Otitis media: Inflammation of the anatomical structures of the middle ear, which is most often caused by an infectious process. Symptoms include erythema and edema of the tympanic membrane, pain, and possibly fever.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
5457 |
4. Check minimum number of eventsNone |
5457 |
5. Include endpointsNone |
5457 |
6. Filter based on genotype QC (FinnGen only) |
5457 |
Control definitions (FinnGen only)
- Control exclude
- H8_MIDDLEMASTOID
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H66
- Name in latin
- Otitis media non specificata
Similar endpoints
↥List of similar endpoints to
Otitis media, unspecified
based on the number of shared cases.
Similar with more cases:
- Suppurative and unspecified otitis media
- Diseases of middle ear and mastoid
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 149321 | 66988 | 82178 |
| Only index persons | 106058 | 48151 | 57907 |
| Unadjusted period prevalence (%) | |||
| Whole population | 2.12 | 1.92 | 2.30 |
| Only index persons | 2.01 | 1.77 | 2.21 |
| Median age at first event (years) | |||
| Whole population | 2.63 | 2.92 | 2.32 |
| Only index persons | 3.24 | 3.79 | 2.78 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 5457 | 3433 | 2024 |
| Unadjusted period prevalence (%) | 1.07 | 1.17 | 0.89 |
| Median age at first event (years) | 15.78 | 15.90 | 15.57 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 4432
- Matched controls
- 41859
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
111.5
323.0
873
92
EMB30
NOMESCO Finland
Adenotomy
9.3
323.0
765
919
H65.3
ICD-10 Finland
Chronic mucoid otitis media
366.9
323.0
628
19
H66.0
ICD-10 Finland
Acute suppurative otitis media
10.8
323.0
1273
1507
UDC00
NOMESCO Finland
Ear microscopy
9.1
323.0
814
1012
38199
ICD-8 Finland
Otitis media without mention of mastoiditis, Unspecified
+∞
323.0
414
*
H66.9
ICD-10 Finland
Otitis media, unspecified
323.1
323.0
4035
1278
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
241.1
318.3
331
14
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
21.9
275.2
418
198
H65.2
ICD-10 Finland
Chronic serous otitis media
266.5
255.8
265
10
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
63.1
232.0
276
44
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.1
190.7
852
2290
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.5
183.1
2807
16997
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.5
169.0
1846
9158
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
66.2
154.2
182
27
H71
ICD-10 Finland
Cholesteatoma of middle ear
299.5
147.2
152
5
J01FA10
ATC
azithromycin; systemic
2.2
129.4
3123
21611
J01CA04
ATC
amoxicillin; systemic
3.0
124.9
4028
32032
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
120.8
118
*
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
108.7
120.7
134
12
DCD00
NOMESCO Finland
Myringoplasty
1133.5
117.8
117
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
4.0
117.3
515
1322
H65.0
ICD-10 Finland
Acute serous otitis media
10.9
109.1
218
197
H01
ICPC
Ear pain/earache
2.7
105.2
873
3536
DFF00
NOMESCO Finland
Pure tone audiometry
4.3
103.1
412
964
J35.2
ICD-10 Finland
Hypertrophy of adenoids
4.5
101.9
395
897
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
29.0
98.7
137
46
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
98.2
96
*
4122
FHL
Tympanostomy (tympanic tube)
33.5
97.8
131
38
J21.9
ICD-10 Finland
Acute bronchiolitis, unspecified
5.9
93.0
279
475
DC1AD
NOMESCO Finland
Temporalbone CT
21.4
87.2
132
60
H60.3
ICD-10 Finland
Other infective otitis externa
8.0
87.1
208
257
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
31.9
82.8
112
34
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
79.7
78
*
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
+∞
77.7
76
*
H74.1
ICD-10 Finland
Adhesive middle ear disease
+∞
72.6
71
*
H92.0
ICD-10 Finland
Otalgia
3.4
70.9
381
1139
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.2
70.2
818
3862
J01DA01
ATC
[U] cefalexin; systemic
1.7
68.8
2457
17396
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
83.3
68.4
78
9
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
12.5
67.3
125
97
J45.9
ICD-10 Finland
Asthma, unspecified
2.2
66.5
751
3487
J45.1
ICD-10 Finland
Nonallergic asthma
3.1
63.6
389
1274
J01FA09
ATC
clarithromycin; systemic
1.8
63.3
1379
8276
H60.8
ICD-10 Finland
Other otitis externa
5.2
61.6
201
377
ZXA10
NOMESCO Finland
Bilateral
2.2
61.3
692
3200
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
59.2
58
*
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
+∞
59.2
58
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
58.6
2402
17331
R03AC02
ATC
salbutamol; inhalant
1.7
58.0
2199
15507
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.9
56.8
1057
5965
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.1
55.1
321
1013
R03BA05
ATC
fluticasone; inhalant
2.0
54.6
859
4550
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
138.7
53.7
58
*
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.6
53.6
434
1686
J01DA08
ATC
[U] cefaclor; oral
2.0
52.1
826
4374
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
11.5
51.6
99
83
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.8
51.4
179
361
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
50.7
704
3537
H66
ICD-10 Finland
Suppurative and unspecified otitis media
3.8
49.8
225
582
R01AD09
ATC
mometasone; nasal
1.6
49.1
1821
12552
J01DB01
ATC
cefalexin; oral
1.7
48.2
3425
27914
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
48.0
47
*
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.3
47.3
485
2126
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
47.0
46
*
S02CA02
ATC
flumetasone and antiinfectives; otic
3.5
46.2
227
630
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.6
45.4
358
1364
DGW00
NOMESCO Finland
Dilatation of eustachian tube
436.9
45.3
46
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
45.3
722
3814
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
+∞
44.9
44
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
44.5
790
4333
H02AB06
ATC
prednisolone; systemic
1.6
43.9
1571
10635
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
9.0
43.3
94
100
H29
ICPC
Ear symptom/complaint other
2.3
43.1
420
1792
4141
FHL
Myringoplasty (also for reasons other than inflammation)
+∞
41.8
41
*
R50.9
ICD-10 Finland
Fever, unspecified
1.9
41.4
652
3415
R03BA02
ATC
budesonide; inhalant
1.9
40.7
701
3794
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.4
39.9
209
609
J01DA06
ATC
[U] cefuroxime; systemic
2.1
39.9
512
2472
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
5.5
39.6
122
215
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
39.3
796
4546
R01AD08
ATC
fluticasone; nasal
1.7
39.2
1056
6576
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
39.1
1528
10493
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.4
38.8
366
1533
TDA90
NOMESCO Finland
Removal wax from ear
9.0
38.6
84
90
38700
ICD-8 Finland
Other disease of ear and mastoid process, Cholesteatoma of ear
+∞
37.8
37
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
37.7
1276
8434
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.5
36.1
310
1236
J04.0
ICD-10 Finland
Acute laryngitis
2.6
35.6
270
1006
R03DC03
ATC
montelukast; oral
1.8
35.3
646
3554
4451
FHL
Guitar cutting
3.5
35.2
170
466
R51.80
ICD-10 Finland
Headache
1.8
34.9
743
4294
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
120.6
34.9
38
*
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
+∞
34.7
34
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
34.5
967
6052
H04
ICPC
Ear discharge
4.0
34.1
143
347
M01AE02
ATC
naproxen; oral, rectal
1.5
33.5
2447
19070
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
4.5
33.3
123
265
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
3.4
32.6
167
479
R01AD12
ATC
fluticasone furoate; nasal
1.5
32.0
1278
8719
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
31.8
729
4298
H02AB04
ATC
methylprednisolone; systemic
2.0
31.3
433
2146
Z97.4
ICD-10 Finland
Presence of external hearing-aid
4.2
31.2
122
278
R03CC02
ATC
salbutamol; systemic
1.7
31.1
738
4394
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
+∞
30.6
30
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.4
29.9
263
1062
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
4.1
29.7
119
278
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
+∞
29.6
29
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.4
29.3
269
1110
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
287.3
29.2
30
*
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
2.3
28.7
282
1204
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
+∞
28.6
28
*
EMB10
NOMESCO Finland
Tonsillectomy
2.0
27.6
375
1842
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
27.6
443
2319
DEB30
NOMESCO Finland
Radical mastoidectomy
+∞
27.5
27
*
DCW00
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
+∞
27.5
27
*
J01MA02
ATC
ciprofloxacin; systemic
1.5
27.5
1079
7283
TDC10
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
267.4
27.1
28
*
H60
ICD-10 Finland
Otitis externa
2.5
27.0
220
853
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
5.9
26.8
77
126
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
+∞
26.5
26
*
H71
ICPC
Acute otitis media/myringitis
3.7
26.3
118
306
R42
ICD-10 Finland
Dizziness and giddiness
1.7
26.2
638
3811
H92.1
ICD-10 Finland
Otorrhoea
17.7
26.0
41
22
H73.1
ICD-10 Finland
Chronic myringitis
+∞
25.5
25
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
25.4
509
2865
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.6
25.4
194
726
J35.8
ICD-10 Finland
Other chronic diseases of tonsils and adenoids
4.6
24.9
88
183
J01AA02
ATC
doxycycline; systemic
1.4
24.5
2390
19137
H70.0
ICD-10 Finland
Acute mastoiditis
+∞
24.5
24
*
3810A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Acute nonsuppurative otitis media
+∞
24.5
24
*
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.5
24.5
923
6151
B34.9
ICD-10 Finland
Viral infection, unspecified
2.5
24.4
201
785
M79.6
ICD-10 Finland
Pain in limb
1.5
24.4
1183
8321
DCD10
NOMESCO Finland
Tympanoplasty
66.4
24.2
28
*
N02AX02
ATC
tramadol; systemic, rectal
1.5
24.1
1127
7865
J01FF01
ATC
clindamycin; systemic
1.5
24.1
832
5431
J35.1
ICD-10 Finland
Hypertrophy of tonsils
2.7
23.7
169
607
J01DC02
ATC
cefuroxime; systemic
2.3
23.6
232
990
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
23.5
784
5067
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
7.5
23.5
56
71
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
22.9
584
3523
XG410
NOMESCO Finland
Flow-volume spirometry
2.6
22.6
169
625
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.9
22.5
140
462
R03AC03
ATC
terbutaline; inhalant
1.7
22.3
490
2830
N02BE01
ATC
paracetamol; systemic, rectal
1.4
22.2
3109
26253
H13
ICPC
Plugged feeling ear
1.7
21.9
545
3260
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
21.8
2069
16346
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
21.7
262
1227
J01MA12
ATC
levofloxacin; systemic
1.7
21.5
463
2661
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
21.4
621
3871
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
21.3
3093
26162
J45.8
ICD-10 Finland
Mixed asthma
2.9
21.1
131
432
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
8.4
20.8
46
52
DAX08
NOMESCO Finland
Fitting of hearing aid
3.4
20.8
103
291
K02.1
ICD-10 Finland
Caries of dentine
1.4
20.6
2548
20931
R06.2
ICD-10 Finland
Wheezing
2.3
20.5
195
817
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
20.5
1948
15342
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
1.8
20.4
391
2165
DEA10
NOMESCO Finland
Attico-antrotomy
+∞
20.4
20
*
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
20.3
2910
24442
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
6.7
20.3
52
74
R06AE07
ATC
cetirizine; oral
1.4
20.2
1744
13512
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.5
20.2
852
5790
R05
ICPC
Cough
1.5
20.1
922
6369
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
20.1
455
2651
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.3
20.0
187
780
SPAT1260
SPAT
Consultation of another employee
1.5
19.9
676
4375
127
Kela drug reimbursment
Transplant complication
4.4
19.9
73
159
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.4
19.8
180
740
ZXA00
NOMESCO Finland
Right side
1.5
19.6
679
4414
DFF15
NOMESCO Finland
Speech audiometry
3.2
19.6
106
320
SPAT1312
SPAT
General health counselling
1.4
19.5
1661
12816
J46
ICD-10 Finland
Status asthmaticus
3.2
19.5
104
311
H69.0
ICD-10 Finland
Patulous Eustachian tube
15.2
19.4
32
20
DEB00
NOMESCO Finland
Cortical mastoidectomy
+∞
19.4
19
*
Z94.0
ICD-10 Finland
Kidney transplant status
5.3
19.4
60
109
SPAT1263
SPAT
Sampling
1.3
19.2
1793
14030
R5120
NOMESCO Finland
Preparation of an aid
4.0
19.1
77
183
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
3.2
19.1
102
305
DC1BD
NOMESCO Finland
Temporal bone extensive CT
189.6
19.1
20
*
J32.4
ICD-10 Finland
Chronic pansinusitis
4.5
19.1
68
144
R06.0
ICD-10 Finland
Dyspnoea
1.5
18.9
700
4616
L04AA06
ATC
mycophenolic acid; systemic
4.0
18.8
77
186
602
Kela drug reimbursment
Children's severe malnutrition
5.9
18.8
53
86
H60.4
ICD-10 Finland
Cholesteatoma of external ear
19.0
18.4
28
14
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
18.4
748
5028
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.9
18.4
77
190
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
+∞
18.4
18
*
H95.8
ICD-10 Finland
Other postprocedural disorders of ear and mastoid process
+∞
18.4
18
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
18.3
675
4444
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.1
18.3
218
1014
A02BC02
ATC
pantoprazole; systemic
1.3
18.3
1864
14749
H61.2
ICD-10 Finland
Impacted cerumen
2.2
18.2
187
815
M25.5
ICD-10 Finland
Pain in joint
1.4
18.2
949
6710
H70
ICPC
Otitis externa
3.1
18.1
103
320
R01BA51
ATC
phenylpropanolamine, combinations; oral
1.5
18.0
710
4742
R74
ICPC
Upper respiratory infection acute
1.4
17.9
1495
11456
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.7
17.9
386
2215
H73.0
ICD-10 Finland
Acute myringitis
7.8
17.8
41
50
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
5.2
17.8
55
100
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
17.7
928
6561
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
17.7
540
3401
N03AX16
ATC
pregabalin; oral
1.5
17.5
600
3881
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
17.5
1220
9074
R96
ICPC
Asthma
1.8
17.4
304
1633
A02BC01
ATC
omeprazole; systemic
1.5
17.3
746
5073
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
17.1
17.2
27
15
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.9
17.2
277
1450
WX110
NOMESCO Finland
Local anesthesy
1.3
17.1
2930
24900
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
17.0
2348
19334
UDM02
NOMESCO Finland
Sinoscopy
3.3
16.9
87
254
J01.9
ICD-10 Finland
Acute sinusitis, unspecified
2.3
16.8
152
626
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
16.7
896
6352
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
16.5
2233
18305
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
16.4
904
6438
4144
FHL
Mastoidectomy or aticomastoidectomy
+∞
16.3
16
*
DCA40
NOMESCO Finland
Fat patching or other similar technique without opening of tympanic membrane
+∞
16.3
16
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.0
16.2
214
1040
H60.1
ICD-10 Finland
Cellulitis of external ear
3.8
16.1
68
170
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
16.0
509
3234
R03CC03
ATC
terbutaline; systemic
2.0
16.0
210
1017
R11
ICD-10 Finland
Nausea and vomiting
1.7
16.0
325
1831
M54.5
ICD-10 Finland
Low back pain
1.4
15.5
1085
8042
XQ800
NOMESCO Finland
Prick test
1.7
15.5
344
1992
E66.01
ICD-10 Finland
Obesity due to excess calories
1.8
15.5
284
1551
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.8
15.3
101
350
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
15.3
454
2834
H66.2
ICD-10 Finland
Chronic atticoantral suppurative otitis media
+∞
15.3
15
*
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
15.3
669
4555
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
15.3
1748
13942
R05
ICD-10 Finland
Cough
1.5
15.3
650
4402
A08.0
ICD-10 Finland
Rotaviral enteritis
3.7
15.2
66
169
ZXA05
NOMESCO Finland
Left side
1.5
15.2
611
4087
DCW99
NOMESCO Finland
Other operation on eardrum and middle ear
80.6
15.2
17
*
J45
ICD-10 Finland
Asthma
1.7
15.1
330
1900
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.7
15.1
102
359
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.4
15.1
126
499
Z71.8
ICD-10 Finland
Other specified counselling
1.4
15.0
992
7275
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
2.7
15.0
103
366
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
15.0
1277
9752
N05BA01
ATC
diazepam; systemic, rectal
1.6
14.9
368
2192
J33.0
ICD-10 Finland
Polyp of nasal cavity
3.0
14.9
86
274
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
14.8
423
2614
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
14.8
1627
12889
S06.0
ICD-10 Finland
Concussion
1.6
14.7
437
2731
H27
ICPC
Fear of ear disease
3.6
14.6
66
175
R06AX27
ATC
desloratadine; oral
1.3
14.6
1132
8512
G47.3
ICD-10 Finland
Sleep apnoea
1.5
14.6
478
3053
A03
ICPC
Fever
1.4
14.6
882
6373
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
4.8
14.5
48
95
SPAT1310
SPAT
Counselling related to known health issue
1.3
14.5
1395
10840
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
4.2
14.4
55
126
L03
ICPC
Low back symptom/complaint
1.4
14.4
898
6519
BE00A
NOMESCO Finland
NA
30.0
14.4
19
6
L17
ICPC
Foot/toe symptom/complaint
1.4
14.3
949
6956
H95.0
ICD-10 Finland
Recurrent cholesteatoma of postmastoidectomy cavity
+∞
14.3
14
*
H60.0
ICD-10 Finland
Abscess of external ear
5.2
14.2
44
81
H72
ICD-10 Finland
Perforation of tympanic membrane
19.9
14.2
21
10
4121
FHL
Tympanic puncture or parasentosis in general anesthesia or operating room
4.6
14.2
49
102
SPAT1301
SPAT
No procedures
1.3
14.1
1230
9405
4742A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Adenoid vegetations
2.9
14.1
87
289
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.1
14.1
154
693
R62.0
ICD-10 Finland
Delayed milestone
3.6
14.1
64
171
R21
ICPC
Throat symptom/complaint
1.3
13.9
1262
9704
P01AB01
ATC
metronidazole; oral, rectal
1.3
13.8
1170
8904
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
13.8
359
2168
S18
ICPC
Laceration/cut
1.3
13.7
1293
9996
WX290
NOMESCO Finland
Other blockade of nerve
1.3
13.7
2027
16641
SPAT1262
SPAT
Handing over of treatment supplies
1.5
13.7
431
2730
E66.8
ICD-10 Finland
Other obesity
2.1
13.6
162
757
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.7
13.6
267
1490
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.5
13.5
541
3610
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
1.6
13.5
321
1894
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
+∞
13.3
13
*
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.5
13.2
457
2956
WX400
NOMESCO Finland
Inhalation anesthesy
2.0
13.0
173
845
UKC02
NOMESCO Finland
Cystoscopy
1.6
13.0
329
1969
-1
NOMESCO Finland
NA
1.3
13.0
1772
14364
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.7
13.0
282
1621
XF600
NOMESCO Finland
Bloodpressure measurement
1.8
13.0
219
1164
A01AB09
ATC
miconazole; local oral
1.7
12.9
266
1505
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
8.8
12.9
27
29
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
3.1
12.8
70
216
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
12.7
1893
15498
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
12.7
648
4527
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
12.7
1103
8406
N30.0
ICD-10 Finland
Acute cystitis
1.5
12.7
500
3325
UJF32
NOMESCO Finland
Coloscopy
1.4
12.5
602
4163
J01EA01
ATC
trimethoprim; systemic
1.4
12.5
779
5643
H02
ICPC
Hearing complaint
1.7
12.4
258
1464
G44.2
ICD-10 Finland
Tension-type headache
1.5
12.3
470
3106
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
12.2
916
6825
T78.4
ICD-10 Finland
Allergy, unspecified
1.8
12.1
208
1114
R03BB04
ATC
tiotropium bromide; inhalant
1.9
12.1
185
950
J01FA06
ATC
roxithromycin; oral
1.3
12.1
1092
8363
R03BA01
ATC
beclometasone; inhalant
1.6
12.0
359
2246
N06AX11
ATC
mirtazapine; oral
1.3
11.9
934
7001
R02
ICPC
Shortness of breath/dyspnoea
1.5
11.9
381
2420
R53
ICD-10 Finland
Malaise and fatigue
1.4
11.9
678
4831
WX002
NOMESCO Finland
Sedation and analgesia
1.5
11.8
491
3298
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.8
11.8
74
251
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
11.8
556
3831
L04AA01
ATC
[U] ciclosporin; systemic
3.7
11.7
50
128
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.4
11.7
520
3543
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
11.7
267
1557
SPAT1044
SPAT
Tympanometry
2.3
11.6
106
440
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
3.5
11.6
54
149
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
11.6
3101
27100
R07.3
ICD-10 Finland
Other chest pain
1.7
11.5
246
1406
L12
ICPC
Hand/finger symptom/complaint
1.4
11.5
640
4538
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
11.5
225
1254
J01MA14
ATC
moxifloxacin; systemic
1.8
11.5
208
1135
J12.9
ICD-10 Finland
Viral pneumonia, unspecified
4.6
11.5
39
81
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.7
11.5
265
1550
F83
ICD-10 Finland
Mixed specific developmental disorders
3.0
11.4
65
205
Z00.0
ICD-10 Finland
General medical examination
1.4
11.3
752
5495
XG474
NOMESCO Finland
Exhalation nntrogen oxide
2.2
11.3
114
497
H70.9
ICD-10 Finland
Mastoiditis, unspecified
+∞
11.2
11
*
38400
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) acuta
+∞
11.2
11
*
H73.8
ICD-10 Finland
Other specified disorders of tympanic membrane
21.7
11.2
16
7
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.4
11.1
91
357
R03AC12
ATC
salmeterol; inhalant
2.2
11.1
108
462
R06AE09
ATC
levocetirizine; oral
1.4
11.1
559
3893
A41.9
ICD-10 Finland
Sepsis, unspecified
2.5
11.1
88
341
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.9
11.1
153
758
J01DC04
ATC
cefaclor; oral
2.7
11.1
75
267
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
11.1
898
6760
N01
ICPC
Headache
1.3
11.1
846
6314
J20
ICD-10 Finland
Acute bronchitis
1.6
11.0
281
1692
R06AX13
ATC
loratadine; oral
1.4
11.0
553
3856
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
11.0
440
2936
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
11.0
481
3267
AA1AD
NOMESCO Finland
CT of head and brain
1.4
10.9
526
3632
N05AH04
ATC
quetiapine; oral
1.4
10.9
641
4588
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.6
10.8
295
1801
R05FB02
ATC
cough suppressants and expectorants
1.3
10.8
851
6376
H69.9
ICD-10 Finland
Eustachian tube disorder, unspecified
8.4
10.8
23
26
R01AD11
ATC
triamcinolone; nasal
1.6
10.8
250
1464
UGC02
NOMESCO Finland
Rigid bronchoscopy
5.7
10.7
30
50
N07CA01
ATC
betahistine; oral
1.9
10.7
152
761
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
1.5
10.7
337
2132
N06AX16
ATC
venlafaxine; oral
1.4
10.7
461
3117
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
4.1
10.7
40
92
R01AD01
ATC
beclometasone; nasal
1.5
10.7
397
2606
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.9
10.6
149
744
H02AB09
ATC
hydrocortisone; systemic
2.3
10.6
96
398
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.5
10.5
320
2013
SBB10
NOMESCO Finland
Teeth copy
1.4
10.4
522
3628
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.9
10.4
152
772
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
26.5
10.4
14
5
FM2CE
NOMESCO Finland
NA
3.0
10.4
60
193
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
56.8
10.4
12
*
EBA00
NOMESCO Finland
Extraction of tooth
1.3
10.3
1381
11083
XF622
NOMESCO Finland
Measurement of minute volume of heart
8.3
10.3
22
25
J31.0
ICD-10 Finland
Chronic rhinitis
1.6
10.3
242
1423
B03XA01
ATC
erythropoietin; parenteral
5.4
10.3
30
53
R01AD05
ATC
budesonide; nasal
1.7
10.2
206
1162
N05BA04
ATC
oxazepam; oral
1.3
10.1
708
5206
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
2.9
10.1
59
192
J03.0
ICD-10 Finland
Streptococcal tonsillitis
1.7
10.1
207
1173
Q20.48
ICD-10 Finland
Single ventricle
30.8
10.0
13
*
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
4.1
10.0
38
89
J01FA15
ATC
telithromycin; oral
1.6
9.9
240
1422
J33.8
ICD-10 Finland
Other polyp of sinus
3.0
9.9
57
183
X58
ICD-10 Finland
Exposure to other specified factors
1.4
9.9
509
3559
C03CA01
ATC
furosemide; systemic
1.4
9.9
464
3191
N03AX12
ATC
gabapentin; oral
1.5
9.9
362
2371
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
4.7
9.9
32
64
A02BC05
ATC
esomeprazole; systemic
1.3
9.8
1017
7898
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
9.8
676
4958
J30.3
ICD-10 Finland
Other allergic rhinitis
1.8
9.8
155
810
L01
ICPC
Neck symptom/complaint
1.4
9.8
492
3421
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.5
9.8
312
1981
S29
ICPC
Skin symptom/complaint other
1.4
9.8
572
4087
SPAT1254
SPAT
Administration of medicine
1.3
9.7
738
5489
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.1
9.7
103
460
H69.8
ICD-10 Finland
Other specified disorders of Eustachian tube
7.0
9.7
23
31
T82
ICPC
Obesity
1.9
9.7
132
654
L04AD01
ATC
ciclosporin; systemic
2.6
9.7
69
253
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
9.7
647
4724
F51.0
ICD-10 Finland
Nonorganic insomnia
1.4
9.6
463
3197
S80.0
ICD-10 Finland
Contusion of knee
1.6
9.6
251
1521
L15
ICPC
Knee symptom/complaint
1.3
9.6
749
5595
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.7
9.6
211
1222
G43.9
ICD-10 Finland
Migraine, unspecified
1.6
9.5
272
1684
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.6
9.5
258
1576
DHB20
NOMESCO Finland
Polypectomy of internal nose
3.4
9.5
44
122
J47
ICD-10 Finland
Bronchiectasis
3.4
9.5
45
127
ZX120
NOMESCO Finland
Intravenous
1.6
9.5
250
1518
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.8
9.5
154
813
H02AB07
ATC
prednisone; oral
1.5
9.5
329
2130
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.4
9.5
503
3537
R03AK08
ATC
formoterol and beclometasone; inhalant
2.1
9.5
99
441
K52.2
ICD-10 Finland
Allergic and dietetic gastroenteritis and colitis
2.5
9.4
74
286
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
9.4
201
1154
R06.5
ICD-10 Finland
Mouth breathing
1.6
9.4
232
1385
4150
FHL
Tympanoplasty (including for reasons other than inflammation)
52.0
9.4
11
*
C01CA24
ATC
epinephrine; parenteral
1.6
9.4
261
1603
J00
ICD-10 Finland
Acute nasopharyngitis [common cold]
2.2
9.4
96
423
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.6
9.4
270
1677
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
9.3
781
5890
H81.3
ICD-10 Finland
Other peripheral vertigo
2.7
9.3
63
226
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
9.3
865
6621
RD210
NOMESCO Finland
NA
2.1
9.3
98
440
J02AC01
ATC
fluconazole; systemic
1.3
9.2
1198
9551
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.7
9.2
202
1170
M31.3
ICD-10 Finland
Wegener granulomatosis
7.4
9.2
21
27
B01.9
ICD-10 Finland
Varicella without complication
3.5
9.2
41
111
4145
FHL
Tympanomastoidectomy, includes possible tympanoplasty
+∞
9.2
9
*
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
3.1
9.1
49
152
Z96.2
ICD-10 Finland
Presence of otological and audiological implants
28.4
9.1
12
*
SPAT1043
SPAT
Audiometry
1.5
9.1
273
1709
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.4
9.1
76
306
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.3
9.1
780
5901
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.8
9.1
55
185
61
HP
Catheterization and pressure measurement of the left side of the heart
3.6
9.0
39
103
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.8
9.0
54
181
-69
ICPC
Other reason for encounter NEC
1.9
9.0
128
646
R07.0
ICD-10 Finland
Pain in throat
1.5
8.9
280
1770
5AB14
NOMESCO Finland
NA
10.1
8.9
17
16
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
4.5
8.9
30
63
31
HP
Congenital heart failure surgery
4.7
8.9
29
59
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
1.8
8.9
161
881
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
8.8
235
1431
A02BC03
ATC
lansoprazole; oral
1.3
8.8
621
4568
A04
ICPC
Weakness/tiredness general
1.3
8.8
576
4187
SPAT1283
SPAT
Restricted health certificate
1.3
8.8
1045
8240
R56.0
ICD-10 Finland
Febrile convulsions
2.6
8.8
60
216
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
8.8
1118
8887
H90.2
ICD-10 Finland
Conductive hearing loss, unspecified
6.9
8.8
21
29
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
34.7
8.8
11
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
4.2
8.7
32
73
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
1.7
8.7
184
1053
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.6
8.7
218
1304
S02AA30
ATC
antiinfectives, combinations; otic
1.6
8.7
210
1244
F90.0
ICD-10 Finland
Disturbance of activity and attention
1.6
8.7
207
1226
K59.09
ICD-10 Finland
Constipation, unspecified
1.8
8.7
149
802
A03FA02
ATC
cisapride; oral, rectal
1.7
8.7
182
1042
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.4
8.6
373
2525
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
2.7
8.6
55
191
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
8.6
237
1457
T07
ICPC
Weight gain
2.3
8.6
73
298
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
1.6
8.6
194
1133
A06AD11
ATC
lactulose; oral
1.5
8.5
300
1946
J32.2
ICD-10 Finland
Chronic ethmoidal sinusitis
4.1
8.5
32
75
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.6
8.5
224
1362
J21.90
ICD-10 Finland
Acute obstructive bronchitis in children
6.1
8.5
22
34
F80.1
ICD-10 Finland
Expressive language disorder
2.7
8.5
55
193
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
47.3
8.5
10
*
50301
ICD-8 Finland
Chronic sinusitis, Maxillaris NUD
4.6
8.5
28
58
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.4
8.4
385
2631
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.0
8.4
103
492
R52.9
ICD-10 Finland
Pain, unspecified
1.5
8.4
247
1539
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.7
8.4
155
853
N06AB10
ATC
escitalopram; oral
1.3
8.4
765
5830
S60.0
ICD-10 Finland
Contusion of finger(s) without damage to nail
1.8
8.4
151
825
J34.2
ICD-10 Finland
Deviated nasal septum
1.8
8.4
135
714
J01.1
ICD-10 Finland
Acute frontal sinusitis
2.5
8.3
64
246
L20.0
ICD-10 Finland
Besnier prurigo
1.4
8.3
394
2715
N06AA09
ATC
amitriptyline; systemic
1.6
8.3
198
1174
L16
ICPC
Ankle symptom/complaint
1.4
8.3
462
3275
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.5
8.3
284
1836
T16
ICD-10 Finland
Foreign body in ear
3.1
8.3
44
137
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.5
8.3
322
2136
Z99.2
ICD-10 Finland
Dependence on renal dialysis
10.9
8.2
15
13
H77
ICPC
Perforation ear drum
26.0
8.2
11
*
H74.0
ICD-10 Finland
Tympanosclerosis
85.2
8.2
9
*
UJD02
NOMESCO Finland
Gastroscopy
1.9
8.2
112
558
F43.8
ICD-10 Finland
Other reactions to severe stress
2.1
8.2
93
432
N06AA12
ATC
doxepin; systemic
1.9
8.2
108
532
WX704
NOMESCO Finland
Intubation
1.6
8.2
195
1154
U07
ICPC
Urine symptom/complaint other
1.7
8.2
153
848
H74
ICPC
Chronic otitis media
+∞
8.2
8
*
3824A
ICD-9 Finland
Suppurative and unspecified otitis media, Unspecified suppurative otitis media
+∞
8.2
8
*
J20.0
ICD-10 Finland
Acute bronchitis due to Mycoplasma pneumoniae
4.7
8.1
26
52
R01BA01
ATC
phenylpropanolamine; oral
1.8
8.1
129
677
J06.80
ICD-10 Finland
Continuously repeating infections of a child
6.5
8.1
20
29
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
4.0
8.1
31
74
Z01.9
ICD-10 Finland
Special examination, unspecified
1.8
8.1
138
741
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.2
8.1
78
338
L04AX01
ATC
azathioprine; systemic
1.8
8.1
145
793
Q35.1
ICD-10 Finland
Cleft hard palate
12.1
8.1
14
11
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
2.4
8.0
65
256
R04.0
ICD-10 Finland
Epistaxis
1.7
8.0
162
915
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.5
8.0
278
1802
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.5
8.0
235
1467
L01AA01
ATC
cyclophosphamide; systemic
10.1
8.0
15
14
Z50.5
ICD-10 Finland
Speech therapy
2.5
8.0
60
231
K04.1
ICD-10 Finland
Necrosis of pulp
1.5
7.9
300
1980
R73.9
ICD-10 Finland
Hyperglycaemia, unspecified
2.4
7.9
65
260
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
1.7
7.9
161
913
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.7
7.9
147
814
E66.9
ICD-10 Finland
Obesity, unspecified
1.9
7.9
111
559
E0000UV
ATC
NA
1.2
7.9
1478
12224
183
Kela drug reimbursment
Lamotrigin and topiramate
2.8
7.9
47
158
FAE10
NOMESCO Finland
Bidirectional anastomosis between superior vena cava and pulmonary artery
31.5
7.9
10
*
XF602
NOMESCO Finland
Bloodpressure monitoring
3.1
7.9
40
121
A01
ICPC
Pain general/multiple sites
1.5
7.8
232
1452
SPAT1315
SPAT
Periodic health check-up of children and adolescents
1.2
7.8
1216
9860
N05CF02
ATC
zolpidem; oral
1.4
7.8
420
2957
ZXC10
NOMESCO Finland
Use of laser
2.5
7.8
58
221
137
Kela drug reimbursment
Uraemia requiring dialysis
4.0
7.8
29
68
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
7.8
397
2772
M54.2
ICD-10 Finland
Cervicalgia
1.6
7.7
190
1134
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.3
7.7
547
4025
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
1.9
7.7
106
531
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
5.1
7.7
23
43
K04.0
ICD-10 Finland
Pulpitis
1.4
7.7
341
2321
P01
ICPC
Feeling anxious/nervous/tense
1.3
7.7
746
5729
WX882
NOMESCO Finland
High dependency care
2.0
7.7
89
419
WW200
NOMESCO Finland
Immunization
2.0
7.6
91
432
L01.0
ICD-10 Finland
Impetigo [any organism] [any site]
2.0
7.6
88
411
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
2.8
7.6
46
156
R1260
NOMESCO Finland
Evaluation of communicative skills
2.9
7.6
44
144
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.2
7.6
1271
10378
B05DA
ATC
Isotonic solutions
4.6
7.6
25
52
J20.5
ICD-10 Finland
Acute bronchitis due to respiratory syncytial virus
6.8
7.6
18
25
J11.1
ICD-10 Finland
Influenza with other respiratory manifestations, virus not identified
2.1
7.6
79
355
N06AB04
ATC
citalopram; systemic
1.3
7.6
531
3897
A11CC03
ATC
alfacalcidol; systemic
2.5
7.6
56
212
K03.66
ICD-10 Finland
Tooth plaque
1.5
7.5
268
1746
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
7.5
259
1675
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.2
7.5
1363
11217
120
Kela drug reimbursment
Hypogammaglobulinaemia
8.9
7.5
15
16
L27.2
ICD-10 Finland
Dermatitis due to ingested food
1.9
7.4
102
512
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.4
7.4
445
3190
Z94.4
ICD-10 Finland
Liver transplant status
6.6
7.4
18
26
N06BA04
ATC
methylphenidate; oral
1.7
7.4
158
912
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.4
7.4
330
2248
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.0
7.4
91
438
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
2.4
7.4
61
246
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
23.6
7.3
10
*
SPAT1307
SPAT
Psychosocial counselling and guidance
1.3
7.3
487
3546
62
HP
Catheterization and pressure measurement of the right side of the heart
6.0
7.3
19
30
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.5
7.3
262
1708
R06.8
ICD-10 Finland
Other and unspecified abnormalities of breathing
2.6
7.3
51
188
B05DB
ATC
Hypertonic solutions
5.0
7.3
22
42
F82
ICD-10 Finland
Specific developmental disorder of motor function
2.8
7.3
44
150
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.0
7.2
85
399
7490A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS COMPLETA]
75.7
7.2
8
*
FBA96
NOMESCO Finland
Other suture or repair of pulmonary artery
75.7
7.2
8
*
D01
ICPC
Abdominal pain/cramps general
1.3
7.2
535
3956
TFJ02
NOMESCO Finland
Muscle biopsy of heart
9.5
7.2
14
14
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.0
7.2
90
436
H01AC01
ATC
somatropin; parenteral
3.6
7.2
30
78
J35.0
ICD-10 Finland
Chronic tonsillitis
1.5
7.2
255
1658
H03AA01
ATC
levothyroxine sodium; systemic
1.3
7.2
576
4309
S90.3
ICD-10 Finland
Contusion of other and unspecified parts of foot
1.8
7.2
113
592
SPAT1211
SPAT
Application of soft bandage
1.4
7.2
384
2704
N03AF02
ATC
oxcarbazepine; oral
1.9
7.1
105
537
D07AA02
ATC
hydrocortisone; topical
1.3
7.1
580
4349
3813X
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Other and unspecified chronic nonsuppurative otitis media
+∞
7.1
7
*
H74.4
ICD-10 Finland
Polyp of middle ear
+∞
7.1
7
*
4147
FHL
Radical surgery, cavity filling and middle ear and / or eardrum plastic
+∞
7.1
7
*
4364
FHL
Pharyngeal tongue plastic
+∞
7.1
7
*
Z97.8
ICD-10 Finland
Presence of other specified devices
5.1
7.1
21
39
D19
ICPC
Teeth/gum symptom/complaint
1.2
7.1
1024
8221
R06AX22
ATC
ebastine; oral
1.3
7.1
467
3397
48609
ICD-8 Finland
Pneumonia, unspecified
3.0
7.1
38
120
A07AA02
ATC
nystatin; oral
1.7
7.1
129
710
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
7.1
808
6322
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.3
7.0
472
3445
N30.9
ICD-10 Finland
Cystitis, unspecified
1.6
7.0
167
990
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.5
7.0
197
1220
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
10.3
7.0
13
12
J01.4
ICD-10 Finland
Acute pansinusitis
3.3
7.0
33
95
103
Kela drug reimbursment
Diabetes, insulin-treated
1.3
7.0
511
3773
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.4
7.0
278
1856
N05CF01
ATC
zopiclone; oral
1.3
7.0
696
5359
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
5.3
7.0
20
36
TQW99
NOMESCO Finland
Other minor procedure on skin
1.8
7.0
106
552
K10.3
ICD-10 Finland
Alveolitis of jaws
1.6
7.0
163
962
XFE00
NOMESCO Finland
Epicardial ultrasonography
2.4
7.0
53
206
UDC10
NOMESCO Finland
Tympanoscopy
28.4
6.9
9
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.5
6.9
202
1260
N03AG01
ATC
valproic acid; systemic, rectal
1.6
6.9
182
1107
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.3
6.9
777
6066
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.0
6.9
85
409
D80.0
ICD-10 Finland
Hereditary hypogammaglobulinaemia
18.9
6.9
10
5
R06.4
ICD-10 Finland
Hyperventilation
2.2
6.9
64
274
D06
ICPC
Abdominal pain localized other
1.4
6.9
319
2189
K59.0
ICD-10 Finland
Constipation
1.6
6.9
159
936
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.5
6.9
198
1231
R83
ICPC
Respiratory infection other
1.2
6.9
1187
9708
K56.0
ICD-10 Finland
Paralytic ileus
4.9
6.8
21
41
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.5
6.8
259
1712
1450
FHL
Otomicroscopy
4.2
6.8
24
54
SPAT1215
SPAT
Assessment of need for medical rehabilitation
1.7
6.8
135
762
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.4
6.8
303
2064
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
1.7
6.8
142
815
S40.0
ICD-10 Finland
Contusion of shoulder and upper arm
1.7
6.8
121
662
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
1.8
6.8
119
647
H65
ICD-10 Finland
Nonsuppurative otitis media
2.8
6.8
40
134
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.3
6.8
57
231
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
6.8
1178
9638
N18.8
ICD-10 Finland
Other chronic renal failure
2.4
6.8
54
214
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
8.3
6.8
14
16
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
6.8
481
3541
R09
ICPC
Sinus symptom/complaint
1.4
6.7
287
1937
D10
ICPC
Vomiting
1.4
6.7
326
2254
W22
ICD-10 Finland
Striking against or struck by other object(s)
1.5
6.7
243
1590
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.3
6.7
428
3101
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
1.7
6.6
135
769
SPAT1316
SPAT
Extensive health check-up of children and adolescents
1.2
6.6
811
6394
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
1.8
6.6
103
541
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.5
6.6
232
1509
R35
ICD-10 Finland
Polyuria
1.7
6.6
133
753
S02AA03
ATC
boric acid; otic
3.8
6.6
26
65
K07.60
ICD-10 Finland
Snapping jaw
1.5
6.6
186
1152
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
1.5
6.6
239
1564
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.5
6.6
198
1245
FQA00
NOMESCO Finland
Orthotopic transplantation of heart
37.8
6.6
8
*
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
2.2
6.6
61
260
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.3
6.5
522
3904
W19
ICD-10 Finland
Unspecified fall
1.4
6.5
302
2071
T90
ICPC
Diabetes non-insulin dependent
1.3
6.5
389
2787
4741B
ICD-9 Finland
Chronic disease of tonsils and adenoids, Hypertrophy of tonsils and adenoids[HYPERTROPHIA TONSILLAE PHARYNGICAE]
2.4
6.5
50
195
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.5
6.5
244
1609
L50.9
ICD-10 Finland
Urticaria, unspecified
1.6
6.5
149
875
ZZG00
NOMESCO Finland
Graft of cartilage
7.8
6.5
14
17
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
1.5
6.5
238
1559
M31.1
ICD-10 Finland
Thrombotic microangiopathy
15.8
6.5
10
6
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
2.2
6.5
64
282
H16.0
ICD-10 Finland
Corneal ulcer
1.7
6.5
129
730
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.4
6.5
332
2317
E84.0
ICD-10 Finland
Cystic fibrosis with pulmonary manifestations
21.3
6.5
9
*
DDD05
NOMESCO Finland
Plastic repair of ossicular chain
21.3
6.5
9
*
49300
ICD-8 Finland
Asthma, bronchiale
2.6
6.5
44
162
OIKK
NOMESCO Finland
NA
1.4
6.5
353
2495
ZX108
NOMESCO Finland
Inhalation
3.4
6.5
29
81
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.4
6.4
373
2662
M79.1
ICD-10 Finland
Myalgia
1.3
6.4
406
2938
L29.9
ICD-10 Finland
Pruritus, unspecified
2.1
6.4
65
289
R03BB01
ATC
ipratropium bromide; inhalant
2.2
6.4
63
278
C08CA01
ATC
amlodipine; oral
1.3
6.4
582
4431
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.7
6.4
136
787
SPAT1039
SPAT
Otomicroscopy
2.0
6.3
74
349
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
1.4
6.3
287
1961
Z94.1
ICD-10 Finland
Heart transplant status
7.4
6.3
14
18
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
4.4
6.3
21
45
RS211
NOMESCO Finland
NA
3.2
6.3
30
88
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
3.3
6.3
29
83
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
2.3
6.3
55
231
R75
ICPC
Sinusitis acute/chronic
1.6
6.3
145
857
J01
ICD-10 Finland
Acute sinusitis
1.6
6.3
164
1000
4151
FHL
Reoperation for chronic otitis media
66.0
6.3
7
*
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
6.2
519
3903
VALMI
NOMESCO Finland
NA
1.2
6.2
1285
10671
H53.0
ICD-10 Finland
Amblyopia ex anopsia
2.2
6.2
57
244
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
3.7
6.2
25
64
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
6.2
2314
20196
J01FA01
ATC
erythromycin; systemic
1.3
6.2
463
3430
201
Kela drug reimbursment
Chronic cardiac insufficiency
1.9
6.2
78
382
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
6.2
1371
11454
RK320
NOMESCO Finland
NA
4.0
6.2
23
55
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
13.5
6.2
10
7
SGA01
NOMESCO Finland
Tooth opening as first aid
1.3
6.2
503
3771
R51
ICD-10 Finland
Headache
1.5
6.2
196
1249
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.5
6.2
181
1132
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.6
6.2
166
1020
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
6.1
524
3957
4148
FHL
Radical cutting and cavity filling
+∞
6.1
6
*
3811A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic serous otitis media
+∞
6.1
6
*
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
5.0
6.1
18
34
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.4
6.1
285
1959
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.4
6.1
329
2321
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
2.0
6.1
70
329
0601
NOMESCO Finland
NA
17.0
6.1
9
5
R05CB13
ATC
dornase alfa (desoxyribonuclease); inhalant
25.2
6.1
8
*
304
Kela drug reimbursment
Dornase alfa
25.2
6.1
8
*
A12AA04
ATC
calcium carbonate; oral
2.9
6.0
35
116
Z94.2
ICD-10 Finland
Lung transplant status
8.7
6.0
12
13
E66.00
ICD-10 Finland
Metabolic syndrome
1.7
6.0
109
603
A46
ICD-10 Finland
Erysipelas
1.4
6.0
261
1773
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
522
2548
1.98
42.52
8.3
5.2
5.0
5.1
kpa
0.93
490
2412
2493
18241
1.48
41.78
7.9
6.0
2.9
2.8
%
0.36
2344
17069
508
2483
1.98
41.17
8.3
5.3
0.9
1.3
mmol/l
1.59
366
1771
2141
15329
1.48
39.20
9.1
6.5
1.2
1.2
mmol/l
1.65
1847
13089
2591
19265
1.46
38.97
7.8
6.0
31.1
30.7
%
0.86
2439
18096
2659
19977
1.45
37.16
8.3
6.3
0.2
0.2
e9/l
0.78
2363
17599
2539
18966
1.44
36.24
7.6
5.8
54.5
54.9
%
1.08
2402
17858
347
1548
2.14
35.92
9.9
6.2
9.6
9.4
kpa
1.42
329
1477
1955
13935
1.46
35.63
8.9
6.3
1.2
1.2
mmol/l
2.33
1794
12757
2659
20135
1.43
34.59
7.8
5.9
2.1
2.1
e9/l
1.12
2381
17822
2602
19668
1.42
33.93
5.7
4.7
6.4
6.3
mmol/l
0.53
2404
17882
2854
22076
1.41
31.74
9.9
8.4
4.0
3.9
e9/l
0.29
2478
19165
1884
13553
1.43
31.67
2.1
1.8
—
—
—
0
0
387
1889
1.95
31.26
8.9
5.8
24.1
24.3
mmol/l
1.44
380
1828
2165
16008
1.41
30.99
5.9
5.6
11.8
11.8
umol/l
0.00
2044
14942
278
1207
2.18
30.79
14.1
8.5
1.3
1.2
mg/l
0.80
266
1156
3310
26345
1.41
30.70
5.0
3.7
9.5
9.4
mm/h
0.17
3079
24418
1456
10043
1.46
30.40
2.9
2.4
55.0
56.4
u/l
0.28
1355
9265
3201
25365
1.40
30.21
7.5
6.4
82.8
79.2
u/l
3.34
3011
23822
529
2905
1.75
29.29
3.7
2.6
10.1
10.4
g/l
0.86
494
2678
721
4337
1.61
28.21
9.8
6.4
1.1
1.1
mmol/l
1.14
681
4070
1069
7025
1.50
28.16
3.4
2.4
7.6
7.4
e6/l
0.08
944
6150
31
26
11.03
27.93
5.5
7.0
—
—
—
0
0
2327
17666
1.38
27.30
10.6
8.3
0.0
0.0
e9/l
0.04
1920
14259
42
57
6.83
26.27
7.7
7.0
2.7
2.4
mg/l
0.34
36
47
537
3052
1.69
26.15
1.4
1.3
255.6
280.8
u/ml
0.19
500
2808
4371
37013
1.48
25.52
15.1
11.3
3.9
3.9
mmol/l
0.71
4247
35700
4362
36948
1.47
25.16
15.0
11.2
139.6
139.5
mmol/l
0.47
4254
35741
576
3396
1.63
24.25
7.6
5.3
1.4
1.6
mmol/l
0.67
469
2693
578
3416
1.62
24.10
7.6
5.2
5.9
5.8
kpa
1.44
556
3317
389
2102
1.76
22.64
5.9
4.3
68.2
73.9
ng/l
1.00
350
1885
4584
39440
1.49
22.06
14.5
10.5
20.5
21.8
mg/l
1.92
3618
29342
755
4834
1.51
22.03
2.1
1.7
—
—
—
0
0
1406
10113
1.38
21.78
1.6
1.4
2.0
2.1
g/l
0.73
857
6149
31
38
7.55
21.17
4.8
5.2
—
—
—
0
0
31
38
7.55
21.17
5.2
5.3
—
—
—
0
0
1430
10353
1.37
21.16
4.1
3.0
31.1
101.3
e6/l
3.07
1148
7718
412
2308
1.70
21.05
7.6
5.8
23.9
23.9
mmol/l
0.04
385
2178
44
79
5.16
20.88
6.9
6.1
—
—
—
0
0
401
2241
1.70
20.67
2.2
1.8
1.2
1.3
g/l
0.44
378
2098
499
2964
1.61
20.26
7.8
5.1
4.9
4.9
kpa
0.05
484
2878
174
746
2.19
19.94
5.0
3.3
23.7
24.2
mmol/l
0.89
153
672
101
339
2.78
19.60
3.7
3.5
88.0
95.7
%
1.85
96
321
100
334
2.79
19.59
3.1
2.3
—
—
—
0
0
1312
9470
1.36
19.51
4.1
2.9
0.3
0.4
e6/l
0.42
1027
6947
459
2698
1.62
19.43
12.4
8.1
7.5
7.4
mmol/l
0.13
445
2609
32
45
6.58
19.40
1.8
1.7
1.1
3.0
mg/l
1.01
21
34
32
45
6.58
19.40
1.8
1.7
1.6
1.2
mg/l
0.24
19
35
32
45
6.58
19.40
1.8
1.7
1.1
1.6
mg/l
0.40
23
36
32
45
6.58
19.40
1.8
1.7
1.3
0.9
mg/l
0.41
22
31
32
45
6.58
19.40
1.8
1.7
2.7
1.9
mg/l
0.23
20
36
32
45
6.58
19.40
1.8
1.7
1.1
2.4
mg/l
0.63
24
36
32
45
6.58
19.40
1.8
1.7
4.0
4.6
mg/l
0.15
22
34
32
45
6.58
19.40
1.8
1.7
0.7
1.9
mg/l
1.25
20
30
32
45
6.58
19.40
1.8
1.7
3.3
3.8
mg/l
0.14
19
28
1373
9999
1.36
19.24
3.3
2.9
29.1
66.5
ng/l
1.01
739
5211
32
46
6.44
19.01
1.8
1.8
0.9
0.9
mg/l
0.04
20
36
1563
11642
1.33
18.74
4.1
3.2
30.2
32.9
u/l
0.96
1496
11091
1569
11694
1.33
18.73
1.5
1.4
1.5
1.9
u/ml
1.19
381
2957
1068
7500
1.39
18.72
2.5
2.0
1.2
1.1
mg/l
0.27
759
5320
99
341
2.70
18.32
2.9
2.6
0.2
0.2
e9/l
0.44
85
269
770
5127
1.45
18.20
4.2
3.2
237.4
472.5
ng/l
2.82
454
3150
148
621
2.23
17.91
9.0
4.2
366.1
1362.8
u/ml
0.93
19
41
704
4632
1.46
17.68
4.2
2.8
30.2
29.7
s
1.22
680
4488
66
185
3.31
17.49
29.4
25.2
130.0
131.6
ug/l
0.04
57
161
3654
30649
1.31
17.48
4.3
3.7
14.5
14.5
pmol/l
0.06
3343
27674
98
345
2.64
17.40
2.9
2.6
602.0
550.9
e6/l
0.44
84
269
99
351
2.63
17.33
3.1
2.3
9.4
11.5
%
1.24
74
230
625
4034
1.48
17.30
3.1
2.4
21.9
23.3
%
1.94
547
3515
38
71
4.95
17.28
3.9
4.6
—
—
—
0
0
732
4875
1.44
17.22
2.9
2.3
13.7
14.1
umol/l
0.62
691
4552
520
3241
1.53
17.02
2.0
1.6
—
—
—
0
0
1691
12896
1.30
16.69
6.1
4.9
37.0
36.8
g/l
0.70
1590
12011
816
5579
1.41
16.54
1.3
1.2
14.3
9.8
u/ml
0.36
267
2163
700
4657
1.44
16.52
7.9
4.5
0.8
0.8
mmol/l
2.55
657
4375
1086
7784
1.36
16.50
1.7
1.6
1.4
1.3
mmol/l
0.96
928
6767
582
3740
1.49
16.43
4.4
3.3
6.2
6.9
umol/l
0.57
495
3197
666
4397
1.45
16.36
2.9
2.3
2.5
2.5
g/l
1.04
616
4100
1662
12701
1.30
15.99
4.6
3.5
86.8
84.7
e6/l
0.03
1221
8389
521
3296
1.50
15.86
2.1
1.7
—
—
—
0
0
121
493
2.29
15.75
3.1
3.1
22.3
26.1
mu/l
0.62
112
457
1127
8187
1.34
15.55
2.4
2.2
175.7
240.9
u/l
1.14
1072
7760
2998
24714
1.27
15.32
5.1
3.9
2690.6
1428.4
e6/l
0.53
38
319
237
1255
1.77
14.80
3.9
3.6
163.9
168.9
%
0.41
225
1200
1872
14660
1.27
14.47
3.1
2.3
72.0
71.5
nmol/l
0.38
1741
13553
165
789
1.95
14.21
2.2
1.7
—
—
—
0
0
164
785
1.95
14.09
2.3
1.7
—
—
—
0
0
166
800
1.94
13.98
9.7
5.8
815.3
648.8
iu/ml
0.16
27
90
4110
35377
1.30
13.95
5.0
4.3
1.9
1.9
mu/l
0.25
3870
33058
351
2123
1.56
13.12
1.9
1.7
—
—
—
0
0
81
301
2.50
12.99
2.6
2.7
804.3
867.9
e6/l
0.25
24
106
251
1404
1.68
12.91
7.1
4.0
94.3
93.8
%
0.14
240
1310
54
162
3.09
12.91
1.2
1.2
—
—
—
0
0
217
1170
1.74
12.77
1.7
1.8
0.2
0.2
g/l
0.36
206
1117
307
1817
1.59
12.61
4.4
3.0
127.1
161.7
ng/l
1.08
280
1607
3046
25442
1.24
12.59
3.5
2.9
39.0
36.4
u/l
1.22
2878
24093
469
3046
1.46
12.46
3.5
3.0
0.2
0.2
g/l
0.41
447
2840
4572
40095
1.34
12.42
10.4
8.2
26.8
25.9
u/l
1.61
4416
38671
237
1322
1.68
12.33
5.5
3.9
3.5
3.4
g/l
0.77
223
1264
824
5900
1.34
12.25
1.3
1.3
21.8
26.0
iu/ml
0.65
229
1647
219
1199
1.71
12.22
1.7
1.8
1.2
1.2
g/l
0.13
208
1147
2304
18725
1.23
12.16
4.0
3.2
0.0
0.0
estimate
1.32
493
3657
2288
18588
1.23
12.09
3.9
3.2
0.0
0.0
estimate
1.34
489
3626
4055
35043
1.27
11.98
4.1
3.7
—
—
—
0
0
4022
34731
1.27
11.92
17.1
12.9
13.4
13.3
%
0.52
3940
33936
1338
10257
1.27
11.85
2.9
2.9
2.4
2.4
mmol/l
0.08
1218
9150
940
6891
1.31
11.80
3.6
2.5
3948.3
4393.3
umol/l
0.14
827
6107
1195
9053
1.28
11.63
2.4
2.3
2.7
2.7
mg/l
0.47
1052
7757
2282
18587
1.23
11.60
5.4
4.4
0.0
0.0
estimate
0.50
517
3768
546
3705
1.40
11.36
2.7
2.0
364.1
380.2
nmol/l
1.09
519
3412
947
6983
1.30
11.34
4.8
4.1
9.5
12.0
mg/mmol
0.41
634
4665
111
502
2.06
11.25
1.5
1.2
253.3
408.0
titre
—
6
10
144
725
1.85
10.71
1.6
1.2
—
—
—
0
0
144
726
1.85
10.67
1.6
1.2
—
—
—
0
0
113
531
1.98
10.34
2.0
1.5
—
—
—
0
0
808
5901
1.31
10.32
4.1
3.0
957.7
1098.0
ng/l
0.65
664
4846
144
736
1.82
10.23
4.0
3.4
3.9
3.9
e9/l
0.05
144
736
150
779
1.79
10.11
1.5
1.2
—
—
—
0
0
147
759
1.80
10.10
4.5
3.6
56.2
55.5
%
0.30
147
759
1252
9679
1.25
10.05
4.1
3.3
7.9
8.4
mmol/l
2.99
1086
8459
1492
11782
1.23
9.80
1.9
1.8
96.6
96.5
pmol/l
0.01
808
6350
115
559
1.91
9.57
2.4
1.7
—
—
—
0
0
2382
19726
1.20
9.54
3.3
2.8
77.5
80.5
ug/l
0.33
2253
18516
104
489
1.98
9.54
2.3
1.6
—
—
—
0
0
743
5426
1.30
9.45
3.3
2.7
3.9
3.5
e6/l
0.40
429
2794
172
948
1.69
9.44
5.6
5.9
1.7
1.7
%
0.27
162
883
3370
28830
1.21
9.43
5.0
4.2
38.2
37.7
mmol/mol
2.29
3150
27042
88
391
2.09
9.42
2.0
1.5
—
—
—
0
0
768
5645
1.29
9.29
3.2
2.6
1.4
1.1
e6/l
0.70
460
3012
414
2773
1.41
9.28
14.0
18.1
1.2
1.2
inr
0.12
59
457
478
3310
1.36
8.76
4.8
3.3
1.6
1.6
%
0.96
419
2986
232
1406
1.54
8.68
1.8
1.3
—
—
—
0
0
328
2136
1.44
8.61
3.0
2.4
74.1
77.2
ml/min/173m2
0.46
120
796
367
2442
1.41
8.56
3.3
3.3
4.7
4.7
pmol/l
0.00
335
2213
182
1050
1.62
8.41
2.1
1.5
136.4
106.3
u/ml
0.60
36
180
188
1094
1.60
8.39
1.9
1.6
231.1
201.1
titre
—
9
35
208
1240
1.57
8.38
5.9
3.4
24.9
24.9
mmol/l
0.06
197
1191
455
3150
1.36
8.35
5.2
4.4
244.3
246.6
u/l
0.06
437
2999
221
1337
1.54
8.34
1.9
1.3
244.3
206.2
u/ml
1.11
121
737
91
433
1.95
8.13
1.9
1.4
—
—
—
0
0
135
729
1.72
8.04
2.8
2.0
133.9
132.6
g/l
0.21
113
569
835
6311
1.26
7.99
2.7
2.7
126.8
115.5
ug/g
0.33
650
4970
869
6600
1.25
7.97
1.5
1.5
20.2
19.9
nmol/l
0.23
757
5822
388
2640
1.38
7.94
9.7
8.4
1.4
1.4
mmol/l
0.08
368
2504
333
2208
1.41
7.93
1.2
1.1
4.6
3.9
u/ml
—
5
28
316
4005
0.71
7.93
1.5
1.5
—
—
—
0
0
73
328
2.06
7.66
2.1
1.7
—
—
—
0
0
1072
8365
1.22
7.63
5.9
4.2
91.6
91.5
%
0.07
1042
8149
94
465
1.88
7.51
1.6
1.5
—
—
—
0
0
282
1837
1.44
7.43
3.3
2.4
67.0
66.9
g/l
0.07
270
1702
83
396
1.94
7.39
2.1
1.6
—
—
—
0
0
113
599
1.75
7.23
1.3
1.3
—
—
—
0
0
3752
32727
1.19
7.18
3.8
3.4
5.7
5.6
mmol/l
1.02
3476
30206
149
857
1.62
7.04
1.7
1.6
—
—
—
0
0
76
360
1.96
6.94
1.9
1.4
—
—
—
0
0
214
1341
1.49
6.91
2.6
1.5
15.3
13.1
u/ml
0.17
18
56
284
1879
1.41
6.89
1.5
1.5
—
—
—
0
0
1760
14485
1.18
6.88
4.0
3.2
—
—
—
0
0
5018
45180
1.36
6.75
20.3
15.3
7.0
6.8
e9/l
4.64
4887
43707
116
634
1.70
6.69
3.3
2.2
17.8
17.0
%
1.50
73
291
230
1472
1.46
6.69
1.3
1.3
—
—
—
0
0
82
404
1.88
6.68
2.4
1.6
—
—
—
0
0
5018
45187
1.36
6.67
20.5
15.3
136.1
135.6
g/l
1.60
4952
44538
258
1688
1.43
6.67
1.8
1.7
—
—
—
0
0
89
451
1.83
6.64
3.8
3.1
1.0
1.4
%
0.72
72
357
5015
45159
1.36
6.64
20.3
15.2
4.6
4.6
e12/l
3.47
4877
43692
126
706
1.66
6.62
1.2
1.3
18.2
3.1
u/ml
—
8
52
5009
45100
1.35
6.60
20.3
15.3
261.8
260.1
e9/l
1.08
4884
43733
44
171
2.38
6.60
1.1
1.1
93.2
92.3
%
0.10
23
82
778
5964
1.23
6.49
1.6
1.6
45950596.9
27506348.1
pmol/l
0.35
642
5068
3746
32775
1.17
6.46
11.1
9.2
96.4
95.0
ml/min/173m2
2.77
3021
25551
123
690
1.66
6.45
1.5
1.4
—
—
—
0
0
129
733
1.64
6.43
5.5
4.0
5.0
5.0
kpa
0.15
129
719
50
210
2.20
6.29
1.8
1.9
0.2
0.1
nmol/l
1.07
35
163
53
228
2.15
6.29
1.7
1.6
—
—
—
0
0
53
228
2.15
6.29
1.7
1.6
—
—
—
0
0
53
228
2.15
6.29
1.7
1.6
—
—
—
0
0
337
2340
1.35
6.11
5.0
3.3
1.2
1.2
mmol/l
0.13
291
2007
220
1422
1.44
6.10
1.2
1.2
1.1
0.9
u/ml
0.09
12
107
42
166
2.34
6.09
1.2
1.3
88.0
90.6
%
0.16
23
82
74
364
1.88
6.09
2.0
6.6
7.0
7.0
mmol/l
0.04
58
287
20
53
3.48
5.94
4.1
1.7
—
—
—
0
0
213
1377
1.44
5.91
13.1
11.8
—
—
—
0
0
256
1712
1.40
5.88
6.0
4.7
130.2
131.2
g/l
0.29
244
1671
65
310
1.94
5.88
1.5
1.2
0.4
0.8
u/ml
0.40
26
95
159
972
1.52
5.84
2.0
1.7
271.5
4823.2
e6/l
0.62
129
768
150
906
1.54
5.82
1.2
1.3
7.8
14.6
u/ml
0.97
20
145
148
897
1.53
5.66
1.2
1.3
3.6
6.8
u/ml
0.49
12
94
158
972
1.51
5.64
1.9
1.7
21.9
19.6
e6/l
0.05
117
733
352
2494
1.32
5.59
1.7
1.5
13.3
17.6
iu/l
3.53
296
2013
614
4662
1.24
5.58
1.7
1.6
1118.9
1158.7
nmol/l
0.47
474
3550
44
185
2.20
5.56
3.3
2.8
34.5
44.3
%
2.09
18
59
1246
10116
1.17
5.55
4.2
3.4
0.0
0.0
estimate
1.91
498
3644
172
1081
1.48
5.55
1.9
1.6
617.4
449.1
mg/l
0.51
160
1021
244
1637
1.39
5.52
1.6
1.6
—
—
—
0
0
44
188
2.16
5.36
1.7
1.9
129.6
138.1
%
0.35
44
178
354
2527
1.31
5.34
2.4
2.3
12.7
20.4
au/ml
1.64
28
185
431
3159
1.28
5.31
2.6
2.3
28.0
35.5
u/l
3.70
365
2695
301
2105
1.33
5.25
1.8
1.6
7.4
8.1
u/l
0.67
248
1650
1994
16822
1.15
5.23
4.3
3.9
—
—
—
0
0
214
1418
1.41
5.22
1.2
1.2
—
—
—
0
0
401
2923
1.28
5.17
3.2
2.9
—
—
—
0
0
4372
38950
1.18
5.14
15.2
11.4
40.1
40.1
%
0.10
3451
31556
447
3306
1.27
5.12
1.0
1.1
—
—
—
0
0
327
2331
1.31
5.00
1.3
1.3
27.6
42.7
au/ml
—
10
84
118
703
1.56
4.93
2.8
3.2
34.7
35.1
umol/l
0.07
107
617
88
490
1.66
4.85
1.2
1.2
4.6
8.4
u/ml
0.43
48
208
23
77
2.76
4.72
6.2
3.6
—
—
—
0
0
70
369
1.76
4.70
1.7
1.4
—
—
—
0
0
21
68
2.85
4.58
1.3
1.4
—
—
—
0
0
174
1140
1.42
4.58
3.0
2.8
6.8
6.8
umol/l
0.01
128
892
43
195
2.04
4.55
1.4
1.1
—
—
—
0
0
3776
33366
1.14
4.55
4.1
3.6
2.8
2.8
mmol/l
0.20
3522
31204
151
966
1.45
4.52
1.9
1.6
3.8
3.6
mmol/l
1.35
142
897
10
19
4.85
4.50
3.1
2.8
4.2
4.4
mmol/l
—
10
19
35
148
2.18
4.43
1.3
1.2
107.9
106.3
%
0.11
30
132
90
519
1.61
4.36
1.2
1.2
—
—
—
0
0
132
829
1.48
4.36
1.5
1.4
300.2
310.6
ug/g
0.21
76
419
73
399
1.69
4.35
1.3
1.2
—
—
—
0
0
136
860
1.47
4.34
2.3
2.0
1.4
1.9
ug/l
0.25
119
764
153
990
1.43
4.33
1.2
1.3
13.9
36.4
u/ml
—
8
57
390
2901
1.26
4.29
2.0
1.9
—
—
—
0
0
39
175
2.06
4.27
3.2
2.2
683.2
594.2
ml
0.88
31
120
12
28
3.95
4.26
1.7
1.4
134.0
99.6
ng/l
0.33
12
28
38
169
2.08
4.26
1.3
1.2
—
—
—
0
0
70
381
1.70
4.24
1.2
1.1
8.9
6.4
iu/ml
0.26
15
88
32
133
2.22
4.24
1.6
1.9
—
—
—
0
0
32
133
2.22
4.24
1.6
1.9
—
—
—
0
0
32
133
2.22
4.24
1.6
1.9
—
—
—
0
0
32
133
2.22
4.24
1.6
1.9
—
—
—
0
0
3746
33141
1.13
4.23
3.9
3.4
4.5
4.6
mmol/l
4.09
3528
31217
378
2808
1.26
4.21
9.6
8.4
13.0
13.4
kpa
0.66
358
2694
378
2808
1.26
4.21
9.7
8.4
5.2
5.0
kpa
1.42
357
2693
550
4257
1.21
4.17
2.7
2.4
7442.3
6921.0
u/l
0.10
199
1566
53
268
1.83
4.13
3.4
3.0
54.6
53.7
%
0.08
37
179
69
379
1.68
4.06
1.6
1.5
308.6
394.8
pmol/l
0.80
50
303
144
935
1.43
4.03
1.1
1.1
28.1
11.8
au/ml
—
6
69
59
311
1.75
4.02
1.6
1.2
—
—
—
0
0
101
611
1.53
4.01
5.2
5.2
422.8
379.0
umol/l
1.56
90
539
22
79
2.57
3.99
1.2
1.1
—
—
—
0
0
59
312
1.75
3.98
1.6
1.2
—
—
—
0
0
113
703
1.49
3.94
1.3
1.2
—
—
—
0
0
194
1331
1.35
3.92
13.3
11.4
24.2
24.1
mmol/l
0.21
183
1273
3702
32803
1.13
3.83
3.8
3.3
1.4
1.5
mmol/l
13.30
3468
30763
117
738
1.47
3.83
2.6
2.7
—
—
—
0
0
377
2836
1.24
3.79
1.6
1.6
324.5
337.7
mu/l
0.31
328
2554
26
104
2.31
3.78
1.7
2.0
—
—
—
0
0
26
104
2.31
3.78
1.7
2.0
—
—
—
0
0
35
159
2.03
3.75
2.4
1.5
—
—
—
0
0
60
327
1.70
3.67
1.1
1.2
—
57.0
—
0
5
371
2799
1.24
3.64
9.8
8.4
1.2
0.8
mmol/l
1.02
281
2115
45
228
1.82
3.53
2.8
2.7
60.2
55.5
umol/l
0.37
37
199
167
1143
1.36
3.47
2.3
2.0
—
—
—
0
0
3557
31520
1.12
3.46
3.5
3.1
1.3
1.2
mmol/l
4.37
3334
29540
31
140
2.04
3.40
1.3
1.4
—
—
—
0
0
22
86
2.36
3.39
3.3
2.1
—
—
—
0
0
68
394
1.60
3.32
1.8
1.6
—
—
titre
—
0
0
26
111
2.16
3.29
1.8
2.0
—
—
—
0
0
43
221
1.80
3.25
1.1
1.0
—
—
—
0
0
121
795
1.41
3.24
1.2
1.2
79.7
36.0
u/ml
—
5
61
36
175
1.90
3.23
1.9
1.7
—
—
—
0
0
31
143
2.00
3.23
1.3
1.4
—
—
—
0
0
454
3541
1.20
3.21
1.3
1.2
111.5
137.1
iu/ml
0.79
166
1281
30
137
2.02
3.21
2.6
1.5
—
—
—
0
0
181
1271
1.32
3.20
2.0
1.8
—
—
—
0
0
199
1419
1.30
3.16
1.1
1.1
20.0
4.4
u/ml
0.69
18
187
19
72
2.43
3.14
2.2
1.2
—
—
—
0
0
34
164
1.91
3.13
7.4
5.5
101.7
2295.1
mg/l
0.78
29
125
63
364
1.60
3.13
2.1
1.8
—
—
—
0
0
983
8150
1.13
3.13
2.6
2.2
—
—
—
0
0
107
693
1.43
3.12
2.3
2.4
0.9
0.7
nmol/l
1.98
93
599
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
26
114
2.10
3.10
1.1
1.1
57.3
71.4
%
—
6
27
191
1361
1.30
3.06
1.5
1.3
—
—
—
0
0
434
3388
1.19
3.05
8.1
7.4
104.9
104.8
mmol/l
0.17
428
3320
42
219
1.77
3.05
2.3
1.5
—
—
—
0
0
25
109
2.12
3.03
2.2
3.2
—
—
—
0
0
204
1471
1.29
2.99
1.2
1.1
3.0
3.5
u/ml
0.15
70
439
67
398
1.56
2.98
1.2
1.7
—
—
—
0
0
26
116
2.07
2.97
1.1
1.1
68.8
82.6
%
—
6
29
25
110
2.10
2.96
1.2
1.1
—
—
—
0
0
160
1118
1.33
2.96
1.2
1.1
—
—
—
0
0
104
678
1.42
2.94
2.6
2.2
1.1
0.8
g/l
0.16
95
607
159
1112
1.33
2.92
1.2
1.1
—
—
—
0
0
210
1526
1.28
2.91
1.2
1.1
6.4
7.3
u/ml
0.34
135
948
32
156
1.89
2.88
2.8
2.4
1.8
1.7
mmol/l
0.11
26
116
47
258
1.68
2.87
1.1
1.1
—
—
—
0
0
760
6233
1.14
2.86
1.8
1.7
1.4
1.4
%
0.10
674
5642
416
3257
1.19
2.85
3.7
3.5
31.5
32.4
%
0.93
322
2317
48
266
1.67
2.84
1.3
1.2
155.6
77.5
u/l
0.40
36
197
30
144
1.92
2.83
1.2
1.2
—
—
—
0
0
29
138
1.94
2.81
2.7
1.5
—
—
—
0
0
200
1452
1.28
2.80
1.2
1.1
1.6
1.4
u/ml
0.11
117
771
184
1330
1.28
2.68
1.8
1.9
38.1
39.5
u/l
0.44
170
1225
33
167
1.82
2.67
1.4
1.2
0.3
0.3
g/l
0.22
24
132
97
637
1.41
2.67
2.1
1.7
—
—
—
0
0
225
1675
1.25
2.58
1.3
1.1
2.5
2.5
u/ml
0.01
132
850
9
23
3.61
2.54
1.0
1.2
—
—
—
0
0
148
1048
1.31
2.54
1.2
1.1
10.7
8.7
u/ml
0.25
84
521
140
984
1.32
2.53
2.1
1.9
4.6
4.3
iu/l
0.17
55
380
36
191
1.74
2.52
1.0
1.0
-0.5
-2.0
mmol/l
—
7
48
19
81
2.16
2.47
1.8
1.6
—
—
—
0
0
356
2792
1.19
2.43
2.4
2.1
10.0
11.2
nmol/l
1.84
308
2481
181
1324
1.27
2.43
5.4
4.6
0.7
0.7
%
2.12
172
1288
68
426
1.48
2.43
1.3
1.3
13.2
0.5
nmol/l
0.49
63
409
115
792
1.34
2.41
1.1
1.1
—
—
—
0
0
139
1648
0.77
2.40
1.3
1.4
—
—
—
0
0
32
167
1.77
2.38
1.6
1.6
7.9
6.4
u/l
0.19
21
93
114
786
1.34
2.37
2.8
2.1
7.2
7.4
g/l
0.63
95
609
114
786
1.34
2.37
2.8
2.1
—
—
—
0
0
114
786
1.34
2.37
2.8
2.1
3.5
3.8
g/l
1.56
89
577
57
348
1.51
2.32
1.2
1.1
—
—
—
0
0
23
110
1.93
2.24
1.3
1.4
—
—
—
0
0
23
110
1.93
2.24
1.3
1.4
—
—
—
0
0
935
7884
1.11
2.22
2.2
2.2
—
—
—
0
0
35
192
1.68
2.21
2.9
2.5
645.7
1239.5
u/ml
1.58
35
192
108
748
1.34
2.21
2.9
2.1
3.1
3.1
g/l
0.25
91
596
92
622
1.37
2.20
2.8
2.0
39.4
38.2
g/l
1.31
86
547
62
391
1.46
2.18
1.7
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
107
742
1.33
2.17
13.0
5.7
0.3
0.3
u/ml
0.13
71
419
89
600
1.37
2.17
1.1
1.1
118.3
115.6
%
0.37
82
535
46
273
1.56
2.14
1.3
1.2
16.0
9.2
u/ml
0.41
35
205
101
696
1.34
2.14
1.2
1.1
50.4
729.0
iu/ml
0.62
25
215
62
393
1.46
2.13
1.7
1.5
—
—
—
0
0
6
13
4.25
2.11
4.3
3.3
—
—
—
0
0
62
394
1.45
2.11
1.7
1.5
—
—
—
0
0
62
394
1.45
2.11
1.7
1.5
—
—
—
0
0
21
100
1.94
2.09
2.1
2.7
26.5
29.0
umol/l
0.47
12
75
1022
8687
1.10
2.08
3.7
3.2
1.0
1.0
kg/l
0.47
173
1262
105
732
1.33
2.07
2.6
2.1
10.5
10.3
g/l
0.11
97
631
73
480
1.41
2.07
1.1
1.1
—
1.8
—
0
5
21
101
1.92
2.04
1.0
1.0
0.7
3.5
u/ml
1.32
13
70
91
626
1.34
1.98
1.3
1.3
4.3
4.9
u/ml
0.21
44
290
61
393
1.43
1.95
1.7
1.5
—
—
—
0
0
37
214
1.60
1.95
2.1
1.2
—
—
—
0
0
24
123
1.80
1.94
1.0
1.0
0.3
0.1
u/ml
0.22
15
80
62
402
1.42
1.92
1.7
1.5
—
—
—
0
0
303
3230
0.86
1.91
3.0
2.7
0.8
0.7
ug/l
0.13
183
1959
14
59
2.19
1.91
1.9
1.2
24.5
71.3
ng/l
—
8
30
159
1184
1.24
1.90
1.7
2.0
1.4
1.4
g/l
0.16
139
1039
63
412
1.41
1.87
1.9
1.6
1.2
1.3
promille
0.38
50
310
1336
11552
1.09
1.85
2.4
2.3
—
—
—
0
0
154
1147
1.24
1.85
2.0
1.7
—
—
—
0
0
155
1157
1.24
1.83
1.2
1.1
5.8
6.0
u/ml
0.04
89
534
5
11
4.19
1.81
6.2
12.0
—
—
—
0
0
245
1917
1.18
1.79
2.0
2.3
5.9
6.4
ug/l
0.18
206
1686
10
37
2.49
1.79
2.3
1.8
—
—
—
0
0
307
3244
0.86
1.74
1.4
1.4
—
—
—
0
0
163
1817
0.82
1.73
1.5
1.5
3.4
3.9
mg/l
0.41
125
1185
41
251
1.51
1.72
1.3
1.3
1.7
1.4
nmol/l
1.01
35
230
131
971
1.25
1.67
2.3
2.6
221.4
463.1
ug/l
2.10
116
886
29
165
1.62
1.66
1.8
1.9
—
—
—
0
0
40
247
1.49
1.63
2.3
2.4
—
—
—
0
0
29
167
1.60
1.60
1.2
1.2
—
—
—
0
0
46
294
1.44
1.59
2.7
4.6
8.9
8.8
mg/l
0.04
33
249
34
204
1.54
1.58
5.7
3.4
—
—
—
0
0
60
403
1.37
1.58
1.1
1.1
—
—
—
0
0
91
651
1.29
1.57
1.3
1.3
3.0
4.2
u/ml
0.38
30
226
178
1373
1.20
1.57
1.7
1.6
0.0
0.2
iu/ml
1.38
37
283
47
303
1.43
1.56
1.7
1.6
47.9
54.8
%
0.63
37
203
113
832
1.26
1.55
1.7
2.0
9.1
10.4
mg/l
1.30
106
783
79
556
1.31
1.54
3.3
2.4
160.5
99.0
ug/min
0.41
60
352
287
2314
1.15
1.49
10.3
9.0
125.3
123.0
g/l
1.07
272
2237
1430
12497
1.07
1.49
2.6
2.5
—
—
—
0
0
43
276
1.44
1.47
1.2
1.1
1.0
1.1
ratio
1.29
15
107
92
666
1.28
1.47
1.1
1.1
—
—
—
0
0
29
172
1.55
1.44
1.0
1.2
—
—
—
0
0
6
20
2.76
1.44
4.0
2.4
—
—
—
0
0
25
143
1.61
1.43
1.1
1.1
0.2
1.3
u/ml
0.84
19
75
150
1151
1.21
1.42
1.5
1.6
—
—
—
0
0
773
6607
1.09
1.42
2.1
2.0
—
—
—
0
0
20
109
1.69
1.38
3.1
2.0
5.4
2.8
nmol/l
0.32
20
102
15
75
1.84
1.36
2.3
1.7
—
—
—
0
0
49
328
1.38
1.35
2.2
1.9
26.3
26.3
mg/l
0.00
16
93
35
221
1.46
1.32
1.3
1.3
40082.7
59094.8
e6/l
0.24
20
154
434
4398
0.90
1.32
4.0
3.7
22.4
21.1
%
0.82
177
1862
5
16
2.88
1.31
1.0
1.2
0.2
0.2
g/l
—
5
10
81
587
1.27
1.31
1.7
1.7
14787.8
12347.6
e6/l
0.14
58
435
61
426
1.32
1.30
1.1
1.2
27.0
38.5
mg/l
2.81
54
339
41
269
1.41
1.28
1.4
1.5
5.1
6.2
ug/l
0.66
35
237
203
2151
0.86
1.27
1.5
1.5
—
—
—
0
0
24
141
1.57
1.26
1.1
1.1
0.3
5.1
u/ml
0.72
16
75
28
171
1.51
1.25
6.6
5.3
345.5
131.7
u/ml
—
8
32
119
908
1.21
1.23
1.1
1.1
0.9
0.3
u/ml
0.51
45
250
6
23
2.40
1.23
1.0
1.2
—
—
—
0
0
6
23
2.40
1.23
1.5
1.7
40.2
46.2
umol/l
—
6
23
32
202
1.46
1.23
1.1
1.1
11.2
3.6
nmol/l
—
7
39
22
128
1.58
1.21
4.4
3.1
—
—
—
0
0
12
58
1.91
1.21
1.2
1.1
—
—
—
0
0
410
3433
1.11
1.19
1.3
1.3
—
—
—
0
0
13
65
1.84
1.19
1.5
1.1
—
—
—
0
0
187
1490
1.16
1.19
6.5
7.0
25.2
24.1
mmol/l
3.22
169
1397
39
258
1.39
1.18
1.3
1.1
—
—
—
0
0
35
227
1.42
1.18
1.2
1.2
—
—
—
0
0
5
18
2.56
1.17
1.8
3.0
—
—
—
0
0
47
322
1.35
1.16
1.1
1.2
—
—
—
0
0
47
322
1.35
1.16
1.1
1.2
—
—
—
0
0
30
190
1.46
1.15
1.9
1.6
6.8
7.3
u/l
0.11
24
157
47
323
1.34
1.14
1.1
1.2
—
—
—
0
0
14
73
1.77
1.14
1.4
1.5
15.4
15.5
nmol/l
—
7
17
47
324
1.34
1.12
1.1
1.2
—
—
—
0
0
38
253
1.39
1.12
3.2
3.6
161.6
175.2
umol/l
0.11
24
145
47
325
1.33
1.10
1.1
1.2
—
—
—
0
0
11
54
1.88
1.07
1.9
1.9
—
—
—
0
0
73
539
1.25
1.06
1.2
1.2
—
—
—
0
0
15
83
1.67
1.02
1.1
1.0
—
—
—
0
0
14
76
1.70
1.01
1.0
1.1
0.0
0.0
u/ml
—
8
40
52
371
1.29
1.00
1.4
1.4
192.5
272.4
titre
0.32
12
85
39
267
1.35
1.00
2.2
3.8
211.0
79.6
au/ml
—
9
40
75
561
1.23
0.99
5.3
3.1
47.0
65.6
mg/l
0.50
58
458
112
872
1.19
0.99
1.2
1.1
—
—
—
0
0
26
166
1.44
0.98
2.7
2.3
133.0
96.6
umol/l
—
6
26
38
260
1.35
0.98
1.0
1.1
1.0
1.0
u/l
0.69
21
112
64
471
1.25
0.98
1.0
1.1
—
—
—
0
0
11
56
1.81
0.98
1.0
1.0
—
—
—
0
0
18
106
1.56
0.98
1.1
1.1
8.2
13.3
u/ml
0.63
12
69
12
63
1.75
0.97
1.1
1.1
0.4
0.7
umol/24h
—
6
39
75
563
1.23
0.96
5.3
3.1
35.4
50.1
mg/l
0.52
58
461
29
191
1.40
0.94
1.3
1.2
—
—
—
0
0
102
794
1.19
0.92
1.0
1.1
4.3
3.0
u/ml
0.30
38
348
35
240
1.34
0.90
1.4
1.7
—
—
—
0
0
24
154
1.44
0.90
1.0
1.1
—
—
—
0
0
12
65
1.70
0.89
1.2
1.3
—
—
—
0
0
8
40
1.84
0.86
1.0
1.1
—
—
—
0
0
492
4846
0.93
0.86
1.5
1.5
—
—
—
0
0
13
73
1.64
0.86
1.0
1.0
—
—
—
0
0
38
268
1.31
0.83
1.3
1.1
1459.7
1450.5
miu/ml
0.02
38
268
72
549
1.21
0.83
5.4
3.1
2.3
1.7
ratio
—
9
46
32
221
1.33
0.81
1.2
1.7
—
—
—
0
0
11
60
1.69
0.80
1.0
1.0
—
—
—
0
0
16
97
1.52
0.79
1.1
1.1
—
—
—
0
0
0
22
0.00
0.79
0.0
1.3
—
12.6
—
0
22
563
4881
1.07
0.79
2.3
2.7
2.4
2.4
mmol/l
0.63
485
4248
198
2020
0.90
0.77
3.2
4.1
13.3
36.9
ug/l
0.68
140
1564
50
370
1.25
0.77
1.3
1.3
44.6
36.7
u/l
0.11
44
324
40
288
1.28
0.77
1.7
1.5
—
—
—
0
0
68
745
0.84
0.73
1.6
1.6
7.2
7.3
mmol/l
0.15
37
449
289
2455
1.09
0.71
1.4
1.3
209.7
228.1
miu/ml
0.39
143
1191
5
24
1.92
0.70
1.2
1.3
—
—
—
0
0
13
78
1.54
0.69
1.0
1.1
—
—
—
0
0
880
7772
1.05
0.67
1.5
1.5
—
—
—
0
0
15
94
1.47
0.66
1.1
1.2
—
—
—
0
0
29
205
1.30
0.66
2.3
1.6
3.8
3.3
nmol/l
0.08
24
163
13
79
1.52
0.65
6.0
6.7
—
—
—
0
0
16
102
1.45
0.65
1.1
1.1
—
—
—
0
0
119
1231
0.89
0.63
1.2
1.2
—
—
—
0
0
141
1166
1.12
0.62
1.3
1.3
4.0
4.6
ug/l
0.72
132
1112
19
127
1.38
0.62
1.1
1.1
0.1
0.7
u/ml
1.20
11
76
30
216
1.28
0.61
1.0
1.1
262.6
198.8
iu/ml
0.60
30
216
10
58
1.59
0.61
2.0
1.3
—
—
—
0
0
33
241
1.26
0.60
1.0
1.2
—
—
—
0
0
8
48
1.53
0.59
1.0
1.2
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
34
251
1.25
0.58
1.0
1.1
—
—
—
0
0
74
784
0.87
0.57
3.1
3.5
1873.1
1729.7
u/ml
0.02
64
668
249
2465
0.93
0.56
1.4
1.5
—
—
—
0
0
20
138
1.34
0.55
1.8
1.9
54.1
166.8
ug/min
—
7
32
244
2414
0.93
0.55
1.7
1.6
—
—
—
0
0
236
2334
0.93
0.53
1.9
1.8
—
—
—
0
0
228
2244
0.93
0.47
1.4
1.4
—
—
—
0
0
94
777
1.12
0.46
1.5
1.4
10.7
15.7
u/l
2.10
86
676
5
79
0.58
0.45
2.0
2.3
—
—
—
0
0
5
79
0.58
0.45
2.0
2.3
—
—
—
0
0
229
2249
0.93
0.45
1.4
1.4
—
—
—
0
0
25
185
1.24
0.44
3.6
2.0
—
—
—
0
0
25
185
1.24
0.44
3.6
2.0
—
—
—
0
0
229
2246
0.94
0.44
1.4
1.4
—
—
—
0
0
37
402
0.85
0.43
3.8
3.9
217.1
994.5
u/ml
0.64
30
377
5
30
1.53
0.41
1.4
1.3
1.4
1.3
mg/l
—
5
25
0
16
0.00
0.40
0.0
1.0
—
—
—
0
0
5
31
1.48
0.40
1.0
1.1
—
—
—
0
0
229
2238
0.94
0.40
1.4
1.4
—
—
—
0
0
30
231
1.20
0.38
1.6
1.5
38.5
38.1
%
0.02
25
151
29
318
0.84
0.38
2.9
3.1
0.7
0.8
nmol/l
0.65
21
253
5
34
1.35
0.37
1.0
1.1
—
—
—
0
0
27
207
1.20
0.36
1.1
1.1
89.1
91.1
%
0.11
22
162
6
39
1.42
0.35
1.0
1.1
1.3
1.5
umol/24h
—
6
39
6
41
1.35
0.34
1.0
1.1
—
—
—
0
0
6
41
1.35
0.34
1.0
1.2
—
—
—
0
0
12
84
1.32
0.33
1.2
1.1
—
—
—
0
0
44
357
1.14
0.32
2.0
2.4
—
—
—
0
0
7
49
1.32
0.30
1.1
1.1
—
—
—
0
0
7
49
1.32
0.30
1.4
3.4
26.7
44.0
umol/l
—
7
39
19
144
1.22
0.30
1.5
1.5
16.7
13.0
u/l
1.00
19
139
60
609
0.91
0.29
4.2
2.0
13.3
13.0
%
2.40
60
603
22
170
1.19
0.29
1.5
1.6
—
—
—
0
0
7
52
1.24
0.29
1.1
1.2
—
—
—
0
0
7
52
1.24
0.29
1.1
1.2
—
—
—
0
0
11
78
1.30
0.28
2.4
1.3
—
—
—
0
0
62
520
1.10
0.27
1.8
1.6
—
—
—
0
0
20
155
1.19
0.26
2.0
2.2
15.3
16.0
umol/l
0.11
20
155
592
5588
0.97
0.26
4.6
4.2
1.7
2.3
ug/l
2.14
532
5029
143
1245
1.06
0.26
2.0
1.6
38.2
40.0
nmol/l
0.33
143
1222
17
187
0.84
0.25
1.5
1.4
19157.1
114323.6
e6/l
—
7
107
17
130
1.20
0.25
2.0
2.6
—
—
—
0
0
46
382
1.11
0.25
4.1
4.4
491.7
125.9
u/ml
—
9
121
11
127
0.80
0.25
1.1
1.1
—
—
—
0
0
74
632
1.08
0.23
1.6
1.4
—
—
—
0
0
359
3408
0.97
0.23
4.9
5.3
—
—
—
0
0
65
647
0.92
0.23
1.7
1.5
—
—
—
0
0
5
35
1.32
0.23
1.6
2.1
0.8
0.9
u/field
—
5
35
5
35
1.32
0.23
1.2
1.0
—
—
—
0
0
17
184
0.85
0.22
1.2
1.3
6.9
6.4
mmol/l
0.33
17
169
5
37
1.24
0.22
5.8
8.5
5.6
6.5
mmol/l
—
5
37
5
37
1.24
0.22
1.0
1.1
—
—
—
0
0
20
213
0.86
0.22
1.4
1.4
2078.2
2404.2
e6/l
0.11
12
146
5
38
1.21
0.22
1.6
1.3
5.6
23.0
%
—
5
29
54
457
1.09
0.22
1.1
1.1
—
—
—
0
0
16
124
1.19
0.21
1.4
1.4
6.8
5.8
%
—
8
31
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
1.8
—
0
5
0
11
0.00
0.21
0.0
4.6
—
0.2
—
0
11
0
11
0.00
0.21
0.0
1.3
—
2.8
—
0
11
13
99
1.21
0.20
1.3
1.1
—
—
—
0
0
11
82
1.24
0.20
1.0
1.1
—
—
—
0
0
6
44
1.26
0.20
1.0
1.0
—
—
—
0
0
12
133
0.83
0.20
1.1
1.1
—
—
—
0
0
16
172
0.86
0.20
1.0
1.1
—
—
—
0
0
6
46
1.20
0.19
4.2
2.1
—
—
—
0
0
38
318
1.10
0.19
1.1
1.0
—
—
—
0
0
12
91
1.21
0.19
1.0
1.0
166.6
163.0
g/l
0.26
12
91
116
1019
1.05
0.18
1.8
1.5
0.2
0.4
nmol/l
3.11
86
839
15
118
1.17
0.17
1.0
1.0
916.8
706.8
ng/l
—
10
72
74
643
1.06
0.17
1.2
1.2
—
—
—
0
0
18
188
0.88
0.16
1.6
2.3
163.4
146.9
nmol/l
0.20
13
168
15
120
1.15
0.15
1.0
1.0
340.1
275.4
ng/l
—
10
76
80
773
0.95
0.14
3.7
3.0
22.4
25.8
mg/l
0.50
51
481
7
83
0.78
0.14
3.6
2.4
—
—
—
0
0
38
376
0.93
0.14
1.6
1.4
—
—
—
0
0
75
660
1.05
0.12
1.6
1.5
6.5
6.7
mmol/l
0.13
53
466
26
220
1.09
0.12
1.7
1.7
—
—
—
0
0
47
410
1.06
0.10
1.3
1.4
28.4
32.0
nmol/l
0.36
40
373
5
41
1.12
0.10
2.2
1.5
—
—
—
0
0
5
41
1.12
0.10
1.6
1.2
1.9
1.7
ml/s/173m2
—
5
32
5
42
1.10
0.09
2.2
2.5
—
—
—
0
0
5
43
1.07
0.09
1.0
1.1
—
—
—
0
0
28
241
1.07
0.09
1.3
1.3
—
—
—
0
0
24
206
1.07
0.08
1.6
2.1
3.8
1.9
u/field
1.03
16
105
7
63
1.02
0.07
1.1
1.1
—
—
—
0
0
13
132
0.91
0.07
1.1
1.1
—
—
—
0
0
6
69
0.80
0.07
1.2
1.3
—
—
—
0
0
176
1646
0.98
0.06
1.9
2.7
25.2
40.9
u/ml
2.45
165
1594
43
409
0.97
0.05
1.9
2.3
—
—
—
0
0
145
1353
0.99
0.04
1.7
1.5
—
—
—
0
0
196
1786
1.01
0.04
1.4
1.4
—
—
—
0
0
72
675
0.98
0.03
1.7
2.2
—
—
—
0
0
86
779
1.02
0.03
1.4
1.4
51.5
118.5
pmol/l
2.36
80
757
233
2128
1.01
0.03
2.0
2.0
—
—
—
0
0
51
480
0.98
0.03
1.4
1.4
11.3
11.4
mmol/l
—
10
72
10
99
0.93
0.02
1.7
1.4
12.3
9.4
ug/l
—
10
99
146
1334
1.01
0.01
1.9
1.9
—
—
—
0
0
13
126
0.95
0.01
1.1
1.1
—
—
—
0
0
10
98
0.94
0.01
1.1
1.1
—
—
—
0
0
13
124
0.96
0.00
1.1
1.1
—
—
—
0
0
11
99
1.02
0.00
1.2
1.3
71.5
139.3
nmol/l
—
6
71
18
166
1.00
0.00
1.1
1.1
97.8
227.8
ng/l
—
5
32
14
129
1.00
0.00
1.0
1.1
—
—
—
0
0
83
759
1.01
0.00
1.8
1.6
4288.0
1422.9
titre
—
5
14
44
404
1.00
0.00
1.2
1.2
—
—
—
0
0
31
282
1.01
0.00
1.5
1.3
94.0
159.8
pmol/l
—
9
84
8
82
0.90
0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
1.0
—
0
5
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
60.3
—
0
6
7
69
0.93
0.00
2.0
1.9
—
—
—
0
0
5
54
0.85
0.00
1.0
1.0
0.5
0.2
u/ml
—
5
44
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
82
0.90
0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
1.1
—
0
7
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
81
0.91
0.00
1.1
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_OTIMEDNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_OTIMEDNAS | 1.432 [1.19, 1.72] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.226 |
During the follow-up period (1.1.1998 — 31.12.2019), 1155 out of 59246 females with H8_OTIMEDNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_OTIMEDNAS | 1.551 [1.2, 2.01] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 1256 out of 71952 males with H8_OTIMEDNAS died.
Mortality risk
Mortality risk for people of age
years, who have H8_OTIMEDNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.138% | 0.314% |
| 5 | 0.738% | 1.785% |
| 10 | 2.034% | 4.318% |
| 15 | 3.894% | 8.33% |
| 20 | 7.097% | 14.033% |
Relationships between endpoints
↥Index endpoint: H8_OTIMEDNAS – Otitis media, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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