Astigmatism

H7_ASTIGMATISM

obsolete_astigmatism: ['Unequal curvature of the refractive surfaces of the eye. Thus a point source of light cannot be brought to a point focus on the retina but is spread over a more or less diffuse area. This results from the radius of curvature in one plane being longer or shorter than the radius at right angles to it. (Dorland, 27th ed).']

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H52.2
  • Hospital discharge: ICD-9 3672
  • Hospital discharge: ICD-8 37000
  • Cause of death: ICD-10 H52.2
  • Cause of death: ICD-9 3672
  • Cause of death: ICD-8 37000

2 out of 7 registries used, show all original rules.

2444

4. Check minimum number of events

None

2444

5. Include endpoints

None

2444

6. Filter based on genotype QC (FinnGen only)

2444

Control definitions (FinnGen only)

Control exclude
H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H52
Name in latin
Astigmatismus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 32598 16827 15677
Only index persons 24791 12908 11883
Unadjusted period prevalence (%)
Whole population 0.46 0.48 0.44
Only index persons 0.46 0.47 0.45
Median age at first event (years)
Whole population 8.05 8.10 7.83
Only index persons 12.81 12.99 12.61

-FinnGen-

Key figures

All Female Male
Number of individuals 2444 1422 1022
Unadjusted period prevalence (%) 0.47 0.48 0.45
Median age at first event (years) 43.77 38.93 50.51

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2154
Matched controls
21505
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H52.1
ICD-10 Finland
Myopia
59.1
323.0
451
96
H52.2
ICD-10 Finland
Astigmatism
9970.9
323.0
2058
23
H52.0
ICD-10 Finland
Hypermetropia
101.4
293.8
320
37
XCW99
NOMESCO Finland
Other investigative procedure of eye
5.7
133.4
429
904
H53.0
ICD-10 Finland
Amblyopia ex anopsia
37.7
99.8
128
36
H52.4
ICD-10 Finland
Presbyopia
22.4
99.7
147
70
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
87.3
89.8
100
12
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.3
88.1
518
1861
37000
ICD-8 Finland
Refractive errors, Astigmatismus
+∞
78.6
75
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.5
78.3
836
4324
H18.6
ICD-10 Finland
Keratoconus
41.8
76.7
96
24
CG2T4
NOMESCO Finland
Topography assessment of cornea
22.9
69.3
101
46
Z96.1
ICD-10 Finland
Presence of intraocular lens
3.9
65.3
298
855
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.0
62.2
273
755
H50.31
ICD-10 Finland
Intermittent exotropia
315.9
60.6
61
*
H50.52
ICD-10 Finland
Exophoria
74.1
57.3
65
9
H50.0
ICD-10 Finland
Convergent concomitant strabismus
540.2
53.7
53
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.5
51.7
506
2394
Z94.7
ICD-10 Finland
Corneal transplant status
52.2
51.0
61
12
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
24.8
49.5
70
29
ZXA10
NOMESCO Finland
Bilateral
2.5
47.8
453
2100
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.5
46.6
234
718
CGD20
NOMESCO Finland
Laser-assisted in situ keratomileusis
+∞
44.9
43
*
H53.2
ICD-10 Finland
Diplopia
7.6
43.9
106
146
H50.30
ICD-10 Finland
Intermittent esotropy
+∞
43.9
42
*
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
152.8
42.9
45
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.9
42.5
290
1105
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.1
42.1
621
3508
H53.1
ICD-10 Finland
Subjective visual disturbances
3.9
41.9
185
509
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
41.8
40
*
H50.1
ICD-10 Finland
Divergent concomitant strabismus
213.7
41.0
42
*
H04.10
ICD-10 Finland
Dry eye syndrome
3.1
40.7
246
863
CGD99
NOMESCO Finland
Other operation for error of refraction
+∞
39.7
38
*
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
9.4
39.5
83
91
H40.0
ICD-10 Finland
Glaucoma suspect
3.7
37.6
175
503
XA800
NOMESCO Finland
Neuropsychological investigation
3.7
34.3
158
450
H25.1
ICD-10 Finland
Senile nuclear cataract
2.2
32.9
389
1970
XCK10
NOMESCO Finland
Photography of fundus of eye
2.8
32.8
227
864
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.6
32.8
155
451
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
32.4
607
3690
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
32.0
810
5445
XCK00
NOMESCO Finland
Perimetry
3.6
32.0
154
455
CGD10
NOMESCO Finland
Laser keratoplasty for error of refraction
73.2
31.9
36
5
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.7
27.7
208
830
TCG10
NOMESCO Finland
Removal of sutures from cornea
17.1
26.6
42
25
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.7
26.4
190
740
R51.80
ICD-10 Finland
Headache
2.0
25.4
352
1888
R4110
NOMESCO Finland
Physiotherapy
1.8
24.2
528
3323
H50.2
ICD-10 Finland
Vertical strabismus
87.6
23.7
26
*
ZXA00
NOMESCO Finland
Right side
1.8
23.6
489
3023
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
12.6
23.6
42
34
R42
ICD-10 Finland
Dizziness and giddiness
1.9
23.1
373
2117
H26.4
ICD-10 Finland
After-cataract
2.8
22.7
153
572
AA1AD
NOMESCO Finland
CT of head and brain
1.9
22.4
403
2372
H25.0
ICD-10 Finland
Senile incipient cataract
3.4
22.4
112
342
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
10.9
22.1
42
39
3672A
ICD-9 Finland
Disorders of refraction and accommodation, Astigmatism
+∞
21.9
21
*
WX110
NOMESCO Finland
Local anesthesy
1.6
21.8
1462
12279
R5140
NOMESCO Finland
Monitoring the use of the aid
2.4
21.4
197
877
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
21.1
421
2562
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.4
21.1
194
863
ZXA05
NOMESCO Finland
Left side
1.8
20.9
449
2793
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
20.8
20
*
H26.02
ICD-10 Finland
Presenil cataract
4.8
20.7
70
150
WX002
NOMESCO Finland
Sedation and analgesia
1.8
20.5
366
2143
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
19.9
432
2693
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
19.8
19
*
N05BA04
ATC
oxazepam; oral
1.7
19.6
433
2715
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
19.1
391
2390
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
19.1
309
1747
WX140
NOMESCO Finland
Parabulbar anesthesy
3.5
18.9
90
265
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
+∞
18.8
18
*
114
Kela drug reimbursment
Glaucoma
2.6
18.3
138
550
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
18.2
314
1809
N02AX02
ATC
tramadol; systemic, rectal
1.6
18.0
690
5000
3716A
ICD-9 Finland
Corneal opacity and other disorders of cornea, Keratoconus
181.1
17.5
18
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.2
17.4
176
820
N03AX09
ATC
lamotrigine; oral
2.7
17.2
122
472
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
17.1
327
1950
TAB00
NOMESCO Finland
Lumbar puncture
2.8
17.1
110
402
N05BA01
ATC
diazepam; systemic, rectal
2.0
16.9
242
1303
P85
ICPC
Mental retardation
11.2
16.7
31
28
SPAT1263
SPAT
Sampling
1.5
16.5
853
6571
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.5
16.3
127
518
A02BC02
ATC
pantoprazole; systemic
1.5
16.2
1078
8742
R03AC02
ATC
salbutamol; inhalant
1.5
16.1
1022
8208
M79.6
ICD-10 Finland
Pain in limb
1.5
16.0
619
4469
H54.7
ICD-10 Finland
Unspecified visual loss
10.1
15.9
31
31
S01EE01
ATC
latanoprost; ophthalmic
2.9
15.6
97
347
CHW99
NOMESCO Finland
Other operation on anterior chamber, anterior chamber angle, iris or ciliary body
85.6
15.6
17
*
H50.51
ICD-10 Finland
Esophoria
85.6
15.6
17
*
G47.3
ICD-10 Finland
Sleep apnoea
1.7
15.4
339
2108
N06AX11
ATC
mirtazapine; oral
1.6
15.4
537
3777
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
15.3
850
6616
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
8.3
15.2
33
40
F83
ICD-10 Finland
Mixed specific developmental disorders
4.2
15.1
57
138
H53.4
ICD-10 Finland
Visual field defects
4.5
15.1
53
120
N03AG01
ATC
valproic acid; systemic, rectal
2.4
15.0
133
580
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.5
14.7
69
202
N03AX14
ATC
levetiracetam; systemic
3.3
14.7
73
224
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
14.5
463
3176
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
14.2
14.5
24
17
R53
ICD-10 Finland
Malaise and fatigue
1.7
14.5
370
2399
3604
FHL
Penetration of the cornea
150.7
14.5
15
*
N03AX16
ATC
pregabalin; oral
1.6
14.3
370
2403
R06.0
ICD-10 Finland
Dyspnoea
1.6
14.3
399
2645
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.8
14.2
280
1679
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.0
14.2
81
273
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
14.1
245
1409
H25.8
ICD-10 Finland
Other senile cataract
2.2
14.0
145
682
N06AX16
ATC
venlafaxine; oral
1.8
14.0
257
1508
R02
ICPC
Shortness of breath/dyspnoea
1.9
14.0
221
1230
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.1
13.8
164
821
N03AX12
ATC
gabapentin; oral
1.8
13.7
247
1438
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
13.6
420
2858
N05BA09
ATC
clobazam; oral
5.6
13.6
39
71
N06AB04
ATC
citalopram; systemic
1.7
13.6
343
2213
H17.8
ICD-10 Finland
Other corneal scars and opacities
14.8
13.6
22
15
CEC00
NOMESCO Finland
Recession of extraocular muscle
+∞
13.5
13
*
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
13.4
867
6902
UDC00
NOMESCO Finland
Ear microscopy
2.1
13.4
161
809
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
12.9
13.4
23
18
CG2Z4
NOMESCO Finland
Specialised imaging of cornea
25.9
13.4
18
7
N05AH04
ATC
quetiapine; oral
1.7
13.2
320
2038
A11
ICPC
Chest pain NOS
2.2
13.2
135
634
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
13.1
378
2521
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
3.1
13.1
71
233
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.2
13.1
129
596
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
13.0
261
1577
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
12.9
286
1774
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
19.1
12.9
19
10
TCG30
NOMESCO Finland
Imaging of anterior and posterior part of cornea
22.6
12.9
18
8
N02BE01
ATC
paracetamol; systemic, rectal
1.4
12.8
1567
13966
CG2S4
NOMESCO Finland
Photography of cornea
9.7
12.7
25
26
N06AX21
ATC
duloxetine; oral
2.0
12.7
176
935
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.1
12.6
146
722
H40.11
ICD-10 Finland
Low pressure glaucoma
4.7
12.6
42
91
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.3
12.6
120
545
N05CF01
ATC
zopiclone; oral
1.5
12.6
475
3378
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
3.3
12.5
62
191
S01EE05
ATC
tafluprost; ophthalmic
3.4
12.5
59
175
183
Kela drug reimbursment
Lamotrigin and topiramate
5.0
12.4
39
79
SPAT1301
SPAT
No procedures
1.5
12.4
606
4550
Z31.5
ICD-10 Finland
Genetic counselling
2.3
12.4
116
520
S18
ICPC
Laceration/cut
1.4
12.4
719
5585
R06.5
ICD-10 Finland
Mouth breathing
2.0
12.3
168
889
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
12.3
1437
12636
M54.5
ICD-10 Finland
Low back pain
1.5
12.3
565
4190
-50
ICPC
Medication/prescr/renewal
2.7
12.1
84
322
F29
ICPC
Eye symptom/complaint other
1.9
12.1
174
938
R62.0
ICD-10 Finland
Delayed milestone
3.6
12.0
54
154
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
3.7
12.0
51
139
F82
ICD-10 Finland
Specific developmental disorder of motor function
4.2
12.0
44
105
H26.2
ICD-10 Finland
Complicated cataract
5.5
11.9
34
62
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
11.8
414
2890
S01ED51
ATC
timolol, combinations; ophthalmic
2.3
11.8
107
475
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
11.7
452
3228
N06AB10
ATC
escitalopram; oral
1.6
11.7
377
2581
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
11.7
678
5255
C07AA05
ATC
propranolol; systemic
1.6
11.5
330
2194
FEMTO
NOMESCO Finland
NA
+∞
11.5
11
*
3619
FHL
Other operations in this group, such as corneal refractive surgery
120.4
11.4
12
*
H02AB06
ATC
prednisolone; systemic
1.4
11.4
774
6161
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.9
11.3
171
938
J01DB01
ATC
cefalexin; oral
1.4
11.3
1589
14313
CHD00
NOMESCO Finland
Laser trabeculoplasty
5.3
11.2
33
63
N06AX12
ATC
bupropion; oral
2.1
11.2
123
598
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.7
11.1
253
1580
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.9
11.1
173
960
-1
NOMESCO Finland
NA
1.4
11.1
751
5974
H57.1
ICD-10 Finland
Ocular pain
2.9
11.0
65
228
H02.4
ICD-10 Finland
Ptosis of eyelid
3.3
10.9
54
167
H52.5
ICD-10 Finland
Disorders of accommodation
43.5
10.9
13
*
L03
ICPC
Low back symptom/complaint
1.5
10.9
429
3068
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.1
10.8
129
646
H03AA01
ATC
levothyroxine sodium; systemic
1.5
10.8
358
2464
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
15.5
10.8
17
11
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
10.8
440
3171
G44.2
ICD-10 Finland
Tension-type headache
1.7
10.8
228
1396
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.8
10.8
178
1010
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.1
10.7
119
578
XKC03
NOMESCO Finland
Water cystometry
3.0
10.5
61
210
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
5.1
10.4
32
64
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
10.4
1033
8716
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
110.3
10.4
11
*
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.7
10.4
69
258
L28
ICPC
Limited function/disability (L)
1.7
10.4
224
1379
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
3.8
10.4
42
111
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
6.4
10.3
26
41
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
10.3
414
2973
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
10.2
1012
8527
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.2
10.2
107
509
N01
ICPC
Headache
1.6
10.2
301
2012
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
10.2
467
3443
R11
ICD-10 Finland
Nausea and vomiting
1.8
10.1
165
929
L04AD01
ATC
ciclosporin; systemic
3.3
10.1
50
156
N05AH03
ATC
olanzapine; systemic
2.1
10.0
117
583
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
3.5
10.0
45
130
N03AF02
ATC
oxcarbazepine; oral
2.5
10.0
74
296
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.8
10.0
171
981
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
9.9
208
1270
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.1
9.9
109
531
K59.0
ICD-10 Finland
Constipation
2.2
9.8
99
465
R4120
NOMESCO Finland
Occupational therapy
2.0
9.8
123
630
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
9.7
115
577
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
9.7
300
2029
KMAK
NOMESCO Finland
NA
1.3
9.7
916
7642
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.8
9.6
58
207
F05
ICPC
Visual disturbance other
2.8
9.6
61
224
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
9.6
345
2416
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
9.6
264
1737
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
9.6
338
2355
N06AB06
ATC
sertraline; oral
1.7
9.5
198
1205
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.0
9.5
52
174
R05
ICPC
Cough
1.5
9.5
429
3147
H18.4
ICD-10 Finland
Corneal degeneration
9.1
9.5
19
21
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
10.1
9.5
18
18
M41.4
ICD-10 Finland
Neuromuscular scoliosis
15.1
9.5
15
10
H27.8
ICD-10 Finland
Other specified disorders of lens
15.1
9.5
15
10
N03AG04
ATC
vigabatrin; oral
15.1
9.5
15
10
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
9.5
172
1003
R20.2
ICD-10 Finland
Paraesthesia of skin
2.0
9.5
119
611
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
9.4
397
2872
SPAT1097
SPAT
Recording of ECG
1.7
9.4
213
1326
37103
ICD-8 Finland
Corneal opacity, Keratoconus
100.3
9.4
10
*
S01GX01
ATC
cromoglicic acid; ophthalmic
1.5
9.4
367
2615
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
+∞
9.4
9
*
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
9.4
9
*
UKC02
NOMESCO Finland
Cystoscopy
1.6
9.3
222
1405
S01ED01
ATC
timolol; ophthalmic
2.9
9.2
55
195
C07AB07
ATC
bisoprolol; oral
1.4
9.2
646
5126
N05CF02
ATC
zolpidem; oral
1.6
9.2
266
1770
R51
ICD-10 Finland
Headache
2.0
9.2
110
553
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
9.2
297
2027
R5599
NOMESCO Finland
Other rehabilitation service
2.7
9.2
62
236
181
Kela drug reimbursment
Retigabine and vigabatrin
13.7
9.2
15
11
A98
ICPC
Health maint/preventive medicine
1.8
9.1
2058
19793
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.4
9.1
75
319
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
9.1
479
3616
RL140
NOMESCO Finland
NA
5.9
9.0
24
41
L17
ICPC
Foot/toe symptom/complaint
1.4
9.0
451
3373
H01
ICPC
Ear pain/earache
1.6
9.0
262
1744
L01
ICPC
Neck symptom/complaint
1.6
9.0
244
1598
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
9.0
694
5596
N05BA12
ATC
alprazolam; oral
1.8
8.9
150
857
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
8.9
314
2187
D11
ICPC
Diarrhoea
1.6
8.9
227
1464
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.0
8.8
114
591
A28
ICPC
Limited function/disability NOS
1.7
8.8
198
1234
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
8.8
1370
12228
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.0
8.7
109
558
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
5.4
8.7
25
47
H54.3
ICD-10 Finland
Mild or no visual impairment, binocular
14.1
8.7
14
10
Q90.0
ICD-10 Finland
Trisomy 21, meiotic nondisjunction
50.1
8.7
10
*
H18.7
ICD-10 Finland
Other corneal deformities
50.1
8.7
10
*
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
3.5
8.7
39
114
R1250
NOMESCO Finland
Evaluation of functional capability
3.2
8.6
44
141
K59.09
ICD-10 Finland
Constipation, unspecified
2.0
8.6
110
567
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.2
8.6
86
403
UJF30
NOMESCO Finland
Ileoscopy through colon
1.8
8.6
152
881
N03AE01
ATC
clonazepam; systemic
2.2
8.6
88
416
N05AA02
ATC
levomepromazine; systemic
2.4
8.6
67
279
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.7
8.6
174
1052
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
8.6
615
4891
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.6
8.5
60
236
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.8
8.5
52
188
Z71.8
ICD-10 Finland
Other specified counselling
1.4
8.5
458
3468
Z94.0
ICD-10 Finland
Kidney transplant status
3.9
8.5
33
85
L05
ICPC
Flank/axilla symptom/complaint
2.1
8.5
97
482
N06AX26
ATC
vortioxetine; oral
2.0
8.5
105
537
H17.1
ICD-10 Finland
Other central corneal opacity
20.1
8.5
12
6
A02BC05
ATC
esomeprazole; systemic
1.4
8.4
619
4937
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
3.1
8.4
44
144
G35
ICD-10 Finland
Multiple sclerosis
3.7
8.4
35
96
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
8.4
140
798
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
8.4
1063
9187
CJF50
NOMESCO Finland
Removal and implantation of artificial lens in posterior chamber
90.2
8.4
9
*
R74
ICPC
Upper respiratory infection acute
1.4
8.4
625
4995
H16.8
ICD-10 Finland
Other keratitis
12.8
8.4
14
11
A02BC01
ATC
omeprazole; systemic
1.4
8.4
414
3086
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.5
8.3
311
2189
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
8.3
153
896
127
Kela drug reimbursment
Transplant complication
3.3
8.3
40
123
3671A
ICD-9 Finland
Disorders of refraction and accommodation, Myopia
+∞
8.3
8
*
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
3.6
8.3
36
102
S01EC01
ATC
acetazolamide; systemic
3.3
8.3
39
118
WX402
NOMESCO Finland
General anaesthesia
1.5
8.3
312
2203
SPAT1260
SPAT
Consultation of another employee
1.5
8.3
309
2178
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
8.3
142
816
WX320
NOMESCO Finland
Spinalanesthesy
1.5
8.3
325
2315
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
8.3
525
4089
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
4.8
8.2
26
55
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
8.2
1045
9024
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.8
8.2
129
722
P06
ICPC
Sleep disturbance
1.7
8.2
177
1090
XF602
NOMESCO Finland
Bloodpressure monitoring
4.2
8.2
29
69
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
3.0
8.2
45
153
N03AX11
ATC
topiramate; oral
2.7
8.1
54
206
CKD60
NOMESCO Finland
Anterior vitrectomy
7.5
8.1
18
24
SPAT1153
SPAT
Removal of sutures
1.4
8.1
488
3763
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.1
8.1
92
456
R01AD09
ATC
mometasone; nasal
1.3
8.1
786
6531
XKD00
NOMESCO Finland
Uroflowmetry
1.6
8.1
217
1418
CGF10
NOMESCO Finland
Suture of laceration of cornea
33.4
8.1
10
*
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
11.7
8.1
14
12
A02BA02
ATC
ranitidine; systemic
1.5
8.0
266
1827
H66.9
ICD-10 Finland
Otitis media, unspecified
1.6
8.0
196
1249
XF600
NOMESCO Finland
Bloodpressure measurement
1.8
8.0
136
778
N06AB03
ATC
fluoxetine; oral
1.6
8.0
208
1347
S01EA03
ATC
apraclonidine; ophthalmic
5.3
8.0
23
44
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.2
7.9
40
128
M25.5
ICD-10 Finland
Pain in joint
1.4
7.9
473
3640
H01AC01
ATC
somatropin; parenteral
3.9
7.9
31
81
H02AB09
ATC
hydrocortisone; systemic
2.5
7.9
61
250
M79.1
ICD-10 Finland
Myalgia
1.6
7.9
207
1343
WX780
NOMESCO Finland
Remote monitoring CPAP
2.3
7.9
67
290
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
13.0
7.9
13
10
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
13.0
7.9
13
10
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
3.7
7.8
32
87
S01AX11
ATC
[U] ofloxacin; ophthalmic
2.5
7.8
57
228
SDA02
NOMESCO Finland
Parodonthologic therapy
1.3
7.8
590
4718
A01
ICPC
Pain general/multiple sites
1.8
7.8
127
721
J01MA02
ATC
ciprofloxacin; systemic
1.3
7.7
565
4492
H02AB04
ATC
methylprednisolone; systemic
1.6
7.7
216
1423
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.8
7.7
139
809
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.5
7.7
316
2267
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
7.7
712
5863
N06AG02
ATC
moclobemide; oral
2.3
7.7
69
307
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.0
7.7
97
499
H81
ICPC
Excessive ear wax
1.6
7.7
226
1508
WX400
NOMESCO Finland
Inhalation anesthesy
1.9
7.7
103
543
RS311
NOMESCO Finland
NA
7.4
7.7
17
23
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.5
7.6
228
1529
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.1
7.6
79
378
G04BD12
ATC
mirabegron; oral
1.8
7.6
133
772
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
18.4
7.6
11
6
CGG11
NOMESCO Finland
Corneal cross-linking
18.4
7.6
11
6
D06
ICPC
Abdominal pain localized other
1.7
7.6
158
966
R01AD12
ATC
fluticasone furoate; nasal
1.3
7.6
536
4242
RK110
NOMESCO Finland
NA
4.5
7.5
25
56
CHC05
NOMESCO Finland
Iridotomy
3.7
7.5
31
85
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
7.5
891
7590
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.5
7.5
241
1640
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
7.5
154
936
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
2.7
7.5
48
179
G43.3
ICD-10 Finland
Complicated migraine
3.2
7.5
36
112
3718X
ICD-9 Finland
Corneal opacity and other disorders of cornea, Other corneal disorders
80.2
7.4
8
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
1.9
7.4
109
598
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
13.4
7.4
12
9
H18.8
ICD-10 Finland
Other specified disorders of cornea
7.7
7.4
16
21
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.0
7.4
86
432
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.9
7.3
108
589
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
8.4
7.3
15
18
WX892
NOMESCO Finland
Monitored bed care
1.7
7.3
132
774
CJA00
NOMESCO Finland
Implantation of phakic lens in anterior chamber
+∞
7.3
7
*
37002
ICD-8 Finland
Refractive errors, Myopia
+∞
7.3
7
*
J01FF01
ATC
clindamycin; systemic
1.4
7.3
419
3202
RT150
NOMESCO Finland
NA
4.5
7.2
24
54
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
7.2
359
2672
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
7.2
633
5166
H13
ICPC
Plugged feeling ear
1.5
7.2
260
1818
J01DA01
ATC
[U] cefalexin; systemic
1.3
7.2
1060
9274
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
4.6
7.2
23
50
RS220
NOMESCO Finland
NA
2.9
7.2
41
141
L02
ICPC
Back symptom/complaint
1.6
7.2
164
1029
WX720
NOMESCO Finland
Own respiration
2.3
7.2
63
280
-31
ICPC
Medical examin/health eval partial
1.7
7.1
133
789
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.7
7.0
143
866
S01EC04
ATC
brinzolamide; ophthalmic
2.4
7.0
54
225
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
7.0
143
868
K59.1
ICD-10 Finland
Functional diarrhoea
2.0
7.0
83
417
M03BX02
ATC
tizanidine; oral
1.3
7.0
980
8505
J01AA02
ATC
doxycycline; systemic
1.3
7.0
1263
11316
R01AD08
ATC
fluticasone; nasal
1.4
7.0
459
3583
RD210
NOMESCO Finland
NA
2.3
7.0
59
258
602
Kela drug reimbursment
Children's severe malnutrition
3.3
6.9
32
97
TJD20
NOMESCO Finland
Change of gastrostomy tube
5.2
6.9
20
39
E0000UV
ATC
NA
1.3
6.9
731
6112
C08CA01
ATC
amlodipine; oral
1.4
6.9
437
3387
H02AB07
ATC
prednisone; oral
1.5
6.9
202
1348
Z01.9
ICD-10 Finland
Special examination, unspecified
1.9
6.9
89
467
SGA03
NOMESCO Finland
Demanding opening and dilatation of root canal of tooth
1.7
6.9
151
935
R52.2
ICD-10 Finland
Other chronic pain
2.4
6.9
53
222
SPAT1009
SPAT
Measurement of intraocular pressure
3.8
6.8
27
72
C09CA06
ATC
candesartan; oral
1.4
6.8
291
2101
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.5
6.8
246
1721
R35
ICD-10 Finland
Polyuria
1.9
6.8
94
501
J02AC01
ATC
fluconazole; systemic
1.3
6.8
609
4977
K04.0
ICD-10 Finland
Pulpitis
1.6
6.8
173
1117
J01CA04
ATC
amoxicillin; systemic
1.3
6.8
1685
15713
J01FA10
ATC
azithromycin; systemic
1.3
6.8
1153
10234
ZX198
NOMESCO Finland
Other local administration
4.0
6.8
25
63
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
6.8
231
1596
R06.4
ICD-10 Finland
Hyperventilation
2.9
6.8
37
127
BE00A
NOMESCO Finland
NA
16.7
6.7
10
6
R05
ICD-10 Finland
Cough
1.4
6.7
334
2487
N17
ICPC
Vertigo/dizziness
1.6
6.7
172
1113
F90.0
ICD-10 Finland
Disturbance of activity and attention
2.0
6.7
87
454
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.9
6.7
97
528
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
2.8
6.7
40
145
D02
ICPC
Abdominal pain epigastric
1.8
6.7
101
560
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
6.7
939
8139
CGD40
NOMESCO Finland
Implantation of intracorneal ring segments
22.5
6.7
9
*
WX199
NOMESCO Finland
Other local analgesia
2.6
6.7
44
169
N99
ICPC
Neurological disease other
4.9
6.6
20
41
K03.00
ICD-10 Finland
Approximal wear
1.9
6.6
87
458
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.6
1114
9864
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.2
6.6
64
296
M03BX01
ATC
baclofen; systemic
3.4
6.6
30
90
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
4.2
6.6
23
55
SPAT1310
SPAT
Counselling related to known health issue
1.3
6.6
597
4886
N06AX03
ATC
mianserin; oral
2.1
6.6
69
333
R03BA05
ATC
fluticasone; inhalant
1.4
6.5
329
2451
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.5
6.5
198
1332
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
6.8
6.5
15
22
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.3
6.5
602
4937
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.6
6.5
152
961
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.0
6.5
77
391
XX4AW
NOMESCO Finland
NA
3.7
6.5
26
71
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
6.4
312
2309
R50.9
ICD-10 Finland
Fever, unspecified
1.4
6.4
259
1853
H26.00
ICD-10 Finland
Infantile, juvenile and presenile cataract
69.9
6.4
7
*
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.4
6.4
260
1860
N05AX12
ATC
aripiprazole; systemic
2.0
6.4
81
421
XKD06
NOMESCO Finland
Physiologic investigation of micturition
2.6
6.4
45
177
WX723
NOMESCO Finland
CPAP therapy
2.3
6.4
57
255
J31.0
ICD-10 Finland
Chronic rhinitis
1.7
6.4
130
792
L04AX01
ATC
azathioprine; systemic
2.0
6.3
78
399
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
6.3
542
4395
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
3.2
6.3
31
99
JDB00
NOMESCO Finland
Gastrostomy
8.2
6.3
13
16
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.6
6.3
43
169
C01DA14
ATC
isosorbide mononitrate; oral
1.6
6.3
163
1058
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
3.5
6.3
27
78
R96
ICPC
Asthma
1.7
6.3
134
827
S05.6
ICD-10 Finland
Penetrating wound of eyeball without foreign body
18.0
6.3
9
5
3780B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALTERNANS]
+∞
6.2
6
*
H51.1
ICD-10 Finland
Convergence insufficiency and excess
+∞
6.2
6
*
CGD00
NOMESCO Finland
Keratotomy for error of refraction
+∞
6.2
6
*
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
+∞
6.2
6
*
RS222
NOMESCO Finland
NA
2.9
6.2
34
117
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
6.2
233
1640
3046
Kela drug reimbursment
NA
26.7
6.2
8
*
CJF15
NOMESCO Finland
Secondary implantation of skleral fixed artificial lens in posterior chamber
26.7
6.2
8
*
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
4.8
6.2
19
40
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
2.2
6.2
59
273
CS494
NOMESCO Finland
Other visual field testing
3.0
6.2
33
112
H16.9
ICD-10 Finland
Keratitis, unspecified
2.9
6.2
34
118
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
3.2
6.2
29
90
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
3.9
6.2
23
59
D01
ICPC
Abdominal pain/cramps general
1.5
6.2
228
1601
A01AB09
ATC
miconazole; local oral
1.6
6.1
136
845
P05.1
ICD-10 Finland
Small for gestational age
6.3
6.1
15
24
WX725
NOMESCO Finland
Noninvasive ventilation
2.0
6.1
73
372
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
6.1
291
2146
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
6.1
131
807
31
HP
Congenital heart failure surgery
7.7
6.1
13
17
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
7.7
6.1
13
17
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
6.1
134
832
N05AX08
ATC
risperidone; systemic
1.7
6.1
119
716
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.4
6.1
307
2288
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.7
6.1
117
699
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.0
6.1
74
380
T08
ICPC
Weight loss
2.7
6.0
37
137
N06AA12
ATC
doxepin; systemic
2.1
6.0
67
330
A02BC03
ATC
lansoprazole; oral
1.3
6.0
393
3057

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1060
7425
1.75
38.56
6.0
5.2
36.3
36.2
g/l
0.22
969
6937
1001
6917
1.75
38.06
7.4
6.7
—
—
—
0
0
1206
8870
1.71
35.92
10.0
7.2
1.2
1.2
mmol/l
0.39
1025
7596
936
6585
1.68
31.73
10.4
8.2
1.2
1.2
inr
0.13
323
1988
1695
13905
1.71
31.50
8.1
7.0
82.3
81.8
u/l
0.12
1611
13102
1105
8126
1.65
31.47
9.7
6.7
1.2
1.2
mmol/l
0.56
1012
7422
1065
7766
1.66
31.31
3.1
2.4
74.4
74.1
nmol/l
0.16
979
7088
744
4963
1.72
30.51
4.7
3.8
7.4
7.4
ph
0.01
149
938
1220
9303
1.62
29.28
8.3
6.7
0.7
0.7
%
0.22
1152
8745
1250
9597
1.62
29.11
8.3
6.6
2.8
2.9
%
0.60
1176
8999
1256
9666
1.61
28.87
8.6
6.8
8.5
8.4
%
0.76
1188
9106
1374
10902
1.59
27.02
6.9
4.9
6.4
6.5
mmol/l
1.18
1269
10103
1286
10050
1.59
26.97
8.3
6.6
29.5
29.8
%
0.35
1213
9440
1296
10157
1.58
26.76
8.3
6.5
0.0
0.0
e9/l
0.05
1148
8755
1267
9887
1.58
26.58
8.1
6.4
56.0
55.5
%
0.83
1196
9328
1291
10122
1.58
26.51
8.3
6.5
0.6
0.6
e9/l
0.19
1146
8719
1329
10491
1.58
26.49
8.7
6.9
0.2
0.2
e9/l
0.31
1186
9188
341
1894
1.93
25.21
2.4
2.2
351.3
369.2
nmol/l
0.94
317
1752
1321
10490
1.56
25.06
8.3
6.5
2.0
2.0
e9/l
1.29
1180
9235
1430
11572
1.56
24.86
11.2
9.2
4.0
4.0
e9/l
0.14
1272
10066
930
6834
1.58
24.76
2.0
1.9
96.1
95.4
pmol/l
0.17
515
3657
1170
9116
1.54
23.65
6.3
6.2
11.5
11.7
umol/l
0.25
1104
8581
1786
15316
1.61
23.30
4.7
3.8
14.6
14.6
pmol/l
0.12
1632
14004
1591
13362
1.54
22.00
5.4
4.0
—
—
—
0
0
2154
19524
1.86
21.60
19.4
14.0
139.5
139.6
mmol/l
0.27
2122
18976
1523
12712
1.52
21.32
5.3
4.1
1918.8
2032.2
e6/l
0.02
16
155
2156
19566
1.85
21.28
19.5
14.1
3.9
3.9
mmol/l
0.08
2120
18973
697
4959
1.57
20.51
2.5
2.2
270.1
226.5
u/l
0.30
648
4694
2010
17962
1.66
19.97
5.6
4.5
2.6
1.9
mu/l
0.43
1877
16646
1638
14011
1.51
19.37
4.9
3.9
10.9
10.7
mm/h
0.26
1519
13015
102
385
2.72
19.01
5.8
3.9
—
—
—
0
0
408
2595
1.68
18.79
9.9
7.1
1.1
1.1
mmol/l
0.15
379
2420
438
2840
1.66
18.73
1.8
1.7
1063.6
1173.9
nmol/l
1.89
322
2167
1141
9146
1.46
18.32
12.7
9.5
0.0
0.0
e9/l
0.77
957
7387
769
5719
1.50
17.96
4.2
3.2
115.3
70.4
e6/l
0.21
601
4361
779
5829
1.49
17.58
3.3
3.2
2.4
2.4
mmol/l
0.08
675
5153
476
3207
1.60
17.31
3.9
3.6
330.8
510.3
ng/l
0.63
357
2256
429
2820
1.63
17.26
3.0
3.3
29.8
30.0
s
0.48
415
2747
222
1209
1.92
17.18
3.6
3.2
4.7
4.6
pmol/l
0.12
202
1082
2169
19973
1.75
16.95
16.8
12.5
21.6
23.1
mg/l
1.23
1734
15279
238
1335
1.86
16.81
5.3
4.7
74.4
77.2
ng/l
0.21
206
1194
712
5275
1.49
16.71
4.0
3.2
0.2
0.4
e6/l
2.98
547
3962
397
2580
1.64
16.67
3.0
2.5
2.4
2.4
g/l
0.05
365
2389
1836
16283
1.51
16.54
5.6
5.1
38.7
38.9
mmol/mol
0.25
1713
15207
663
4856
1.50
16.40
2.3
2.3
2.8
2.8
mg/l
0.13
564
4190
1957
17608
1.55
16.34
4.5
4.0
5.8
5.8
mmol/l
0.43
1791
16145
886
6876
1.45
16.29
4.8
3.7
50.8
91.9
e6/l
1.84
630
4727
557
3951
1.53
15.99
3.6
2.6
5.6
6.6
e6/l
0.94
490
3480
532
3737
1.54
15.97
3.4
2.7
540.3
561.0
mosm/kgh2o
1.16
454
3198
546
3870
1.53
15.69
1.6
1.5
20.0
20.4
nmol/l
0.23
483
3335
734
5529
1.47
15.64
3.9
3.4
7.8
8.0
mmol/l
0.56
648
4746
651
4794
1.49
15.54
5.2
4.7
90.3
90.1
%
0.07
636
4676
368
2389
1.63
15.44
3.1
2.6
22.1
23.2
%
0.83
305
2079
696
5213
1.47
15.19
4.0
3.1
—
—
—
0
0
421
2836
1.58
15.14
6.3
5.0
0.8
0.8
mmol/l
0.34
392
2676
694
5210
1.46
14.91
8.4
7.4
—
—
—
0
0
223
1275
1.82
14.79
3.7
3.3
158.0
186.2
ng/l
0.59
205
1150
2219
20700
1.77
14.78
11.9
9.5
26.5
26.3
u/l
0.16
2146
20006
1136
9331
1.40
14.76
3.4
2.9
106.2
97.6
ug/l
0.64
1055
8713
2227
20803
1.78
14.67
15.5
11.4
—
—
—
0
0
107
474
2.31
14.28
6.1
4.4
7.4
7.4
ph
0.67
92
384
416
2830
1.56
14.27
3.0
2.5
13.1
13.7
umol/l
0.92
385
2622
392
2636
1.58
14.13
1.4
1.4
528.9
500.6
titre
0.09
76
503
1420
12169
1.40
14.07
4.0
3.4
—
—
—
0
0
93
390
2.44
14.04
6.4
4.8
1.4
2.5
mmol/l
5.05
56
252
427
2937
1.55
13.92
2.7
2.8
2.4
2.4
mmol/l
0.15
351
2563
564
4114
1.48
13.89
2.4
2.2
1.1
1.2
mg/l
0.45
410
3044
776
6064
1.41
13.04
3.6
3.3
110.4
50.1
ng/l
0.35
463
3782
716
5536
1.41
12.73
3.3
2.6
56.7
57.1
u/l
0.07
651
5126
254
1579
1.68
12.52
3.6
3.1
9.7
10.3
g/l
2.11
228
1455
210
1240
1.76
12.48
2.5
2.9
66.6
66.5
g/l
0.08
189
1142
608
4588
1.43
12.32
1.7
1.6
1.4
1.4
mmol/l
0.11
524
3928
89
394
2.30
11.94
2.7
2.6
130.0
131.4
g/l
0.18
68
303
153
833
1.89
11.85
2.9
4.1
21.5
21.9
s
0.46
128
748
320
2139
1.57
11.72
1.6
1.5
—
—
—
0
0
139
740
1.93
11.52
14.1
10.6
1.3
1.3
mg/l
0.34
132
706
1479
12973
1.35
11.44
3.9
3.2
40.3
42.9
u/l
0.66
1382
12259
480
3515
1.45
11.32
1.7
1.6
11825633.5
29794833.9
pmol/l
0.65
389
2967
2353
22581
2.10
11.18
24.9
18.2
253.3
256.0
e9/l
1.30
2308
21941
2355
22611
2.11
11.11
25.0
18.3
134.8
135.5
g/l
1.71
2333
22303
2353
22598
2.08
10.88
24.8
18.2
89.9
89.8
fl
0.42
2329
22289
74
315
2.39
10.88
6.0
3.1
—
—
—
0
0
1898
17376
1.41
10.87
21.6
15.3
13.6
13.5
%
1.52
1869
17002
2353
22600
2.07
10.84
24.7
18.1
30.0
30.0
pg
0.14
2329
22290
37
108
3.46
10.82
1.0
1.1
0.3
2.6
nmol/l
—
6
24
2353
22603
2.07
10.79
24.8
18.2
4.5
4.5
e12/l
0.92
2306
21918
365
2555
1.50
10.77
2.3
2.0
—
—
—
0
0
2353
22608
2.06
10.70
25.0
18.3
6.7
6.8
e9/l
0.30
2306
21928
259
1692
1.59
10.44
5.7
3.6
—
—
—
0
0
301
2039
1.54
10.35
3.8
3.6
1.7
1.7
%
0.01
269
1850
261
1721
1.58
10.10
13.5
9.1
8.3
8.1
mmol/l
0.15
255
1662
683
5407
1.36
10.09
1.5
1.4
2.8
1.8
u/ml
0.53
162
1315
313
2150
1.52
10.08
4.3
3.7
7.5
7.3
umol/l
0.05
259
1850
329
2288
1.50
9.99
2.0
1.7
—
—
—
0
0
595
4615
1.38
9.98
4.8
4.2
—
—
—
0
0
77
347
2.26
9.96
3.5
2.8
16.8
16.4
%
0.35
53
183
69
297
2.36
9.92
7.1
3.4
—
—
—
0
0
584
4525
1.38
9.83
3.6
3.4
732.9
300.8
mg/l
0.89
392
2982
892
7373
1.33
9.82
3.5
3.2
—
5.9
—
0
6
1109
9471
1.31
9.60
4.2
3.4
0.0
0.0
estimate
1.08
260
1805
564
4361
1.38
9.59
3.0
2.8
3345.6
5556.9
umol/l
0.71
490
3848
545
4196
1.38
9.50
3.8
3.3
1059.1
1228.5
ng/l
0.53
440
3516
46
166
2.80
9.48
1.1
1.1
176.7
236.3
mg/l
2.00
37
137
93
461
2.06
9.48
8.6
3.8
24.1
24.5
mmol/l
0.34
86
410
47
172
2.76
9.44
1.2
1.2
31.4
35.4
mg/l
0.32
34
137
207
1315
1.63
9.36
2.6
2.3
30.2
21.6
au/ml
—
8
85
90
443
2.07
9.35
2.5
2.4
—
—
—
0
0
209
1333
1.62
9.30
6.3
3.7
1.2
1.2
mmol/l
0.25
176
1141
153
905
1.73
9.06
1.8
1.7
8.7
7.9
u/l
0.39
117
678
190
1193
1.64
9.00
1.4
1.3
34.5
53.2
au/ml
—
5
51
1111
9552
1.30
8.91
4.2
3.4
0.0
0.0
estimate
0.63
262
1789
82
399
2.09
8.80
4.6
3.7
55.5
56.1
%
0.18
82
399
587
4633
1.35
8.64
3.9
3.5
—
—
—
0
0
224
1478
1.57
8.64
3.4
3.2
69.0
69.9
e9/l
0.13
170
1095
1099
9470
1.29
8.53
5.5
4.6
0.0
0.0
estimate
0.50
267
1848
2051
19246
1.40
8.40
19.0
13.6
39.9
39.9
%
0.22
1506
15023
193
1239
1.60
8.37
2.6
1.9
1.5
1.3
g/l
0.55
172
1156
270
1869
1.50
8.35
1.6
1.4
—
—
—
0
0
666
5380
1.33
8.33
3.5
2.7
—
—
—
0
0
258
1771
1.51
8.30
2.6
2.4
33.6
65.8
u/l
0.62
230
1507
417
3139
1.39
8.22
1.4
1.3
25.2
30.8
iu/ml
0.53
118
924
329
2378
1.44
8.15
1.3
1.2
—
—
—
0
0
78
384
2.06
8.14
3.8
3.4
3.8
4.1
e9/l
0.58
78
384
61
273
2.26
8.08
2.7
2.1
1.7
1.7
mmol/l
0.10
61
268
158
975
1.66
8.03
11.1
6.1
9.2
9.3
kpa
0.20
147
923
90
469
1.95
8.03
1.9
2.2
10.4
11.2
mg/l
0.50
80
433
601
4808
1.33
7.99
1.7
1.5
2.1
2.2
g/l
0.17
340
2828
387
2897
1.40
7.86
2.3
2.6
145.8
118.9
ug/g
0.57
305
2301
98
531
1.88
7.79
2.4
2.1
359.6
490.5
mg/l
4.58
90
505
22
58
3.81
7.51
2.4
2.3
17.0
15.6
umol/l
0.18
22
58
838
7059
1.28
7.50
2.1
2.0
—
—
—
0
0
401
3042
1.38
7.50
3.2
2.9
3.7
2.6
e6/l
1.03
223
1641
38
142
2.70
7.40
1.4
1.2
—
—
—
0
0
154
965
1.63
7.39
2.4
2.5
—
—
—
0
0
103
580
1.81
7.27
2.7
2.4
355.5
384.4
ug/l
0.09
90
545
590
4767
1.31
7.21
4.5
4.1
10.8
13.3
mg/mmol
0.23
390
3112
234
1621
1.49
7.21
9.4
5.5
5.1
5.1
kpa
0.02
218
1536
232
1609
1.49
7.10
9.5
5.5
7.4
7.4
ph
0.52
41
143
213
1454
1.51
7.05
1.4
1.3
198.6
266.2
u/ml
0.47
190
1341
207
1406
1.51
7.01
4.4
4.1
0.5
0.6
%
0.49
55
316
414
3190
1.36
6.99
3.1
2.8
0.9
1.1
e6/l
0.26
235
1783
141
878
1.64
6.95
17.6
10.4
—
—
—
0
0
165
1070
1.58
6.88
1.8
1.6
298.6
306.2
mu/l
0.15
145
965
373
2835
1.37
6.87
1.7
1.6
—
—
—
0
0
278
2015
1.43
6.76
1.3
1.2
—
—
—
0
0
265
1906
1.44
6.72
1.4
1.3
—
—
—
0
0
63
310
2.06
6.65
6.4
5.1
395.1
370.3
umol/l
0.70
57
273
12
21
5.73
6.57
1.3
1.2
—
—
—
0
0
388
2992
1.35
6.49
1.3
1.2
5.1
10.7
u/ml
1.66
117
1158
87
484
1.82
6.42
2.6
2.3
18.5
29.3
e6/l
0.27
68
375
87
485
1.82
6.38
2.6
2.3
7288.7
612.7
e6/l
0.47
73
390
92
523
1.79
6.33
1.4
1.4
297.7
303.3
ug/g
0.10
55
297
266
1938
1.42
6.28
13.4
9.1
—
—
—
0
0
245
1765
1.43
6.16
2.9
2.8
0.2
0.2
g/l
0.17
232
1671
193
1328
1.49
6.16
2.5
2.4
3281.7
6407.9
u/l
1.09
60
505
63
320
1.99
6.12
1.8
1.7
—
—
—
0
0
15
35
4.30
6.01
1.4
1.5
—
—
—
0
0
216
1530
1.45
5.95
4.9
4.4
0.9
0.9
%
0.07
70
434
14
32
4.39
5.75
1.3
3.3
—
—
—
0
0
176
1211
1.49
5.64
1.4
1.4
—
—
—
0
0
100
603
1.68
5.63
2.0
1.6
0.2
0.2
g/l
0.05
93
566
1935
18269
1.28
5.61
4.9
4.3
2.7
2.8
mmol/l
2.54
1795
16980
239
1744
1.41
5.60
1.4
1.4
—
—
—
0
0
218
1571
1.42
5.49
2.3
2.2
11.3
12.1
nmol/l
0.66
177
1367
205
1461
1.44
5.48
5.1
4.4
0.0
0.1
%
1.61
66
402
226
1640
1.41
5.47
11.1
8.0
1.4
1.4
mmol/l
0.27
214
1549
17
47
3.63
5.47
1.4
1.0
—
—
—
0
0
17
47
3.63
5.47
1.4
1.0
—
—
—
0
0
17
47
3.63
5.47
1.4
1.0
—
—
—
0
0
195
1379
1.45
5.44
5.2
4.5
0.0
0.6
%
1.01
57
337
83
483
1.74
5.33
2.4
2.1
3.5
3.6
mmol/l
0.38
73
458
95
577
1.67
5.23
3.9
3.3
—
—
—
0
0
26
97
2.70
5.16
2.7
3.3
2.7
2.5
mmol/l
0.11
26
89
42
197
2.15
5.09
1.3
1.7
53.3
59.1
%
0.33
19
138
43
205
2.11
5.01
1.5
1.5
341.1
342.8
pmol/l
0.01
37
155
84
500
1.70
5.00
2.2
1.8
3.4
4.6
iu/l
0.95
27
170
622
5269
1.24
4.92
4.2
3.0
—
—
—
0
0
17
51
3.35
4.87
1.1
1.0
—
—
—
0
0
59
319
1.87
4.85
1.8
1.5
—
—
—
0
0
81
482
1.70
4.83
1.1
1.2
—
—
—
0
0
52
270
1.94
4.82
1.4
1.4
—
—
—
0
0
52
270
1.94
4.82
3.5
3.6
1.4
1.4
%
0.03
41
221
74
430
1.74
4.81
2.3
2.4
39.5
37.8
g/l
1.77
65
372
240
1803
1.37
4.74
13.5
7.8
5.1
5.1
kpa
0.02
234
1718
98
620
1.60
4.63
2.0
1.6
1.2
1.2
g/l
0.12
92
583
238
1803
1.35
4.47
13.6
7.8
13.0
12.7
kpa
0.35
232
1722
23
88
2.63
4.38
1.7
1.2
69.6
69.8
%
—
5
10
43
217
2.00
4.35
1.4
1.5
53.4
50.8
mu/l
0.05
38
193
237
1803
1.35
4.33
13.6
7.8
0.9
0.9
mmol/l
0.04
204
1391
41
206
2.00
4.21
4.0
3.9
—
—
—
0
0
1898
18046
1.23
4.21
4.5
3.9
4.5
4.6
mmol/l
5.03
1760
16897
109
725
1.53
4.18
1.2
1.2
—
—
—
0
0
1885
17918
1.22
4.14
4.4
3.9
1.4
1.4
mmol/l
3.16
1755
16688
37
180
2.07
4.14
1.2
1.1
—
—
—
0
0
191
1419
1.37
4.07
8.2
6.4
24.1
23.9
mmol/l
0.48
184
1338
34
162
2.11
4.02
1.2
1.1
—
—
—
0
0
60
347
1.75
4.02
1.2
1.1
—
—
—
0
0
198
1485
1.36
3.98
15.4
8.3
121.9
122.6
g/l
0.18
193
1429
21
81
2.60
3.96
1.5
1.6
—
—
—
0
0
55
313
1.77
3.90
2.8
4.0
—
—
—
0
0
141
1002
1.43
3.90
8.6
4.6
—
—
—
0
0
278
2197
1.30
3.90
1.3
1.2
—
—
—
0
0
137
969
1.44
3.89
3.5
2.8
—
—
—
0
0
1816
17234
1.20
3.88
4.0
3.6
1.3
1.3
mmol/l
0.18
1675
15986
165
1207
1.39
3.87
1.2
1.2
—
—
—
0
0
40
206
1.96
3.86
3.6
2.9
12.3
10.0
%
0.58
24
144
173
1280
1.38
3.80
10.3
5.8
—
—
—
0
0
75
469
1.62
3.78
1.2
1.2
—
2.5
—
0
43
267
2108
1.30
3.78
8.4
5.8
1.8
1.6
mmol/l
0.28
219
1680
156
1137
1.40
3.75
1.8
1.6
18.6
20.8
iu/l
0.43
119
896
527
4501
1.22
3.75
6.6
4.5
—
—
—
0
0
26
115
2.27
3.70
1.0
1.2
1.0
1.0
ratio
0.05
14
46
31
148
2.11
3.68
3.7
4.3
—
—
—
0
0
23
97
2.38
3.64
2.4
3.3
969.8
1266.1
u/ml
0.30
23
97
65
397
1.65
3.61
1.5
1.7
4621.2
12966.4
e6/l
2.61
44
294
29
136
2.14
3.60
3.8
3.6
362.5
301.5
e6/l
0.22
16
96
44
241
1.84
3.56
3.5
2.9
1.4
1.3
e9/l
0.17
31
163
59
353
1.69
3.54
1.1
1.1
—
—
—
0
0
579
5018
1.20
3.52
5.0
3.6
0.0
0.0
estimate
1.28
262
1778
107
737
1.47
3.52
1.7
1.9
1.6
1.4
g/l
1.19
86
656
110
762
1.46
3.51
1.1
1.1
—
—
—
0
0
8
13
6.16
3.49
1.0
1.3
—
—
—
0
0
93
624
1.51
3.47
3.4
2.7
—
—
—
0
0
268
2141
1.28
3.47
8.5
5.8
7.4
7.4
ph
—
5
10
12
36
3.34
3.47
1.0
1.1
0.6
0.7
umol/24h
—
7
23
205
1580
1.32
3.47
1.3
1.2
113.7
150.9
iu/ml
1.04
71
578
83
546
1.54
3.40
2.2
1.7
—
—
—
0
0
517
4459
1.20
3.29
3.5
3.4
—
—
—
0
0
18
71
2.54
3.28
2.7
3.4
21.2
20.4
mmol/l
0.07
18
66
681
6020
1.18
3.28
2.9
2.5
—
—
—
0
0
203
1580
1.31
3.22
4.5
4.1
—
—
—
0
0
52
310
1.69
3.19
1.4
1.6
—
—
—
0
0
105
736
1.44
3.18
4.6
4.5
0.3
0.3
g/l
0.02
49
386
51
305
1.68
3.11
1.1
1.2
—
—
—
0
0
118
852
1.40
3.05
1.3
1.3
231.0
234.5
miu/ml
0.04
62
428
19
80
2.38
3.05
2.3
2.0
—
—
—
0
0
67
433
1.56
3.01
3.3
3.2
34.1
35.4
umol/l
0.16
60
368
44
255
1.74
3.01
3.6
3.3
—
—
—
0
0
604
5321
1.18
3.00
2.1
2.0
—
—
—
0
0
91
629
1.46
2.98
1.1
1.1
31.6
7.1
u/ml
0.58
11
92
60
381
1.59
2.91
1.6
1.5
0.2
0.4
nmol/l
1.82
54
306
540
4727
1.18
2.89
4.7
4.7
1.9
2.5
ug/l
1.34
479
4242
980
8984
1.15
2.85
4.4
4.0
—
—
—
0
0
483
4192
1.19
2.85
1.7
1.7
—
—
—
0
0
76
512
1.50
2.84
1.2
1.3
—
5.3
—
0
7
230
1854
1.26
2.80
7.7
5.5
5.0
4.8
kpa
1.02
225
1798
49
299
1.65
2.80
1.7
1.6
—
—
—
0
0
15
59
2.55
2.78
3.6
2.7
—
—
—
0
0
16
66
2.43
2.70
1.1
1.1
—
—
—
0
0
6
10
6.01
2.69
2.0
1.1
—
—
—
0
0
64
421
1.53
2.69
2.8
3.8
23.6
49.4
mg/l
1.20
42
345
64
421
1.53
2.69
2.8
3.8
47.3
65.9
mg/l
0.52
42
344
128
961
1.35
2.65
11.1
6.5
25.0
24.3
mmol/l
1.29
121
894
14
320
0.43
2.63
1.4
1.7
—
—
—
0
0
22
106
2.08
2.62
1.5
1.7
5.6
6.6
u/l
0.42
14
91
115
851
1.37
2.61
1.1
1.1
—
—
—
0
0
50
313
1.61
2.60
1.4
1.4
17.3
19.6
u/l
0.21
43
261
11
38
2.90
2.57
1.4
1.9
—
—
—
0
0
13
50
2.61
2.52
1.7
1.6
17.8
16.1
nmol/l
—
5
13
16
69
2.32
2.47
2.8
3.3
153.8
118.8
ug/l
0.28
16
69
15
63
2.39
2.45
2.8
1.9
—
—
—
0
0
39
233
1.68
2.45
2.9
2.3
—
—
—
0
0
34
196
1.74
2.42
3.4
3.0
445.2
555.6
e6/l
0.78
26
165
165
1303
1.28
2.41
2.3
2.7
4.0
4.2
e9/l
0.44
133
1050
12
46
2.61
2.35
1.9
1.2
—
—
—
0
0
38
229
1.67
2.32
1.2
1.3
6.9
6.4
g/l
0.49
27
166
38
229
1.67
2.32
1.2
1.3
2.7
2.6
g/l
0.14
27
164
38
229
1.67
2.32
1.2
1.3
0.4
0.4
g/l
0.42
27
163
63
429
1.48
2.30
1.5
1.4
3.9
4.8
ug/l
0.45
56
396
52
340
1.54
2.29
1.2
1.2
—
—
—
0
0
522
4638
1.16
2.29
2.8
2.4
—
—
—
0
0
12
47
2.56
2.26
1.2
1.1
—
—
—
0
0
33
193
1.72
2.25
3.4
3.0
0.2
0.2
e9/l
0.36
27
165
20
99
2.03
2.25
3.8
3.7
177.1
153.0
umol/l
0.16
13
58
38
232
1.65
2.22
1.3
1.3
—
—
—
0
0
73
516
1.43
2.21
2.3
1.7
93.3
100.8
u/ml
0.23
11
78
43
272
1.59
2.19
2.7
2.5
—
—
—
0
0
26
143
1.82
2.18
1.4
1.6
28.0
33.2
%
—
10
96
11
42
2.62
2.18
1.2
1.2
—
—
—
0
0
268
3145
0.83
2.13
1.5
1.6
—
—
—
0
0
252
2120
1.21
2.11
9.9
7.5
104.9
104.5
mmol/l
0.72
247
2073
42
267
1.58
2.11
1.4
1.3
—
—
—
0
0
179
1455
1.25
2.09
3.7
4.2
5.0
21.7
ug/l
1.91
130
1166
47
308
1.53
2.08
1.6
1.8
69.5
68.2
mmol/l
0.07
39
254
38
237
1.61
2.07
1.1
1.2
—
37.8
—
0
13
5
10
5.00
2.07
4.4
2.4
4.7
4.3
mmol/l
—
5
10
11
44
2.50
2.00
1.5
1.4
49.3
29.6
%
—
6
29
7
21
3.34
1.96
8.4
8.2
—
—
—
0
0
143
1143
1.27
1.94
1.3
1.2
—
—
—
0
0
22
120
1.84
1.92
2.3
2.3
788.8
618.8
ml
0.97
14
76
18
92
1.96
1.89
3.3
1.8
—
—
—
0
0
25
143
1.75
1.88
1.1
1.2
—
—
—
0
0
7
22
3.18
1.87
1.0
1.4
—
—
—
0
0
7
22
3.18
1.87
1.7
1.7
97.0
106.7
ng/l
—
7
22
84
628
1.35
1.87
1.8
1.5
245.7
229.0
u/ml
0.20
50
350
107
829
1.30
1.86
2.1
2.4
—
—
—
0
0
32
197
1.63
1.86
3.2
3.6
—
—
—
0
0
97
742
1.32
1.85
1.6
1.3
—
—
—
0
0
20
107
1.87
1.85
2.4
2.6
135.8
118.6
ng/l
0.33
14
91
17
314
0.54
1.82
1.3
1.2
—
—
—
0
0
39
254
1.54
1.81
1.4
1.3
—
—
—
0
0
32
199
1.61
1.79
1.3
1.2
—
—
—
0
0
7
23
3.05
1.79
1.0
1.1
1.3
1.8
umol/24h
—
7
23
29
177
1.64
1.75
1.0
1.3
—
—
—
0
0
15
74
2.03
1.74
1.1
2.2
—
—
—
0
0
174
1445
1.22
1.71
1.6
1.4
—
—
—
0
0
71
526
1.36
1.70
1.4
1.5
81.1
88.2
titre
—
9
49
14
68
2.06
1.69
1.1
1.1
—
—
—
0
0
0
48
0.00
1.69
0.0
1.5
—
13.5
—
0
35
19
104
1.83
1.66
9.6
7.4
84.2
75.4
mg/l
0.20
14
88
7
25
2.80
1.64
1.3
2.0
—
—
—
0
0
16
83
1.93
1.64
5.8
4.1
—
—
—
0
0
17
91
1.87
1.60
1.0
1.0
4.7
11.8
u/ml
—
5
15
19
106
1.80
1.58
1.1
1.1
1793.4
1599.7
miu/ml
0.38
19
106
156
1293
1.22
1.58
1.2
1.2
382.0
167.9
titre
—
5
40
36
239
1.51
1.56
1.1
1.3
0.5
0.6
nmol/l
0.85
36
229
31
199
1.56
1.56
3.0
2.5
764.7
758.5
e6/l
—
7
50
17
92
1.85
1.55
2.4
2.2
452.2
499.5
min
0.65
11
63
16
85
1.89
1.54
1.6
1.2
—
—
—
0
0
8
33
2.43
1.53
2.1
1.2
—
—
—
0
0
80
617
1.31
1.49
1.7
1.9
4.5
1.9
ug/l
0.41
68
552
50
359
1.40
1.48
1.2
1.7
0.5
0.8
g/l
3.65
35
277
88
1112
0.78
1.48
1.5
1.4
—
—
—
0
0
17
94
1.81
1.46
1.2
1.3
140.8
142.3
nmol/l
0.06
17
94
159
1332
1.21
1.46
2.1
2.3
8.3
7.3
ug/l
0.27
133
1185
25
390
0.64
1.46
4.7
4.2
—
—
—
0
0
26
163
1.60
1.45
3.4
3.2
55.3
53.6
%
0.15
13
112
23
141
1.64
1.41
1.6
1.4
—
—
—
0
0
58
431
1.35
1.41
1.3
1.3
—
—
—
0
0
19
111
1.72
1.38
1.6
1.1
—
—
—
0
0
104
840
1.25
1.37
1.7
1.7
—
—
—
0
0
14
75
1.87
1.34
1.4
1.4
—
—
—
0
0
78
613
1.28
1.30
1.2
1.2
—
—
—
0
0
83
660
1.27
1.27
1.3
1.2
—
—
—
0
0
455
4165
1.11
1.26
3.8
3.6
1.0
1.0
kg/l
0.24
79
637
105
859
1.23
1.25
2.5
2.9
38.4
52.8
u/ml
0.57
99
827
42
303
1.39
1.24
1.4
1.4
—
—
—
0
0
6
25
2.40
1.24
1.0
1.1
—
—
—
0
0
55
416
1.33
1.22
6.5
5.4
—
—
—
0
0
24
155
1.55
1.22
1.5
1.4
113.0
61.9
pmol/l
0.77
13
48
110
1323
0.82
1.22
1.3
1.4
—
—
—
0
0
11
56
1.97
1.21
1.0
12.9
—
—
—
0
0
72
566
1.28
1.21
2.8
3.5
443.1
2584.9
u/ml
0.62
59
483
32
221
1.45
1.20
1.1
1.3
—
—
—
0
0
21
132
1.59
1.20
1.1
1.0
—
—
—
0
0
89
722
1.24
1.16
1.1
1.2
1.3
2.9
u/ml
1.50
43
375
14
80
1.75
1.12
1.2
1.4
—
—
—
0
0
7
30
2.33
1.12
1.4
1.2
—
—
—
0
0
155
1333
1.17
1.12
2.8
2.1
—
—
—
0
0
44
327
1.35
1.12
1.3
1.2
2.4
4.8
u/ml
1.63
16
150
100
827
1.22
1.11
4.8
4.2
1.2
1.3
%
0.25
100
821
7
31
2.26
1.10
1.1
1.1
—
—
—
0
0
133
1131
1.18
1.10
2.9
2.1
—
—
—
0
0
69
549
1.26
1.08
2.8
2.5
—
—
—
0
0
23
152
1.52
1.08
2.4
2.2
8.7
6.5
mmol/l
0.94
15
113
7
32
2.19
1.08
1.1
1.1
—
—
—
0
0
7
32
2.19
1.08
1.1
1.1
—
—
—
0
0
7
32
2.19
1.08
1.1
1.1
—
—
—
0
0
20
128
1.57
1.08
15.1
10.8
0.7
0.6
mmol/l
0.83
20
118
55
703
0.78
1.07
1.3
1.5
—
—
—
0
0
21
137
1.54
1.05
1.1
1.1
—
—
—
0
0
23
154
1.50
1.03
1.3
1.3
926.7
80251.8
e6/l
—
10
103
54
687
0.78
1.03
1.3
1.5
—
—
—
0
0
1830
17891
1.09
1.02
21.4
15.8
333.2
333.3
g/l
0.27
1815
17738
14
83
1.69
1.01
2.3
3.1
7.4
7.4
ph
—
7
27
54
684
0.78
1.00
1.3
1.5
—
—
—
0
0
21
139
1.51
0.99
1.5
1.5
—
—
—
0
0
210
1867
1.14
0.98
22.1
22.0
1.3
1.3
inr
0.14
42
269
121
1037
1.17
0.94
16.8
10.1
92.6
94.1
%
0.78
121
1031
80
660
1.22
0.94
1.1
1.1
4.2
6.4
u/ml
1.00
47
416
7
37
1.89
0.94
2.7
2.6
—
—
—
0
0
19
125
1.52
0.93
1.1
1.1
—
—
—
0
0
78
643
1.22
0.93
1.1
1.1
0.5
1.4
u/ml
1.48
37
357
22
150
1.47
0.92
1.0
1.1
—
—
—
0
0
162
1423
1.15
0.92
2.8
2.0
—
—
—
0
0
54
428
1.27
0.91
1.1
1.1
5.4
7.6
u/ml
0.49
27
212
31
227
1.37
0.90
1.5
1.6
283.3
286.6
mosm/kgh2o
0.50
23
167
27
193
1.40
0.90
2.0
3.0
—
—
—
0
0
163
1437
1.14
0.89
2.8
2.0
—
—
—
0
0
18
119
1.51
0.87
1.2
1.2
—
—
—
0
0
78
648
1.21
0.87
5.0
5.0
—
—
—
0
0
21
145
1.45
0.84
1.4
1.5
—
—
—
0
0
43
543
0.79
0.81
6.6
10.0
—
—
—
0
0
6
32
1.87
0.81
1.5
1.4
—
—
—
0
0
6
32
1.87
0.81
1.5
1.6
—
—
—
0
0
130
1137
1.15
0.81
1.6
1.4
—
—
—
0
0
13
81
1.61
0.81
3.3
2.7
—
—
—
0
0
0
25
0.00
0.79
0.0
1.0
—
—
—
0
0
22
156
1.41
0.78
3.6
2.2
—
—
—
0
0
161
1434
1.13
0.77
2.8
2.0
—
—
—
0
0
0
28
0.00
0.76
0.0
1.0
—
—
—
0
0
9
53
1.70
0.75
1.3
2.3
—
—
—
0
0
51
413
1.24
0.75
1.0
1.1
—
—
—
0
0
28
209
1.34
0.75
1.1
1.1
7.3
9.1
iu/ml
—
8
42
13
83
1.57
0.74
1.0
1.1
—
—
—
0
0
5
24
2.08
0.74
1.2
1.1
—
—
—
0
0
16
108
1.48
0.73
1.8
1.5
1544.7
2030.1
ml
—
6
18
5
25
2.00
0.72
1.2
1.2
—
—
—
0
0
34
263
1.30
0.72
1.3
1.7
—
—
—
0
0
25
185
1.35
0.71
1.2
1.0
—
—
—
0
0
74
628
1.18
0.70
1.0
1.1
3.0
3.2
u/ml
0.03
21
191
9
58
1.55
0.69
8.1
6.0
1.2
1.2
mmol/l
—
9
53
10
61
1.64
0.68
1.5
1.9
—
—
—
0
0
157
1411
1.12
0.67
2.5
2.0
—
—
—
0
0
31
240
1.29
0.67
3.8
4.0
—
—
—
0
0
12
78
1.54
0.65
1.5
1.2
—
—
—
0
0
54
449
1.21
0.64
1.9
2.0
—
—
—
0
0
26
199
1.31
0.62
3.5
4.4
106.5
97.9
u/ml
—
8
57
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
27
209
1.29
0.60
1.0
1.3
—
—
nmol/l
—
0
0
23
174
1.32
0.59
8.7
8.5
12.0
11.5
%
0.31
23
174
8
52
1.54
0.59
6.6
5.8
—
—
—
0
0
125
1387
0.89
0.58
3.7
3.4
—
—
—
0
0
13
89
1.46
0.57
3.5
2.6
—
—
—
0
0
20
149
1.34
0.57
1.4
1.4
5041.0
105323.5
e6/l
—
10
93
132
1195
1.11
0.53
2.9
2.7
—
—
—
0
0
28
222
1.26
0.53
1.2
1.5
—
—
—
0
0
18
134
1.34
0.52
1.5
1.5
—
—
—
0
0
32
392
0.81
0.52
1.3
1.3
—
—
—
0
0
28
223
1.26
0.52
2.4
2.3
—
—
—
0
0
47
397
1.19
0.51
1.0
1.1
2.1
0.4
u/ml
0.37
12
128
25
197
1.27
0.50
1.2
1.2
—
—
—
0
0
20
258
0.77
0.50
3.3
3.1
1.0
0.8
nmol/l
0.85
15
204
33
270
1.22
0.49
1.2
1.2
39.6
42.2
u/l
0.04
28
237
237
2215
1.08
0.49
1.7
1.8
—
—
—
0
0
7
46
1.52
0.48
1.0
1.2
—
—
—
0
0
115
1042
1.11
0.47
17.6
9.9
1.3
1.3
%
0.01
115
1034
7
47
1.49
0.47
1.6
1.4
1.7
3.2
%
—
7
39
54
466
1.16
0.47
1.0
1.1
17.1
6.3
u/ml
0.40
26
218
12
86
1.40
0.44
1.3
1.6
—
—
—
0
0
7
51
1.37
0.44
1.6
1.4
54.4
58.4
%
—
7
41
206
2196
0.93
0.43
1.4
1.3
—
—
—
0
0
11
78
1.41
0.43
2.3
2.8
—
—
—
0
0
8
56
1.43
0.42
1.8
1.5
—
—
—
0
0
5
32
1.56
0.42
1.2
1.3
—
—
—
0
0
45
389
1.16
0.40
1.2
1.1
117.2
1305.7
iu/ml
0.52
13
109
33
388
0.85
0.39
3.0
3.2
27.4
25.2
mg/l
0.10
20
246
20
160
1.25
0.38
2.2
1.9
—
—
—
0
0
35
298
1.18
0.38
2.5
3.3
3.8
19.7
u/ml
0.61
35
271
14
107
1.31
0.37
4.5
6.9
—
—
—
0
0
10
72
1.39
0.36
1.2
1.4
—
—
—
0
0
16
125
1.28
0.36
1.8
2.1
3.5
3.5
mg/l
0.00
16
120
18
143
1.26
0.36
1.0
1.0
—
—
—
0
0
78
858
0.91
0.36
3.2
3.1
—
—
—
0
0
9
122
0.74
0.35
1.2
1.2
—
—
—
0
0
9
124
0.72
0.35
1.1
1.0
—
—
—
0
0
112
1034
1.09
0.35
18.0
10.0
0.7
0.7
%
0.05
112
1027
6
43
1.39
0.35
7.3
5.7
—
—
—
0
0
291
2780
1.05
0.34
2.7
2.9
0.8
0.7
ug/l
0.03
189
1752
6
45
1.33
0.33
1.5
1.3
—
—
—
0
0
44
387
1.14
0.33
2.7
2.4
144.4
116.4
ug/min
0.14
25
237
6
46
1.30
0.33
1.2
1.3
43.0
29.7
%
—
6
40
25
210
1.19
0.32
1.4
1.4
7.2
12.4
mmol/l
—
5
42
20
164
1.22
0.32
1.5
1.5
1570.3
1837.6
e6/l
0.12
14
118
11
143
0.77
0.32
1.1
1.3
—
—
—
0
0
7
99
0.71
0.30
1.1
1.1
171.7
224.0
iu/ml
—
7
99
613
6279
0.97
0.30
1.5
1.6
—
—
—
0
0
23
194
1.19
0.29
1.1
1.2
75.0
194.0
titre
—
6
40
14
173
0.81
0.28
2.6
2.6
—
—
—
0
0
658
6722
0.97
0.27
2.8
2.5
—
—
—
0
0
16
131
1.22
0.27
1.8
2.1
—
1.7
—
0
10
8
67
1.19
0.26
1.3
1.7
—
—
—
0
0
13
160
0.81
0.26
1.0
1.2
—
—
—
0
0
5
71
0.70
0.26
2.0
2.5
—
—
—
0
0
30
265
1.13
0.23
1.4
1.8
—
—
—
0
0
12
97
1.24
0.22
1.4
1.1
—
—
—
0
0
18
153
1.18
0.22
1.6
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
2.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
0.1
—
0
5
0
10
0.00
0.21
0.0
1.0
—
28.5
—
0
5
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
0.2
—
0
6
25
282
0.88
0.20
1.1
1.2
—
—
—
0
0
41
373
1.10
0.20
1.0
1.1
1.8
3.8
u/ml
0.80
13
160
17
145
1.17
0.20
1.0
1.2
122.9
8.6
u/ml
0.43
11
102
19
164
1.16
0.20
3.2
2.8
—
—
—
0
0
335
3259
1.03
0.19
1.8
1.7
—
—
—
0
0
6
53
1.13
0.18
1.3
1.2
—
—
—
0
0
109
1143
0.95
0.18
1.7
1.6
—
—
—
0
0
10
82
1.22
0.17
2.2
2.1
4.0
3.0
ug/l
—
10
72
8
70
1.14
0.16
1.3
1.3
—
—
—
0
0
8
70
1.14
0.16
1.5
2.0
—
—
—
0
0
8
73
1.09
0.15
1.0
1.0
—
—
—
0
0
8
73
1.09
0.15
1.0
1.0
—
0.4
—
0
5
68
717
0.95
0.15
1.4
1.6
—
—
—
0
0
9
81
1.11
0.15
1.6
1.8
—
—
—
0
0
8
98
0.81
0.13
1.0
1.1
—
—
—
0
0
8
99
0.81
0.13
1.0
1.0
—
—
—
0
0
9
106
0.85
0.13
1.2
1.2
—
—
—
0
0
47
446
1.05
0.10
3.6
3.1
9.1
7.4
umol/l
0.30
40
358
20
183
1.09
0.10
1.1
1.1
—
—
—
0
0
24
222
1.08
0.09
1.1
1.2
5.4
2.0
u/ml
—
7
118
5
47
1.06
0.09
1.4
1.3
—
—
—
0
0
13
116
1.12
0.09
1.3
1.2
—
—
—
0
0
46
438
1.05
0.09
1.3
1.1
—
—
—
0
0
14
126
1.11
0.08
2.0
2.5
48.8
42.6
%
—
5
35
6
56
1.07
0.08
1.0
1.2
—
—
—
0
0
5
65
0.77
0.08
1.4
2.4
—
202.4
—
0
8
15
164
0.91
0.08
1.2
1.2
—
—
—
0
0
46
440
1.05
0.08
1.3
1.1
—
—
—
0
0
8
75
1.07
0.07
1.0
1.1
—
—
—
0
0
7
80
0.87
0.07
1.0
1.0
19.4
19.4
mmol/l
—
7
74
48
462
1.04
0.06
3.2
2.2
0.8
0.8
nmol/l
0.26
42
388
38
396
0.96
0.06
1.1
1.2
—
—
—
0
0
29
278
1.04
0.04
2.4
1.9
—
—
—
0
0
29
278
1.04
0.04
2.4
1.9
—
—
—
0
0
29
278
1.04
0.04
2.4
1.9
—
—
—
0
0
29
278
1.04
0.04
2.4
1.9
—
—
—
0
0
16
167
0.96
0.01
1.4
1.3
0.1
0.7
u/ml
—
5
64
19
183
1.04
0.01
1.8
1.6
—
—
—
0
0
23
223
1.03
0.01
1.0
1.2
0.7
5.7
u/ml
—
8
105
15
152
0.99
0.00
2.2
1.5
0.8
1.0
g/l
0.97
15
152
15
152
0.99
0.00
1.4
2.2
—
—
—
0
0
0
8
0.00
0.00
0.0
8.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
0.00
1.2
1.3
308.8
302.1
pmol/l
—
5
36
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
7
74
0.94
0.00
2.6
3.5
—
—
—
0
0
6
61
0.98
0.00
1.2
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
159.9
—
0
7
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
0.00
1.2
1.5
162.4
60.7
mu/l
—
5
42
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
8
87
0.92
0.00
2.0
2.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
8
87
0.92
0.00
1.5
3.2
10.9
10.0
mg/l
—
8
72

Mortality – FinRegistry

Association

Association between endpoint H7_ASTIGMATISM and mortality.

Females

Parameter HR [95% CI] p-value
H7_ASTIGMATISM 1.135 [0.97, 1.33] 0.117
Birth year 0.993 [0.99, 1.0] 0.126

During the follow-up period (1.1.1998 — 31.12.2019), 606 out of 13833 females with H7_ASTIGMATISM died.

Males

Parameter HR [95% CI] p-value
H7_ASTIGMATISM 1.082 [0.89, 1.31] 0.418
Birth year 0.991 [0.98, 1.0] 0.062

During the follow-up period (1.1.1998 — 31.12.2019), 571 out of 12724 males with H7_ASTIGMATISM died.

Mortality risk

Mortality risk for people of age

years, who have H7_ASTIGMATISM.

N-year risk Females Males
1 0.164% 0.179%
5 0.711% 1.335%
10 1.664% 3.468%
15 3.068% 6.704%
20 5.238% 11.303%

Relationships between endpoints

Index endpoint: H7_ASTIGMATISM – Astigmatism

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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