Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system

C3_SPINAL_CORD_CRANIAL_AND_OTHER_CNS

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Cause of death: ICD-10 — C72 Cause of death: ICD-9 — 192 Cause of death: ICD-8 — 192 Cause of death: excluded ICD-9 — 1921\|1923\|1928 Cancer registry: Topography ICD-O-3 — C72 Cancer registry: Morphology ICD-O-3 — ANY Cancer registry: Behaviour codes — 3 2 out of 7 registries used, show all original rules.	67
4. Check minimum number of events None	67
5. Include endpoints None	67
6. Filter based on genotype QC (FinnGen only)	67

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF9

NAME	C3_SPINAL_CORD_CRANIAL_AND_OTHER_CNS
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	C72
COD_ICD_9	192
COD_ICD_8	192
COD_ICD_10_EXCL
COD_ICD_9_EXCL	1921\|1923\|1928
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO	C72
CANC_TOPO_EXCL
CANC_MORPH	ANY
CANC_MORPH_EXCL
CANC_BEHAV	3

Similar endpoints

↥

List of similar endpoints to Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	67	33	34
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	53.09	49.81	56.27

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
62: Matched controls
620

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

9391/3-C72.0

ICD-O-3

Ependymoma, NOS, of spinal cord

+∞

32.1

ABB10

NOMESCO Finland

Resection of lesion of spinal canal

381.6

25.7

ABB00

NOMESCO Finland

Excision of lesion of spinal canal

155.0

21.1

C72.00

ICD-10 Finland

Malignant tumor of the spinal cord without histology

+∞

18.7

C72.09

ICD-10 Finland

Malignant tumor of the spinal cord other histology

+∞

15.2

C72.01

ICD-10 Finland

Malignant tumor of the spinal cord grade II glioma

+∞

15.2

D43.4

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Spinal cord

+∞

11.8

NA7DG

NOMESCO Finland

Spine and spinal cord very extensive MRI examination with high intensity magnet

73.0

11.1

M03BX01

ATC

baclofen; systemic

48.6

10.4

NA2CG

NOMESCO Finland

Thoracal spine extensive MRI examination with high intensity magnet

+∞

9.6

D33.40

ICD-10 Finland

Benign glioma of the spinal cord (grade I)

+∞

9.6

NA1CG

NOMESCO Finland

Cervical spine extensive MRI examination with high intensity magnet

43.7

9.4

D33.43

ICD-10 Finland

Spinal cord

+∞

8.5

WX408

NOMESCO Finland

General anesthesy, balanced

5.5

8.5

NA3CG

NOMESCO Finland

Lumbar spine extensive MRI examination with high intensity magnet

16.1

7.8

D33.4

ICD-10 Finland

Benign neoplasm: Spinal cord

+∞

7.4

XKD06

NOMESCO Finland

Physiologic investigation of micturition

23.4

7.4

H02AB02

ATC

dexamethasone; systemic

7.1

6.9

AA1BG

NOMESCO Finland

Standard MRI examination of brain with high intensity magnet

8.2

6.9

L28

ICPC

Limited function/disability (L)

5.6

6.8

N03AX16

ATC

pregabalin; oral

4.6

6.7

NA2BG

NOMESCO Finland

Thoracal spine MRI examination with high intensity magnet

16.7

6.7

ZXM10

NOMESCO Finland

Intraoperative use of conventional X-ray imaging

9.3

6.5

D33.41

ICD-10 Finland

Myxopapillary epndymoma of the spinal cord (grade I)

+∞

6.3

NA7CG

NOMESCO Finland

Spine and spinal cord extensive MRI examination with high intensity magnet

17.2

6.1

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(4035726)

7.13

11.73

1.4

1.3

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

23.08

7.38

2.4

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

5.95

7.34

3.4

8.9

24.8

24.9

mmol/l

0.03

(3003396) Base excess in Arterial blood by calculation

4.49

6.63

5.3

9.9

1.7

1.4

mmol/l

0.17

(3044640) Blood type and Crossmatch panel - Blood

177

3.23

5.29

2.8

2.0

—

(3012320) Pathologist interpretation of Cerebral spinal fluid tests

+∞

5.27

1.2

0.0

—

(3016018) Differential panel - Cerebral spinal fluid

15.38

4.68

3.6

1.2

—

(3044290) Cell count panel - Cerebral spinal fluid

8.89

4.19

3.4

2.0

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

234

2.76

3.96

6.5

6.3

1.2

mmol/l

0.64

216

(3023410) Appearance of Cerebral spinal fluid

12.98

3.84

1.5

2.8

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

129

2.66

3.48

2.6

1.9

—

(42870588) Differential panel, method unspecified - Blood

182

2.45

3.17

7.0

5.2

—

(40760888) Immunoglobulin light chains.free panel - Serum

8.09

3.12

6.3

4.8

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

256

2.40

3.00

7.1

6.6

1.2

mmol/l

0.84

221

(3000991) Gas panel - Venous blood

3.12

2.91

3.5

9.9

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

247

2.24

2.64

4.0

3.7

—

(3023368) Bacteria identified in Blood by Culture

137

2.32

2.60

6.4

4.0

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

7.60

2.59

1.2

1.9

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

4.47

2.43

1.9

1.4

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

4.47

2.43

1.9

1.4

—

(3026008) Bacteria identified in Urine by Culture

142

2.21

2.36

5.6

2.7

—

(3032080) INR in Blood by Coagulation assay

212

2.10

2.27

7.3

7.7

1.1

1.2

inr

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

4.59

2.20

1.3

2.0

—

(3014007) Fractional oxyhemoglobin in Arterial blood

2.90

1.95

5.9

12.9

95.4

94.8

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

2.28

1.95

2.6

2.4

0.7

3.6

e6/l

—

(3020891) Body temperature

3.55

1.79

4.2

5.9

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.79

1.72

7.4

2.3

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.13

1.68

2.3

0.3

1.0

e6/l

—

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

3.77

1.64

3.2

1.4

781.0

496.8

mg/l

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.38

1.48

1.3

1.8

—

(40768804) Tissue Pathology biopsy report

220

1.76

1.42

3.1

2.0

—

(36304419) Bacteria [Presence] in Urine

158

1.81

1.41

3.3

2.7

—

(3022621) pH of Urine by Test strip

0.00

1.39

0.0

2.4

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

1.39

0.0

1.5

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

2.14

1.38

4.8

10.0

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.06

1.35

1.3

1.8

—

(1761868) Lipid panel - Serum or Plasma

212

0.52

1.28

2.5

2.4

—

(3049717) Cytology report of Urine Cyto stain

2.76

1.24

4.2

2.7

—

(3000492) Spirometry study

2.13

1.16

1.1

1.3

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.86

1.16

1.9

1.6

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

2.49

1.11

1.4

3.4

1.5

1.2

—

(3012544) pH of Venous blood

2.10

1.09

2.2

3.3

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

2.37

1.05

1.8

3.8

25.2

mmol/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

198

1.61

1.03

3.4

2.9

—

(3042936) Bacteria identified in Isolate by Culture

1.83

1.00

1.8

1.9

—

(3019060) Gas panel - Arterial blood

2.25

0.94

4.2

5.8

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.17

0.92

3.3

8.1

—

(3021589) Normoblasts [#/volume] in Blood

250

1.54

0.91

13.4

8.9

0.0

e9/l

0.50

198

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

185

1.56

0.90

4.2

4.0

18.3

44.0

ng/l

0.93

126

(3013115) Eosinophils [#/volume] in Blood

290

1.52

0.88

8.6

6.2

0.1

0.2

e9/l

3.60

256

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.80

0.85

2.1

1.5

—

(40758558) Short blood count panel - Blood

152

1.56

0.83

14.2

7.3

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.81

0.0

1.5

—

(3000330) Specific gravity of Urine by Test strip

0.00

0.81

0.0

3.0

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.81

0.0

1.6

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

288

1.45

0.73

8.3

5.9

9.5

11.0

umol/l

0.86

274

(3019225) pH of Specimen

1.70

0.69

5.0

2.9

—

(40761536) Microorganisms panel - Urine sediment

1.70

0.69

12.4

3.8

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

1.58

0.68

4.4

2.9

2.5

mmol/l

0.00

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.69

0.66

2.2

1.4

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.69

0.66

2.2

1.5

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.72

0.62

1.6

1.2

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.61

0.62

4.9

3.0

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.54

0.61

2.0

1.4

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.61

0.0

1.5

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.61

0.0

1.5

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.61

0.0

1.5

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

0.00

0.61

0.0

1.7

—

226.5

—

(40768443) Skin Pathology biopsy report

0.00

0.61

0.0

1.1

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.61

0.0

1.5

—

(3018418) pH of Serum or Plasma

162

1.43

0.60

4.4

4.2

7.4

—

(3037467) Urinalysis macro (dipstick) panel - Urine

367

1.39

0.58

6.0

4.0

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.68

0.57

1.3

—

(3031040) Bacteria [#/volume] in Urine by Automated count

368

1.38

0.56

8.3

4.0

—

78.7

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.48

0.50

1.4

1.8

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.58

0.50

2.4

2.5

344.1

387.8

nmol/l

—

(3044889) 12 lead EKG panel

382

1.35

0.50

3.2

3.6

—

(3027945) Reticulocytes/100 erythrocytes in Blood

1.49

0.45

2.1

1.6

2.0

1.7

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

569

1.52

0.43

21.4

14.5

4.0

mmol/l

0.09

553

(3019550) Sodium [Moles/volume] in Serum or Plasma

566

1.57

0.43

21.7

14.6

139.6

139.7

mmol/l

0.16

548

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.38

0.42

1.5

2.0

—

(40768797) Stomach Pathology biopsy report

1.48

0.42

2.0

1.2

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.42

0.0

1.2

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.41

0.0

1.7

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.41

0.0

1.4

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.41

0.0

1.4

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.41

0.0

1.5

—

(40768793) Breast Pathology biopsy report

0.00

0.41

0.0

1.3

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.41

0.0

1.5

—

(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood

0.00

0.41

0.0

1.4

—

0.1

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.41

0.0

1.4

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.40

0.0

1.1

—

(3029937) Albumin [Presence] in Urine by Test strip

136

1.34

0.38

7.6

4.0

0.0

estimate

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

432

1.29

0.37

9.9

6.9

78.0

75.1

u/l

0.30

401

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

130

0.73

0.33

1.0

1.3

—

1.0

—

(3010813) Leukocytes [#/volume] in Blood

616

0.75

0.31

31.6

19.6

6.5

6.6

e9/l

0.12

601

(3000963) Hemoglobin [Mass/volume] in Blood

616

0.75

0.31

31.7

19.6

132.1

135.5

g/l

0.94

607

(3024731) MCV [Entitic volume]

616

0.75

0.31

31.3

19.5

90.7

90.9

0.11

608

(3026361) Erythrocytes [#/volume] in Blood

616

0.75

0.31

31.5

19.5

4.4

4.5

e12/l

0.53

602

(3035941) MCH [Entitic mass]

616

0.75

0.31

31.3

19.4

30.1

30.3

0.27

608

(3007461) Platelets [#/volume] in Blood

615

0.77

0.31

31.3

19.6

238.6

248.2

e9/l

0.41

603

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

150

1.27

0.30

4.1

4.6

16.0

21.8

—

(3013512) EKG study

141

1.28

0.30

3.0

3.4

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

189

1.24

0.29

1.9

85.8

97.2

pmol/l

—

104

(3002256) Pathology report gross observation

1.31

0.29

1.5

1.3

—

(3041096) Erythrocytes [Presence] in Urine by Automated

147

0.78

0.27

8.2

3.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

0.73

0.24

2.1

1.4

—

(40761535) Cells panel - Urine sediment

1.21

0.22

4.8

3.7

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

0.21

0.0

2.5

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.6

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.1

—

(40768800) Prostate Pathology biopsy report

0.00

0.21

0.0

1.4

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.21

0.0

1.4

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.2

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.21

0.0

4.2

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.21

0.0

1.8

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.3

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.21

0.0

1.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

347

0.85

0.21

3.2

3.3

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.21

0.0

1.5

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.20

0.0

1.3

—

(3003694) ABO and Rh group [Type] in Blood

158

1.19

0.19

1.3

1.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.74

0.18

2.0

1.9

—

(3012516) Albumin [Mass/volume] in Urine

131

1.19

0.16

2.1

3.3

22.9

63.2

mg/l

—

(3021601) Nitrite [Presence] in Urine by Test strip

268

0.89

0.12

6.5

4.9

0.0

estimate

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

586

1.23

0.07

23.0

15.3

66.9

76.8

umol/l

3.90

586

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

373

0.92

0.07

3.1

2.6

47.9

39.4

u/l

0.33

354

(3011397) Hemoglobin [Presence] in Urine by Test strip

131

0.90

0.06

4.3

3.4

—

(3020682) Albumin/Creatinine [Ratio] in Urine

139

1.10

0.06

2.5

4.0

2.6

8.5

mg/mmol

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

120

1.10

0.05

1.5

1.9

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

200

0.93

0.04

7.0

3.8

—

(3015736) pH of Urine

212

1.06

0.02

4.2

3.3

—

(3035350) Ketones [Presence] in Urine by Test strip

268

0.95

0.02

6.0

3.6

0.0

estimate

—

(3009542) Hematocrit [Volume Fraction] of Blood

504

1.05

0.00

21.4

14.7

40.3

39.9

0.16

381

(40760892) CBC W Ordered Manual Differential panel - Blood

128

1.02

0.00

6.4

5.1

—

(3009261) Glucose [Presence] in Urine by Test strip

273

0.98

0.00

5.9

3.6

0.0

estimate

—

(40761511) CBC panel - Blood by Automated count

571

0.99

0.00

16.3

11.5

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.0

1.1

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3022145) Colonoscopy Study observation

0.86

0.00

1.0

1.4

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.0

3.1

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.00

0.0

1.3

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.2

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.0

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.87

0.00

1.3

1.6

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.0

4.2

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.0

1.1

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.3

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

2.3

—

3.2

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.1

—

(3011648) Oxygen content in Venous blood

0.00

0.0

2.6

—

11.7

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.9

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.0

1.4

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.2

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.9

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.1

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

0.8

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.0

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

0.0

1.3

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.0

3.8

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.7

—

(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.0

1.7

—

(4024509)

0.00

0.0

1.3

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

14.0

—

(40760848) Basement membrane zone BP180 Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.3

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.0

1.9

—

3.2

—

(40768441) Liver Pathology biopsy report

0.00

0.0

1.0

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.0

—

(4062490)

0.00

0.0

1.0

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.0

1.6

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.2

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.0

2.8

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.4

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

0.0

2.0

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.3

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.0

1.1

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.2

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.85

0.00

2.0

1.8

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

(3000494) Fungus identified in Specimen by Culture

1.02

0.00

1.8

1.5

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: C3_SPINAL_CORD_CRANIAL_AND_OTHER_CNS – Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system (C3_SPINAL_CORD_CRANIAL_AND_OTHER_CNS)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints