No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2031 |
4. Check minimum number of eventsNone |
2031 |
5. Include endpointsNone |
2031 |
6. Filter based on genotype QC (FinnGen only) |
2031 |
Control definitions (FinnGen only)
- Control exclude
- H7_SCLERACORNEA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H15
- Name in latin
- Episcleritis
Similar endpoints
↥List of similar endpoints to
Episcleritis
based on the number of shared cases.
Similar with more cases:
- Scleritis and episcleritis
- Disorders of sclera, cornea, iris and ciliary body
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12330 | 7764 | 4495 |
| Only index persons | 11967 | 7599 | 4368 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.19 | 0.22 | 0.13 |
| Only index persons | 0.24 | 0.28 | 0.17 |
| Median age at first event (years) | |||
| Whole population | 46.37 | 47.31 | 44.90 |
| Only index persons | 46.22 | 47.12 | 44.66 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2031 | 1417 | 614 |
| Unadjusted period prevalence (%) | 0.42 | 0.48 | 0.27 |
| Median age at first event (years) | 48.68 | 47.74 | 50.85 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1805
- Matched controls
- 18051
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
1093.6
323.0
421
5
H15.1
ICD-10 Finland
Episcleritis
4503599627370496.0
323.0
1796
20
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
5.7
247.0
1007
3273
H15.0
ICD-10 Finland
Scleritis
+∞
166.3
157
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.5
131.6
977
4599
H57.1
ICD-10 Finland
Ocular pain
12.8
126.7
235
209
H04.10
ICD-10 Finland
Dry eye syndrome
5.8
123.9
395
836
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
10.6
103.3
210
222
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
21.8
94.7
141
70
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
202.6
93.3
96
5
S01BC03
ATC
diclofenac; ophthalmic
15.1
93.1
159
115
H20.1
ICD-10 Finland
Chronic iridocyclitis
+∞
92.5
88
*
H16.0
ICD-10 Finland
Corneal ulcer
14.1
83.3
146
112
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.4
75.6
428
1502
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.8
68.1
325
986
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
5.2
62.4
206
433
H16.9
ICD-10 Finland
Keratitis, unspecified
295.8
56.6
57
*
H02AB06
ATC
prednisolone; systemic
2.2
53.2
927
5913
F01
ICPC
Eye pain
7.9
52.7
125
169
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
4.7
51.0
186
433
F02
ICPC
Red eye
5.8
50.6
152
284
A07EC01
ATC
sulfasalazine; oral, rectal
3.8
50.2
231
668
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
3.5
50.2
260
829
M45
ICD-10 Finland
Ankylosing spondylitis
9.5
47.4
100
111
S01FA04
ATC
cyclopentolate; ophthalmic
23.2
45.1
65
29
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
22.0
45.1
66
31
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.2
40.2
232
796
R51.80
ICD-10 Finland
Headache
2.4
35.2
339
1580
S01AD03
ATC
aciclovir; ophthalmic
5.3
33.7
106
209
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.3
33.1
178
578
A02BC02
ATC
pantoprazole; systemic
1.8
32.0
1165
9013
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
3.6
30.9
150
449
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
296.5
28.9
29
*
H20
ICD-10 Finland
Iridocyclitis
39.6
28.1
35
9
S01FA02
ATC
scopolamine; ophthalmic
18.7
27.5
42
23
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
4.8
27.1
92
198
H11.3
ICD-10 Finland
Conjunctival haemorrhage
4.5
26.6
97
225
S01GX01
ATC
cromoglicic acid; ophthalmic
2.0
26.3
413
2356
L04AX01
ATC
azathioprine; systemic
3.6
25.7
122
359
H20.8
ICD-10 Finland
Other iridocyclitis
131.8
24.6
26
*
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
4.8
23.9
82
179
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.8
23.0
154
577
H02AB07
ATC
prednisone; oral
2.1
22.9
280
1434
H16.2
ICD-10 Finland
Keratoconjunctivitis
84.5
22.7
25
*
H01.0
ICD-10 Finland
Blepharitis
3.1
22.4
128
433
F29
ICPC
Eye symptom/complaint other
2.6
22.4
175
719
N02AX02
ATC
tramadol; systemic, rectal
1.7
22.3
717
5111
M25.5
ICD-10 Finland
Pain in joint
1.7
22.2
547
3605
S01ED01
ATC
timolol; ophthalmic
5.1
22.2
71
144
L04AB04
ATC
adalimumab; parenteral
5.4
22.0
67
128
M79.6
ICD-10 Finland
Pain in limb
1.7
22.0
636
4396
J01AA02
ATC
doxycycline; systemic
1.7
21.9
1397
11982
N02BE01
ATC
paracetamol; systemic, rectal
1.8
21.8
1515
13332
H10
ICD-10 Finland
Conjunctivitis
2.8
21.7
144
538
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
3.7
21.6
98
278
S01BC05
ATC
ketorolac; ophthalmic
4.3
21.6
81
194
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
21.4
830
6207
M01AH05
ATC
etoricoxib; oral
1.6
21.2
1083
8688
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
21.1
646
4521
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
15.7
21.1
34
22
M01AE02
ATC
naproxen; oral, rectal
1.6
20.7
1027
8152
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
7.8
20.4
47
62
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
4.7
20.2
70
155
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
19.8
657
4681
J01DB01
ATC
cefalexin; oral
1.7
19.6
1458
12781
J01FA10
ATC
azithromycin; systemic
1.6
19.5
1077
8716
H40.0
ICD-10 Finland
Glaucoma suspect
2.8
19.5
130
486
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
19.4
512
3421
UJF32
NOMESCO Finland
Coloscopy
1.8
19.4
423
2668
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.5
19.0
157
663
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.6
18.9
148
607
A02BC03
ATC
lansoprazole; oral
1.7
18.6
499
3344
M03BX02
ATC
tizanidine; oral
1.6
18.3
1149
9520
R03AC02
ATC
salbutamol; inhalant
1.5
17.7
930
7356
R06.0
ICD-10 Finland
Dyspnoea
1.7
17.4
384
2419
A02BC05
ATC
esomeprazole; systemic
1.6
17.4
702
5212
M13.9
ICD-10 Finland
Arthritis, unspecified
2.4
16.9
146
633
M54.5
ICD-10 Finland
Low back pain
1.6
16.9
589
4210
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
16.8
810
6251
XCK00
NOMESCO Finland
Perimetry
2.8
16.8
112
420
J01FF01
ATC
clindamycin; systemic
1.6
16.4
459
3093
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
16.3
420
2764
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
15.8
305
1835
L04AB01
ATC
etanercept; parenteral
5.7
15.7
45
81
J01FA09
ATC
clarithromycin; systemic
1.6
15.5
581
4207
P01BA02
ATC
hydroxychloroquine; oral
2.2
15.3
162
773
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
10.5
15.2
29
28
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
14.8
424
2862
J01MA02
ATC
ciprofloxacin; systemic
1.5
14.7
600
4416
XCK10
NOMESCO Finland
Photography of fundus of eye
2.2
14.3
153
732
S01XA18
ATC
ciclosporin; ophthalmic
13.5
14.2
24
18
A02BC01
ATC
omeprazole; systemic
1.6
14.2
445
3068
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.7
14.1
96
366
R01AD09
ATC
mometasone; nasal
1.5
14.1
803
6349
M01AB05
ATC
diclofenac; systemic, rectal
1.5
14.0
1170
10000
J01FA06
ATC
roxithromycin; oral
1.5
13.9
690
5291
G44.2
ICD-10 Finland
Tension-type headache
1.8
13.9
245
1430
L88
ICPC
Rheumatoid/seropositive arthritis
3.0
13.8
79
268
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.0
13.8
190
1013
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.3
13.7
127
572
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
13.6
282
1730
F03
ICPC
Eye discharge
2.5
13.6
110
463
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
13.5
441
3068
S01ED51
ATC
timolol, combinations; ophthalmic
2.7
13.5
91
342
R06AX27
ATC
desloratadine; oral
1.5
13.5
500
3586
J05AB01
ATC
aciclovir; systemic
1.6
13.5
361
2384
H19.1
ICD-10 Finland
Herpesviral keratitis and keratoconjunctivitis
141.0
13.5
14
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.2
13.3
132
612
P01AB01
ATC
metronidazole; oral, rectal
1.5
13.3
703
5450
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
13.2
397
2700
R52.9
ICD-10 Finland
Pain, unspecified
2.1
13.2
148
725
L04AA13
ATC
leflunomide; oral
3.4
13.2
63
189
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
13.1
854
6895
J01CA04
ATC
amoxicillin; systemic
1.5
13.1
1416
12684
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.6
13.1
97
388
H53.1
ICD-10 Finland
Subjective visual disturbances
2.4
13.1
109
464
R05
ICPC
Cough
1.6
13.0
371
2487
L04AA06
ATC
mycophenolic acid; systemic
4.9
13.0
42
88
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
12.6
497
3608
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
12.5
354
2370
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
130.9
12.4
13
*
SPAT1009
SPAT
Measurement of intraocular pressure
5.5
12.4
36
67
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
2.5
12.2
98
410
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
12.1
669
5206
M01AH01
ATC
celecoxib; oral (coxibs)
1.7
12.1
296
1904
AA1AD
NOMESCO Finland
CT of head and brain
1.6
11.9
321
2116
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
7.6
11.9
27
36
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
11.9
284
1814
H19.3*M35.0
ICD-10 Finland
Keratoconjunctivitis sicca
47.0
11.9
14
*
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
4.9
11.7
37
76
M01AC06
ATC
meloxicam; systemic, rectal
1.5
11.7
612
4700
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.2
11.6
114
528
N03AX12
ATC
gabapentin; oral
1.7
11.6
253
1571
H18.8
ICD-10 Finland
Other specified disorders of cornea
65.4
11.6
13
*
H25.1
ICD-10 Finland
Senile nuclear cataract
1.7
11.6
237
1448
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
4.3
11.6
42
100
C07AB07
ATC
bisoprolol; oral
1.4
11.5
628
4858
R03DC03
ATC
montelukast; oral
1.7
11.5
284
1831
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
120.7
11.4
12
*
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
11.4
1237
10877
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
4.2
11.3
42
102
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
11.3
621
4804
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.0
11.3
155
825
S01GX09
ATC
olopatadine; ophthalmic
3.2
11.3
58
185
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
11.3
201
1175
XCH00
NOMESCO Finland
Eye pressure measurement
3.1
11.3
61
202
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.1
11.3
132
661
J02AC01
ATC
fluconazole; systemic
1.4
11.2
751
6034
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
11.2
955
8020
K50.8
ICD-10 Finland
Other Crohn disease
4.1
11.1
42
104
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
5.1
11.1
34
68
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
11.0
601
4638
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
11.0
423
3037
S01GX08
ATC
ketotifen; ophthalmic
2.7
11.0
74
281
K08.80
ICD-10 Finland
Toothache NOS
2.0
11.0
147
776
H26.3
ICD-10 Finland
Drug-induced cataract
9.3
11.0
22
24
R06AE07
ATC
cetirizine; oral
1.4
11.0
751
6049
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
10.9
269
1732
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
10.8
1118
9687
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
10.8
307
2052
N03AX16
ATC
pregabalin; oral
1.5
10.8
371
2596
Z01.2
ICD-10 Finland
Dental examination
1.4
10.7
693
5515
A07EC02
ATC
mesalazine; oral, rectal
2.2
10.7
107
499
UJF30
NOMESCO Finland
Ileoscopy through colon
1.9
10.7
160
880
R42
ICD-10 Finland
Dizziness and giddiness
1.6
10.7
316
2132
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.0
10.7
138
719
ZXA00
NOMESCO Finland
Right side
1.5
10.6
388
2753
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.5
10.6
381
2688
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
2.7
10.6
71
270
S01EC01
ATC
acetazolamide; systemic
4.6
10.4
35
78
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.3
10.3
92
409
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
10.2
444
3266
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.6
10.1
263
1713
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
10.0
293
1970
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.0
9.8
130
685
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
9.8
141
764
E0000UV
ATC
NA
1.4
9.8
623
4924
R20.2
ICD-10 Finland
Paraesthesia of skin
2.0
9.8
121
621
SPAT1263
SPAT
Sampling
1.4
9.7
669
5362
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
9.7
281
1881
M79.1
ICD-10 Finland
Myalgia
1.7
9.7
211
1309
M01AX17
ATC
nimesulide; oral
1.5
9.7
366
2609
D07AC13
ATC
mometasone; topical
1.5
9.7
451
3360
L04AD01
ATC
ciclosporin; systemic
3.6
9.6
42
119
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
5.1
9.6
29
58
R01AD12
ATC
fluticasone furoate; nasal
1.4
9.6
522
4007
R05FA02
ATC
opium derivatives and expectorants; systemic
1.4
9.5
638
5081
-1
NOMESCO Finland
NA
1.4
9.5
566
4411
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.9
9.5
139
759
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.7
9.5
183
1094
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
9.5
271
1809
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
9.4
534
4128
H10.2
ICD-10 Finland
Other acute conjunctivitis
4.3
9.4
33
77
H16.1
ICD-10 Finland
Other superficial keratitis without conjunctivitis
30.2
9.4
12
*
H19.2*B02.3
ICD-10 Finland
Keratitis and keratoconjunctivitis (interstitial) in zoster
+∞
9.4
9
*
36903
ICD-8 Finland
Other inflammatory diseases of eye, Episcleritis
+∞
9.4
9
*
H18.4
ICD-10 Finland
Corneal degeneration
+∞
9.4
9
*
A02BA02
ATC
ranitidine; systemic
1.6
9.4
289
1967
H10.4
ICD-10 Finland
Chronic conjunctivitis
5.9
9.4
25
43
R03BA05
ATC
fluticasone; inhalant
1.6
9.3
292
1997
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.9
9.2
131
708
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
3.0
9.2
51
173
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
5.7
9.2
25
44
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
9.2
268
1798
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
3.6
9.1
40
114
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.2
9.1
88
406
K50.0
ICD-10 Finland
Crohn disease of small intestine
3.7
9.0
38
105
S01EA03
ATC
apraclonidine; ophthalmic
10.1
9.0
17
17
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
9.0
155
895
R01AD08
ATC
fluticasone; nasal
1.4
9.0
487
3725
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
7.5
8.9
20
27
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.7
8.9
193
1196
L04AB06
ATC
golimumab; parenteral
5.3
8.9
26
50
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
8.9
352
2531
Z3231
NOMESCO Finland
Registered nurse
1.4
8.8
408
3028
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
8.8
263
1771
H02AB04
ATC
methylprednisolone; systemic
1.6
8.8
226
1464
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
8.8
410
3045
R00.2
ICD-10 Finland
Palpitations
1.9
8.8
129
707
R05
ICD-10 Finland
Cough
1.5
8.8
300
2087
H26.2
ICD-10 Finland
Complicated cataract
4.7
8.7
28
60
M54.6
ICD-10 Finland
Pain in thoracic spine
1.9
8.7
119
634
J05AB11
ATC
valaciclovir; oral
1.6
8.7
209
1333
ZXA05
NOMESCO Finland
Left side
1.5
8.6
355
2572
R74
ICPC
Upper respiratory infection acute
1.4
8.6
496
3837
R50.9
ICD-10 Finland
Fever, unspecified
1.6
8.5
203
1291
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
27.6
8.5
11
*
114
Kela drug reimbursment
Glaucoma
2.1
8.5
92
449
XQ800
NOMESCO Finland
Prick test
1.8
8.4
132
740
H16.8
ICD-10 Finland
Other keratitis
90.5
8.4
9
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
8.4
137
776
R53
ICD-10 Finland
Malaise and fatigue
1.5
8.4
296
2073
S18
ICPC
Laceration/cut
1.4
8.4
594
4754
R21
ICPC
Throat symptom/complaint
1.5
8.4
335
2412
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
12.8
8.4
14
11
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
2.7
8.3
54
204
ZXA10
NOMESCO Finland
Bilateral
1.5
8.3
257
1748
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.4
8.2
69
296
K02.1
ICD-10 Finland
Caries of dentine
1.3
8.2
966
8359
L01AA01
ATC
cyclophosphamide; systemic
14.5
8.2
13
9
L03
ICPC
Low back symptom/complaint
1.4
8.1
367
2705
J20
ICD-10 Finland
Acute bronchitis
1.8
8.1
149
878
H26.4
ICD-10 Finland
After-cataract
2.0
8.1
94
472
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
8.1
152
902
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
8.1
990
8611
A03
ICPC
Fever
1.5
8.1
255
1743
KMAK
NOMESCO Finland
NA
1.3
8.1
901
7732
D07AD01
ATC
clobetasol; topical
1.6
8.1
236
1584
R02
ICPC
Shortness of breath/dyspnoea
1.7
8.1
170
1045
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
9.0
8.0
16
18
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
8.0
849
7223
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
8.0
347
2541
J01DA01
ATC
[U] cefalexin; systemic
1.3
8.0
1051
9236
D07AC01
ATC
betamethasone; topical
1.4
8.0
518
4083
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
7.9
727
6047
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.4
7.9
67
290
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
7.8
269
1874
L17
ICPC
Foot/toe symptom/complaint
1.4
7.8
363
2690
N06AX21
ATC
duloxetine; oral
1.6
7.8
185
1179
CG2S4
NOMESCO Finland
Photography of cornea
45.2
7.7
9
*
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
7.7
476
3714
H30.2
ICD-10 Finland
Posterior cyclitis
25.1
7.6
10
*
G43.9
ICD-10 Finland
Migraine, unspecified
1.9
7.5
108
588
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.8
7.5
137
807
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.3
7.5
36
112
G44.8
ICD-10 Finland
Other specified headache syndromes
3.6
7.5
31
86
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
7.4
136
801
F73
ICPC
Eye infection/inflammation other
3.4
7.4
34
102
J01EA01
ATC
trimethoprim; systemic
1.4
7.4
382
2884
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
7.4
164
1023
R11
ICD-10 Finland
Nausea and vomiting
1.9
7.4
112
619
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
7.4
207
1375
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
3.6
7.4
31
87
G47.3
ICD-10 Finland
Sleep apnoea
1.4
7.3
314
2290
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
+∞
7.3
7
*
36400
ICD-8 Finland
Iritis, Iridocyclitis acuta
+∞
7.3
7
*
PAW37
NOMESCO Finland
Biopsy of temporal artery
6.9
7.3
17
25
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
7.3
433
3351
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
7.3
195
1278
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
7.3
213
1430
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.8
7.3
117
664
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
5.2
7.2
21
41
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
1.6
7.2
173
1101
H66.9
ICD-10 Finland
Otitis media, unspecified
2.0
7.2
91
473
R52.2
ICD-10 Finland
Other chronic pain
2.4
7.2
58
249
TAB00
NOMESCO Finland
Lumbar puncture
2.1
7.2
78
383
S01EC04
ATC
brinzolamide; ophthalmic
2.9
7.2
41
142
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.3
7.1
63
282
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
5.6
7.1
19
34
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.9
7.0
102
559
XF404
NOMESCO Finland
Ambulatory ECG
1.8
7.0
120
693
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
3.0
7.0
37
124
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
2.5
7.0
50
201
A07EA06
ATC
budesonide; oral, local oral
2.3
7.0
62
279
D06BX01
ATC
metronidazole; topical
1.6
6.9
178
1158
R06AX22
ATC
ebastine; oral
1.5
6.9
285
2060
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
2.4
6.9
56
241
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
6.9
156
981
WZC30
NOMESCO Finland
Teaching
1.6
6.9
188
1241
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
6.9
102
561
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
6.9
389
2982
L71.9
ICD-10 Finland
Rosacea, unspecified
2.6
6.9
46
179
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
2.7
6.8
42
155
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.9
6.8
98
533
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.7
6.8
139
847
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.8
622
5140
G50.0
ICD-10 Finland
Trigeminal neuralgia
3.1
6.8
35
115
S01AA13
ATC
fusidic acid; ophthalmic
2.5
6.8
49
199
J01FA15
ATC
telithromycin; oral
1.6
6.8
167
1074
SPAT1260
SPAT
Consultation of another employee
1.5
6.7
260
1851
NH3EA
NOMESCO Finland
Feet X-ray examination with load
3.0
6.7
36
122
S01ED02
ATC
betaxolol; ophthalmic
7.2
6.7
15
21
J35.0
ICD-10 Finland
Chronic tonsillitis
1.9
6.7
93
501
F13
ICPC
Eye sensation abnormal
2.7
6.7
43
161
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
22.6
6.7
9
*
S01AX11
ATC
[U] ofloxacin; ophthalmic
2.4
6.7
51
213
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.6
6.7
187
1241
R03BA01
ATC
beclometasone; inhalant
1.5
6.6
213
1457
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.8
6.6
102
568
J01DA06
ATC
[U] cefuroxime; systemic
1.5
6.6
241
1696
K50.1
ICD-10 Finland
Crohn disease of large intestine
3.5
6.6
29
85
J01MA14
ATC
moxifloxacin; systemic
1.7
6.6
130
784
R51
ICD-10 Finland
Headache
1.9
6.6
88
467
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.9
6.6
86
453
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
6.5
301
2220
M31.3
ICD-10 Finland
Wegener granulomatosis
10.1
6.5
12
12
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
10.1
6.5
12
12
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.5
6.5
197
1331
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
6.5
575
4724
M01CB01
ATC
sodium aurothiomalate; parenteral
3.6
6.5
27
76
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
6.5
153
974
M01AH02
ATC
rofecoxib; oral
1.6
6.4
180
1193
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
3.2
6.4
31
98
G44.0
ICD-10 Finland
Cluster headache syndrome
3.5
6.4
27
77
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.6
6.4
178
1179
WX110
NOMESCO Finland
Local anesthesy
1.3
6.3
1150
10394
E000007
ATC
NA
1.9
6.3
90
490
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
4.2
6.3
22
53
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
11.1
6.3
11
10
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.1
6.3
69
341
H22.1
ICD-10 Finland
Iridocyclitis in other diseases classified elsewhere
+∞
6.3
6
*
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
6.2
433
3425
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
3.2
6.2
30
95
C07AA05
ATC
propranolol; systemic
1.4
6.2
311
2328
S01EE01
ATC
latanoprost; ophthalmic
2.1
6.2
64
308
WX290
NOMESCO Finland
Other blockade of nerve
1.3
6.2
737
6293
R06AE09
ATC
levocetirizine; oral
1.5
6.2
233
1650
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.3
6.2
430
3400
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
6.2
102
583
A01
ICPC
Pain general/multiple sites
1.8
6.1
107
624
J01DC02
ATC
cefuroxime; systemic
1.8
6.1
94
524
WZA90
NOMESCO Finland
Other doctors statement
1.4
6.1
351
2692
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
1.8
6.1
92
512
T15.1
ICD-10 Finland
Foreign body in conjunctival sac
3.6
6.1
25
70
4AB02
NOMESCO Finland
NA
8.6
6.1
12
14
AA1ED
NOMESCO Finland
Trauma CT of head and neck
10.1
6.0
11
11
X58
ICD-10 Finland
Exposure to other specified factors
1.5
6.0
196
1347
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
6.0
1580
15009
Mortality – FinRegistry
↥Association
Association between endpoint H7_EPISCLERITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_EPISCLERITIS | 0.976 [0.86, 1.11] | 0.716 |
| Birth year | 0.995 [0.99, 1.0] | 0.202 |
During the follow-up period (1.1.1998 — 31.12.2019), 401 out of 6850 females with H7_EPISCLERITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_EPISCLERITIS | 0.891 [0.78, 1.02] | 0.088 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 333 out of 3989 males with H7_EPISCLERITIS died.
Mortality risk
Mortality risk for people of age
years, who have H7_EPISCLERITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.079% | 0.105% |
| 5 | 0.549% | 0.867% |
| 10 | 1.368% | 2.199% |
| 15 | 2.618% | 4.184% |
| 20 | 4.691% | 7.167% |
Relationships between endpoints
↥Index endpoint: H7_EPISCLERITIS – Episcleritis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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