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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Right side

Z21_RIGHT_SIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 ZB0.1
  • Cause of death: ICD-10 ZB0.1

2 out of 7 registries used, show all original rules.

190

4. Check minimum number of events

None

190

5. Include endpoints

None

190

6. Filter based on genotype QC (FinnGen only)

190

Control definitions (FinnGen only)

Control exclude
Z21_ADDIT_CODES_LOCAT_DEFECT_INJURY_ILLNE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Z[AB]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 190 100 90
Unadjusted period prevalence (%) 0.04 0.03 0.04
Median age at first event (years) 71.25 72.05 70.36

-FinnGen-

Age distribution of first events

0102050607080010203040506070AgeIndividuals

-FinnGen-

Year distribution of first events

19701975198019851990199520002005202020230102030405060708090100110YearIndividuals

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
184
Matched controls
1839
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
ZB0.1
ICD-10 Finland
Right side
+∞
260.0
182
*
M17.1
ICD-10 Finland
Other primary gonarthrosis
9.5
42.7
120
302
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
10.0
29.7
65
95
Z50.1
ICD-10 Finland
Other physical therapy
13.2
28.4
52
53
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
10.6
28.3
59
78
SPAT1212
SPAT
Extensive examination of musculoskeletal system
9.2
25.9
59
90
M16.1
ICD-10 Finland
Other primary coxarthrosis
6.6
24.9
75
173
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
8.5
23.6
56
90
B01AB10
ATC
tinzaparin; parenteral
9.9
23.5
50
67
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
11.0
19.9
39
44
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
5.8
18.9
60
141
ZB0.0
ICD-10 Finland
Left side
+∞
18.0
17
*
M01AH05
ATC
etoricoxib; oral
4.4
17.7
144
828
R4135
NOMESCO Finland
Rehabilitation for hearing problems
17.7
14.3
22
14
A10BA02
ATC
metformin; oral
3.4
13.3
88
389
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.4
12.7
81
347
B01AF01
ATC
rivaroxaban; oral
4.1
11.4
49
151
103
Kela drug reimbursment
Diabetes, insulin-treated
3.0
10.8
81
377
D82
ICPC
Teeth/gum disease
0.2
10.0
9
425
M76.4
ICD-10 Finland
Tibial collateral bursitis [Pellegrini-Stieda]
16.2
9.7
15
10
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.4
8.4
43
151
N02BE01
ATC
paracetamol; systemic, rectal
4.6
8.4
173
1422
WX320
NOMESCO Finland
Spinalanesthesy
0.1
8.4
5
313
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.0
8.2
54
223
WX002
NOMESCO Finland
Sedation and analgesia
0.1
8.1
*
289
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
3.4
8.1
41
143
B01AB05
ATC
enoxaparin; parenteral
2.5
7.7
82
451
WX408
NOMESCO Finland
General anesthesy, balanced
0.2
7.6
9
368
SPAT1324
SPAT
Screening procedure
3.7
7.5
33
102
SPAT1059
SPAT
Spirometry at the office
4.9
7.5
24
55
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.9
7.4
50
209
GD1AA
NOMESCO Finland
Thorax X-ray examination
0.4
7.0
36
716
Z46.9
ICD-10 Finland
Fitting and adjustment of unspecified device
17.5
6.8
10
6
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
0.4
6.6
31
640
WX404
NOMESCO Finland
Intravenous generell anesthesy
0.1
6.5
*
253
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.4
6.2
63
330
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.3
6.1
76
437
A10BH01
ATC
sitagliptin; oral
3.2
6.1
33
118
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
3.4
6.0
28
91
SPAT1262
SPAT
Handing over of treatment supplies
2.5
6.0
53
259

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
143
61
91.73
220.90
4.9
5.6
—
—
—
0
0
149
101
64.73
190.41
5.1
4.4
—
—
—
0
0
59
31
27.15
78.62
2.5
3.3
105.95
106.23
mmol/l
0.12
59
31
59
31
27.15
78.62
2.5
3.3
4.07
3.95
mmol/l
0.96
59
31
59
31
27.15
78.62
2.5
3.3
—
—
—
0
0
179
566
38.35
68.59
7.4
4.4
—
—
—
0
0
162
465
17.85
66.71
5.8
3.8
—
—
—
0
0
69
74
14.07
62.08
3.0
4.9
0.70
0.87
%
2.76
69
69
69
74
14.07
62.08
3.0
4.8
1.50
1.59
%
0.27
69
68
95
161
10.80
60.66
4.0
2.9
4.24
4.31
kpa
0.14
95
154
139
368
11.35
59.74
3.6
3.1
669.98
553.04
mosm/kgh2o
5.50
133
315
95
190
9.00
51.50
4.0
3.7
5.55
5.70
kpa
0.81
95
185
95
190
9.00
51.50
4.0
3.7
1.98
1.99
mmol/l
0.01
77
153
95
195
8.74
50.12
4.0
3.7
—
—
—
0
0
45
49
11.72
39.06
5.4
4.8
21.34
33.27
mg/l
1.51
39
32
143
545
7.56
37.61
6.5
3.4
—
—
—
0
0
170
789
11.97
35.51
5.4
4.2
—
—
—
0
0
7
848
0.05
34.56
3.1
6.0
1.22
1.21
mmol/l
—
7
773
59
112
7.19
32.05
2.5
2.6
1.08
1.16
%
0.19
59
112
62
133
6.44
29.63
3.5
4.3
0.40
0.15
%
—
10
40
62
149
5.69
25.94
3.5
4.1
1.20
0.98
%
—
10
48
131
579
5.07
25.51
4.0
3.4
—
—
—
0
0
122
515
4.82
25.12
2.3
3.2
0.10
0.55
e6/l
4.24
115
376
126
564
4.66
23.51
2.6
3.4
25.09
52.99
e6/l
1.08
118
430
53
127
5.40
21.95
3.3
4.3
1.50
0.44
%
—
6
32
53
127
5.40
21.95
3.5
4.5
0.17
0.03
%
—
6
37
98
399
4.01
20.06
1.2
1.3
—
—
—
0
0
129
645
4.11
19.29
2.9
4.0
102.40
73.28
e6/l
0.25
123
462
166
1040
5.72
17.11
5.2
4.8
7.10
6.88
mmol/l
0.65
156
979
185
1415
12.67
16.02
19.8
17.3
10.67
39.31
%
26.19
92
927
86
366
3.47
15.65
5.0
4.9
—
—
—
0
0
70
262
3.65
15.56
2.9
6.3
105.54
103.35
mmol/l
3.66
70
255
53
164
4.10
15.53
3.1
4.3
1.24
1.23
mmol/l
1.36
48
148
113
593
3.23
14.12
5.2
4.1
5.14
8.40
mg/mmol
0.55
106
377
43
122
4.26
14.07
7.2
2.4
—
—
—
0
0
60
1127
0.32
12.48
6.0
4.8
—
304.27
—
0
26
85
404
3.00
12.21
1.7
1.8
383.88
451.12
pmol/l
1.70
73
325
101
558
2.73
10.52
1.8
2.5
—
—
—
0
0
160
1148
3.49
9.76
5.9
4.6
—
—
—
0
0
32
100
3.65
8.97
2.6
2.5
—
—
—
0
0
167
1265
3.64
8.57
4.5
4.3
11.38
13.97
mm/h
1.78
156
1146
190
1711
+∞
7.91
19.6
19.7
140.15
139.66
mmol/l
2.54
190
1665
10
444
0.18
7.87
7.6
3.8
87.80
88.54
%
—
10
434
190
1715
+∞
7.69
19.2
19.8
4.05
3.99
mmol/l
2.41
190
1669
190
1721
+∞
7.51
22.9
20.2
82.55
80.34
umol/l
0.59
190
1721
11
439
0.20
7.28
1.5
7.0
—
—
—
0
0
11
16
7.24
7.23
1.3
1.4
—
—
—
0
0
0
163
0.00
6.68
0.0
3.5
—
—
—
0
0
0
163
0.00
6.68
0.0
4.2
—
—
—
0
0
112
769
2.11
5.89
5.1
5.9
2.76
2.71
%
0.09
107
717
115
800
2.11
5.81
2.7
4.5
38.10
34.91
g/l
7.01
115
754
36
691
0.41
5.64
1.9
2.2
—
—
—
0
0
12
383
0.27
5.27
3.3
2.7
6.63
4.86
e6/l
0.51
12
338
190
1775
+∞
5.14
28.3
24.2
4.44
4.44
e12/l
0.04
190
1716
190
1775
+∞
5.14
28.8
24.3
134.16
134.54
g/l
0.13
190
1741
190
1775
+∞
5.14
28.5
24.2
7.06
6.74
e9/l
1.06
190
1718
190
1775
+∞
5.14
28.3
24.1
90.74
91.67
fl
2.35
190
1744
190
1774
+∞
5.13
28.2
24.1
30.24
30.47
pg
1.03
190
1743
190
1774
+∞
5.13
28.3
24.2
251.42
244.38
e9/l
0.96
190
1723
21
492
0.36
5.05
2.8
3.1
—
—
—
0
0
107
759
1.94
4.75
5.2
4.0
20.15
38.61
ng/l
2.39
92
576
182
1632
3.73
4.59
7.1
5.1
6.81
6.11
mmol/l
6.89
182
1469
106
760
1.89
4.45
1.9
2.0
93.89
95.12
pmol/l
0.14
75
380
9
12
7.81
4.40
2.2
2.7
—
—
—
0
0
6
227
0.24
4.28
1.2
1.2
—
—
—
0
0
12
344
0.30
4.24
1.7
3.8
20.17
218.07
ng/l
—
6
292
31
572
0.45
4.05
2.2
5.7
—
—
—
0
0
0
100
0.00
3.98
0.0
3.4
—
24.43
—
0
92
0
102
0.00
3.95
0.0
1.2
—
—
—
0
0
7
230
0.28
3.79
1.3
1.3
—
—
—
0
0
23
100
2.48
3.60
1.1
1.3
—
—
—
0
0
5
186
0.25
3.49
1.2
6.4
1.68
1.40
mmol/l
—
5
177
5
184
0.25
3.33
1.2
1.5
—
—
—
0
0
0
83
0.00
3.22
0.0
4.1
—
—
—
0
0
58
378
1.77
3.09
2.4
1.8
0.98
1.36
mg/l
1.11
53
312
22
105
2.24
2.82
1.1
1.3
—
—
—
0
0
8
19
4.35
2.71
1.1
2.7
—
—
—
0
0
23
417
0.49
2.68
8.6
3.8
—
—
—
0
0
0
68
0.00
2.66
0.0
2.0
—
—
—
0
0
0
67
0.00
2.44
0.0
3.6
—
3.90
—
0
61
9
211
0.40
2.38
1.2
1.3
—
—
—
0
0
97
761
1.56
2.38
11.6
9.8
1.37
1.26
inr
0.34
16
214
0
62
0.00
2.27
0.0
9.6
—
—
—
0
0
12
51
2.44
1.99
2.0
1.6
—
—
—
0
0
5
139
0.34
1.98
2.2
2.7
46.80
182.93
ng/l
—
5
123
73
556
1.51
1.96
2.8
3.2
30.25
167.64
mg/l
0.64
39
362
5
11
4.64
1.95
1.2
1.0
—
—
—
0
0
5
11
4.64
1.95
1.4
2.4
12.79
14.28
umol/l
—
5
11
14
68
2.14
1.75
1.1
1.3
—
—
—
0
0
6
149
0.38
1.72
1.7
1.5
—
—
—
0
0
10
42
2.46
1.70
1.2
3.2
—
—
—
0
0
0
44
0.00
1.53
0.0
1.2
—
—
—
0
0
0
44
0.00
1.53
0.0
2.1
—
—
—
0
0
6
21
2.92
1.52
1.2
1.4
—
—
—
0
0
9
40
2.31
1.42
1.7
2.3
—
—
—
0
0
7
150
0.45
1.38
1.0
1.5
—
—
—
0
0
0
38
0.00
1.36
0.0
1.8
—
60.67
—
0
38
0
39
0.00
1.35
0.0
2.5
—
—
—
0
0
0
39
0.00
1.35
0.0
1.2
—
—
—
0
0
6
24
2.55
1.31
1.2
1.4
0.72
0.48
nmol/l
—
6
19
39
282
1.48
1.31
2.7
1.8
—
—
—
0
0
39
282
1.48
1.31
2.7
2.4
2.51
2.29
g/l
2.05
39
257
8
151
0.51
1.20
1.0
1.4
—
—
—
0
0
0
33
0.00
1.17
0.0
1.2
—
—
—
0
0
0
33
0.00
1.17
0.0
2.3
—
5.16
—
0
33
0
33
0.00
1.17
0.0
2.8
—
63.00
—
0
33
29
202
1.51
1.16
1.3
1.7
—
—
—
0
0
7
139
0.48
1.14
1.7
1.4
—
—
—
0
0
27
375
0.67
1.09
2.4
3.0
0.98
0.75
ug/l
1.42
20
264
146
1342
1.38
1.07
7.0
8.0
83.91
81.29
u/l
0.32
141
1247
5
23
2.20
0.98
1.2
1.4
—
—
—
0
0
0
29
0.00
0.98
0.0
1.1
—
—
—
0
0
0
30
0.00
0.98
0.0
1.8
—
88.96
—
0
30
0
31
0.00
0.97
0.0
1.4
—
—
—
0
0
0
32
0.00
0.96
0.0
3.1
—
—
—
0
0
7
37
1.93
0.95
1.1
1.2
—
—
—
0
0
29
214
1.42
0.89
2.7
4.8
27.82
26.77
ug/l
0.01
24
185
13
80
1.67
0.87
1.3
1.1
200.00
137.50
iu/ml
—
6
30
39
306
1.35
0.84
3.1
2.4
13.34
12.43
umol/l
0.36
39
280
8
47
1.73
0.81
1.0
5.0
—
—
—
0
0
0
24
0.00
0.79
0.0
1.4
—
—
—
0
0
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
278.18
—
0
17
0
24
0.00
0.79
0.0
4.6
—
—
—
0
0
0
25
0.00
0.79
0.0
1.6
—
—
—
0
0
0
25
0.00
0.79
0.0
1.6
—
—
—
0
0
0
25
0.00
0.79
0.0
1.6
—
—
—
0
0
0
25
0.00
0.79
0.0
1.6
—
—
—
0
0
0
27
0.00
0.78
0.0
1.5
—
—
—
0
0
0
28
0.00
0.76
0.0
9.6
—
6.33
—
0
22
11
167
0.64
0.69
2.1
7.9
—
—
—
0
0
17
233
0.70
0.66
1.1
1.4
—
—
—
0
0
34
273
1.30
0.64
2.7
2.4
23.68
21.15
%
0.53
34
241
104
948
1.21
0.64
5.8
6.7
9.62
11.55
umol/l
2.52
98
896
9
141
0.62
0.63
1.4
2.1
12.92
10.41
g/l
—
9
124
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
2.8
—
3.48
—
0
21
0
21
0.00
0.60
0.0
2.9
—
—
—
0
0
21
158
1.37
0.60
2.6
2.0
381.57
388.70
nmol/l
0.07
21
148
6
40
1.52
0.52
1.8
2.8
—
—
—
0
0
157
1505
1.25
0.51
5.1
4.8
2.09
2.01
mu/l
0.32
157
1337
8
117
0.67
0.47
1.0
1.8
0.91
1.47
g/l
—
8
105
63
561
1.18
0.47
2.8
3.2
7.25
7.30
mmol/l
0.03
50
454
13
94
1.41
0.47
3.2
3.2
70.08
1731.61
u/ml
0.56
13
77
28
338
0.80
0.47
1.1
1.2
0.76
0.87
u/ml
0.21
14
101
5
32
1.58
0.42
1.6
1.1
16.77
9.87
u/l
—
5
25
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.8
—
12.12
—
0
16
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
30
252
1.23
0.41
1.4
1.3
0.99
14.23
u/ml
1.63
22
88
0
17
0.00
0.41
0.0
2.3
—
—
—
0
0
32
271
1.22
0.41
1.3
1.3
22.00
46.56
iu/ml
—
10
94
0
18
0.00
0.40
0.0
2.8
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
527.63
—
0
8
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
15
116
1.32
0.38
4.3
1.9
6.66
13.90
nmol/l
3.78
15
104
9
71
1.28
0.36
1.0
1.2
—
—
—
0
0
14
174
0.79
0.31
1.0
1.5
—
—
—
0
0
8
65
1.24
0.27
1.0
4.1
32.55
33.95
mg/l
—
8
49
8
65
1.24
0.27
1.0
4.1
45.05
171.10
mg/l
—
8
49
5
75
0.66
0.26
1.0
1.9
55.60
388.02
ug/l
—
5
68
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
26.38
—
0
10
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
1.89
—
0
14
34
372
0.90
0.19
1.2
1.7
685.26
1214.54
nmol/l
5.45
34
279
49
525
0.91
0.19
4.2
4.4
—
—
—
0
0
13
111
1.18
0.16
1.2
1.3
—
36.25
—
0
10
6
79
0.75
0.16
1.0
1.3
—
—
—
0
0
54
562
0.95
0.10
1.9
2.1
160.88
181.33
u/l
0.25
49
529
5
46
1.09
0.09
1.0
1.3
—
—
—
0
0
14
151
0.92
0.05
2.9
7.3
9.56
9.87
mmol/l
0.09
14
143
120
1215
0.97
0.05
3.7
4.4
—
—
—
0
0
39
378
1.04
0.04
6.5
4.4
1.01
1.02
kg/l
0.54
26
45
15
141
1.07
0.03
1.9
1.5
—
—
—
0
0
14
144
0.97
0.00
1.4
2.1
—
—
—
0
0
24
238
1.01
0.00
3.5
5.7
1.02
1.03
mmol/l
0.06
24
223
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
9
92
0.98
0.00
1.3
2.6
0.97
1.62
g/l
—
9
83
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
2.70
—
0
5
0
6
0.00
0.00
0.0
1.7
—
1.78
—
0
6
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
41.67
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.9
—
0.78
—
0
7
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
0.66
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: Z21_RIGHT_SIDE – Right side

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).