info icon

Intentional self-harm by hanging, strangulation and suffocation

VWXY20_INTENTI_SELF_H_HANGI_STRANGU_SUFFO

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 X70
  • Cause of death: ICD-10 X70

2 out of 7 registries used, show all original rules.

235

4. Check minimum number of events

None

235

5. Include endpoints

None

235

6. Filter based on genotype QC (FinnGen only)

235

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
X[6-7]|X8[0-4]

Similar endpoints

List of similar endpoints to Intentional self-harm by hanging, strangulation and suffocation based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

None

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 235 41 194
Unadjusted period prevalence (%) 0.07 0.01 0.09
Median age at first event (years) 51.76 37.94 54.69

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
201
Matched controls
2012
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
X70
ICD-10 Finland
Intentional self-harm by hanging, strangulation and suffocation
+∞
290.9
201
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
12.2
42.9
87
118
F10.0
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Acute intoxication
35.6
29.8
38
13
T36
ICD-10 Finland
Poisoning by systemic antibiotics
15.8
29.3
49
40
A98
ICPC
Health maint/preventive medicine
0.2
25.1
88
1600
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
17.7
24.1
38
26
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
9.0
19.2
42
57
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
5.9
13.8
40
81
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
11.2
12.9
24
24
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
24.6
11.8
16
7
N06AX11
ATC
mirtazapine; oral
3.2
11.7
80
348
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
6.0
11.7
33
64
N05BA04
ATC
oxazepam; oral
3.5
11.7
62
225
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
4.8
11.3
39
96
N05AH04
ATC
quetiapine; oral
3.5
10.4
55
197
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
5.1
10.4
33
74
F29
ICD-10 Finland
Unspecified nonorganic psychosis
7.4
10.3
24
36
N06AB03
ATC
fluoxetine; oral
4.5
9.9
36
93
N05AH03
ATC
olanzapine; systemic
5.0
9.0
29
66
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
11.5
9.0
16
15
N05AA02
ATC
levomepromazine; systemic
7.2
8.9
21
32
N06AX16
ATC
venlafaxine; oral
3.8
8.6
38
117
N06AB04
ATC
citalopram; systemic
3.0
8.3
53
214
F99
ICD-10 Finland
Mental disorder, not otherwise specified
12.5
7.7
13
11
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
7.6
7.7
17
24
Z91.5
ICD-10 Finland
Personal history of self-harm
+∞
7.3
7
*
N07BB01
ATC
disulfiram; oral
4.7
7.3
24
56
G93.1
ICD-10 Finland
Anoxic brain damage, not elsewhere classified
31.2
7.2
9
*
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
14.4
7.0
11
8
N02BE01
ATC
paracetamol; systemic, rectal
0.5
6.9
89
1278
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
9.2
6.7
13
15
Y19
ICD-10 Finland
Poisoning by and exposure to other and unspecified chemicals and noxious substances, undetermined intent
72.0
6.5
7
*
N05BA01
ATC
diazepam; systemic, rectal
3.1
6.4
35
126
N06AB06
ATC
sertraline; oral
3.6
6.3
28
87
I10
ICD-10 Finland
Essential (primary) hypertension
0.4
6.3
38
725
T71
ICD-10 Finland
Asphyxiation
+∞
6.3
6
*
AA400
NOMESCO Finland
Electroconvulsive therapy
13.1
6.1
10
8
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
13.1
6.1
10
8
F60.9
ICD-10 Finland
Personality disorder, unspecified
10.5
6.1
11
11

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: VWXY20_INTENTI_SELF_H_HANGI_STRANGU_SUFFO – Intentional self-harm by hanging, strangulation and suffocation

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).