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This is a non-core endpoint: only basic statistics are computed.

Carcinoma in situ of breast, other/unspecified

DOID EFO Endpoint Browser

CD2_INSITU_BREAST_NOS

breast ductal carcinoma in situ: A carcinoma entirely confined to the mammary ducts. It is also known as DCIS. There is no evidence of invasion of the basement membrane. Currently, it is classified into three categories: High-grade DCIS, intermediate-grade DCIS and low-grade DCIS. In this classification the DCIS grade is defined by a combination of nuclear grade, architectural growth pattern and presence of necrosis. The size of the lesion as well as the grade and the clearance margins play a major role in dictating the most appropriate therapy for DCIS.

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Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D05.7&, D05.9&
  • Hospital discharge: ICD-9 — 2330
  • Cause of death: ICD-10 — D05.7&, D05.9&
  • Cause of death: ICD-9 — 2330

2 out of 7 registries used, show all original rules.

492

4. Check minimum number of events

None

492

5. Include endpoints

None

492

6. Filter based on genotype QC (FinnGen only)

474

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 474 474 -
Unadjusted period prevalence (%) 0.17 0.17 -
Median age at first event (years) 58.67 58.67 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
492
Matched controls
4920
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
76.1
307.7
180
37
D05.9
ICD-10 Finland
Carcinoma in situ of breast, unspecified
+∞
307.7
351
*
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
75.2
307.7
263
74
PJA12
NOMESCO Finland
Sentinel node biopsy
9.6
138.3
234
425
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
10.4
126.6
175
247
HAB40
NOMESCO Finland
Wedge excision of mammary gland
9.9
126.6
188
290
HAC20
NOMESCO Finland
Total mastectomy
11.4
123.4
153
187
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
19.9
104.6
85
51
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
21.5
98.8
77
42
C50.99
ICD-10 Finland
Breast, unspecified
11.1
97.2
117
135
TQW20
NOMESCO Finland
Tatoe
23.5
95.1
71
35
D05.7
ICD-10 Finland
Other carcinoma in situ of breast
+∞
94.9
88
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
7.3
74.6
130
230
2330A
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Breast
+∞
70.5
66
*
HA1AA
NOMESCO Finland
X-ray mammography
5.7
68.8
171
423
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
5.7
63.0
146
337
HAC15
NOMESCO Finland
Subcutaneous mastectomy with excision of mamilla
24.1
60.3
44
20
C50
ICD-10 Finland
Malignant neoplasm of breast
8.8
57.7
79
105
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
5.2
50.3
127
311
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
11.3
50.2
55
54
115
Kela drug reimbursment
Breast cancer
4.5
49.8
164
496
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
6.4
47.7
89
165
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
6.0
41.2
81
157
8503/2-C50.9
ICD-O-3
Noninfiltrating intraductal papillary adenocarcinoma of breast, NOS
217.2
39.4
40
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
5.1
37.8
91
211
9703
FHL
Breast resection
11.7
36.0
38
35
ZZR10
NOMESCO Finland
Flap of skin and muscle
14.2
34.3
32
24
HAE99
NOMESCO Finland
Other reconstruction of breast
14.2
34.3
32
24
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
8.3
34.1
47
62
HAB00
NOMESCO Finland
Excision of lesion of mammary gland
6.2
33.7
62
112
D05.0
ICD-10 Finland
Lobular carcinoma in situ
79.6
33.3
37
5
HAB99
NOMESCO Finland
Other partial excision of mammary gland
6.6
32.3
55
92
N63
ICD-10 Finland
Unspecified lump in breast
4.2
30.2
93
260
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
5.5
28.8
59
118
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.8
25.1
174
797
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
5.2
25.0
54
113
Z31.5
ICD-10 Finland
Genetic counselling
4.7
24.7
62
147
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
6.7
24.4
40
64
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
6.7
24.4
40
64
L02BA01
ATC
tamoxifen; oral
4.1
24.3
74
204
WX702
NOMESCO Finland
Supraglottic ventilation device
4.3
23.9
68
178
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
4.1
23.4
70
190
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
8.8
23.4
30
36
WZC00
NOMESCO Finland
Treatment plan or consultation
2.5
22.4
233
1289
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
6.9
22.0
35
54
9707
FHL
Ablation of mammae and removal of axillary lymph nodes
24.5
21.5
30
13
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
9.4
21.4
26
29
N60.9
ICD-10 Finland
Benign mammary dysplasia, unspecified
20.6
21.1
31
16
L02BG04
ATC
letrozole; oral
3.2
20.6
97
355
ZX080
NOMESCO Finland
Image guided radiotherapy
5.8
20.1
38
70
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
4.8
18.1
42
93
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
5.8
17.7
33
60
D05
ICD-10 Finland
Carcinoma in situ of breast
186.4
17.6
18
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
6.4
17.0
29
48
Z80.3
ICD-10 Finland
Family history of malignant neoplasm of breast
5.5
17.0
34
66
XX3DW
NOMESCO Finland
Time consuming IT work
2.8
16.2
91
364
WX402
NOMESCO Finland
General anaesthesia
2.4
16.2
137
671
WF003
NOMESCO Finland
Adjuvant radiotherapy
4.5
14.8
37
87
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
4.0
14.7
44
119
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.2
14.3
39
98
H02AB02
ATC
dexamethasone; systemic
2.6
14.2
99
441
A04AA02
ATC
granisetron; systemic, transdermal
3.1
13.3
61
217
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
4.1
13.0
37
96
X76
ICPC
Malignant neoplasm breast female
4.3
13.0
34
83
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
4.2
12.7
35
89
HAD99
NOMESCO Finland
Other plastic operation on breast
11.4
12.6
23
21
9702
FHL
Breast exploration and possible tumor removal
5.0
12.3
27
57
D48.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Breast
4.7
12.0
28
62
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
3.8
11.8
37
103
HAD20
NOMESCO Finland
Liposuction of breast
66.6
11.7
13
*
ZZF00
NOMESCO Finland
Graft of adipose tissue
10.4
11.6
22
22
PJ5YQ, ,
NOMESCO Finland
122.8
11.5
12
*
ZZQ10
NOMESCO Finland
Free microvascular graft of skin and muscle
15.5
11.4
18
12
TQB05
NOMESCO Finland
Puncture of skin of trunk
10.0
11.4
22
23
9706
FHL
Ablation mammae, includes axillary exploration
35.9
11.3
14
*
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
4.4
11.0
28
67
5702
FHL
Local lymph node removal (eg armpit, groin)
15.9
10.9
17
11
1744A
ICD-9 Finland
Malignant neoplasm of female breast, Upper-outer quadrant
18.3
10.8
16
9
8500/2-C50.4
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of upper-outer quadrant of breast
61.4
10.7
12
*
QBA00
NOMESCO Finland
Puncture of skin of trunk
33.3
10.4
13
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
4.3
10.0
26
63
HA3ST
NOMESCO Finland
Removal of lesion of breast with radiological guidance
17.1
9.9
15
9
HAE05
NOMESCO Finland
Reconstruction of breast using soft tissue and prosthesis
9.8
9.8
19
20
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
13.7
9.7
16
12
HA4ST
NOMESCO Finland
Labeling mammary gland pathology with sterotactic guidance
13.7
9.7
16
12
X21
ICPC
Breast sympt/compl female other
4.2
9.6
26
65
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
30.7
9.4
12
*
HAD40
NOMESCO Finland
Mastopexy
11.0
9.3
17
16
HA1CG
NOMESCO Finland
Extensive MRI examination of mammary gland with high intensity magnet
4.3
9.3
24
58
C50.31
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, ductal tumor
4.8
8.9
20
43
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
3.6
8.8
29
84
A03FA01
ATC
metoclopramide; systemic, rectal
1.9
8.5
149
934
C50.9
ICD-10 Finland
Malignant neoplasm: Breast, unspecified
8.1
8.4
18
23
A04AD12
ATC
aprepitant; systemic
3.6
8.2
27
78
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
10.3
8.1
15
15
C50.19
ICD-10 Finland
Malignant tumor of the central part of the mammary gland, other or undeterminated histology
8.7
7.9
16
19
N64.9
ICD-10 Finland
Disorder of breast, unspecified
7.6
7.7
17
23
HAA10
NOMESCO Finland
Biopsy of mammary gland
6.9
7.7
18
27
8520/2-C50.9
ICD-O-3
Lobular carcinoma in situ, NOS, of breast, NOS
25.5
7.6
10
*
ZXE00
NOMESCO Finland
One hour or less
1.7
7.6
207
1466
HA1DG
NOMESCO Finland
Very extensive MRI examination of mammary gland with high intensity magnet
6.6
7.5
18
28
HA1AA, ,
SPAT
3.6
7.4
24
69
HWD00
NOMESCO Finland
Reoperation for deep haemorrhage in surgery of mammary gland
7.0
7.3
17
25
L02BG06
ATC
exemestane; oral
3.5
7.2
25
75
C50.39
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, other or undeterminated histology
12.3
7.1
12
10
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.2
7.0
58
276
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
3.0
7.0
30
103
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
7.0
139
898
D24
ICD-10 Finland
Benign neoplasm of breast
3.5
6.9
24
72
C50.10
ICD-10 Finland
Malignant tumor of the central part of the mammary gland, no histological veryfication
14.0
6.9
11
8
9719
FHL
Other measure in this category
40.6
6.8
8
*
JN4BD
NOMESCO Finland
Extensive body CT
2.1
6.7
63
315
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
3.8
6.7
20
54
1749X
ICD-9 Finland
Malignant neoplasm of female breast, Breast (female), unspecified
22.9
6.7
9
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
3.6
6.5
21
60
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
6.5
237
1789
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.5
6.4
41
174
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.0
6.4
27
92
XX1XN
NOMESCO Finland
Other isotope examination
5.6
6.4
17
31
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.4
6.2
43
189
C50.29
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland, other or undeterminated histology
6.4
6.2
15
24

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
141
427
4.23
42.05
1.4
1.4
—
—
—
0
0
89
189
5.53
41.06
1.4
1.3
—
—
—
0
0
129
539
2.89
21.70
1.4
1.2
—
—
—
0
0
35
72
5.16
16.40
1.0
1.1
—
—
—
0
0
265
1853
1.93
11.50
2.4
2.1
—
—
—
0
0
244
1665
1.92
11.35
3.5
3.4
2.37
2.37
mmol/l
0.44
228
1444
82
396
2.28
9.64
4.1
3.5
1.24
1.24
mmol/l
0.37
65
339
407
3416
2.11
9.03
8.8
7.2
73.69
79.14
u/l
3.31
377
3183
69
347
2.15
7.29
3.8
4.3
—
—
—
0
0
199
1425
1.67
6.81
4.3
3.6
7.40
7.40
ph
0.15
56
263
254
2018
1.53
5.16
2.2
2.4
—
—
—
0
0
285
2334
1.53
4.95
7.1
5.7
9.60
10.31
umol/l
0.89
267
2201
15
43
3.57
4.65
1.1
1.1
—
—
—
0
0
157
1163
1.51
4.23
6.5
6.8
—
—
—
0
0
178
1366
1.47
4.00
3.2
3.1
—
—
—
0
0
232
1874
1.45
3.99
10.4
9.4
0.00
0.00
e9/l
0.31
192
1539
292
2508
1.40
3.33
9.7
9.0
3.52
3.96
e9/l
4.11
269
2208
151
1906
0.70
3.26
2.0
2.0
99.29
98.36
pmol/l
0.07
71
879
349
3119
1.41
2.98
4.0
3.9
—
—
—
0
0
251
2127
1.37
2.97
4.9
5.0
1.22
1.22
mmol/l
0.03
218
1914
14
53
2.69
2.81
1.1
1.0
—
—
—
0
0
19
84
2.31
2.80
3.3
3.4
—
—
—
0
0
167
1338
1.38
2.76
2.0
2.2
—
—
—
0
0
18
371
0.47
2.69
2.2
3.6
—
—
—
0
0
15
329
0.44
2.65
2.1
2.3
3.81
4.27
kpa
0.92
15
320
20
393
0.49
2.62
2.3
2.8
6.15
5.89
kpa
0.87
20
383
92
671
1.46
2.58
2.4
2.8
0.83
0.81
mmol/l
1.07
84
617
120
928
1.39
2.43
2.7
2.8
2.46
2.47
mmol/l
0.31
114
819
21
387
0.52
2.28
2.3
2.8
2.31
2.42
mmol/l
0.08
21
323
393
3647
1.39
2.21
18.1
17.1
14.44
15.21
%
2.48
382
3580
263
2317
1.29
2.09
5.8
5.9
1.22
1.22
mmol/l
0.39
190
1969
71
957
0.70
2.09
3.6
4.7
1.01
1.02
kg/l
—
7
136
18
89
2.06
2.08
2.7
2.3
16.58
15.82
%
0.31
12
45
73
532
1.44
2.06
4.9
4.0
4.28
10.41
ug/l
1.87
62
437
16
78
2.09
1.93
2.3
3.2
4.33
4.41
e9/l
0.05
16
78
111
1376
0.75
1.92
3.4
3.6
10.10
5.97
mg/mmol
0.37
53
771
17
86
2.01
1.87
2.9
3.7
2.32
3.35
mmol/l
1.11
11
61
17
87
1.99
1.82
2.4
2.3
—
—
—
0
0
16
81
2.01
1.76
2.8
3.5
60.13
59.94
%
0.02
16
81
0
49
0.00
1.69
0.0
3.3
—
—
—
0
0
454
4369
1.51
1.65
14.5
13.4
—
—
—
0
0
22
355
0.60
1.54
3.9
4.9
1.13
1.39
mmol/l
1.25
22
346
0
42
0.00
1.53
0.0
1.1
—
—
—
0
0
11
217
0.50
1.52
2.5
2.6
26.01
25.58
mmol/l
0.21
11
211
108
1304
0.78
1.49
2.8
3.0
826.37
305.12
mg/l
0.29
52
736
8
170
0.46
1.49
3.1
3.2
—
—
—
0
0
112
1342
0.79
1.45
2.9
3.0
5.48
6.21
mmol/l
1.76
84
1122
51
374
1.41
1.43
2.1
3.6
21.51
66.31
u/ml
2.35
46
360
20
321
0.61
1.39
4.3
5.9
—
—
—
0
0
387
4052
0.79
1.32
5.1
5.9
39.10
39.76
mmol/mol
0.85
323
3710
6
134
0.44
1.29
2.3
2.0
897.17
180.94
ug/l
—
6
122
119
1003
1.25
1.27
1.4
1.3
—
—
—
0
0
21
131
1.63
1.25
2.1
2.8
—
—
—
0
0
9
167
0.53
1.21
4.4
4.3
—
—
—
0
0
22
142
1.58
1.16
1.4
1.3
37.35
35.50
iu/l
0.09
22
121
92
1096
0.80
1.12
1.5
1.5
19.44
22.12
nmol/l
1.09
72
907
13
73
1.80
1.12
2.6
2.5
—
—
—
0
0
58
454
1.31
1.11
2.8
2.2
5.68
7.28
umol/l
0.65
44
397
90
1073
0.80
1.10
2.1
2.2
2.59
3.21
mg/l
1.93
70
898
7
32
2.20
1.08
1.0
1.0
—
—
—
0
0
30
415
0.70
1.06
1.5
1.6
—
—
—
0
0
8
147
0.54
1.05
1.1
1.3
—
—
—
0
0
52
406
1.31
1.03
2.0
1.9
0.23
0.21
g/l
0.80
45
385
11
188
0.58
1.01
2.0
2.8
25.52
24.51
mmol/l
0.68
11
183
23
329
0.68
0.99
1.0
1.3
—
—
—
0
0
0
29
0.00
0.98
0.0
1.7
—
10.33
—
0
29
118
1023
1.20
0.96
2.0
2.2
—
—
—
0
0
27
369
0.72
0.91
1.1
1.4
—
—
—
0
0
164
1817
0.85
0.90
2.5
2.6
106.64
100.55
ug/l
0.22
139
1645
5
104
0.48
0.90
3.4
2.5
2.12
1.61
mmol/l
—
5
104
121
1374
0.84
0.89
2.0
2.0
135.72
144.31
u/l
0.13
110
1294
6
30
2.01
0.87
3.2
5.5
—
—
—
0
0
75
887
0.82
0.86
2.4
2.6
6.73
7.70
e6/l
0.13
64
811
126
1112
1.18
0.84
3.6
4.0
—
—
—
0
0
73
862
0.82
0.82
2.0
1.7
1207.51
1219.74
nmol/l
0.03
43
622
62
513
1.24
0.80
3.2
3.9
1.05
1.05
mmol/l
0.04
55
460
455
4449
1.30
0.80
15.6
16.2
139.85
139.79
mmol/l
0.21
433
4325
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
7
123
0.56
0.79
4.3
5.3
—
—
—
0
0
5
98
0.51
0.78
3.4
2.6
8.62
7.65
mmol/l
—
5
98
0
26
0.00
0.78
0.0
2.0
—
9.08
—
0
26
77
655
1.21
0.77
2.1
2.9
2.28
4.01
e6/l
1.34
40
328
220
2037
1.14
0.77
2.3
2.3
81.52
80.58
nmol/l
0.20
190
1794
9
55
1.65
0.74
1.8
2.0
88.09
90.12
%
—
9
55
72
840
0.83
0.72
3.4
3.8
273.31
218.03
ng/l
0.08
55
662
26
341
0.75
0.71
1.3
1.4
—
—
—
0
0
455
4459
1.27
0.69
15.8
16.3
3.94
3.94
mmol/l
0.21
430
4324
31
242
1.30
0.66
2.3
4.0
—
—
—
0
0
5
29
1.73
0.64
2.4
1.3
—
—
—
0
0
216
2021
1.12
0.61
15.7
13.3
1.23
1.20
inr
0.25
85
566
9
139
0.64
0.61
1.0
1.1
—
—
—
0
0
425
4343
0.84
0.61
5.1
5.3
2.92
2.81
mmol/l
1.49
345
3950
457
4489
1.25
0.61
17.9
16.8
69.30
70.53
umol/l
0.71
457
4489
0
20
0.00
0.60
0.0
1.6
—
527.90
—
0
20
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
8
52
1.55
0.59
3.6
1.8
33.38
31.04
pg
—
8
52
0
22
0.00
0.59
0.0
1.2
—
5.66
—
0
22
0
22
0.00
0.59
0.0
1.3
—
32.64
—
0
22
0
22
0.00
0.59
0.0
1.1
—
20.22
—
0
22
116
1046
1.14
0.59
3.0
3.4
93.63
94.18
%
0.07
111
1013
213
1995
1.12
0.59
5.2
6.0
—
—
—
0
0
20
264
0.75
0.59
2.2
2.4
—
—
—
0
0
0
23
0.00
0.58
0.0
1.6
—
—
—
0
0
44
524
0.82
0.57
1.9
2.0
77.90
121.27
ug/g
1.30
31
401
73
831
0.86
0.57
2.6
3.0
477.27
493.01
mosm/kgh2o
0.23
60
717
314
3011
1.12
0.56
4.0
4.8
—
—
—
0
0
40
479
0.82
0.55
3.9
3.9
—
—
—
0
0
208
1954
1.11
0.54
4.3
4.0
36.40
35.35
g/l
2.19
189
1813
13
181
0.71
0.53
1.8
2.1
1.49
1.61
g/l
—
8
159
9
62
1.46
0.53
4.9
2.2
—
—
—
0
0
6
39
1.54
0.53
5.2
2.5
—
—
—
0
0
6
96
0.62
0.52
6.8
3.7
81.50
2647.31
u/ml
—
6
91
52
445
1.19
0.52
1.5
1.6
—
—
—
0
0
6
40
1.51
0.51
1.3
1.4
—
46.73
u/l
—
0
13
26
207
1.27
0.50
1.5
2.0
—
—
—
0
0
74
831
0.87
0.49
1.3
1.3
23.16
13.11
u/ml
0.30
25
306
417
4254
0.87
0.49
4.6
4.9
5.84
5.90
mmol/l
0.39
327
3840
343
3318
1.11
0.48
3.9
4.3
13.64
13.49
mm/h
0.06
295
3031
7
47
1.50
0.47
1.0
1.1
—
—
—
0
0
468
4622
1.26
0.47
22.0
21.3
39.46
39.17
%
0.66
441
4289
5
82
0.61
0.46
1.4
1.1
—
—
—
0
0
468
4623
1.25
0.46
22.2
21.4
6.18
6.53
e9/l
4.25
448
4480
26
318
0.81
0.45
1.2
1.2
106.12
166.18
iu/ml
—
8
129
7
50
1.41
0.45
1.0
1.9
—
—
—
0
0
210
2212
0.91
0.45
4.6
5.8
0.17
0.18
e9/l
0.54
183
1932
468
4624
1.25
0.45
22.1
21.3
91.34
91.23
fl
0.20
452
4545
44
378
1.18
0.44
2.3
2.7
68.81
67.03
g/l
0.72
38
337
417
4248
0.88
0.44
4.4
4.7
4.93
4.86
mmol/l
0.76
340
3886
468
4625
1.24
0.44
22.1
21.3
255.30
260.55
e9/l
1.20
452
4498
468
4625
1.24
0.44
22.2
21.5
130.77
131.32
g/l
0.45
452
4546
468
4625
1.24
0.44
22.0
21.2
30.18
30.17
pg
0.03
452
4546
468
4625
1.24
0.44
22.1
21.4
4.36
4.37
e12/l
0.27
448
4486
396
4046
0.89
0.44
3.9
4.1
1.22
1.26
mmol/l
0.72
317
3635
458
4518
1.20
0.43
12.2
10.7
24.75
23.19
u/l
0.43
429
4334
97
1059
0.90
0.42
2.2
2.5
315.25
6642.91
umol/l
4.97
77
902
414
4217
0.88
0.42
4.5
4.6
1.64
1.61
mmol/l
0.83
337
3831
23
282
0.81
0.41
4.9
4.5
—
—
—
0
0
28
336
0.82
0.41
4.3
2.7
77.02
73.84
e9/l
0.16
22
253
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
1.6
—
28.12
—
0
8
0
16
0.00
0.41
0.0
23.4
—
1920.69
—
0
16
0
16
0.00
0.41
0.0
3.0
—
—
—
0
0
0
16
0.00
0.41
0.0
16.8
—
842.31
—
0
16
0
16
0.00
0.41
0.0
2.0
—
—
—
0
0
16
123
1.31
0.41
3.7
2.9
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
2.9
—
96410.45
—
0
11
0
17
0.00
0.40
0.0
1.4
—
133.47
—
0
17
0
17
0.00
0.40
0.0
3.1
—
31.33
—
0
12
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
282.62
—
0
13
23
187
1.24
0.39
3.4
2.6
241.78
983.40
u/ml
0.48
18
161
368
3589
1.10
0.39
4.6
4.4
15.12
14.93
pmol/l
0.71
305
3247
16
203
0.78
0.38
1.5
1.5
—
—
—
0
0
41
471
0.86
0.38
4.9
6.0
1.89
1.58
mmol/l
0.29
32
388
202
2119
0.92
0.38
4.5
5.5
0.56
0.56
e9/l
0.11
178
1833
207
2168
0.92
0.37
4.6
5.5
1.72
1.92
e9/l
1.93
181
1914
8
111
0.72
0.37
1.1
1.2
—
658.57
—
0
7
8
116
0.68
0.37
1.1
1.1
—
—
—
0
0
203
2124
0.92
0.35
4.5
5.5
0.04
0.04
e9/l
1.03
179
1832
20
244
0.81
0.35
1.2
1.4
—
—
—
0
0
59
656
0.89
0.35
2.3
2.2
12.06
12.51
umol/l
0.18
51
606
132
1237
1.09
0.35
1.6
1.6
1.30
1.34
mmol/l
0.35
82
1027
22
265
0.82
0.35
1.1
1.3
—
—
—
0
0
11
82
1.35
0.34
1.8
1.6
—
—
—
0
0
13
100
1.31
0.34
2.6
3.0
23.95
25.85
mmol/l
1.59
13
100
78
850
0.90
0.34
1.2
1.3
55.81
35.56
iu/ml
0.24
18
290
21
173
1.22
0.33
1.1
1.2
—
0.95
—
0
12
18
220
0.81
0.33
1.1
1.2
—
—
—
0
0
76
828
0.90
0.33
1.7
1.5
2.03
2.36
g/l
0.93
35
456
17
209
0.81
0.33
7.6
7.4
—
—
—
0
0
90
971
0.91
0.32
1.7
1.7
458.91
14249163.08
pmol/l
0.80
58
772
97
1042
0.91
0.32
2.8
4.1
—
—
—
0
0
7
53
1.33
0.31
1.3
1.0
—
—
—
0
0
41
363
1.14
0.30
1.7
1.5
—
—
—
0
0
7
55
1.28
0.30
2.0
1.2
—
—
—
0
0
7
55
1.28
0.30
2.0
1.2
—
—
—
0
0
7
55
1.28
0.30
2.0
1.2
—
—
—
0
0
7
55
1.28
0.30
2.0
1.2
—
—
—
0
0
140
1326
1.08
0.29
3.3
2.8
27.87
32.89
u/l
1.00
134
1265
30
344
0.86
0.29
1.1
1.1
—
—
—
0
0
16
194
0.82
0.28
1.0
1.1
—
134.00
—
0
5
243
2508
0.94
0.27
3.8
4.1
6.41
6.60
mmol/l
0.97
234
2345
8
66
1.22
0.27
1.1
1.3
—
—
—
0
0
46
415
1.12
0.27
2.2
2.2
29.43
35.66
u/l
0.99
37
340
28
320
0.87
0.26
2.6
3.3
—
—
—
0
0
30
263
1.15
0.26
1.2
1.2
108.32
134.57
u/ml
0.30
25
244
5
75
0.66
0.26
1.4
1.2
0.46
0.68
nmol/l
—
5
70
144
1506
0.94
0.24
3.1
3.8
54.93
112.62
e6/l
1.53
95
1047
18
211
0.85
0.23
1.4
2.5
0.18
0.19
e6/l
0.01
18
205
120
1142
1.07
0.23
2.7
3.1
—
—
—
0
0
15
125
1.21
0.22
5.1
8.3
—
—
—
0
0
52
564
0.91
0.22
2.2
2.2
21.97
21.16
%
0.12
42
475
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
5
43
1.16
0.21
1.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.9
—
—
—
0
0
57
529
1.09
0.21
1.2
1.2
—
—
—
0
0
220
2138
1.05
0.20
3.4
4.3
0.00
0.00
estimate
-0.00
54
412
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
2.2
—
2.97
—
0
6
6
49
1.23
0.20
1.2
6.1
7.72
7.51
mmol/l
—
6
40
6
50
1.20
0.19
2.0
1.5
4.33
81.23
u/ml
—
6
50
131
1364
0.95
0.19
1.8
2.2
54.01
57.19
u/l
0.30
111
1237
6
53
1.13
0.18
1.3
1.0
—
—
—
0
0
5
68
0.73
0.17
1.4
1.2
—
—
—
0
0
5
70
0.71
0.17
1.2
1.5
—
—
—
0
0
161
1660
0.96
0.16
2.9
3.4
—
—
—
0
0
8
72
1.11
0.16
1.1
1.3
—
—
—
0
0
21
233
0.90
0.14
2.8
3.2
7.43
7.41
ph
0.62
11
39
57
602
0.94
0.14
2.1
2.2
2.15
2.41
g/l
2.76
46
553
64
608
1.06
0.14
1.2
1.3
488.42
525.39
titre
0.07
19
141
409
4125
0.95
0.14
5.4
5.4
1.84
2.23
mu/l
0.71
346
3743
18
200
0.90
0.12
1.1
1.2
—
—
—
0
0
162
1658
0.97
0.11
3.5
3.5
28.40
50.19
ng/l
0.50
121
1175
14
157
0.89
0.11
1.1
1.2
—
—
—
0
0
36
338
1.07
0.11
2.9
3.7
1.00
0.71
%
0.30
15
98
36
338
1.07
0.11
3.3
4.0
0.00
1.09
%
0.50
13
81
118
1149
1.04
0.10
3.8
4.7
0.00
0.00
estimate
-0.00
49
381
95
979
0.96
0.10
1.2
1.3
0.59
1.57
u/ml
1.79
23
248
5
45
1.11
0.10
5.4
5.4
12.26
13.30
mg/l
—
5
39
5
45
1.11
0.10
1.0
1.0
—
—
—
0
0
5
47
1.06
0.09
1.0
1.2
30.40
32.41
g/l
—
5
42
220
2168
1.03
0.09
4.6
5.7
0.00
0.00
estimate
-0.00
48
374
6
55
1.09
0.09
1.0
1.1
—
—
—
0
0
6
55
1.09
0.09
1.0
1.1
—
—
—
0
0
15
136
1.11
0.08
1.1
1.3
—
2.23
—
0
17
6
57
1.05
0.08
2.5
2.6
—
—
—
0
0
6
57
1.05
0.08
2.3
2.8
—
—
—
0
0
265
2619
1.03
0.08
2.9
2.9
45.02
45.29
u/l
0.02
228
2398
5
63
0.79
0.08
1.6
2.0
—
—
—
0
0
8
76
1.05
0.07
1.1
1.2
—
—
—
0
0
68
699
0.97
0.06
1.4
1.2
—
—
—
0
0
62
602
1.03
0.06
1.8
1.9
—
—
—
0
0
54
523
1.04
0.06
1.3
1.3
—
—
—
0
0
423
4213
1.03
0.05
14.7
14.1
18.48
21.57
mg/l
1.45
333
3305
220
2179
1.02
0.05
3.5
4.3
0.00
0.02
estimate
0.80
48
379
195
1931
1.02
0.04
4.7
5.7
0.67
0.71
%
0.50
184
1766
118
1163
1.02
0.04
2.7
3.1
0.53
0.44
e6/l
0.12
82
874
101
995
1.02
0.04
1.4
1.6
1.49
1.04
mg/l
0.26
77
776
13
139
0.93
0.03
1.0
1.1
—
—
—
0
0
41
421
0.97
0.03
2.2
3.0
63.76
77.40
ng/l
0.80
29
369
10
108
0.92
0.03
1.7
1.8
—
—
—
0
0
201
2022
0.99
0.02
4.6
5.6
57.16
56.91
%
0.10
190
1863
206
2048
1.01
0.02
4.8
5.8
27.44
28.40
%
0.57
195
1891
26
252
1.03
0.02
1.2
1.3
—
—
—
0
0
202
2011
1.01
0.01
4.8
6.0
8.69
8.41
%
0.47
191
1850
33
323
1.02
0.01
1.3
1.3
—
—
—
0
0
35
343
1.02
0.01
2.3
2.4
—
—
—
0
0
38
373
1.02
0.01
3.2
3.9
1.50
1.02
%
0.36
16
118
39
397
0.98
0.01
1.2
1.4
—
—
—
0
0
127
1263
1.01
0.01
2.7
3.2
34.77
58.84
e6/l
0.52
88
958
13
124
1.05
0.00
1.5
2.4
—
—
—
0
0
18
174
1.04
0.00
1.6
1.8
—
—
—
0
0
172
1714
1.01
0.00
3.1
4.0
5.91
5.93
ph
0.03
11
94
27
275
0.98
0.00
2.1
2.9
4.52
4.46
pmol/l
0.08
19
238
11
107
1.03
0.00
7.2
4.1
—
—
—
0
0
16
163
0.98
0.00
1.4
1.5
—
—
—
0
0
36
356
1.01
0.00
3.3
4.0
0.21
0.12
%
0.33
14
101
10
102
0.98
0.00
1.2
1.2
—
—
—
0
0
40
398
1.01
0.00
1.7
1.9
373.91
374.21
nmol/l
0.00
35
365
107
1072
1.00
0.00
4.4
3.9
—
—
—
0
0
139
1388
1.00
0.00
3.7
3.6
—
—
—
0
0
132
1319
1.00
0.00
2.5
2.8
1018.99
1097.18
ng/l
0.15
107
1118
200
2003
1.00
0.00
4.7
5.7
2.62
2.82
%
0.67
186
1841
7
70
1.00
0.00
1.7
3.2
1.29
1.68
%
—
7
64
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
7
71
0.99
-0.00
1.4
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.4
1.5
271.00
274.54
mosm/kgh2o
—
5
35
0
6
0.00
-0.00
0.0
4.7
—
—
—
0
0
5
57
0.88
-0.00
1.6
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
17.62
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
5.70
—
0
6
0
9
0.00
-0.00
0.0
1.2
—
1.59
—
0
9
0
5
0.00
-0.00
0.0
1.6
—
29.80
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
68
0.88
-0.00
1.3
1.2
—
—
—
0
0
8
87
0.92
-0.00
2.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
3.51
—
0
9
0
8
0.00
-0.00
0.0
1.6
—
517.50
—
0
8
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_INSITU_BREAST_NOS – Carcinoma in situ of breast, other/unspecified

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).