Mixed conductive and sensorineural hearing loss

H8_HL_MIX_NAS

sensorineural hearing loss: Hearing loss in which the root cause lies in the inner ear or sensory organ (cochlea and associated structures) or the vestibulocochlear nerve (cranial nerve VIII).

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H90.6, H90.7, H90.8
  • Hospital discharge: ICD-9 3892
  • Cause of death: ICD-10 H90.6, H90.7, H90.8
  • Cause of death: ICD-9 3892

2 out of 7 registries used, show all original rules.

5262

4. Check minimum number of events

None

5262

5. Include endpoints

None

5262

6. Filter based on genotype QC (FinnGen only)

5044

Control definitions (FinnGen only)

Control exclude
H8_OTHEREAR

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 36727 19869 16663
Only index persons 34045 18719 15326
Unadjusted period prevalence (%)
Whole population 0.52 0.57 0.47
Only index persons 0.64 0.69 0.59
Median age at first event (years)
Whole population 62.97 63.35 62.45
Only index persons 62.24 62.65 61.74

-FinnGen-

Key figures

All Female Male
Number of individuals 5044 2688 2356
Unadjusted period prevalence (%) 1.01 0.95 1.08
Median age at first event (years) 62.00 59.93 64.36

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
5262
Matched controls
52620
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
42.3
307.7
509
133
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
66.0
307.7
197
31
DDA00
NOMESCO Finland
Stapedotomy
89.0
307.7
388
47
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
111.7
307.7
335
32
H90.8
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unspecified
446.4
307.7
629
16
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
5988.6
307.7
3038
12
H02
ICPC
Hearing complaint
5.4
307.7
1268
2917
R4135
NOMESCO Finland
Rehabilitation for hearing problems
55.1
307.7
222
42
DFF15
NOMESCO Finland
Speech audiometry
35.0
307.7
909
312
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
45.9
307.7
831
214
Z3229
NOMESCO Finland
Other healthcare associate professional
5.5
307.7
919
1956
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
134.3
307.7
1114
105
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
34.3
307.7
1231
464
H93.1
ICD-10 Finland
Tinnitus
9.2
307.7
460
541
Z97.4
ICD-10 Finland
Presence of external hearing-aid
50.8
307.7
1095
271
DC1AD
NOMESCO Finland
Temporalbone CT
65.9
307.7
436
72
Z01.1
ICD-10 Finland
Examination of ears and hearing
15.8
307.7
2182
2252
DAX08
NOMESCO Finland
Fitting of hearing aid
59.8
307.7
965
197
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
155.5
307.7
2775
375
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
18.5
307.7
281
160
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
14.2
307.7
301
224
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
6074.2
307.7
2006
5
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
22.3
307.7
496
244
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
4.4
307.7
1137
3130
H91.9
ICD-10 Finland
Hearing loss, unspecified
12.8
307.7
573
497
H65.3
ICD-10 Finland
Chronic mucoid otitis media
17.2
307.7
352
218
R5120
NOMESCO Finland
Preparation of an aid
22.6
307.7
623
311
SPAT1043
SPAT
Audiometry
4.9
307.7
816
1899
H80.0
ICD-10 Finland
Otosclerosis involving oval window, nonobliterative
80.9
307.7
505
69
H71
ICD-10 Finland
Cholesteatoma of middle ear
42.5
307.7
423
108
DFF00
NOMESCO Finland
Pure tone audiometry
37.3
307.7
1968
829
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
288.2
307.7
566
22
UDC00
NOMESCO Finland
Ear microscopy
17.1
307.7
1307
999
H80.9
ICD-10 Finland
Otosclerosis, unspecified
103.3
307.7
530
57
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
234.9
307.7
945
49
H65.2
ICD-10 Finland
Chronic serous otitis media
16.7
291.0
246
154
H91.1
ICD-10 Finland
Presbycusis
7.2
290.5
451
674
H66.0
ICD-10 Finland
Acute suppurative otitis media
5.4
280.0
603
1241
H80.1
ICD-10 Finland
Otosclerosis involving oval window, obliterative
104.2
275.4
142
14
R5140
NOMESCO Finland
Monitoring the use of the aid
3.9
272.0
934
2767
38699, ,
ICD-8 Finland
35.3
271.6
171
50
TDA90
NOMESCO Finland
Removal wax from ear
17.0
265.3
222
136
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
46.3
260.4
153
34
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
20.7
254.9
194
97
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
32.3
247.7
160
51
N07CA01
ATC
betahistine; oral
4.6
232.3
598
1423
3870A
ICD-9 Finland
Otosclerosis involving oval window, nonobliterative
35.9
223.6
140
40
DCD10
NOMESCO Finland
Tympanoplasty
71.0
217.6
118
17
DCD00
NOMESCO Finland
Myringoplasty
22.6
215.6
158
72
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
42.3
213.4
128
31
H74.1
ICD-10 Finland
Adhesive middle ear disease
43.0
210.9
126
30
H80.8
ICD-10 Finland
Other otosclerosis
70.2
202.5
110
16
H90.2
ICD-10 Finland
Conductive hearing loss, unspecified
49.8
202.4
117
24
4133
FHL
Stapedectomy sampling
34.3
195.5
124
37
H70.1
ICD-10 Finland
Chronic mastoiditis
48.1
194.0
113
24
ZXC10
NOMESCO Finland
Use of laser
7.4
192.4
287
408
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
18.3
190.4
153
86
H60.9
ICD-10 Finland
Otitis externa, unspecified
3.9
181.1
574
1587
RK520, ,
NOMESCO Finland
34.2
179.7
114
34
H29
ICPC
Ear symptom/complaint other
3.0
152.0
794
2986
38700
ICD-8 Finland
Other disease of ear and mastoid process, Cholesteatoma of ear
30.0
151.4
100
34
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
24.0
148.4
106
45
H66.9
ICD-10 Finland
Otitis media, unspecified
4.1
146.9
430
1118
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.5
145.3
544
1675
H60.3
ICD-10 Finland
Other infective otitis externa
6.7
144.7
233
359
H81.0
ICD-10 Finland
Ménière disease
7.2
140.3
211
302
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
13.0
136.0
131
103
RK320, ,
NOMESCO Finland
12.5
132.9
131
107
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
27.4
130.8
89
33
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
5.4
129.5
265
515
Z97.8
ICD-10 Finland
Presence of other specified devices
35.8
129.2
81
23
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
23.4
127.6
92
40
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
33.8
125.7
80
24
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.3
125.6
1182
5867
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
24.6
122.9
87
36
DFF10
NOMESCO Finland
Measurement of acoustic impedance (tympanometry and reflex testing)
57.4
120.8
68
12
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
26.0
118.3
82
32
H60.8
ICD-10 Finland
Other otitis externa
5.1
117.8
256
524
RK110, ,
NOMESCO Finland
11.1
115.6
123
113
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
11.7
113.8
117
102
DDB00
NOMESCO Finland
Stapedectomy
45.5
106.7
63
14
H61.2
ICD-10 Finland
Impacted cerumen
3.1
105.8
483
1669
RK120, ,
NOMESCO Finland
22.7
104.1
76
34
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
14.0
104.1
96
70
H04
ICPC
Ear discharge
4.3
101.1
271
657
DFX03
NOMESCO Finland
Review, maintenance and user education for hearing aid
41.1
94.2
57
14
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
43.5
93.8
56
13
H13
ICPC
Plugged feeling ear
2.1
93.3
1124
6071
DFE00
NOMESCO Finland
Insertion of cochlear implant
+∞
93.0
89
*
DEB30
NOMESCO Finland
Radical mastoidectomy
44.6
89.2
53
12
SPAT1352
SPAT
Inspection, maintenance and instruction for use of hearing aid
8.7
86.4
110
129
H65.0
ICD-10 Finland
Acute serous otitis media
6.4
85.8
144
231
H92.0
ICD-10 Finland
Otalgia
3.4
84.2
311
942
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
18.1
81.9
66
37
H01
ICPC
Ear pain/earache
2.4
80.0
606
2697
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
8.4
78.7
103
125
H81
ICPC
Excessive ear wax
2.0
78.3
990
5406
RK290, ,
NOMESCO Finland
20.6
77.6
59
29
H80
ICD-10 Finland
Otosclerosis
203.0
77.4
80
*
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
99.0
71.1
78
8
H84
ICPC
Presbyacusis
3.8
68.9
214
577
H90
ICD-10 Finland
Conductive and sensorineural hearing loss
22.9
68.8
50
22
H91
ICD-10 Finland
Other hearing loss
9.3
68.4
82
89
H60
ICD-10 Finland
Otitis externa
3.1
68.0
294
979
H91.8
ICD-10 Finland
Other specified hearing loss
10.0
67.5
77
78
4141
FHL
Myringoplasty (also for reasons other than inflammation)
13.2
67.3
64
49
R42
ICD-10 Finland
Dizziness and giddiness
1.8
67.1
1261
7794
RK420, ,
NOMESCO Finland
666.7
67.1
66
*
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
5.8
66.9
123
216
DFF16
NOMESCO Finland
Speech-in-noise audiometry
+∞
65.8
63
*
4145
FHL
Tympanomastoidectomy, includes possible tympanoplasty
31.0
65.6
43
14
S02CA02
ATC
flumetasone and antiinfectives; otic
2.7
65.3
365
1400
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
64.9
2543
19126
DFX00
NOMESCO Finland
Connecting cochlear implant
+∞
64.7
62
*
H66
ICD-10 Finland
Suppurative and unspecified otitis media
4.6
64.6
155
344
R01AD09
ATC
mometasone; nasal
1.6
62.3
2111
15262
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
28.2
62.2
42
15
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
5.8
61.4
112
195
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic
3.9
59.3
181
482
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
+∞
57.4
55
*
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.7
57.0
1315
8560
DFF59
NOMESCO Finland
Other assessment of balance
7.3
55.4
81
112
R01AD08
ATC
fluticasone; nasal
1.7
54.8
1335
8806
SPAT1041
SPAT
Comprehensive hearing test
7.6
54.2
77
103
DEA10
NOMESCO Finland
Attico-antrotomy
86.8
54.0
60
7
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
141.5
52.9
56
*
DGW00
NOMESCO Finland
Dilatation of eustachian tube
21.8
52.5
39
18
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
11.9
52.3
53
45
RK220, ,
NOMESCO Finland
10.9
52.1
56
52
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
6.5
51.5
84
131
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
8.6
51.2
65
76
H28
ICPC
Limited function/disability (H)
6.4
51.2
85
135
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
13.5
50.2
47
35
DCA30
NOMESCO Finland
Exploration of middle ear
107.1
48.8
53
5
J01CA04
ATC
amoxicillin; systemic
1.6
48.7
3985
34541
RK530, ,
NOMESCO Finland
472.1
47.4
47
*
G47.3
ICD-10 Finland
Sleep apnoea
1.7
45.4
1071
6954
DDD05
NOMESCO Finland
Plastic repair of ossicular chain
158.1
44.9
47
*
H72
ICD-10 Finland
Perforation of tympanic membrane
15.9
44.3
38
24
38199
ICD-8 Finland
Otitis media without mention of mastoiditis, Unspecified
13.8
44.2
41
30
H81.3
ICD-10 Finland
Other peripheral vertigo
3.2
44.1
174
548
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
12.8
43.4
42
33
N02BE01
ATC
paracetamol; systemic, rectal
1.8
42.8
4518
40841
4150
FHL
Tympanoplasty (including for reasons other than inflammation)
56.1
42.4
50
9
H60.4
ICD-10 Finland
Cholesteatoma of external ear
11.4
42.2
44
39
4122
FHL
Tympanostomy (tympanic tube)
7.1
39.4
59
84
D33.30
ICD-10 Finland
Acoustic neuroma
+∞
37.5
36
*
H73.1
ICD-10 Finland
Chronic myringitis
61.9
37.1
43
7
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
6.8
36.9
57
84
J01DB01
ATC
cefalexin; oral
1.5
36.7
4062
36131
YPA00
NOMESCO Finland
Excision of blood vessel for transplantation
100.8
36.7
40
*
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
10.3
36.0
40
39
H02AB06
ATC
prednisolone; systemic
1.4
35.7
2326
18646
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
35.2
2355
18951
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.2
35.0
325
1560
A98
ICPC
Health maint/preventive medicine
1.9
33.9
4850
45323
J01DA01
ATC
[U] cefalexin
1.4
33.7
2974
25081
H66.2
ICD-10 Finland
Chronic atticoantral suppurative otitis media
120.8
33.7
36
*
H95.0
ICD-10 Finland
Recurrent cholesteatoma of postmastoidectomy cavity
+∞
33.4
32
*
H74.3
ICD-10 Finland
Other acquired abnormalities of ear ossicles
74.6
32.9
37
5
ZXA10
NOMESCO Finland
Bilateral
1.6
32.0
931
6307
DEE00
NOMESCO Finland
Osseous fixation of hearing aid
319.0
31.9
32
*
H95.8
ICD-10 Finland
Other postprocedural disorders of ear and mastoid process
319.0
31.9
32
*
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
2.7
30.8
166
624
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
30.3
1350
9996
DDW99
NOMESCO Finland
Other operation on ossicles of ear
83.1
29.7
33
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
29.5
3272
28387
J01MA02
ATC
ciprofloxacin; systemic
1.4
29.3
1923
15265
SPAT1301
SPAT
No procedures
1.4
29.1
1503
11428
R03AC02
ATC
salbutamol; inhalant
1.4
28.7
2495
20746
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
44.0
28.7
35
8
T16
ICD-10 Finland
Foreign body in ear
5.2
28.3
58
113
J01FA10
ATC
azithromycin; systemic
1.4
28.0
2500
20841
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
28.0
1041
7415
DDD10
NOMESCO Finland
Interposition between malleus and stapes
283.0
27.8
28
*
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.7
27.5
492
2935
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.1
26.9
264
1293
R01AD12
ATC
fluticasone furoate; nasal
1.5
26.5
1229
9133
4151
FHL
Reoperation for chronic otitis media
46.0
26.5
32
7
H70
ICPC
Otitis externa
3.1
26.1
112
372
SPAT1053
SPAT
Memory test
1.6
26.0
764
5164
H80.20
ICD-10 Finland
Otosclerosis involving round window
73.0
25.8
29
*
A02BC02
ATC
pantoprazole; systemic
1.4
25.7
3317
29150
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.8
25.5
366
2045
SPAT1263
SPAT
Sampling
1.4
25.4
1917
15476
R01AD58
ATC
fluticasone, combinations; nasal
1.5
25.3
908
6407
4147
FHL
Radical surgery, cavity filling and middle ear and / or eardrum plastic
22.6
25.2
36
16
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
24.8
1953
15858
S18
ICPC
Laceration/cut
1.4
24.7
2200
18204
SPAT1312
SPAT
General health counselling
1.4
24.6
1394
10714
DE2CM
NOMESCO Finland
Acoustic channel extensive MRI examination with 3 Tesla magnet
48.6
24.3
29
6
TDA90, ,
SPAT
2.1
24.2
237
1160
ZXA05
NOMESCO Finland
Left side
1.4
24.1
1233
9303
3890A
ICD-9 Finland
Deafness, Conductive deafness
+∞
24.0
23
*
38990
ICD-8 Finland
Other deafness, Partialis uni-sive bilateralis
+∞
24.0
23
*
J01AA02
ATC
doxycycline; systemic
1.4
23.9
3757
33848
H25.8
ICD-10 Finland
Other senile cataract
1.6
23.9
589
3819
H02AB04
ATC
methylprednisolone; systemic
1.6
23.9
665
4437
RL210, ,
NOMESCO Finland
6.8
23.8
37
55
DCW99
NOMESCO Finland
Other operation on eardrum and middle ear
31.2
23.7
31
10
DC1AI
NOMESCO Finland
Cone beam CT of ear
87.2
23.7
26
*
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
23.6
3151
27641
AA1AD
NOMESCO Finland
CT of head and brain
1.4
23.4
1334
10249
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
23.3
1581
12507
Z45.3
ICD-10 Finland
Adjustment and management of implanted hearing device
+∞
22.9
22
*
R21
NOMESCO Finland
Counselling and guidance in rehabilitation
4.6
22.8
54
119
SPAT1153
SPAT
Removal of sutures
1.4
22.8
1492
11720
ZXA00
NOMESCO Finland
Right side
1.4
22.7
1319
10159
SPAT1310
SPAT
Counselling related to known health issue
1.4
22.6
1427
11140
P20
ICPC
Memory disturbance
1.5
22.1
705
4840
H71
ICPC
Acute otitis media/myringitis
3.9
22.1
64
165
4143
FHL
Atticotomy or atticoanthromy through the ear canal
52.2
22.1
26
5
M79.6
ICD-10 Finland
Pain in limb
1.3
21.9
1851
15111
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
21.8
2038
16890
H83.1
ICD-10 Finland
Labyrinthine fistula
115.5
21.6
23
*
H61.8
ICD-10 Finland
Other specified disorders of external ear
3.9
21.5
63
164
R1260
NOMESCO Finland
Evaluation of communicative skills
3.2
21.1
84
267
R06.5
ICD-10 Finland
Mouth breathing
1.7
20.9
370
2197
Z01.2
ICD-10 Finland
Dental examination
1.3
20.9
1873
15401
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
20.8
2827
24647
G44.2
ICD-10 Finland
Tension-type headache
1.6
20.8
546
3589
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.3
20.7
1660
13418
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
20.6
909
6653
Q16.1
ICD-10 Finland
Congenital absence, atresia and stricture of auditory canal (external)
110.5
20.6
22
*
H60.1
ICD-10 Finland
Cellulitis of external ear
3.7
20.2
63
171
R05
ICPC
Cough
1.4
20.2
1045
7868
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
20.0
1199
9254
H69.0
ICD-10 Finland
Patulous Eustachian tube
5.0
19.9
42
84
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.3
19.8
1653
13422
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
19.7
1310
10277
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
19.6
1800
14815
H80.28
ICD-10 Finland
Cochlear otosclerosis
200.7
19.6
20
*
R51.80
ICD-10 Finland
Headache
1.5
19.5
595
4040
SPAT1325
SPAT
Vaccination
1.3
19.0
1585
12854
R5599
NOMESCO Finland
Other rehabilitation service
2.4
18.9
129
545
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.5
18.8
630
4364
3891A
ICD-9 Finland
Deafness, Sensorineural deafness
+∞
18.8
18
*
3892A
ICD-9 Finland
Deafness, Mixed conductive and sensorineural deafness
+∞
18.8
18
*
Q16.3
ICD-10 Finland
Congenital malformation of ear ossicles
+∞
18.8
18
*
J31.0
ICD-10 Finland
Chronic rhinitis
1.7
18.7
335
1995
J01FF01
ATC
clindamycin; systemic
1.4
18.6
1203
9382
RK240, ,
NOMESCO Finland
100.4
18.6
20
*
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
18.4
1277
10067
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.5
18.2
644
4508
N17
ICPC
Vertigo/dizziness
1.5
18.2
561
3816
ZYC01
NOMESCO Finland
Remote contact by phone
1.9
18.0
241
1317
UDC10
NOMESCO Finland
Tympanoscopy
33.0
17.9
23
7
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
5.8
17.9
32
55
DEB35
NOMESCO Finland
Radical mastoidectomy with tympanoplasty
+∞
17.7
17
*
DDD20
NOMESCO Finland
Interposition between eardrum and footplate of stapes
+∞
17.7
17
*
G04CA02
ATC
tamsulosin; oral
1.4
17.5
1127
8772
L17
ICPC
Foot/toe symptom/complaint
1.3
17.5
1298
10325
1450
FHL
Otomicroscopy
7.8
17.4
24
31
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
17.2
2348
20275
L15
ICPC
Knee symptom/complaint
1.4
17.1
1037
7989
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.7
17.0
297
1759
SPAT1260
SPAT
Consultation of another employee
1.4
16.9
765
5607
K02.1
ICD-10 Finland
Caries of dentine
1.3
16.9
2444
21236
SFA30
NOMESCO Finland
Three-surface restoration
1.3
16.9
1775
14805
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
16.8
1947
16447
R4130
NOMESCO Finland
Speech therapy
2.3
16.7
128
570
4161
FHL
Exploratory tympanotomy
170.5
16.5
17
*
4144
FHL
Mastoidectomy or aticomastoidectomy
20.1
16.4
24
12
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
16.4
1341
10801
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
16.3
447
2963
J34.2
ICD-10 Finland
Deviated nasal septum
1.9
16.3
209
1127
M25.5
ICD-10 Finland
Pain in joint
1.3
16.2
1311
10535
SPAT1044
SPAT
Tympanometry
2.7
16.2
89
339
H27
ICPC
Fear of ear disease
3.3
16.2
59
178
R06AE07
ATC
cetirizine; oral
1.3
16.2
1864
15709
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
16.2
1772
14842
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.6
16.1
398
2574
UDM02
NOMESCO Finland
Sinoscopy
2.5
16.1
99
399
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
16.0
1185
9402
R03DC03
ATC
montelukast; oral
1.4
15.9
653
4702
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
15.8
1793
15068
J32.4
ICD-10 Finland
Chronic pansinusitis
2.9
15.8
71
243
R74
ICPC
Upper respiratory infection acute
1.3
15.8
1099
8639
Z96.2
ICD-10 Finland
Presence of otological and audiological implants
33.5
15.7
20
6
DEB00
NOMESCO Finland
Cortical mastoidectomy
33.5
15.7
20
6
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
3.4
15.7
56
167
3882A
ICD-9 Finland
Other disorders of ear, Sudden hearing loss, unspecified
+∞
15.6
15
*
DDA10
NOMESCO Finland
Exploration of ossicular chain
+∞
15.6
15
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.7
15.5
291
1757
SFA10
NOMESCO Finland
One-surface restoration
1.3
15.4
2293
19909
R12
ICD-10 Finland
Heartburn
1.6
15.4
324
2014
SFA20
NOMESCO Finland
Two-surface restoration
1.3
15.3
2415
21115
A02BC03
ATC
lansoprazole; oral
1.3
15.2
1296
10475
M54.5
ICD-10 Finland
Low back pain
1.3
15.2
1465
12040
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
15.2
418
2772
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.5
15.1
461
3125
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
15.1
567
4009
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
15.1
1569
13025
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
15.1
1953
16666
Q78.00
ICD-10 Finland
Congenital osteogenesis imperfecta
45.1
15.0
18
*
R05
ICD-10 Finland
Cough
1.4
15.0
912
7012
H92.1
ICD-10 Finland
Otorrhoea
11.8
15.0
27
23
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.7
14.9
281
1699
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
14.8
1439
11832
N06AX11
ATC
mirtazapine; oral
1.3
14.8
1460
12029
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.1
14.8
141
685
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.4
14.8
855
6524
DCB00
NOMESCO Finland
Excision of lesion of middle ear
56.8
14.8
17
*
S02AA03
ATC
boric acid; otic
3.4
14.8
52
154
J01FA09
ATC
clarithromycin; systemic
1.3
14.6
1272
10308
Q17.2
ICD-10 Finland
Microtia
80.3
14.6
16
*
N03AX16
ATC
[U] pregabalin
1.3
14.5
1016
7980
M03BX02
ATC
tizanidine; oral
1.3
14.5
2638
23391
38299
ICD-8 Finland
Unspecified otitis media with mastoiditis
17.0
14.3
22
13
A02BC05
ATC
esomeprazole; systemic
1.3
14.2
1807
15353
J01DA08
ATC
[U] cefaclor
1.6
14.1
366
2393
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
14.1
1012
7972
DE2DG
NOMESCO Finland
Acoustic channel very extensive MRI examination with high intensity magnet
42.6
14.1
17
*
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
14.1
806
6136
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
14.1
1073
8529
D07AC01
ATC
betamethasone; topical
1.3
14.0
1580
13227
H70.0
ICD-10 Finland
Acute mastoiditis
15.8
13.9
22
14
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.0
13.8
147
744
J47
ICD-10 Finland
Bronchiectasis
2.4
13.6
95
407
4139
FHL
Other measure in this category
75.3
13.6
15
*
DCB10
NOMESCO Finland
Freeing of adhesions of middle ear
75.3
13.6
15
*
H60.0
ICD-10 Finland
Abscess of external ear
4.3
13.6
34
79
UKC02
NOMESCO Finland
Cystoscopy
1.4
13.6
756
5729
R06.0
ICD-10 Finland
Dyspnoea
1.3
13.5
1215
9869
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
13.5
4212
39640
H69.8
ICD-10 Finland
Other specified disorders of Eustachian tube
5.2
13.4
27
52
H04.10
ICD-10 Finland
Dry eye syndrome
1.5
13.1
447
3101
J01DA09
ATC
[U] cefadroxil
1.3
13.0
1080
8672
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
13.0
775
5935
38798
ICD-8 Finland
Other disease of ear and mastoid process, Alii definiti
10.0
12.9
25
25
A04
ICPC
Weakness/tiredness general
1.4
12.9
623
4606
J33.0
ICD-10 Finland
Polyp of nasal cavity
2.1
12.9
125
612
WX704
NOMESCO Finland
Intubation
1.6
12.9
332
2170
Q35.1
ICD-10 Finland
Cleft hard palate
50.1
12.8
15
*
R06AX27
ATC
desloratadine; oral
1.3
12.7
1042
8353
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
12.7
1071
8618
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
12.7
777
5973
J01FA06
ATC
roxithromycin; oral
1.3
12.6
1728
14757
4451
FHL
Guitar cutting
3.0
12.6
56
191
J01DA06
ATC
[U] cefuroxime
1.4
12.6
595
4384
R02
ICPC
Shortness of breath/dyspnoea
1.4
12.5
564
4121
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
12.5
810
6277
J20
ICD-10 Finland
Acute bronchitis
1.5
12.4
399
2733
S29
ICPC
Skin symptom/complaint other
1.3
12.4
829
6453
Z98.8
ICD-10 Finland
Other specified postsurgical states
2.7
12.3
64
238
H76
ICPC
Foreign body in ear
3.6
12.3
39
108
H83.3
ICD-10 Finland
Noise effects on inner ear
3.6
12.2
40
113
L12
ICPC
Hand/finger symptom/complaint
1.4
12.2
641
4807
N03AX12
ATC
[U] gabapentin; oral
1.4
12.2
678
5132
WZA90
NOMESCO Finland
Other medical or dental certificate
1.3
12.2
927
7351
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.3
12.0
1051
8490
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.4
12.0
516
3740
C10AA05
ATC
atorvastatin; oral
1.2
12.0
1997
17407
R01AD01
ATC
beclometasone; nasal
1.4
12.0
592
4395
R21
ICPC
Throat symptom/complaint
1.4
11.9
686
5223
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
11.8
961
7687
R01BA51
ATC
phenylpropanolamine, combinations; oral
1.5
11.8
403
2796
R01AD05
ATC
budesonide; nasal
1.6
11.8
299
1947
E0000UV, ,
ATC
1.2
11.8
1773
15276
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
2.5
11.7
71
286
M01AE03
ATC
ketoprofen; systemic, rectal
1.2
11.7
1642
14040
4146
FHL
Radical cutting (bridge broken)
30.1
11.6
15
5
DCA40
NOMESCO Finland
Fat patching or other similar technique without opening of tympanic membrane
30.1
11.6
15
5
G04CB02
ATC
dutasteride; oral
1.5
11.6
343
2309
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
65.1
11.6
13
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.4
11.6
682
5206
DFF40
NOMESCO Finland
Otoneurologic examination of vertigo
5.7
11.5
21
37
H92.2
ICD-10 Finland
Otorrhagia
13.6
11.4
19
14
4129
FHL
Other measure in this category
120.3
11.4
12
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
11.4
1242
10303
WX002
NOMESCO Finland
Sedation and analgesia
1.3
11.4
881
6993
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.3
11.4
848
6696
J33.8
ICD-10 Finland
Other polyp of sinus
2.3
11.4
87
388
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.5
11.4
343
2321
WZC00
NOMESCO Finland
Treatment plan or consultation
1.2
11.3
1528
12999
C07AB07
ATC
bisoprolol; oral
1.2
11.3
2382
21237
38799
ICD-8 Finland
Other disease of ear and mastoid process, Other
35.1
11.3
14
*
R53
ICD-10 Finland
Malaise and fatigue
1.3
11.2
1000
8092
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.3
11.2
700
5392
S02.11
ICD-10 Finland
Fracture of base of skull, open
5.5
11.2
21
38
R03BA05
ATC
fluticasone; inhalant
1.3
11.1
720
5574
SPAT1254
SPAT
Administration of medicine
1.4
11.1
644
4903
N06AX16
ATC
venlafaxine; oral
1.4
11.1
501
3662
SPAT1216
SPAT
Assessment of functional ability
1.3
11.1
710
5489
R5430
NOMESCO Finland
Interpreter's services
8.0
11.0
24
30
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.5
11.0
355
2436
50301
ICD-8 Finland
Chronic sinusitis, Maxillaris NUD
2.7
11.0
56
207
J05AB01
ATC
aciclovir; systemic
1.3
10.9
892
7132
WX720
NOMESCO Finland
Own respiration
1.7
10.9
188
1111
XKD00
NOMESCO Finland
Uroflowmetry
1.3
10.8
714
5540
DJD20
NOMESCO Finland
Plastic repair of septum of nose
1.9
10.8
133
710
J01MA12
ATC
levofloxacin; systemic
1.3
10.8
825
6536
WX722
NOMESCO Finland
PEEP
1.7
10.8
194
1160
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.2
10.8
89
411
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
1.5
10.7
353
2431
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
10.7
1148
9497
SDA03
NOMESCO Finland
Periodontal treatment
1.2
10.7
1544
13216
D11
ICPC
Diarrhoea
1.4
10.6
410
2912
A03
ICPC
Fever
1.4
10.6
571
4294
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.8
10.6
167
962
R03BA08
ATC
ciclesonide; inhalant
1.5
10.6
330
2248
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
10.6
165
948
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
1.7
10.6
186
1106
J45
ICD-10 Finland
Asthma
1.4
10.5
393
2775
RK510, ,
NOMESCO Finland
9.2
10.5
21
23
DCA00
NOMESCO Finland
Biopsy of tympanic membrane or middle ear
110.2
10.4
11
*
H91.3
ICD-10 Finland
Deaf mutism, not elsewhere classified
+∞
10.4
10
*
J45.1
ICD-10 Finland
Nonallergic asthma
1.5
10.4
295
1970
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
10.4
1764
15344
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
1.9
10.4
131
706
DC1BD
NOMESCO Finland
Temporal bone extensive CT
16.0
10.3
16
10
J02AC01
ATC
fluconazole; systemic
1.2
10.3
1533
13147
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.3
10.3
799
6343
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.4
10.2
600
4574
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.6
10.2
246
1584
R01AD11
ATC
triamcinolone; nasal
1.5
10.2
326
2233
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.3
10.1
707
5527
A02BC01
ATC
omeprazole; systemic
1.3
10.0
1206
10099
L08
ICPC
Shoulder symptom/complaint
1.3
10.0
897
7256
J35.2
ICD-10 Finland
Hypertrophy of adenoids
3.0
9.9
42
140
-, ,
ICD-10 Finland
2.0
9.9
97
479
L01
ICPC
Neck symptom/complaint
1.4
9.8
575
4380
H73.8
ICD-10 Finland
Other specified disorders of tympanic membrane
12.2
9.8
17
14
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
9.7
959
7844
M54
ICD-10 Finland
Dorsalgia
1.4
9.7
435
3174
G04BD12
ATC
mirabegron; oral
1.4
9.6
521
3920
DE2BM
NOMESCO Finland
Acoustic channel MRI examination with 3 Tesla magnet
55.1
9.6
11
*
H74.0
ICD-10 Finland
Tympanosclerosis
55.1
9.6
11
*
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.4
9.6
528
3983
C10AA01
ATC
simvastatin; oral
1.2
9.6
2083
18523
ZZG00
NOMESCO Finland
Graft of cartilage
11.4
9.5
17
15
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.3
9.5
735
5826
R13
ICD-10 Finland
Dysphagia
1.5
9.5
283
1910
G04CB01
ATC
finasteride; oral
1.4
9.5
500
3746
P06
ICPC
Sleep disturbance
1.4
9.5
416
3024
M02AA07
ATC
piroxicam; topical
1.2
9.4
1601
13893
EMB30
NOMESCO Finland
Adenotomy
2.8
9.4
45
161
AXX01, ,
SPAT
1.8
9.4
131
729
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
9.4
1704
14885
H95.9
ICD-10 Finland
Postprocedural disorder of ear and mastoid process, unspecified
+∞
9.4
9
*
DED00
NOMESCO Finland
Obliteration of cavity after partial excision of mastoid
+∞
9.4
9
*
H77
ICPC
Perforation ear drum
12.3
9.3
16
13
SPAT1262
SPAT
Handing over of treatment supplies
1.3
9.3
766
6120
-31
ICPC
Medical examin/health eval partial
1.5
9.3
276
1861
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
1.6
9.2
232
1511
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.3
9.1
671
5281
SBB10
NOMESCO Finland
Dental impressions
1.6
9.1
218
1402
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.4
9.1
386
2791
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.4
9.1
486
3653
H93.2
ICD-10 Finland
Other abnormal auditory perceptions
3.5
9.1
30
86
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.5
9.0
292
2005
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.2
9.0
1556
13513
XA410
NOMESCO Finland
BAEP
36.7
9.0
11
*
M79.1
ICD-10 Finland
Myalgia
1.3
9.0
519
3946
SPAT1172
SPAT
Guidance concerning hydration
1.9
9.0
107
567
R35
ICD-10 Finland
Polyuria
1.5
8.9
283
1935
7804A
ICD-9 Finland
General symptoms, Dizziness and giddiness
2.4
8.9
58
242
P03
ICPC
Feeling depressed
1.5
8.9
284
1944
DFF20
NOMESCO Finland
Audiometry for children
18.6
8.9
13
7
-1, ,
NOMESCO Finland
1.2
8.9
1236
10496
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.3
8.9
586
4543
K59.09
ICD-10 Finland
Constipation, unspecified
1.5
8.9
284
1947
H02AB07
ATC
prednisone; oral
1.3
8.9
581
4501
A02BA02
ATC
ranitidine; systemic
1.3
8.8
844
6871
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
1.4
8.8
358
2567
D82
ICPC
Teeth/gum disease
1.2
8.8
1358
11659
WX725
NOMESCO Finland
Noninvasive ventilation
1.6
8.8
207
1328
N06AB10
ATC
escitalopram; oral
1.3
8.8
704
5606
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.2
8.7
1169
9887
N02AX02
ATC
tramadol; systemic, rectal
1.2
8.7
1913
16981
K04.0
ICD-10 Finland
Pulpitis
1.5
8.7
286
1970
M01AE02
ATC
naproxen; oral, rectal
1.2
8.7
2369
21439
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.4
8.6
404
2970
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
1.9
8.6
103
547
DCW00
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
16.3
8.5
13
8
RS220, ,
NOMESCO Finland
2.4
8.5
55
229
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.3
8.5
514
3933
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.3
8.5
542
4180
R00.1
ICD-10 Finland
Bradycardia, unspecified
1.7
8.5
145
857
R29
ICPC
Respiratory symptom/complaint other
1.5
8.5
249
1677
J01DC02
ATC
cefuroxime; systemic
1.6
8.5
197
1260
A28
ICPC
Limited function/disability NOS
1.3
8.4
811
6608
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.5
8.4
255
1730
R96
ICPC
Asthma
1.4
8.4
376
2744
F32
ICD-10 Finland
Depressive episode
1.6
8.4
166
1021
ZXD20
NOMESCO Finland
Day surgery
1.3
8.4
512
3926
3883A
ICD-9 Finland
Other disorders of ear, Tinnitus
+∞
8.3
8
*
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.4
8.3
388
2851
D07AC13
ATC
mometasone; topical
1.2
8.3
1180
10035
J01MA14
ATC
moxifloxacin; systemic
1.4
8.3
365
2657
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.2
8.3
1211
10332
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
1.7
8.2
132
767
S02
ICPC
Pruritus
1.7
8.2
129
745
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.3
8.2
808
6597
S22.3
ICD-10 Finland
Fracture of rib
1.5
8.2
279
1936
SPAT1097
SPAT
Recording of ECG
1.3
8.2
618
4878
C01DA14
ATC
isosorbide mononitrate; oral
1.3
8.2
740
5981
L03
ICPC
Low back symptom/complaint
1.2
8.2
1070
9021
WX400
NOMESCO Finland
Inhalation anesthesy
1.7
8.2
148
890
SGA03
NOMESCO Finland
Opening and preparing the root canals, complicated
1.4
8.1
312
2215
R06AX13
ATC
loratadine; oral
1.3
8.1
511
3938
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.2
8.1
1094
9257
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
2.1
8.1
71
338
R03BA01
ATC
beclometasone; inhalant
1.3
8.0
558
4357
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.2
8.0
1026
8628
3824A
ICD-9 Finland
Suppurative and unspecified otitis media, Unspecified suppurative otitis media
22.0
8.0
11
5
SCD01
NOMESCO Finland
Removal of biofilm and supragingival calculus, short
3.0
8.0
33
109
M01AC06
ATC
meloxicam; systemic, rectal
1.2
7.9
1530
13394
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
7.9
2988
27708
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
1.9
7.9
95
505
L28
ICPC
Limited function/disability (L)
1.3
7.9
806
6605
KMAK, ,
NOMESCO Finland
1.2
7.9
2009
18023
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.3
7.9
677
5434
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.4
7.8
405
3026
SCA01
NOMESCO Finland
Preventive oral health care, short
1.2
7.8
1017
8562
D01
ICPC
Abdominal pain/cramps general
1.4
7.8
416
3123
NF1AA
NOMESCO Finland
Hip X-ray examination
1.4
7.8
381
2822
Z00.0
ICD-10 Finland
General medical examination
1.3
7.8
774
6326
C08CA01
ATC
amlodipine; oral
1.2
7.8
1813
16139
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.2
7.7
1256
10815
M01AB05
ATC
diclofenac; systemic, rectal
1.2
7.7
2888
26735
J01DC04
ATC
cefaclor; oral
2.4
7.7
50
209
0601, ,
NOMESCO Finland
45.0
7.7
9
*
0602, ,
NOMESCO Finland
45.0
7.7
9
*
TDC10
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
15.0
7.7
12
8
C09CA06
ATC
candesartan; oral
1.2
7.7
964
8088
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
7.7
1616
14256
Z02.7
ICD-10 Finland
Issue of medical certificate
1.5
7.6
270
1889
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.5
7.6
248
1707
UJF32
NOMESCO Finland
Coloscopy
1.2
7.6
1119
9540
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.5
7.6
222
1495
SGB10
NOMESCO Finland
Root filling of tooth with one root canal
1.3
7.6
455
3478
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.3
7.6
512
3981
E21.0
ICD-10 Finland
Primary hyperparathyroidism
2.1
7.6
69
333
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
2.4
7.6
50
211
T90
ICPC
Diabetes non-insulin dependent
1.2
7.6
1070
9086
A01AB09
ATC
miconazole; local oral
1.4
7.6
347
2544
M01AX17
ATC
nimesulide; oral
1.2
7.5
1047
8873
A03FA02
ATC
cisapride; oral, rectal
1.4
7.5
314
2264
F83
ICD-10 Finland
Mixed specific developmental disorders
6.1
7.5
19
31
P01AB01
ATC
metronidazole; oral, rectal
1.2
7.5
1620
14314
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.2
7.5
1357
11801
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
7.5
2887
26762
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.5
7.5
225
1525
G51.0
ICD-10 Finland
Bell palsy
1.9
7.5
96
523
N06AB04
ATC
citalopram; systemic
1.2
7.4
846
7021
H86
ICPC
Deafness
80.2
7.4
8
*
Q35.71
ICD-10 Finland
Submucous cleft palate
80.2
7.4
8
*
4364
FHL
Pharyngeal tongue plastic
80.2
7.4
8
*
N01
ICPC
Headache
1.4
7.4
332
2424
WX290
NOMESCO Finland
Other blockage of nerve
1.2
7.4
1678
14886
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
2.3
7.4
51
220
F29
ICPC
Eye symptom/complaint other
1.4
7.4
352
2598
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
1.5
7.4
210
1408
K03.66
ICD-10 Finland
Tooth plaque
1.4
7.4
275
1945
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.3
7.3
602
4804
F06.7
ICD-10 Finland
Mild cognitive disorder
1.7
7.3
123
725
S60.0
ICD-10 Finland
Contusion of finger(s) without damage to nail
1.8
7.3
96
526
R06AX22
ATC
ebastine; oral
1.3
7.3
605
4833
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
7.3
1679
14907
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.4
7.3
315
2285
J37.0
ICD-10 Finland
Chronic laryngitis
1.7
7.3
117
681
R07.3
ICD-10 Finland
Other chest pain
1.4
7.3
401
3026
38920
ICD-8 Finland
Other deafness, Deafness, one ear
+∞
7.3
7
*
DDD30
NOMESCO Finland
Fixation of tympanic membrane to stapes
+∞
7.3
7
*
3897A
ICD-9 Finland
Deafness, Deaf mutism, not elsewhere classifiable[SURDITAS]
+∞
7.3
7
*
3858X
ICD-9 Finland
Other disorders of middle ear and mastoid
+∞
7.3
7
*
3851A
ICD-9 Finland
Other disorders of middle ear and mastoid, Adhesive middle ear disease
+∞
7.3
7
*
H73.9
ICD-10 Finland
Disorder of tympanic membrane, unspecified
10.9
7.3
13
12
R55
ICD-10 Finland
Syncope and collapse
1.3
7.3
464
3580
CS494
NOMESCO Finland
Other visual field testing
1.8
7.3
101
564
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
3.5
7.3
24
69
Z31.5
ICD-10 Finland
Genetic counselling
1.6
7.2
157
989
R44.0
ICD-10 Finland
Auditory hallucinations
3.8
7.2
21
55
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.3
7.2
576
4580
K59.0
ICD-10 Finland
Constipation
1.5
7.2
228
1561
4111
FHL
Ear canal extension
15.7
7.2
11
7
SPAT1215
SPAT
Assessment of need for medical rehabilitation
1.6
7.2
154
967
N06AA10
ATC
nortriptyline; systemic
2.0
7.2
73
367
SPAT1034
SPAT
Removal of foreign body from ear canal
3.7
7.2
22
60
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.2
7.2
1029
8746
DBB00
NOMESCO Finland
Excision of lesion of external auditory canal
4.5
7.2
17
38
G04CA01
ATC
alfuzosin; oral
1.3
7.1
512
4014
Q78.08
ICD-10 Finland
Osteogenesis imperfecta tarda
30.0
7.1
9
*
9560/0-C72.4
ICD-O-3
Schwannoma, NOS, of acoustic nerve
30.0
7.1
9
*
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.4
7.1
275
1956
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
7.1
113
656
R60.0
ICD-10 Finland
Localized oedema
1.3
7.1
520
4087
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
3.0
7.0
29
96
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.4
7.0
340
2518
R03AK08
ATC
formoterol and beclometasone; inhalant
1.6
7.0
156
991
R03BA02
ATC
budesonide; inhalant
1.3
7.0
684
5580
K25
ICPC
Fear of hypertension
1.6
6.9
155
984
C09CA01
ATC
losartan; oral
1.2
6.9
1145
9865
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
1.7
6.9
113
662
K30
ICD-10 Finland
Functional dyspepsia
1.3
6.9
407
3104
D06
ICPC
Abdominal pain localized other
1.4
6.9
304
2214
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.4
6.9
302
2197
ZXE10
NOMESCO Finland
More than one and less than three hours
1.2
6.9
1579
14001
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.3
6.9
527
4167
D07XC01
ATC
betamethasone; topical
1.3
6.9
486
3802
A01
ICPC
Pain general/multiple sites
1.4
6.9
359
2688
R52.9
ICD-10 Finland
Pain, unspecified
1.4
6.9
360
2698
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
1.4
6.8
266
1896
M05BA04
ATC
alendronic acid; oral
1.3
6.8
385
2918
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
1.8
6.8
103
591
H25.1
ICD-10 Finland
Senile nuclear cataract
1.2
6.8
1303
11378
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
1.6
6.8
143
896
SAA04
NOMESCO Finland
Special examination of mouth
1.5
6.8
185
1230
C10AA07
ATC
rosuvastatin; oral
1.2
6.8
1356
11884
DC1AA
NOMESCO Finland
Temporalbone X-ray examination
40.1
6.8
8
*
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
2.5
6.7
41
167
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
2.5
6.7
41
167
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.2
6.7
1064
9124
S16
ICPC
Bruise/contusion
1.7
6.7
124
751
R05FB02
ATC
cough suppressants and expectorants; systemic
1.2
6.7
1627
14491
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.2
6.7
933
7903
H05
ICPC
Bleeding ear
3.2
6.7
25
78
H26.4
ICD-10 Finland
After-cataract
1.3
6.7
447
3472
A97
ICPC
No disease
1.2
6.6
712
5866
R31
ICD-10 Finland
Unspecified haematuria
1.3
6.6
429
3317
WW200, ,
SPAT
1.2
6.6
895
7556
SCA02
NOMESCO Finland
Preventive oral health care
1.4
6.6
332
2473
UJD02
NOMESCO Finland
Gastroscopy
1.5
6.6
194
1311
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.4
6.6
262
1876
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
2.2
6.6
49
219
R01AX03
ATC
ipratropium bromide; nasal
1.8
6.6
92
516
N05AB04
ATC
prochlorperazine; systemic, rectal
1.8
6.5
91
509
W31
ICD-10 Finland
Contact with other and unspecified machinery
1.9
6.5
82
444
DFX03, ,
SPAT
8.7
6.5
13
15
SPAT1211
SPAT
Application of soft bandage
1.4
6.5
343
2571
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.4
6.5
322
2390
3860A
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Ménière's disease
10.0
6.5
12
12
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
1.9
6.5
72
374
N41.0
ICD-10 Finland
Acute prostatitis
1.9
6.5
74
388
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.3
6.5
362
2739
SGA01
NOMESCO Finland
Emergency treatment
1.3
6.4
516
4105
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.3
6.4
622
5063
R06.2
ICD-10 Finland
Wheezing
1.6
6.4
159
1035
75650
ICD-8 Finland
Other congenital anomalies of musculoskeletal system, Chondrodystrophy
69.9
6.4
7
*
Q16.0
ICD-10 Finland
Congenital absence of (ear) auricle
69.9
6.4
7
*
S97
ICPC
Chronic ulcer skin
1.4
6.4
250
1783
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
2.2
6.4
51
234
-59
ICPC
Other therap proced/minor surg NEC
1.7
6.4
107
631
M48.0
ICD-10 Finland
Spinal stenosis
1.3
6.4
518
4125
Z71.8
ICD-10 Finland
Other specified counselling
1.2
6.4
1182
10278
NBG10
NOMESCO Finland
Acromioplastia
1.7
6.4
101
587
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.4
6.4
292
2142
R04.0
ICD-10 Finland
Epistaxis
1.4
6.4
319
2374
J01FA15
ATC
telithromycin; oral
1.3
6.4
352
2660
M70.6
ICD-10 Finland
Trochanteric bursitis
1.3
6.4
519
4139
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.3
6.4
373
2844
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
1.6
6.3
142
904
N30.0
ICD-10 Finland
Acute cystitis
1.3
6.3
634
5184
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.4
6.3
297
2190
Z01.9
ICD-10 Finland
Special examination, unspecified
1.4
6.3
223
1564
G44.1
ICD-10 Finland
Vascular headache, not elsewhere classified
3.2
6.3
24
76
X59
ICD-10 Finland
Exposure to unspecified factor
1.2
6.3
717
5947
D33.39
ICD-10 Finland
Benign tumor of the cranial nerves UNS
+∞
6.2
6
*
H91.0
ICD-10 Finland
Ototoxic hearing loss
+∞
6.2
6
*
H93.0
ICD-10 Finland
Degenerative and vascular disorders of ear
+∞
6.2
6
*
DBD30
NOMESCO Finland
Correction of atresia of external auditory canal
26.7
6.2
8
*
4222
FHL
Endonasal etmoidectomy
2.6
6.2
33
126
XX7FW, ,
NOMESCO Finland
7.0
6.2
14
20
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.4
6.2
302
2238
DFF05, ,
SPAT
2.6
6.2
34
132
78050
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Vertigo
2.1
6.2
53
251
NK1XE
NOMESCO Finland
Other ultrasound examinnation of muscle or tendon
2.5
6.2
37
150
R04
ICPC
Breathing problem other
1.6
6.2
133
839
J01EA01
ATC
trimethoprim; systemic
1.2
6.2
1078
9324
A07AA02
ATC
nystatin; oral
1.4
6.2
233
1654
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
1.7
6.1
107
639
S02.10
ICD-10 Finland
Fracture of base of skull, closed
3.5
6.1
20
57
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
2.8
6.1
29
104
D23.2
ICD-10 Finland
Benign neoplasm: Skin of ear and external auricular canal
2.3
6.1
42
181
R49.01
ICD-10 Finland
Functional dysphonia
1.7
6.1
106
632
ND1AA
NOMESCO Finland
Wrist X-ray examination
1.4
6.1
251
1808
WX402
NOMESCO Finland
General anaesthesia
1.2
6.1
803
6758
L04AD01
ATC
ciclosporin; systemic
2.0
6.1
63
320
SPAT1058
SPAT
PEF monitoring instruction
1.4
6.1
298
2210
A01AB04
ATC
amphotericin B; local oral
1.5
6.1
190
1300
T90.5
ICD-10 Finland
Sequelae of intracranial injury
2.3
6.1
42
182
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
1.6
6.0
134
851
ACC51
NOMESCO Finland
Release of median nerve
1.4
6.0
262
1907
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.3
6.0
358
2737
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.2
6.0
787
6621

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
921
4930
2.05
76.81
2.2
1.8
—
—
—
0
0
800
4835
1.77
43.86
1.7
1.4
—
—
—
0
0
3639
31172
1.54
43.77
4.6
4.1
13.39
13.59
mm/h
0.34
3313
28646
4762
43738
1.93
42.75
20.2
18.2
139.71
139.63
mmol/l
1.39
4637
42623
4768
43835
1.93
42.32
20.4
18.3
3.98
3.98
mmol/l
0.43
4638
42641
4799
44351
1.93
39.89
11.9
10.9
24.90
25.77
u/l
2.51
4557
42644
4320
38851
1.63
38.56
6.6
6.0
40.42
40.29
mmol/mol
0.43
3893
35646
4268
38303
1.60
38.07
5.2
4.7
1.97
2.08
mu/l
1.09
3814
34720
3427
29358
1.48
37.99
5.1
4.5
—
—
—
0
0
4480
40768
1.67
36.85
5.2
4.8
6.02
6.01
mmol/l
0.08
3978
36747
4916
45988
2.05
36.69
25.7
23.0
39.59
39.90
%
1.36
4494
42837
4788
44408
1.87
36.55
20.1
18.4
80.38
79.35
umol/l
1.13
4788
44392
4919
46035
2.05
36.52
25.7
22.9
6.87
6.79
e9/l
0.56
4766
44508
4917
46020
2.04
36.34
25.7
22.9
246.53
247.79
e9/l
0.67
4784
44686
4571
41855
1.70
36.22
17.4
15.6
24.26
25.58
mg/l
1.74
3752
33578
4917
46031
2.04
36.14
25.6
22.8
91.18
91.38
fl
2.25
4832
45276
4917
46031
2.04
36.14
25.6
22.8
30.32
30.37
pg
1.00
4832
45274
4917
46035
2.04
36.07
25.7
22.9
4.44
4.44
e12/l
0.11
4769
44514
4917
46047
2.03
35.85
25.9
23.0
133.71
133.98
g/l
0.61
4830
45306
1697
12802
1.48
35.82
4.3
4.1
—
—
—
0
0
2306
18483
1.44
35.26
2.1
2.0
97.78
94.07
pmol/l
2.64
1179
9498
808
5234
1.64
33.57
5.0
4.7
33.94
32.94
%
1.63
527
3467
3779
33373
1.47
32.94
7.9
7.7
78.48
80.01
u/l
1.19
3524
31401
4645
43082
1.67
30.49
16.8
14.6
—
—
—
0
0
4536
41834
1.61
30.35
5.5
5.1
2.66
2.69
mmol/l
1.24
4077
38161
1187
8639
1.48
28.85
1.7
1.8
1121.57
1171.06
nmol/l
1.01
851
6490
688
4441
1.63
28.66
4.2
4.6
—
—
—
0
0
4429
40824
1.54
27.48
4.9
4.5
4.55
4.60
mmol/l
2.03
3983
37427
2454
20445
1.38
27.38
6.4
6.1
1.22
1.21
mmol/l
2.63
2178
18609
4387
40488
1.50
25.68
4.9
4.5
1.45
1.47
mmol/l
1.43
3926
36879
2047
16747
1.36
24.77
4.2
3.8
38.82
88.41
ng/l
1.09
1492
12188
2642
22539
1.35
24.04
7.2
6.8
1.22
1.21
mmol/l
3.77
2235
19118
3531
31534
1.36
23.44
4.3
4.0
14.98
14.91
pmol/l
1.00
3141
28436
2966
25801
1.34
23.39
5.0
4.7
6.87
6.80
mmol/l
0.91
2786
24192
3238
28564
1.35
23.11
5.1
4.7
662.97
2047.73
e6/l
1.30
39
440
4241
39088
1.44
23.03
4.3
4.0
1.29
1.29
mmol/l
0.24
3766
35253
2347
19869
1.33
21.60
7.1
6.4
—
—
—
0
0
1669
13442
1.35
21.54
2.7
2.6
57.59
64.85
u/l
0.62
1524
12383
2546
21881
1.32
20.72
6.6
6.0
0.20
0.19
e9/l
0.21
2216
18899
2645
22909
1.31
20.09
6.1
6.4
11.41
11.74
umol/l
0.60
2493
21777
2491
21401
1.31
20.07
17.8
16.6
1.28
1.30
inr
0.53
678
6057
1671
13607
1.33
19.60
3.2
3.1
1489.38
1638.51
ng/l
0.78
1418
11817
2390
20506
1.30
19.08
7.0
6.2
27.23
27.02
%
0.41
2220
19079
2081
17539
1.31
18.91
2.4
2.2
78.55
78.50
nmol/l
0.03
1818
15567
2332
19960
1.30
18.89
6.8
6.1
2.88
2.84
%
0.31
2155
18507
2343
20067
1.30
18.88
7.3
6.4
8.78
8.75
%
0.19
2167
18632
2353
20200
1.30
18.49
6.7
5.9
57.36
57.87
%
1.22
2181
18780
2504
21699
1.29
18.21
6.5
5.9
1.91
1.90
e9/l
0.05
2219
18881
2446
21146
1.29
18.06
6.4
5.8
0.61
0.60
e9/l
0.36
2135
17993
1409
11305
1.34
17.96
2.4
2.3
2.98
2.99
mg/l
0.06
1170
9618
2452
21219
1.29
17.90
6.4
5.8
0.04
0.04
e9/l
1.20
2137
18044
1760
14590
1.31
17.76
5.3
5.2
2.72
3.55
ug/l
1.38
1536
12953
842
6254
1.41
17.32
2.0
2.0
—
—
—
0
0
2042
17310
1.29
17.29
3.0
2.9
147.78
141.93
ug/l
0.29
1841
15905
1319
10571
1.33
16.73
1.6
1.6
20.96
20.18
nmol/l
0.94
1085
9033
328
2016
1.67
16.32
3.8
4.1
—
—
—
0
0
289
1721
1.72
16.18
4.1
4.3
24.94
24.88
mmol/l
0.14
266
1569
2242
19369
1.27
15.89
6.9
6.1
0.71
0.67
%
3.40
2068
17940
1701
14204
1.29
15.79
4.0
3.8
7.92
9.29
mg/mmol
0.62
1007
8939
1936
16507
1.27
15.02
3.9
3.5
5.91
5.81
ph
0.47
90
945
1668
14028
1.28
14.29
3.5
3.2
7.09
7.29
mmol/l
1.18
1374
11705
2368
20820
1.25
13.72
4.3
3.8
0.00
0.00
estimate
0.50
357
3718
2899
26080
1.25
13.65
3.3
3.1
53.57
51.76
u/l
0.36
2641
23955
2225
19450
1.25
13.49
5.1
4.9
35.12
34.97
g/l
0.63
2036
18000
2341
20584
1.25
13.46
4.3
3.8
0.00
0.00
estimate
0.05
393
4083
1670
14160
1.26
13.11
3.4
3.3
—
—
—
0
0
2336
20578
1.24
13.07
5.7
5.1
0.00
0.00
estimate
0.80
359
3803
1506
12635
1.27
12.87
4.4
4.4
—
—
—
0
0
234
1403
1.70
12.82
5.4
6.1
1.51
1.29
mmol/l
1.26
215
1236
1154
9370
1.30
12.79
1.7
1.7
28118609.07
27238999.34
pmol/l
0.02
914
7717
2756
24765
1.24
12.68
9.3
9.2
4.17
4.18
e9/l
0.06
2439
21381
938
7437
1.32
12.35
1.4
1.5
2.53
2.53
g/l
0.03
525
4306
1105
8958
1.30
12.34
4.4
4.2
1.02
1.02
kg/l
0.11
137
1420
1590
13486
1.26
12.26
3.5
3.2
787.79
330.69
mg/l
1.90
955
8606
411
2848
1.48
12.11
4.0
3.9
5.22
5.15
kpa
0.90
390
2704
1038
8402
1.29
11.65
1.3
1.2
1.95
1.85
u/ml
0.08
241
2122
404
2813
1.47
11.62
4.0
3.9
7.43
7.42
ph
0.49
37
364
853
6740
1.32
11.43
1.3
1.3
35.05
36.29
iu/ml
0.06
278
2131
347
2364
1.50
11.12
2.5
2.4
—
—
—
0
0
1575
13492
1.24
10.82
2.3
2.1
170.57
205.49
u/l
1.64
1446
12604
282
1869
1.54
10.30
4.9
5.1
1.69
1.63
%
0.31
266
1739
1326
11202
1.25
10.24
1.7
1.6
1.37
1.35
mmol/l
0.23
1093
9348
103
514
2.02
10.19
2.0
2.1
28.81
24.68
mg/l
0.26
26
131
415
2980
1.43
10.14
1.6
1.4
—
—
—
0
0
393
2795
1.44
10.12
2.6
3.1
5.93
5.49
e9/l
0.17
282
2193
1373
11676
1.24
9.93
4.8
4.4
22.29
22.08
%
0.21
697
5996
278
1853
1.53
9.90
5.0
5.1
0.94
0.87
%
1.77
262
1731
402
2884
1.43
9.87
6.8
6.9
24.61
24.67
mmol/l
0.11
385
2732
169
998
1.72
9.87
6.1
7.0
11.08
11.18
mmol/l
0.13
153
884
169
999
1.71
9.83
6.1
7.0
105.48
105.04
mmol/l
0.51
153
885
1338
11381
1.24
9.61
3.0
2.8
4498.44
5325.41
umol/l
0.30
1142
9800
788
6316
1.29
9.37
1.3
1.2
10.91
13.89
u/ml
0.68
292
2337
419
3079
1.39
8.97
3.3
2.7
10.36
10.49
g/l
0.23
385
2822
1952
17359
1.20
8.73
2.2
2.2
—
—
—
0
0
1727
15187
1.20
8.72
3.2
3.5
2.35
2.36
mmol/l
0.30
1441
13266
411
3037
1.38
8.51
1.2
1.2
—
—
—
0
0
1183
10043
1.23
8.50
4.1
3.7
—
—
—
0
0
579
4516
1.32
8.40
2.1
2.2
146.50
152.36
ug/g
0.13
434
3515
661
5252
1.30
8.36
1.4
1.3
526.03
490.50
titre
0.20
146
1147
1252
10756
1.22
7.92
2.8
2.4
—
—
—
0
0
2237
20254
1.18
7.90
3.0
2.6
—
—
—
0
0
41
154
2.68
7.88
1.0
1.1
1.74
6.68
u/ml
—
8
18
1595
14060
1.19
7.61
2.8
2.5
—
—
—
0
0
720
5853
1.27
7.56
1.3
1.2
—
—
—
0
0
466
3591
1.33
7.36
3.7
3.6
—
—
—
0
0
115
671
1.73
7.12
3.1
2.4
—
—
—
0
0
309
2258
1.39
6.88
1.4
1.3
181.88
229.77
u/ml
0.96
287
2059
512
4057
1.29
6.60
2.8
2.5
70.40
69.59
e9/l
0.18
399
3012
318
2360
1.37
6.46
1.3
1.3
35.73
58.45
au/ml
1.07
13
135
1264
11060
1.19
6.37
4.6
4.2
0.00
0.00
estimate
1.34
352
3657
259
1866
1.41
6.29
2.2
1.5
8.33
21.96
u/ml
1.65
13
51
522
4189
1.27
6.08
2.9
2.9
177.74
215.14
ng/l
1.59
478
3818
447
3532
1.29
5.90
4.0
3.8
99.56
92.93
ng/l
0.60
373
3013
320
2424
1.34
5.73
1.8
1.8
1.21
1.34
g/l
0.50
285
2191
3204
30271
1.15
5.57
4.3
4.0
—
—
—
0
0
340
2626
1.32
5.34
2.5
2.4
11.86
23.06
au/ml
2.64
17
173
188
1325
1.43
5.22
11.5
10.2
—
—
—
0
0
210
1510
1.41
5.22
1.3
1.2
0.20
1.04
u/ml
1.98
24
139
392
3097
1.29
5.20
5.0
4.7
—
—
—
0
0
292
2225
1.33
5.05
3.9
3.4
25.23
25.25
mmol/l
0.04
286
2159
1044
9160
1.17
4.96
1.7
1.7
1.29
1.36
mg/l
0.20
813
7099
85
513
1.67
4.79
2.5
2.8
—
—
—
0
0
43
211
2.05
4.66
11.3
13.8
—
—
—
0
0
70
405
1.74
4.61
2.7
3.0
40.69
50.39
mg/l
0.18
46
302
80
482
1.67
4.55
3.8
4.4
—
—
—
0
0
3734
35853
1.14
4.55
19.8
18.6
15.57
15.11
%
3.88
3668
35173
638
5402
1.21
4.54
2.7
2.5
1.83
1.78
%
0.46
539
4765
77
463
1.67
4.43
4.4
3.7
59.23
56.16
%
0.60
64
383
87
540
1.62
4.42
1.4
1.6
59.62
59.69
%
0.01
55
343
284
2201
1.31
4.40
1.3
1.3
—
—
—
0
0
708
6073
1.19
4.37
6.2
5.9
1.04
1.04
mmol/l
0.28
650
5598
111
732
1.53
4.36
2.0
1.9
4.52
4.83
mmol/24h
0.45
95
631
79
481
1.65
4.34
1.4
1.2
—
—
—
0
0
191
1401
1.38
4.28
1.6
1.6
—
—
—
0
0
575
4850
1.21
4.26
6.7
7.3
95.50
95.51
%
0.01
546
4663
140
977
1.44
4.18
1.3
1.3
490.09
529.73
mg/l
0.59
131
924
206
1542
1.35
4.08
3.2
3.1
0.30
0.30
g/l
0.00
83
646
320
2549
1.27
4.03
8.0
9.2
—
—
—
0
0
47
254
1.86
3.92
2.0
2.4
0.25
0.21
e9/l
0.81
42
221
248
1921
1.31
3.89
2.1
1.9
1.21
2.53
ug/l
2.09
213
1689
344
2781
1.25
3.84
4.0
3.3
126.58
128.16
g/l
0.66
337
2709
123
853
1.45
3.83
1.4
1.5
318.05
1229.63
e6/l
1.77
107
688
116
796
1.47
3.81
1.3
1.4
—
—
—
0
0
124
862
1.45
3.81
1.2
1.3
3.94
3.84
mmol/l
0.43
114
810
813
7140
1.16
3.77
2.6
2.6
12.30
12.49
umol/l
0.33
753
6639
62
371
1.68
3.69
1.2
1.1
—
—
—
0
0
1009
9018
1.15
3.67
4.0
3.8
431.19
511.69
ng/l
0.18
807
7425
524
4449
1.20
3.64
7.0
7.6
120.72
120.37
g/l
0.15
508
4319
629
5430
1.18
3.61
6.6
6.9
1.33
1.06
mmol/l
1.01
491
4295
150
1091
1.39
3.60
2.0
1.9
13.44
11.32
mg/l
0.62
137
1008
264
2087
1.28
3.57
3.6
2.7
0.68
0.65
%
1.01
264
2074
630
5451
1.18
3.52
6.6
6.9
11.82
12.22
kpa
1.35
596
5169
630
5454
1.18
3.50
6.6
6.9
5.11
5.10
kpa
0.05
597
5172
162
1201
1.36
3.47
1.8
1.4
11.66
16.72
iu/ml
—
7
25
47
265
1.78
3.47
1.9
2.4
471.80
484.04
e6/l
0.08
41
221
62
379
1.64
3.43
1.3
1.3
7.03
6.94
g/l
0.07
48
264
62
379
1.64
3.43
1.3
1.3
2.95
2.91
g/l
0.08
49
264
62
379
1.64
3.43
1.3
1.3
0.41
0.42
g/l
0.08
50
265
30
146
2.06
3.41
2.1
1.9
62.59
56.07
ug/l
0.12
30
141
62
380
1.64
3.40
1.4
1.3
—
—
—
0
0
232
1817
1.29
3.40
5.6
4.7
—
—
—
0
0
46
260
1.78
3.37
1.3
1.3
0.68
1.28
u/ml
0.40
29
138
70
444
1.58
3.35
1.2
1.1
—
—
—
0
0
149
1097
1.37
3.35
1.5
1.6
12755.77
13135.14
e6/l
0.03
111
769
120
852
1.42
3.34
1.3
1.4
119.13
20.95
e6/l
0.50
99
651
1474
13570
1.12
3.32
4.5
4.1
7.40
7.40
ph
0.06
234
2553
73
472
1.55
3.23
1.2
1.2
—
—
—
0
0
3593
34690
1.11
3.22
23.1
20.3
331.83
331.72
g/l
0.23
3571
34366
92
626
1.48
3.21
1.5
1.5
0.72
0.82
g/l
0.48
71
475
1464
13501
1.12
3.18
3.6
3.3
31.90
36.32
u/l
1.25
1391
12730
19
79
2.41
3.13
1.0
1.0
4.76
14.62
u/ml
—
6
49
9
20
4.51
3.11
1.3
1.3
—
—
—
0
0
97
672
1.45
3.10
2.6
1.3
—
—
—
0
0
63
398
1.59
3.09
2.1
2.3
1.16
1.09
e9/l
0.29
58
356
203
1586
1.29
3.06
1.9
2.2
275.27
503.04
ug/l
2.92
185
1502
27
132
2.05
3.06
1.9
1.9
—
—
—
0
0
160
1216
1.33
2.96
1.4
1.4
—
—
—
0
0
744
6608
1.15
2.96
2.7
2.5
2.35
2.29
g/l
2.35
682
6116
534
4629
1.17
2.94
1.3
1.3
—
—
—
0
0
138
1031
1.35
2.88
1.7
1.7
—
—
—
0
0
41
237
1.74
2.84
1.6
2.3
21.32
25.60
umol/l
—
5
17
702
6235
1.15
2.79
2.7
2.6
21.14
21.95
%
0.87
573
5343
477
4119
1.17
2.77
2.4
2.3
6.86
7.27
ug/l
0.16
374
3566
328
2741
1.21
2.76
1.3
1.2
—
—
—
0
0
144
1092
1.33
2.73
1.0
1.1
—
—
—
0
0
274
2256
1.23
2.68
1.7
1.7
1.60
1.56
g/l
0.23
222
1941
615
5435
1.15
2.64
1.7
1.7
—
—
—
0
0
84
587
1.44
2.62
2.2
2.4
—
—
—
0
0
88
625
1.41
2.53
5.7
6.2
11.01
11.99
mg/l
1.32
82
568
482
4198
1.16
2.53
1.6
1.6
—
—
—
0
0
41
246
1.67
2.52
3.3
3.1
—
—
—
0
0
25
129
1.94
2.49
1.6
1.4
79.69
231.78
nmol/24h
0.93
25
129
67
453
1.49
2.49
1.0
1.1
0.14
1.18
u/ml
2.93
22
196
20
95
2.11
2.48
1.5
2.3
191.54
154.69
e6/l
0.33
13
49
34
195
1.75
2.46
1.5
1.6
—
—
—
0
0
236
1933
1.23
2.45
1.2
1.2
—
—
—
0
0
50
319
1.57
2.43
1.0
1.1
1.88
3.16
u/ml
0.83
18
129
492
4310
1.16
2.40
2.3
2.2
0.21
0.21
g/l
0.17
451
4003
84
599
1.41
2.38
2.2
2.4
4.07
4.09
mmol/l
0.19
84
592
84
599
1.41
2.38
2.2
2.4
105.00
105.28
mmol/l
0.22
84
592
149
1161
1.29
2.37
4.3
3.5
—
—
—
0
0
23
118
1.95
2.35
1.1
1.3
38.23
33.01
%
0.24
13
80
104
771
1.36
2.34
4.6
3.6
1.55
1.57
%
0.02
90
677
1208
11190
1.10
2.34
7.1
6.8
—
—
—
0
0
45
283
1.60
2.33
1.4
2.0
4.44
7.00
umol/l
1.39
30
197
277
2322
1.20
2.30
3.1
2.8
0.26
0.31
e6/l
0.32
270
2275
149
1169
1.28
2.26
1.4
1.4
31.88
31.52
iu/l
0.04
129
984
49
318
1.55
2.23
1.0
1.0
707.24
702.87
ng/l
0.03
34
214
189
1530
1.24
2.22
3.8
3.3
5.72
3.51
ratio
0.24
15
119
76
541
1.41
2.20
1.1
1.1
2.83
2.13
u/ml
0.10
34
284
383
3317
1.17
2.19
2.4
2.4
—
—
—
0
0
59
401
1.48
2.18
1.8
1.7
1053.33
1249.23
titre
—
6
13
26
143
1.82
2.18
1.2
1.2
—
—
—
0
0
1150
10672
1.10
2.14
4.1
3.5
—
—
—
0
0
193
1575
1.23
2.12
3.8
3.3
42.26
51.03
mg/l
0.38
158
1292
21
109
1.93
2.10
1.1
1.1
—
—
—
0
0
20
102
1.96
2.10
2.0
2.0
—
—
—
0
0
95
710
1.34
2.07
1.4
1.6
—
—
—
0
0
42
269
1.57
2.05
1.2
1.1
—
—
—
0
0
20
103
1.95
2.05
6.1
4.9
—
—
—
0
0
48
319
1.51
2.00
1.0
1.0
339.41
321.10
ng/l
0.19
34
221
192
1578
1.22
1.99
3.8
3.3
81.80
92.15
mg/l
0.09
157
1300
150
1202
1.26
1.96
1.7
1.7
—
—
—
0
0
454
4023
1.14
1.93
2.7
2.6
65.36
66.11
g/l
1.17
404
3626
63
446
1.42
1.92
1.5
1.7
—
—
—
0
0
22
120
1.84
1.92
1.3
1.1
—
—
—
0
0
21
113
1.86
1.91
1.0
1.0
—
—
—
0
0
66
472
1.40
1.91
1.0
1.0
1.13
4.21
u/ml
4.10
26
239
646
5858
1.12
1.88
6.8
6.8
104.38
104.39
mmol/l
0.02
646
5853
95
727
1.31
1.80
1.3
1.4
—
—
—
0
0
280
2408
1.17
1.80
3.1
3.3
4.44
4.42
pmol/l
0.09
242
2103
50
344
1.46
1.79
1.2
1.2
—
—
—
0
0
422
3742
1.14
1.79
2.3
2.3
368.63
379.48
nmol/l
0.45
374
3430
11
47
2.34
1.77
1.1
1.0
46.00
47.57
%
—
5
21
45
304
1.48
1.77
1.3
1.3
2.48
2.14
mmol/l
0.41
40
286
823
7588
1.10
1.75
3.5
3.3
0.82
0.81
mmol/l
0.30
752
7090
40
264
1.52
1.75
1.1
1.2
35.68
43.42
mg/l
1.08
33
223
170
1402
1.22
1.74
4.5
4.2
3.89
3.89
mmol/l
0.02
170
1386
102
793
1.29
1.74
2.0
1.8
—
—
—
0
0
491
4410
1.13
1.71
4.6
3.8
1.92
1.97
mmol/l
0.10
414
3725
105
823
1.28
1.69
1.5
1.5
—
—
—
0
0
51
358
1.43
1.67
2.4
2.4
—
—
—
0
0
520
4696
1.12
1.66
1.6
1.5
—
—
—
0
0
103
808
1.28
1.65
3.0
1.9
—
—
—
0
0
83
633
1.32
1.64
3.8
2.7
—
—
—
0
0
103
810
1.28
1.63
3.0
1.8
—
—
—
0
0
119
954
1.25
1.61
4.3
3.6
30.25
28.11
mg/l
0.23
72
613
59
429
1.38
1.60
1.1
1.0
1.68
1.40
u/ml
0.11
27
227
39
263
1.49
1.57
2.4
2.3
0.09
0.19
e9/l
0.79
39
250
119
957
1.25
1.57
1.1
1.1
19.19
6.51
u/ml
—
7
95
38
255
1.49
1.57
1.1
1.1
259.97
286.65
mg/l
0.55
33
224
103
816
1.27
1.55
3.0
1.8
—
—
—
0
0
143
1176
1.22
1.54
1.7
1.5
0.23
0.24
g/l
0.41
137
1111
125
1015
1.24
1.52
3.1
3.1
0.80
0.84
nmol/l
0.38
101
777
414
3711
1.13
1.52
4.7
4.0
1.03
0.96
%
0.23
167
1337
34
225
1.51
1.51
3.5
2.7
41.54
38.62
%
0.39
22
121
121
981
1.24
1.50
1.3
1.2
4.15
6.38
u/ml
0.25
13
97
95
749
1.27
1.49
3.2
1.9
—
—
—
0
0
122
991
1.24
1.49
1.4
1.3
9.11
5.66
u/ml
0.35
21
145
552
5034
1.11
1.49
2.7
2.8
6.88
9.05
umol/l
2.39
476
4362
58
427
1.36
1.48
1.3
1.4
99436.82
102538.60
e6/l
0.01
38
285
38
259
1.47
1.47
1.8
1.5
—
—
—
0
0
44
309
1.43
1.47
1.6
1.6
—
—
—
0
0
49
351
1.40
1.47
1.1
1.1
5.62
2.35
u/ml
0.61
18
170
909
8498
1.08
1.44
3.2
3.1
0.74
0.80
ug/l
0.87
642
5973
142
1178
1.21
1.43
6.5
4.3
—
—
—
0
0
447
4042
1.12
1.42
1.6
1.5
—
—
—
0
0
16
88
1.82
1.41
1.1
1.2
—
—
—
0
0
53
388
1.37
1.41
1.2
1.2
327.64
365.53
nmol/l
0.63
42
313
627
5773
1.10
1.40
1.3
1.3
—
—
—
0
0
72
553
1.31
1.40
3.8
4.8
384.52
356.12
umol/l
0.82
62
476
215
1855
1.17
1.39
2.7
2.7
—
—
—
0
0
421
3802
1.12
1.38
1.5
1.5
—
—
—
0
0
6
23
2.61
1.36
1.0
1.0
—
—
—
0
0
226
1962
1.16
1.36
1.8
2.0
—
—
—
0
0
68
521
1.31
1.35
3.9
19.5
7.30
7.42
mmol/l
0.10
54
436
145
1216
1.20
1.32
1.6
1.5
1.17
1.19
g/l
0.27
140
1149
11
54
2.04
1.32
2.3
2.9
—
37.89
—
0
10
147
1236
1.19
1.31
1.2
1.2
—
—
—
0
0
132
1099
1.21
1.30
1.2
1.2
74.29
92.66
titre
—
7
94
17
98
1.74
1.30
1.1
1.4
—
—
—
0
0
95
766
1.24
1.28
1.6
1.4
—
—
—
0
0
25
162
1.55
1.25
2.6
2.2
52.71
54.11
umol/l
0.07
14
132
126
1055
1.20
1.20
1.3
1.2
14.24
37.22
u/ml
—
8
58
55
418
1.32
1.19
1.5
1.3
—
—
—
0
0
763
7142
1.08
1.19
2.0
2.0
29.52
29.89
s
1.11
729
6944
25
165
1.52
1.17
1.4
2.1
4933.78
839.92
e6/l
0.50
18
115
39
282
1.39
1.16
3.0
3.4
—
—
—
0
0
34
240
1.42
1.15
1.3
1.3
1.20
1.21
nmol/l
0.02
26
181
480
4412
1.10
1.15
4.8
3.8
5.92
5.85
kpa
0.82
471
4272
66
521
1.27
1.10
1.8
2.0
—
—
—
0
0
16
96
1.67
1.10
3.5
2.5
—
—
—
0
0
5
21
2.38
1.09
3.8
1.8
—
—
—
0
0
14
81
1.73
1.08
3.0
6.5
—
—
—
0
0
34
468
0.72
1.08
1.1
1.1
—
—
—
0
0
1066
11202
0.94
1.07
1.4
1.4
—
—
—
0
0
346
3803
0.90
1.07
4.3
4.0
1.23
1.23
mmol/l
0.14
298
3313
33
236
1.40
1.06
1.1
1.1
—
—
—
0
0
18
113
1.59
1.05
1.2
1.9
0.07
1.30
mmol/l
0.80
18
103
37
499
0.74
1.05
1.0
1.2
—
—
—
0
0
25
170
1.47
1.04
2.3
2.1
—
—
—
0
0
24
162
1.48
1.04
3.5
2.3
—
—
—
0
0
394
3610
1.10
1.03
4.1
3.2
4.32
4.53
kpa
1.66
383
3479
27
187
1.45
1.03
2.0
1.6
4.10
7.38
nmol/l
0.66
22
159
37
272
1.36
1.02
2.0
2.5
7.46
7.42
ph
—
10
95
9
47
1.92
1.02
1.8
2.9
—
—
—
0
0
42
316
1.33
1.01
1.2
1.2
—
—
—
0
0
78
636
1.23
1.00
3.5
1.8
—
—
—
0
0
123
1048
1.18
1.00
2.1
2.2
129.99
127.52
g/l
0.49
86
755
128
1492
0.85
1.00
1.6
1.7
—
—
—
0
0
191
1683
1.14
1.00
1.1
1.1
110.00
199.61
titre
—
7
38
371
3396
1.10
1.00
4.6
3.8
0.76
0.68
%
0.29
140
1158
305
2765
1.11
0.99
2.2
2.1
13.05
12.13
nmol/l
0.95
254
2426
17
107
1.59
0.99
1.1
1.1
—
—
—
0
0
42
317
1.33
0.99
1.3
1.7
1835.89
1868.67
ml
0.09
36
311
9
49
1.84
0.98
2.6
2.6
1.10
1.67
mg/l
—
9
34
98
1164
0.84
0.97
1.1
1.1
—
—
—
0
0
15
92
1.63
0.97
1.4
1.4
—
—
—
0
0
0
31
0.00
0.96
0.0
1.7
—
0.79
—
0
20
35
468
0.75
0.95
1.1
1.1
—
—
—
0
0
49
381
1.29
0.95
1.2
1.5
0.29
0.30
nmol/l
0.07
33
288
46
356
1.29
0.92
1.7
1.3
—
—
—
0
0
19
126
1.51
0.91
1.9
1.4
—
—
—
0
0
23
159
1.45
0.91
1.6
1.5
—
—
—
0
0
156
1775
0.88
0.90
3.1
3.4
153.96
3673.00
u/ml
1.45
133
1505
6
29
2.07
0.89
1.0
1.1
—
—
—
0
0
215
1929
1.12
0.87
2.6
2.2
7.56
7.54
g/l
0.07
183
1727
10
56
1.79
0.87
1.3
1.5
—
—
—
0
0
386
4171
0.92
0.87
1.4
1.4
—
—
—
0
0
97
823
1.18
0.86
1.2
1.7
0.82
0.82
nmol/l
0.03
78
688
11
64
1.72
0.86
1.6
2.1
2.70
2.73
mmol/l
0.02
11
57
287
2619
1.10
0.86
1.5
1.4
—
—
—
0
0
214
1924
1.12
0.85
2.6
2.2
3.62
3.74
g/l
0.37
183
1723
8
45
1.78
0.84
1.1
1.2
—
—
—
0
0
381
3529
1.09
0.83
4.6
4.0
0.13
0.12
%
0.05
136
1161
157
1771
0.88
0.82
1.5
1.5
—
—
—
0
0
60
489
1.23
0.82
1.3
1.3
—
—
nmol/l
—
0
0
202
1815
1.12
0.82
2.6
2.3
2.84
3.03
g/l
1.87
170
1615
15
97
1.55
0.81
6.2
7.0
—
—
—
0
0
18
122
1.48
0.80
1.1
1.1
—
—
—
0
0
27
198
1.37
0.80
2.7
3.1
30.00
25.14
mu/l
0.22
27
191
58
473
1.23
0.79
1.3
1.2
—
—
—
0
0
8
48
1.67
0.78
1.8
2.1
18.90
18.77
umol/l
—
8
48
86
730
1.18
0.78
2.2
2.1
5882.34
3444.17
u/l
0.32
29
296
23
316
0.73
0.78
1.2
1.1
—
—
—
0
0
456
4266
1.08
0.78
7.5
7.2
10.91
10.46
mmol/l
0.63
436
4057
66
547
1.21
0.78
2.7
2.5
1.43
1.26
g/24h
0.16
32
270
24
326
0.73
0.76
2.7
2.1
2.19
2.22
ug/l
0.02
19
277
80
677
1.18
0.76
1.6
1.4
107.35
120.00
u/ml
0.58
23
130
37
288
1.29
0.75
1.0
1.0
0.02
0.23
u/ml
—
5
97
98
845
1.16
0.75
1.4
1.3
158.10
211.47
miu/ml
0.64
31
349
10
161
0.62
0.75
1.2
1.4
—
—
—
0
0
25
184
1.36
0.73
2.5
2.7
—
—
—
0
0
7
39
1.80
0.72
1.4
1.3
—
—
—
0
0
6
107
0.56
0.72
1.0
1.0
—
—
—
0
0
903
8656
1.05
0.72
3.0
3.2
2.46
2.46
mmol/l
0.44
800
7550
199
1804
1.11
0.71
2.4
2.2
9.56
10.23
g/l
1.58
164
1586
9
57
1.58
0.71
2.3
1.7
—
—
—
0
0
5
26
1.92
0.70
3.2
3.0
—
—
—
0
0
79
675
1.17
0.69
1.3
1.2
314.61
282.95
u/ml
0.37
47
418
24
179
1.34
0.66
2.4
2.1
5.75
7.76
%
0.55
24
170
19
136
1.40
0.66
1.2
1.1
39.71
39.65
g/l
—
7
75
52
430
1.21
0.65
1.5
1.4
25.29
26.07
iu/ml
—
7
15
70
596
1.18
0.65
1.3
1.3
—
—
—
0
0
7
44
1.59
0.65
1.1
1.1
1.70
1.68
umol/24h
—
7
44
50
413
1.21
0.64
1.2
1.2
—
—
—
0
0
315
2935
1.08
0.64
3.2
3.1
—
—
—
0
0
38
305
1.25
0.63
1.1
1.0
281.41
290.55
mg/l
0.36
32
276
91
794
1.15
0.63
1.4
1.4
10.40
11.03
u/l
0.16
69
647
233
2527
0.92
0.62
1.4
1.4
—
—
—
0
0
949
9146
1.05
0.62
3.6
2.9
539.76
540.95
mosm/kgh2o
0.06
790
7810
999
9647
1.04
0.60
2.9
2.7
5.36
5.37
e6/l
0.01
879
8612
355
3335
1.07
0.59
4.7
4.0
1.32
0.29
%
0.67
118
966
233
2154
1.09
0.59
1.7
1.6
—
—
—
0
0
822
7913
1.05
0.57
3.2
2.8
1.34
1.52
e6/l
0.19
493
4521
139
1256
1.11
0.57
1.9
2.5
3.79
3.62
g/l
0.58
129
1198
21
158
1.33
0.57
1.1
1.2
—
—
—
0
0
253
2351
1.08
0.57
4.9
3.5
—
—
—
0
0
64
549
1.17
0.57
5.5
2.5
—
—
—
0
0
30
238
1.26
0.56
1.6
1.7
2.70
2.75
u/field
0.02
23
171
48
402
1.20
0.56
1.4
1.3
23.79
30.13
u/l
0.79
34
330
26
330
0.79
0.56
2.3
2.4
—
—
—
0
0
76
662
1.15
0.56
1.4
1.3
—
—
—
0
0
40
329
1.22
0.55
1.5
1.1
—
225.00
—
0
12
40
329
1.22
0.55
1.5
1.1
90.00
177.24
titre
—
9
58
6
37
1.62
0.55
1.0
1.1
—
—
—
0
0
16
217
0.74
0.55
1.2
1.4
1.51
1.57
g/l
0.54
16
217
403
4253
0.94
0.53
2.5
2.4
37.50
49.92
u/l
0.51
351
3625
62
534
1.16
0.53
1.2
1.3
—
—
—
0
0
153
1396
1.10
0.53
1.1
1.1
—
—
—
0
0
9
62
1.45
0.53
1.8
1.4
—
—
—
0
0
48
405
1.19
0.52
1.3
1.5
35.40
29.57
%
0.38
26
246
9
132
0.68
0.51
1.0
1.0
—
0.92
—
0
36
85
959
0.88
0.51
1.4
1.3
—
—
—
0
0
67
768
0.87
0.51
4.2
3.3
—
—
—
0
0
9
64
1.41
0.51
11.3
12.5
5.93
5.50
mmol/l
—
9
64
374
3540
1.06
0.51
4.9
4.1
—
—
—
0
0
18
135
1.33
0.51
1.3
1.9
—
—
—
0
0
18
135
1.33
0.51
1.1
1.1
—
—
—
0
0
26
206
1.26
0.50
2.8
3.3
—
—
—
0
0
96
857
1.12
0.50
4.6
3.8
60.13
58.06
%
0.77
96
857
14
101
1.39
0.49
1.8
1.8
1.47
2.20
ug/l
—
9
54
7
46
1.52
0.48
1.3
1.3
—
—
—
0
0
91
813
1.12
0.48
1.4
1.4
60.33
62.10
mmol/l
0.18
64
655
80
709
1.13
0.48
1.1
1.2
—
—
—
0
0
24
190
1.26
0.47
1.3
4.2
81.40
62.42
mg/l
0.69
15
142
13
94
1.38
0.46
1.2
1.3
—
—
—
0
0
22
276
0.80
0.45
1.9
2.1
524.12
496.54
min
0.77
17
196
44
375
1.17
0.45
5.2
2.3
—
—
—
0
0
36
302
1.19
0.44
1.9
1.4
1.00
1.17
promille
0.26
29
240
19
148
1.28
0.43
1.2
1.8
1772.38
19721.55
e6/l
—
8
83
152
1643
0.92
0.43
1.9
2.0
21.58
21.66
s
0.05
134
1448
5
31
1.61
0.43
1.0
1.0
—
—
—
0
0
5
31
1.61
0.43
1.2
1.8
3.72
4.95
nmol/l
—
5
31
244
2590
0.94
0.42
1.4
1.3
—
—
—
0
0
20
251
0.80
0.42
1.3
1.3
—
—
—
0
0
110
1003
1.10
0.42
1.3
1.2
—
—
—
0
0
36
304
1.19
0.41
1.2
2.3
7.40
6.71
mmol/l
0.51
23
208
5
33
1.52
0.41
1.2
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
263.38
—
0
16
1618
15881
1.03
0.40
4.3
3.8
91.59
116.32
e6/l
0.61
1145
11305
27
223
1.21
0.39
2.8
1.8
10.20
9.66
mmol/l
0.48
27
218
62
550
1.13
0.39
1.5
1.4
26.71
60.80
mu/l
2.60
54
490
14
106
1.32
0.39
1.4
1.8
—
—
—
0
0
1281
13086
0.97
0.39
3.3
3.0
—
—
—
0
0
71
791
0.90
0.38
4.0
2.7
67.35
62.75
%
1.13
71
786
528
5090
1.04
0.38
3.5
4.0
22.02
31.13
ug/l
0.41
420
4172
56
495
1.13
0.38
3.3
3.3
—
—
—
0
0
219
2321
0.94
0.38
5.4
4.1
24.17
24.17
mmol/l
0.01
213
2266
28
234
1.20
0.37
1.0
1.0
—
—
—
0
0
14
107
1.31
0.37
1.8
1.7
—
—
—
0
0
245
2584
0.95
0.36
8.4
8.6
24.34
24.30
mmol/l
0.09
227
2486
61
682
0.89
0.36
1.5
1.6
—
—
—
0
0
1922
18931
1.02
0.36
10.5
9.9
0.00
0.00
e9/l
0.11
1577
15362
11
81
1.36
0.36
1.7
3.7
—
—
—
0
0
11
81
1.36
0.36
1.3
1.1
—
—
—
0
0
14
108
1.30
0.35
1.1
1.5
—
—
—
0
0
33
282
1.17
0.35
1.4
1.3
—
—
—
0
0
17
135
1.26
0.35
1.2
1.3
716.70
347.04
ug/l
—
9
67
6
43
1.40
0.35
1.3
2.1
—
—
—
0
0
52
461
1.13
0.34
1.4
1.3
282.76
278.36
mosm/kgh2o
0.58
38
351
84
766
1.10
0.34
1.3
1.2
24.85
46.06
u/ml
1.14
14
83
92
1002
0.92
0.34
1.2
1.2
—
—
—
0
0
20
243
0.82
0.33
1.1
1.1
—
—
—
0
0
10
74
1.35
0.32
6.5
6.8
—
—
—
0
0
28
327
0.86
0.31
1.0
1.0
—
—
—
0
0
43
380
1.13
0.31
1.8
2.2
600.44
648.21
ml
0.33
25
240
33
286
1.15
0.31
1.6
1.6
90.55
82.76
umol/l
0.46
33
286
19
156
1.22
0.31
1.5
1.2
—
—
—
0
0
7
54
1.30
0.30
2.1
2.5
1.14
0.52
u/field
—
7
54
10
75
1.33
0.30
2.1
1.5
162.52
139.17
ng/l
—
10
75
39
345
1.13
0.28
4.8
5.0
431.49
110.19
u/ml
—
10
93
11
85
1.29
0.28
2.1
1.9
—
—
—
0
0
389
4021
0.96
0.27
8.7
7.9
—
—
—
0
0
9
119
0.76
0.27
1.1
1.1
—
—
—
0
0
29
252
1.15
0.27
1.0
1.1
—
—
—
0
0
5
74
0.68
0.26
1.6
1.2
—
—
—
0
0
11
138
0.80
0.25
1.1
1.2
—
—
—
0
0
311
3004
1.04
0.24
8.1
8.5
1.33
1.33
%
0.01
311
2982
11
137
0.80
0.24
1.0
1.1
—
—
—
0
0
5
41
1.22
0.22
1.2
1.0
—
—
—
0
0
17
144
1.18
0.22
1.1
1.1
1196.59
1642.97
miu/ml
1.38
17
144
5
42
1.19
0.21
3.0
1.2
97.98
143.31
mmol/l
—
5
35
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
43
471
0.91
0.21
3.3
3.7
83.71
45.87
u/ml
0.33
43
466
106
1004
1.06
0.20
4.8
4.5
2.52
2.67
mmol/l
0.17
59
712
0
14
0.00
0.20
0.0
1.1
—
5.86
—
0
9
0
14
0.00
0.20
0.0
4.4
—
1.40
—
0
14
13
108
1.20
0.20
1.0
1.1
—
—
—
0
0
13
108
1.20
0.20
1.0
1.1
—
—
—
0
0
13
108
1.20
0.20
1.0
1.1
—
—
—
0
0
18
155
1.16
0.19
1.1
1.1
47.38
530.95
ng/l
—
5
41
43
396
1.09
0.18
1.2
1.5
—
—
—
0
0
57
610
0.93
0.17
1.2
1.2
2.42
3.86
u/ml
1.77
19
255
150
1442
1.04
0.17
3.3
3.3
—
—
—
0
0
20
226
0.88
0.17
1.0
1.2
1.00
1.06
ratio
—
5
75
7
63
1.11
0.17
1.0
1.0
—
—
—
0
0
110
1151
0.95
0.17
2.2
2.2
157.01
101.47
ug/min
0.51
61
680
65
690
0.94
0.16
3.4
2.0
—
—
—
0
0
55
515
1.07
0.16
1.3
1.3
234.66
290.16
pmol/l
0.96
50
441
27
245
1.10
0.15
1.2
1.3
—
—
—
0
0
84
882
0.95
0.15
1.7
1.7
44.87
42.52
nmol/l
0.40
77
851
249
2426
1.03
0.15
1.2
1.2
158.86
139.83
iu/ml
0.33
96
875
306
2991
1.02
0.14
8.2
8.6
0.68
0.67
%
0.31
306
2966
17
150
1.13
0.14
1.2
1.1
—
0.16
—
0
10
79
827
0.95
0.13
1.7
1.5
—
—
—
0
0
25
228
1.10
0.13
1.6
1.4
148.19
205.77
pmol/l
0.66
25
228
9
106
0.85
0.13
1.7
1.5
—
—
—
0
0
23
252
0.91
0.12
2.0
2.0
—
—
—
0
0
15
169
0.89
0.12
1.1
1.1
—
6.56
u/ml
—
0
16
28
258
1.09
0.12
1.5
1.9
—
—
—
0
0
108
1119
0.96
0.12
4.8
3.6
1.57
1.62
mg/l
0.32
99
1021
44
466
0.94
0.11
1.1
1.3
8.13
7.53
mmol/l
0.51
35
401
57
543
1.05
0.11
1.1
1.1
1.51
1.52
g/l
0.13
52
495
66
632
1.04
0.10
1.4
1.5
1472.85
2078.41
e6/l
0.75
48
451
32
299
1.07
0.10
1.1
1.1
—
—
—
0
0
100
968
1.03
0.10
1.7
1.7
3.39
4.51
iu/l
0.95
34
322
56
535
1.05
0.10
1.5
1.3
—
—
—
0
0
158
1542
1.03
0.10
2.1
2.1
37.48
37.21
g/l
0.23
125
1340
1226
12343
0.99
0.09
3.5
3.2
—
—
—
0
0
32
340
0.94
0.09
1.3
1.5
—
—
—
0
0
32
301
1.06
0.09
1.2
1.2
35.20
34.64
mmol/l
0.06
27
255
98
951
1.03
0.09
2.2
2.7
33.26
34.94
umol/l
0.31
84
853
6
57
1.05
0.08
1.0
1.1
—
—
—
0
0
27
253
1.07
0.08
1.4
1.7
—
—
—
0
0
5
64
0.78
0.08
5.0
3.3
33.60
40.79
umol/l
—
5
54
95
977
0.97
0.08
3.9
3.1
—
—
—
0
0
124
1211
1.02
0.08
2.5
2.6
—
—
—
0
0
135
1320
1.02
0.08
1.4
1.4
277.26
266.51
ug/g
0.24
74
815
26
244
1.07
0.08
6.4
6.3
—
—
—
0
0
43
411
1.05
0.08
1.1
1.1
—
—
—
0
0
104
1015
1.03
0.07
2.3
3.4
426.03
694.59
u/ml
0.32
95
934
48
499
0.96
0.07
1.4
1.5
—
—
—
0
0
42
438
0.96
0.07
1.3
1.2
—
—
—
0
0
412
4162
0.99
0.07
6.8
6.6
1.32
1.35
mmol/l
0.32
401
4048
8
95
0.84
0.06
1.0
1.4
—
—
—
0
0
60
581
1.03
0.06
1.3
1.4
22625.10
53547.77
e6/l
1.50
31
344
218
2150
1.01
0.06
2.9
4.0
78.61
65.11
u/ml
0.20
206
2067
15
162
0.93
0.06
4.5
3.2
53.20
53.52
%
0.02
15
157
111
1088
1.02
0.06
1.3
1.2
—
—
—
0
0
54
557
0.97
0.05
1.3
1.5
—
—
—
0
0
746
7416
1.01
0.05
3.4
3.0
2.53
2.44
e6/l
0.10
415
4042
74
758
0.98
0.05
1.7
1.2
62.70
41.72
u/l
0.50
64
663
63
647
0.97
0.05
1.1
1.1
—
—
—
0
0
16
149
1.07
0.05
2.1
1.9
—
—
—
0
0
45
465
0.97
0.05
1.1
1.1
2.81
2.93
u/ml
0.03
18
182
103
1049
0.98
0.05
1.1
1.2
—
—
—
0
0
32
332
0.96
0.04
1.4
1.4
—
—
—
0
0
90
884
1.02
0.04
3.7
3.0
—
—
—
0
0
1269
12730
1.00
0.04
3.7
3.3
0.37
0.47
e6/l
0.97
967
9699
36
348
1.03
0.04
2.8
2.6
10.71
10.95
%
0.14
36
348
39
378
1.03
0.04
1.9
2.1
3.00
1.78
u/field
0.55
22
142
35
339
1.03
0.03
1.3
1.4
12.51
13.11
u/l
0.28
35
327
60
588
1.02
0.03
2.8
2.1
32.45
32.78
pg
0.20
60
581
32
330
0.97
0.03
1.3
1.4
—
—
—
0
0
21
201
1.04
0.03
1.2
1.2
—
—
—
0
0
10
108
0.93
0.03
1.2
1.1
—
—
—
0
0
22
211
1.04
0.03
1.2
1.1
—
—
—
0
0
12
112
1.07
0.03
1.1
1.2
291.50
305.63
pmol/l
—
6
81
54
530
1.02
0.02
1.9
1.6
—
—
—
0
0
18
172
1.05
0.02
1.1
1.2
149.67
155.00
mmol/24h
0.14
18
172
1157
11549
1.00
0.02
4.1
4.1
87.59
87.61
%
0.01
1122
11275
72
711
1.01
0.01
1.4
1.5
31.10
31.91
g/l
0.20
66
636
63
622
1.01
0.01
1.1
1.1
27.75
1258.83
iu/ml
0.73
17
140
118
1188
0.99
0.01
4.8
4.3
7.42
7.42
ph
0.37
106
1066
65
657
0.99
0.01
1.1
1.1
—
—
—
0
0
103
1023
1.01
0.00
4.6
3.9
—
—
—
0
0
19
196
0.97
0.00
1.0
1.0
—
—
—
0
0
11
112
0.98
0.00
2.1
1.5
—
—
—
0
0
15
152
0.99
0.00
1.6
2.7
137.56
144.03
umol/l
—
9
88
55
552
1.00
0.00
1.3
1.6
—
—
—
0
0
47
475
0.99
0.00
1.3
1.4
6.35
6.41
mmol/l
0.06
47
440
17
166
1.02
0.00
2.6
1.9
24.32
226.74
ug/l
0.64
17
155
1387
13866
1.00
0.00
3.8
3.3
132.54
74.08
e6/l
0.31
1054
10634
31
311
1.00
0.00
1.3
1.3
—
—
—
0
0
97
971
1.00
0.00
2.8
2.5
16.47
16.00
%
0.71
51
523
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
5
57
0.88
0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
0.00
1.6
1.8
—
—
—
0
0
5
51
0.98
-0.00
1.4
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
13
130
1.00
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
1650.73
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
-0.00
2.0
1.4
66.44
74.76
%
—
5
46
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.0
2.9
1.02
1.02
mmol/l
—
5
35
0
6
0.00
-0.00
0.0
1.0
—
1.98
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1778.00
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H8_HL_MIX_NAS and mortality.

Females

Parameter HR [95% CI] p-value
H8_HL_MIX_NAS 0.993 [0.92, 1.07] 0.846
Birth year 0.994 [0.99, 1.0] 0.124

During the follow-up period (1.1.1998 — 31.12.2019), 4413 out of 18401 females with H8_HL_MIX_NAS died.

Males

Parameter HR [95% CI] p-value
H8_HL_MIX_NAS 0.992 [0.91, 1.08] 0.842
Birth year 0.987 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 4113 out of 15201 males with H8_HL_MIX_NAS died.

Mortality risk

Mortality risk for people of age

years, who have H8_HL_MIX_NAS.

N-year risk Females Males
1 0.082% 0.181%
5 0.554% 1.226%
10 1.44% 3.036%
15 2.885% 5.615%
20 4.912% 9.624%

Relationships between endpoints

Index endpoint: H8_HL_MIX_NAS – Mixed conductive and sensorineural hearing loss

GWS hits: 4

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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