This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Disturbances of smell and taste
R18_DISTU_SMELL_TASTE
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1558 |
4. Check minimum number of eventsNone |
1558 |
5. Include endpointsNone |
1558 |
6. Filter based on genotype QC (FinnGen only) |
1558 |
Control definitions (FinnGen only)
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- R4[0-6]
- Name in latin
- Dysfunctiones olfactus
Similar endpoints
↥List of similar endpoints to
Disturbances of smell and taste
based on the number of shared cases.
Similar with more cases:
- Symptoms and signs involving cognition, perception, emotional state and behaviour
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1558 | 1081 | 477 |
| Unadjusted period prevalence (%) | 0.32 | 0.37 | 0.21 |
| Median age at first event (years) | 57.06 | 56.68 | 57.94 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1410
- Matched controls
- 14100
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R43.8
ICD-10 Finland
Other and unspecified disturbances of smell and taste
819.7
323.0
451
8
R43.0
ICD-10 Finland
Anosmia
6534.3
323.0
894
*
R43.1
ICD-10 Finland
Parosmia
1739.1
159.5
152
*
R42
ICD-10 Finland
Dizziness and giddiness
5.7
92.7
297
631
UDH02
NOMESCO Finland
Rhinopharyngoscopy
5.5
66.3
213
442
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
11.7
61.5
117
108
R01AD09
ATC
mometasone; nasal
2.5
56.8
772
4636
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.5
45.7
176
437
R01AD08
ATC
fluticasone; nasal
2.4
44.8
512
2709
N16
ICPC
Disturbance of smell/taste
226.8
43.1
44
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.3
41.7
167
429
R43
ICD-10 Finland
Disturbances of smell and taste
195.0
37.0
38
*
R01AD12
ATC
fluticasone furoate; nasal
2.2
35.8
494
2789
R43.2
ICD-10 Finland
Parageusia
+∞
35.6
34
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.9
30.1
102
220
DM1CG
NOMESCO Finland
Paranasal sinuses and face area extensive MRI examination with high intensity magnet
69.5
30.0
34
5
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
29.3
446
2579
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
6.6
29.1
77
123
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
23.4
327
1798
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
23.3
503
3253
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
2.0
22.8
324
1791
AA1AD
NOMESCO Finland
CT of head and brain
2.1
21.4
296
1615
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
21.4
381
2289
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
23.5
21.3
30
13
J31.0
ICD-10 Finland
Chronic rhinitis
2.8
21.3
144
548
A02BC05
ATC
esomeprazole; systemic
1.7
20.4
592
4157
UDM02
NOMESCO Finland
Sinoscopy
5.6
20.4
60
111
N02AX02
ATC
tramadol; systemic, rectal
1.7
20.2
589
4139
G44.2
ICD-10 Finland
Tension-type headache
2.3
19.1
196
935
H02AB06
ATC
prednisolone; systemic
1.7
18.9
647
4737
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.1
17.7
101
344
R41.0
ICD-10 Finland
Disorientation, unspecified
21.2
17.3
25
12
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
16.9
558
4002
M54.5
ICD-10 Finland
Low back pain
1.7
16.3
442
2996
N03AX16
ATC
pregabalin; oral
1.8
16.1
329
2044
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.5
15.0
126
541
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
14.8
292
1787
R51.80
ICD-10 Finland
Headache
2.0
14.7
189
990
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
14.4
226
1275
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
14.4
683
5305
N02BE01
ATC
paracetamol; systemic, rectal
1.8
14.3
1192
10658
M03BX02
ATC
tizanidine; oral
1.6
14.2
861
7077
UJF32
NOMESCO Finland
Coloscopy
1.7
13.8
354
2340
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.5
13.7
65
194
M03BC01
ATC
orphenadrine (citrate); systemic
1.7
13.6
312
1998
J01AA02
ATC
doxycycline; systemic
1.6
13.1
1076
9405
R03AC02
ATC
salbutamol; inhalant
1.5
13.0
694
5488
R53
ICD-10 Finland
Malaise and fatigue
1.8
12.3
237
1431
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.7
12.3
320
2117
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.1
12.2
140
699
Z01.2
ICD-10 Finland
Dental examination
1.5
12.1
540
4076
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
12.0
305
2000
A02BC03
ATC
lansoprazole; oral
1.6
11.9
397
2795
N03AX12
ATC
gabapentin; oral
1.8
11.9
208
1217
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.6
11.6
85
340
J33.8
ICD-10 Finland
Other polyp of sinus
4.0
11.6
45
114
N06AX11
ATC
mirtazapine; oral
1.6
11.4
401
2858
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.5
11.4
689
5536
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
11.4
556
4268
Z01.7
ICD-10 Finland
Laboratory examination
2.0
11.4
146
761
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.7
11.4
78
299
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
11.3
140
722
H53.1
ICD-10 Finland
Subjective visual disturbances
2.5
11.2
88
365
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.3
11.1
102
461
M79.6
ICD-10 Finland
Pain in limb
1.5
10.8
459
3409
M01AE02
ATC
naproxen; oral, rectal
1.5
10.7
754
6219
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.5
10.6
82
339
M01AH05
ATC
etoricoxib; oral
1.5
10.5
812
6809
N17
ICPC
Vertigo/dizziness
2.0
10.4
127
650
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
10.4
165
932
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.0
10.3
130
673
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.0
10.2
134
706
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
10.2
144
781
M25.5
ICD-10 Finland
Pain in joint
1.5
10.2
372
2664
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.6
10.2
75
302
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
10.2
536
4156
R41.3
ICD-10 Finland
Other amnesia
7.0
10.1
24
35
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.0
10.1
131
688
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
10.1
315
2168
J01DB01
ATC
cefalexin; oral
1.5
10.1
1090
9744
M01AE03
ATC
ketoprofen; systemic, rectal
1.5
10.1
492
3752
J01CA04
ATC
amoxicillin; systemic
1.5
10.0
1064
9468
N06AX21
ATC
duloxetine; oral
1.9
10.0
140
759
P20
ICPC
Memory disturbance
2.0
9.9
129
677
A02BC02
ATC
pantoprazole; systemic
1.4
9.9
856
7298
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.9
9.8
146
806
R06AX27
ATC
desloratadine; oral
1.5
9.8
345
2444
N06AB10
ATC
escitalopram; oral
1.7
9.8
242
1568
P01AB01
ATC
metronidazole; oral, rectal
1.5
9.7
527
4101
S06.3
ICD-10 Finland
Focal brain injury
5.9
9.7
26
45
DFF00
NOMESCO Finland
Pure tone audiometry
2.1
9.6
113
572
R06.0
ICD-10 Finland
Dyspnoea
1.6
9.5
293
2009
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
9.4
141
778
R01AD11
ATC
triamcinolone; nasal
1.9
9.4
131
705
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
9.3
278
1889
R03BA08
ATC
ciclesonide; inhalant
2.0
9.3
117
607
T90.5
ICD-10 Finland
Sequelae of intracranial injury
6.5
9.3
23
36
S06.0
ICD-10 Finland
Concussion
2.0
9.2
120
629
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.4
9.2
43
130
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.9
9.1
144
815
UDC00
NOMESCO Finland
Ear microscopy
2.1
9.0
99
484
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
9.0
716
5960
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
9.0
592
4759
R07.0
ICD-10 Finland
Pain in throat
2.3
8.9
84
383
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
8.9
433
3279
P76
ICPC
Depressive disorder
2.4
8.9
76
332
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.7
8.9
189
1172
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
8.9
492
3826
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.0
8.9
109
560
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.9
8.8
134
745
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
8.7
819
7000
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
3.3
8.7
43
135
J02AC01
ATC
fluconazole; systemic
1.4
8.7
545
4333
R13
ICD-10 Finland
Dysphagia
2.2
8.7
83
384
L01
ICPC
Neck symptom/complaint
1.7
8.6
171
1038
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
8.6
911
7950
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
2.0
8.5
109
569
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.5
8.5
66
275
M02AA07
ATC
piroxicam; topical
1.4
8.5
474
3686
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.8
8.4
149
873
J01FA10
ATC
azithromycin; systemic
1.4
8.4
762
6458
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
8.4
215
1402
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
8.3
505
3982
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
2.9
8.3
48
168
D01
ICPC
Abdominal pain/cramps general
1.9
8.2
126
703
R51.81
ICD-10 Finland
Facial pain NOS
3.3
8.2
39
120
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.4
8.2
724
6096
G04BD12
ATC
mirabegron; oral
1.8
8.1
127
717
N06AX16
ATC
venlafaxine; oral
1.7
8.1
169
1040
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
2.0
8.1
103
537
H93.1
ICD-10 Finland
Tinnitus
2.1
8.0
86
420
K59.0
ICD-10 Finland
Constipation
2.3
8.0
70
310
TAB00
NOMESCO Finland
Lumbar puncture
2.8
8.0
48
174
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
7.9
569
4614
L03
ICPC
Low back symptom/complaint
1.5
7.9
296
2118
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
7.9
364
2721
J01FA06
ATC
roxithromycin; oral
1.4
7.8
513
4092
J34.2
ICD-10 Finland
Deviated nasal septum
2.3
7.8
69
306
M01AB05
ATC
diclofenac; systemic, rectal
1.4
7.8
885
7745
WX110
NOMESCO Finland
Local anesthesy
1.4
7.8
877
7663
G43.9
ICD-10 Finland
Migraine, unspecified
2.3
7.8
69
307
R06AE07
ATC
cetirizine; oral
1.4
7.8
564
4573
XA800
NOMESCO Finland
Neuropsychological investigation
3.0
7.7
44
151
L08
ICPC
Shoulder symptom/complaint
1.6
7.7
238
1630
C07AA05
ATC
propranolol; systemic
1.6
7.7
238
1630
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.5
7.3
54
219
R52.2
ICD-10 Finland
Other chronic pain
2.7
7.3
47
177
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.7
7.2
153
949
K02.1
ICD-10 Finland
Caries of dentine
1.4
7.1
695
5894
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
7.1
333
2487
J33.0
ICD-10 Finland
Polyp of nasal cavity
2.9
7.1
41
145
R21
ICPC
Throat symptom/complaint
1.6
7.0
211
1434
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
7.0
605
5028
R50.9
ICD-10 Finland
Fever, unspecified
1.7
7.0
157
987
R05
ICD-10 Finland
Cough
1.5
7.0
233
1618
M70.6
ICD-10 Finland
Trochanteric bursitis
1.6
7.0
168
1081
M01AC06
ATC
meloxicam; systemic, rectal
1.4
6.9
471
3761
R20.2
ICD-10 Finland
Paraesthesia of skin
2.0
6.9
82
415
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.9
6.9
100
547
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.6
6.9
203
1371
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.4
6.9
584
4834
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.6
6.9
173
1122
F51.0
ICD-10 Finland
Nonorganic insomnia
1.7
6.9
148
921
M54.2
ICD-10 Finland
Cervicalgia
2.0
6.8
88
463
S18
ICPC
Laceration/cut
1.4
6.8
501
4051
SPAT1043
SPAT
Audiometry
1.8
6.8
126
748
ZXA05
NOMESCO Finland
Left side
1.4
6.8
305
2257
N06AA09
ATC
amitriptyline; systemic
1.7
6.8
126
750
Z2221
NOMESCO Finland
Medical doctor
1.4
6.7
332
2499
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.9
6.7
99
547
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
4.3
6.7
23
54
G43.3
ICD-10 Finland
Complicated migraine
4.7
6.7
21
45
K80
ICPC
Cardiac arrhythmia NOS
1.9
6.7
93
503
M01AX17
ATC
nimesulide; oral
1.4
6.7
309
2300
A04
ICPC
Weakness/tiredness general
1.7
6.6
133
812
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
6.6
226
1581
XF402
NOMESCO Finland
ECG with work load test
1.7
6.6
131
799
K30
ICD-10 Finland
Functional dyspepsia
1.7
6.6
134
821
G04CA02
ATC
tamsulosin; oral
1.6
6.6
189
1268
R01AD05
ATC
budesonide; nasal
1.8
6.5
108
618
SPAT1053
SPAT
Memory test
1.6
6.5
151
958
R25.1
ICD-10 Finland
Tremor, unspecified
2.8
6.5
38
136
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.8
6.4
109
633
G20
ICD-10 Finland
Parkinson disease
2.9
6.4
35
121
G47.3
ICD-10 Finland
Sleep apnoea
1.5
6.4
245
1756
H81.3
ICD-10 Finland
Other peripheral vertigo
3.3
6.4
29
88
WZA90
NOMESCO Finland
Other doctors statement
1.5
6.3
271
1982
A06AC51
ATC
ispaghula, combinations; systemic
2.2
6.3
60
280
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
6.3
199
1365
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.4
6.3
49
208
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.5
6.3
45
182
A11
ICPC
Chest pain NOS
1.9
6.3
89
484
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
6.3
91
500
DM1CM
NOMESCO Finland
Paranasal sinuses extensive MRI examination with 3 Tesla magnet
+∞
6.3
6
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.0
6.2
75
385
J01MA02
ATC
ciprofloxacin; systemic
1.4
6.2
451
3628
D11
ICPC
Diarrhoea
1.7
6.2
122
740
H02
ICPC
Hearing complaint
1.6
6.1
138
870
J01FA09
ATC
clarithromycin; systemic
1.4
6.1
397
3137
S80.1
ICD-10 Finland
Contusion of other and unspecified parts of lower leg
2.6
6.1
40
154
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
6.1
501
4108
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.4
6.1
323
2461
R03DC03
ATC
montelukast; oral
1.5
6.0
196
1355
SPAT1212
SPAT
Extensive examination of musculoskeletal system
1.8
6.0
95
540
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: R18_DISTU_SMELL_TASTE – Disturbances of smell and taste
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).