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Seropositive rheumatoid arthritis, strict definition

DOID EFO Endpoint Browser PheWeb

RHEUMA_SEROPOS_STRICT

Felty's syndrome: Felty syndrome (FS), also known as ''super rheumatoid'' disease, is a severe form of rheumatoid arthritis (RA), characterized by a triad of RA, splenomegaly and neutropenia, resulting in susceptibility to bacterial infections.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

  • RHEUMA_SEROPOS_OTH_ICD10
11802

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • KELA reimbursements: KELA codes — ANY
  • KELA reimbursements: ICD-10 — M05

1 out of 7 registries used, show all original rules.

6333

4. Check minimum number of events

None

6333

5. Include endpoints

None

6333

6. Filter based on genotype QC (FinnGen only)

6333

Control definitions (FinnGen only)

Control conditions
not RHEUMA_SEROPOS_OTH_ICD10

Extra metadata

First used in FinnGen datafreeze
DF3

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 31325 21200 9976
Only index persons 29603 20324 9279
Unadjusted period prevalence (%)
Whole population 0.50 0.61 0.28
Only index persons 0.62 0.75 0.35
Median age at first event (years)
Whole population 59.60 59.01 60.86
Only index persons 59.06 58.50 60.29

-FinnGen-

Key figures

All Female Male
Number of individuals 6333 4420 1913
Unadjusted period prevalence (%) 1.31 1.51 0.84
Median age at first event (years) 56.90 55.20 60.84

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
5569
Matched controls
55691
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
16.9
323.0
610
402
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
101.8
323.0
1833
267
L04AB01
ATC
etanercept; parenteral
81.8
323.0
872
126
L04AB04
ATC
adalimumab; parenteral
37.3
323.0
754
233
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
+∞
323.0
5569
2268
L04AA13
ATC
leflunomide; oral
109.4
323.0
1609
206
M01CB01
ATC
sodium aurothiomalate; parenteral
156.2
323.0
803
60
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
220.8
323.0
4888
1750
L88
ICPC
Rheumatoid/seropositive arthritis
59.1
323.0
1941
499
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
9.3
323.0
1550
2210
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
41.4
323.0
2763
1293
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
43.2
323.0
2926
1389
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
47.6
323.0
619
146
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
42.0
323.0
474
123
P01BA02
ATC
hydroxychloroquine; oral
198.8
323.0
4744
1562
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
71.1
323.0
1562
304
NH3EA
NOMESCO Finland
Feet X-ray examination with load
17.5
323.0
561
355
H02AB06
ATC
prednisolone; systemic
12.2
323.0
4793
18726
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
18.6
323.0
674
409
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
93.7
323.0
1687
257
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
13.1
323.0
1923
2158
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
1772.4
323.0
1883
16
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
4503599627370496.0
323.0
5444
31
A07EC01
ATC
sulfasalazine; oral, rectal
82.3
323.0
3849
1473
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
5.7
323.0
3559
13195
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
69.8
323.0
2017
449
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
18.6
323.0
609
366
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
291.6
323.0
645
25
M13.9
ICD-10 Finland
Arthritis, unspecified
6.1
320.4
957
1818
L04AA24
ATC
abatacept; parenteral
265.3
319.8
325
13
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
15.9
307.3
518
357
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
90.6
298.2
332
39
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.8
291.9
3113
17211
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
9.0
283.2
636
787
H02AB07
ATC
prednisone; oral
3.7
271.8
1398
4578
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
56.1
249.8
298
56
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
19.5
248.1
386
212
L04AA17
ATC
[U] adalimumab; parenteral
359.7
242.4
243
7
M06
ICD-10 Finland
Other rheumatoid arthritis
83.2
239.0
269
34
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
12.8
229.6
423
354
L04AB06
ATC
golimumab; parenteral
39.8
228.4
291
77
M01CB03
ATC
auranofin; oral
53.0
222.5
268
53
L04AA01
ATC
[U] ciclosporin; systemic
17.2
218.5
355
219
TNG10
NOMESCO Finland
Puncture of knee
21.6
211.4
317
155
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
9.9
209.1
441
481
L04AA11
ATC
[U] etanercept; parenteral
127.8
205.9
221
18
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
44.3
191.1
238
56
L04AC07
ATC
tocilizumab; parenteral
204.1
190.4
197
10
R4120
NOMESCO Finland
Occupational therapy
4.8
188.4
693
1614
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
14.3
187.8
329
244
3006
Kela drug reimbursment
Baricitinib
329.1
187.5
189
6
L04AB05
ATC
certolizumab pegol; parenteral
57.3
180.9
215
39
293
Kela drug reimbursment
Baricitinib
316.1
180.2
182
6
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.3
179.5
731
1880
NDG30
NOMESCO Finland
Fusion of wrist, total
73.1
173.0
198
28
L04AA37
ATC
baricitinib; oral
259.6
172.6
176
7
L04AX01
ATC
azathioprine; systemic
5.8
167.9
508
943
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
6.1
166.0
484
857
291
Kela drug reimbursment
Tofacitinib
99.0
165.2
182
19
ZX140
NOMESCO Finland
Intra articular
22.9
164.8
242
110
WZA10
NOMESCO Finland
Long statement of health and health related matters
13.7
157.9
281
215
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
22.4
156.8
232
108
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
25.2
156.3
223
92
M25.5
ICD-10 Finland
Pain in joint
2.3
151.2
1966
10804
NDL52
NOMESCO Finland
Tenosynovectomy of hand
27.9
148.0
205
76
L04AA29
ATC
tofacitinib; oral
75.4
147.4
168
23
XX9XE
NOMESCO Finland
Other ultrasound examination
17.5
145.5
234
139
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
9.6
144.2
307
337
ZX120
NOMESCO Finland
Intravenous
3.3
142.8
816
2759
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
22.7
132.6
195
89
L01CB
ATC
Podophyllotoxin derivatives
413.1
122.2
122
*
3005
Kela drug reimbursment
Tofacitinib
75.1
122.0
139
19
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
7.8
120.9
292
394
TND10
NOMESCO Finland
Joint puncture, wrist or finger joint
55.2
117.3
140
26
M05BA04
ATC
alendronic acid; oral
3.1
116.5
708
2477
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
47.1
112.4
138
30
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
12.9
111.5
203
163
M12.3
ICD-10 Finland
Palindromic rheumatism
55.8
110.0
131
24
RT272
NOMESCO Finland
NA
40.7
110.0
139
35
M01AH05
ATC
etoricoxib; oral
1.9
103.9
3443
25951
M01AH01
ATC
celecoxib; oral (coxibs)
2.2
102.2
1259
6521
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
12.1
102.0
191
163
1XC02
NOMESCO Finland
NA
18.2
101.9
161
91
A02BC02
ATC
pantoprazole; systemic
1.9
98.3
3768
29539
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
5.8
97.7
290
519
NG1DA
NOMESCO Finland
X-ray of knees
7.3
93.5
235
336
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
4.0
91.4
392
1034
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.5
90.4
817
3609
M01AC06
ATC
meloxicam; systemic, rectal
1.8
88.1
2270
15398
TNC11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in elbow joint
38.1
87.6
112
30
M13.0
ICD-10 Finland
Polyarthritis, unspecified
9.6
85.5
180
193
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.1
85.3
515
1777
L04AC14
ATC
sarilumab; systemic
799.8
80.6
79
*
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
18.9
79.8
124
67
NDF10
NOMESCO Finland
Synovectomy of wrist
82.3
79.2
89
11
NH3AE
NOMESCO Finland
Feet ultrasound examination
38.8
77.8
99
26
L20
ICPC
Joint symptom/complaint NOS
4.0
77.8
328
850
SPAT1202
SPAT
Intra-articular injection
4.1
76.5
313
789
H02AB04
ATC
methylprednisolone; systemic
2.1
75.2
958
4953
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.4
72.2
382
1194
9522
FHL
Synovectomy
113.0
72.0
78
7
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
10.5
71.9
144
141
RK210
NOMESCO Finland
NA
37.0
70.9
91
25
RT310
NOMESCO Finland
NA
68.4
70.4
81
12
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
4.0
69.9
297
774
L04AD01
ATC
ciclosporin; systemic
6.1
69.8
199
338
TNH10
NOMESCO Finland
Joint puncture, ankle joint or foot joint
63.2
69.6
81
13
M05BA07
ATC
risedronic acid; oral
3.9
67.9
294
779
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
66.9
1241
7387
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.8
66.4
451
1673
ND1AE
NOMESCO Finland
Wrist ultrasound examination
21.9
65.8
97
45
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.6
65.8
522
2126
NF1AA
NOMESCO Finland
Hip X-ray examination
2.5
65.7
569
2432
RK220
NOMESCO Finland
NA
19.2
64.9
100
53
7140B
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SERONEGATIVA]
37.8
64.2
82
22
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
4.2
62.3
250
618
NDB78
NOMESCO Finland
Prosthetic replacement of several of finger or metacarpal
133.5
62.0
66
5
R4110
NOMESCO Finland
Physiotherapy
1.7
61.7
1508
9782
D06BB04
ATC
podophyllotoxin; topical
3.3
61.7
327
1021
WX320
NOMESCO Finland
Spinalanesthesy
1.8
61.3
1303
8085
NB2AT
NOMESCO Finland
Intra artrial injection of shoulder with ultrasound guidance
6.9
61.2
158
235
M05.0
ICD-10 Finland
Felty syndrome
159.2
60.0
63
*
NDF60
NOMESCO Finland
Operation for osteochondritis of a joint of hand,v
31.2
60.0
80
26
M06.3
ICD-10 Finland
Rheumatoid nodule
94.0
58.9
65
7
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
56.9
2328
17314
RT271
NOMESCO Finland
NA
35.2
56.4
73
21
WX204
NOMESCO Finland
Axillary plexus blockaced
3.8
56.2
248
668
M05.3
ICD-10 Finland
Rheumatoid arthritis with involvement of other organs and systems
89.6
55.9
62
7
298
Kela drug reimbursment
NA
553.5
55.7
55
*
H02AB08
ATC
triamcinolone; systemic
17.2
55.1
88
52
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.2
54.7
583
2752
M01AH02
ATC
rofecoxib; oral
2.0
54.6
819
4472
R4180
NOMESCO Finland
Podiatric therapy
8.0
53.1
124
159
3029
Kela drug reimbursment
Upadacitinib
185.1
53.0
55
*
NHG22
NOMESCO Finland
Fusion of subtalar joint
12.3
52.9
97
80
9503
FHL
Tendon or tendon sheath cleansing surgery (tenosynovectomy)
22.0
51.8
76
35
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
50.5
2149
15985
ZXA00
NOMESCO Finland
Right side
1.6
50.1
1492
10126
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
50.1
1126
7046
9256
FHL
Synovectomy (knee 9311)
92.6
49.9
55
6
M05BX04
ATC
denosumab; parenteral
2.8
49.8
349
1314
M17.5
ICD-10 Finland
Other secondary gonarthrosis
6.2
49.1
137
227
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
4.9
49.0
167
351
S18
ICPC
Laceration/cut
1.5
48.6
2204
16595
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
48.6
2459
18993
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
10.0
48.6
99
101
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
16.0
48.2
79
50
NDB60
NOMESCO Finland
Prosthetic replacement of MCP joint of finger
89.2
47.9
53
6
NHM99
NOMESCO Finland
Other operation on fascia, ganglion, synovial sheath or bursa of ankle or foot
9.9
47.3
97
100
L11
ICPC
Wrist symptom/complaint
2.3
46.6
474
2183
NHG82
NOMESCO Finland
Fusion of other tarsal joint
6.8
46.1
119
178
N02AX02
ATC
tramadol; systemic, rectal
1.5
45.4
2225
16971
TQW40
NOMESCO Finland
Remowal of suture of skin
2.3
45.1
443
2004
R1250
NOMESCO Finland
Evaluation of functional capability
4.2
44.9
179
440
M01AE02
ATC
naproxen; oral, rectal
1.5
44.4
3000
24491
RS221
NOMESCO Finland
NA
5.3
44.1
138
264
M01CC01
ATC
penicillamine; oral
52.4
43.6
52
10
WZC30
NOMESCO Finland
Teaching
1.9
43.1
760
4371
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.4
42.5
393
1723
N02BE01
ATC
paracetamol; systemic, rectal
1.6
42.2
4678
42402
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
2.0
41.6
597
3183
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.7
41.5
296
1126
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.1
41.5
541
2776
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
41.5
1936
14521
WX203
NOMESCO Finland
Infraclavicular plexus blockade
4.0
41.4
172
440
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
30.8
41.4
55
18
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.9
41.2
176
461
TNB10
NOMESCO Finland
Joint puncture, shoulder joint
21.6
40.9
60
28
J01DB01
ATC
cefalexin; oral
1.6
40.9
4356
38856
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
4.8
40.8
140
297
R5120
NOMESCO Finland
Preparation of an aid
3.7
40.8
186
516
NCF10
NOMESCO Finland
Synovectomy of elbow joint, open
53.8
40.5
48
9
M05BA06
ATC
ibandronic acid; systemic
3.9
40.4
171
445
K71
ICPC
Rheumatic fever/heart disease
400.4
40.1
40
*
RT171
NOMESCO Finland
NA
28.7
39.9
54
19
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
6.9
39.9
102
151
M19.2
ICD-10 Finland
Other secondary arthrosis
5.8
39.8
115
200
L04AA44
ATC
upadacitinib; oral
141.0
39.8
42
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.8
39.4
771
4578
R2110
NOMESCO Finland
Giving the first information
2.2
38.9
426
2025
NDF68
NOMESCO Finland
Operation for osteochondritis of several joints of hand, open
74.0
38.9
44
6
J99.0*M05.1
ICD-10 Finland
Rheumatoid lung disease
+∞
38.6
37
*
NDG74
NOMESCO Finland
Fusion of first IP joint
19.5
38.2
58
30
M01AX17
ATC
nimesulide; oral
1.6
38.0
1363
9578
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.2
37.7
210
680
A02BC03
ATC
lansoprazole; oral
1.5
37.3
1557
11323
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
2.2
37.1
410
1956
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
6.0
37.0
105
179
M06.4
ICD-10 Finland
Inflammatory polyarthropathy
16.0
36.8
60
38
J01FF01
ATC
clindamycin; systemic
1.5
36.5
1413
10092
9284
FHL
Wrist ossification surgery
80.7
35.8
40
5
ZZH31
NOMESCO Finland
Bone allograft, small pieces
7.3
35.8
87
120
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
35.3
897
5747
M01AX01
ATC
nabumetone; oral
2.5
35.1
291
1203
M01AB55
ATC
diclofenac, combinations; oral
2.1
34.8
421
2087
RJ410
NOMESCO Finland
NA
12.8
34.7
62
49
TGC00
NOMESCO Finland
Bronchial lavation
3.4
34.7
178
543
L17
ICPC
Foot/toe symptom/complaint
1.5
34.6
1313
9312
ZXA05
NOMESCO Finland
Left side
1.5
34.5
1327
9438
NDL66
NOMESCO Finland
Transposition of tendon of wrist or hand, other tendon
13.1
34.5
61
47
RF120
NOMESCO Finland
NA
5.1
34.1
111
223
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
3.0
34.1
203
689
NHF80
NOMESCO Finland
Operation for debridement of toe joint, open
34.1
34.0
44
13
NF2AT
NOMESCO Finland
Injection to hip joint with ultrasound guidance
10.4
34.0
67
65
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
5.6
33.9
101
183
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.4
33.9
308
1339
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.7
33.6
248
961
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.1
33.6
406
2011
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
3.3
33.4
177
554
NCM20
NOMESCO Finland
Excision of synovial ganglion of elbow or forearm
15.0
33.0
55
37
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.0
32.9
201
693
RT231
NOMESCO Finland
NA
90.6
32.7
36
*
P01BA01
ATC
chloroquine; systemic
9.4
32.7
68
73
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
2.4
32.2
284
1214
RK250
NOMESCO Finland
NA
10.1
32.0
64
64
L84
ICD-10 Finland
Corns and callosities
2.9
32.0
206
736
ND2AE
NOMESCO Finland
Hand and fingers ultrasound examination
16.6
31.9
51
31
4AA24
NOMESCO Finland
NA
165.9
31.7
33
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
31.7
388
1933
TNF11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in hip joint
22.7
31.3
45
20
RJ511
NOMESCO Finland
NA
21.1
31.3
46
22
SPAT1229
SPAT
Assessment of need for aid
2.0
31.2
426
2217
L12
ICPC
Hand/finger symptom/complaint
1.7
30.9
729
4558
RS222
NOMESCO Finland
NA
5.0
30.7
101
206
RF410
NOMESCO Finland
NA
4.8
30.6
105
224
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
30.5
533
3036
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
30.5
596
3523
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
4.7
30.2
104
223
NDC40
NOMESCO Finland
Secondary prosthetic replacement in of joint of finger or metacarpal
83.1
29.7
33
*
-1
NOMESCO Finland
NA
1.4
29.7
1584
12011
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
3.5
29.6
141
407
9272
FHL
Metatarsophalangeal joint resection
17.8
29.6
46
26
S97
ICPC
Chronic ulcer skin
2.3
29.5
279
1238
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.5
29.3
239
980
M43.4
ICD-10 Finland
Other recurrent atlantoaxial subluxation
57.0
29.1
34
6
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
28.9
1406
10455
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.1
28.9
356
1778
NDG76
NOMESCO Finland
Fusion of DIP joint
6.1
28.8
79
130
N05.8
ICD-10 Finland
Unspecified nephritic syndrome, other
150.8
28.7
30
*
RF420
NOMESCO Finland
NA
4.2
28.6
110
264
M13.8
ICD-10 Finland
Other specified arthritis
5.6
28.4
84
152
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
2.7
27.8
199
759
NCB20
NOMESCO Finland
Primary total prosthetic replacement of elbow joint
32.9
27.7
36
11
RS121
NOMESCO Finland
NA
7.6
27.7
65
86
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
2.2
27.2
281
1299
NG2CA
NOMESCO Finland
X-ray of patella with specialised projection
9.4
27.1
56
60
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
3.3
26.8
137
419
4AC07
NOMESCO Finland
NA
97.2
26.7
29
*
RJ421
NOMESCO Finland
NA
10.1
26.1
52
52
L34
ICPC
Musculoskeletal, Blood test
25.9
26.1
36
14
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
23.3
26.0
37
16
R50.9
ICD-10 Finland
Fever, unspecified
1.7
25.7
641
4060
RT350
NOMESCO Finland
NA
21.9
25.6
37
17
NDM99
NOMESCO Finland
Other operation on fascia, ganglion, synovial sheath or bursa of wrist or hand
7.4
25.5
61
83
RJ512
NOMESCO Finland
NA
15.1
25.5
42
28
QDH05
NOMESCO Finland
Correction of deformity of toe nail
13.4
25.4
44
33
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.3
25.3
133
415
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
25.1
2107
17190
M66.0
ICD-10 Finland
Rupture of popliteal cyst
4.0
25.0
103
264
318
Kela drug reimbursment
Teriparatide
7.5
25.0
59
79
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
2.7
24.9
178
680
9531
FHL
Arthrodesis of the hand joint
10.5
24.7
48
46
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
5.3
24.7
76
145
J01MA12
ATC
levofloxacin; systemic
1.5
24.2
877
6091
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
3.6
24.1
112
318
ACC51
NOMESCO Finland
Release of median nerve
1.9
23.9
395
2202
9527
FHL
Alloarthroplasty, implant or endoprosthesis
87.1
23.7
26
*
L28
ICPC
Limited function/disability (L)
1.6
23.5
754
5088
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
2.6
23.4
182
728
NG1EA
NOMESCO Finland
Knee X-ray examination with wrench
3.7
23.4
104
285
NDG77
NOMESCO Finland
Other excision, reconstruction or fusion of joint of first finger
12.9
23.3
41
32
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
23.3
517
3167
RJ411
NOMESCO Finland
NA
7.0
23.1
57
82
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
2.1
23.0
254
1212
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
22.9
633
4114
ZX100
NOMESCO Finland
Oral
3.8
22.9
99
265
NDG20
NOMESCO Finland
Fusion of wrist, partial
6.3
22.8
61
98
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
2.1
22.7
275
1365
Z71.8
ICD-10 Finland
Other specified counselling
1.4
22.5
1120
8298
L95
ICPC
Osteoporosis
2.4
22.5
189
788
M01AE01
ATC
ibuprofen; systemic, rectal
1.5
22.2
4741
44414
RJ210
NOMESCO Finland
NA
11.5
22.1
41
36
M05.2
ICD-10 Finland
Rheumatoid vasculitis
52.2
22.1
26
5
L50
ICPC
Musculoskeletal, Medication/prescr/renewal
7.7
22.0
51
67
H05AA02
ATC
teriparatide; parenteral
7.2
21.9
53
74
NHB10
NOMESCO Finland
Primary partial prosthetic replacement of ankle joint
20.1
21.6
32
16
RT274
NOMESCO Finland
NA
15.3
21.5
35
23
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
21.3
584
3785
RJ190
NOMESCO Finland
NA
13.9
21.2
36
26
7148X
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Other specified inflammatory polyarthropathies
18.9
21.2
32
17
L99
ICPC
Musculoskeletal disease other
3.0
21.2
125
425
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.6
21.1
432
6610
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
21.1
1955
16067
NF1DA
NOMESCO Finland
X-ray of hips
2.8
21.0
139
509
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.8
20.9
370
2113
B01AB05
ATC
enoxaparin; parenteral
1.4
20.8
1495
11800
M17.4
ICD-10 Finland
Other secondary gonarthrosis, bilateral
7.2
20.7
50
70
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
20.7
1473
11606
4AB02
NOMESCO Finland
NA
10.9
20.6
39
36
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
2.8
20.6
132
474
RF212
NOMESCO Finland
NA
8.4
20.6
45
54
J05AB11
ATC
valaciclovir; oral
1.6
20.4
649
4361
M20.1
ICD-10 Finland
Hallux valgus (acquired)
1.7
20.4
461
2833
9289
FHL
Other measure in this category
20.1
20.3
30
15
NDL40
NOMESCO Finland
Repair of tendon of finger with transplant
8.5
19.8
43
51
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
7.5
19.6
46
62
M08.8
ICD-10 Finland
Other juvenile arthritis
105.4
19.6
21
*
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
2.3
19.5
181
795
M16.7
ICD-10 Finland
Other secondary coxarthrosis
4.8
19.5
65
137
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
19.3
835
6001
NH1AD
NOMESCO Finland
Ankle and foot CT
2.9
19.1
119
420
QXA20
NOMESCO Finland
Skin abrasion, unspecified location
8.6
19.1
41
48
NBB10
NOMESCO Finland
Primary partial prosthetic replacement of humero-scapular joint not using cement, other or unspecified
5.5
18.9
56
103
B02.9
ICD-10 Finland
Zoster without complication
1.9
18.9
287
1551
M13.1
ICD-10 Finland
Monoarthritis, not elsewhere classified
4.0
18.8
76
193
J99.0
ICD-10 Finland
Rheumatoid lung disease
190.6
18.5
19
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.9
18.5
272
1457
Z50.1
ICD-10 Finland
Other physical therapy
1.9
18.4
280
1517
H16.0
ICD-10 Finland
Corneal ulcer
2.1
18.3
218
1075
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
2.5
18.2
150
622
QDH
NOMESCO Finland
Operations on toe nails
25.1
18.2
25
10
9283
FHL
Subtalar joint ossification surgery (or triple)
19.4
18.1
27
14
NC1AE
NOMESCO Finland
Elbow ultrasound examination
19.4
18.1
27
14
SPAT1255
SPAT
Intravenous administration of medicine
1.8
18.1
320
1822
J01CA04
ATC
amoxicillin; systemic
1.3
18.1
4096
37775
NHG20
NOMESCO Finland
Fusion of talocrural joint
5.8
18.1
51
89
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.8
17.7
340
1992
NH1FA
NOMESCO Finland
Weight-bearing X-ray of ankle
4.4
17.6
63
143
NHF70
NOMESCO Finland
Operation for debridement of joint of foot, open
36.8
17.6
22
6
J47
ICD-10 Finland
Bronchiectasis
2.9
17.5
107
374
115
Kela drug reimbursment
Breast cancer
0.5
17.5
166
3082
H26.3
ICD-10 Finland
Drug-induced cataract
5.8
17.5
49
85
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
1.8
17.4
294
1651
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.0
17.4
224
1142
WZA00
NOMESCO Finland
Short statement of of health and health related matters
1.9
17.2
277
1528
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
6.8
17.2
43
64
WW200
NOMESCO Finland
Immunization
2.4
17.1
143
600
L02BG04
ATC
letrozole; oral
0.5
17.0
101
2174
WX202
NOMESCO Finland
Supraclavicular plexus blockade
3.3
16.9
84
254
RF210
NOMESCO Finland
NA
2.3
16.9
153
665
NHK68
NOMESCO Finland
Shortening or lengthening osteotomy of ankle or foot
6.0
16.9
46
77
ZXA10
NOMESCO Finland
Bilateral
1.4
16.8
870
6456
L45
ICPC
Musculoskeletal, Observ/health educat/advice/diet
21.9
16.8
24
11
NBF15
NOMESCO Finland
Humeroscapular synovectomy, arthroscopic
8.4
16.6
36
43
WZA90
NOMESCO Finland
Other doctors statement
1.4
16.6
1050
8066
TNH33
NOMESCO Finland
Custom moulded brace, ankle or foot
3.1
16.6
90
291
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.5
16.6
577
3948
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
3.0
16.6
98
336
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
16.4
514
3435
RS224
NOMESCO Finland
NA
6.7
16.3
41
62
A28
ICPC
Limited function/disability NOS
1.5
16.2
629
4410
M02AA07
ATC
piroxicam; topical
1.3
16.0
1812
15158
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
15.9
489
3252
M79.6
ICD-10 Finland
Pain in limb
1.3
15.8
1712
14235
N02BA01
ATC
acetylsalicylic acid; systemic, rectal
60.2
15.7
18
*
SPAT1153
SPAT
Removal of sutures
1.3
15.7
1538
12608
NHF15
NOMESCO Finland
Synovectomy of ankle, arthroscopic
11.2
15.7
29
26
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.6
15.7
440
2862
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
15.6
2507
21902
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.8
15.5
263
1480
L04AA14
ATC
[U] anakinra; parenteral
160.4
15.5
16
*
RF430
NOMESCO Finland
NA
8.5
15.4
33
39
NDG71
NOMESCO Finland
Arthrodes of first MP joint
8.9
15.4
32
36
M50.8
ICD-10 Finland
Other cervical disc disorders
5.5
15.3
45
83
A60
ICPC
General and Unspecified, Result test/procedure
2.0
15.3
204
1055
A02BA02
ATC
ranitidine; systemic
1.4
15.3
929
7083
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
15.2
3067
27500
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.0
15.2
184
917
N02AA05
ATC
oxycodone; systemic
1.5
15.2
623
4417
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
2.6
15.2
114
452
M95.8
ICD-10 Finland
Other specified acquired deformities of musculoskeletal system
23.4
15.1
21
9
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.4
15.0
798
5943
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.5
15.0
96
2015
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
3.7
14.9
64
173
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
2.9
14.9
91
318
R3130
NOMESCO Finland
Training in activities of daily lining
56.8
14.8
17
*
9260
FHL
Alloarthroplasty, endoprosthesis or implant
56.8
14.8
17
*
M05BB03
ATC
alendronic acid and colecalciferol; oral
2.4
14.7
125
530
K07.60
ICD-10 Finland
Snapping jaw
1.9
14.7
224
1217
M65.9
ICD-10 Finland
Synovitis and tenosynovitis, unspecified
2.4
14.6
129
556
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.5
14.5
504
3448
NDG63
NOMESCO Finland
Arthroplasty of II-V MCP joint
150.4
14.5
15
*
L16
ICPC
Ankle symptom/complaint
1.5
14.3
448
2993
L08
ICPC
Shoulder symptom/complaint
1.4
14.3
880
6713
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
2.4
14.3
118
491
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.7
14.2
319
1958
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
3.9
14.2
58
151
RJ412
NOMESCO Finland
NA
9.7
14.2
28
29
A46
ICD-10 Finland
Erysipelas
1.5
14.1
571
4031
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
2.7
14.1
93
344
SPAT1325
SPAT
Vaccination
1.3
14.0
1584
13198
S20
ICPC
Corn/callosity
2.7
14.0
97
369
M01AB01
ATC
indometacin; systemic, rectal
1.7
13.9
321
1983
M05BA01
ATC
etidronic acid; systemic
5.0
13.9
44
89
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
13.9
721
5341
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
3.0
13.9
80
270
NCK10
NOMESCO Finland
Partial or total excision of bone of elbow or forearm, other location
17.6
13.8
21
12
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.6
13.8
96
367
RF421
NOMESCO Finland
NA
4.7
13.7
46
99
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
3.0
13.7
79
267
A02BB01
ATC
misoprostol; oral
5.0
13.6
43
87
RK221
NOMESCO Finland
NA
75.3
13.6
15
*
M06.2
ICD-10 Finland
Rheumatoid bursitis
75.3
13.6
15
*
RK224
NOMESCO Finland
NA
75.3
13.6
15
*
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.2
13.5
139
647
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.5
13.5
535
3765
G63.6*M05.3
ICD-10 Finland
Rheumatoid polyneuropathy
140.3
13.4
14
*
D64.9
ICD-10 Finland
Anaemia, unspecified
1.5
13.4
415
2761
L60
ICPC
Musculoskeletal, Result test/procedure
7.4
13.4
31
42
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
3.0
13.3
76
254
M35.3
ICD-10 Finland
Polymyalgia rheumatica
1.9
13.3
188
996
H25.1
ICD-10 Finland
Senile nuclear cataract
1.3
13.3
1057
8389
A10BA02
ATC
metformin; oral
0.7
13.2
767
9836
H16.9
ICD-10 Finland
Keratitis, unspecified
2.7
13.1
87
324
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
13.0
1790
15248
RJ120
NOMESCO Finland
NA
10.9
13.0
24
22
RF222
NOMESCO Finland
NA
28.4
12.9
17
6
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
3.2
12.9
67
212
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
2.0
12.9
170
875
NHQ40
NOMESCO Finland
Amputation of toe
3.0
12.9
72
240
A04AA01
ATC
ondansetron; systemic, rectal
1.6
12.8
313
1964
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.3
12.8
1264
10326
NB1AD
NOMESCO Finland
Shoulder CT examination
2.8
12.8
82
299
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.3
12.8
114
495
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.6
12.8
375
2469
K02.1
ICD-10 Finland
Caries of dentine
1.2
12.7
2631
23448
NAG42
NOMESCO Finland
Posterior fusion of cervical spine with or without fixation
9.7
12.7
25
26
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
12.7
1333
10978
NDB20
NOMESCO Finland
Primary total prosthetic replacement of joint of wrist not using cement, all parts
70.0
12.6
14
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
1.7
12.6
259
1550
7143C
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Juvenile chronic polyarthritis[POLYARTHRITIS JUVENILIS SERONEGATIVA]
32.1
12.6
16
5
NCF15
NOMESCO Finland
Synovectomy of elbow joint, arthroscopic
24.3
12.4
17
7
M25.4
ICD-10 Finland
Effusion of joint
3.0
12.4
71
238
R60.0
ICD-10 Finland
Localized oedema
1.5
12.4
486
3413
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.3
12.3
1079
8669
RF110
NOMESCO Finland
NA
8.0
12.3
27
34
XG410
NOMESCO Finland
Flow-volume spirometry
1.9
12.2
187
1023
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
1.6
12.1
294
1848
NHL50
NOMESCO Finland
Tenolysis or tenosynovectomy of foot
4.5
12.0
41
91
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
7.2
12.0
28
39
NDL99
NOMESCO Finland
Other operation on muscle or tendon of wrist or hand
7.5
11.9
27
36
M05BX03
ATC
strontium ranelate; oral
3.7
11.9
50
135
NHL99
NOMESCO Finland
Other operation on muscle or tendon of ankle or foot
4.0
11.8
46
116
J01MA14
ATC
moxifloxacin; systemic
1.5
11.8
383
2583
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
11.8
970
7720
NF1AT
NOMESCO Finland
Puncture of hip joint with ultrasound guidance
4.9
11.7
37
76
SPAT1204
SPAT
Arthrocentesis
3.5
11.5
53
154
RJ126
NOMESCO Finland
NA
11.1
11.5
21
19
SBA10
NOMESCO Finland
Measurement of excretion of saliva
3.0
11.5
64
214
M66.2
ICD-10 Finland
Spontaneous rupture of extensor tendons
8.6
11.5
24
28
R03AC02
ATC
salbutamol; inhalant
1.2
11.5
2494
22247
RT340
NOMESCO Finland
NA
+∞
11.5
11
*
H02BX01
ATC
methylprednisolone, combinations; systemic
1.7
11.4
248
1507
9526
FHL
Autoarthroplasty (eg Vainio)
120.2
11.4
12
*
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
2.8
11.4
71
254
J01FA06
ATC
roxithromycin; oral
1.2
11.4
1946
16924
NHG70
NOMESCO Finland
Arthroplasty of first tarsometatarsal joint
2.3
11.4
99
427
R05
ICD-10 Finland
Cough
1.3
11.3
881
6954
RD211
NOMESCO Finland
NA
1.8
11.3
203
1167
L01BB01
ATC
NA
8.3
11.3
24
29
RT172
NOMESCO Finland
NA
9.6
11.2
22
23
WX002
NOMESCO Finland
Sedation and analgesia
1.3
11.2
898
7116
RF433
NOMESCO Finland
NA
12.7
11.1
19
15
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
3.9
11.1
44
113
M01AE52
ATC
naproxen and esomeprazole; oral
1.9
11.1
164
884
A55
ICPC
General and Unspecified, Local injection/infiltration
3.8
11.1
46
123
R06.0
ICD-10 Finland
Dyspnoea
1.3
11.1
1095
8927
RK120
NOMESCO Finland
NA
5.4
11.0
32
60
SPAT1299
SPAT
Other function in accordance with podiatry nomenclature
2.5
11.0
82
328
A01
ICPC
Pain general/multiple sites
1.5
11.0
326
2154
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
1.8
10.9
193
1104
M35.7
ICD-10 Finland
Hypermobility syndrome
2.8
10.9
66
234
RJ420
NOMESCO Finland
NA
5.3
10.8
32
61
QDA10
NOMESCO Finland
Incision of skin of lower limb
4.1
10.8
40
97
M81.0
ICD-10 Finland
Postmenopausal osteoporosis
2.0
10.8
128
637
WX120
NOMESCO Finland
Intravenous local anesthesy of arm
2.5
10.8
80
319
71200
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Juvenile rheumatoid arthritis
9.6
10.7
21
22
E85.3
ICD-10 Finland
Secondary systemic amyloidosis
28.1
10.7
14
5
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.0
10.7
140
721
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
10.7
753
5855
M05.1
ICD-10 Finland
Rheumatoid lung disease
60.1
10.6
12
*
WX200
NOMESCO Finland
Interscalenous plexus blockade
2.3
10.5
97
433
M79.7
ICD-10 Finland
Fibromyalgia
1.9
10.5
153
821
SPAT1251
SPAT
Organisation of medication
1.9
10.4
157
854
NHL14
NOMESCO Finland
Shortening or lengthening of achilles tendon
3.6
10.4
46
130
I32.8*M05.3
ICD-10 Finland
Pericarditis (in) rheumatoid
+∞
10.4
10
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.2
10.4
1344
11307
KMAK
NOMESCO Finland
NA
1.2
10.3
2402
21488
1008
NOMESCO Finland
NA
12.0
10.3
18
15
TNC10
NOMESCO Finland
Joint puncture, elbow joint
32.6
10.3
13
*
0108
NOMESCO Finland
NA
32.6
10.3
13
*
SPAT1301
SPAT
No procedures
1.2
10.3
1423
12060
NGF10
NOMESCO Finland
Total synovectomy of knee, open
10.6
10.3
19
18
E0000UV
ATC
NA
1.2
10.2
1779
15452
NDB70
NOMESCO Finland
Prosthetic replacement of one IP joint
18.8
10.2
15
8
L88
ICD-10 Finland
Pyoderma gangrenosum
7.4
10.2
23
31
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
0.5
10.1
69
1410
A10AA01
ATC
NA
2.1
10.1
111
536
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
10.0
2363
21150
M01AB05
ATC
diclofenac; systemic, rectal
1.2
10.0
3299
30472
WX110
NOMESCO Finland
Local anesthesy
1.2
9.9
3323
30731
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
2.6
9.9
71
279
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
9.8
118
590
GD1AD
NOMESCO Finland
Thorax CT examination
1.7
9.8
186
1090
M02AA10
ATC
ketoprofen; topical
1.3
9.8
733
5748
J01DA01
ATC
[U] cefalexin; systemic
1.2
9.7
3035
27858
J70.2
ICD-10 Finland
Acute drug-induced interstitial lung disorders
7.4
9.7
22
30
NHG26
NOMESCO Finland
Fusion between bones of ankle or ankle and foot
2.6
9.5
65
248
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
1.7
9.5
175
1017
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.1
9.5
107
521
H04AA01
ATC
glucagon; nasal, parenteral
2.4
9.5
81
347
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
9.1
9.5
19
21
R81
ICPC
Pneumonia
1.9
9.5
139
750
M01AB08
ATC
etodolac; oral
1.5
9.5
336
2309
B01AX06
ATC
[U] rivaroxaban; oral
2.0
9.5
111
550
7230B
ICD-9 Finland
Other disorders of cervical region, Spinal stenosis of cervical region[SUBLUXATIO ATLANTO-AXIALIS]
100.2
9.4
10
*
TNF10
NOMESCO Finland
Puncture of hip joint
7.5
9.4
21
28
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
2.4
9.4
78
332
L15
ICPC
Knee symptom/complaint
1.3
9.4
930
7567
NCC30
NOMESCO Finland
Secondary implantation of prosthesis in elbow joint, two parts
+∞
9.4
9
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
9.4
963
7873
ZZH40
NOMESCO Finland
Substitute of bone
2.9
9.4
54
185
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
9.3
1852
16272
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.2
9.3
1215
10221
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
2.6
9.3
64
247
M70.2
ICD-10 Finland
Olecranon bursitis
1.9
9.2
121
628
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.2
9.2
1547
13356
M15.3
ICD-10 Finland
Secondary multiple arthrosis
4.5
9.2
31
69
NK6PA
NOMESCO Finland
Measurement of bone density from one location with X-ray
5.4
9.2
26
48
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
1.7
9.2
199
1214
J05AB01
ATC
aciclovir; systemic
1.3
9.1
947
7751
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
1.8
9.1
153
866
5BA08
NOMESCO Finland
NA
3.8
9.1
37
99
NH3CG
NOMESCO Finland
Extensive MRI of foot
3.8
9.1
37
99
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
4.6
9.1
30
66
RD210
NOMESCO Finland
NA
2.4
9.0
75
320
S42.2
ICD-10 Finland
Fracture of upper end of humerus
1.7
9.0
194
1185
SPAT1252
SPAT
Overall medication plan or its review
1.5
8.9
287
1931
NBB20
NOMESCO Finland
Primary total prosthetic replacement of humero-scapular joint
2.7
8.9
58
217
N05AF03
ATC
chlorprothixene; systemic
0.3
8.9
17
585
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
0.5
8.8
54
1144
PJA12
NOMESCO Finland
Sentinel node biopsy
0.6
8.8
183
2800
M35.1
ICD-10 Finland
Other overlap syndromes
4.4
8.7
30
69
H02AB02
ATC
dexamethasone; systemic
0.7
8.7
249
3583
NDT99
NOMESCO Finland
Other operation on wrist or hand
14.0
8.7
14
10
A02BC05
ATC
esomeprazole; systemic
1.2
8.7
1929
17098
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
2.2
8.6
82
374
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
8.5
3352
31217
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
1.9
8.5
117
621
N03AX16
ATC
pregabalin; oral
1.2
8.5
1063
8886
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
4.2
8.5
30
71
RJ530
NOMESCO Finland
NA
20.0
8.5
12
6
L29
ICPC
Musculoskeletal sympt/complt other
1.5
8.3
322
2254
9311
FHL
Knee cleansing surgery (synovectomy, debridement)
7.8
8.3
18
23
TEA00
NOMESCO Finland
Biopsy of lip
2.9
8.3
48
165
NBF10
NOMESCO Finland
Humeroscapular synovectomy, open
+∞
8.3
8
*
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
1.7
8.3
162
959
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
0.6
8.3
121
2003
M00.0
ICD-10 Finland
Staphylococcal arthritis and polyarthritis
8.5
8.3
17
20
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
1.8
8.2
132
737
N05AH03
ATC
olanzapine; systemic
0.5
8.2
78
1442
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
1.6
8.2
191
1190
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
0.6
8.2
89
1587
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.5
8.2
307
2139
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.2
8.1
1017
8492
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.3
8.1
797
6469
H16.8
ICD-10 Finland
Other keratitis
6.0
8.1
21
35
TNX99
NOMESCO Finland
Other orthopaedic minor procedure
1.8
8.1
127
703
7143B
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Juvenile chronic polyarthritis[POLYARTHRITIS JUVENILIS SEROPOSITIVA]
33.4
8.1
10
*
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
2.0
8.0
92
455
NB1AT
NOMESCO Finland
Puncture of shoulder with ultrasound guidance
3.1
8.0
41
132
9477
FHL
Cleansing or splitting of a tendon or tendon sheath (eg tenosynovectomy, tenolysis)
4.0
8.0
30
75
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
1.9
8.0
117
633
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
2.5
8.0
60
244
J01AA02
ATC
doxycycline; systemic
1.2
8.0
3980
37715
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
8.0
2577
23537
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
2.0
8.0
102
525
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
2.0
7.9
95
476
B01AF01
ATC
rivaroxaban; oral
1.3
7.9
485
3684
M02.8
ICD-10 Finland
Other reactive arthropathies
4.7
7.9
25
53
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
7.9
1663
14640
R4180
SPAT
NA
4.5
7.8
26
58
RF220
NOMESCO Finland
NA
2.3
7.8
68
298
N05BA04
ATC
oxazepam; oral
0.8
7.8
766
9271
A03
ICPC
Fever
1.3
7.8
590
4628
ZZH32
NOMESCO Finland
Bone allograft, block
10.8
7.8
14
13
-50
ICPC
Medication/prescr/renewal
1.6
7.8
177
1099
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
0.3
7.8
20
594
M43.3
ICD-10 Finland
Recurrent atlantoaxial subluxation with myelopathy
45.0
7.7
9
*
A02BC01
ATC
omeprazole; systemic
1.2
7.7
1234
10576
ND1DA
NOMESCO Finland
Bilateral wrist X-ray examination
15.0
7.7
12
8
K08.3
ICD-10 Finland
Retained dental root
1.5
7.7
265
1813
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
2.0
7.7
87
429
9273
FHL
Other surgery for toe deformity or pain condition, e.g., Morton, hammer toe
2.7
7.6
49
182
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
2.9
7.6
44
153
7165A
ICD-9 Finland
Other and unspecified arthropathies, Unspecified polyarthropathy or polyarthritis
18.4
7.6
11
6
G63.6
ICD-10 Finland
Polyneuropathy in other musculoskeletal disorders
25.0
7.6
10
*
M75.5
ICD-10 Finland
Bursitis of shoulder
1.9
7.5
99
517
-44
ICPC
Preventive immunization/medic
1.4
7.5
339
2445
NDG79
NOMESCO Finland
Other excision, reconstruction or fusion of joint of II-V finger
8.8
7.5
15
17
R5110
SPAT
NA
1.9
7.5
109
591
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.2
7.5
936
7811
XA402
NOMESCO Finland
ENMG
1.8
7.5
112
612
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.5
7.5
210
1374
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.4
7.4
299
2111
SPAT1260
SPAT
Consultation of another employee
1.3
7.4
772
6311
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
3.1
7.4
37
118
T89
ICPC
Diabetes insulin dependent
1.7
7.4
136
796
M11.2
ICD-10 Finland
Other chondrocalcinosis
4.5
7.4
24
53
A10AA02
ATC
NA
1.8
7.3
121
684
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.2
7.3
1825
16274
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
1.8
7.3
119
670
TQW11
NOMESCO Finland
Vacuum treatment of wound
2.1
7.3
77
368
B01AB04
ATC
dalteparin; parenteral
1.6
7.3
199
1291
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
2.4
7.3
59
251
M45
ICD-10 Finland
Ankylosing spondylitis
2.1
7.3
80
391
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
1.6
7.3
177
1118
1XC0Y
NOMESCO Finland
NA
+∞
7.3
7
*
M14
ICD-10 Finland
Arthropathies in other diseases classified elsewhere
+∞
7.3
7
*
HAB40
NOMESCO Finland
Wedge excision of mammary gland
0.6
7.3
107
1767
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.1
7.3
75
357
NFC40
NOMESCO Finland
Repair of hip prosthesis by bone transplant to acetabulum
4.1
7.3
26
63
WX213
NOMESCO Finland
Lower leg blockade
3.3
7.2
34
104
NE1BA
NOMESCO Finland
Pelvis extensive X-ray examination
2.4
7.2
60
256
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
0.6
7.2
154
2341
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.2
7.2
1477
12950
WX290
NOMESCO Finland
Other blockade of nerve
1.2
7.1
1852
16570
4AB0X
NOMESCO Finland
NA
20.0
7.1
10
5
NH1DA
NOMESCO Finland
Bilateral ankle X-ray examination
20.0
7.1
10
5
TNH11
SPAT
NA
20.0
7.1
10
5
SPAT1216
SPAT
Assessment of functional ability
1.3
7.1
627
5019
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
2.0
7.1
83
417
N05AH02
ATC
clozapine; systemic
0.2
7.1
6
327
K11.7
ICD-10 Finland
Disturbances of salivary secretion
7.9
7.1
15
19
Z22.30
ICD-10 Finland
Latent tuberculosis
12.0
7.1
12
10
N05AH04
ATC
quetiapine; oral
0.8
7.1
387
5028
J01FA10
ATC
azithromycin; systemic
1.2
7.1
2715
25056
RS211
NOMESCO Finland
NA
4.5
7.1
23
51
GX1K5
NOMESCO Finland
Diffusion capacity
5.6
7.0
19
34
WX214
NOMESCO Finland
Plexus blockade at the ankle
3.7
7.0
28
75
N08.4*E85.9
ICD-10 Finland
Glomerular disorders in amyloidosis
10.0
7.0
13
13
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.4
7.0
323
2344
N04AA02
ATC
biperiden; systemic
0.3
7.0
11
416
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.3
7.0
557
4404
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
6.9
2620
24138
NDL32
NOMESCO Finland
Suture or reinsertion of tendon of wrist or hand, extensor tendon
2.6
6.9
46
177
RJ516
NOMESCO Finland
NA
13.8
6.9
11
8
J45.9
ICD-10 Finland
Asthma, unspecified
1.3
6.9
735
6024
ZZH22
NOMESCO Finland
Graft of patients own bone, block
3.5
6.9
30
87
A07AA02
ATC
nystatin; oral
1.5
6.8
257
1796
S01AD03
ATC
aciclovir; ophthalmic
1.6
6.8
146
895
N05AA02
ATC
levomepromazine; systemic
0.5
6.8
50
993
C03CA01
ATC
furosemide; systemic
1.2
6.8
1118
9597
7102B
ICD-9 Finland
Diffuse diseases of connective tissue, Sicca syndrome[SYNDROMA SICCUM SECUNDARIUM]
10.9
6.8
12
11
K07
ICPC
Swollen ankles/oedema
1.6
6.8
165
1042
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
6.8
2180
19818
N05AX08
ATC
risperidone; systemic
0.6
6.8
124
1945
TNA11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, back or neck
16.7
6.7
10
6
I00
ICD-10 Finland
Rheumatic fever without mention of heart involvement
16.7
6.7
10
6
RF431
NOMESCO Finland
NA
16.7
6.7
10
6
QDH00
NOMESCO Finland
Avulsion of toe nail
4.7
6.7
21
45
TND11
SPAT
NA
7.2
6.7
15
21
RK260
NOMESCO Finland
NA
7.2
6.7
15
21
M08.2
ICD-10 Finland
Juvenile arthritis with systemic onset
22.5
6.7
9
*
ZX114
NOMESCO Finland
Intramuscular
2.1
6.6
68
324
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.4
6.6
262
1849
J94.8
ICD-10 Finland
Other specified pleural conditions
2.2
6.6
62
282
NGC30
NOMESCO Finland
Secondary implantation of prosthesis in knee joint, special prosthesis
3.0
6.6
35
117
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.5
6.6
246
1711
N05AD01
ATC
haloperidol; systemic
0.4
6.6
24
614
TEG00
NOMESCO Finland
Punction of mandibular joint
6.4
6.6
16
25
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
2.1
6.6
69
329
B99
ICD-10 Finland
Other and unspecified infectious diseases
2.0
6.6
74
365
R11
ICD-10 Finland
Nausea and vomiting
1.4
6.6
304
2206
C07AA05
ATC
propranolol; systemic
0.8
6.6
558
6869
EBA00
NOMESCO Finland
Extraction of tooth
1.2
6.6
1365
11963
L55
ICPC
Musculoskeletal, Local injection/infiltration
12.2
6.6
11
9
J01MA02
ATC
ciprofloxacin; systemic
1.2
6.6
1686
15043
S22.3
ICD-10 Finland
Fracture of rib
1.5
6.6
234
1618
R05
ICPC
Cough
1.2
6.6
952
8066
RF310
NOMESCO Finland
NA
3.9
6.5
25
65
A98
ICPC
Health maint/preventive medicine
1.3
6.5
5152
50372
E11
ICD-10 Finland
Type 2 diabetes mellitus
0.8
6.5
388
4985
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
0.5
6.5
66
1194
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.3
6.5
436
3365
8070/3-C34.1
ICD-O-3
Squamous cell carcinoma, NOS, of upper lobe, lung
3.9
6.5
24
61
I30.9
ICD-10 Finland
Acute pericarditis, unspecified
3.6
6.5
27
76
4AA12
NOMESCO Finland
NA
5.3
6.4
18
34
RF214
NOMESCO Finland
NA
5.7
6.4
17
30
M86.1
ICD-10 Finland
Other acute osteomyelitis
5.7
6.4
17
30
N07BB01
ATC
disulfiram; oral
0.5
6.4
48
949
ZZH30
NOMESCO Finland
Bone allograft
14.3
6.4
10
7
K57.2
ICD-10 Finland
Diverticular disease of large intestine with perforation and abscess
1.9
6.4
85
447
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
2.5
6.3
45
178
K05.31
ICD-10 Finland
Periodontitis pronounced
1.3
6.3
394
3006
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
1.6
6.3
146
913
RJ414
NOMESCO Finland
NA
5.5
6.3
17
31
L03.9
ICD-10 Finland
Cellulitis, unspecified
2.0
6.3
76
386
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
2.1
6.3
67
324
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
1.7
6.3
129
783
RJ425
NOMESCO Finland
NA
9.2
6.3
12
13
NHF10
NOMESCO Finland
Synovectomy of ankle, open
18.0
6.3
9
5
9508
FHL
Tendon or muscle transposition
18.0
6.3
9
5
M81.4
ICD-10 Finland
Drug-induced osteoporosis
3.7
6.3
25
68
ZZH20
NOMESCO Finland
Graft of patients own bone
3.7
6.3
25
68
NBB15
NOMESCO Finland
Primary bipolar prosthetic replacement of humero-scapular joint
26.7
6.2
8
*
9252
FHL
Plaster bandage placement or replacement (no fracture) in the operating room
7.0
6.2
14
20
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.2
6.2
1053
9057
A10BH01
ATC
sitagliptin; oral
0.7
6.2
199
2797
T90
ICPC
Diabetes non-insulin dependent
0.8
6.1
670
8031
N06AB10
ATC
escitalopram; oral
0.8
6.1
554
6770
I25.2
ICD-10 Finland
Old myocardial infarction
1.5
6.1
212
1457
WX212
NOMESCO Finland
Femoral plexus blockade
2.0
6.1
73
372
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.5
6.1
219
1518
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
1.8
6.1
97
547
ZZA00
NOMESCO Finland
Split skin graft
1.8
6.1
104
598
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
3.8
6.1
23
60
SPAT1254
SPAT
Administration of medicine
1.3
6.0
557
4486
TQX00
NOMESCO Finland
Needle biopsy of skin
8.6
6.0
12
14
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
2.9
6.0
33
114
NH1DG
NOMESCO Finland
Ankle and foot very extensive MRI examination with high intensity magnet
4.9
6.0
18
37
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
0.5
6.0
51
973

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
3856
22937
2.74
322.83
2.6
2.2
79.0
78.5
nmol/l
0.54
3685
20527
381
409
9.85
322.23
1.7
1.3
22526.0
131588.9
e6/l
2.20
286
272
2529
12400
2.73
309.00
6.1
3.6
—
—
—
0
0
3129
8836
6.02
307.65
1.5
1.2
110.0
2.8
u/ml
153.22
1625
3357
5768
27160
13.60
307.65
15.3
5.5
0.2
0.2
e9/l
1.86
5538
23663
4547
26367
3.57
307.65
6.1
3.7
0.0
0.0
estimate
1.57
1124
4694
719
806
9.94
307.65
1.7
1.5
—
—
—
0
0
5842
30638
12.70
307.65
18.4
8.6
4.0
4.1
e9/l
2.95
5575
26590
1568
4147
4.70
307.65
6.1
3.9
0.1
0.2
%
1.35
321
1169
1515
3967
4.71
307.65
5.3
3.8
0.3
0.6
%
6.41
257
914
5753
26230
14.03
307.65
14.9
5.3
0.0
0.0
e9/l
16.12
5477
22428
1406
3815
4.45
307.65
3.9
2.7
10.0
10.6
g/l
6.51
1358
3467
5245
25270
7.26
307.65
15.7
5.6
27.6
28.1
%
2.64
5158
23400
1734
6641
3.22
307.65
1.3
1.6
—
—
—
0
0
5984
40063
9.96
307.65
12.8
3.8
15.0
12.5
mm/h
33.63
5905
36962
2541
7116
5.29
307.65
1.4
1.3
481.3
554.9
titre
1.20
718
1512
5232
24909
7.33
307.65
15.1
5.4
57.7
57.1
%
3.59
5147
23163
4529
25960
3.61
307.65
6.0
3.6
0.0
0.0
estimate
0.88
1102
4717
566
706
8.71
307.65
1.6
1.4
—
—
—
0
0
423
394
11.43
307.65
1.8
1.4
35.2
28.9
%
1.99
279
229
5236
24505
7.56
307.65
15.4
5.5
2.8
2.8
%
0.23
5152
22703
3032
9398
5.27
307.65
1.5
1.3
112.6
20.3
iu/ml
111.01
2226
2733
4145
23370
3.24
307.65
17.8
9.0
0.0
0.0
e9/l
2.05
3785
18950
4298
17707
5.44
307.65
12.9
5.4
—
—
—
0
0
544
534
11.05
307.65
1.8
1.5
53.9
59.4
%
1.71
360
319
520
475
11.84
307.65
1.3
1.5
20.2
23.6
iu/ml
—
9
28
3593
20154
2.81
307.65
5.5
3.4
—
5.7
—
0
14
958
1070
10.37
307.65
1.9
1.5
10741.9
13002.4
e6/l
0.68
764
743
1022
1187
10.07
307.65
1.7
1.3
—
—
—
0
0
5189
23753
7.56
307.65
15.5
5.5
0.8
0.7
%
47.29
5105
22027
1527
3892
4.85
307.65
6.1
3.9
0.0
0.4
%
1.65
285
981
4530
26088
3.59
307.65
7.7
4.9
0.0
0.0
estimate
0.80
1133
4764
5746
26851
13.30
307.65
15.0
5.3
1.8
1.9
e9/l
11.88
5516
23446
5735
26111
13.67
307.65
14.8
5.3
0.6
0.6
e9/l
8.12
5452
22333
5512
36834
4.83
307.65
8.5
4.3
—
—
—
0
0
1588
5254
3.70
307.65
1.3
1.6
—
—
—
0
0
1611
4363
4.61
307.65
6.0
3.9
0.7
0.9
%
2.20
340
1263
5886
41674
6.84
307.65
12.7
7.4
72.8
78.3
u/l
34.45
5820
39111
1316
3349
4.70
307.65
1.2
1.4
—
—
—
0
0
2872
11433
3.77
307.65
8.9
4.2
—
—
—
0
0
5240
24642
7.53
307.65
16.0
5.7
9.2
8.5
%
55.12
5158
22961
207
102
20.95
273.51
1.4
2.1
8.2
9.9
mg/l
1.82
154
84
185
71
26.81
269.42
1.3
1.8
74.5
145.0
au/ml
—
23
10
2590
13533
2.55
269.42
12.2
6.4
—
—
—
0
0
968
3033
3.59
255.62
1.8
1.9
1.2
1.4
g/l
2.56
907
2749
504
994
5.42
243.48
4.1
3.6
57.1
57.7
%
0.46
504
994
3126
18582
2.35
234.97
4.4
3.6
55.8
105.7
e6/l
4.83
2067
13009
746
2098
3.90
230.01
1.2
1.3
0.3
1.3
u/ml
3.28
79
204
231
202
11.83
224.68
1.6
1.5
4.0
5.0
%
0.28
59
39
2500
14003
2.30
209.91
7.6
4.1
0.0
0.0
estimate
1.70
1138
4641
2427
13773
2.24
193.82
2.3
2.5
1753.8
4712.3
umol/l
6.20
2191
11820
934
3693
2.79
161.52
4.8
2.8
3.9
4.1
e9/l
1.19
723
2861
3039
20082
1.99
150.72
7.0
3.9
—
—
—
0
0
381
920
4.34
143.02
1.1
1.2
—
—
—
0
0
6077
53427
4.40
136.22
26.8
13.7
17.2
23.3
mg/l
65.37
5687
42139
84
23
37.00
135.34
1.6
1.7
1.3
1.5
mg/l
0.38
69
14
1477
7773
2.17
133.81
1.5
1.7
—
—
—
0
0
179
227
8.09
131.99
2.8
1.5
—
—
—
0
0
1382
7247
2.16
125.36
2.3
2.0
—
—
—
0
0
136
132
10.51
123.03
1.7
1.2
47.7
58.7
%
2.00
126
109
1834
10985
1.94
113.59
2.8
2.6
5.1
6.2
e6/l
1.66
1656
9578
444
1397
3.34
113.23
1.2
1.3
5.6
7.4
u/ml
0.31
75
239
438
1381
3.33
111.29
1.2
1.3
7.9
4.8
u/ml
0.31
57
151
3652
27197
1.81
111.13
6.3
6.6
1.2
1.2
mmol/l
2.28
3130
22854
461
1525
3.18
108.18
1.2
1.3
54.2
38.9
u/ml
0.43
35
96
2433
16204
1.81
106.34
3.4
4.0
7.4
7.4
ph
1.15
481
3083
2158
13947
1.83
103.47
5.3
3.3
—
—
—
0
0
369
1134
3.39
97.48
1.2
1.2
11.1
16.3
u/ml
—
6
18
3319
24627
1.73
96.44
5.6
5.8
1.2
1.2
mmol/l
2.17
3128
22203
2344
15825
1.76
95.04
3.5
3.2
56.0
68.7
e6/l
0.27
1927
12008
2197
14585
1.78
94.24
3.5
3.1
0.4
0.4
e6/l
0.71
1775
10866
1804
11345
1.83
92.51
8.2
4.1
1.0
1.0
kg/l
1.75
221
1716
2132
14170
1.76
90.17
3.3
3.0
—
—
—
0
0
2017
13234
1.77
88.96
2.5
2.2
3.4
2.9
mg/l
11.15
1814
11285
577
2418
2.53
86.24
2.3
1.9
—
—
—
0
0
431
1561
2.89
85.86
1.6
1.6
0.2
0.2
g/l
5.30
408
1469
872
4390
2.14
84.87
6.9
3.4
—
—
—
0
0
5148
44063
1.90
83.95
30.1
16.8
14.2
13.7
%
101.83
5113
43101
435
1622
2.81
82.01
1.6
1.6
1.1
1.2
g/l
2.29
414
1527
184
390
4.83
80.97
1.2
1.1
—
—
—
0
0
1456
8954
1.81
78.30
2.8
2.7
1.0
1.2
e6/l
1.53
977
5017
2035
13878
1.69
75.32
4.6
4.2
—
—
—
0
0
831
4362
2.04
71.58
1.8
2.6
66.6
66.5
g/l
0.17
771
3964
1596
10307
1.73
71.53
1.6
1.5
2.8
2.4
g/l
9.87
1126
6125
722
3624
2.12
70.05
1.7
2.4
—
—
—
0
0
282
902
3.23
69.59
1.7
1.6
—
—
—
0
0
1001
5671
1.91
68.94
2.7
2.4
1.8
1.8
%
0.57
902
5013
325
1140
2.95
68.40
1.2
1.3
72.0
40.3
u/ml
2.29
49
132
495
2206
2.35
64.05
1.3
1.6
8.4
14.5
u/ml
—
7
55
89
122
7.38
61.34
1.5
1.3
39.8
34.1
%
0.61
62
80
221
677
3.35
58.47
1.2
1.3
47.5
52.5
u/ml
0.10
17
52
1278
8198
1.70
56.86
2.2
2.5
11.5
13.0
umol/l
11.03
1202
7594
91
142
6.49
55.67
1.8
1.7
—
—
—
0
0
6079
56983
2.67
53.81
26.9
10.2
25.0
25.6
u/l
2.71
6040
54887
204
657
3.18
49.73
1.3
1.3
—
—
—
0
0
436
2061
2.20
48.71
1.7
2.3
7.8
7.4
g/l
3.29
329
1552
435
2056
2.20
48.62
1.7
2.3
4.1
3.8
g/l
5.12
323
1476
423
2001
2.19
47.15
2.0
2.0
1.2
1.9
ug/l
1.14
376
1772
412
1933
2.21
46.86
1.7
2.3
3.3
3.1
g/l
5.07
325
1512
233
849
2.81
45.64
2.8
3.3
1.2
1.4
%
0.35
186
655
44
35
12.65
45.17
2.3
1.3
—
—
—
0
0
733
4274
1.81
44.73
2.0
2.6
71.9
69.8
e9/l
0.83
552
3216
398
1922
2.14
42.03
1.6
2.3
10.9
10.2
g/l
2.26
343
1617
78
143
5.51
40.54
1.3
1.1
40.6
39.4
g/l
0.24
49
72
945
6105
1.64
39.44
2.0
1.7
—
—
—
0
0
1060
7054
1.60
39.19
2.3
2.5
19.9
22.5
%
8.72
912
6009
1680
12450
1.48
37.60
1.6
1.5
22.0
20.9
nmol/l
0.89
1457
10587
1115
7577
1.57
37.54
2.2
2.5
2.3
2.3
g/l
4.88
1053
7010
37
30
12.40
37.51
2.6
1.4
0.3
1.0
%
0.60
29
19
339
1613
2.16
37.13
1.6
2.2
36.8
37.8
g/l
2.56
300
1385
436
2285
1.98
36.78
1.4
1.7
1.6
1.6
g/l
0.66
371
1955
4102
35762
1.42
36.34
5.4
4.5
843.8
1547.4
e6/l
0.88
63
468
352
1721
2.11
35.93
1.0
1.1
—
—
—
0
0
2847
23391
1.39
35.37
4.2
4.7
34.4
35.5
g/l
21.34
2641
21667
300
1395
2.21
34.79
1.5
1.4
14.7
15.0
iu/ml
0.01
11
37
199
822
2.47
30.33
1.3
1.4
—
—
—
0
0
2768
23048
1.36
29.77
2.9
2.8
135.5
122.6
ug/l
1.55
2601
21289
264
1242
2.17
29.74
2.9
2.2
—
—
—
0
0
144
517
2.83
29.08
2.7
3.3
57.7
57.0
%
0.14
92
333
60
118
5.12
28.92
1.7
2.6
245.8
111.5
au/ml
0.89
14
18
150
553
2.75
28.81
1.3
1.4
—
—
—
0
0
150
553
2.75
28.81
1.3
1.4
—
—
—
0
0
150
553
2.75
28.81
1.3
1.4
—
—
—
0
0
150
553
2.75
28.81
1.3
1.4
—
—
—
0
0
169
662
2.60
28.80
2.4
2.4
—
—
—
0
0
62
127
4.92
28.53
1.7
3.1
6.2
7.4
mg/l
0.54
40
103
233
1071
2.22
27.81
1.3
1.7
—
—
—
0
0
1362
10220
1.42
27.05
3.0
2.8
522.3
532.6
mosm/kgh2o
1.08
1184
8667
147
564
2.64
26.15
2.9
3.9
—
—
—
0
0
732
4949
1.54
24.40
1.8
2.2
346.7
374.0
nmol/l
3.08
685
4533
312
1683
1.90
24.08
2.1
3.3
48.4
89.1
mg/l
0.62
265
1356
311
1683
1.89
23.76
2.1
3.3
36.0
52.6
mg/l
1.14
264
1358
303
1628
1.90
23.67
2.1
3.3
3.6
2.0
ratio
0.30
32
138
555
3554
1.62
23.36
4.3
3.0
—
—
—
0
0
162
705
2.33
22.07
3.0
2.7
—
—
—
0
0
1299
9972
1.38
21.95
1.8
1.8
1161.2
1172.8
nmol/l
0.19
1052
7542
664
4539
1.52
20.89
5.0
4.0
—
—
—
0
0
1104
8316
1.40
20.78
3.2
2.8
2.6
3.0
e6/l
0.56
630
4406
875
6356
1.44
20.19
1.5
1.4
—
—
—
0
0
174
827
2.14
19.19
1.5
1.6
0.8
0.7
g/l
0.28
135
617
2042
17053
1.29
18.76
3.6
3.1
—
—
—
0
0
236
1265
1.90
18.61
2.1
3.4
—
—
—
0
0
6099
59163
1.84
18.53
39.5
20.5
265.1
254.0
e9/l
33.55
6034
57651
6099
59187
1.82
18.16
39.2
20.4
30.7
30.3
pg
55.80
6070
58349
6099
59187
1.82
18.16
39.2
20.4
93.1
91.1
fl
179.31
6071
58350
553
3744
1.52
18.12
2.3
2.4
29.6
23.9
au/ml
0.44
17
207
6100
59202
1.83
18.12
39.4
20.5
6.9
6.7
e9/l
11.07
6017
57512
6099
59194
1.82
18.05
39.4
20.5
4.3
4.5
e12/l
125.10
6016
57512
1839
15224
1.29
17.88
3.0
2.9
1400.7
1272.9
ng/l
0.71
1637
13043
6099
59207
1.82
17.84
39.6
20.6
131.3
134.2
g/l
59.55
6072
58380
812
5943
1.42
17.83
7.8
7.0
5.0
5.1
kpa
2.57
782
5663
811
5941
1.42
17.72
7.8
7.0
11.8
12.4
kpa
2.74
779
5659
1967
16445
1.28
17.66
2.0
2.1
147.9
208.3
u/l
3.07
1862
15378
509
3412
1.53
17.46
1.2
1.3
48.9
51.4
au/ml
0.12
17
156
116
484
2.42
17.45
2.3
2.4
1.0
1.1
e9/l
0.78
63
292
646
4561
1.46
17.20
3.3
3.7
1.2
1.2
mmol/l
1.41
595
3966
730
5279
1.43
17.10
8.1
7.5
94.9
95.8
%
2.79
707
5078
120
519
2.34
16.68
1.4
1.3
6.9
6.8
g/l
0.17
92
354
503
3408
1.52
16.40
4.7
5.0
—
—
—
0
0
119
518
2.32
16.31
1.4
1.3
2.6
2.9
g/l
0.89
90
355
119
518
2.32
16.31
1.4
1.3
0.4
0.4
g/l
0.37
91
354
800
5929
1.40
16.27
7.9
7.1
1.3
1.1
mmol/l
0.69
648
4651
2578
22437
1.25
16.11
2.0
2.0
92.9
96.9
pmol/l
4.10
1450
11239
2199
18828
1.26
15.76
2.6
3.4
2.3
2.4
mmol/l
7.87
1967
16320
118
520
2.29
15.73
1.4
1.3
—
—
—
0
0
98
398
2.49
15.67
1.8
2.3
45.4
41.6
%
0.42
18
51
255
1493
1.74
15.10
1.2
1.2
1818.6
907.6
titre
—
7
55
246
1426
1.75
15.09
1.4
2.0
11.4
11.5
mg/l
0.03
223
1313
117
524
2.26
15.04
1.2
1.2
—
—
—
0
0
1554
18580
0.78
14.98
2.6
2.9
—
—
—
0
0
3155
28282
1.23
14.40
5.2
6.2
9.8
11.0
umol/l
10.39
3013
26795
52
158
3.31
14.18
1.2
1.2
—
—
—
0
0
421
6108
0.67
14.14
1.6
1.7
—
—
—
0
0
2453
21472
1.23
13.87
7.5
8.8
1.2
1.2
inr
1.81
776
6123
1257
10213
1.29
13.52
2.6
3.0
2.5
2.5
mmol/l
0.84
1113
8913
87
372
2.36
12.52
2.0
2.1
15.2
14.9
%
0.05
29
159
88
382
2.32
12.25
2.0
2.1
72.7
72.8
%
0.01
82
363
387
2642
1.50
12.16
2.8
2.7
0.2
0.3
e6/l
3.85
382
2566
653
4914
1.37
11.95
8.8
7.8
117.9
120.8
g/l
3.28
632
4728
79
333
2.39
11.76
1.3
1.3
21.7
11.9
u/l
3.41
73
304
195
1142
1.73
11.62
2.7
2.2
121.4
127.7
g/l
2.79
125
815
71
287
2.49
11.58
1.2
1.5
—
—
—
0
0
389
2691
1.47
11.46
3.6
3.5
—
—
—
0
0
78
332
2.37
11.38
2.6
2.5
508.1
731.3
e6/l
2.55
39
147
78
333
2.36
11.31
2.6
2.5
381.4
541.9
e6/l
2.51
61
282
239
1489
1.63
11.28
1.1
1.2
114.7
149.8
titre
0.33
15
135
5748
55623
1.36
11.13
20.2
13.2
—
—
—
0
0
125
650
1.94
10.95
1.4
1.5
37.4
32.5
g/l
3.27
114
584
100
480
2.10
10.93
1.5
1.5
—
—
—
0
0
178
2954
0.59
10.85
1.4
1.4
—
—
—
0
0
95
449
2.13
10.81
1.3
1.4
5.8
6.4
mmol/l
0.76
79
420
66
270
2.46
10.53
2.9
2.6
47.7
39.3
%
1.85
19
96
74
319
2.34
10.52
2.6
2.5
0.2
0.2
e9/l
0.46
61
279
63
255
2.49
10.29
1.1
1.1
—
—
—
0
0
2814
25461
1.19
10.16
4.2
4.0
—
—
—
0
0
203
1249
1.65
10.11
3.0
3.1
24.7
25.0
mmol/l
0.65
172
1095
272
1796
1.54
10.05
2.6
3.0
0.3
0.3
g/l
0.06
119
681
248
1611
1.56
9.86
3.1
3.2
—
—
—
0
0
380
2696
1.44
9.83
10.2
8.9
24.9
24.3
mmol/l
2.91
353
2523
54
208
2.61
9.78
1.7
2.1
—
—
—
0
0
110
575
1.93
9.55
1.5
1.5
4432.6
1862.3
e6/l
1.01
74
418
3409
31465
1.18
9.46
4.9
4.5
6.6
6.7
mmol/l
0.70
3243
29371
441
3238
1.39
9.38
9.9
8.7
93.1
94.0
%
1.66
436
3227
1411
12046
1.22
9.38
1.7
1.7
1.5
1.2
mg/l
2.81
1144
9202
94
469
2.02
9.33
1.1
1.1
—
—
—
0
0
5721
55535
1.31
9.08
18.7
16.2
3.9
4.0
mmol/l
12.48
5587
54084
5704
55392
1.30
8.68
18.6
16.0
139.3
139.7
mmol/l
25.59
5585
54051
99
518
1.93
8.61
1.5
1.4
41699.3
72336.0
e6/l
0.66
50
300
436
3249
1.37
8.49
7.3
7.0
24.4
24.7
mmol/l
0.74
402
3022
98
515
1.92
8.43
1.5
1.6
—
—
—
0
0
60
266
2.27
8.09
2.2
1.8
2.8
2.5
u/field
0.10
36
189
103
561
1.85
7.96
1.1
1.2
—
—
—
0
0
140
844
1.67
7.64
1.1
1.1
—
—
—
0
0
168
1065
1.59
7.51
2.9
2.8
7.8
8.1
kpa
1.21
154
993
43
170
2.54
7.48
1.2
1.1
—
—
—
0
0
35
125
2.81
7.41
1.2
1.1
—
—
—
0
0
86
456
1.90
7.26
1.5
1.5
—
—
—
0
0
146
905
1.63
7.18
2.9
2.8
—
—
—
0
0
2237
20284
1.16
7.01
3.9
3.5
238.6
46.7
ng/l
0.48
1586
13621
564
4483
1.28
6.99
8.0
6.6
1.3
1.3
mmol/l
0.18
550
4329
66
324
2.05
6.95
1.1
1.1
—
—
—
0
0
54
246
2.21
6.89
2.4
2.4
—
—
—
0
0
327
4381
0.73
6.88
1.3
1.3
—
—
—
0
0
256
1808
1.43
6.88
3.8
3.9
1.4
1.4
mmol/l
0.37
249
1779
38
148
2.58
6.84
1.1
1.4
—
—
—
0
0
48
210
2.30
6.74
1.1
1.1
1360.3
1510.4
miu/ml
0.43
48
210
54
250
2.17
6.63
1.2
1.1
12.8
30.5
u/ml
—
8
24
26
85
3.07
6.45
1.7
1.7
—
—
—
0
0
245
1747
1.42
6.27
1.9
2.2
930.3
646.0
ug/l
0.24
226
1641
409
3162
1.31
6.27
4.1
3.5
5.1
5.2
kpa
2.02
383
2929
524
4201
1.27
6.07
9.0
8.0
—
—
—
0
0
402
3121
1.31
5.99
4.1
3.5
7.4
7.4
ph
0.70
64
398
296
2206
1.36
5.84
1.1
1.1
34.0
1.8
u/ml
—
6
33
167
1123
1.50
5.83
4.2
3.7
—
—
—
0
0
3302
35002
0.88
5.71
2.9
3.1
50.8
47.3
u/l
1.15
3075
32466
766
6451
1.21
5.65
7.7
6.7
103.9
104.4
mmol/l
2.20
744
6318
55
274
2.02
5.64
1.2
1.4
—
—
—
0
0
551
4490
1.25
5.57
2.7
2.8
212.7
178.9
ng/l
1.00
503
4084
1185
10388
1.17
5.56
3.8
3.6
440.9
435.7
ng/l
0.01
956
7990
41
183
2.25
5.56
2.7
2.4
—
—
—
0
0
75
418
1.80
5.51
1.1
1.2
96.1
184.3
titre
1.63
28
82
38
165
2.31
5.49
1.2
1.1
—
—
—
0
0
274
2043
1.36
5.42
5.0
4.6
—
—
—
0
0
73
409
1.79
5.29
2.1
2.1
3.8
2.2
u/field
0.57
32
170
543
4446
1.24
5.26
2.3
2.3
5.8
7.0
ug/l
1.47
486
3872
414
3304
1.27
5.02
1.3
1.3
160.8
189.4
u/ml
0.54
382
3040
213
1545
1.39
5.02
4.0
4.2
3.9
3.9
mmol/l
0.01
197
1458
59
315
1.88
5.00
1.2
1.1
1.1
1.1
ratio
0.65
24
107
89
537
1.67
4.99
1.2
2.0
—
—
—
0
0
32
135
2.38
4.96
1.1
1.1
—
—
—
0
0
32
135
2.38
4.96
1.1
1.1
—
—
—
0
0
32
135
2.38
4.96
1.1
1.1
—
—
—
0
0
24
88
2.73
4.93
1.3
1.2
—
—
—
0
0
104
657
1.59
4.87
7.3
6.3
11.9
11.7
mg/l
0.20
95
614
29
118
2.46
4.86
1.2
1.2
835.5
437.8
ug/l
0.19
12
58
12
28
4.29
4.82
1.1
1.0
—
—
—
0
0
49
250
1.97
4.76
1.3
1.3
—
—
—
0
0
119
780
1.54
4.76
1.3
1.2
4.5
4.4
u/ml
0.03
55
324
49
253
1.94
4.62
2.3
2.1
—
—
—
0
0
554
4617
1.22
4.56
3.4
3.7
5.7
5.8
kpa
1.54
534
4482
800
6903
1.18
4.52
19.6
23.9
1.3
1.3
inr
0.14
135
1023
158
1110
1.43
4.50
3.0
2.5
15.0
16.1
%
3.07
86
554
39
187
2.09
4.50
1.1
1.1
—
—
—
0
0
33
148
2.24
4.49
1.1
1.1
—
—
—
0
0
24
93
2.59
4.46
1.9
2.0
—
—
—
0
0
1303
11684
1.15
4.43
1.6
1.7
23784715.0
32853286.6
pmol/l
0.29
1131
9643
41
202
2.04
4.41
2.1
1.9
50.3
54.9
ug/l
0.32
41
197
202
2712
0.74
4.40
1.7
1.7
—
—
—
0
0
355
2833
1.27
4.35
11.6
9.5
—
—
—
0
0
1901
17484
1.12
4.32
3.3
3.2
33.6
35.1
u/l
0.29
1796
16572
899
7866
1.17
4.27
1.2
1.2
—
—
—
0
0
548
4603
1.21
4.18
3.4
3.7
2.2
2.0
mmol/l
0.73
443
3764
73
1177
0.62
4.17
2.0
3.7
81.5
29.1
u/ml
0.43
68
1146
36
173
2.09
4.15
2.2
2.0
25.9
29.1
%
0.71
31
163
509
4250
1.21
4.13
2.9
3.6
75.2
87.5
ng/l
3.48
446
3624
85
535
1.60
4.10
2.3
2.3
—
—
—
0
0
204
2704
0.75
4.10
2.0
2.2
12.5
12.2
nmol/l
0.20
185
2348
1333
12038
1.14
4.04
1.2
1.3
1.2
1.6
u/ml
0.79
379
3231
73
445
1.65
4.01
1.4
1.8
4.2
4.1
mg/l
0.06
68
427
27
117
2.31
4.00
1.5
1.4
38.5
24.9
%
1.03
22
99
136
952
1.44
4.00
1.4
1.4
69.2
62.0
mmol/l
1.19
108
768
475
3966
1.21
3.87
1.5
1.4
—
—
—
0
0
104
1525
0.68
3.84
1.3
1.3
—
—
—
0
0
5124
52445
0.88
3.83
4.0
4.7
5.8
5.9
mmol/l
10.65
4729
47798
25
537
0.46
3.79
1.0
1.1
—
—
—
0
0
35
173
2.03
3.78
2.4
2.1
5.3
9.5
%
2.49
28
160
16
55
2.91
3.73
1.6
1.1
5.1
7.0
mmol/l
—
10
27
125
876
1.44
3.68
1.1
1.2
311.5
289.1
u/ml
0.33
67
545
364
2979
1.24
3.62
1.3
1.2
—
—
—
0
0
104
1506
0.69
3.62
1.5
1.7
280.3
308.2
mu/l
0.44
93
1357
59
351
1.69
3.59
1.2
1.2
31.4
34.2
mmol/l
0.44
44
303
26
119
2.19
3.43
2.0
2.1
27.1
165.6
e6/l
—
7
62
1496
13731
1.12
3.41
3.8
3.8
90.0
91.7
%
1.87
1453
13388
158
1170
1.36
3.40
4.7
4.1
2.4
2.7
mmol/l
0.63
118
800
122
869
1.41
3.33
1.3
1.6
—
—
—
0
0
50
291
1.72
3.32
2.8
3.2
7.4
7.4
ph
0.62
24
102
121
870
1.40
3.15
1.1
1.1
—
—
—
0
0
17
67
2.54
3.12
1.2
1.1
—
—
—
0
0
4940
48204
1.11
3.10
27.9
14.9
38.7
39.4
%
5.77
3376
34182
628
7158
0.86
3.04
2.9
3.1
0.8
0.8
ug/l
0.12
424
4862
766
6797
1.14
3.02
4.3
5.6
1.0
1.0
mmol/l
0.13
723
6308
23
106
2.17
3.02
1.3
1.2
—
—
—
0
0
9
21
4.29
2.99
1.0
1.0
—
—
—
0
0
57
893
0.64
2.98
1.6
2.9
—
—
—
0
0
12
40
3.00
2.97
1.0
1.1
—
—
—
0
0
288
2355
1.23
2.95
3.2
3.9
24.6
24.3
mmol/l
0.92
254
2115
178
1379
1.30
2.87
4.7
4.0
7.4
7.4
ph
4.08
154
1149
36
624
0.57
2.86
1.1
1.1
0.7
3.2
u/ml
3.31
18
219
134
998
1.35
2.84
3.0
3.2
0.9
0.8
nmol/l
0.56
110
759
266
2166
1.24
2.84
5.9
5.3
1.8
1.6
%
0.91
249
2021
442
3782
1.18
2.82
3.0
3.0
4.5
4.6
kpa
0.62
425
3658
223
1782
1.26
2.82
13.4
9.6
—
—
—
0
0
41
238
1.73
2.80
3.8
2.2
8.1
9.3
mmol/l
1.73
34
184
60
386
1.56
2.76
1.3
1.3
0.6
1.0
u/ml
0.49
37
179
897
8093
1.13
2.73
1.9
2.0
29.5
29.7
s
0.48
868
7845
17
72
2.36
2.72
1.4
1.6
—
—
—
0
0
233
1881
1.25
2.71
2.7
2.6
—
—
—
0
0
324
3859
0.83
2.70
1.1
1.2
—
—
—
0
0
70
469
1.50
2.69
1.2
1.1
302.0
360.4
nmol/l
1.78
61
400
107
1446
0.74
2.58
1.8
1.8
4.7
4.6
iu/l
0.03
38
525
187
2345
0.79
2.58
1.4
1.3
33.7
33.0
iu/l
0.11
162
2030
277
2292
1.22
2.57
2.6
2.6
0.7
0.6
%
1.85
256
2187
12
44
2.73
2.54
1.0
1.0
95.9
5.6
iu/ml
—
7
16
44
701
0.63
2.53
1.1
1.6
—
—
—
0
0
13
50
2.60
2.53
3.8
2.6
1.1
0.6
u/field
0.76
13
50
21
101
2.08
2.52
1.5
1.2
3.3
1.8
mmol/l
1.62
12
63
16
336
0.47
2.40
1.1
1.1
—
—
—
0
0
50
320
1.57
2.40
1.5
1.6
5.2
6.5
u/l
1.10
42
274
498
4367
1.15
2.37
1.1
1.2
—
—
—
0
0
9
29
3.11
2.22
1.0
1.0
—
—
—
0
0
9
29
3.11
2.22
1.0
1.0
—
—
—
0
0
626
5605
1.13
2.19
4.2
4.3
—
—
—
0
0
20
101
1.98
2.15
1.3
1.4
—
—
—
0
0
31
182
1.71
2.10
1.3
1.5
45.7
64.5
%
1.75
24
149
38
236
1.61
2.10
1.1
1.2
—
—
—
0
0
123
954
1.30
2.06
1.3
1.4
—
—
—
0
0
78
565
1.39
2.06
3.1
5.0
7.0
7.4
mmol/l
0.31
64
470
1406
13167
1.09
2.05
2.4
2.3
—
—
—
0
0
16
76
2.11
2.02
1.7
1.7
—
—
—
0
0
345
2985
1.16
2.01
2.5
2.4
—
—
—
0
0
293
2503
1.18
2.00
1.2
1.2
—
—
—
0
0
76
552
1.38
1.99
4.1
3.2
—
—
—
0
0
719
6534
1.11
1.97
1.9
2.2
148.4
132.2
ug/g
0.65
576
5084
76
1031
0.73
1.96
1.3
2.0
—
—
—
0
0
255
2158
1.19
1.95
6.0
5.4
0.9
0.9
%
0.64
239
2015
1805
17108
1.08
1.93
2.4
2.5
62.5
57.5
u/l
1.53
1669
15731
78
1051
0.74
1.93
2.5
2.9
31.5
35.0
umol/l
0.83
68
892
65
900
0.72
1.91
1.2
1.2
—
—
—
0
0
24
136
1.77
1.86
2.1
1.5
—
—
—
0
0
39
590
0.66
1.86
1.5
2.6
—
—
—
0
0
81
602
1.35
1.86
1.2
1.3
—
—
—
0
0
298
3449
0.86
1.86
2.9
3.8
64.3
57.0
u/ml
0.15
285
3314
506
4527
1.13
1.83
5.7
7.2
9.6
9.7
mmol/l
0.13
481
4316
53
752
0.70
1.82
1.4
1.4
—
—
—
0
0
55
774
0.71
1.80
1.5
1.5
—
—
—
0
0
100
771
1.30
1.80
1.7
1.7
—
—
—
0
0
53
750
0.70
1.79
1.4
1.4
—
—
—
0
0
17
87
1.96
1.79
1.0
1.1
—
—
—
0
0
167
1370
1.22
1.79
1.2
1.2
—
—
—
0
0
40
595
0.67
1.77
3.4
2.6
—
—
—
0
0
680
6201
1.11
1.77
1.2
1.3
—
—
—
0
0
108
844
1.28
1.76
1.2
1.4
138.5
118.6
u/ml
0.26
28
172
149
1210
1.24
1.76
7.6
7.3
11.5
11.2
mmol/l
0.41
136
1077
159
1301
1.23
1.75
1.2
1.2
—
—
—
0
0
149
1211
1.24
1.75
7.6
7.3
104.9
105.2
mmol/l
0.28
136
1078
38
569
0.67
1.74
1.1
1.1
0.6
3.5
u/ml
5.11
17
206
58
803
0.72
1.74
1.2
1.2
—
—
—
0
0
5
13
3.85
1.71
1.0
1.0
—
—
—
0
0
54
381
1.42
1.71
3.1
2.4
—
—
—
0
0
199
1673
1.20
1.68
6.8
6.3
1.5
1.3
mmol/l
1.32
176
1466
25
149
1.68
1.66
1.2
1.5
2.4
3.0
%
0.17
20
127
38
252
1.51
1.65
1.3
1.2
—
—
—
0
0
1161
12355
0.93
1.60
4.3
5.0
2.4
3.6
ug/l
1.95
1046
11051
3899
38070
1.06
1.60
3.8
3.7
—
—
—
0
0
25
151
1.66
1.59
1.6
1.8
88.3
42.5
u/l
0.30
20
141
26
412
0.63
1.58
1.1
1.5
0.8
0.9
g/l
0.94
26
412
10
44
2.27
1.53
1.4
1.2
—
—
—
0
0
24
146
1.65
1.50
2.2
2.3
—
—
—
0
0
15
79
1.90
1.49
1.3
1.5
13.9
10.7
%
—
9
42
78
1006
0.77
1.48
2.3
1.9
1.0
0.8
nmol/l
1.55
68
845
40
276
1.45
1.46
1.1
1.5
—
—
—
0
0
4567
44864
1.06
1.46
35.0
17.9
329.5
331.8
g/l
55.42
4542
44558
18
102
1.77
1.44
1.4
1.2
—
—
—
0
0
185
1571
1.18
1.44
1.2
1.2
—
—
—
0
0
85
1078
0.79
1.43
1.4
1.4
—
—
—
0
0
35
508
0.69
1.42
1.0
1.1
0.1
0.3
u/ml
1.41
11
108
261
2280
1.15
1.42
4.6
3.5
—
—
—
0
0
323
3633
0.88
1.40
2.5
3.3
4.2
4.4
pmol/l
3.13
284
3219
15
81
1.85
1.39
1.6
1.3
0.4
1.7
mmol/l
—
9
53
204
1753
1.17
1.38
1.5
1.7
—
—
—
0
0
14
74
1.89
1.38
1.4
1.3
27.4
477.5
u/l
—
8
54
53
712
0.74
1.37
1.1
1.1
0.1
2.0
u/ml
4.13
17
158
548
5016
1.10
1.37
1.5
1.5
—
—
—
0
0
56
416
1.35
1.37
1.2
1.3
14.8
12.0
mmol/l
0.76
15
101
14
249
0.56
1.36
1.1
1.4
—
—
—
0
0
18
104
1.73
1.36
1.3
1.5
121.4
115.3
ng/l
0.06
18
104
168
1424
1.18
1.35
1.3
1.3
187.0
222.6
miu/ml
0.63
61
681
46
333
1.38
1.32
2.1
2.1
2.4
2.4
ug/l
0.04
39
283
552
6006
0.91
1.31
3.2
4.0
24.2
25.5
ug/l
0.05
452
4815
47
342
1.38
1.31
1.9
2.0
4.4
3.0
ug/l
1.15
41
301
127
1054
1.21
1.29
2.0
2.8
—
—
—
0
0
273
2411
1.14
1.29
3.7
3.3
25.4
25.3
mmol/l
0.25
265
2337
342
3064
1.12
1.29
3.3
3.2
123.4
128.6
g/l
4.40
334
2981
8
34
2.35
1.29
1.1
1.0
—
—
—
0
0
5
18
2.78
1.28
1.0
1.0
—
—
—
0
0
111
1340
0.83
1.22
1.4
2.0
—
—
—
0
0
36
254
1.42
1.21
1.2
1.7
—
—
—
0
0
1803
17333
1.06
1.20
2.5
2.3
—
—
—
0
0
24
156
1.54
1.19
1.1
1.1
—
—
—
0
0
329
3652
0.90
1.18
1.5
1.6
—
—
—
0
0
124
1040
1.20
1.16
2.2
2.9
—
—
—
0
0
59
757
0.78
1.14
1.0
1.1
0.6
1.1
u/ml
0.97
23
303
62
790
0.78
1.14
1.0
1.1
3.9
4.6
u/ml
0.16
33
378
111
1328
0.83
1.13
1.4
2.0
—
—
—
0
0
71
889
0.80
1.13
1.1
1.1
0.8
1.2
u/ml
0.28
33
331
32
225
1.42
1.11
1.8
2.1
138.6
142.0
umol/l
0.02
25
125
112
1335
0.84
1.11
1.4
2.0
—
—
—
0
0
176
2022
0.87
1.10
3.0
3.4
380.3
2844.3
u/ml
1.04
147
1722
35
479
0.73
1.08
1.1
1.5
4.0
3.9
ug/l
0.05
29
400
55
704
0.78
1.06
1.0
1.2
—
—
—
0
0
111
1316
0.84
1.05
1.5
1.9
—
—
—
0
0
72
579
1.25
1.04
1.2
1.2
—
—
—
0
0
475
5136
0.92
1.03
1.4
1.4
—
—
—
0
0
103
1225
0.84
1.01
1.4
2.1
—
—
—
0
0
9
49
1.84
0.98
1.2
1.7
—
—
—
0
0
0
30
0.00
0.97
0.0
1.0
—
—
—
0
0
0
30
0.00
0.97
0.0
1.0
—
1.1
—
0
13
148
1701
0.87
0.97
1.4
1.4
287.8
278.2
ug/g
0.28
96
982
15
92
1.63
0.97
1.9
2.2
3.4
4.3
ug/l
—
6
36
16
100
1.60
0.96
1.6
1.3
—
—
—
0
0
94
1119
0.84
0.95
1.3
1.3
14.9
13.0
u/l
0.57
79
919
0
32
0.00
0.95
0.0
8.0
—
—
—
0
0
179
2022
0.88
0.92
1.1
1.1
—
—
—
0
0
5368
53201
1.06
0.92
4.3
4.5
4.7
4.7
mmol/l
7.89
5029
49145
6
28
2.14
0.91
1.5
1.6
—
—
—
0
0
1607
16642
0.95
0.91
3.8
4.0
8.9
8.7
mg/mmol
0.07
1049
10192
59
730
0.81
0.89
1.1
1.1
1.7
3.1
u/ml
1.47
20
314
20
135
1.48
0.89
2.1
1.8
—
—
—
0
0
59
729
0.81
0.88
1.7
1.4
0.3
0.4
nmol/l
1.44
45
548
220
1976
1.12
0.87
5.0
3.7
25.5
24.9
mmol/l
2.60
204
1813
27
369
0.73
0.87
1.0
1.0
358.8
338.5
ng/l
0.16
22
249
8
45
1.78
0.84
2.5
2.4
—
—
—
0
0
10
57
1.76
0.83
1.1
1.1
—
—
—
0
0
190
2120
0.89
0.82
1.5
1.6
—
—
—
0
0
5052
50028
1.05
0.82
4.8
5.0
2.0
2.1
mu/l
0.93
4661
45842
55
445
1.24
0.80
1.3
1.3
1.8
1.5
nmol/l
1.08
49
406
5328
52839
1.05
0.80
4.2
4.4
1.6
1.5
mmol/l
36.07
4985
48513
9
147
0.61
0.78
2.4
2.3
—
—
—
0
0
8
48
1.67
0.78
1.3
1.1
—
—
—
0
0
5463
54219
1.06
0.78
4.7
5.0
2.7
2.8
mmol/l
22.66
5099
49818
60
492
1.22
0.78
2.3
2.5
—
—
—
0
0
25
182
1.38
0.77
1.4
1.3
—
—
—
0
0
19
267
0.71
0.74
1.0
1.3
157.5
135.2
nmol/l
1.49
19
267
131
1480
0.88
0.72
1.4
1.4
286.9
166.9
pmol/l
0.56
126
1447
19
134
1.42
0.71
2.4
1.7
1.4
0.8
mmol/l
0.26
19
126
4310
42590
1.04
0.70
4.1
4.2
15.1
14.8
pmol/l
15.35
3956
38766
36
283
1.27
0.69
1.3
1.4
1.5
1.3
nmol/l
0.43
25
222
5
27
1.85
0.68
1.0
1.0
—
—
—
0
0
4927
49702
0.96
0.67
5.2
5.8
38.3
39.7
mmol/mol
19.86
4628
45865
25
188
1.33
0.66
1.1
1.1
—
—
—
0
0
7
44
1.59
0.65
1.1
1.0
—
—
—
0
0
29
371
0.78
0.64
1.0
1.0
823.0
702.1
ng/l
0.76
22
242
5
29
1.72
0.64
1.6
1.6
—
—
—
0
0
56
470
1.19
0.62
1.2
1.2
—
—
—
0
0
18
130
1.39
0.61
1.3
1.1
—
—
—
0
0
9
138
0.65
0.60
7.7
5.1
—
—
—
0
0
34
421
0.81
0.58
1.0
1.0
298.7
290.2
mg/l
0.21
29
375
134
1486
0.90
0.58
1.0
1.1
3.2
6.5
u/ml
0.72
11
158
10
150
0.67
0.58
1.2
1.1
—
—
—
0
0
1624
16654
0.97
0.58
3.1
3.2
7.0
7.2
mmol/l
0.80
1398
13941
28
220
1.27
0.56
1.9
2.2
46.5
54.6
umol/l
—
8
177
128
1153
1.11
0.56
1.2
1.3
23.6
24.3
e6/l
0.02
96
883
128
1154
1.11
0.55
1.2
1.2
3.8
3.8
mmol/l
0.05
119
1080
134
1479
0.90
0.54
1.7
2.1
7819.2
4998.7
u/l
0.32
53
594
128
1156
1.11
0.54
1.3
1.4
2290.5
1286.4
e6/l
0.24
103
933
20
151
1.33
0.53
1.6
2.3
—
—
—
0
0
79
693
1.14
0.53
1.2
1.3
291.9
338.5
pmol/l
0.42
62
530
27
336
0.80
0.50
1.2
1.1
0.4
11.3
nmol/l
—
5
73
24
302
0.79
0.49
1.2
1.3
—
—
—
0
0
64
557
1.15
0.49
1.2
1.3
—
—
—
0
0
1547
15828
0.97
0.48
3.1
3.2
586.6
406.5
mg/l
0.63
1027
9644
66
753
0.88
0.48
1.5
1.3
—
—
—
0
0
127
1156
1.10
0.48
4.1
3.4
30.7
26.3
mg/l
0.71
86
705
79
890
0.89
0.48
1.4
1.3
—
—
—
0
0
11
154
0.71
0.47
1.0
1.0
—
—
—
0
0
53
457
1.16
0.46
1.1
1.2
—
—
—
0
0
59
676
0.87
0.46
1.3
1.6
—
—
—
0
0
24
191
1.26
0.46
1.4
1.6
—
—
—
0
0
16
210
0.76
0.46
1.1
1.1
72.2
427.8
ng/l
—
5
49
46
536
0.86
0.45
1.7
1.6
—
—
—
0
0
66
581
1.14
0.45
1.6
1.6
—
—
—
0
0
116
1056
1.10
0.45
1.2
1.3
—
—
—
0
0
83
742
1.12
0.44
1.2
1.5
55.9
57.0
mu/l
0.02
74
657
10
69
1.45
0.44
1.7
1.5
151.2
108.0
ug/l
—
10
58
58
507
1.15
0.44
2.0
1.9
7.6
8.0
umol/l
0.07
42
357
18
139
1.30
0.43
1.1
1.1
292.2
309.6
pmol/l
—
10
102
31
372
0.83
0.43
1.1
1.5
1.6
1.2
promille
1.05
25
283
69
777
0.89
0.43
1.4
1.3
34.7
31.2
u/l
0.28
49
631
28
339
0.83
0.42
1.1
1.1
16.2
10.5
iu/ml
0.25
11
91
19
240
0.79
0.42
1.1
1.4
63.8
179.8
pmol/l
—
8
79
5
32
1.56
0.42
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
593.9
—
0
15
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.9
—
—
—
0
0
8
59
1.36
0.41
1.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
5.6
—
387.9
—
0
17
7
101
0.69
0.39
7.3
8.0
—
—
—
0
0
59
523
1.13
0.38
1.4
1.4
—
—
—
0
0
412
4294
0.96
0.38
1.4
1.4
—
—
—
0
0
25
206
1.21
0.37
2.9
5.0
444.8
1026.4
mg/l
0.24
17
151
1473
14446
1.03
0.37
1.4
1.4
—
—
—
0
0
8
115
0.70
0.37
1.6
2.0
—
—
—
0
0
43
374
1.15
0.36
1.2
1.5
1839.3
1874.4
ml
—
8
89
30
353
0.85
0.36
1.5
2.0
15.8
17.4
nmol/l
0.73
23
331
6
42
1.43
0.35
1.0
1.0
—
—
—
0
0
712
7328
0.97
0.35
1.3
1.3
—
—
—
0
0
125
1346
0.93
0.35
4.3
4.3
—
—
—
0
0
131
1218
1.08
0.34
2.3
2.4
81.0
84.4
ug/min
0.05
73
719
16
127
1.26
0.33
1.1
1.3
25.9
64.1
mu/l
—
10
100
6
46
1.30
0.33
1.0
1.4
—
—
—
0
0
17
138
1.23
0.30
1.9
1.5
—
—
—
0
0
12
150
0.80
0.27
1.4
1.7
—
—
—
0
0
49
542
0.90
0.26
3.8
4.9
40.1
85.9
u/ml
1.23
15
147
8
67
1.19
0.26
28.4
10.1
—
—
—
0
0
58
529
1.10
0.26
1.0
1.1
—
—
—
0
0
18
213
0.84
0.25
1.4
2.9
—
—
—
0
0
9
76
1.18
0.24
1.1
1.1
—
—
—
0
0
16
133
1.20
0.24
1.1
1.1
0.1
1.5
u/ml
—
7
62
6
82
0.73
0.24
1.3
1.5
—
—
—
0
0
6
83
0.72
0.24
1.0
1.0
—
—
—
0
0
5118
50994
1.02
0.23
3.9
4.0
1.2
1.3
mmol/l
23.55
4768
46436
7
91
0.77
0.22
1.9
1.4
—
—
—
0
0
18
153
1.18
0.22
1.1
1.1
—
—
—
0
0
19
163
1.17
0.21
1.4
2.1
795.1
19173.6
e6/l
—
8
93
5
42
1.19
0.21
1.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
30
268
1.12
0.20
2.7
2.8
—
—
—
0
0
80
752
1.06
0.19
1.2
1.2
—
—
—
0
0
10
122
0.82
0.19
1.8
2.3
—
—
—
0
0
21
184
1.14
0.19
1.6
2.4
463.3
783.1
e6/l
0.68
13
133
13
154
0.84
0.19
2.3
1.4
—
—
—
0
0
34
374
0.91
0.18
1.1
1.1
40.4
40.1
mg/l
0.02
28
313
33
363
0.91
0.18
1.1
1.1
227.9
263.8
mg/l
0.80
27
317
137
1314
1.04
0.17
1.2
1.3
932.5
522.7
mg/l
0.65
129
1238
11
91
1.21
0.17
3.3
3.1
—
—
—
0
0
11
91
1.21
0.17
1.1
1.1
—
—
—
0
0
18
158
1.14
0.16
1.8
2.0
—
—
—
0
0
26
287
0.91
0.15
1.2
1.2
—
—
—
0
0
126
1311
0.96
0.15
2.4
2.9
1.6
1.5
mg/l
0.62
112
1200
6
77
0.78
0.15
6.0
7.3
—
—
—
0
0
523
5138
1.02
0.15
2.2
2.2
0.2
0.2
g/l
1.25
475
4802
76
721
1.05
0.15
1.1
1.1
—
—
—
0
0
45
419
1.07
0.15
1.0
1.4
—
—
—
0
0
7
90
0.78
0.14
1.3
2.7
—
—
—
0
0
25
274
0.91
0.13
1.8
2.4
2112.4
1888.7
ml
0.40
17
247
371
3781
0.98
0.13
1.2
1.2
124.1
147.9
iu/ml
0.64
151
1419
83
795
1.04
0.12
1.3
1.2
—
—
—
0
0
84
805
1.04
0.12
1.3
1.3
0.7
2.6
nmol/l
0.69
79
770
59
560
1.05
0.12
1.4
1.4
273.2
277.2
mosm/kgh2o
0.82
44
435
74
708
1.05
0.12
1.1
1.1
1.5
1.5
g/l
0.08
65
637
114
1178
0.97
0.11
2.6
3.4
271.4
612.1
u/ml
0.69
99
1071
882
8732
1.01
0.11
3.1
3.2
0.8
0.8
mmol/l
1.54
806
8128
42
445
0.94
0.11
1.2
1.2
—
—
—
0
0
627
6196
1.01
0.11
2.2
2.7
6.4
8.1
umol/l
2.07
535
5364
35
372
0.94
0.10
5.1
6.5
—
—
—
0
0
29
271
1.07
0.09
7.6
3.3
—
—
—
0
0
22
238
0.92
0.09
1.0
1.0
0.3
2.3
u/ml
—
5
38
1589
15977
0.99
0.09
3.8
3.9
—
—
—
0
0
6
55
1.09
0.08
1.2
1.3
—
640.5
—
0
9
31
292
1.06
0.08
1.8
2.2
504.7
492.2
min
0.22
18
215
59
613
0.96
0.08
2.5
2.3
—
—
—
0
0
143
1462
0.98
0.08
1.1
1.1
—
—
—
0
0
37
389
0.95
0.08
2.1
2.1
7.5
6.6
mmol/l
0.74
27
251
14
127
1.10
0.07
1.0
1.5
13.3
12.9
g/l
—
6
99
147
1441
1.02
0.07
1.2
1.2
—
—
—
0
0
9
88
1.02
0.07
1.0
1.0
5.3
8.3
mg/g
—
9
82
9
105
0.86
0.06
1.3
1.6
—
—
—
0
0
74
720
1.03
0.06
1.1
1.1
—
—
—
0
0
75
770
0.97
0.06
1.1
1.1
101.7
13703.3
iu/ml
0.53
18
171
35
335
1.05
0.06
1.1
1.0
—
—
—
0
0
26
274
0.95
0.06
1.0
1.0
0.5
2.7
u/ml
—
10
80
517
5130
1.01
0.06
2.3
2.4
37.2
46.5
u/l
0.46
439
4363
31
296
1.05
0.05
7.2
3.2
—
—
—
0
0
25
238
1.05
0.05
8.1
11.7
—
—
—
0
0
25
262
0.95
0.04
2.8
2.6
—
31.4
—
0
5
20
210
0.95
0.03
1.3
1.5
30.5
29.9
umol/l
0.15
20
203
26
270
0.96
0.03
1.0
1.0
0.4
0.7
u/ml
0.57
11
62
10
92
1.09
0.03
1.0
1.0
—
—
—
0
0
66
649
1.02
0.02
5.7
2.8
13.6
13.2
%
2.21
66
641
15
158
0.95
0.02
1.7
1.4
—
—
—
0
0
40
407
0.98
0.01
2.0
2.0
11.0
11.1
%
0.02
40
407
14
146
0.96
0.00
1.1
1.1
—
—
—
0
0
38
374
1.02
0.00
1.1
1.1
—
—
—
0
0
2306
23053
1.00
0.00
2.1
2.1
—
—
—
0
0
195
1956
1.00
0.00
1.9
1.9
21.2
21.5
s
0.26
170
1701
13
135
0.96
0.00
1.2
2.1
7.1
2.4
ug/l
—
5
72
37
368
1.01
0.00
1.1
1.1
—
—
—
0
0
16
165
0.97
0.00
1.5
2.1
—
—
—
0
0
30
305
0.98
0.00
1.0
1.0
—
—
—
0
0
40
405
0.99
0.00
1.8
2.2
757.0
625.6
ml
0.78
23
268
31
314
0.99
0.00
5.6
3.5
—
—
—
0
0
1474
14735
1.00
0.00
1.6
1.6
1.3
1.4
mmol/l
4.57
1260
12320
73
733
1.00
0.00
1.3
1.3
—
—
—
0
0
7
70
1.00
0.00
1.4
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
5
54
0.93
0.00
1.0
1.2
11.0
9.5
mg/l
—
5
49
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
65.4
—
0
5
0
5
0.00
0.00
0.0
2.0
—
6.4
—
0
5
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
0.00
5.8
12.1
5.8
5.4
mmol/l
—
6
68
0
6
0.00
0.00
0.0
1.2
—
91.3
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.5
—
0
5
0
5
0.00
0.00
0.0
6.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
8
89
0.90
0.00
1.3
1.5
—
—
—
0
0
7
70
1.00
0.00
1.4
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
25.8
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
89
1.01
0.00
4.7
6.7
—
—
—
0
0
7
70
1.00
0.00
1.4
1.2
—
—
—
0
0
9
99
0.91
0.00
3.9
2.9
9655.0
1787.6
u/l
—
9
94
5
51
0.98
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
6
67
0.90
0.00
5.8
3.7
32.7
42.3
umol/l
—
6
56
5
54
0.93
0.00
1.0
1.2
—
—
—
0
0
7
70
1.00
0.00
1.1
3.0
—
31.4
—
0
11
0
5
0.00
0.00
0.0
6.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
1432.9
—
0
7
51
510
1.00
0.00
3.6
2.9
51.5
27.5
mg/l
0.61
46
368
0
9
0.00
0.00
0.0
1.3
—
2858.5
—
0
9
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
118.3
—
0
8

Mortality – FinRegistry

↥

Association

Association between endpoint RHEUMA_SEROPOS_STRICT and mortality.

Females

Parameter HR [95% CI] p-value
RHEUMA_SEROPOS_STRICT 1.267 [1.16, 1.38] < 0.001
Birth year 0.997 [0.99, 1.01] 0.474

During the follow-up period (1.1.1998 — 31.12.2019), 2802 out of 18091 females with RHEUMA_SEROPOS_STRICT died.

Males

Parameter HR [95% CI] p-value
RHEUMA_SEROPOS_STRICT 1.387 [1.26, 1.52] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 2121 out of 8553 males with RHEUMA_SEROPOS_STRICT died.

Mortality risk

Mortality risk for people of age

years, who have RHEUMA_SEROPOS_STRICT.

N-year risk Females Males
1 0.099% 0.247%
5 0.74% 1.452%
10 2.046% 3.767%
15 3.95% 7.307%
20 6.912% 12.196%

Relationships between endpoints

↥

Index endpoint: RHEUMA_SEROPOS_STRICT – Seropositive rheumatoid arthritis, strict definition

GWS hits: 23

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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