307.7
1052
793
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
18.6
307.7
1221
1101
K07.10
ICD-10 Finland
Asymmetry of jaw
56.0
307.7
218
42
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
6.1
307.7
703
1439
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
25.5
307.7
365
163
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
18.1
307.7
467
305
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
77.4
307.7
175
24
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
12.1
307.7
904
1053
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
10.4
307.7
450
505
SAA04
NOMESCO Finland
Special examination of mouth
11.7
307.7
1049
1347
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
11.3
307.7
1185
1682
K07.14
ICD-10 Finland
Retrognaty, maxillary
31.3
306.6
202
69
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
5.9
297.1
622
1277
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
6.4
294.0
557
1039
EBB10
NOMESCO Finland
Insertion of dental implant
20.7
292.0
226
118
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
13.4
263.2
257
209
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
6.3
261.7
499
932
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
51.1
252.6
146
30
SAA03
NOMESCO Finland
Extended examination of mouth
4.0
251.3
2029
10910
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
7.3
240.6
385
599
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
64.6
235.2
130
21
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
33.9
203.0
130
40
EBB15
NOMESCO Finland
Insertion of dental implant abutment
24.0
199.6
144
63
WZC00
NOMESCO Finland
Treatment plan or consultation
3.1
193.7
1598
8223
SPC20
NOMESCO Finland
Implant borne crown
23.7
185.1
134
59
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
12.9
180.5
178
146
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
54.3
175.3
100
19
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
47.1
163.4
96
21
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
14.5
158.1
145
105
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
4.7
156.8
409
988
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
46.3
152.5
90
20
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.8
151.8
1694
9807
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
13.4
146.3
140
109
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
11.0
144.8
158
151
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
4.4
122.1
332
823
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.9
119.1
397
1142
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
10.3
117.6
134
136
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
20.3
113.1
87
44
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
8.4
112.4
150
187
SXC03
NOMESCO Finland
Other oral or dental procedure
14.2
111.7
103
75
EB1WA, ,
NOMESCO Finland
16.4
107.0
91
57
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
7.8
104.8
149
200
SJE90
NOMESCO Finland
Orthodontic finishing
12.2
104.8
106
90
K00.00
ICD-10 Finland
Hypodontia
6.3
100.1
174
290
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
4.2
99.7
290
753
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
44.6
95.7
57
13
OIKK, ,
NOMESCO Finland
3.3
92.7
388
1286
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
12.7
91.5
90
73
K01.0
ICD-10 Finland
Embedded teeth
5.1
87.8
191
392
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
6.0
87.2
158
274
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
29.5
86.9
58
20
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
5.3
82.5
172
340
G47.3
ICD-10 Finland
Sleep apnoea
2.4
79.8
673
3207
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
14.1
79.1
73
53
OIKAK, ,
NOMESCO Finland
27.4
79.0
54
20
SPB20
NOMESCO Finland
Temporary bridge
19.1
78.6
62
33
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
13.5
78.3
74
56
R06.5
ICD-10 Finland
Mouth breathing
3.1
78.1
370
1314
EB1S1
NOMESCO Finland
Photography of teeth
11.0
77.3
83
77
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.6
74.8
511
2200
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
6.1
74.3
131
221
EBA10
NOMESCO Finland
Operative extraction of tooth
2.4
73.9
666
3255
EB1TW
NOMESCO Finland
3D modelling of dentition
23.4
73.2
53
23
OIKH, ,
NOMESCO Finland
3.4
72.1
287
917
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
3.3
71.6
301
994
SJB30
NOMESCO Finland
Extraoral traction arrangements and operation instruction, removable appliance
5.5
70.8
141
267
OIKNV, ,
NOMESCO Finland
11.5
69.8
73
65
SPC10
NOMESCO Finland
Standard dental crown
7.5
69.4
101
139
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.8
66.9
218
610
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
16.4
64.9
55
34
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
80.7
63.2
71
9
OIKON, ,
NOMESCO Finland
8.3
63.1
84
104
EDC30
NOMESCO Finland
Genioplasty
165.7
62.1
65
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.0
60.9
301
1089
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
11.0
59.8
64
59
OIKAL, ,
NOMESCO Finland
4.0
59.7
177
463
OIKKK, ,
NOMESCO Finland
10.2
56.5
64
64
SJC20
NOMESCO Finland
Extraoral traction appliance arrangement incl. patient instructions
6.3
53.5
91
148
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
11.9
52.2
53
45
SAA02
NOMESCO Finland
Basic examination of mouth
2.1
51.9
2326
19255
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
8.2
49.4
66
82
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
8.7
49.3
63
74
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
3.3
48.1
194
622
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
6.5
47.1
77
120
OIKPU, ,
NOMESCO Finland
8.7
46.4
59
69
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
6.8
45.3
71
106
EMAK, ,
NOMESCO Finland
3.4
44.0
168
520
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
7.6
43.6
62
83
OIKJA, ,
NOMESCO Finland
5.9
42.7
78
136
EG1CG
NOMESCO Finland
Extensive MRI examination of mandibular joint with high intensity magnet
9.4
41.7
50
54
EBA12
NOMESCO Finland
Demanding operative extraction of tooth
3.1
41.6
182
612
G50.1
ICD-10 Finland
Atypical facial pain
5.5
40.4
79
147
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.7
40.3
973
6502
K07.4
ICD-10 Finland
Malocclusion, unspecified
3.9
38.7
115
301
OIKVA, ,
NOMESCO Finland
3.1
37.6
160
529
SAA01
NOMESCO Finland
Simple examination of mouth
1.9
37.2
2270
19316
K07.62
ICD-10 Finland
Habitual dislocation of the jaw joint
6.4
36.6
61
97
SPC08
NOMESCO Finland
Implant crown
11.7
35.9
37
32
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.2
35.9
149
485
OIKRE, ,
NOMESCO Finland
5.2
35.3
73
143
ECA70
NOMESCO Finland
Regenerative periodontal surgery or gingival graft
13.3
34.7
33
25
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.6
34.7
1124
8046
K07.61
ICD-10 Finland
Cracking jaw joint
3.4
33.4
121
362
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
3.6
33.3
114
329
SPA41
NOMESCO Finland
Precision impression for fixed dental prosthesis
4.7
33.1
77
167
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
10.7
33.0
36
34
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
9.2
32.9
40
44
WYA10
NOMESCO Finland
Emergency care or similar visit
2.2
32.8
288
1360
EEC02
NOMESCO Finland
Rapid expansion of maxilla
117.7
32.7
35
*
SPF40
NOMESCO Finland
Removal and reattachment of crown or small bridge
5.8
32.3
59
103
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
6.2
32.1
55
90
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
6.6
29.3
47
72
WZA90
NOMESCO Finland
Other medical or dental certificate
1.7
29.2
796
5403
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
2.7
29.0
167
651
J01CE02
ATC
phenoxymethylpenicillin; oral
1.6
28.9
1975
16593
EFB50
NOMESCO Finland
Orthodontic procedure connected with ortognathic surgery
80.7
28.7
32
*
SPAT1324
SPAT
Screening procedure
1.7
28.3
603
3828
EBA40
NOMESCO Finland
Extraction of apex of root of tooth
5.6
27.4
52
94
ZXA10
NOMESCO Finland
Bilateral
1.8
26.9
435
2547
WX704
NOMESCO Finland
Intubation
2.2
26.7
233
1095
SAALT, ,
NOMESCO Finland
3.2
26.2
105
335
ZXX03
NOMESCO Finland
Extent of procedure, 3 units
7.8
25.4
35
45
ZXE20
NOMESCO Finland
More than three and less than five hours
2.0
25.1
314
1689
F45.8
ICD-10 Finland
Other somatoform disorders
2.0
24.5
276
1430
OIKTA, ,
NOMESCO Finland
6.3
24.4
41
66
SPAT1263
SPAT
Sampling
1.5
23.3
1159
8916
ZXX07
NOMESCO Finland
Extent of procedure, 7 units
65.3
22.8
26
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
22.8
669
4581
OIKLI, ,
NOMESCO Finland
9.4
22.6
27
29
ECA55
NOMESCO Finland
Complicated periodontal flap surgery
7.9
22.1
30
38
SXB10
NOMESCO Finland
Removal of attachments and rails from moth
7.9
22.1
30
38
SDA03
NOMESCO Finland
Periodontal treatment
1.5
21.9
1132
8739
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
21.8
751
5327
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.6
21.6
686
4775
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
3.2
21.5
87
279
SCD01
NOMESCO Finland
Removal of biofilm and supragingival calculus, short
3.7
21.5
69
191
K07.9
ICD-10 Finland
Dentofacial anomaly, unspecified
43.5
21.4
26
6
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
21.2
1385
11168
SPC25
NOMESCO Finland
Other demanding attachment of prosthodontic crown
19.0
21.2
32
17
SPA02
NOMESCO Finland
Preparation for dental prosthetics
3.2
21.1
84
267
K07.68
ICD-10 Finland
Other disorders of the jaw joint
5.0
20.8
44
88
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
20.6
569
3826
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
35.9
19.8
25
7
WX725
NOMESCO Finland
Noninvasive ventilation
2.3
19.7
147
646
EBA00
NOMESCO Finland
Extraction of tooth
1.5
19.3
1090
8504
EGC30
NOMESCO Finland
Prosthetic replacement of mandibular joint
31.4
19.2
25
8
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
15.9
18.7
30
19
K01.17
ICD-10 Finland
Retained molar with obstruction in the lower jaw
2.3
18.7
148
668
EAB10
NOMESCO Finland
Excision and repair of frenum of lip
7.7
18.6
26
34
J01FF01
ATC
clindamycin; systemic
1.5
18.6
614
4291
EDW99
NOMESCO Finland
Other operation on mandible
18.8
18.6
28
15
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
18.3
189
947
K07.33
ICD-10 Finland
Crowding of tooth or teeth
5.8
18.3
33
57
K06.00
ICD-10 Finland
Local gingivore traction
3.1
18.2
74
239
WX720
NOMESCO Finland
Own respiration
2.4
18.0
128
551
SCA01
NOMESCO Finland
Preventive oral health care, short
1.4
17.9
1193
9555
R5140
NOMESCO Finland
Monitoring the use of the aid
1.9
17.8
229
1239
TEG10
NOMESCO Finland
Injection of diagnostic or therapeutic substance into mandibular joint
13.7
17.7
30
22
SCA02
NOMESCO Finland
Preventive oral health care
1.6
17.7
516
3503
N03AX16
ATC
[U] pregabalin
1.6
17.6
488
3273
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
42.1
17.3
21
5
TEG00
NOMESCO Finland
Punction of mandibular joint
17.4
16.9
26
15
K07.00
ICD-10 Finland
Macrognatia (hyperplasia) of the upper jaw
25.7
16.9
23
9
J34.2
ICD-10 Finland
Deviated nasal septum
2.2
16.6
140
649
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
7.0
16.5
25
36
M79.1
ICD-10 Finland
Myalgia
1.6
16.4
405
2638
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.4
16.4
977
7635
SPF10
NOMESCO Finland
Demanding reparation of dental prosthesis
5.6
16.4
31
56
Z50.1
ICD-10 Finland
Other physical therapy
2.3
16.3
119
519
EB1KA
NOMESCO Finland
Partial (restricted area) panoramic tomography of teeth or jaw
4.8
15.8
35
73
ECB05
NOMESCO Finland
Mucogingival remodeling
5.4
15.8
31
58
A02BC05
ATC
esomeprazole; systemic
1.4
15.7
881
6802
K07.0
ICD-10 Finland
Major anomalies of jaw size
33.4
15.7
20
6
HAMTE, ,
NOMESCO Finland
4.6
15.3
36
79
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
12.3
15.3
27
22
SPAT1301
SPAT
No procedures
1.4
15.2
758
5724
P01BA02
ATC
hydroxychloroquine; oral
1.9
14.9
192
1041
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
3.6
14.7
47
130
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
14.6
256
1522
-1, ,
NOMESCO Finland
1.4
14.5
1148
9364
SJC04, ,
NOMESCO Finland
4.9
14.5
31
63
HMAK, ,
NOMESCO Finland
1.7
14.3
303
1899
T84.62
ICD-10 Finland
Osteitis associated with dental implants
11.4
14.2
26
23
5240A
ICD-9 Finland
Dentofacial anomalies, including malocclusion, Major anomalies of jaw size
19.2
14.2
21
11
L01BA01
ATC
methotrexate; systemic
2.4
14.1
95
400
YEA05
NOMESCO Finland
Excision of gingival or connective tissue for transplantation
53.4
13.8
16
*
EGA00
NOMESCO Finland
Arthroscopy of mandibular joint
10.5
13.7
26
25
SPC01
NOMESCO Finland
Fixed dental crown
3.5
13.6
47
137
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
13.6
931
7394
OIKIN, ,
NOMESCO Finland
3.6
13.5
43
119
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.6
13.5
335
2183
4344
FHL
Osteotomy and shaping of the lower jaw (jaw deformities)
16.2
13.4
21
13
KIP00, ,
NOMESCO Finland
12.8
13.4
23
18
DJD20
NOMESCO Finland
Plastic repair of septum of nose
2.4
13.2
91
387
SPA30
NOMESCO Finland
Grinding of a single crown and bridge pillar or a single post and crown
3.6
13.2
42
116
ZXX05
NOMESCO Finland
Extent of procedure, 5 units
10.5
13.2
25
24
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
13.2
250
1520
SCD02
NOMESCO Finland
Removal of biofilm and/or supragingival calculus
4.1
13.2
35
85
ZYC01
NOMESCO Finland
Remote contact by phone
1.9
13.1
181
1003
R01AD09
ATC
mometasone; nasal
1.3
13.1
1238
10327
ECA30
NOMESCO Finland
Excision of lesion of gingiva
4.1
13.0
35
86
Z01.2
ICD-10 Finland
Dental examination
1.3
12.9
1410
12006
K03.00
ICD-10 Finland
Approximal wear
1.8
12.9
203
1171
XX2XT
NOMESCO Finland
Other injection with other radiological guidance
6.1
12.9
22
36
SPF41
NOMESCO Finland
Repair of dental crown, bridge or implant structure, standard
3.5
12.9
43
123
P01AB01
ATC
metronidazole; oral, rectal
1.4
12.8
943
7565
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.2
12.8
113
535
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
1.9
12.7
172
948
UDC00
NOMESCO Finland
Ear microscopy
1.8
12.6
194
1111
A45
ICPC
General and Unspecified, Observ/health educat/advice/diet
2.6
12.6
71
275
SJD60, ,
NOMESCO Finland
+∞
12.5
12
*
ECU00
NOMESCO Finland
Removal of implant or external fixation device from alveoli
17.3
12.5
19
11
XX3DW
NOMESCO Finland
Time consuming IT work
1.8
12.5
202
1175
K07.09
ICD-10 Finland
Anomaly in the size of the jaws UNS
24.3
12.4
17
7
K07.32
ICD-10 Finland
Displacement of tooth or teeth
5.2
12.4
25
48
XX7LW, ,
NOMESCO Finland
20.1
12.4
18
9
L04AX03
ATC
methotrexate; systemic
1.7
12.3
237
1446
A02BC03
ATC
lansoprazole; oral
1.4
12.2
528
3863
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
2.3
12.1
93
416
QA9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head or neck, unspecified
13.4
11.9
20
15
L04AB01
ATC
etanercept; parenteral
2.8
11.8
58
209
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.2
11.8
96
439
SFA00
NOMESCO Finland
Small restoration
1.5
11.7
364
2493
K05.30
ICD-10 Finland
Periodontitis complex
1.6
11.7
278
1791
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
11.6
476
3446
SPC09
NOMESCO Finland
Implant crown, demanding
22.9
11.5
16
7
SPA60
NOMESCO Finland
Fitting of intermediary dental prosthesis structures, 1 to 3 units
3.7
11.5
35
94
M01AE02
ATC
naproxen; oral, rectal
1.3
11.5
1611
14117
EEC00
NOMESCO Finland
Segmental osteotomy of maxilla
+∞
11.4
11
*
ECA50
NOMESCO Finland
Periodontal flap surgery
4.3
11.4
29
68
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
11.3
1451
12545
L88
ICPC
Rheumatoid/seropositive arthritis
2.2
11.3
94
435
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
12.7
11.1
19
15
N02BE01
ATC
paracetamol; systemic, rectal
1.4
11.0
2219
20428
SPA40
NOMESCO Finland
Precision impression for dental prosthesis
5.7
11.0
20
35
L04AA13
ATC
[U] leflunomide
2.6
11.0
63
247
SXC06
NOMESCO Finland
Clinical work to produce sleep apnoea splint
5.4
10.8
21
39
K07.35
ICD-10 Finland
Impacted or embedded teeth with abnormal position of such teeth or adjacent teeth
3.0
10.8
48
164
G50.8
ICD-10 Finland
Other disorders of trigeminal nerve
10.6
10.7
20
19
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.8
10.7
176
1029
PLAK0, ,
NOMESCO Finland
3.3
10.6
39
119
C05AA08
ATC
fluocortolone; rectal, topical
1.6
10.6
249
1599
WX402
NOMESCO Finland
General anaesthesia
1.4
10.5
522
3908
T84.60
ICD-10 Finland
Gingivitis associated with dental implants
5.0
10.5
22
44
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.4
10.4
716
5645
EDC05
NOMESCO Finland
Segmental osteotomy of mandible
+∞
10.4
10
*
Z3231
NOMESCO Finland
Registered nurse
1.4
10.4
646
5016
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
10.3
786
6294
PLAK2, ,
NOMESCO Finland
3.8
10.3
31
83
ED1AA
NOMESCO Finland
Mandibular X-ray examination
4.5
10.2
24
53
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
10.1
438
3197
ENC40
NOMESCO Finland
Uvulopalatopharyngoplasty
3.9
10.1
29
75
J02AC01
ATC
fluconazole; systemic
1.3
10.0
988
8200
SPA61
NOMESCO Finland
Fitting of intermediary dental prosthesis structures, 4 to 6 units
5.0
10.0
21
42
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.9
10.0
124
665
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
9.8
937
7734
N06AX11
ATC
mirtazapine; oral
1.3
9.8
749
5994
SFB30
NOMESCO Finland
Indirect three-surface restoration
5.1
9.8
20
39
SFB40
NOMESCO Finland
Filling of four surfaces reproduced outside mouth
4.4
9.7
24
55
C07AA05
ATC
propranolol; systemic
1.4
9.7
535
4068
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
9.7
392
2823
SPE00
NOMESCO Finland
Partial denture with metal framework
3.8
9.7
29
77
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.7
9.7
191
1174
R01AD58
ATC
fluticasone, combinations; nasal
1.3
9.7
719
5729
A07EC01
ATC
sulfasalazine; oral, rectal
1.7
9.6
175
1052
K07.08
ICD-10 Finland
Other specified anomaly in the size of the cores
55.0
9.6
11
*
EG1AD
NOMESCO Finland
CT of mandipular joint
55.0
9.6
11
*
SFA10
NOMESCO Finland
One-surface restoration
1.3
9.6
1582
14002
SPAT1153
SPAT
Removal of sutures
1.4
9.5
578
4463
SPE90
NOMESCO Finland
Other partial denture
3.3
9.5
35
107
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
1.8
9.4
133
743
AA40B, ,
NOMESCO Finland
8.0
9.3
20
25
R51.81
ICD-10 Finland
Facial pain NOS
2.4
9.3
64
274
Z01.9
ICD-10 Finland
Special examination, unspecified
1.8
9.3
126
696
N06AB10
ATC
escitalopram; oral
1.4
9.3
581
4508
SCB01
NOMESCO Finland
Instructions for self-performed oral hygiene, short
2.6
9.3
52
202
ENC30
NOMESCO Finland
Plastic operation of pharynx
3.4
9.1
32
95
A31
ICPC
General and Unspecified, Medical examin/health eval partial
1.9
9.1
112
599
R01AD12
ATC
fluticasone furoate; nasal
1.3
9.0
918
7625
EGA05
NOMESCO Finland
Rinsing of mandibular joint
15.6
9.0
14
9
EDC45
NOMESCO Finland
Reconstruction of mandible using bone graft
36.7
9.0
11
*
SPE05
NOMESCO Finland
Demanding partial denture with metal framework
9.5
8.7
17
18
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
8.7
743
6020
A78
ICPC
Infectious disease other/NOS
2.1
8.6
76
362
OIKOV, ,
NOMESCO Finland
16.3
8.5
13
8
XKC03
NOMESCO Finland
Water cystometry
2.4
8.4
57
242
KMAK, ,
NOMESCO Finland
1.3
8.4
1249
10847
K07.05
ICD-10 Finland
Micrognatia (hypoplasia) of both jaws
90.0
8.4
9
*
ZXC60
NOMESCO Finland
Application of heat
2.7
8.4
43
160
N06AX21
ATC
duloxetine; oral
1.5
8.3
271
1872
WZC30
NOMESCO Finland
Teaching
1.5
8.3
302
2132
WX199
NOMESCO Finland
Other local analgesia
2.4
8.3
55
232
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.3
8.2
527
4095
K07.6
ICD-10 Finland
Temporomandibular joint disorders
3.2
8.2
32
102
SBA00
NOMESCO Finland
Microbiological examinations
2.3
8.1
60
265
A02BA02
ATC
ranitidine; systemic
1.5
8.1
297
2097
A02BC02
ATC
pantoprazole; systemic
1.3
8.1
1430
12649
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
8.1
730
5954
POLI, ,
NOMESCO Finland
17.2
8.1
12
7
OIKSI, ,
NOMESCO Finland
6.8
8.0
19
28
K00.09
ICD-10 Finland
Lack of teeth due to lack of dental development UNS
3.3
8.0
29
88
EB1BA
NOMESCO Finland
Extensive intraoral X-ray examination
8.9
8.0
16
18
ECB10
NOMESCO Finland
Reconstruction of gingiva
10.0
8.0
15
15
EEC45
NOMESCO Finland
Reconstruction of maxilla using bone graft
22.0
8.0
11
5
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.5
8.0
258
1778
SCA04
NOMESCO Finland
Guidance on care of mouth and oral mucosa
7.7
7.8
17
22
N06AA09
ATC
amitriptyline; systemic
1.6
7.8
159
986
A02BC01
ATC
omeprazole; systemic
1.3
7.8
515
4018
EG1DG
NOMESCO Finland
Very extensive MRI examination of mandibular joint with high intensity magnet
8.4
7.8
16
19
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.5
7.8
47
190
S03.0
ICD-10 Finland
Dislocation of jaw
3.2
7.8
29
90
R03BA01
ATC
beclometasone; inhalant
1.5
7.7
268
1873
SPC50
NOMESCO Finland
Post and core abutment
15.0
7.7
12
8
K07
ICD-10 Finland
Dentofacial anomalies [including malocclusion]
3.3
7.6
27
81
L43.8
ICD-10 Finland
Other lichen planus
3.0
7.6
33
112
SPAT1260
SPAT
Consultation of another employee
1.4
7.6
378
2822
D19
ICPC
Teeth/gum symptom/complaint
1.3
7.6
799
6639
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.7
7.5
145
888
J01DB01
ATC
cefalexin; oral
1.3
7.5
2188
20432
G43.9
ICD-10 Finland
Migraine, unspecified
1.5
7.5
204
1356
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
7.4
933
7916
UDM02
NOMESCO Finland
Sinoscopy
2.3
7.4
52
226
SPAT1240
SPAT
Therapeutic discussion
1.4
7.3
340
2508
L04AB06
ATC
golimumab; parenteral
3.0
7.3
31
104
EG1DM
NOMESCO Finland
Mandibular joint very extensive MRI examination with 3 Tesla magnet
+∞
7.3
7
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.5
7.3
209
1406
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.5
7.2
252
1763
SPC30
NOMESCO Finland
Surface-retained bridge
3.8
7.2
21
55
SPA05
NOMESCO Finland
Surgical guide
15.7
7.2
11
7
DHB50
NOMESCO Finland
Turbinoplasty
2.0
7.2
72
360
SPAT1044
SPAT
Tympanometry
2.0
7.2
73
367
RD211, ,
NOMESCO Finland
1.9
7.2
87
465
A03FA02
ATC
cisapride; oral, rectal
1.7
7.1
122
723
H02AB06
ATC
prednisolone; systemic
1.2
7.1
997
8552
H02.3
ICD-10 Finland
Blepharochalasis
1.9
7.1
92
502
K05.11
ICD-10 Finland
Gingivitis (chronic) hyperplastic
4.2
7.0
18
43
M03BX02
ATC
tizanidine; oral
1.2
6.9
1442
12900
J02AC02
ATC
itraconazole; systemic
1.4
6.9
346
2584
K07.2
ICD-10 Finland
Anomalies of dental arch relationship
13.8
6.9
11
8
SPAT1130
SPAT
Esophagoscopy, gastroscopy and duodenoscopy
2.2
6.9
54
246
M01AC06
ATC
meloxicam; systemic, rectal
1.3
6.9
672
5523
SPB06
NOMESCO Finland
Production of temporary clinic-made tooth- or implant-retained crown or bridge unit
3.6
6.8
22
62
A30
ICPC
General and Unspecified, Medical examin/health eval complete
1.9
6.8
76
396
N06AB05
ATC
paroxetine; oral
1.6
6.8
136
842
N02BF02
ATC
pregabalin; oral
1.7
6.8
118
704
EEW99
NOMESCO Finland
Other operation on maxilla
40.0
6.7
8
*
RF211, ,
NOMESCO Finland
5.6
6.7
18
32
SPE02
NOMESCO Finland
Metal-framed partial denture
2.9
6.7
30
104
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.6
6.7
149
947
TUPEI, ,
NOMESCO Finland
1.7
6.7
118
707
SCB02
NOMESCO Finland
Instructions for self-performed oral hygiene
3.4
6.7
23
68
J34.3
ICD-10 Finland
Hypertrophy of nasal turbinates
2.1
6.6
58
276
WX723
NOMESCO Finland
CPAP therapy
1.9
6.6
83
449
N03AX12
ATC
[U] gabapentin; oral
1.4
6.6
301
2212
R03AC02
ATC
salbutamol; inhalant
1.2
6.6
1417
12694
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.5
6.5
170
1120
SPAT1193
SPAT
Pap smear
1.4
6.5
268
1934
L07
ICPC
Jaw symptom/complaint
2.1
6.5
55
258
7143C
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Juvenile chronic polyarthritis[POLYARTHRITIS JUVENILIS SERONEGATIVA]
10.0
6.5
12
12
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
2.4
6.5
44
188
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.3
6.5
422
3280
M50.3
ICD-10 Finland
Other cervical disc degeneration
2.3
6.5
46
201
K07.55
ICD-10 Finland
Malocclusion caused by tongue, lip and finger habits
6.2
6.4
16
26
SPF50
NOMESCO Finland
Removal and reattachment of bridge
5.7
6.4
17
30
EFW99
NOMESCO Finland
Other operation on jaws
69.8
6.4
7
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.3
6.4
380
2913
XA420
NOMESCO Finland
Extensive sleep examination
3.1
6.4
25
80
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
2.5
6.4
38
153
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
1.8
6.4
82
448
S82
ICPC
Naevus/mole
1.4
6.4
304
2253
Z16
ICPC
Relationship problem with child
4.1
6.3
17
42
K12.2
ICD-10 Finland
Cellulitis and abscess of mouth
2.7
6.3
32
119
SPAT1051
SPAT
Guidance regarding sleep disorders
2.3
6.3
44
191
SPAT1097
SPAT
Recording of ECG
1.5
6.3
216
1508
VALMI, ,
NOMESCO Finland
1.2
6.3
822
6977
HAHOM, ,
NOMESCO Finland
2.4
6.3
42
179
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
6.2
593
4848
POLMA, ,
NOMESCO Finland
+∞
6.2
6
*
XX3GW
NOMESCO Finland
3D printout, very extensive
+∞
6.2
6
*
SJC05
NOMESCO Finland
Bracket with demanding fixed attachment
+∞
6.2
6
*
K01.16
ICD-10 Finland
Retained molar with obstruction in the upper jaw
2.0
6.2
60
297
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.7
6.2
116
706
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.5
6.2
183
1240
ECA00
NOMESCO Finland
Surgical exposure of tooth
2.8
6.2
30
109
WX110
NOMESCO Finland
Infiltration anesthesia
1.2
6.2
1973
18346
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.7
6.2
106
631
L04AB04
ATC
adalimumab; parenteral
2.0
6.1
65
333
AA3AD
NOMESCO Finland
CT of face
3.4
6.1
21
62
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
6.1
777
6575
K03.30
ICD-10 Finland
Internal granuloma of pulp
4.1
6.1
16
39
K03.66
ICD-10 Finland
Tooth plaque
1.4
6.1
220
1553
KHV, ,
NOMESCO Finland
3.6
6.0
19
53

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
912
6216
1.68
33.84
3.4
2.7
—
—
—
0
0
115
344
3.43
31.77
4.5
3.3
—
—
—
0
0
1357
10868
1.47
21.76
3.7
3.1
0.01
0.00
estimate
0.42
327
2150
1357
10949
1.45
20.46
3.7
3.1
0.00
0.00
estimate
0.05
298
2043
1346
10863
1.45
20.15
5.2
4.3
0.00
0.00
estimate
0.40
311
2110
272
1580
1.79
16.89
4.6
4.6
0.00
0.53
%
1.07
45
385
281
1658
1.77
16.54
4.5
4.5
0.19
0.11
%
0.38
56
470
272
1611
1.76
15.79
4.3
4.2
0.66
0.63
%
0.08
55
483
288
1734
1.73
15.77
4.5
4.4
0.79
0.91
%
0.27
62
548
128
587
2.23
15.59
3.7
6.9
0.90
0.92
%
0.25
118
549
127
591
2.20
14.93
3.7
6.8
1.38
1.65
%
3.74
116
551
504
3551
1.50
14.31
1.6
1.5
59410872.99
35804896.80
pmol/l
0.25
441
3089
1096
8933
1.36
13.64
3.2
2.9
5.95
5.92
ph
0.13
105
875
48
147
3.29
12.92
1.8
2.3
—
—
—
0
0
156
840
1.90
12.35
4.8
2.5
—
—
—
0
0
134
714
1.91
10.97
2.7
3.9
25.43
25.29
mmol/l
0.25
129
685
156
874
1.82
10.92
3.4
2.8
0.25
0.23
e6/l
0.05
149
842
1818
16293
1.31
10.50
4.5
3.9
8.47
9.42
mm/h
4.09
1724
15223
1695
15140
1.29
9.55
4.8
3.8
—
—
—
0
0
714
5714
1.33
9.25
3.8
3.4
0.00
0.00
estimate
0.01
305
2056
218
1401
1.60
9.25
3.3
3.6
1.23
1.23
mmol/l
0.63
197
1229
1324
11513
1.27
9.05
3.1
2.9
75.58
84.85
ug/l
1.06
1260
10876
1178
10098
1.28
9.04
2.5
2.5
—
—
—
0
0
163
981
1.70
8.95
3.0
4.1
135.98
131.41
g/l
2.18
158
955
2026
18598
1.30
8.83
4.3
3.9
14.49
14.42
pmol/l
0.71
1880
17214
1212
10487
1.27
8.42
9.7
8.6
0.00
0.00
e9/l
0.48
1058
8562
98
522
1.90
8.11
3.8
7.6
1.21
1.21
mmol/l
0.02
86
456
760
6258
1.29
7.77
2.4
2.6
90.21
57.67
u/l
0.55
710
5844
2256
21148
1.31
7.54
14.0
13.0
13.76
14.16
%
5.25
2214
20755
154
963
1.63
7.35
1.3
1.3
0.38
1.02
u/ml
—
6
80
230
1585
1.49
7.13
2.7
2.1
13.14
11.39
nmol/l
2.28
211
1446
2278
21443
1.30
6.96
4.9
4.5
1.77
1.95
mu/l
1.18
2157
20222
885
7507
1.25
6.94
7.5
8.5
1.11
1.13
inr
0.52
316
2403
1286
11365
1.23
6.93
6.7
6.2
54.67
55.30
%
1.38
1237
10752
2573
24672
1.42
6.86
11.0
9.7
—
—
—
0
0
1300
11520
1.23
6.77
6.9
6.4
31.21
30.32
%
2.67
1255
10909
1728
15804
1.23
6.53
6.5
6.8
75.93
78.53
u/l
1.69
1660
14979
344
2591
1.37
6.51
1.6
1.6
1247.72
1173.87
nmol/l
0.90
278
2033
266
1919
1.42
6.49
1.4
1.3
159.42
237.15
u/ml
1.91
251
1783
694
5766
1.26
6.42
2.8
2.4
—
—
—
0
0
1006
8733
1.23
6.23
2.8
2.4
—
—
—
0
0
1235
11000
1.21
5.80
7.0
6.4
2.94
2.85
%
0.65
1186
10359
1350
12130
1.21
5.78
7.0
6.3
1.95
2.01
e9/l
0.84
1273
10867
1243
11081
1.21
5.78
7.3
6.7
8.25
8.19
%
0.30
1192
10455
1234
11005
1.21
5.68
7.7
6.7
—
—
—
0
0
227
1642
1.41
5.48
2.9
3.3
4.72
4.64
pmol/l
0.40
207
1481
1190
10612
1.20
5.39
7.1
6.5
0.69
0.67
%
0.70
1141
9964
1342
12103
1.20
5.38
7.2
6.6
0.18
0.19
e9/l
0.24
1255
10756
431
5279
0.78
5.23
4.6
4.1
95.50
94.67
%
0.33
420
5153
485
5837
0.79
5.06
7.2
6.9
—
—
—
0
0
1054
9337
1.20
5.03
6.9
6.8
1.22
1.22
mmol/l
0.75
895
8069
572
4769
1.25
5.00
3.1
3.0
—
—
—
0
0
1295
11702
1.19
4.92
7.0
6.3
0.54
0.54
e9/l
0.46
1206
10238
1295
11713
1.19
4.84
7.0
6.3
0.04
0.04
e9/l
0.06
1201
10233
2369
22651
1.26
4.83
11.0
11.3
3.91
3.92
mmol/l
1.12
2303
22006
78
460
1.71
4.77
3.0
3.7
3.44
3.90
e9/l
1.31
78
460
729
6269
1.21
4.71
2.6
2.8
25.57
45.95
ng/l
1.33
349
3218
130
876
1.50
4.59
1.0
1.1
9.07
4.28
u/ml
0.43
15
127
42
206
2.05
4.54
2.1
1.6
32.79
54.84
%
2.61
28
134
61
340
1.81
4.54
4.9
9.8
10.94
11.39
mmol/l
0.51
52
307
469
3865
1.25
4.53
3.4
2.8
567.55
555.38
mosm/kgh2o
0.43
411
3339
61
341
1.80
4.50
4.9
9.8
106.15
105.58
mmol/l
0.43
52
308
78
469
1.68
4.46
3.6
3.9
51.15
55.42
%
2.39
78
469
779
6788
1.20
4.33
1.4
1.4
1.41
1.63
u/ml
0.24
245
1757
254
1950
1.33
4.26
3.8
3.4
—
—
—
0
0
69
410
1.69
4.15
3.4
3.0
22.18
22.82
mg/l
0.05
49
255
486
4070
1.23
4.03
1.3
1.3
20.40
26.02
iu/ml
0.86
152
1259
1291
11795
1.17
4.00
4.0
4.6
6.18
6.39
mmol/l
3.54
1169
10888
2352
22580
1.22
3.96
11.1
11.2
139.79
139.65
mmol/l
2.75
2292
21991
121
835
1.46
3.85
2.4
2.2
—
—
—
0
0
439
3661
1.23
3.79
2.5
2.7
115.73
111.45
ug/g
0.11
357
2913
31
146
2.13
3.77
1.0
1.1
428.68
400.19
nmol/l
0.35
25
139
155
2089
0.72
3.73
3.4
3.6
30.37
32.07
%
1.27
115
1546
148
1068
1.40
3.71
2.5
2.9
76.83
132.58
ng/l
2.89
135
943
2430
23447
1.23
3.66
11.2
10.8
17.79
20.61
mg/l
4.24
1873
17572
338
2751
1.26
3.63
1.8
1.9
—
—
—
0
0
335
2728
1.25
3.59
2.4
2.4
2.55
2.47
g/l
2.14
310
2548
288
2304
1.27
3.58
2.2
2.2
354.77
374.84
nmol/l
0.99
271
2142
601
5217
1.19
3.40
2.1
2.3
2.75
2.74
mg/l
0.03
543
4533
453
3839
1.21
3.33
1.2
1.3
11.82
9.37
u/ml
0.33
212
1578
1528
14268
1.15
3.24
4.4
3.7
902.59
762.76
e6/l
0.11
27
154
9
19
4.73
3.23
6.8
5.3
—
—
—
0
0
362
3009
1.23
3.22
2.5
2.4
15.62
14.40
umol/l
2.24
341
2826
31
157
1.98
3.16
1.3
1.4
201.84
233.96
pmol/l
0.22
31
157
403
3397
1.21
3.13
1.4
1.4
514.02
536.12
titre
0.09
87
660
1095
10011
1.15
3.13
5.2
5.9
10.16
10.48
umol/l
0.69
1045
9469
149
1955
0.75
3.04
2.3
2.4
36.55
61.19
u/l
0.49
126
1683
1488
13913
1.14
2.99
3.0
2.9
—
—
—
0
0
181
1398
1.31
2.98
1.2
1.2
—
—
—
0
0
1000
9109
1.15
2.98
2.7
2.4
77.62
72.86
nmol/l
5.82
947
8475
52
316
1.65
2.97
1.8
1.6
—
—
—
0
0
873
7883
1.15
2.94
4.9
5.1
37.13
36.95
g/l
0.50
827
7401
108
775
1.40
2.87
1.4
1.8
0.23
0.23
g/l
0.06
101
734
556
4864
1.17
2.84
3.3
3.2
1.02
1.02
kg/l
0.54
73
703
268
2196
1.24
2.75
1.2
1.2
84.45
156.57
iu/ml
3.76
99
832
833
7529
1.15
2.74
3.7
3.3
29.31
30.71
u/l
0.60
799
7189
37
211
1.76
2.68
1.0
1.0
—
—
—
0
0
119
880
1.36
2.66
6.6
8.3
24.34
24.45
mmol/l
0.12
110
834
126
1654
0.75
2.62
2.3
3.7
—
—
—
0
0
17
74
2.30
2.56
1.8
2.5
—
—
—
0
0
109
801
1.37
2.55
1.4
1.7
1.17
1.18
g/l
0.16
102
758
440
3811
1.18
2.54
1.4
1.5
21.24
20.29
nmol/l
0.79
400
3390
12
44
2.73
2.53
1.2
1.1
—
—
—
0
0
12
44
2.73
2.53
1.2
1.1
—
—
—
0
0
12
44
2.73
2.53
1.2
1.1
—
—
—
0
0
398
3423
1.19
2.50
4.3
3.9
1.67
1.87
ug/l
0.67
370
3126
24
122
1.97
2.48
3.9
2.1
1.22
2.29
u/field
—
9
73
7
192
0.36
2.39
1.3
1.2
—
—
—
0
0
27
146
1.85
2.35
2.2
1.6
60.73
35.41
%
2.36
19
92
69
475
1.46
2.35
1.1
1.1
—
—
—
0
0
479
4204
1.16
2.35
1.5
1.5
—
—
—
0
0
36
216
1.67
2.23
1.3
1.3
0.33
2.74
u/ml
2.51
20
109
1407
13256
1.12
2.23
9.3
8.9
3.69
3.87
e9/l
2.90
1295
11578
57
827
0.68
2.21
8.3
11.3
23.80
24.27
mmol/l
0.69
52
815
692
6264
1.13
2.17
2.8
3.1
2.36
2.36
mmol/l
0.00
650
5695
200
1635
1.24
2.15
1.2
1.2
121.67
211.43
titre
—
6
42
14
61
2.29
2.13
1.2
1.4
—
—
—
0
0
206
1695
1.23
2.09
7.1
4.9
4.74
4.82
kpa
0.27
200
1639
1672
15936
1.11
2.07
3.1
3.1
38.71
38.76
u/l
0.01
1594
15227
5
10
4.99
2.06
4.6
2.6
4.40
4.17
mmol/l
—
5
10
104
789
1.33
2.04
1.2
1.2
—
—
—
0
0
260
2196
1.20
2.03
1.3
1.4
—
—
—
0
0
7
177
0.39
2.02
1.3
1.4
1.25
1.43
nmol/l
—
7
165
36
223
1.62
2.00
2.5
2.6
75.47
73.19
%
0.34
36
216
188
1541
1.23
1.99
1.5
1.6
295.19
316.38
mu/l
0.44
169
1390
368
3212
1.16
1.95
2.9
3.2
194.10
550.65
ng/l
3.32
201
1930
405
3561
1.16
1.95
2.6
3.0
442.27
709.81
ng/l
2.71
326
2903
312
2690
1.18
1.93
1.2
1.2
—
—
—
0
0
79
584
1.36
1.86
2.6
2.6
6.24
5.38
umol/l
0.29
55
448
287
2468
1.18
1.85
1.6
1.5
—
—
—
0
0
35
221
1.59
1.83
2.6
2.6
10.49
12.63
%
1.08
35
216
148
1807
0.81
1.80
11.1
9.3
—
—
—
0
0
2712
26724
1.26
1.80
17.0
15.7
260.65
261.68
e9/l
0.40
2666
26060
290
2502
1.17
1.80
2.5
2.5
26.19
23.85
%
1.62
242
2188
73
537
1.36
1.78
1.3
1.2
22.60
40.33
u/ml
—
7
51
2714
26752
1.25
1.75
17.0
15.7
6.52
6.65
e9/l
2.10
2668
26030
2713
26742
1.25
1.74
16.9
15.7
89.76
89.68
fl
0.41
2689
26413
68
497
1.37
1.74
1.1
1.1
2.53
3.34
u/ml
0.38
42
235
291
2521
1.17
1.72
1.6
1.6
—
—
—
0
0
569
5163
1.12
1.71
2.1
2.1
146.63
202.89
u/l
1.80
534
4915
2713
26746
1.25
1.70
16.9
15.6
30.01
29.97
pg
0.57
2689
26418
2713
26750
1.25
1.67
17.0
15.7
4.57
4.56
e12/l
0.40
2664
26041
181
1509
1.21
1.67
1.2
1.2
—
—
—
0
0
2708
26702
1.24
1.62
17.0
15.8
40.27
40.63
%
1.00
2505
25342
2713
26761
1.24
1.58
17.1
15.8
136.58
136.13
g/l
1.08
2689
26437
15
77
1.95
1.58
2.2
1.4
2.40
9.00
%
—
5
17
51
362
1.41
1.57
4.1
3.6
—
—
—
0
0
0
43
0.00
1.52
0.0
2.3
—
—
—
0
0
0
43
0.00
1.52
0.0
1.2
—
—
—
0
0
2220
21616
1.11
1.51
14.2
13.3
333.66
333.31
g/l
1.08
2200
21425
537
4898
1.11
1.48
2.0
2.0
0.82
0.96
mg/l
0.65
392
3589
14
72
1.94
1.47
1.4
1.9
—
—
—
0
0
72
549
1.32
1.44
1.4
1.4
283.44
309.90
ug/g
0.49
35
287
14
73
1.92
1.42
2.3
2.7
—
—
—
0
0
164
1380
1.20
1.41
1.4
1.4
—
—
—
0
0
86
675
1.28
1.40
1.3
1.2
10.54
37.19
u/ml
—
8
41
180
1530
1.18
1.38
1.4
1.4
—
—
—
0
0
2482
24350
1.13
1.36
9.6
8.8
26.34
26.33
u/l
0.00
2413
23658
636
5881
1.10
1.35
1.5
1.5
2.01
2.09
g/l
0.91
449
3633
225
1953
1.16
1.34
6.9
5.3
5.75
5.90
kpa
1.89
217
1890
17
97
1.75
1.33
1.3
1.6
16.44
13.84
pmol/l
1.49
17
81
234
2039
1.16
1.33
2.7
2.2
6145.89
6412.42
u/l
0.05
89
745
29
191
1.52
1.33
2.0
2.1
32.93
32.21
pg
0.33
29
191
223
1937
1.16
1.32
6.9
5.3
1.58
1.82
mmol/l
0.63
191
1600
12
61
1.97
1.31
2.4
3.0
—
—
—
0
0
9
43
2.09
1.29
2.2
1.0
—
—
—
0
0
135
1126
1.21
1.29
1.4
1.3
—
—
—
0
0
79
621
1.28
1.29
1.4
1.3
4.07
12.33
u/ml
—
10
106
397
3591
1.12
1.28
1.7
1.6
—
—
—
0
0
78
613
1.28
1.28
1.3
1.2
3.41
7.12
u/ml
—
8
69
5
19
2.63
1.21
3.6
1.6
127.80
93.32
ng/l
—
5
19
55
417
1.32
1.19
3.0
4.0
1.80
2.19
mmol/l
0.79
36
264
793
7447
1.09
1.19
1.7
1.6
—
—
—
0
0
281
3127
0.88
1.18
3.4
2.8
3.09
3.57
e6/l
0.37
175
1637
20
309
0.64
1.17
2.1
2.9
2.68
56.64
u/ml
0.76
20
304
233
2057
1.14
1.13
2.7
2.6
0.65
0.69
ug/l
0.30
115
1169
5
110
0.45
1.13
2.6
2.1
226.60
149.46
nmol/l
—
5
94
40
292
1.37
1.12
8.2
2.9
—
—
—
0
0
144
1228
1.18
1.11
1.3
1.3
203.47
222.79
miu/ml
0.30
71
598
40
536
0.74
1.10
2.6
2.1
—
—
—
0
0
48
362
1.33
1.09
2.9
2.5
17.43
17.16
%
0.20
26
188
298
3286
0.89
1.09
3.2
2.6
0.96
1.16
e6/l
0.32
194
1791
25
168
1.49
1.08
1.9
1.9
—
—
—
0
0
16
254
0.63
1.07
2.8
3.9
15.25
1210.08
u/ml
0.67
11
238
748
7036
1.08
1.07
1.8
1.7
97.72
97.74
pmol/l
0.00
393
3814
52
667
0.77
1.06
1.3
1.2
—
—
—
0
0
6
121
0.49
1.05
1.2
1.1
110.92
231.27
iu/ml
—
6
121
515
5512
0.92
1.04
3.4
2.9
—
—
—
0
0
588
5489
1.09
1.02
1.7
1.7
—
—
—
0
0
56
439
1.28
0.99
2.4
2.3
132.83
133.76
g/l
0.14
48
340
152
1317
1.16
0.99
2.8
2.2
—
—
—
0
0
102
855
1.20
0.98
6.6
12.2
—
—
—
0
0
36
265
1.36
0.98
2.9
3.3
1.56
1.25
%
0.24
31
246
442
4084
1.09
0.97
3.0
2.6
6.40
7.54
e6/l
0.90
399
3651
0
31
0.00
0.96
0.0
1.3
—
52.69
—
0
26
12
198
0.60
0.96
12.5
12.6
634.75
821.98
nmol/l
1.11
12
190
211
1876
1.13
0.95
1.4
1.5
25.46
23.76
iu/l
0.33
185
1561
51
645
0.78
0.95
1.4
1.5
0.36
0.38
nmol/l
0.11
37
517
36
267
1.35
0.94
1.0
1.1
0.58
3.10
u/ml
1.60
12
121
6
118
0.51
0.93
1.3
1.2
—
—
—
0
0
2106
20602
1.07
0.93
3.7
3.6
5.63
5.68
mmol/l
1.45
1980
19232
138
1580
0.86
0.93
1.6
1.4
—
—
—
0
0
136
1176
1.16
0.92
1.5
1.7
8.46
8.59
u/l
0.04
106
950
24
167
1.44
0.90
2.1
1.6
7.29
6.24
mmol/l
0.49
18
126
13
78
1.66
0.90
2.6
2.2
15.19
18.05
umol/l
0.40
13
78
59
727
0.81
0.90
1.4
1.2
—
—
—
0
0
466
4970
0.92
0.88
2.4
2.2
—
—
—
0
0
53
421
1.26
0.87
3.8
3.7
—
—
—
0
0
105
897
1.17
0.85
4.8
6.1
—
—
—
0
0
48
598
0.80
0.82
1.1
1.3
—
—
—
0
0
11
65
1.69
0.81
1.1
1.2
—
—
—
0
0
6
32
1.87
0.81
1.3
1.2
—
—
—
0
0
35
267
1.31
0.79
2.8
1.6
97.12
43.49
mu/l
0.94
35
244
466
4361
1.08
0.78
1.7
1.7
—
—
—
0
0
0
27
0.00
0.77
0.0
1.2
—
1.77
—
0
27
5
100
0.50
0.77
1.2
1.1
—
—
—
0
0
731
6956
1.06
0.76
2.0
2.0
—
—
—
0
0
74
621
1.19
0.75
2.0
1.6
112.67
102.74
u/ml
0.73
18
102
28
369
0.75
0.75
4.7
5.5
429.39
383.68
umol/l
0.78
23
327
97
1117
0.86
0.74
11.2
4.7
—
—
—
0
0
32
244
1.31
0.74
1.1
1.1
210.78
236.16
mg/l
0.47
27
217
82
956
0.85
0.74
1.8
1.7
—
—
—
0
0
39
306
1.27
0.73
1.1
1.3
—
—
—
0
0
496
4665
1.07
0.73
3.8
3.9
6.87
9.15
mg/mmol
0.71
327
3072
102
1168
0.87
0.73
1.9
2.0
4.92
6.93
ug/l
1.37
95
1044
45
361
1.25
0.71
1.5
1.6
—
—
—
0
0
22
297
0.74
0.70
3.5
2.2
—
—
—
0
0
562
5318
1.07
0.70
1.7
1.6
1.33
1.38
mmol/l
0.85
482
4649
140
1563
0.89
0.70
13.9
8.6
24.63
24.93
mmol/l
0.45
140
1558
77
656
1.17
0.68
1.9
2.0
3.05
4.87
iu/l
2.63
28
253
91
787
1.16
0.67
15.0
9.6
1.17
1.24
mg/l
0.81
85
757
68
574
1.19
0.67
1.1
1.1
7.68
6.98
u/ml
0.09
40
266
105
918
1.15
0.67
1.2
1.1
1.34
3.25
u/ml
1.96
62
519
7
44
1.59
0.65
1.1
1.0
—
—
—
0
0
23
171
1.34
0.64
1.2
1.1
—
—
—
0
0
12
177
0.67
0.64
1.1
1.1
—
—
—
0
0
5
29
1.72
0.63
1.0
1.3
—
—
—
0
0
5
29
1.72
0.63
1.0
1.1
—
—
—
0
0
34
269
1.26
0.62
1.4
1.4
2.73
2.85
g/l
0.18
25
190
34
269
1.26
0.62
1.4
1.4
0.35
0.38
g/l
0.19
25
189
18
245
0.73
0.62
1.2
1.2
—
—
—
0
0
13
87
1.49
0.62
1.8
2.5
—
—
—
0
0
24
181
1.32
0.62
1.3
1.6
—
—
—
0
0
20
267
0.74
0.61
1.1
1.3
—
—
—
0
0
5
30
1.66
0.61
3.6
2.1
—
—
—
0
0
29
367
0.79
0.61
2.4
2.5
—
—
—
0
0
34
270
1.26
0.61
1.4
1.4
6.22
6.30
g/l
0.06
25
191
91
795
1.15
0.60
1.1
1.1
2.02
2.82
u/ml
0.37
56
461
0
20
0.00
0.60
0.0
2.1
—
19.32
—
0
20
10
151
0.66
0.60
1.3
1.3
—
—
—
0
0
46
379
1.21
0.60
3.4
3.2
20.86
25.12
nmol/l
1.67
46
370
32
254
1.26
0.58
1.1
1.2
38.40
39.84
mg/l
0.07
25
213
6
35
1.71
0.57
2.0
1.9
—
—
—
0
0
27
341
0.79
0.57
1.2
1.3
—
—
—
0
0
8
54
1.48
0.57
1.0
1.1
—
—
—
0
0
12
172
0.69
0.57
2.2
1.5
—
—
—
0
0
14
195
0.71
0.56
6.8
3.3
—
—
—
0
0
75
650
1.15
0.56
2.0
1.5
—
—
—
0
0
141
1549
0.90
0.56
5.3
8.1
1.24
1.29
mmol/l
0.43
135
1516
202
1858
1.09
0.56
3.2
2.8
9.92
10.34
g/l
0.95
188
1730
34
274
1.24
0.55
1.4
1.4
—
—
—
0
0
86
755
1.14
0.55
5.4
4.6
0.22
0.39
g/l
1.27
49
386
49
577
0.84
0.54
2.1
1.8
74.12
1179.73
e6/l
1.50
41
468
14
193
0.72
0.54
2.9
2.1
—
—
—
0
0
247
2639
0.93
0.54
8.7
7.0
1.09
1.10
mmol/l
0.19
232
2496
49
576
0.85
0.53
2.1
1.7
2.12
18.64
e6/l
3.02
41
445
147
1336
1.10
0.53
3.8
3.3
67.18
71.58
e9/l
0.82
115
973
43
511
0.84
0.53
1.2
1.2
—
—
—
0
0
72
627
1.15
0.52
1.1
1.1
14.58
4.34
u/ml
0.86
49
326
6
40
1.50
0.51
2.3
1.8
—
—
—
0
0
21
161
1.30
0.50
3.4
3.1
17.24
12.11
%
0.50
21
155
17
224
0.76
0.50
1.4
1.6
—
—
—
0
0
14
189
0.74
0.49
1.4
1.2
—
—
—
0
0
7
45
1.55
0.48
1.0
1.0
—
—
—
0
0
214
2286
0.93
0.48
1.6
1.5
—
—
—
0
0
10
143
0.70
0.48
1.5
2.7
—
—
—
0
0
175
1884
0.92
0.48
2.6
3.0
0.23
0.23
g/l
0.52
165
1782
127
1385
0.91
0.46
4.1
4.1
14.85
17.75
ug/l
0.12
100
1046
19
146
1.30
0.46
1.2
1.2
—
—
—
0
0
19
146
1.30
0.46
1.3
1.3
71.47
73.30
umol/l
0.23
19
146
19
146
1.30
0.46
1.1
1.1
2331.74
1469.53
miu/ml
2.03
19
146
59
513
1.15
0.45
1.6
2.4
0.68
0.78
nmol/l
0.67
50
436
26
209
1.24
0.45
1.2
1.1
—
—
—
0
0
2060
20302
1.04
0.44
3.5
3.4
1.24
1.26
mmol/l
0.75
1960
19188
227
2408
0.93
0.43
3.8
3.2
6.68
6.89
umol/l
0.04
194
2071
327
3098
1.06
0.43
1.3
1.3
—
—
—
0
0
15
196
0.76
0.43
1.7
1.5
—
—
—
0
0
1896
18660
1.04
0.43
4.7
4.4
37.74
38.11
mmol/mol
0.60
1798
17650
531
5495
0.95
0.43
3.5
3.0
0.23
0.33
e6/l
0.98
430
4095
12
162
0.74
0.43
5.7
3.5
—
—
—
0
0
172
1595
1.08
0.43
1.9
2.5
3.81
5.40
e9/l
2.51
155
1398
2150
21216
1.04
0.42
3.9
3.7
4.77
4.75
mmol/l
0.49
2050
20203
266
2507
1.06
0.42
1.2
1.2
—
—
—
0
0
6
91
0.66
0.42
1.0
1.5
—
—
—
0
0
13
172
0.75
0.41
1.5
1.2
—
—
—
0
0
22
271
0.81
0.41
1.8
1.8
—
—
—
0
0
0
16
0.00
0.41
0.0
1.5
—
—
—
0
0
601
5794
1.04
0.41
3.0
3.4
8.36
8.23
mmol/l
0.24
540
5125
0
17
0.00
0.40
0.0
1.0
—
0.08
—
0
12
89
979
0.90
0.40
1.5
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
135
1453
0.92
0.39
9.6
4.4
7.41
7.41
ph
0.02
16
150
19
150
1.26
0.39
3.2
2.6
28.79
28.77
%
0.00
19
145
22
178
1.23
0.38
1.2
1.2
—
—
—
0
0
56
629
0.89
0.37
1.4
2.2
1.21
1.41
g/l
1.30
49
560
46
523
0.87
0.37
1.0
1.1
0.06
0.38
u/ml
3.08
11
164
16
125
1.28
0.36
2.1
2.5
498.00
593.07
ml
—
9
85
109
1178
0.92
0.36
1.4
1.4
—
—
—
0
0
5
79
0.63
0.35
1.0
1.1
—
18.67
%
—
0
6
15
117
1.28
0.34
2.5
1.9
—
—
—
0
0
17
135
1.26
0.34
1.0
1.1
—
—
—
0
0
298
2842
1.05
0.34
2.8
2.7
28.64
29.68
s
3.68
284
2760
27
227
1.19
0.33
3.0
4.1
—
—
—
0
0
127
1179
1.08
0.33
1.1
1.1
—
—
—
0
0
18
220
0.81
0.33
4.0
3.7
—
—
—
0
0
47
416
1.13
0.31
1.4
1.7
0.55
0.75
g/l
1.11
30
320
129
1202
1.07
0.31
2.4
2.5
26.03
39.43
u/ml
1.21
122
1166
154
1631
0.94
0.31
11.9
9.3
6.77
7.24
mmol/l
0.51
149
1575
158
1483
1.07
0.31
1.6
1.4
—
—
—
0
0
31
266
1.16
0.31
1.0
1.1
0.76
5.14
u/ml
—
10
102
11
142
0.77
0.31
8.3
3.9
—
—
—
0
0
138
1466
0.94
0.31
3.1
3.2
—
—
—
0
0
198
1874
1.06
0.30
4.6
3.8
1.63
1.67
%
0.24
183
1710
114
1059
1.08
0.30
1.1
1.1
—
—
—
0
0
23
271
0.84
0.30
1.6
1.5
—
—
—
0
0
22
184
1.19
0.29
1.3
1.5
0.93
0.95
g/l
0.12
22
184
11
84
1.31
0.29
1.8
1.8
—
—
—
0
0
13
102
1.27
0.29
1.0
1.1
0.38
7.83
u/ml
0.68
13
91
2130
21074
1.03
0.28
3.9
3.6
1.49
1.48
mmol/l
1.07
2027
19987
39
438
0.89
0.28
1.5
1.8
—
—
—
0
0
51
458
1.11
0.28
1.2
1.1
—
—
—
0
0
29
251
1.15
0.27
3.7
4.1
28.63
130.79
u/ml
—
7
72
22
257
0.85
0.27
1.1
1.1
3.14
8.86
iu/ml
—
7
56
21
177
1.18
0.26
1.2
1.2
1.09
1.04
ratio
—
6
75
89
953
0.93
0.26
1.4
1.5
—
—
—
0
0
25
288
0.86
0.26
1.1
1.3
—
0.41
nmol/l
—
0
9
5
72
0.69
0.26
1.6
1.2
—
—
—
0
0
12
95
1.26
0.25
1.2
4.6
80.42
79.70
mg/l
0.02
12
73
88
941
0.93
0.25
1.8
1.7
—
—
—
0
0
65
704
0.92
0.25
1.1
1.1
—
—
—
0
0
35
392
0.89
0.25
4.6
4.4
—
—
—
0
0
76
817
0.93
0.25
1.1
1.1
0.33
1.46
u/ml
3.70
35
410
203
1937
1.05
0.25
1.6
2.0
—
—
—
0
0
158
1499
1.05
0.24
6.4
9.7
96.36
96.25
%
0.08
143
1451
89
949
0.93
0.24
1.4
1.4
—
—
—
0
0
49
536
0.91
0.24
2.3
2.1
4.41
2.03
ug/l
0.48
42
489
12
147
0.81
0.24
2.8
3.1
42.37
46.35
mg/l
—
7
106
6
85
0.70
0.24
1.7
1.7
—
—
—
0
0
149
1413
1.05
0.24
6.5
10.0
124.71
123.54
g/l
0.34
140
1377
10
125
0.80
0.23
1.6
2.1
—
—
—
0
0
2157
21372
1.03
0.22
4.1
3.9
2.87
2.86
mmol/l
0.15
2054
20223
459
4464
1.03
0.22
2.9
3.4
1132.43
311.43
mg/l
1.33
283
2954
27
237
1.14
0.22
1.0
1.1
0.09
0.73
u/ml
—
8
83
7
94
0.74
0.22
1.9
3.3
—
17.64
—
0
10
7
95
0.73
0.22
1.0
1.1
—
—
—
0
0
203
1945
1.04
0.22
1.6
2.0
—
—
—
0
0
10
124
0.80
0.22
1.1
1.1
—
12.24
—
0
25
5
41
1.22
0.22
1.0
1.4
1020003.90
917246.34
nmol/l
—
5
29
15
125
1.20
0.22
1.2
1.2
—
—
—
0
0
52
563
0.92
0.21
1.1
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
2489.80
—
0
10
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
1.32
—
0
6
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
52
562
0.92
0.21
1.1
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
10.17
—
0
6
0
13
0.00
0.21
0.0
1.0
—
8.00
—
0
6
833
8435
0.98
0.21
6.8
6.3
1.22
1.22
mmol/l
0.05
770
7834
460
4691
0.97
0.20
2.5
2.6
2584.98
3445.54
umol/l
0.31
426
4249
0
14
0.00
0.20
0.0
1.1
—
7.87
—
0
8
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
143
1363
1.05
0.20
1.8
2.6
—
—
—
0
0
193
1853
1.04
0.20
1.4
1.4
—
—
—
0
0
6
52
1.15
0.19
1.3
1.4
—
—
—
0
0
19
165
1.15
0.18
6.1
5.4
11.73
11.46
%
0.12
19
165
13
153
0.85
0.18
1.0
1.0
—
—
—
0
0
28
251
1.11
0.18
1.0
1.1
—
—
—
0
0
56
597
0.93
0.17
4.4
5.4
—
—
—
0
0
41
377
1.09
0.17
1.3
1.4
6.33
6.89
mmol/l
0.82
31
343
11
130
0.84
0.16
1.3
1.3
—
—
—
0
0
8
70
1.14
0.16
1.5
2.9
—
—
—
0
0
139
1334
1.04
0.16
5.8
4.8
70.99
73.82
ng/l
0.20
122
1224
32
348
0.92
0.15
2.9
3.2
45.08
30.13
mg/l
0.27
24
278
32
348
0.92
0.15
2.9
3.3
26.52
71.69
mg/l
1.33
24
278
8
73
1.09
0.15
4.1
1.5
—
—
—
0
0
8
73
1.09
0.15
1.6
3.0
29.61
20.48
mmol/l
—
8
65
249
2418
1.03
0.15
1.3
1.4
—
—
—
0
0
60
634
0.94
0.15
7.2
8.1
—
—
—
0
0
539
5288
1.02
0.15
4.1
3.7
7.40
7.40
ph
0.28
133
1021
160
1543
1.04
0.15
1.7
2.1
—
—
—
0
0
9
81
1.11
0.15
1.2
1.0
—
—
—
0
0
50
467
1.07
0.15
1.2
1.2
—
—
—
0
0
25
226
1.10
0.14
2.6
1.9
—
—
—
0
0
11
128
0.86
0.14
1.0
1.3
—
69.38
%
—
0
13
38
352
1.08
0.14
1.3
1.5
—
—
—
0
0
199
1930
1.03
0.14
1.6
2.0
—
—
—
0
0
21
232
0.90
0.14
1.0
1.1
—
—
—
0
0
8
97
0.82
0.13
1.1
1.1
—
—
—
0
0
8
97
0.82
0.13
1.0
1.2
—
—
—
0
0
8
98
0.81
0.13
6.0
4.4
—
—
—
0
0
8
98
0.81
0.13
1.0
1.0
—
—
—
0
0
745
7339
1.02
0.13
4.0
3.5
37.50
73.30
e6/l
1.91
525
4908
8
99
0.81
0.13
1.3
1.3
0.02
1.13
u/ml
—
8
99
662
6516
1.02
0.13
2.4
2.3
—
—
—
0
0
37
343
1.08
0.13
1.6
2.0
4.75
5.33
mmol/24h
0.61
32
310
34
314
1.08
0.13
2.3
1.6
—
—
—
0
0
158
1528
1.03
0.13
1.3
1.3
58.76
39.62
au/ml
—
10
77
39
416
0.93
0.13
2.5
2.2
—
—
—
0
0
441
4326
1.02
0.13
3.8
4.0
—
—
—
0
0
11
127
0.86
0.13
1.0
1.1
3.42
15.46
u/ml
1.28
11
91
45
477
0.94
0.13
1.2
1.3
—
—
—
0
0
55
520
1.06
0.12
1.5
1.4
21.92
21.67
u/l
0.02
41
443
10
85
1.17
0.12
1.3
1.3
—
—
—
0
0
51
536
0.95
0.11
2.1
1.8
—
—
—
0
0
23
210
1.09
0.11
1.7
1.6
—
—
—
0
0
83
860
0.96
0.11
2.1
2.1
—
—
—
0
0
196
1909
1.03
0.11
1.6
2.0
—
—
—
0
0
506
4980
1.02
0.11
3.2
3.1
—
—
—
0
0
52
494
1.05
0.10
1.9
1.6
—
—
—
0
0
19
207
0.91
0.10
1.0
1.0
295.16
292.19
mg/l
0.04
19
192
5
44
1.13
0.10
1.0
2.7
—
—
—
0
0
608
5999
1.01
0.10
3.7
3.1
25.56
66.61
e6/l
2.03
495
4523
35
370
0.94
0.09
1.9
2.5
145.61
122.53
ug/min
0.06
20
237
14
155
0.90
0.09
1.3
1.2
—
56.31
—
0
14
57
545
1.04
0.09
1.6
1.4
—
7.53
—
0
12
178
1739
1.02
0.08
1.5
1.6
—
—
—
0
0
17
185
0.92
0.08
1.1
1.1
—
—
—
0
0
14
126
1.11
0.08
1.7
2.8
38.93
35.94
mmol/l
0.17
14
121
5
63
0.79
0.08
1.2
1.5
—
—
—
0
0
12
107
1.12
0.08
1.4
3.0
2.28
2.64
mmol/l
0.31
12
101
171
1672
1.02
0.08
2.5
2.3
19.23
23.66
au/ml
0.31
14
152
850
8416
1.01
0.08
1.9
1.9
—
—
—
0
0
184
1801
1.02
0.08
1.6
2.0
—
—
—
0
0
10
112
0.89
0.07
1.0
1.4
—
—
—
0
0
14
153
0.91
0.07
3.1
4.7
10.14
8.57
mg/l
—
9
129
17
156
1.09
0.07
1.9
1.4
10254.91
77821.37
e6/l
0.86
11
108
32
303
1.05
0.07
1.0
1.1
1.44
1.46
g/l
0.19
32
276
15
137
1.09
0.07
1.5
1.7
—
—
—
0
0
56
578
0.97
0.07
3.3
3.0
—
—
—
0
0
83
850
0.97
0.07
1.1
1.1
6.14
7.68
u/ml
0.31
45
503
254
2499
1.01
0.07
1.3
1.2
—
—
—
0
0
45
432
1.04
0.06
1.1
1.1
—
—
—
0
0
16
172
0.93
0.06
3.0
2.9
39406.25
40366.05
ug/l
0.15
16
172
41
424
0.96
0.05
1.2
1.3
4.54
4.23
u/ml
0.07
13
185
99
968
1.02
0.05
3.8
3.2
20.80
21.34
s
0.93
83
845
173
1702
1.01
0.05
6.2
9.0
13.10
13.39
kpa
0.30
160
1636
173
1702
1.01
0.05
6.2
9.0
5.02
5.11
kpa
0.83
160
1633
11
100
1.10
0.05
1.1
1.2
—
—
—
0
0
172
1694
1.01
0.04
6.1
9.1
1.32
0.94
mmol/l
0.72
126
1350
17
160
1.06
0.03
1.2
1.3
1.56
1.58
g/l
0.09
17
160
17
179
0.95
0.03
1.1
1.0
—
—
—
0
0
39
400
0.97
0.03
1.9
1.7
5749.88
11226.96
e6/l
1.38
32
294
14
131
1.07
0.03
6.3
6.8
—
—
—
0
0
14
131
1.07
0.03
1.6
3.0
997.14
944.47
u/ml
0.04
14
131
90
884
1.02
0.03
1.9
2.6
—
—
—
0
0
19
181
1.05
0.02
1.2
1.2
—
—
—
0
0
16
152
1.05
0.02
1.1
1.2
—
7.00
—
0
13
47
460
1.02
0.02
1.1
1.1
8.77
1078.24
iu/ml
0.60
11
134
76
766
0.99
0.01
2.0
1.4
204.26
228.12
u/ml
0.30
43
431
44
446
0.98
0.01
1.1
1.1
—
—
—
0
0
10
106
0.94
0.01
1.0
1.4
138.44
160.17
mmol/24h
—
10
106
298
2980
1.00
0.01
6.2
4.6
0.83
0.82
mmol/l
0.94
283
2838
58
572
1.01
0.00
1.2
1.1
8.66
14.93
au/ml
—
5
37
12
114
1.05
0.00
1.5
1.4
142.92
134.25
nmol/l
0.18
12
114
10
103
0.97
0.00
1.4
1.2
—
—
—
0
0
16
160
1.00
0.00
1.0
1.2
2.18
10.80
u/ml
—
9
104
266
2656
1.00
0.00
1.8
1.9
—
—
—
0
0
292
2912
1.00
0.00
2.2
2.6
2.42
2.42
mmol/l
0.06
261
2552
113
1125
1.00
0.00
3.8
2.5
67.44
67.25
g/l
0.10
107
1060
11
115
0.95
0.00
1.1
1.1
—
—
—
0
0
11
112
0.98
0.00
1.8
3.3
—
—
—
0
0
25
250
1.00
0.00
1.1
1.3
—
—
nmol/l
—
0
0
10
104
0.96
0.00
1.6
2.4
2136.50
2041.21
ml
—
10
96
24
241
0.99
0.00
1.4
1.2
—
—
—
0
0
18
183
0.98
0.00
1.4
1.2
—
—
—
0
0
26
262
0.99
0.00
1.8
2.2
66.10
71.14
mmol/l
0.24
21
228
53
528
1.00
0.00
3.2
3.5
940.56
2487.16
u/ml
0.34
45
445
24
237
1.01
0.00
1.6
1.8
—
—
—
0
0
17
170
1.00
0.00
2.6
2.6
5.23
1.64
g/24h
—
8
100
21
214
0.98
0.00
3.2
2.7
596.57
683.22
e6/l
0.47
21
209
27
271
0.99
0.00
3.2
3.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
58.22
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
9
99
0.91
-0.00
1.2
1.4
72.78
81.73
nmol/24h
—
9
99
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
58
0.86
-0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.6
—
—
—
0
0
5
58
0.86
-0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
4.62
—
0
7
5
58
0.86
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
7.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_MN_RETRGN and mortality.

Females

Parameter HR [95% CI] p-value
K11_MN_RETRGN 0.672 [0.55, 0.82] < 0.001
Birth year 0.993 [0.98, 1.0] 0.098

During the follow-up period (1.1.1998 — 31.12.2019), 137 out of 24333 females with K11_MN_RETRGN died.

Males

Parameter HR [95% CI] p-value
K11_MN_RETRGN 0.617 [0.5, 0.76] < 0.001
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 140 out of 22122 males with K11_MN_RETRGN died.

Mortality risk

Mortality risk for people of age

years, who have K11_MN_RETRGN.

N-year risk Females Males
1 0.071% 0.101%
5 0.414% 0.666%
10 0.931% 1.732%
15 1.766% 3.259%
20 3.271% 5.687%

Relationships between endpoints

Index endpoint: K11_MN_RETRGN – Mandibular retrognathia

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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