Benign neoplasm: Connective and other soft tissue of abdomen

CD2_BENIGN_CONNSOFT_ABD

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D21.4&
  • Hospital discharge: ICD-9 2155
  • Cause of death: ICD-10 D21.4&
  • Cause of death: ICD-9 2155

2 out of 7 registries used, show all original rules.

102

4. Check minimum number of events

None

102

5. Include endpoints

None

102

6. Filter based on genotype QC (FinnGen only)

93

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D21
Name in latin
Neoplasma benignum textus connectivi abdominis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 814 549 263
Only index persons 728 504 224
Unadjusted period prevalence (%)
Whole population 0.01 0.02 0.01
Only index persons 0.02 0.02 0.01
Median age at first event (years)
Whole population 46.06 43.94 50.31
Only index persons 44.26 42.22 48.84

-FinnGen-

Key figures

All Female Male
Number of individuals 93 65 28
Unadjusted period prevalence (%) 0.02 0.02 0.01
Median age at first event (years) 47.67 42.85 58.86

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
102
Matched controls
1020
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D21.4
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of abdomen
3495.7
101.6
81
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
11.0
22.5
28
34
JAA10
NOMESCO Finland
Excision of lesion of abdominal wall
+∞
10.6
10
*
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
20.3
7.8
11
6
2155X
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Abdomen[ABDOMENIN BENIGNI PEHMYTKUDOSKASVAIN,TARK MÄÄRITTEL]
+∞
7.4
7
*
2155A
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Abdomen[ABDOMENIN BENIGNI PEHMYTKUDOSKASVAIN,SIDEKUDOSPERÄI]
+∞
6.3
6
*
6141
FHL
Exploration or removal of a local change in the abdominal wall (umbilical cord, tumor, hematoma, endometrioma)
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
32
146
2.74
4.87
3.9
3.0
91.72
73.64
ng/l
0.12
18
107
81
627
2.42
3.29
3.7
4.2
14.08
11.26
mm/h
0.85
73
574
41
248
2.09
3.14
2.9
4.0
7.39
7.40
ph
—
7
51
15
59
2.81
2.94
9.8
7.1
—
—
—
0
0
20
94
2.40
2.77
1.2
1.3
—
—
—
0
0
96
850
3.20
2.59
20.2
13.1
23.86
20.84
mg/l
0.37
84
663
42
276
1.89
2.43
3.2
2.0
—
—
—
0
0
32
197
1.91
2.23
6.3
3.9
—
—
—
0
0
21
111
2.12
2.21
3.2
1.7
—
—
—
0
0
53
392
1.73
1.98
8.2
6.7
1.21
1.22
mmol/l
0.50
45
332
13
59
2.38
1.93
1.5
1.6
—
—
—
0
0
73
600
1.76
1.78
4.1
4.3
—
—
—
0
0
36
247
1.71
1.71
3.4
3.0
31.73
291.84
e6/l
0.49
26
189
14
70
2.16
1.68
12.7
8.2
123.64
121.29
g/l
0.12
14
70
49
367
1.65
1.66
6.9
5.6
1.21
1.22
mmol/l
0.12
43
337
47
349
1.64
1.65
2.3
2.0
—
—
—
0
0
55
428
1.62
1.58
4.1
3.7
0.00
0.00
estimate
—
8
82
34
235
1.67
1.56
2.9
3.6
13.71
8.90
mg/mmol
0.15
25
151
96
884
2.46
1.54
23.6
15.4
74.42
73.84
umol/l
0.09
96
884
32
219
1.67
1.52
3.6
2.8
0.50
0.38
e6/l
0.18
23
159
54
423
1.59
1.48
6.0
4.9
0.00
0.00
estimate
—
8
85
17
97
1.90
1.46
18.0
6.5
104.06
103.69
mmol/l
0.12
17
97
29
196
1.67
1.43
3.4
3.3
—
—
—
0
0
45
341
1.57
1.40
3.9
3.3
5.50
5.75
ph
—
6
28
69
577
1.61
1.40
3.7
3.7
—
—
—
0
0
10
47
2.25
1.39
1.3
1.3
—
—
—
0
0
16
92
1.88
1.34
1.5
1.4
—
—
—
0
0
6
24
2.59
1.32
1.3
1.2
—
—
—
0
0
28
192
1.63
1.30
3.8
3.5
1.02
1.02
kg/l
—
5
26
61
501
1.54
1.30
9.0
9.0
4.28
4.21
e9/l
0.06
53
444
23
150
1.69
1.29
1.2
1.3
0.97
8.75
u/ml
—
6
63
31
219
1.60
1.28
3.5
2.8
—
—
—
0
0
6
25
2.48
1.26
1.0
1.3
—
—
—
0
0
39
293
1.54
1.23
4.1
3.5
185.29
59.04
e6/l
0.63
27
204
29
204
1.59
1.21
1.9
2.6
355.30
6234.18
umol/l
1.06
23
174
23
155
1.62
1.14
1.1
1.3
10.83
29.94
iu/ml
—
6
60
86
775
1.70
1.12
4.2
3.9
1.33
1.29
mmol/l
0.19
81
704
7
33
2.20
1.08
7.3
6.8
22.13
26.31
mmol/l
—
7
33
19
125
1.64
1.03
1.3
1.2
—
—
—
0
0
52
428
1.44
1.01
4.2
3.6
0.00
0.00
estimate
—
9
92
0
29
0.00
0.99
0.0
3.6
—
0.14
—
0
8
30
223
1.49
0.97
2.7
3.1
80.66
68.69
mg/l
0.06
22
147
16
103
1.66
0.94
1.4
1.3
—
—
—
0
0
85
774
1.59
0.93
6.1
5.4
40.28
39.42
mmol/mol
0.36
76
726
53
442
1.41
0.93
5.8
5.5
2.05
1.98
e9/l
0.07
47
399
53
443
1.41
0.92
6.1
5.7
0.18
0.18
e9/l
0.03
46
397
29
217
1.47
0.91
6.5
7.2
—
—
—
0
0
6
29
2.13
0.91
1.5
1.5
—
—
—
0
0
89
821
1.66
0.90
4.5
4.3
4.54
4.70
mmol/l
0.88
84
761
44
357
1.41
0.90
8.7
9.1
0.00
0.00
e9/l
0.50
36
286
90
834
1.67
0.87
5.0
4.8
2.63
2.77
mmol/l
0.89
85
768
51
428
1.38
0.84
6.0
5.4
0.63
0.59
e9/l
0.48
44
377
51
428
1.38
0.84
5.9
5.5
0.04
0.04
e9/l
0.07
44
377
9
53
1.76
0.78
1.6
1.5
1.25
1.27
g/l
—
9
47
30
233
1.41
0.77
3.7
3.8
0.00
0.00
estimate
—
7
82
87
806
1.54
0.77
4.5
4.5
5.86
5.87
mmol/l
0.02
80
744
93
878
1.67
0.76
17.4
12.6
—
—
—
0
0
7
38
1.90
0.75
2.7
2.5
0.61
0.72
%
—
7
38
7
38
1.90
0.75
20.7
7.8
—
—
—
0
0
5
25
2.05
0.74
1.4
1.2
18.30
10.87
u/l
—
5
19
17
119
1.51
0.73
1.3
1.5
176.00
394.07
titre
—
5
27
7
41
1.76
0.71
2.7
2.5
0.96
1.12
%
—
7
41
21
155
1.45
0.70
1.8
1.6
—
—
—
0
0
23
174
1.42
0.68
1.9
2.0
—
—
—
0
0
7
44
1.63
0.66
2.7
3.5
127.71
129.64
g/l
—
7
44
5
30
1.70
0.62
2.2
1.2
—
—
—
0
0
8
52
1.58
0.61
1.8
4.9
—
—
—
0
0
14
98
1.50
0.60
1.8
2.9
9.71
7.61
umol/l
0.20
14
81
19
247
0.72
0.60
1.7
1.5
—
—
—
0
0
97
931
1.85
0.59
30.1
19.9
38.69
39.94
%
0.80
91
880
9
59
1.58
0.57
3.6
2.1
5.07
5.00
ug/l
—
9
51
9
59
1.58
0.57
4.7
4.4
4.43
4.74
pmol/l
—
9
51
46
398
1.28
0.56
6.0
5.9
—
—
—
0
0
6
39
1.57
0.54
3.5
3.7
25.35
24.88
mmol/l
—
6
39
11
76
1.50
0.50
2.5
2.2
0.21
0.22
g/l
0.24
11
70
11
76
1.50
0.50
1.5
1.3
—
—
—
0
0
39
335
1.27
0.49
2.2
2.0
78.45
97.33
pmol/l
0.84
16
171
12
85
1.47
0.49
1.3
2.2
342.42
359.43
nmol/l
0.10
12
79
43
378
1.24
0.44
18.7
12.6
1.33
1.16
inr
0.41
13
115
8
58
1.41
0.43
1.0
1.2
—
—
—
0
0
29
245
1.26
0.41
3.3
2.9
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
9
69
1.33
0.38
4.4
3.1
—
—
—
0
0
9
70
1.31
0.38
2.7
4.0
—
—
—
0
0
32
279
1.21
0.34
2.8
2.5
63.89
54.07
u/l
0.76
27
257
33
289
1.21
0.34
3.9
3.7
2.36
2.36
mmol/l
0.04
33
253
24
206
1.22
0.30
1.5
1.2
0.74
0.81
u/ml
—
7
60
5
37
1.37
0.24
1.2
1.1
—
—
—
0
0
18
209
0.83
0.24
1.8
1.4
18.73
21.47
nmol/l
0.47
18
172
7
95
0.72
0.23
1.7
1.9
—
—
—
0
0
13
107
1.25
0.23
1.5
1.8
—
—
—
0
0
5
42
1.20
0.22
6.0
3.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
2.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
13
108
1.23
0.21
2.2
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
5.3
—
—
—
0
0
0
13
0.00
0.21
0.0
2.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
5
65
0.76
0.17
2.6
4.3
—
0.50
—
0
18
8
71
1.14
0.16
1.3
1.5
—
—
—
0
0
9
78
1.17
0.16
1.3
1.1
—
—
—
0
0
33
308
1.11
0.13
3.3
4.1
26.49
44.39
ng/l
0.46
20
206
5
45
1.12
0.10
2.8
1.6
—
—
—
0
0
5
47
1.07
0.09
1.6
3.2
—
7.46
—
0
5
6
58
1.04
0.08
2.8
1.9
61.18
67.32
g/l
—
6
52
7
67
1.05
0.08
2.0
2.3
—
—
—
0
0
22
234
0.92
0.07
3.7
3.9
—
—
—
0
0
30
288
1.06
0.05
3.8
2.8
—
—
—
0
0
25
247
1.02
0.00
4.7
3.3
—
—
—
0
0
18
181
0.99
0.00
1.6
1.3
2.55
2.51
g/l
0.02
11
101
9
99
0.90
0.00
1.1
1.5
—
—
—
0
0
7
74
0.94
0.00
2.0
4.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.8
—
0.66
—
0
6
9
92
0.98
-0.00
1.2
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
9.2
—
999.20
—
0
5
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
10.8
—
1610.40
—
0
5
0
5
0.00
-0.00
0.0
2.4
—
69.20
—
0
5
6
59
1.02
-0.00
1.7
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
1.68
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_CONNSOFT_ABD and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_CONNSOFT_ABD 1.671 [1.13, 2.47] 0.01
Birth year 0.997 [0.99, 1.01] 0.464

During the follow-up period (1.1.1998 — 31.12.2019), 55 out of 382 females with CD2_BENIGN_CONNSOFT_ABD died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_CONNSOFT_ABD.

N-year risk Females Males
1 0.156% No data
5 1.052% No data
10 2.632% No data
15 4.982% No data
20 8.626% No data

Relationships between endpoints

Index endpoint: CD2_BENIGN_CONNSOFT_ABD – Benign neoplasm: Connective and other soft tissue of abdomen

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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