No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
490 |
4. Check minimum number of eventsNone |
490 |
5. Include endpointsNone |
490 |
6. Filter based on genotype QC (FinnGen only) |
474 |
Control definitions (FinnGen only)
- Control exclude
- H7_SCLERACORNEA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H15
- Name in latin
- Scleritis
Similar endpoints
↥List of similar endpoints to
Scleritis
based on the number of shared cases.
Similar with more cases:
- Scleritis and episcleritis
- Disorders of sclera, cornea, iris and ciliary body
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2446 | 1435 | 995 |
| Only index persons | 2329 | 1379 | 950 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.03 |
| Only index persons | 0.04 | 0.05 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 51.11 | 53.37 | 48.04 |
| Only index persons | 50.92 | 53.12 | 47.73 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 474 | 323 | 151 |
| Unadjusted period prevalence (%) | 0.10 | 0.11 | 0.07 |
| Median age at first event (years) | 53.81 | 52.58 | 56.44 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 490
- Matched controls
- 4900
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H15.0
ICD-10 Finland
Scleritis
+∞
307.7
479
*
H15.1
ICD-10 Finland
Episcleritis
401.1
189.4
179
7
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
419.9
130.2
125
*
H57.1
ICD-10 Finland
Ocular pain
17.2
125.3
113
84
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
5.0
69.8
272
976
H16.0
ICD-10 Finland
Corneal ulcer
16.3
65.8
58
40
S01BC03
ATC
diclofenac; ophthalmic
17.7
60.6
51
32
H02AB06
ATC
prednisolone; systemic
4.7
56.6
346
1663
L04AX03
ATC
methotrexate; systemic
5.7
52.3
114
246
S01BA01
ATC
dexamethasone; ophthalmic
10.1
50.0
60
67
H04.10
ICD-10 Finland
Dry eye syndrome
5.0
48.3
128
326
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.8
45.9
293
1384
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
5.1
43.8
109
262
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.0
41.4
155
508
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
5.9
41.0
81
158
L04AX01
ATC
azathioprine; systemic
7.8
37.6
55
78
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
108.7
37.3
40
*
S01BA04
ATC
prednisolone; ophthalmic
14.5
36.9
34
25
XCW99
NOMESCO Finland
Other investigative procedure of eye
4.6
33.2
90
229
A02BC02
ATC
pantoprazole; systemic
4.0
33.1
401
2606
H16.9
ICD-10 Finland
Keratitis, unspecified
125.4
33.1
35
*
H20.1
ICD-10 Finland
Chronic iridocyclitis
+∞
32.7
31
*
A07EC01
ATC
sulfasalazine; oral, rectal
4.8
28.8
72
171
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
28.7
266
1439
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
4.8
26.4
64
148
F01
ICPC
Eye pain
6.8
24.7
40
63
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.6
24.7
64
156
H02AB07
ATC
prednisone; oral
3.3
23.4
104
369
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
4.8
22.8
55
126
XCD10
NOMESCO Finland
Electrophysiological examination of eye
8.0
22.3
31
41
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
20.8
196
1027
S01AD03
ATC
aciclovir; ophthalmic
6.9
20.7
33
51
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
7.1
20.6
32
48
S01ED51
ATC
timolol, combinations; ophthalmic
4.5
20.4
53
129
L04AA13
ATC
[U] leflunomide
8.4
18.9
25
31
L01BA01
ATC
methotrexate; systemic
6.3
18.5
32
54
F02
ICPC
Red eye
4.9
18.1
41
89
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.5
18.0
68
216
H11.3
ICD-10 Finland
Conjunctival haemorrhage
4.9
17.1
39
85
S01BC05
ATC
ketorolac; ophthalmic
5.4
16.2
33
65
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.7
16.0
55
164
S01ED01
ATC
timolol; ophthalmic
6.5
15.6
26
42
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
24.3
15.2
21
9
R51.80
ICD-10 Finland
Headache
2.5
15.1
110
501
L04AB04
ATC
adalimumab; parenteral
6.0
14.6
26
45
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
5.9
14.3
26
46
M25.5
ICD-10 Finland
Pain in joint
2.1
14.2
197
1175
H10
ICD-10 Finland
Conjunctivitis
3.4
14.0
53
168
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.9
13.7
68
254
P01BA02
ATC
hydroxychloroquine; oral
3.1
13.6
61
215
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
13.4
154
850
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.1
12.8
58
205
H20.8
ICD-10 Finland
Other iridocyclitis
+∞
12.6
12
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.3
12.4
48
154
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
27.5
12.1
16
6
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
5.9
12.1
22
39
L88
ICPC
Rheumatoid/seropositive arthritis
4.3
11.8
31
76
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.7
11.6
67
271
36904
ICD-8 Finland
Other inflammatory diseases of eye, Scleritis
+∞
11.5
11
*
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
4.3
11.3
30
74
M13.9
ICD-10 Finland
Arthritis, unspecified
3.1
11.3
49
169
XCK10
NOMESCO Finland
Photography of fundus of eye
2.8
11.2
59
227
H53.1
ICD-10 Finland
Subjective visual disturbances
3.1
11.2
49
170
XCH00
NOMESCO Finland
Eye pressure measurement
4.1
11.0
31
80
F29
ICPC
Eye symptom/complaint other
2.6
10.7
64
263
R51
ICD-10 Finland
Headache
3.3
10.4
41
133
H20
ICD-10 Finland
Iridocyclitis
24.0
10.3
14
6
J01MA12
ATC
levofloxacin; systemic
2.2
10.0
96
487
K50.8
ICD-10 Finland
Other Crohn disease
7.9
10.0
22
29
M05BA04
ATC
alendronic acid; oral
3.0
9.8
46
166
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.7
9.6
53
209
UJF32
NOMESCO Finland
Coloscopy
2.0
9.5
129
747
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
101.9
9.4
10
*
CF2S4
NOMESCO Finland
Photography of conjunctiva
101.9
9.4
10
*
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
+∞
9.4
9
*
CS494
NOMESCO Finland
Other visual field testing
5.0
9.4
20
41
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.5
9.3
32
95
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
9.2
144
873
J01MA02
ATC
ciprofloxacin; systemic
1.8
9.0
184
1212
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
9.0
103
559
L04AA06
ATC
mycophenolic acid; systemic
8.2
8.9
19
24
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
12.8
8.9
15
12
E0000UV, ,
ATC
1.8
8.9
211
1453
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
8.7
140
854
H16.2
ICD-10 Finland
Keratoconjunctivitis
50.9
8.7
10
*
H53.2
ICD-10 Finland
Diplopia
4.1
8.7
24
61
UJF30
NOMESCO Finland
Ileoscopy through colon
2.5
8.7
60
264
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
8.6
108
606
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
8.5
98
532
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
4.4
8.5
21
49
N02AX02
ATC
tramadol; systemic, rectal
1.8
8.4
212
1479
D07AC01
ATC
betamethasone; topical
1.8
8.4
182
1215
XCK00
NOMESCO Finland
Perimetry
3.1
8.4
35
118
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.4
8.4
61
275
C10AC01
ATC
colestyramine; oral
4.3
8.3
21
50
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.2
8.2
33
109
ZXA05
NOMESCO Finland
Left side
1.9
8.1
120
710
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
17.5
8.1
12
7
J01FA09
ATC
clarithromycin; systemic
1.8
8.1
170
1124
M45
ICD-10 Finland
Ankylosing spondylitis
7.4
8.0
18
25
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
4.8
7.9
18
39
J01AA02
ATC
doxycycline; systemic
1.9
7.9
385
3223
J02AC01
ATC
fluconazole; systemic
1.7
7.9
216
1536
S01GX01
ATC
cromoglicic acid; ophthalmic
1.9
7.8
115
680
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.1
7.7
86
460
A02BC03
ATC
lansoprazole; oral
1.8
7.7
144
915
S01FA04
ATC
cyclopentolate; ophthalmic
15.3
7.7
12
8
S01EC04
ATC
brinzolamide; ophthalmic
4.1
7.7
21
53
M01AE02
ATC
naproxen; oral, rectal
1.7
7.7
293
2276
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.7
7.6
43
171
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3.0
7.5
34
120
N02BE01
ATC
paracetamol; systemic, rectal
2.3
7.5
439
3871
H18.8
ICD-10 Finland
Other specified disorders of cornea
81.3
7.4
8
*
S01EA05
ATC
brimonidine; ophthalmic
7.0
7.3
17
25
H18.4
ICD-10 Finland
Corneal degeneration
+∞
7.3
7
*
L04AD01
ATC
ciclosporin; systemic
6.4
7.3
18
29
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.0
7.2
20
51
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
7.1
103
604
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
7.0
257
1956
K50.9
ICD-10 Finland
Crohn disease, unspecified
6.5
7.0
17
27
M79.6
ICD-10 Finland
Pain in limb
1.7
7.0
207
1491
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.2
7.0
27
87
R06AE07
ATC
cetirizine; oral
1.7
7.0
221
1620
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.4
7.0
48
211
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
6.9
179
1243
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
6.7
89
505
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
3.0
6.7
29
100
M54.5
ICD-10 Finland
Low back pain
1.7
6.7
180
1261
G51.0
ICD-10 Finland
Bell palsy
4.3
6.6
17
41
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
8.9
6.6
13
15
L04AA01
ATC
[U] ciclosporin
10.2
6.6
12
12
R07.3
ICD-10 Finland
Other chest pain
2.2
6.5
55
264
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
7.5
6.5
14
19
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.3
6.4
47
212
ZX120
NOMESCO Finland
Intravenous
2.3
6.4
50
232
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
4.2
6.4
17
42
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.3
6.4
23
71
J01FA10
ATC
azithromycin; systemic
1.6
6.3
297
2379
J01DB01
ATC
cefalexin; oral
1.9
6.3
404
3514
S01EE01
ATC
latanoprost; ophthalmic
3.0
6.3
28
98
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
6.3
6
*
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
27.0
6.2
8
*
S01GX02
ATC
levocabastine; ophthalmic
2.5
6.1
37
153
S01XA18
ATC
ciclosporin; ophthalmic
12.7
6.1
10
8
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.3
6.1
23
73
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
6.1
212
1576
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.6
6.1
20
58
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
142
165
11.71
118.56
1.6
2.5
35.36
39.75
u/l
1.51
137
152
101
116
10.71
83.70
1.8
1.5
—
145.71
—
0
7
129
305
5.38
53.50
2.5
2.4
32.00
15.78
au/ml
—
9
18
56
64
9.75
45.78
1.5
1.2
156.00
—
titre
—
5
0
202
748
3.89
45.76
1.6
1.3
62.71
32.72
iu/ml
0.53
64
254
66
121
6.15
35.44
1.7
1.6
0.10
0.05
iu/ml
0.23
13
17
367
2319
3.32
30.34
12.7
8.9
4.22
4.02
e9/l
1.05
342
2036
325
1929
3.03
29.82
10.2
5.6
28.75
28.39
%
0.26
319
1814
317
1863
2.99
29.49
10.2
5.5
2.85
2.81
%
0.11
311
1741
320
1906
2.96
28.74
10.0
5.4
56.77
57.10
%
0.21
314
1788
61
129
5.26
27.93
1.8
1.4
0.23
0.24
g/l
0.47
56
124
62
136
5.07
27.21
1.8
1.4
1.24
1.23
g/l
0.06
57
130
414
2980
3.51
24.14
7.5
3.8
13.01
10.86
mm/h
2.19
404
2768
34
16
22.73
23.78
1.3
3.9
459.56
673.94
u/ml
0.50
34
16
153
730
2.59
19.63
1.4
1.3
2.65
9.98
u/ml
2.77
45
300
59
162
4.00
19.36
1.3
1.2
1.14
1.16
u/ml
—
5
10
54
146
4.03
18.07
1.3
1.6
—
—
—
0
0
25
35
7.47
17.10
1.4
1.1
—
—
—
0
0
25
35
7.47
17.10
1.4
1.1
—
—
—
0
0
400
3041
2.72
16.90
10.7
7.0
73.93
76.82
u/l
0.84
391
2857
293
1948
2.25
16.85
7.8
4.4
0.00
0.00
estimate
0.50
48
386
25
36
7.26
16.69
1.4
1.1
—
—
—
0
0
25
36
7.26
16.69
1.4
1.1
—
—
—
0
0
25
36
7.26
16.69
1.4
1.1
—
—
—
0
0
25
36
7.26
16.69
1.2
1.2
—
—
—
0
0
20
5
41.63
16.45
1.4
1.0
—
—
—
0
0
217
1289
2.23
16.37
5.1
2.9
—
—
—
0
0
291
1947
2.22
16.24
5.8
3.2
0.00
0.00
estimate
0.50
52
402
292
1968
2.20
15.84
5.8
3.2
0.00
0.02
estimate
0.80
44
373
253
1626
2.15
15.34
7.2
5.4
1.21
1.22
mmol/l
0.63
239
1481
120
580
2.42
14.46
3.9
2.6
0.62
1.11
e6/l
2.21
78
323
27
49
5.77
14.46
1.0
1.1
—
—
—
0
0
43
117
3.93
14.22
1.2
1.2
3.61
2.64
u/ml
—
7
17
43
118
3.90
14.06
1.2
1.2
1.95
6.37
u/ml
—
8
23
248
1625
2.07
13.81
3.2
2.2
76.13
75.75
nmol/l
0.07
234
1473
264
1788
2.03
13.23
8.2
6.3
1.21
1.22
mmol/l
0.21
234
1525
65
257
2.76
11.72
5.0
3.4
84.16
75.51
ng/l
0.35
60
239
23
44
5.44
11.64
1.3
1.2
—
—
—
0
0
468
4090
4.21
11.49
21.0
12.0
16.67
21.92
mg/l
4.46
411
3152
229
1553
1.89
10.67
5.7
4.4
36.19
36.18
g/l
0.01
214
1455
151
903
1.97
10.19
2.6
2.1
2.65
3.11
mg/l
1.74
140
776
105
556
2.13
9.85
1.9
1.8
—
—
—
0
0
292
2187
1.83
9.49
5.6
4.2
6.43
6.57
mmol/l
0.55
278
2038
29
80
3.79
9.41
2.3
1.5
8062.83
10169.51
e6/l
0.21
23
61
206
1393
1.83
9.35
3.9
3.3
34.58
32.55
ng/l
0.05
140
881
172
1104
1.86
9.21
2.2
2.0
203.10
173.73
u/l
0.12
165
1045
159
996
1.88
9.19
4.6
2.9
0.15
0.36
e6/l
2.32
120
743
65
296
2.38
8.72
5.7
3.2
1.26
1.96
mmol/l
0.92
60
246
28
81
3.61
8.50
2.1
1.3
—
—
—
0
0
82
417
2.16
8.46
6.9
6.1
104.50
104.03
mmol/l
0.44
82
417
167
1086
1.82
8.44
4.6
3.0
28.89
132.80
e6/l
0.99
132
830
18
37
5.01
8.42
1.1
1.1
—
—
—
0
0
17
20
8.76
8.37
1.2
1.2
—
—
—
0
0
47
187
2.67
8.35
1.5
1.5
—
—
—
0
0
16
19
8.66
7.87
1.3
1.2
—
—
—
0
0
226
1631
1.72
7.80
15.4
10.3
1.17
1.16
inr
0.03
61
507
76
389
2.13
7.69
1.9
1.8
—
—
—
0
0
75
383
2.13
7.63
1.8
1.8
—
—
—
0
0
11
6
18.71
7.63
1.0
1.0
—
—
—
0
0
121
736
1.86
7.47
3.6
2.5
3.82
7.34
e6/l
1.98
110
669
54
244
2.36
7.36
1.5
1.5
—
—
—
0
0
26
79
3.42
7.35
1.4
1.2
—
—
—
0
0
213
1535
1.69
7.24
5.8
3.3
—
—
—
0
0
25
75
3.46
7.20
1.5
1.2
279.30
225.36
u/ml
0.43
18
43
93
525
1.95
7.18
2.2
1.9
29.49
29.59
s
0.06
93
512
201
1438
1.67
6.95
2.2
1.9
98.87
95.83
pmol/l
0.29
97
755
458
4140
2.63
6.90
19.3
13.2
139.68
139.71
mmol/l
0.13
453
4030
459
4155
2.65
6.86
19.5
13.3
3.94
3.95
mmol/l
0.40
453
4033
430
3795
2.09
6.76
5.6
4.7
1.88
2.15
mu/l
0.38
401
3514
179
1253
1.68
6.66
2.6
3.4
2.36
2.35
mmol/l
0.61
158
1111
260
2001
1.64
6.65
5.8
6.0
9.87
10.49
umol/l
0.65
251
1898
39
159
2.58
6.62
4.8
2.3
0.72
0.64
%
0.81
39
159
94
547
1.89
6.60
4.0
2.7
4.74
3.33
e6/l
0.31
49
291
104
626
1.84
6.57
2.1
2.7
2.45
2.44
mmol/l
0.49
90
549
152
1025
1.70
6.48
6.6
3.5
0.00
0.00
estimate
0.50
49
379
32
119
2.81
6.48
1.4
1.2
—
—
—
0
0
148
991
1.71
6.47
3.4
2.4
5190.75
6910.64
umol/l
0.19
138
888
33
127
2.71
6.27
2.0
2.0
—
—
—
0
0
135
889
1.72
6.24
1.9
1.7
0.91
0.95
mg/l
0.10
103
682
241
1842
1.61
6.19
3.5
2.7
115.23
97.74
ug/l
0.96
229
1718
29
105
2.87
6.16
1.1
1.1
—
—
—
0
0
22
68
3.34
6.07
1.3
1.5
—
—
—
0
0
29
106
2.85
6.06
1.2
1.3
—
—
—
0
0
129
850
1.70
5.92
1.5
1.5
19.33
21.43
nmol/l
0.86
115
733
169
1197
1.63
5.86
3.1
2.3
54.68
59.66
u/l
0.76
155
1117
127
837
1.70
5.81
6.6
3.4
1.01
1.02
kg/l
0.77
18
112
96
588
1.79
5.68
1.6
1.7
1345.34
1211.57
nmol/l
0.58
78
442
472
4388
3.06
5.63
16.5
9.4
26.74
26.32
u/l
0.11
463
4258
21
67
3.23
5.53
1.8
1.3
109.88
113.72
u/ml
—
8
18
53
268
2.10
5.52
2.6
2.4
3.98
6.27
ug/l
1.58
46
242
59
311
2.02
5.50
2.1
2.2
67.61
69.32
ml/min/173m2
0.09
23
123
26
95
2.83
5.45
1.1
1.1
2.00
3.43
e6/l
0.72
21
74
22
73
3.11
5.44
3.4
3.6
56.64
59.37
%
0.34
22
73
135
923
1.64
5.31
2.5
2.1
—
—
—
0
0
9
8
11.43
5.31
1.0
1.0
107.00
102.75
%
—
9
8
21
70
3.09
5.16
3.2
3.2
3.97
4.65
e9/l
0.52
21
70
42
200
2.20
5.09
6.7
7.9
0.78
0.66
%
1.23
42
200
28
111
2.61
5.05
1.1
1.2
360.82
430.62
mg/l
1.05
28
105
80
482
1.79
4.97
3.1
2.2
22.97
22.87
%
0.02
73
422
13
24
5.53
4.94
4.4
3.1
—
—
—
0
0
13
25
5.31
4.80
2.0
1.6
884.38
654.36
e6/l
0.71
13
25
14
31
4.62
4.59
1.0
1.1
—
—
—
0
0
123
854
1.59
4.46
1.9
1.5
—
—
—
0
0
364
3178
1.57
4.46
4.8
4.0
14.78
14.59
pmol/l
0.78
338
2921
132
937
1.56
4.34
3.4
2.9
813.23
992.50
ng/l
0.42
117
782
11
20
5.60
4.31
2.6
2.2
—
—
—
0
0
62
364
1.81
4.20
2.0
1.8
329.86
379.82
nmol/l
1.22
56
342
10
17
5.98
4.15
1.0
1.1
1320.70
1583.47
miu/ml
—
10
17
134
964
1.54
4.13
1.4
1.2
1.25
1.61
u/ml
0.31
33
285
16
52
3.15
4.12
1.1
1.3
0.64
0.52
nmol/l
0.87
16
47
13
31
4.28
4.04
2.6
1.1
—
—
—
0
0
24
100
2.47
3.95
1.1
1.2
3.92
3.76
mmol/l
0.24
24
93
481
4624
3.19
3.95
30.7
17.9
135.40
135.76
g/l
0.23
481
4564
32
152
2.18
3.94
6.0
3.4
58.05
47.49
%
1.46
32
152
50
284
1.85
3.77
1.7
1.9
—
—
—
0
0
331
2880
1.46
3.71
3.3
3.3
—
—
—
0
0
8
12
6.76
3.68
2.0
1.8
—
—
—
0
0
21
85
2.54
3.68
1.1
1.1
—
—
—
0
0
11
26
4.30
3.52
1.0
1.0
—
—
—
0
0
16
58
2.82
3.45
1.1
1.1
—
—
—
0
0
18
70
2.63
3.42
1.6
1.3
—
—
—
0
0
18
70
2.63
3.42
1.6
1.3
—
—
—
0
0
28
135
2.14
3.35
3.5
2.2
1.86
1.47
g/l
0.65
23
117
14
48
2.97
3.32
1.4
1.6
—
—
—
0
0
23
103
2.29
3.27
4.0
4.3
3.92
3.82
mmol/l
0.39
23
103
16
60
2.72
3.26
2.7
2.7
—
982.00
—
0
6
57
353
1.70
3.23
3.8
2.2
24.90
33.28
u/l
1.65
49
303
427
3957
1.62
3.17
4.7
4.1
5.84
5.85
mmol/l
0.04
409
3659
14
50
2.85
3.11
1.7
2.1
12.71
23.22
mg/l
—
7
15
94
664
1.51
3.09
3.8
3.4
532.35
317.30
ng/l
0.19
71
463
480
4619
2.92
3.08
30.6
17.7
40.62
40.41
%
0.50
467
4370
23
106
2.23
3.08
3.3
2.8
—
—
—
0
0
70
465
1.59
3.02
10.0
6.2
—
—
—
0
0
27
134
2.07
3.02
1.4
1.6
—
—
—
0
0
421
3909
1.55
2.87
17.1
10.9
83.85
85.06
ml/min/173m2
0.54
373
3184
15
59
2.59
2.81
1.6
1.8
—
—
—
0
0
12
39
3.13
2.79
1.5
1.8
—
—
—
0
0
142
1108
1.40
2.75
4.6
3.8
22.91
9.46
mg/mmol
1.23
99
687
39
228
1.77
2.72
1.4
1.8
—
—
—
0
0
11
35
3.19
2.66
1.5
1.9
—
—
—
0
0
5
7
7.20
2.55
1.0
1.0
—
—
—
0
0
9
26
3.51
2.49
1.2
1.1
—
—
—
0
0
146
1163
1.36
2.47
3.9
3.1
7.62
7.54
mmol/l
0.06
132
993
10
32
3.17
2.45
1.5
1.1
—
—
—
0
0
9
27
3.38
2.40
1.0
1.7
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
17
77
2.25
2.40
2.2
2.5
0.35
0.35
u/ml
—
10
43
402
3732
1.43
2.40
6.0
5.1
39.33
39.19
mmol/mol
0.10
384
3503
34
199
1.76
2.39
2.7
3.0
0.92
1.88
mmol/l
0.88
27
146
13
52
2.54
2.37
1.0
1.1
—
—
—
0
0
12
46
2.65
2.37
1.3
1.4
—
—
—
0
0
12
46
2.65
2.37
1.3
1.4
—
—
—
0
0
17
78
2.22
2.33
1.6
1.6
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
9
28
3.25
2.31
1.0
1.1
—
—
—
0
0
9
28
3.25
2.31
1.0
1.1
—
—
—
0
0
24
127
1.94
2.30
2.7
3.4
24.70
24.97
mmol/l
0.18
24
122
10
34
2.98
2.29
1.4
1.7
—
—
—
0
0
10
34
2.98
2.29
1.4
1.7
—
—
—
0
0
10
34
2.98
2.29
1.4
1.7
—
—
—
0
0
12
47
2.59
2.28
1.3
1.4
—
—
—
0
0
7
18
3.93
2.26
1.1
1.6
—
—
—
0
0
13
54
2.45
2.21
1.0
1.1
—
—
—
0
0
12
48
2.54
2.20
1.3
1.3
—
—
—
0
0
12
48
2.54
2.20
1.3
1.4
—
—
—
0
0
12
48
2.54
2.20
1.3
1.4
—
—
—
0
0
6
14
4.32
2.15
2.7
5.9
—
—
—
0
0
54
368
1.53
2.12
6.4
7.1
0.20
1.25
mmol/l
1.62
47
301
23
126
1.87
2.02
1.4
1.6
—
—
—
0
0
17
84
2.06
1.98
1.6
1.7
—
—
—
0
0
14
64
2.22
1.96
1.4
1.7
—
—
—
0
0
14
64
2.22
1.96
1.4
1.7
—
—
—
0
0
5
11
4.58
1.94
1.4
3.1
117.00
128.82
%
—
5
11
20
106
1.92
1.93
2.8
2.1
213.87
241.09
ug/l
0.06
15
98
13
58
2.28
1.92
1.5
1.2
—
—
—
0
0
14
65
2.19
1.89
1.1
1.1
—
—
—
0
0
39
254
1.58
1.88
2.8
3.5
4.37
4.63
pmol/l
0.93
30
226
60
431
1.45
1.84
2.5
2.3
5.22
6.75
umol/l
1.08
52
372
6
17
3.56
1.84
1.0
1.3
—
—
—
0
0
164
1379
1.28
1.83
2.6
3.1
32.29
31.33
u/l
0.11
156
1316
8
29
2.79
1.80
2.8
4.5
—
—
—
0
0
14
67
2.12
1.77
1.4
1.6
—
—
—
0
0
9
36
2.53
1.74
1.0
1.0
—
—
—
0
0
13
61
2.16
1.73
1.4
1.2
—
—
—
0
0
6
19
3.18
1.66
1.0
1.0
—
—
—
0
0
14
69
2.06
1.66
1.7
2.0
129.29
131.04
g/l
—
7
53
23
135
1.74
1.65
1.6
1.8
—
—
—
0
0
212
1857
1.25
1.65
2.9
2.4
—
—
—
0
0
11
49
2.27
1.64
1.5
1.6
—
—
—
0
0
10
42
2.41
1.62
2.9
2.3
—
—
—
0
0
5
14
3.60
1.62
1.2
3.1
187.40
207.57
u/l
—
5
14
11
50
2.23
1.58
1.6
1.6
—
—
—
0
0
10
44
2.30
1.56
1.5
1.6
—
—
—
0
0
10
44
2.30
1.56
1.5
1.6
—
—
—
0
0
13
64
2.06
1.55
1.2
1.1
—
—
—
0
0
5
15
3.36
1.52
1.0
1.1
—
—
—
0
0
314
2891
1.24
1.49
3.2
2.9
43.11
43.92
u/l
0.07
300
2731
13
66
2.00
1.44
2.2
1.5
—
—
—
0
0
5
16
3.15
1.44
1.4
2.1
75.12
63.98
ug/l
—
5
16
5
16
3.15
1.44
1.2
1.3
13.20
14.88
u/l
—
5
16
16
88
1.85
1.43
1.6
1.7
—
—
—
0
0
28
182
1.57
1.40
3.8
2.7
0.46
0.15
e6/l
0.40
28
175
7
29
2.43
1.39
1.1
1.2
1.75
1.89
mmol/l
—
7
29
10
47
2.15
1.34
1.0
1.1
—
—
—
0
0
15
84
1.81
1.28
1.1
1.1
0.51
2.73
u/ml
—
8
43
70
552
1.31
1.26
1.8
2.0
—
—
—
0
0
11
56
1.99
1.23
1.5
1.5
—
—
—
0
0
62
483
1.32
1.22
1.7
1.9
—
—
—
0
0
5
19
2.65
1.22
1.2
1.5
35.97
31.42
umol/l
—
5
19
5
19
2.65
1.22
1.2
1.1
—
—
—
0
0
32
223
1.47
1.20
1.9
1.5
—
—
—
0
0
14
80
1.77
1.14
1.1
1.0
1.88
1.49
u/ml
—
5
40
432
4168
1.31
1.13
5.2
4.5
2.85
2.85
mmol/l
0.06
411
3896
27
185
1.49
1.11
1.5
1.4
—
—
—
0
0
14
82
1.73
1.06
1.4
1.4
—
—
—
0
0
90
754
1.24
1.02
1.6
1.6
103750431.20
42438715.32
pmol/l
0.25
80
648
20
131
1.55
1.01
1.8
1.7
—
—
—
0
0
19
125
1.54
0.95
1.2
1.2
—
—
—
0
0
37
279
1.35
0.93
4.4
3.9
1.24
1.23
mmol/l
1.20
32
252
19
126
1.53
0.92
1.2
1.2
—
—
—
0
0
13
78
1.68
0.92
1.6
2.1
8.18
8.04
kpa
0.14
13
78
6
30
2.01
0.87
1.5
1.5
—
—
—
0
0
16
104
1.56
0.85
1.8
1.4
263.10
306.32
ug/g
—
10
64
8
45
1.79
0.84
1.1
1.2
—
—
—
0
0
409
3954
1.21
0.82
4.3
3.7
1.39
1.28
mmol/l
2.18
386
3680
0
26
0.00
0.78
0.0
1.6
—
—
—
0
0
6
34
1.77
0.76
1.3
1.6
—
—
—
0
0
5
25
2.01
0.73
2.2
2.7
—
—
—
0
0
80
691
1.19
0.69
3.4
4.0
26.45
21.37
%
2.11
38
291
45
367
1.25
0.68
2.7
3.1
—
—
—
0
0
14
95
1.49
0.64
2.4
1.6
—
—
—
0
0
422
4114
1.19
0.63
4.8
4.1
4.75
4.78
mmol/l
0.21
403
3870
118
1061
1.15
0.63
1.7
1.6
1.43
1.41
mmol/l
0.09
100
918
25
194
1.30
0.57
1.5
1.8
5.12
3.05
mg/l
0.90
25
148
420
4103
1.17
0.55
4.7
4.0
1.47
1.49
mmol/l
0.48
398
3838
6
38
1.59
0.54
2.0
1.6
—
—
—
0
0
6
38
1.59
0.54
1.2
1.1
—
—
—
0
0
57
497
1.17
0.47
2.6
2.7
0.78
0.72
ug/l
0.27
36
295
5
32
1.57
0.42
1.2
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
2.3
—
—
—
0
0
12
89
1.36
0.38
2.4
2.5
23.76
25.05
mmol/l
0.67
12
89
40
459
0.86
0.37
1.5
1.6
—
—
—
0
0
6
45
1.34
0.34
2.5
2.5
101.50
105.09
mmol/l
—
6
45
12
93
1.30
0.30
1.2
1.2
—
—
—
0
0
51
462
1.12
0.27
4.4
4.2
30.56
31.69
%
0.31
41
303
28
243
1.16
0.27
1.3
1.3
—
—
—
0
0
37
329
1.13
0.26
1.2
1.2
54.41
162.56
iu/ml
2.76
15
140
27
235
1.16
0.26
2.5
2.3
15.49
13.27
nmol/l
0.49
21
220
9
75
1.20
0.25
1.7
1.6
—
—
—
0
0
5
40
1.25
0.22
1.2
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
13
154
0.84
0.19
1.2
1.3
199.24
244.08
miu/ml
—
7
77
12
143
0.84
0.19
1.5
1.5
—
—
—
0
0
8
71
1.13
0.16
1.4
1.9
208.38
237.80
pmol/l
—
8
65
53
562
0.94
0.14
1.3
1.8
1.31
1.43
%
0.77
47
506
24
264
0.90
0.14
1.5
2.7
29.67
45.25
u/ml
0.39
24
256
8
98
0.81
0.14
1.3
1.6
—
—
—
0
0
14
156
0.89
0.10
1.3
1.8
—
—
—
0
0
38
362
1.05
0.08
4.3
4.3
2.40
22.03
ug/l
0.99
27
294
6
70
0.86
0.07
1.3
1.5
—
—
—
0
0
8
76
1.05
0.07
1.4
1.5
—
—
—
0
0
17
159
1.07
0.05
1.3
1.4
—
—
—
0
0
20
207
0.96
0.01
1.4
1.6
—
—
—
0
0
12
122
0.98
0.00
1.2
1.5
—
—
—
0
0
12
122
0.98
0.00
1.2
1.5
—
—
—
0
0
12
122
0.98
0.00
1.2
1.5
—
—
—
0
0
12
122
0.98
0.00
1.2
1.5
—
—
—
0
0
22
222
0.99
0.00
1.2
1.0
—
—
—
0
0
13
129
1.01
0.00
1.2
1.5
—
—
—
0
0
81
812
1.00
0.00
1.5
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
65.67
—
0
6
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
1.26
—
0
9
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
5
58
0.86
-0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
0.71
—
0
7
8
84
0.95
-0.00
1.6
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_SCLERITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_SCLERITIS | 1.084 [0.86, 1.37] | 0.504 |
| Birth year | 1.001 [0.99, 1.01] | 0.834 |
During the follow-up period (1.1.1998 — 31.12.2019), 104 out of 1178 females with H7_SCLERITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_SCLERITIS | 1.021 [0.79, 1.31] | 0.872 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 90 out of 823 males with H7_SCLERITIS died.
Mortality risk
Mortality risk for people of age
years, who have H7_SCLERITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.093% | 0.155% |
| 5 | 0.755% | 1.052% |
| 10 | 1.801% | 2.761% |
| 15 | 3.691% | 5.513% |
| 20 | 6.633% | 9.676% |
Relationships between endpoints
↥Index endpoint: H7_SCLERITIS – Scleritis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data