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Melanoma in situ, other sites/unspecified

DOID Endpoint Browser

CD2_INSITU_MELANOMA_NOS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

117

4. Check minimum number of events

None

117

5. Include endpoints

None

117

6. Filter based on genotype QC (FinnGen only)

116

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 116 62 54
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 67.35 64.15 71.02

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
117
Matched controls
1170
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D03.9
ICD-10 Finland
Melanoma in situ, unspecified
4515.1
120.3
95
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
20.3
49.8
45
35
D03.8
ICD-10 Finland
Melanoma in situ of other sites
+∞
27.1
25
*
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
47.5
24.4
29
8
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
238.7
20.2
20
*
R23.8
ICD-10 Finland
Other and unspecified skin changes
5.9
19.9
52
139
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.8
19.4
38
77
L57.0
ICD-10 Finland
Actinic keratosis
6.2
18.4
41
94
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
7.0
18.1
33
62
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
6.5
14.8
28
54
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
17.2
12.3
19
13
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
9.0
10.8
23
31
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
+∞
10.6
10
*
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
44.1
10.2
12
*
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
9.8
10.1
20
24
D03.5
ICD-10 Finland
Melanoma in situ of trunk
60.1
9.8
11
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
9.7
8.7
17
20
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
96.7
8.5
9
*
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
48.3
7.8
9
*
TQW99
NOMESCO Finland
Other minor procedure on skin
6.7
7.6
19
33
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
4.7
7.6
19
46
C43.99
ICD-10 Finland
Unspecified localization of malignant melanoma of the skin other or unspecified histology
85.3
7.5
8
*
C43
ICD-10 Finland
Malignant melanoma of skin
85.3
7.5
8
*
SPAT1153
SPAT
Removal of sutures
2.9
7.5
56
279
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
7.5
7.4
17
26
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
32.2
7.3
9
*
S18
ICPC
Laceration/cut
2.9
7.1
73
428
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
42.6
6.8
8
*
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
24.1
6.8
9
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.4
6.6
28
100
ZXC50
NOMESCO Finland
Cryotherapy
6.5
6.1
15
26

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
53
126
6.86
23.49
1.7
1.3
—
—
—
0
0
92
387
7.45
21.18
4.4
2.2
—
—
—
0
0
31
92
4.22
9.73
1.5
1.3
—
—
—
0
0
7
9
8.18
3.61
1.1
1.2
—
—
—
0
0
90
697
2.26
3.45
5.2
3.8
14.95
14.92
pmol/l
0.04
79
622
69
489
2.00
3.30
7.5
6.9
1.23
1.21
mmol/l
1.70
54
410
65
452
1.99
3.27
6.3
6.3
1.22
1.21
mmol/l
1.19
59
406
66
464
1.97
3.19
3.3
3.9
0.00
0.00
estimate
-0.00
17
99
67
474
1.97
3.17
3.4
3.9
0.00
0.00
estimate
-0.00
16
86
48
303
1.99
3.16
3.6
2.9
6.75
7.34
mmol/l
0.50
39
248
20
88
2.54
3.15
3.4
1.9
551.90
400.93
nmol/l
0.50
20
80
22
102
2.42
3.11
1.9
1.7
—
—
—
0
0
66
467
1.95
3.10
4.3
5.2
0.00
0.00
estimate
-0.00
17
90
74
557
1.89
2.76
9.5
9.1
3.85
4.20
e9/l
0.66
64
490
46
298
1.90
2.74
3.7
3.0
37.50
261.71
mg/l
0.53
32
191
49
326
1.87
2.68
2.9
2.2
—
—
—
0
0
48
319
1.86
2.62
4.6
3.6
9.90
6.99
mg/mmol
0.17
31
200
16
71
2.45
2.47
3.4
3.5
—
—
—
0
0
5
9
5.74
2.23
1.0
1.1
—
—
—
0
0
16
75
2.31
2.20
1.1
2.6
—
—
—
0
0
45
308
1.75
2.15
3.5
3.1
—
—
—
0
0
110
997
2.73
2.13
23.2
18.1
86.75
81.25
umol/l
0.41
110
997
57
418
1.71
2.13
3.7
4.0
30.99
46.83
ng/l
0.81
38
306
60
448
1.70
2.08
7.2
6.0
—
—
—
0
0
106
938
2.38
2.06
20.6
15.6
22.18
25.01
mg/l
0.50
94
761
112
1030
3.04
2.06
29.9
22.8
39.30
39.91
%
0.47
106
966
37
244
1.76
1.99
2.7
2.1
3.16
3.12
mg/l
0.04
32
213
64
493
1.66
1.93
6.4
5.7
0.16
0.18
e9/l
0.55
55
437
38
255
1.73
1.92
3.9
4.3
0.00
0.00
estimate
-0.00
16
87
43
300
1.69
1.88
4.4
4.4
—
—
—
0
0
50
365
1.65
1.84
3.0
3.8
—
5.75
—
0
24
62
478
1.63
1.83
6.1
5.5
0.04
0.04
e9/l
0.33
53
416
62
479
1.63
1.81
6.1
5.4
0.61
0.59
e9/l
0.18
53
418
37
251
1.69
1.79
3.7
3.8
—
—
—
0
0
20
112
1.95
1.78
1.1
1.3
—
—
—
0
0
101
891
1.98
1.76
4.9
4.2
1.30
1.26
mmol/l
0.23
94
798
49
362
1.61
1.69
3.0
3.5
2.35
2.35
mmol/l
0.01
42
315
107
968
2.23
1.66
20.7
14.6
—
—
—
0
0
62
489
1.57
1.60
6.1
5.6
1.82
1.80
e9/l
0.07
55
437
104
936
2.00
1.56
5.4
4.7
4.50
4.53
mmol/l
0.10
97
856
79
662
1.60
1.54
5.6
4.3
—
—
—
0
0
103
927
1.93
1.50
5.4
4.7
1.48
1.48
mmol/l
0.02
96
837
90
782
1.65
1.47
9.6
7.2
74.28
80.11
u/l
1.29
83
727
10
46
2.28
1.44
1.6
1.3
—
—
—
0
0
14
75
1.98
1.41
5.6
4.3
—
—
—
0
0
50
384
1.53
1.40
3.8
2.7
178.34
125.43
ug/l
0.63
45
347
80
680
1.56
1.40
5.1
4.2
—
—
—
0
0
84
722
1.58
1.39
4.8
4.4
12.46
13.08
mm/h
0.17
79
661
97
865
1.71
1.36
6.3
4.7
2.15
1.92
mu/l
0.35
88
771
103
938
1.82
1.28
5.8
4.9
6.35
6.03
mmol/l
0.80
94
847
57
457
1.48
1.28
4.6
4.4
35.73
35.14
g/l
0.39
52
423
6
26
2.38
1.20
1.7
2.1
—
—
—
0
0
104
958
1.77
1.12
5.9
5.3
2.62
2.62
mmol/l
0.02
97
869
30
216
1.52
1.11
2.5
3.7
—
—
—
0
0
5
21
2.44
1.10
2.8
2.9
—
—
—
0
0
16
98
1.73
1.10
6.0
3.8
—
—
—
0
0
9
46
2.03
1.06
6.8
2.3
—
—
—
0
0
9
47
1.99
1.05
2.3
1.8
—
—
—
0
0
31
229
1.48
1.01
1.5
1.8
409.83
460.77
pmol/l
0.50
24
196
40
312
1.43
0.99
4.3
3.2
15.72
245.32
e6/l
0.57
34
239
40
313
1.42
0.97
6.4
4.2
7.40
7.40
ph
0.05
13
60
0
32
0.00
0.96
0.0
1.1
—
—
—
0
0
36
278
1.43
0.93
4.3
3.1
1.80
0.67
e6/l
0.30
30
205
45
362
1.40
0.93
5.5
5.0
2.54
2.06
ug/l
0.39
38
316
54
448
1.38
0.93
7.0
5.4
2.69
2.69
%
0.00
49
418
54
448
1.38
0.93
7.5
5.7
8.98
8.66
%
0.19
48
419
6
28
2.20
0.93
2.5
2.0
—
—
—
0
0
13
79
1.73
0.92
4.6
3.6
0.71
0.86
%
—
7
29
97
894
1.50
0.85
7.3
6.2
42.33
40.79
mmol/mol
0.72
88
827
35
274
1.40
0.84
3.8
2.7
348.97
4183.00
umol/l
1.01
29
225
0
24
0.00
0.80
0.0
1.3
—
0.25
—
0
24
0
25
0.00
0.80
0.0
1.7
—
253.22
—
0
13
50
418
1.34
0.79
14.2
9.9
0.01
0.00
e9/l
0.48
39
332
0
26
0.00
0.79
0.0
1.2
—
—
—
0
0
54
458
1.33
0.77
7.3
5.6
26.75
26.24
%
0.11
48
429
9
54
1.72
0.76
2.2
2.6
1.38
1.62
g/l
—
9
46
51
430
1.33
0.76
7.2
5.3
0.57
0.67
%
0.65
46
399
43
356
1.33
0.72
4.9
3.8
88.89
68.44
e6/l
0.21
36
257
34
272
1.35
0.71
4.3
2.9
—
—
—
0
0
16
112
1.50
0.68
1.1
1.3
—
—
—
0
0
52
450
1.28
0.61
7.1
5.4
56.60
58.49
%
0.42
46
422
11
73
1.56
0.58
5.2
3.7
0.60
0.13
%
—
5
23
17
125
1.42
0.57
2.8
3.2
1.91
1.84
%
0.07
17
110
29
235
1.31
0.55
1.6
1.3
—
—
—
0
0
6
40
1.53
0.52
1.5
5.1
—
—
—
0
0
19
147
1.35
0.49
1.5
1.2
—
—
—
0
0
11
77
1.47
0.47
2.5
2.4
—
—
—
0
0
85
795
1.25
0.46
23.3
19.0
15.06
15.25
%
0.11
80
781
17
131
1.35
0.45
3.2
7.3
105.35
103.71
mmol/l
0.49
17
131
33
280
1.25
0.44
1.8
1.6
1.19
1.36
mmol/l
0.76
22
241
8
57
1.43
0.43
1.6
1.5
—
—
—
0
0
8
59
1.38
0.42
2.6
2.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
56
507
1.20
0.40
20.9
14.3
1.18
1.31
inr
0.49
19
145
9
66
1.39
0.39
1.6
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
5.7
—
—
—
0
0
5
36
1.41
0.38
4.6
3.8
—
—
—
0
0
25
212
1.23
0.34
4.4
3.1
0.98
0.77
ug/l
0.42
14
134
37
327
1.19
0.33
3.3
3.3
—
—
—
0
0
29
253
1.19
0.30
4.7
3.8
86.17
87.27
%
0.11
29
248
7
57
1.24
0.29
1.3
1.6
0.70
1.10
g/l
—
7
48
8
65
1.25
0.28
1.5
2.1
10.05
10.64
g/l
—
8
55
11
86
1.31
0.27
2.6
3.2
121.91
205.09
ng/l
0.64
11
75
8
67
1.21
0.27
1.5
1.3
—
—
—
0
0
31
276
1.17
0.26
1.5
1.6
24.30
21.12
nmol/l
0.28
23
228
18
152
1.22
0.25
1.7
1.8
—
—
—
0
0
17
199
0.83
0.24
1.2
1.2
0.64
0.86
u/ml
—
5
64
24
211
1.17
0.23
2.3
1.7
1273.53
1166.36
nmol/l
0.22
15
156
5
40
1.26
0.22
2.8
3.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
0.97
—
0
11
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
3.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
3.5
—
4.59
—
0
13
31
281
1.14
0.20
7.9
4.3
—
—
—
0
0
14
118
1.21
0.20
1.8
2.9
10.57
8.80
umol/l
0.11
14
101
45
420
1.12
0.19
2.4
2.1
97.35
92.44
pmol/l
0.20
22
205
7
86
0.80
0.15
1.7
1.3
—
—
—
0
0
18
160
1.15
0.15
4.3
2.9
1.14
2.84
e6/l
—
10
85
12
105
1.16
0.11
1.8
1.5
—
—
—
0
0
13
115
1.15
0.11
1.6
1.8
—
—
—
0
0
16
145
1.12
0.10
1.1
1.3
1.51
16.87
u/ml
—
7
63
11
124
0.88
0.09
1.9
7.5
5.27
5.08
kpa
0.38
11
118
11
124
0.88
0.09
1.4
4.6
2.88
43.06
ug/l
—
6
103
11
124
0.88
0.09
1.9
7.5
13.70
11.76
kpa
0.44
11
119
5
48
1.04
0.09
2.0
2.8
0.54
0.71
%
—
5
48
6
54
1.12
0.09
1.3
1.4
—
—
—
0
0
6
57
1.06
0.08
3.3
3.8
—
—
—
0
0
8
78
1.03
0.07
1.9
1.4
—
—
—
0
0
10
92
1.10
0.03
1.9
1.7
—
—
—
0
0
25
259
0.96
0.03
7.4
7.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
20.34
—
0
9
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
72.80
—
0
5
0
5
0.00
0.00
0.0
2.4
—
78.60
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
5
55
0.91
-0.00
1.8
1.3
—
—
—
0
0
7
76
0.92
-0.00
1.3
4.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
185.54
—
0
7
8
85
0.94
-0.00
1.8
9.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
2.0
2.7
0.92
1.20
%
—
5
50
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.5
—
10.30
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
7.15
—
0
6

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_INSITU_MELANOMA_NOS – Melanoma in situ, other sites/unspecified

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).