Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system, including Hilmo

C3_SPINAL_CORD_CRANIAL_AND_OTHER_CNS_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C72
  • Hospital discharge: ICD-9 192
  • Hospital discharge: ICD-8 192
  • Cause of death: ICD-10 C72
  • Cause of death: ICD-9 192
  • Cause of death: ICD-8 192
  • Cause of death: excluded ICD-9 1921|1923|1928
  • Cancer registry: Topography ICD-O-3 C72
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

294

4. Check minimum number of events

None

294

5. Include endpoints

None

294

6. Filter based on genotype QC (FinnGen only)

283

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 283 144 139
Unadjusted period prevalence (%) 0.06 0.05 0.06
Median age at first event (years) 52.98 47.89 58.26

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
294
Matched controls
2940
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02AB02
ATC
dexamethasone; systemic
78.5
139.4
76
13
130
Kela drug reimbursment
Malignant tumour
+∞
65.1
60
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
10.2
55.8
72
91
C72.00
ICD-10 Finland
Malignant tumor of the spinal cord without histology
+∞
51.6
48
*
C72.1
ICD-10 Finland
Malignant neoplasm: Cauda equina
+∞
47.2
44
*
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
484.0
43.4
42
*
C72.9
ICD-10 Finland
Malignant neoplasm: Central nervous system, unspecified
+∞
42.8
40
*
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
+∞
40.6
38
*
A04AA01
ATC
ondansetron; systemic, rectal
14.1
35.5
34
27
9391/3-C72.0
ICD-O-3
Ependymoma, NOS, of spinal cord
+∞
35.1
33
*
A03FA01
ATC
metoclopramide; systemic, rectal
5.5
34.5
82
193
C72.09
ICD-10 Finland
Malignant tumor of the spinal cord other histology
+∞
34.0
32
*
XX3DW
NOMESCO Finland
Time consuming IT work
9.9
32.7
40
46
WF002
NOMESCO Finland
Radical radiotherapy
64.0
25.5
29
5
JN4BD
NOMESCO Finland
Extensive body CT
7.5
25.3
39
59
A04AA02
ATC
granisetron; systemic, transdermal
272.2
25.1
25
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
142.1
25.0
26
*
C72.2
ICD-10 Finland
Malignant neoplasm: Olfactory nerve
+∞
24.3
23
*
C72.01
ICD-10 Finland
Malignant tumor of the spinal cord grade II glioma
+∞
23.2
22
*
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
44.0
23.1
28
7
Z51.5
ICD-10 Finland
Palliative care
9.8
22.4
27
30
C72.3
ICD-10 Finland
Malignant neoplasm: Optic nerve
+∞
22.2
21
*
JN4AD
NOMESCO Finland
Body CT examination
6.9
22.0
36
58
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
9.7
21.5
26
29
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
21.1
20
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
213.8
19.8
20
*
D43.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Spinal cord
+∞
19.0
18
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.3
18.7
97
386
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
17.9
17
*
L01AX03
ATC
temozolomide; systemic
+∞
17.9
17
*
D33.4
ICD-10 Finland
Benign neoplasm: Spinal cord
+∞
17.9
17
*
N02AA05
ATC
oxycodone; systemic
3.8
17.3
62
194
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
29.6
16.8
22
8
C61
ICD-10 Finland
Malignant neoplasm of prostate
179.8
16.7
17
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
5.3
16.6
36
76
XKC03
NOMESCO Finland
Water cystometry
7.7
15.9
23
32
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.4
15.7
68
240
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
13.4
15.7
27
22
XKD06
NOMESCO Finland
Physiologic investigation of micturition
7.2
15.5
24
36
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
6.5
15.4
26
43
115
Kela drug reimbursment
Breast cancer
+∞
14.7
14
*
D33.41
ICD-10 Finland
Myxopapillary epndymoma of the spinal cord (grade I)
+∞
14.7
14
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.9
14.2
33
74
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
18.7
14.0
21
12
D33.40
ICD-10 Finland
Benign glioma of the spinal cord (grade I)
+∞
13.6
13
*
C72.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of brain and other parts of central nervous system
+∞
13.6
13
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
13.6
13
*
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
19.4
13.6
20
11
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
14.8
13.5
22
16
M03BX01
ATC
baclofen; systemic
13.1
12.8
22
18
L28
ICPC
Limited function/disability (L)
2.9
12.8
73
300
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
+∞
12.6
12
*
1922A
ICD-9 Finland
Malignant neoplasm of other and unspecified parts of nervous system, Spinal cord
+∞
12.6
12
*
9522/3-C30.0
ICD-O-3
Olfactory neuroblastoma of nasal cavity
+∞
12.6
12
*
D33.43
ICD-10 Finland
Spinal cord
+∞
12.6
12
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
135.6
12.5
13
*
WZC00
NOMESCO Finland
Treatment plan or consultation
2.6
12.3
99
485
R4110
NOMESCO Finland
Physiotherapy
2.6
12.0
91
432
N18
ICPC
Paralysis/weakness
10.3
12.0
23
24
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
67.7
11.7
13
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
11.5
11
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
11.5
11
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
11.5
11
*
C72.0
ICD-10 Finland
Malignant neoplasm: Spinal cord
+∞
11.5
11
*
G82.2
ICD-10 Finland
Paraplegia, unspecified
26.2
11.3
15
6
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
9.4
11.0
22
25
R1250
NOMESCO Finland
Evaluation of functional capability
11.2
11.0
20
19
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
13.6
10.8
18
14
N03AX16
ATC
[U] pregabalin
2.6
10.6
79
369
UKC02
NOMESCO Finland
Cystoscopy
3.0
10.6
53
201
L03AA02
ATC
filgrastim; parenteral
+∞
10.5
10
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
10.5
10
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
10.5
10
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.0
10.4
50
186
R4120
NOMESCO Finland
Occupational therapy
4.1
10.0
29
77
ZXE30
NOMESCO Finland
More than five and less than seven hours
7.8
9.9
22
30
Z2446
NOMESCO Finland
Social worker
3.8
9.8
31
88
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
56.9
9.7
11
*
H02AB09
ATC
hydrocortisone; systemic
10.6
9.7
18
18
TKC20
NOMESCO Finland
Catheterisation of bladder
3.7
9.6
32
94
PJA12
NOMESCO Finland
Sentinel node biopsy
103.2
9.5
10
*
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
103.2
9.5
10
*
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
9.4
9
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
9.4
9
*
Q85.01
ICD-10 Finland
Neurofibromatosis, type 2
+∞
9.4
9
*
2312
FHL
Extirpation or destruction
+∞
9.4
9
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
9.4
9
*
ZX050
NOMESCO Finland
Stereotactic radiotherapy
+∞
9.4
9
*
N03AE01
ATC
clonazepam; systemic
3.8
9.3
30
86
ZXE10
NOMESCO Finland
More than one and less than three hours
2.2
9.3
111
634
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
12.0
9.2
16
14
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
16.2
9.1
14
9
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.5
9.1
23
55
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
19.3
9.0
13
7
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.7
9.0
21
47
Z3231
NOMESCO Finland
Registered nurse
2.3
9.0
87
455
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
9.1
8.9
18
21
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.2
8.9
38
131
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.0
8.9
43
160
H47.2
ICD-10 Finland
Optic atrophy
51.6
8.7
10
*
H53.4
ICD-10 Finland
Visual field defects
9.4
8.7
17
19
TPX10
NOMESCO Finland
Implantation of vascular injection port
9.4
8.7
17
19
ZXC95
NOMESCO Finland
Use of surgical navigator
16.9
8.6
13
8
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
16.9
8.6
13
8
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.3
8.6
33
107
D33.30
ICD-10 Finland
Acoustic neuroma
20.8
8.5
12
6
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
92.6
8.5
9
*
D32.1
ICD-10 Finland
Benign neoplasm: Spinal meninges
92.6
8.5
9
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
8.4
8
*
C72.4
ICD-10 Finland
Malignant neoplasm: Acoustic nerve
+∞
8.4
8
*
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
+∞
8.4
8
*
116
Kela drug reimbursment
Prostate cancer
+∞
8.4
8
*
C71.20
ICD-10 Finland
Malignant tumor in temporal lobe without histology
+∞
8.4
8
*
1929X
ICD-9 Finland
Malignant neoplasm of other and unspecified parts of nervous system, Nervous system, part unspecified
+∞
8.4
8
*
C30.0
ICD-10 Finland
Malignant neoplasm: Nasal cavity
+∞
8.4
8
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
8.4
8
*
J01MA12
ATC
levofloxacin; systemic
2.5
8.3
61
281
L72.1
ICD-10 Finland
Trichilemmal cyst
3.8
8.2
26
74
L03AA13
ATC
pegfilgrastim; parenteral
34.4
8.1
10
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
34.4
8.1
10
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
10.5
8.1
15
15
B01AB05
ATC
enoxaparin; parenteral
2.2
8.0
91
506
R33
ICD-10 Finland
Retention of urine
3.2
7.9
33
112
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
46.2
7.8
9
*
N03AX14
ATC
levetiracetam; systemic
7.0
7.7
18
27
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.4
7.7
58
270
L02AE02
ATC
leuprorelin; implant, parenteral
25.8
7.6
10
*
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.9
7.5
22
59
AA1AD
NOMESCO Finland
CT of head and brain
2.1
7.5
87
486
ZXD05
NOMESCO Finland
Urgent procedure
2.1
7.4
96
557
WW500
NOMESCO Finland
Blood transfusion
8.7
7.4
15
18
2311
FHL
Resection
+∞
7.3
7
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
7.3
7
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
7.3
7
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
7.3
7
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
7.3
7
*
G82.1
ICD-10 Finland
Spastic paraplegia
+∞
7.3
7
*
A79
ICPC
Malignancy NOS
+∞
7.3
7
*
N76
ICPC
Neoplasm nervous system unspecified
+∞
7.3
7
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
7.3
7
*
1920A
ICD-9 Finland
Malignant neoplasm of other and unspecified parts of nervous system, Cranial nerves
+∞
7.3
7
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
7.3
7
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
7.3
7
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
7.3
7
*
19251
ICD-8 Finland
Malignant neoplasm of other part of nervous system, Sympathetic nervous system
+∞
7.3
7
*
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
+∞
7.3
7
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
7.3
7
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
7.3
113
700
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
20.6
7.2
10
5
N31.8
ICD-10 Finland
Other neuromuscular dysfunction of bladder
20.6
7.2
10
5
ZX120
NOMESCO Finland
Intravenous
3.5
7.0
25
77
TPH07
NOMESCO Finland
Cathetrisation of artery
2.9
7.0
33
121
XKD00
NOMESCO Finland
Uroflowmetry
2.6
7.0
44
188
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
6.8
63
319
E23.00
ICD-10 Finland
Panhypopituitarism
41.0
6.8
8
*
HAB40
NOMESCO Finland
Wedge excision of mammary gland
41.0
6.8
8
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
6.7
36
142
N03AB02
ATC
phenytoin; systemic
9.0
6.6
13
15
2252A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Cerebral meninges
71.3
6.5
7
*
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.2
6.4
17
42
J01EA01
ATC
trimethoprim; systemic
2.0
6.4
79
447
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
6.2
6.4
16
27
WX704
NOMESCO Finland
Intubation
3.3
6.3
24
77
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
18.5
6.3
9
5
XCK00
NOMESCO Finland
Perimetry
3.1
6.3
26
88
9380/3-C71.9
ICD-O-3
Glioma, malignant of brain, NOS
+∞
6.3
6
*
1921A
ICD-9 Finland
Malignant neoplasm of other and unspecified parts of nervous system, Cerebral meninges
+∞
6.3
6
*
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
+∞
6.3
6
*
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
6.3
6
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
6.3
6
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
6.3
6
*
D33.7
ICD-10 Finland
Benign neoplasm: Other specified parts of central nervous system
+∞
6.3
6
*
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
+∞
6.3
6
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
6.3
6
*
H03AA01
ATC
levothyroxine sodium; systemic
2.1
6.3
68
367
SPAT1229
SPAT
Assessment of need for aid
3.0
6.3
29
105
G91.0
ICD-10 Finland
Communicating hydrocephalus
27.3
6.3
8
*
G91.1
ICD-10 Finland
Obstructive hydrocephalus
27.3
6.3
8
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
6.1
59
304

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
57
53
13.10
54.76
1.5
1.5
—
—
—
0
0
64
210
3.62
16.64
5.7
9.5
1.52
1.43
mmol/l
0.07
51
170
25
45
5.98
13.61
2.2
1.1
—
—
—
0
0
101
490
2.62
12.88
3.6
3.3
92.55
90.41
%
0.31
91
478
165
1014
2.43
12.49
8.1
5.9
1.20
1.22
mmol/l
3.27
146
874
20
15
14.21
12.13
2.4
1.1
—
—
—
0
0
114
608
2.43
11.69
2.4
1.9
—
—
—
0
0
24
48
5.36
11.68
2.3
1.1
10.13
4.29
e6/l
0.42
16
38
24
48
5.36
11.68
2.4
1.2
1819.65
332.00
e6/l
0.42
17
39
146
903
2.23
10.24
7.1
5.8
1.20
1.22
mmol/l
1.98
141
813
119
679
2.26
10.15
2.5
1.6
—
—
—
0
0
54
226
2.70
8.97
7.8
6.3
104.59
104.25
mmol/l
0.19
54
226
93
500
2.26
8.97
5.0
3.7
—
—
—
0
0
17
23
7.77
7.79
1.8
1.1
—
—
—
0
0
40
160
2.74
7.21
7.6
8.4
—
—
—
0
0
107
656
1.99
7.06
4.8
2.0
2.34
2.36
mmol/l
0.78
98
549
98
594
1.97
6.61
4.9
2.9
—
—
—
0
0
162
1165
1.87
6.43
14.6
6.0
3.79
4.24
e9/l
2.16
140
1009
45
208
2.37
6.01
5.9
3.5
2.52
2.07
mmol/l
0.52
40
174
173
1290
1.83
5.92
6.4
4.3
6.56
6.66
mmol/l
0.27
164
1197
10
9
11.45
5.84
2.2
1.4
2.96
1.81
mmol/l
—
10
9
13
23
5.86
5.12
1.4
1.3
—
—
—
0
0
138
995
1.73
5.01
8.8
5.4
25.90
28.20
%
1.41
129
927
135
973
1.72
4.87
9.0
5.5
9.00
8.48
%
0.95
126
903
136
989
1.70
4.70
8.6
5.2
58.04
57.08
%
0.42
127
924
145
1073
1.69
4.70
8.7
5.1
1.62
1.87
e9/l
3.14
128
938
130
935
1.70
4.68
8.7
5.2
0.67
0.68
%
0.03
120
864
142
1046
1.69
4.67
8.7
5.0
0.55
0.58
e9/l
0.79
121
894
86
551
1.79
4.66
4.0
2.7
0.51
0.46
e6/l
0.09
70
399
133
965
1.69
4.61
9.5
5.5
—
—
—
0
0
133
966
1.69
4.59
8.7
5.2
2.54
2.85
%
1.11
123
895
142
1050
1.68
4.58
8.7
5.0
0.04
0.04
e9/l
0.22
120
899
67
401
1.87
4.51
4.2
2.5
549.00
548.58
mosm/kgh2o
0.01
61
331
133
978
1.66
4.30
16.8
14.4
1.20
1.31
inr
0.52
29
282
143
1083
1.62
4.04
9.2
5.2
0.15
0.19
e9/l
3.26
124
943
27
122
2.34
3.80
4.0
8.4
—
—
—
0
0
125
929
1.60
3.74
12.8
7.1
0.01
0.00
e9/l
0.55
102
738
190
2199
0.62
3.69
4.5
4.5
5.87
5.96
mmol/l
0.56
170
2012
22
92
2.50
3.66
4.8
4.5
—
—
—
0
0
195
2232
0.62
3.42
4.1
4.4
4.53
4.66
mmol/l
1.04
170
2081
7
10
7.14
3.38
1.0
1.1
—
—
—
0
0
6
7
8.72
3.27
1.3
1.0
—
—
—
0
0
201
2276
0.63
3.21
4.4
4.9
2.70
2.76
mmol/l
0.45
181
2111
86
604
1.60
3.17
4.0
2.8
62.01
159.09
e6/l
0.41
68
449
63
409
1.69
3.16
3.0
2.2
6.53
7.59
e6/l
0.16
56
360
194
2210
0.64
3.12
4.1
4.4
1.40
1.47
mmol/l
1.99
170
2053
78
538
1.61
3.09
3.9
2.6
—
—
—
0
0
19
82
2.41
2.98
7.9
15.6
—
—
—
0
0
26
129
2.11
2.96
3.5
4.5
1.67
0.60
%
—
9
34
42
247
1.82
2.96
2.1
1.7
—
—
—
0
0
81
576
1.56
2.80
4.6
2.7
7.40
7.40
ph
0.11
13
84
42
252
1.78
2.78
2.0
2.2
23.85
24.51
%
0.06
36
221
72
499
1.59
2.78
12.0
4.4
—
—
—
0
0
188
1599
1.49
2.69
10.8
5.1
81.34
76.11
u/l
1.05
182
1471
24
124
2.02
2.48
3.6
4.6
0.43
0.07
%
—
7
28
23
117
2.05
2.48
3.8
4.6
1.43
0.21
%
—
7
29
8
21
3.89
2.48
1.3
1.1
—
—
—
0
0
11
38
2.97
2.44
3.9
1.4
—
—
—
0
0
6
12
5.08
2.41
3.7
1.9
532.67
786.17
e6/l
—
6
12
6
12
5.08
2.41
1.7
1.2
—
—
—
0
0
175
1487
1.44
2.38
6.2
3.8
—
—
—
0
0
8
22
3.71
2.38
2.3
1.3
—
—
—
0
0
5
8
6.33
2.38
1.2
1.0
—
—
—
0
0
163
1368
1.43
2.37
6.9
4.0
—
2749.00
—
0
19
48
316
1.62
2.28
3.8
2.7
2.05
2.82
e6/l
0.33
30
153
189
2121
0.70
2.26
3.7
4.0
1.30
1.28
mmol/l
0.13
167
1955
95
728
1.45
2.24
4.5
3.3
108.81
109.05
e6/l
0.00
74
487
47
310
1.61
2.21
2.1
2.1
12.48
13.96
umol/l
0.56
42
280
26
145
1.87
2.19
1.3
1.4
—
—
—
0
0
55
381
1.55
2.11
4.2
2.0
2.45
2.44
mmol/l
0.55
50
318
42
273
1.63
2.10
1.9
2.1
2.36
2.30
g/l
0.29
37
252
13
56
2.38
2.08
1.2
1.1
—
—
—
0
0
6
15
4.06
2.05
1.5
1.1
—
—
—
0
0
32
197
1.70
1.96
3.8
4.2
—
—
—
0
0
41
594
0.64
1.90
1.6
1.7
1.38
1.39
mmol/l
0.03
36
503
36
233
1.62
1.84
1.4
1.5
—
—
—
0
0
26
154
1.76
1.83
3.2
2.2
10.43
14.48
nmol/l
1.51
21
144
26
157
1.72
1.72
1.2
1.3
—
33.98
—
0
12
41
280
1.54
1.69
2.4
2.1
—
—
—
0
0
26
163
1.65
1.52
2.2
2.2
73.74
65.46
e9/l
0.38
20
131
5
17
2.97
1.36
1.4
1.2
—
—
—
0
0
12
61
2.01
1.34
4.8
1.7
—
—
—
0
0
40
287
1.46
1.32
1.6
1.6
—
—
—
0
0
18
108
1.71
1.25
6.6
2.9
—
—
—
0
0
7
142
0.48
1.24
1.4
1.4
—
—
—
0
0
53
678
0.73
1.24
2.8
3.1
44.84
323.81
mg/l
1.08
35
436
192
2080
0.78
1.22
5.0
5.8
38.58
39.92
mmol/mol
1.42
177
1938
59
734
0.75
1.13
3.4
2.9
7.31
7.64
mmol/l
0.22
53
620
11
58
1.93
1.13
3.2
2.6
—
—
—
0
0
5
21
2.40
1.09
2.2
1.7
—
—
—
0
0
64
515
1.31
1.08
2.1
2.0
3.89
3.04
mg/l
1.03
54
435
58
715
0.76
1.04
3.6
3.6
6.96
6.14
mg/mmol
0.16
38
448
7
34
2.08
1.03
2.6
2.1
—
—
—
0
0
7
34
2.08
1.03
2.6
2.1
107.29
105.38
mmol/l
—
7
34
7
34
2.08
1.03
2.6
2.1
3.90
4.14
mmol/l
—
7
34
67
808
0.78
1.01
2.9
2.9
—
—
—
0
0
13
211
0.60
1.01
1.5
1.3
—
—
—
0
0
79
661
1.27
0.99
2.2
2.2
55.64
62.76
u/l
0.46
69
612
47
368
1.33
0.96
1.6
1.8
—
—
—
0
0
23
163
1.45
0.85
1.4
1.1
—
—
—
0
0
244
2536
0.78
0.83
30.9
16.8
4.45
4.54
e12/l
1.85
239
2452
100
876
1.21
0.82
4.2
3.5
637.49
87.81
ng/l
0.43
72
598
101
886
1.21
0.82
4.7
3.2
5.92
5.87
ph
—
6
65
244
2534
0.78
0.80
31.5
16.8
39.65
40.44
%
1.10
230
2357
244
2534
0.78
0.80
30.8
16.8
244.74
249.08
e9/l
0.45
239
2459
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
6
33
1.83
0.79
1.7
1.4
—
—
—
0
0
0
25
0.00
0.79
0.0
1.3
—
5.83
—
0
19
0
25
0.00
0.79
0.0
1.3
—
0.35
—
0
19
0
25
0.00
0.79
0.0
1.3
—
2.63
—
0
19
0
25
0.00
0.79
0.0
1.3
—
—
—
0
0
65
548
1.24
0.77
2.3
2.5
330.13
7533.27
umol/l
2.49
53
478
32
247
1.33
0.74
1.7
1.5
—
—
—
0
0
226
2361
0.82
0.73
19.3
10.8
—
—
—
0
0
60
507
1.23
0.70
1.6
1.5
22.13
20.28
nmol/l
0.37
51
435
5
28
1.80
0.66
1.2
1.1
—
—
—
0
0
6
102
0.58
0.63
1.0
1.1
—
6.20
—
0
5
5
30
1.68
0.61
1.6
1.5
—
—
—
0
0
5
30
1.68
0.61
2.6
2.8
64.80
59.67
%
—
5
30
0
22
0.00
0.59
0.0
1.1
—
193.50
—
0
22
233
2412
0.84
0.57
14.1
8.4
26.81
26.53
u/l
0.08
227
2314
6
36
1.68
0.57
1.7
1.3
—
—
—
0
0
33
402
0.80
0.56
2.6
2.4
0.42
0.76
ug/l
5.57
22
251
117
1072
1.15
0.54
5.4
3.3
0.00
0.01
estimate
0.50
26
178
9
62
1.47
0.53
12.8
3.5
—
—
—
0
0
6
39
1.55
0.53
15.0
3.1
—
—
—
0
0
61
532
1.19
0.53
1.2
1.4
—
—
—
0
0
63
715
0.85
0.52
4.4
3.6
3.75
1.89
ug/l
0.52
56
638
42
492
0.83
0.50
5.8
3.6
1.01
1.02
kg/l
—
5
72
7
45
1.57
0.49
3.7
2.1
—
—
—
0
0
118
1092
1.13
0.46
5.5
3.3
0.00
0.00
estimate
-0.00
25
154
10
138
0.71
0.41
3.0
2.3
—
—
—
0
0
20
159
1.28
0.41
8.1
3.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
581614.67
—
0
9
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
62
554
1.15
0.41
5.6
3.6
0.00
0.00
estimate
-0.00
25
157
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
39
450
0.85
0.40
2.5
1.3
1.99
2.46
g/l
1.09
23
268
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
36
418
0.84
0.40
4.1
3.7
31.97
254.34
ng/l
2.46
31
316
0
19
0.00
0.39
0.0
3.1
—
—
—
0
0
9
69
1.31
0.37
2.0
1.4
—
—
—
0
0
115
1077
1.11
0.36
7.6
4.6
0.00
0.00
estimate
-0.00
25
162
52
465
1.14
0.34
1.7
1.7
202273154.52
440.81
pmol/l
0.49
44
396
22
183
1.22
0.33
1.5
1.7
—
—
—
0
0
11
83
1.34
0.32
6.6
7.8
—
—
—
0
0
55
497
1.13
0.32
4.6
3.4
—
—
—
0
0
15
120
1.26
0.30
3.5
5.0
—
—
—
0
0
16
195
0.81
0.30
1.2
1.2
—
—
—
0
0
65
597
1.11
0.29
5.7
3.0
—
—
—
0
0
18
215
0.83
0.28
1.2
1.5
—
—
—
0
0
159
1529
1.09
0.27
3.6
3.6
—
—
—
0
0
9
72
1.26
0.26
1.4
1.5
—
—
—
0
0
17
142
1.21
0.25
4.1
1.4
—
—
—
0
0
22
189
1.18
0.25
1.2
1.4
—
—
—
0
0
6
81
0.74
0.24
1.0
1.2
—
—
—
0
0
204
2090
0.92
0.23
5.4
4.3
1.94
1.91
mu/l
0.17
187
1909
13
157
0.82
0.23
1.5
1.4
—
—
—
0
0
5
39
1.29
0.23
7.0
2.0
—
—
—
0
0
5
40
1.25
0.22
1.4
1.1
0.15
2.04
u/ml
—
5
26
5
42
1.19
0.21
3.4
3.4
0.54
0.83
nmol/l
—
5
34
0
11
0.00
0.21
0.0
1.1
—
151.45
—
0
11
0
11
0.00
0.21
0.0
1.1
—
109.95
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
0.65
—
0
5
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
11
133
0.82
0.20
1.3
1.2
—
—
—
0
0
5
69
0.72
0.17
8.0
1.4
—
—
—
0
0
97
935
1.06
0.14
2.5
2.5
130.00
122.63
ug/l
0.10
89
868
175
1714
1.05
0.14
5.0
3.6
14.95
14.74
pmol/l
0.49
164
1545
63
660
0.94
0.13
5.2
3.6
—
—
—
0
0
18
162
1.12
0.12
3.6
4.0
57.38
74.99
ng/l
0.86
12
145
168
1648
1.05
0.12
4.1
4.0
14.92
11.60
mm/h
1.24
153
1499
41
433
0.94
0.11
2.0
1.9
0.85
1.12
mg/l
0.85
29
325
151
1483
1.04
0.09
3.4
3.1
64.13
46.24
u/l
0.77
144
1397
22
237
0.92
0.09
2.2
1.7
—
—
—
0
0
6
54
1.11
0.09
3.8
1.7
257.00
235.83
pmol/l
—
6
48
5
61
0.82
0.08
7.2
1.8
—
—
—
0
0
7
64
1.10
0.08
1.1
1.2
—
—
—
0
0
10
112
0.89
0.07
1.4
1.3
—
—
—
0
0
7
80
0.87
0.07
6.4
1.4
—
—
—
0
0
9
86
1.05
0.07
1.1
1.1
—
—
—
0
0
16
149
1.08
0.05
5.8
2.7
4.27
4.60
e9/l
0.15
11
114
25
262
0.95
0.05
2.3
2.4
87.44
101.55
ug/g
0.17
18
213
38
392
0.96
0.04
1.6
1.3
18.05
34.72
iu/ml
1.46
13
118
225
2263
0.98
0.04
21.8
11.5
24.01
21.85
mg/l
0.40
199
1720
88
891
0.98
0.02
2.1
2.0
90.72
94.00
pmol/l
0.29
49
441
28
289
0.97
0.02
1.6
1.4
626.67
488.42
titre
—
6
76
10
98
1.02
0.00
1.0
1.1
—
—
—
0
0
18
179
1.01
0.00
3.9
3.0
—
—
—
0
0
41
411
1.00
0.00
1.9
1.7
1294.59
1167.91
nmol/l
0.34
34
312
29
287
1.01
0.00
1.6
1.2
—
—
—
0
0
10
104
0.96
0.00
4.0
2.7
0.57
0.21
e6/l
—
10
99
11
114
0.96
0.00
2.8
2.3
—
—
—
0
0
10
104
0.96
0.00
1.4
1.8
—
—
—
0
0
37
374
0.99
0.00
1.4
1.2
29.05
9.64
u/ml
0.37
11
139
7
75
0.93
0.00
6.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
21
210
1.00
-0.00
1.3
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
31.82
—
0
5
0
7
0.00
-0.00
0.0
4.7
—
—
—
0
0
7
79
0.88
-0.00
6.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
2.10
—
0
7
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
79
0.88
-0.00
6.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
38.5
—
158.67
—
0
6
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.2
—
—
—
0
0
6
60
1.00
-0.00
1.7
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
11.00
—
0
6
0
6
0.00
-0.00
0.0
9.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
11.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
78
0.89
-0.00
6.0
1.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_SPINAL_CORD_CRANIAL_AND_OTHER_CNS_WIDE – Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system, including Hilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).