uterine corpus cancer: A uterine cancer that is located_in the uterine corpus.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
164 |
4. Check minimum number of eventsNone |
164 |
5. Include endpointsNone |
164 |
6. Filter based on genotype QC (FinnGen only) |
160 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D10
- Name in latin
- Neoplasma benignum hypopharyngis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Hypopharynx
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of mouth and pharynx
- Benign neoplasms
- Neoplasms
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 787 | 363 | 414 |
| Only index persons | 644 | 303 | 341 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 59.62 | 57.19 | 61.60 |
| Only index persons | 59.07 | 56.24 | 61.58 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 160 | 63 | 97 |
| Unadjusted period prevalence (%) | 0.04 | 0.02 | 0.04 |
| Median age at first event (years) | 58.73 | 49.74 | 64.57 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 164
- Matched controls
- 1640
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D10.7
ICD-10 Finland
Benign neoplasm: Hypopharynx
+∞
187.4
142
*
UJC01
NOMESCO Finland
Scopy of lower throat
91.6
109.4
59
10
JDB10
NOMESCO Finland
Percutaneous gastrostomy
48.9
29.4
35
9
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
35.0
28.1
36
13
WF002
NOMESCO Finland
Radical radiotherapy
7.7
22.5
36
58
130
Kela drug reimbursment
Malignant tumour
5.7
20.6
47
108
DQB10
NOMESCO Finland
Endoscopic excision of lesion of larynx
50.4
18.8
22
5
UDQ12
NOMESCO Finland
Flexible laryngoscopy
6.9
18.4
32
56
2108A
ICD-9 Finland
Benign neoplasm of lip, oral cavity and pharynx, Hypopharynx
+∞
18.0
17
*
C13.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of hypopharynx
188.4
16.8
17
*
D14.1
ICD-10 Finland
Benign neoplasm: Larynx
94.3
15.9
17
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
5.4
15.9
36
81
WX408
NOMESCO Finland
General anesthesy, balanced
3.6
13.9
70
284
R07.0
ICD-10 Finland
Pain in throat
6.1
12.2
23
43
UDQ22
NOMESCO Finland
Microlaryngoscopy
20.9
11.9
17
9
DQA10
NOMESCO Finland
Biopsy of larynx
70.1
11.8
13
*
D38.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Larynx
38.0
11.5
14
*
GBB00
NOMESCO Finland
Tracheostomy
22.0
11.4
16
8
ZXE00
NOMESCO Finland
One hour or less
3.1
11.3
91
475
R4190
NOMESCO Finland
Nutritional therapy
11.8
11.1
20
19
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
46.8
11.1
13
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
23.4
10.9
15
7
R13
ICD-10 Finland
Dysphagia
4.5
10.8
29
74
ENA10
NOMESCO Finland
Biopsy of pharynx
64.3
10.8
12
*
8070/3-C13.9
ICD-O-3
Squamous cell carcinoma, NOS, of hypopharynx, NOS
+∞
10.5
10
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
5.0
10.4
24
54
ZXD10
NOMESCO Finland
Scheduled procedure
2.9
10.3
84
435
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
58.6
9.8
11
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.2
9.6
21
45
C12
ICD-10 Finland
Malignant neoplasm of piriform sinus
+∞
9.5
9
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
5.5
9.3
19
38
K04.5
ICD-10 Finland
Chronic apical periodontitis
2.9
9.2
62
287
ZXC10
NOMESCO Finland
Use of laser
9.5
9.1
18
21
N02AA05
ATC
oxycodone; systemic
3.0
9.0
50
207
GD1AD
NOMESCO Finland
Thorax CT examination
4.9
8.6
20
45
WX402
NOMESCO Finland
General anaesthesia
2.9
8.0
48
207
A03FA01
ATC
metoclopramide; systemic, rectal
2.8
8.0
53
241
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.2
7.8
22
58
UDQ02
NOMESCO Finland
Direct laryngoscopy
19.5
7.7
11
6
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
26.4
7.7
10
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
83.7
7.5
8
*
UJC02
NOMESCO Finland
Rigid oesophagoscopy
16.7
7.3
11
7
A02BC05
ATC
esomeprazole; systemic
2.4
7.2
83
487
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
6.9
7.2
17
27
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.3
7.1
29
99
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
14.6
7.0
11
8
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.5
6.7
17
41
ZXA05
NOMESCO Finland
Left side
2.5
6.7
55
275
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.8
6.6
38
159
C01
ICD-10 Finland
Malignant neoplasm of base of tongue
72.6
6.5
7
*
C13.9
ICD-10 Finland
Malignant neoplasm: Hypopharynx, unspecified
72.6
6.5
7
*
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
72.6
6.5
7
*
A04AA01
ATC
ondansetron; systemic, rectal
3.5
6.5
24
77
Z2221
NOMESCO Finland
Medical doctor
2.4
6.4
57
295
R4110
NOMESCO Finland
Physiotherapy
2.4
6.3
59
312
C13.1
ICD-10 Finland
Malignant neoplasm: Aryepiglottic fold, hypopharyngeal aspect
+∞
6.3
6
*
ENB00
NOMESCO Finland
Excision or exploration of lesion of pharynx
+∞
6.3
6
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.6
6.1
44
205
EBA10
NOMESCO Finland
Operative extraction of tooth
3.2
6.1
26
91
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
106
657
2.73
8.68
10.7
6.9
1.20
1.21
mmol/l
0.92
95
570
54
242
2.84
8.39
2.9
2.7
1.07
0.91
e6/l
0.16
29
140
117
789
2.68
7.65
13.6
10.0
4.26
4.07
e9/l
0.42
107
691
95
588
2.46
7.35
9.7
6.0
1.19
1.21
mmol/l
1.80
90
549
86
509
2.45
7.35
4.4
3.1
—
—
—
0
0
50
230
2.69
7.27
3.1
2.9
2.06
1.79
e6/l
0.12
25
130
71
388
2.46
7.20
3.8
3.0
0.45
0.59
e6/l
0.18
58
298
23
71
3.60
6.57
1.9
1.8
—
—
—
0
0
92
582
2.32
6.51
7.3
4.6
33.55
35.53
g/l
2.53
83
551
75
443
2.28
6.16
5.0
3.6
2.33
2.35
mmol/l
0.55
66
396
43
210
2.42
5.37
2.1
1.9
—
—
—
0
0
56
307
2.25
5.37
2.9
2.3
—
—
—
0
0
96
655
2.12
5.22
17.2
13.7
1.47
1.28
inr
0.34
23
203
51
273
2.26
5.15
1.5
2.0
1.21
1.37
mg/l
0.25
46
216
125
959
2.28
4.85
5.2
3.8
14.71
14.83
pmol/l
0.20
116
853
89
611
2.00
4.53
3.1
2.6
—
—
—
0
0
80
536
1.96
4.31
2.0
1.9
86.72
93.28
pmol/l
0.54
41
293
12
25
5.09
4.28
1.4
1.3
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
14
37
4.04
4.00
2.3
2.4
0.25
0.39
u/ml
—
9
21
142
1192
2.43
3.79
6.2
4.5
1.98
1.97
mu/l
0.01
133
1067
131
1067
2.13
3.74
12.4
8.0
85.97
80.06
u/l
0.51
126
1004
31
154
2.25
3.66
2.1
1.8
—
—
—
0
0
106
808
1.88
3.62
8.0
4.6
7.12
6.69
mmol/l
0.93
101
761
7
9
8.06
3.59
1.3
1.3
—
—
—
0
0
30
150
2.22
3.48
2.0
1.8
—
—
—
0
0
24
109
2.41
3.46
3.1
2.4
63.00
63.57
ml/min/173m2
—
9
44
43
250
1.98
3.37
3.2
3.4
2.47
2.46
mmol/l
0.25
38
220
33
174
2.12
3.36
10.8
7.1
103.42
103.83
mmol/l
0.14
33
174
51
319
1.87
3.20
1.9
1.9
2.82
3.15
mg/l
0.61
42
281
151
1334
2.66
3.06
27.5
14.7
28.55
22.81
mg/l
1.39
133
1074
43
258
1.90
3.05
4.0
3.6
56.07
149.35
ng/l
1.07
36
202
19
82
2.49
3.04
1.6
1.3
—
—
—
0
0
58
383
1.80
3.04
3.2
2.8
7320.76
7534.27
umol/l
0.01
51
327
12
38
3.32
2.92
1.8
2.9
219.58
201.71
%
0.33
12
38
9
23
4.08
2.82
1.4
1.1
—
—
—
0
0
18
79
2.44
2.79
3.4
3.0
124.39
127.27
g/l
0.16
18
79
12
40
3.15
2.76
1.5
2.6
97.08
83.30
%
1.15
12
40
6
12
5.14
2.42
1.2
1.8
—
—
—
0
0
27
150
1.96
2.38
13.0
8.0
1.99
1.12
mmol/l
0.75
21
121
32
192
1.83
2.25
1.5
1.5
—
—
—
0
0
9
30
3.11
2.18
1.8
1.4
—
—
—
0
0
96
774
1.58
2.15
2.7
2.7
—
—
—
0
0
9
31
3.01
2.10
1.3
1.2
—
—
—
0
0
143
1287
1.87
1.94
24.7
14.1
80.28
79.45
ml/min/173m2
0.16
127
1056
106
887
1.55
1.91
4.0
3.4
74.21
52.09
u/l
1.08
97
840
5
12
4.26
1.83
1.0
1.1
—
—
—
0
0
58
431
1.53
1.79
6.6
3.8
26.42
12.49
mg/mmol
0.48
41
272
115
990
1.54
1.74
5.3
4.1
14.01
11.74
mm/h
0.71
108
911
5
14
3.65
1.62
1.2
1.4
—
—
—
0
0
66
519
1.45
1.51
3.6
2.6
180.61
141.12
ug/l
0.73
60
475
82
675
1.43
1.45
4.8
3.5
0.00
0.00
estimate
-0.00
15
126
81
667
1.42
1.42
6.7
4.8
0.00
0.00
estimate
-0.00
17
132
81
670
1.41
1.37
4.8
3.5
0.05
0.01
estimate
0.40
19
142
35
246
1.54
1.37
1.7
1.6
1014.46
1222.03
nmol/l
0.65
22
189
10
47
2.20
1.36
2.4
2.0
—
—
—
0
0
11
54
2.11
1.36
1.2
2.2
—
—
—
0
0
9
42
2.21
1.36
1.9
1.7
—
—
—
0
0
14
76
1.92
1.34
16.2
6.6
25.61
24.49
mmol/l
0.58
14
76
5
18
2.83
1.29
1.2
1.1
—
—
—
0
0
56
438
1.42
1.29
5.5
2.5
47.86
68.14
u/l
1.20
51
410
6
25
2.45
1.25
4.7
3.3
54.17
58.16
%
—
6
25
5
19
2.68
1.22
1.0
1.2
—
—
—
0
0
137
1265
1.50
1.12
7.9
6.0
43.28
40.21
mmol/mol
1.85
129
1177
12
66
1.88
1.12
3.9
2.6
0.78
0.64
%
0.61
12
66
7
31
2.31
1.12
1.1
1.3
—
—
—
0
0
151
1429
1.72
1.05
30.6
17.4
84.07
81.36
umol/l
0.26
151
1429
12
69
1.80
0.99
3.9
2.6
2.37
1.28
%
0.83
12
69
51
410
1.35
0.97
2.5
3.4
2214.26
1301.27
ng/l
0.50
43
342
6
27
2.27
0.94
1.3
1.4
—
—
—
0
0
14
86
1.69
0.94
1.5
1.5
—
—
—
0
0
8
42
1.95
0.90
1.9
2.7
—
—
—
0
0
6
30
2.04
0.88
1.0
1.1
—
—
—
0
0
64
542
1.30
0.84
4.3
3.9
31.46
52.61
ng/l
0.86
49
391
21
150
1.46
0.78
6.9
3.4
—
—
—
0
0
5
24
2.12
0.75
2.0
2.0
—
—
—
0
0
6
110
0.53
0.75
1.8
1.7
—
—
—
0
0
142
1348
1.40
0.72
5.3
5.2
2.68
2.74
mmol/l
0.30
133
1234
5
26
1.95
0.71
1.0
1.2
—
—
—
0
0
5
26
1.95
0.71
1.8
1.5
—
—
—
0
0
5
26
1.95
0.71
1.8
1.5
—
—
—
0
0
27
207
1.36
0.69
1.3
1.2
33.11
39.08
iu/ml
—
7
63
5
27
1.88
0.69
1.2
1.3
—
—
—
0
0
5
27
1.88
0.69
1.4
1.5
—
—
—
0
0
14
96
1.50
0.64
1.6
1.8
—
—
—
0
0
153
1478
1.52
0.62
38.2
21.5
38.50
40.65
%
2.71
147
1398
5
30
1.69
0.62
2.0
2.0
—
—
—
0
0
6
36
1.69
0.57
1.8
1.5
—
—
—
0
0
6
37
1.64
0.56
1.8
1.5
—
—
—
0
0
137
1314
1.26
0.46
4.6
4.7
1.33
1.44
mmol/l
2.46
128
1204
44
381
1.21
0.46
2.5
3.1
0.80
0.79
ug/l
0.03
33
250
20
158
1.30
0.44
3.6
4.8
14.30
86.06
ug/l
0.82
15
138
133
1274
1.23
0.44
4.2
4.2
1.33
1.29
mmol/l
0.31
121
1166
137
1318
1.24
0.42
4.6
4.7
4.48
4.61
mmol/l
0.69
128
1219
5
33
1.53
0.41
1.6
1.3
—
—
—
0
0
135
1299
1.22
0.40
5.4
4.7
6.32
6.04
mmol/l
1.03
129
1182
5
35
1.44
0.39
1.4
1.8
—
—
—
0
0
32
279
1.18
0.32
1.5
1.7
493.70
431.90
pmol/l
0.73
27
239
42
378
1.15
0.28
1.6
1.7
1.52
1.33
mmol/l
0.81
37
316
40
359
1.15
0.28
5.7
3.7
0.00
0.00
estimate
-0.00
14
127
5
37
1.36
0.24
1.6
1.3
—
2.52
—
0
10
5
39
1.29
0.23
2.4
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
2.9
—
13.77
—
0
10
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
162.01
—
0
14
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
7
62
1.13
0.17
1.1
1.0
—
—
—
0
0
19
171
1.13
0.13
9.3
7.5
—
—
—
0
0
13
148
0.87
0.13
1.5
1.5
—
—
—
0
0
5
46
1.09
0.09
3.6
1.7
—
—
—
0
0
10
88
1.15
0.08
1.8
1.7
—
—
—
0
0
17
157
1.09
0.07
4.1
4.9
28.08
31.66
%
1.20
12
99
54
525
1.04
0.06
5.7
3.7
—
—
—
0
0
66
647
1.03
0.04
4.2
5.1
1.93
2.83
ug/l
0.91
60
585
29
282
1.03
0.02
1.2
1.2
1.05
0.73
u/ml
—
6
80
53
523
1.02
0.01
4.1
4.6
26.06
21.26
%
0.96
26
258
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
10.25
—
0
5
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
59
1.02
-0.00
1.3
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
67.44
—
0
5
0
8
0.00
-0.00
0.0
4.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
9.72
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_HYPOPHARYNX and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_HYPOPHARYNX | 1.911 [1.25, 2.93] | 0.003 |
| Birth year | 0.988 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 51 out of 188 females with CD2_BENIGN_HYPOPHARYNX died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_HYPOPHARYNX | 2.396 [1.56, 3.67] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.073 |
During the follow-up period (1.1.1998 — 31.12.2019), 104 out of 275 males with CD2_BENIGN_HYPOPHARYNX died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_HYPOPHARYNX.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.142% | 0.394% |
| 5 | 0.951% | 2.999% |
| 10 | 2.338% | 8.24% |
| 15 | 4.195% | 14.837% |
| 20 | 6.865% | 24.105% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_HYPOPHARYNX – Benign neoplasm: Hypopharynx
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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