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Scleritis and episcleritis

H7_SCLERITISEPISCLERITIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

2379

6. Filter based on genotype QC (FinnGen only)

2379

Control definitions (FinnGen only)

Control exclude
H7_SCLERACORNEA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 2379 1644 735
Unadjusted period prevalence (%) 0.49 0.56 0.32
Median age at first event (years) 49.38 48.30 51.79

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2102
Matched controls
21019
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H15.0
ICD-10 Finland
Scleritis
4841.0
323.0
406
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
784.9
323.0
486
8
H15.1
ICD-10 Finland
Episcleritis
7091.9
323.0
1802
16
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
5.5
274.8
1164
3886
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.5
155.4
1139
5325
H57.1
ICD-10 Finland
Ocular pain
13.3
149.9
273
233
H04.10
ICD-10 Finland
Dry eye syndrome
5.7
139.0
450
964
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
10.9
121.6
243
248
H16.0
ICD-10 Finland
Corneal ulcer
21.0
118.0
178
92
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
173.6
110.5
115
7
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
21.7
105.2
157
78
H20.1
ICD-10 Finland
Chronic iridocyclitis
+∞
99.8
95
*
S01BC03
ATC
diclofenac; ophthalmic
12.4
92.4
172
150
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.5
89.6
503
1752
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.7
78.5
387
1203
H02AB06
ATC
prednisolone; systemic
2.3
70.5
1114
6949
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
4.7
67.4
247
578
H16.9
ICD-10 Finland
Keratitis, unspecified
108.0
67.3
73
7
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
3.5
61.5
317
1007
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
4.8
58.7
211
482
S01FA04
ATC
cyclopentolate; ophthalmic
37.0
58.6
75
21
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
28.9
57.4
78
28
A07EC01
ATC
sulfasalazine; oral, rectal
3.6
55.4
276
849
F01
ICPC
Eye pain
7.5
55.0
135
191
F02
ICPC
Red eye
5.5
54.0
169
330
S01AD03
ATC
aciclovir; ophthalmic
6.6
53.3
143
230
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.3
50.3
274
901
M45
ICD-10 Finland
Ankylosing spondylitis
8.9
49.4
108
127
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
467.7
46.5
46
*
A02BC02
ATC
pantoprazole; systemic
1.9
44.4
1380
10438
R51.80
ICD-10 Finland
Headache
2.4
40.4
393
1835
L04AX01
ATC
azathioprine; systemic
4.2
39.7
158
397
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.2
37.5
212
711
H20
ICD-10 Finland
Iridocyclitis
62.6
37.2
43
7
H02AB07
ATC
prednisone; oral
2.4
36.0
347
1605
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
5.0
32.4
107
222
H20.8
ICD-10 Finland
Other iridocyclitis
162.4
30.7
32
*
H16.2
ICD-10 Finland
Keratoconjunctivitis
157.2
29.7
31
*
S01BC05
ATC
ketorolac; ophthalmic
4.9
29.1
98
208
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
3.1
29.1
168
570
S01ED01
ATC
timolol; ophthalmic
5.6
29.0
86
158
H11.3
ICD-10 Finland
Conjunctival haemorrhage
4.2
28.8
113
280
N02BE01
ATC
paracetamol; systemic, rectal
1.9
28.5
1772
15470
M25.5
ICD-10 Finland
Pain in joint
1.8
28.0
646
4186
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
4.7
27.9
97
213
F29
ICPC
Eye symptom/complaint other
2.7
27.3
202
802
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
3.7
26.9
120
334
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
26.7
629
4095
J01AA02
ATC
doxycycline; systemic
1.8
26.4
1622
13844
S01GX01
ATC
cromoglicic acid; ophthalmic
1.9
26.1
473
2817
L04AB04
ATC
adalimumab; parenteral
5.6
26.1
77
141
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.7
25.6
182
706
S01FA02
ATC
scopolamine; ophthalmic
12.7
25.4
45
36
N02AX02
ATC
tramadol; systemic, rectal
1.7
24.9
841
6048
H10
ICD-10 Finland
Conjunctivitis
2.8
24.9
166
617
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.7
24.6
183
729
M01AH05
ATC
etoricoxib; oral
1.6
24.4
1248
9989
J01DB01
ATC
cefalexin; oral
1.8
24.3
1696
14785
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
24.2
744
5207
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
13.9
24.1
41
30
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
23.8
802
5741
M79.6
ICD-10 Finland
Pain in limb
1.7
23.7
736
5150
H01.0
ICD-10 Finland
Blepharitis
2.9
22.9
144
517
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.5
22.9
195
836
J01FA10
ATC
azithromycin; systemic
1.6
22.7
1256
10160
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
22.2
947
7169
M13.9
ICD-10 Finland
Arthritis, unspecified
2.6
22.0
172
704
A02BC03
ATC
lansoprazole; oral
1.7
21.8
580
3869
M01AE02
ATC
naproxen; oral, rectal
1.6
21.3
1190
9580
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
7.2
21.1
51
72
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
20.9
353
2031
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
4.3
20.9
79
190
M54.5
ICD-10 Finland
Low back pain
1.6
20.9
679
4772
M03BX02
ATC
tizanidine; oral
1.6
20.4
1313
10873
UJF32
NOMESCO Finland
Coloscopy
1.7
20.2
493
3193
P01BA02
ATC
hydroxychloroquine; oral
2.3
20.1
205
962
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
19.3
492
3224
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
18.9
499
3298
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
10.2
18.9
37
37
H40.0
ICD-10 Finland
Glaucoma suspect
2.6
18.8
148
606
S01ED51
ATC
timolol, combinations; ophthalmic
2.9
18.7
118
425
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.8
18.4
125
471
L88
ICPC
Rheumatoid/seropositive arthritis
3.2
18.4
98
315
R03AC02
ATC
salbutamol; inhalant
1.5
18.1
1068
8561
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
13.1
17.9
31
24
XCK00
NOMESCO Finland
Perimetry
2.6
17.8
136
549
R06.0
ICD-10 Finland
Dyspnoea
1.7
17.7
452
2954
J01FF01
ATC
clindamycin; systemic
1.6
17.7
540
3705
A02BC05
ATC
esomeprazole; systemic
1.5
17.5
809
6128
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
17.5
933
7298
J05AB01
ATC
aciclovir; systemic
1.7
17.3
426
2755
XCK10
NOMESCO Finland
Photography of fundus of eye
2.2
17.1
182
867
A02BC01
ATC
omeprazole; systemic
1.6
17.0
515
3520
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
4.8
16.9
56
119
J01FA09
ATC
clarithromycin; systemic
1.5
16.8
679
4979
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
63.8
16.7
19
*
K50.8
ICD-10 Finland
Other Crohn disease
4.8
16.7
56
120
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
2.7
16.6
118
458
H19.2*B02.3
ICD-10 Finland
Keratitis and keratoconjunctivitis (interstitial) in zoster
90.8
16.6
18
*
P01AB01
ATC
metronidazole; oral, rectal
1.5
16.5
820
6287
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
16.4
524
3627
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
16.3
333
2030
A07EC02
ATC
mesalazine; oral, rectal
2.5
15.9
130
544
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.6
15.7
120
486
H19.1
ICD-10 Finland
Herpesviral keratitis and keratoconjunctivitis
85.7
15.6
17
*
L04AB01
ATC
etanercept; parenteral
5.0
15.5
49
99
S01XA18
ATC
ciclosporin; ophthalmic
10.1
15.4
30
30
R01AD09
ATC
mometasone; nasal
1.5
15.1
935
7461
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.3
15.0
147
677
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
14.9
454
3095
M01AH01
ATC
celecoxib; oral (coxibs)
1.7
14.8
347
2201
J01MA02
ATC
ciprofloxacin; systemic
1.5
14.8
705
5326
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
5.6
14.7
42
76
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.2
14.5
156
749
G44.2
ICD-10 Finland
Tension-type headache
1.8
14.5
284
1709
L04AA13
ATC
leflunomide; oral
3.3
14.4
72
222
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
14.3
975
7898
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.0
14.2
186
968
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.9
14.1
231
1308
H16.1
ICD-10 Finland
Other superficial keratitis without conjunctivitis
42.8
14.1
17
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
13.9
717
5490
J01CA04
ATC
amoxicillin; systemic
1.5
13.8
1638
14739
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
13.8
407
2744
S01AX11
ATC
[U] ofloxacin; ophthalmic
3.2
13.8
71
225
J02AC01
ATC
fluconazole; systemic
1.4
13.8
868
6908
Z3229
NOMESCO Finland
Other healthcare associate professional
2.1
13.7
157
775
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.5
13.7
108
446
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.9
13.7
215
1200
ZXA00
NOMESCO Finland
Right side
1.6
13.7
463
3229
R42
ICD-10 Finland
Dizziness and giddiness
1.6
13.6
367
2412
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
4.6
13.6
47
105
UJF30
NOMESCO Finland
Ileoscopy through colon
1.9
13.6
193
1038
M01AC06
ATC
meloxicam; systemic, rectal
1.5
13.6
714
5480
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
13.5
355
2321
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
140.9
13.5
14
*
R06AX27
ATC
desloratadine; oral
1.5
13.3
576
4239
SPAT1009
SPAT
Measurement of intraocular pressure
5.6
13.3
38
69
R06AE07
ATC
cetirizine; oral
1.4
13.3
873
6990
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
10.5
13.2
25
24
R05
ICPC
Cough
1.6
12.8
421
2908
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.4
12.7
113
496
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
6.8
12.7
31
46
R52.9
ICD-10 Finland
Pain, unspecified
2.0
12.6
172
912
H53.1
ICD-10 Finland
Subjective visual disturbances
2.2
12.6
132
625
H18.8
ICD-10 Finland
Other specified disorders of cornea
32.2
12.6
16
5
R03DC03
ATC
montelukast; oral
1.6
12.6
330
2156
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
12.5
775
6115
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
12.5
186
1018
N03AX16
ATC
pregabalin; oral
1.5
12.5
436
3057
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
12.4
352
2341
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
12.4
485
3485
H25.1
ICD-10 Finland
Senile nuclear cataract
1.7
12.4
290
1832
J01FA06
ATC
roxithromycin; oral
1.4
12.4
796
6322
N03AX12
ATC
gabapentin; oral
1.7
12.4
290
1836
J05AB11
ATC
valaciclovir; oral
1.7
12.3
256
1566
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
37.8
12.2
15
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.9
12.2
178
966
H02AB04
ATC
methylprednisolone; systemic
1.7
12.1
274
1715
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
12.0
365
2468
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.6
12.0
53
150
A02BA02
ATC
ranitidine; systemic
1.6
11.9
338
2246
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.0
11.9
160
840
L04AB06
ATC
golimumab; parenteral
5.9
11.8
32
55
XCH00
NOMESCO Finland
Eye pressure measurement
2.8
11.8
74
269
L04AA06
ATC
mycophenolic acid; systemic
3.8
11.8
48
127
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
3.7
11.7
49
133
H26.2
ICD-10 Finland
Complicated cataract
5.3
11.5
34
65
H19.0*B02.3
ICD-10 Finland
Zoster scleritis
+∞
11.5
11
*
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
11.4
320
2121
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
11.4
691
5406
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
11.4
164
886
E0000UV
ATC
NA
1.4
11.4
745
5911
M01AB05
ATC
diclofenac; systemic, rectal
1.4
11.4
1330
11654
ZXA05
NOMESCO Finland
Left side
1.5
11.3
426
3029
H26.3
ICD-10 Finland
Drug-induced cataract
8.4
11.3
24
29
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
11.3
321
2133
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
3.2
11.3
58
185
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
11.3
619
4753
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
6.0
11.2
30
51
S01EC01
ATC
acetazolamide; systemic
3.9
11.1
44
114
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
2.7
11.1
74
280
114
Kela drug reimbursment
Glaucoma
2.2
11.0
114
537
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
11.0
1098
9339
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.6
11.0
80
316
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
10.9
317
2118
S18
ICPC
Laceration/cut
1.4
10.9
702
5544
R05
ICD-10 Finland
Cough
1.5
10.8
346
2371
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
10.8
563
4276
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
10.7
312
2085
K50.0
ICD-10 Finland
Crohn disease of small intestine
3.6
10.7
47
133
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
10.6
1282
11220
R20.2
ICD-10 Finland
Paraesthesia of skin
2.0
10.6
134
691
H10.4
ICD-10 Finland
Chronic conjunctivitis
6.0
10.6
28
47
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.4
10.5
1140
9796
R00.2
ICD-10 Finland
Palpitations
1.9
10.5
147
788
H16.8
ICD-10 Finland
Other keratitis
110.5
10.4
11
*
H19.0
ICD-10 Finland
Scleritis and episcleritis in diseases classified elsewhere
+∞
10.4
10
*
C07AB07
ATC
bisoprolol; oral
1.4
10.4
729
5828
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
10.4
993
8355
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
10.3
305
2048
R03BA05
ATC
fluticasone; inhalant
1.5
10.3
336
2307
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
10.3
1415
12619
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
10.3
188
1105
Z3231
NOMESCO Finland
Registered nurse
1.5
10.3
474
3511
ZXA10
NOMESCO Finland
Bilateral
1.6
10.2
308
2077
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
10.1
417
3014
D07AC01
ATC
betamethasone; topical
1.4
10.1
618
4818
J01MA12
ATC
levofloxacin; systemic
1.6
10.1
298
1997
F03
ICPC
Eye discharge
2.0
10.0
119
598
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.9
10.0
155
860
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.5
9.9
430
3137
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.7
9.9
211
1294
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.4
9.9
81
344
K02.1
ICD-10 Finland
Caries of dentine
1.3
9.9
1112
9572
S01FA01
ATC
atropine; ophthalmic
16.8
9.9
15
9
H19.3*M35.0
ICD-10 Finland
Keratoconjunctivitis sicca
20.1
9.8
14
7
R53
ICD-10 Finland
Malaise and fatigue
1.5
9.8
347
2426
S01GX09
ATC
olopatadine; ophthalmic
2.7
9.8
66
252
SPAT1263
SPAT
Sampling
1.4
9.7
769
6256
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
2.5
9.7
76
315
M79.1
ICD-10 Finland
Myalgia
1.6
9.7
245
1577
R50.9
ICD-10 Finland
Fever, unspecified
1.6
9.7
242
1555
H18.4
ICD-10 Finland
Corneal degeneration
55.2
9.6
11
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
9.6
163
935
K50.9
ICD-10 Finland
Crohn disease, unspecified
3.8
9.6
39
104
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
9.6
327
2269
R74
ICPC
Upper respiratory infection acute
1.4
9.6
560
4324
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.9
9.5
147
814
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
9.5
130
691
J20
ICD-10 Finland
Acute bronchitis
1.8
9.5
174
1019
L04AA01
ATC
[U] ciclosporin; systemic
4.1
9.5
36
90
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
15.1
9.5
15
10
-1
NOMESCO Finland
NA
1.4
9.5
642
5084
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.6
9.5
296
2009
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
17.6
9.4
14
8
H190, B005
ICD-10 Finland
NA
+∞
9.4
9
*
36903
ICD-8 Finland
Other inflammatory diseases of eye, Episcleritis
+∞
9.4
9
*
3790A
ICD-9 Finland
Other disorders of eye, Scleritis and episcleritis
+∞
9.4
9
*
G47.3
ICD-10 Finland
Sleep apnoea
1.5
9.3
377
2712
R51
ICD-10 Finland
Headache
2.1
9.3
109
545
S01EE01
ATC
latanoprost; ophthalmic
2.3
9.3
80
349
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.6
9.3
221
1401
G50.0
ICD-10 Finland
Trigeminal neuralgia
3.5
9.3
42
123
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.8
9.3
158
909
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
3.2
9.2
47
151
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
9.2
164
956
TAB00
NOMESCO Finland
Lumbar puncture
2.2
9.2
90
419
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
9.1
250
1646
S01GX08
ATC
ketotifen; ophthalmic
2.3
9.0
84
381
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
3.9
9.0
35
90
H10.2
ICD-10 Finland
Other acute conjunctivitis
3.9
9.0
35
90
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
9.0
506
3873
N06AX21
ATC
duloxetine; oral
1.6
8.9
210
1329
Z01.2
ICD-10 Finland
Dental examination
1.3
8.8
789
6522
Z71.8
ICD-10 Finland
Other specified counselling
1.4
8.8
423
3146
AA1AD
NOMESCO Finland
CT of head and brain
1.5
8.8
367
2653
H26.4
ICD-10 Finland
After-cataract
2.0
8.8
114
597
J01MA14
ATC
moxifloxacin; systemic
1.8
8.7
157
919
A03
ICPC
Fever
1.5
8.7
293
2022
A07EA06
ATC
budesonide; oral, local oral
2.3
8.7
75
326
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.1
8.6
45
147
R05FA02
ATC
opium derivatives and expectorants; systemic
1.3
8.6
736
6030
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
2.6
8.6
59
228
R21
ICPC
Throat symptom/complaint
1.5
8.6
373
2719
L03
ICPC
Low back symptom/complaint
1.4
8.6
418
3114
L04AD01
ATC
ciclosporin; systemic
3.0
8.6
47
159
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.9
8.6
118
629
S01EC04
ATC
brinzolamide; ophthalmic
2.9
8.5
50
176
K51.5
ICD-10 Finland
Left sided colitis
2.5
8.5
62
248
KMAK
NOMESCO Finland
NA
1.3
8.5
1033
8912
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
27.6
8.5
11
*
WX110
NOMESCO Finland
Local anesthesy
1.3
8.5
1338
11982
M01AX17
ATC
nimesulide; oral
1.4
8.4
414
3093
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
4.1
8.4
31
77
R4120
NOMESCO Finland
Occupational therapy
2.0
8.3
110
576
D07AC13
ATC
mometasone; topical
1.4
8.3
516
4010
36400
ICD-8 Finland
Iritis, Iridocyclitis acuta
+∞
8.3
8
*
36904
ICD-8 Finland
Other inflammatory diseases of eye, Scleritis
+∞
8.3
8
*
K50.1
ICD-10 Finland
Crohn disease of large intestine
3.7
8.3
34
92
H66.9
ICD-10 Finland
Otitis media, unspecified
2.0
8.3
106
552
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
8.2
408
3046
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.1
8.2
94
465
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.6
8.2
204
1309
CF2S4
NOMESCO Finland
Photography of conjunctiva
14.5
8.2
13
9
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
8.2
492
3803
XQ800
NOMESCO Finland
Prick test
1.7
8.2
155
922
M01AH02
ATC
rofecoxib; oral
1.6
8.1
214
1393
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
8.1
727
5985
WZC30
NOMESCO Finland
Teaching
1.6
8.1
220
1445
M54.6
ICD-10 Finland
Pain in thoracic spine
1.8
8.1
133
754
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
8.1
401
2998
H30.2
ICD-10 Finland
Posterior cyclitis
17.2
8.1
12
7
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
11.7
8.1
14
12
S01EE05
ATC
tafluprost; ophthalmic
2.8
8.0
49
178
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
10.1
8.0
15
15
CG2S4
NOMESCO Finland
Photography of cornea
22.1
8.0
11
5
S01EA03
ATC
apraclonidine; ophthalmic
6.3
8.0
20
32
J01DA01
ATC
[U] cefalexin; systemic
1.3
8.0
1213
10753
R52.2
ICD-10 Finland
Other chronic pain
2.3
8.0
68
297
J01DA06
ATC
[U] cefuroxime; systemic
1.5
8.0
273
1892
WX290
NOMESCO Finland
Other blockade of nerve
1.3
7.9
857
7246
K08.80
ICD-10 Finland
Toothache NOS
1.7
7.9
158
952
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
3.9
7.9
31
81
J01EA01
ATC
trimethoprim; systemic
1.4
7.9
451
3457
H03.1
ICD-10 Finland
Involvement of eyelid in other infectious diseases classified elsewhere
13.1
7.9
13
10
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
7.8
7.9
17
22
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
7.9
223
1477
G44.8
ICD-10 Finland
Other specified headache syndromes
3.7
7.8
32
87
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.8
7.8
141
825
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
7.8
198
1277
R01AD08
ATC
fluticasone; nasal
1.3
7.7
556
4423
J45.1
ICD-10 Finland
Nonallergic asthma
1.8
7.7
119
661
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.1
7.7
40
131
S01KA02
ATC
hypromellose; ophthalmic
3.4
7.7
35
104
R03BA02
ATC
budesonide; inhalant
1.5
7.7
308
2206
H53.2
ICD-10 Finland
Diplopia
2.6
7.7
54
214
R03BA01
ATC
beclometasone; inhalant
1.5
7.6
248
1697
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
7.6
314
2264
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
2.8
7.6
46
167
D06BX01
ATC
metronidazole; topical
1.6
7.6
198
1288
WX002
NOMESCO Finland
Sedation and analgesia
1.5
7.6
311
2235
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.5
7.6
59
244
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
7.6
1004
8707
L71.9
ICD-10 Finland
Rosacea, unspecified
2.6
7.6
52
201
R13
ICD-10 Finland
Dysphagia
2.0
7.5
98
513
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.5
7.5
57
235
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.7
7.5
149
896
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
3.4
7.5
34
101
L17
ICPC
Foot/toe symptom/complaint
1.4
7.5
418
3186
R02
ICPC
Shortness of breath/dyspnoea
1.6
7.4
190
1228
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
7.4
455
3523
R31
ICD-10 Finland
Unspecified haematuria
1.8
7.4
124
711
L01AA01
ATC
cyclophosphamide; systemic
7.7
7.4
16
21
F73
ICPC
Eye infection/inflammation other
3.0
7.4
39
130
H50.1
ICD-10 Finland
Divergent concomitant strabismus
5.6
7.4
20
36
R11
ICD-10 Finland
Nausea and vomiting
1.8
7.4
127
734
S01GX02
ATC
levocabastine; ophthalmic
1.8
7.3
123
702
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
2.7
7.3
48
183
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
+∞
7.3
7
*
3641A
ICD-9 Finland
Disorders of iris and ciliary body, Chronic iridocyclitis
+∞
7.3
7
*
D07AD01
ATC
clobetasol; topical
1.5
7.2
268
1891
S04
ICPC
Lump/swelling localized
1.7
7.2
151
927
J01AA04
ATC
lymecycline; systemic
1.5
7.2
240
1653
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
30.1
7.1
9
*
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
2.5
7.1
54
223
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.6
7.1
179
1152
S01ED02
ATC
betaxolol; ophthalmic
5.3
7.1
20
38
XF404
NOMESCO Finland
Ambulatory ECG
1.7
7.1
138
827
A98
ICPC
Health maint/preventive medicine
1.7
7.1
2007
19432
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
7.1
537
4301
R06AX22
ATC
ebastine; oral
1.4
7.0
334
2473
L08
ICPC
Shoulder symptom/complaint
1.4
7.0
305
2220
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
1.7
7.0
131
778
M31.3
ICD-10 Finland
Wegener granulomatosis
7.0
7.0
16
23
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
7.0
473
3719
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.5
7.0
228
1565
L01
ICPC
Neck symptom/complaint
1.5
7.0
239
1654
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
4.0
7.0
26
66
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
4.0
7.0
26
66
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.1
6.9
78
386
G43.9
ICD-10 Finland
Migraine, unspecified
1.8
6.9
118
682
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
6.9
827
7051
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.9
6.9
101
556
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.6
6.9
159
1000
M10.9
ICD-10 Finland
Gout, unspecified
2.0
6.8
80
404
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
6.8
676
5616
L12
ICPC
Hand/finger symptom/complaint
1.5
6.8
230
1587
WZA90
NOMESCO Finland
Other doctors statement
1.4
6.8
408
3143
L71.8
ICD-10 Finland
Other rosacea
3.3
6.8
32
99
UJH02
NOMESCO Finland
Anoscopy
2.0
6.8
79
396
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
6.7
253
1785
K07.60
ICD-10 Finland
Snapping jaw
1.8
6.7
105
589
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
2.7
6.7
41
151
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.4
6.7
52
219
J45
ICD-10 Finland
Asthma
1.6
6.7
165
1056
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
22.6
6.7
9
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
6.7
162
1035
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
3.7
6.7
27
74
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.8
6.6
106
600
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.8
6.6
113
651
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
4.0
6.6
24
60
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.9
6.6
96
524
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
1.9
6.6
90
480
Z3226
NOMESCO Finland
Physiotherapist
1.4
6.6
303
2227
X58
ICD-10 Finland
Exposure to other specified factors
1.5
6.6
230
1602
J01DC02
ATC
cefuroxime; systemic
1.8
6.5
109
624
R4110
NOMESCO Finland
Physiotherapy
1.3
6.5
437
3425
A01
ICPC
Pain general/multiple sites
1.7
6.5
125
749
R51.81
ICD-10 Finland
Facial pain NOS
2.4
6.5
50
209
R01AD12
ATC
fluticasone furoate; nasal
1.3
6.5
581
4754
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
1.8
6.5
103
581
A11
ICPC
Chest pain NOS
1.8
6.5
110
632
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.1
6.4
70
342
T15.1
ICD-10 Finland
Foreign body in conjunctival sac
3.4
6.4
29
87
S01FA06
ATC
tropicamide; ophthalmic
70.0
6.4
7
*
C07AA05
ATC
propranolol; systemic
1.4
6.4
350
2653
K51.8
ICD-10 Finland
Other ulcerative colitis
3.2
6.4
31
98
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.8
6.4
108
622
M01AB55
ATC
diclofenac, combinations; oral
1.8
6.4
108
622
N05CF01
ATC
zopiclone; oral
1.3
6.4
517
4169
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
3.0
6.4
34
115
G44.0
ICD-10 Finland
Cluster headache syndrome
3.3
6.3
29
88
L04AA17
ATC
[U] adalimumab; parenteral
8.2
6.3
13
16
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
5.5
6.3
17
31
CG2T4
NOMESCO Finland
Topography assessment of cornea
9.3
6.3
12
13
H46
ICD-10 Finland
Optic neuritis
3.7
6.3
25
68
H17.1
ICD-10 Finland
Other central corneal opacity
+∞
6.3
6
*
H22.1
ICD-10 Finland
Iridocyclitis in other diseases classified elsewhere
+∞
6.3
6
*
M08.1
ICD-10 Finland
Juvenile ankylosing spondylitis
+∞
6.3
6
*
H31.4
ICD-10 Finland
Choroidal detachment
+∞
6.3
6
*
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
2.6
6.2
44
174
SHA04
NOMESCO Finland
Correction of physiology of bite - very demanding therapy visit
3.2
6.2
30
95
C01CA24
ATC
epinephrine; parenteral
1.7
6.2
120
720
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
6.2
115
684
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
6.2
204
1404
Z2221
NOMESCO Finland
Medical doctor
1.3
6.1
495
3984
J31.0
ICD-10 Finland
Chronic rhinitis
1.6
6.1
139
875
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
6.1
180
1210
M01CB01
ATC
sodium aurothiomalate; parenteral
3.1
6.1
30
97
J01MA06
ATC
norfloxacin; oral
1.5
6.1
228
1611
M54.8
ICD-10 Finland
Other dorsalgia
2.0
6.1
68
340
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.1
6.0
65
318
H11.4
ICD-10 Finland
Other conjunctival vascular disorders and cysts
4.4
6.0
20
46
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
6.0
855
7410

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: H7_SCLERITISEPISCLERITIS – Scleritis and episcleritis

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).