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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart CD2_INSITU_BREAST_NOS_EXALLC for full statistics.

Carcinoma in situ of breast, other/unspecified

DOID EFO Endpoint Browser

CD2_INSITU_BREAST_NOS

breast ductal carcinoma in situ: A carcinoma entirely confined to the mammary ducts. It is also known as DCIS. There is no evidence of invasion of the basement membrane. Currently, it is classified into three categories: High-grade DCIS, intermediate-grade DCIS and low-grade DCIS. In this classification the DCIS grade is defined by a combination of nuclear grade, architectural growth pattern and presence of necrosis. The size of the lesion as well as the grade and the clearance margins play a major role in dictating the most appropriate therapy for DCIS.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D05.7&, D05.9&
  • Hospital discharge: ICD-9 — 2330
  • Cause of death: ICD-10 — D05.7&, D05.9&
  • Cause of death: ICD-9 — 2330

2 out of 7 registries used, show all original rules.

471

4. Check minimum number of events

None

471

5. Include endpoints

None

471

6. Filter based on genotype QC (FinnGen only)

471

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 471 471 -
Unadjusted period prevalence (%) 0.16 0.16 -
Median age at first event (years) 58.47 58.47 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
414
Matched controls
4139
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D05.9
ICD-10 Finland
Carcinoma in situ of breast, unspecified
+∞
323.0
301
*
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
82.7
202.0
222
57
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
92.6
141.8
153
26
PJA12
NOMESCO Finland
Sentinel node biopsy
10.8
83.2
185
288
D05.7
ICD-10 Finland
Other carcinoma in situ of breast
+∞
75.3
70
*
HAC20
NOMESCO Finland
Total mastectomy
13.8
75.3
140
148
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
11.7
75.2
154
199
HAB40
NOMESCO Finland
Wedge excision of mammary gland
10.8
70.1
150
207
2330A
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Breast
+∞
57.7
54
*
C50.99
ICD-10 Finland
Breast, unspecified
14.0
56.9
102
94
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
22.1
50.7
75
41
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
27.8
46.6
64
27
HA1AA
NOMESCO Finland
X-ray mammography
6.3
44.7
137
301
TQW20
NOMESCO Finland
Tatoe
35.7
43.6
56
18
115
Kela drug reimbursment
Breast cancer
5.7
41.1
138
335
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
6.2
39.4
119
252
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
7.8
38.3
95
152
8503/2-C50.9
ICD-O-3
Noninfiltrating intraductal papillary adenocarcinoma of breast, NOS
+∞
34.9
33
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
5.5
32.0
106
245
C50
ICD-10 Finland
Malignant neoplasm of breast
8.8
28.0
62
81
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
7.1
25.9
66
107
HAC15
NOMESCO Finland
Subcutaneous mastectomy with excision of mamilla
23.1
25.2
36
17
D05.0
ICD-10 Finland
Lobular carcinoma in situ
46.1
24.9
30
7
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.3
24.6
157
643
HAB00
NOMESCO Finland
Excision of lesion of mammary gland
8.1
24.2
56
78
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
5.7
23.7
72
147
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
5.8
21.8
65
129
ZZR10
NOMESCO Finland
Flap of skin and muscle
19.1
21.2
32
18
N60.9
ICD-10 Finland
Benign mammary dysplasia, unspecified
28.7
20.3
27
10
L02BA01
ATC
tamoxifen; oral
5.6
19.5
59
119
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
6.2
19.4
54
98
Z31.5
ICD-10 Finland
Genetic counselling
6.0
19.3
55
103
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
6.3
18.7
51
90
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
18.7
18.5
28
16
L02BG04
ATC
letrozole; oral
4.1
18.2
76
214
HAD99
NOMESCO Finland
Other plastic operation on breast
36.7
16.8
21
6
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
9.6
16.8
34
38
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
8.4
16.7
37
48
9703
FHL
Breast resection
11.1
16.5
31
30
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
8.7
15.9
34
42
9707
FHL
Ablation of mammae and removal of axillary lymph nodes
20.2
15.7
23
12
H02AB02
ATC
dexamethasone; systemic
3.4
15.7
85
295
N63
ICD-10 Finland
Unspecified lump in breast
3.9
15.3
66
191
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.4
15.1
177
983
HAB99
NOMESCO Finland
Other partial excision of mammary gland
5.5
14.8
44
87
WX702
NOMESCO Finland
Supraglottic ventilation device
4.6
14.7
53
129
HAE99
NOMESCO Finland
Other reconstruction of breast
13.2
14.6
25
20
D05
ICD-10 Finland
Carcinoma in situ of breast
155.2
14.6
15
*
XX3DW
NOMESCO Finland
Time consuming IT work
3.4
13.9
72
241
A04AA02
ATC
granisetron; systemic, transdermal
4.0
13.8
57
158
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
11.0
13.4
25
24
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
7.5
13.3
31
44
HAE05
NOMESCO Finland
Reconstruction of breast using soft tissue and prosthesis
23.4
13.0
18
8
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
5.4
13.0
39
78
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
5.2
12.6
39
81
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
8.4
12.5
27
34
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
7.1
12.5
30
45
ZX080
NOMESCO Finland
Image guided radiotherapy
6.7
12.4
31
49
Z80.3
ICD-10 Finland
Family history of malignant neoplasm of breast
8.6
12.2
26
32
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
5.7
11.6
33
62
9702
FHL
Breast exploration and possible tumor removal
7.0
10.9
26
39
ZZQ10
NOMESCO Finland
Free microvascular graft of skin and muscle
16.6
10.4
16
10
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
6.9
10.4
25
38
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
20.6
9.9
14
7
A03FA01
ATC
metoclopramide; systemic, rectal
2.2
9.8
123
676
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
5.1
9.7
30
63
TQB05
NOMESCO Finland
Puncture of skin of trunk
11.0
9.4
17
16
X76
ICPC
Malignant neoplasm breast female
5.0
9.0
28
59
5702
FHL
Local lymph node removal (eg armpit, groin)
12.9
8.9
15
12
HAA10
NOMESCO Finland
Biopsy of mammary gland
9.8
8.9
17
18
C50.19
ICD-10 Finland
Malignant tumor of the central part of the mammary gland, other or undeterminated histology
14.4
8.7
14
10
8500/2-C50.4
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of upper-outer quadrant of breast
51.1
8.7
10
*
ZZF00
NOMESCO Finland
Graft of adipose tissue
9.3
8.6
17
19
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
4.7
8.5
28
63
PJ5YQ
NOMESCO Finland
NA
+∞
8.4
8
*
HAD40
NOMESCO Finland
Mastopexy
11.1
8.4
15
14
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
14.9
8.2
13
9
HA1AE
SPAT
NA
7.1
8.2
19
28
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
5.6
7.9
22
41
9706
FHL
Ablation mammae, includes axillary exploration
13.4
7.9
13
10
HAC10
NOMESCO Finland
Subcutaneous mastectomy with preservation of mamilla
45.8
7.7
9
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
5.1
7.7
23
47
WF003
NOMESCO Finland
Adjuvant radiotherapy
3.8
7.6
31
86
HAD20
NOMESCO Finland
Liposuction of breast
81.5
7.4
8
*
A04AD12
ATC
aprepitant; systemic
4.8
7.3
23
50
HAD50
NOMESCO Finland
Removal of prosthetic implant from breast
20.4
7.2
10
5
HA1AA
SPAT
NA
5.6
7.0
19
35
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
14.1
6.9
11
8
HA4ST
NOMESCO Finland
Labeling mammary gland pathology with sterotactic guidance
14.1
6.9
11
8
HWD00
NOMESCO Finland
Reoperation for deep haemorrhage in surgery of mammary gland
9.5
6.8
13
14
C50.59
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, other or undeterminated histology
17.0
6.8
10
6
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
5.1
6.8
20
41
1749X
ICD-9 Finland
Malignant neoplasm of female breast, Breast (female), unspecified
22.9
6.7
9
*
C50.39
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, other or undeterminated histology
12.5
6.6
11
9
C50.89
ICD-10 Finland
Overall malignant tumor of the mammary gland, other or undeterminated histology
8.9
6.6
13
15
HA6BA
NOMESCO Finland
Breast tomosynthesis specimen
7.0
6.6
15
22
WX402
NOMESCO Finland
General anaesthesia
2.1
6.5
80
429
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
4.0
6.5
24
62
QB2S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in chest
11.3
6.3
11
10
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
4.5
6.3
21
49
HA1DG
NOMESCO Finland
Very extensive MRI examination of mammary gland with high intensity magnet
6.4
6.2
15
24
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.5
6.2
47
202
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
12.8
6.1
10
8
HA3ST
NOMESCO Finland
Removal of lesion of breast with radiological guidance
12.8
6.1
10
8
2393A
ICD-9 Finland
Neoplasm of unspecified nature, Breast
12.8
6.1
10
8
1744A
ICD-9 Finland
Malignant neoplasm of female breast, Upper-outer quadrant
6.9
6.1
14
21

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
133
409
4.14
38.72
1.4
1.4
—
—
—
0
0
80
181
5.12
34.17
1.4
1.3
—
—
—
0
0
121
518
2.80
19.33
1.4
1.2
—
—
—
0
0
35
69
5.40
17.21
1.0
1.1
—
—
—
0
0
234
1596
1.93
10.94
3.6
3.3
2.4
2.4
mmol/l
0.34
216
1368
251
1781
1.88
10.12
2.5
2.1
—
—
—
0
0
79
383
2.28
9.22
4.1
3.5
1.2
1.2
mmol/l
0.47
62
327
390
3275
2.11
8.66
9.1
7.1
73.8
79.2
u/l
3.15
362
3043
67
332
2.19
7.37
3.9
4.4
—
—
—
0
0
193
1381
1.67
6.68
4.4
3.6
7.4
7.4
ph
0.18
53
253
276
2250
1.55
5.03
7.2
5.6
9.5
10.3
umol/l
0.98
257
2118
239
1933
1.48
4.24
3.6
3.8
—
—
—
0
0
171
1298
1.50
4.13
3.2
3.1
—
—
—
0
0
14
42
3.40
4.07
1.1
1.1
—
—
—
0
0
149
1113
1.50
3.84
6.8
6.7
—
—
—
0
0
222
1794
1.45
3.82
10.6
9.4
0.0
0.0
e9/l
0.29
183
1469
143
1838
0.68
3.56
2.0
2.0
99.5
98.1
pmol/l
0.11
67
840
279
2405
1.39
3.07
10.0
9.0
3.5
3.9
e9/l
4.06
258
2115
19
81
2.40
3.02
3.3
3.4
—
—
—
0
0
241
2050
1.36
2.77
5.0
5.0
1.2
1.2
mmol/l
0.08
208
1830
14
316
0.43
2.67
2.2
2.3
3.6
4.2
kpa
1.58
14
307
19
376
0.48
2.55
2.4
2.7
6.2
5.9
kpa
0.96
19
366
88
641
1.46
2.50
2.4
2.8
0.8
0.8
mmol/l
1.03
80
586
18
360
0.48
2.49
2.2
3.6
—
—
—
0
0
363
3325
1.40
2.44
19.0
17.7
13.6
13.8
%
1.31
351
3252
157
1279
1.34
2.29
2.1
2.2
—
—
—
0
0
331
3001
1.35
2.27
4.0
3.9
—
—
—
0
0
383
3555
1.41
2.25
16.3
15.8
39.4
38.6
%
1.23
250
2375
71
509
1.46
2.19
5.0
3.9
4.3
10.6
ug/l
1.80
60
417
253
2229
1.29
2.03
5.9
5.9
1.2
1.2
mmol/l
0.35
183
1878
69
923
0.70
1.96
3.7
4.7
1.0
1.0
kg/l
—
7
129
10
39
2.60
1.93
1.2
1.2
0.1
2.1
u/ml
—
5
11
112
890
1.34
1.90
2.8
2.8
2.5
2.5
mmol/l
0.29
106
782
17
86
2.01
1.87
2.8
2.3
16.6
15.8
%
0.32
12
43
106
1316
0.75
1.86
3.9
3.8
10.4
6.0
mg/mmol
0.37
51
740
436
4181
1.58
1.84
14.7
13.4
—
—
—
0
0
11
47
2.37
1.79
1.0
1.0
—
—
—
0
0
20
341
0.57
1.71
3.5
5.0
1.2
1.3
mmol/l
0.64
20
328
161
1364
1.27
1.69
4.2
5.5
—
—
—
0
0
16
83
1.96
1.66
3.0
3.7
2.3
3.4
mmol/l
—
10
60
15
77
1.98
1.61
2.3
3.1
4.3
4.4
e9/l
0.09
15
77
16
85
1.91
1.57
2.5
2.3
—
—
—
0
0
0
42
0.00
1.53
0.0
3.3
—
—
—
0
0
18
304
0.58
1.51
4.0
6.0
—
—
—
0
0
103
1247
0.78
1.47
2.8
3.0
859.0
261.8
mg/l
0.32
50
700
15
80
1.90
1.46
2.9
3.4
59.5
60.0
%
0.04
15
80
107
1280
0.79
1.37
3.0
3.0
5.5
6.2
mmol/l
1.49
81
1063
49
360
1.40
1.37
2.1
3.6
22.0
68.3
u/ml
2.32
44
346
0
40
0.00
1.33
0.0
1.1
—
—
—
0
0
86
1052
0.78
1.32
1.5
1.5
19.4
22.2
nmol/l
1.08
68
870
371
3887
0.79
1.31
5.1
5.9
39.2
39.8
mmol/mol
0.71
310
3560
11
204
0.53
1.29
2.5
2.5
26.0
25.6
mmol/l
0.19
11
199
8
158
0.50
1.27
3.1
3.3
—
—
—
0
0
57
437
1.35
1.25
2.8
2.2
5.7
7.1
umol/l
0.56
43
381
13
70
1.88
1.25
2.6
2.5
—
—
—
0
0
11
198
0.54
1.18
4.0
2.0
1.0
1.1
%
0.40
11
198
21
134
1.59
1.16
1.4
1.3
38.8
36.7
iu/l
0.11
21
114
85
1024
0.79
1.15
2.2
2.2
2.6
3.2
mg/l
1.75
66
856
6
125
0.47
1.06
2.3
2.0
897.2
186.6
ug/l
—
6
113
21
310
0.66
1.05
1.0
1.3
—
—
—
0
0
68
829
0.79
1.02
2.0
1.7
1197.5
1229.8
nmol/l
0.09
41
602
7
132
0.52
1.00
1.1
1.3
—
—
—
0
0
9
161
0.55
0.99
4.4
4.3
—
—
—
0
0
155
1734
0.84
0.99
2.5
2.6
110.4
100.2
ug/l
0.40
131
1565
0
29
0.00
0.98
0.0
1.7
—
10.3
—
0
29
9
50
1.82
0.97
1.4
1.5
—
—
—
0
0
111
958
1.21
0.95
1.4
1.3
—
—
—
0
0
6
27
2.24
0.93
3.2
1.7
—
—
—
0
0
25
346
0.71
0.91
1.1
1.3
—
—
—
0
0
6
29
2.08
0.89
3.2
5.6
—
—
—
0
0
49
389
1.29
0.88
2.0
1.9
0.2
0.2
g/l
0.97
42
370
6
30
2.01
0.87
1.0
1.0
—
—
—
0
0
117
1325
0.84
0.85
2.0
2.0
138.0
145.7
u/l
0.11
106
1246
30
395
0.74
0.82
1.5
1.6
—
—
—
0
0
14
89
1.59
0.82
2.5
2.8
8.5
7.8
kpa
0.77
14
83
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
0
26
0.00
0.78
0.0
2.0
—
9.0
—
0
21
5
99
0.50
0.78
3.4
2.5
2.1
1.6
mmol/l
—
5
99
17
115
1.50
0.78
1.6
2.4
—
—
—
0
0
59
488
1.24
0.78
3.2
3.8
1.0
1.0
mmol/l
0.00
52
439
8
134
0.59
0.74
1.0
1.1
—
—
—
0
0
120
1068
1.17
0.73
3.7
4.1
—
—
—
0
0
5
27
1.86
0.68
2.4
1.3
—
—
—
0
0
5
93
0.53
0.67
3.4
2.6
8.6
7.6
mmol/l
—
5
93
61
516
1.21
0.66
22.5
22.7
1.4
1.2
inr
—
6
72
70
810
0.84
0.65
3.4
3.9
281.1
224.9
ng/l
0.08
53
640
435
4265
1.26
0.64
15.8
16.2
139.9
139.8
mmol/l
0.20
413
4146
98
869
1.16
0.63
4.1
4.4
—
—
—
0
0
44
362
1.24
0.63
2.3
2.8
68.8
67.0
g/l
0.72
38
326
0
21
0.00
0.60
0.0
1.7
—
—
—
0
0
8
52
1.55
0.59
3.6
1.8
33.4
31.0
pg
—
8
52
0
22
0.00
0.59
0.0
1.1
—
20.2
—
0
22
0
22
0.00
0.59
0.0
1.3
—
32.6
—
0
22
8
53
1.52
0.58
1.8
2.0
88.4
90.1
%
—
8
53
7
115
0.60
0.58
4.3
5.5
—
—
—
0
0
75
853
0.86
0.58
2.4
2.6
6.7
7.5
e6/l
0.11
64
764
12
172
0.69
0.57
1.9
2.1
1.6
1.6
g/l
—
7
152
29
230
1.28
0.57
2.4
4.0
—
—
—
0
0
6
38
1.59
0.54
5.3
2.6
—
—
—
0
0
435
4275
1.23
0.54
16.0
16.3
3.9
3.9
mmol/l
0.09
410
4145
329
3174
1.12
0.52
3.9
4.3
13.6
13.5
mm/h
0.06
284
2899
24
302
0.78
0.51
1.2
1.2
92.5
171.0
iu/ml
—
6
125
38
452
0.83
0.50
4.0
3.9
—
—
—
0
0
32
262
1.24
0.50
1.3
1.4
—
33.9
—
0
13
43
505
0.84
0.49
1.9
2.0
77.9
123.3
ug/g
1.35
31
384
26
322
0.80
0.49
1.3
1.4
—
—
—
0
0
399
4073
0.87
0.49
4.6
4.9
5.8
5.9
mmol/l
0.40
315
3674
7
45
1.56
0.49
1.0
1.8
—
—
—
0
0
91
1006
0.88
0.48
2.9
4.1
—
—
—
0
0
408
4157
0.86
0.48
5.2
5.3
2.9
2.8
mmol/l
1.36
332
3778
23
182
1.28
0.47
3.4
2.6
241.8
1000.8
u/ml
0.47
18
156
20
254
0.78
0.47
2.2
2.4
—
—
—
0
0
110
1006
1.12
0.46
3.1
3.4
94.9
94.1
%
0.09
105
974
7
49
1.43
0.46
1.3
1.0
—
—
—
0
0
21
165
1.29
0.45
1.1
1.3
—
1.0
—
0
12
49
424
1.17
0.45
1.5
1.6
—
—
—
0
0
16
121
1.33
0.44
3.8
2.9
—
—
—
0
0
436
4296
1.20
0.44
18.3
16.8
69.5
70.5
umol/l
0.53
436
4296
39
456
0.84
0.44
4.7
6.1
2.0
1.7
mmol/l
0.33
30
370
5
31
1.62
0.43
1.2
1.4
—
—
—
0
0
5
31
1.62
0.43
1.0
1.1
—
—
—
0
0
299
2886
1.10
0.43
4.1
4.8
—
—
—
0
0
16
206
0.77
0.42
1.1
1.2
—
—
—
0
0
198
1877
1.09
0.42
4.3
4.0
36.3
35.4
g/l
1.85
179
1736
0
15
0.00
0.41
0.0
2.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
3.2
—
—
—
0
0
0
16
0.00
0.41
0.0
3.2
—
31.3
—
0
11
0
16
0.00
0.41
0.0
23.4
—
1920.7
—
0
16
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
16.8
—
842.3
—
0
16
0
16
0.00
0.41
0.0
3.0
—
106036.0
—
0
10
16
205
0.77
0.41
7.8
7.6
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
133.5
—
0
17
0
17
0.00
0.40
0.0
1.6
—
768.4
—
0
5
197
2071
0.92
0.40
4.7
5.5
1.7
1.9
e9/l
1.66
171
1809
438
4322
1.19
0.40
12.5
10.7
24.8
23.2
u/l
0.41
410
4143
13
97
1.35
0.40
2.6
2.9
23.9
25.9
mmol/l
1.63
13
85
92
1003
0.90
0.39
2.2
2.5
316.2
7085.3
umol/l
4.97
72
843
128
1192
1.10
0.39
1.6
1.6
1.3
1.3
mmol/l
0.24
81
988
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
202
2118
0.92
0.38
4.7
5.8
0.2
0.2
e9/l
0.46
175
1847
5
36
1.39
0.38
1.2
1.3
—
50.5
u/l
—
0
12
352
3433
1.10
0.38
4.6
4.4
15.2
15.0
pmol/l
0.84
290
3100
193
2026
0.92
0.38
4.6
5.5
0.6
0.6
e9/l
0.00
169
1740
8
113
0.70
0.37
1.1
1.1
—
—
—
0
0
11
81
1.37
0.36
1.8
1.6
—
—
—
0
0
5
76
0.65
0.36
1.4
1.1
—
—
—
0
0
24
199
1.22
0.35
1.5
2.0
—
—
—
0
0
447
4424
1.20
0.34
22.5
21.2
91.4
91.2
fl
0.22
431
4348
23
275
0.83
0.34
4.9
4.5
—
—
—
0
0
72
788
0.90
0.34
1.3
1.3
23.2
12.4
u/ml
0.33
25
285
447
4425
1.20
0.33
22.6
21.3
4.4
4.4
e12/l
0.27
427
4290
447
4425
1.20
0.33
22.6
21.3
255.1
260.1
e9/l
1.09
431
4303
447
4425
1.20
0.33
22.4
21.2
30.2
30.2
pg
0.03
431
4349
447
4425
1.20
0.33
22.6
21.4
130.8
131.3
g/l
0.39
431
4349
447
4425
1.20
0.33
22.6
21.3
6.2
6.5
e9/l
3.95
427
4287
380
3869
0.91
0.33
3.9
4.1
1.2
1.3
mmol/l
0.61
304
3478
6
46
1.31
0.33
2.0
1.5
4.3
86.7
u/ml
—
6
46
6
46
1.31
0.33
1.0
1.1
—
—
—
0
0
26
305
0.84
0.32
2.8
3.3
—
—
—
0
0
195
2035
0.93
0.32
4.6
5.5
0.0
0.0
e9/l
0.97
170
1744
72
784
0.90
0.31
2.4
2.8
482.5
496.7
mosm/kgh2o
0.21
59
670
7
52
1.35
0.31
2.0
1.2
—
—
—
0
0
7
52
1.35
0.31
2.0
1.2
—
—
—
0
0
7
52
1.35
0.31
2.0
1.2
—
—
—
0
0
7
52
1.35
0.31
2.0
1.2
—
—
—
0
0
19
229
0.82
0.31
1.2
1.4
—
—
—
0
0
15
120
1.26
0.30
5.1
8.5
—
—
—
0
0
137
1446
0.93
0.30
3.2
3.8
49.1
103.6
e6/l
1.46
91
1005
16
195
0.81
0.29
1.1
1.2
—
—
—
0
0
8
109
0.73
0.29
1.1
1.2
—
658.6
—
0
7
8
63
1.27
0.28
1.1
1.3
—
—
—
0
0
401
4064
0.91
0.27
4.5
4.7
4.9
4.9
mmol/l
0.63
327
3716
232
2395
0.94
0.27
3.8
4.2
6.4
6.6
mmol/l
0.86
223
2239
8
67
1.20
0.26
1.1
1.3
—
—
—
0
0
5
73
0.68
0.26
1.4
1.2
0.5
0.7
nmol/l
—
5
68
398
4033
0.92
0.26
4.5
4.6
1.6
1.6
mmol/l
0.74
323
3663
28
318
0.87
0.25
4.3
2.8
77.0
73.7
e9/l
0.17
22
238
87
926
0.93
0.24
1.6
1.7
464.2
15027781.1
pmol/l
0.80
56
732
56
515
1.10
0.24
1.3
1.2
—
—
—
0
0
175
1685
1.06
0.23
10.9
8.3
1.2
1.2
inr
0.05
76
468
58
627
0.91
0.23
2.3
2.1
12.3
12.3
umol/l
0.02
49
569
74
791
0.92
0.23
1.7
1.6
2.0
2.3
g/l
0.85
35
433
5
39
1.29
0.23
1.0
1.4
—
—
—
0
0
5
41
1.22
0.22
5.4
4.9
12.3
13.3
mg/l
—
5
36
16
188
0.85
0.21
1.5
1.5
—
—
—
0
0
76
809
0.93
0.21
1.2
1.3
55.8
37.1
iu/ml
0.22
18
265
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
3.1
—
0
5
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
16
187
0.85
0.20
1.0
1.1
—
134.0
—
0
5
0
14
0.00
0.20
0.0
1.6
—
29.4
—
0
7
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
28
250
1.13
0.20
1.2
1.2
117.5
137.9
u/ml
0.21
23
234
6
49
1.23
0.20
1.2
6.1
7.7
7.5
mmol/l
—
6
40
6
49
1.23
0.20
1.3
1.0
—
—
—
0
0
152
1572
0.95
0.18
3.0
3.4
—
—
—
0
0
115
1104
1.06
0.17
3.8
4.7
0.0
0.0
estimate
0.00
48
364
5
67
0.74
0.17
1.2
1.5
—
—
—
0
0
5
67
0.74
0.17
1.4
1.2
—
—
—
0
0
390
3940
0.94
0.17
5.4
5.4
1.8
2.2
mu/l
0.68
328
3572
30
329
0.91
0.16
1.1
1.1
—
—
—
0
0
61
575
1.07
0.16
1.2
1.3
506.7
521.2
titre
0.03
18
135
15
130
1.16
0.16
1.1
1.3
—
2.2
—
0
15
35
323
1.09
0.15
2.9
3.8
1.3
0.5
%
—
10
62
35
323
1.09
0.15
3.3
4.1
0.0
1.3
%
—
10
67
29
315
0.92
0.14
1.2
1.3
—
—
—
0
0
406
4027
1.06
0.14
14.9
14.1
18.6
21.5
mg/l
1.28
318
3157
63
661
0.95
0.13
1.3
1.2
—
—
—
0
0
114
1104
1.04
0.12
2.7
3.1
—
—
—
0
0
14
158
0.88
0.12
1.5
1.5
—
—
—
0
0
51
537
0.94
0.12
2.1
2.2
22.3
20.9
%
0.21
41
448
22
240
0.91
0.11
1.1
1.3
—
—
—
0
0
26
240
1.09
0.11
1.2
1.3
—
—
—
0
0
18
197
0.91
0.10
1.4
2.5
0.2
0.2
e6/l
0.12
18
191
5
44
1.14
0.10
1.0
1.0
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
128
1311
0.97
0.10
1.8
2.2
50.4
57.4
u/l
2.00
107
1188
35
330
1.07
0.10
2.3
2.4
—
—
—
0
0
5
46
1.09
0.09
1.0
1.2
30.4
32.1
g/l
—
5
41
60
577
1.05
0.09
1.9
1.9
—
—
—
0
0
188
1849
1.03
0.09
4.7
5.7
0.7
0.7
%
0.51
178
1687
5
60
0.83
0.08
1.6
2.1
4.0
4.0
mmol/l
—
5
60
5
60
0.83
0.08
1.6
2.1
103.8
106.1
mmol/l
—
5
60
208
2051
1.03
0.08
3.5
4.2
0.0
0.0
estimate
0.00
48
367
12
133
0.90
0.07
1.0
1.1
—
—
—
0
0
36
343
1.05
0.07
1.8
1.5
—
—
—
0
0
195
1924
1.02
0.07
4.9
5.9
8.8
8.4
%
0.57
184
1766
198
1958
1.02
0.05
4.8
5.8
27.6
28.5
%
0.47
187
1785
96
942
1.02
0.05
1.5
1.6
1.5
1.1
mg/l
0.26
74
735
37
357
1.04
0.05
3.2
3.9
1.5
0.9
%
0.37
13
88
157
1587
0.98
0.04
3.5
3.6
29.1
50.9
ng/l
0.47
117
1126
208
2096
0.99
0.03
3.6
4.3
0.0
0.0
estimate
0.80
47
362
56
572
0.98
0.03
2.1
2.2
2.2
2.4
g/l
2.77
45
524
35
340
1.03
0.03
3.4
4.0
0.2
0.1
%
0.35
13
81
11
102
1.08
0.03
7.2
4.3
—
—
—
0
0
127
1283
0.99
0.03
2.5
2.8
1015.8
1110.4
ng/l
0.18
104
1084
21
219
0.96
0.03
2.8
3.3
7.4
7.4
ph
0.60
11
37
51
500
1.02
0.02
1.3
1.3
—
—
—
0
0
133
1318
1.01
0.02
3.7
3.6
—
—
—
0
0
14
148
0.94
0.02
1.1
1.2
—
—
—
0
0
36
369
0.97
0.02
1.2
1.4
—
—
—
0
0
101
1019
0.99
0.01
4.4
3.9
—
—
—
0
0
93
938
0.99
0.01
1.2
1.3
0.6
1.6
u/ml
1.76
22
238
122
1212
1.01
0.01
2.7
3.2
20.1
59.4
e6/l
1.46
85
919
37
377
0.98
0.01
1.8
1.9
370.7
374.4
nmol/l
0.04
32
347
113
1124
1.01
0.00
2.7
3.1
0.5
0.4
e6/l
0.16
79
841
10
104
0.96
0.00
1.7
1.8
—
—
—
0
0
17
167
1.02
0.00
1.6
1.9
—
—
—
0
0
26
263
0.99
0.00
2.1
2.9
4.6
4.5
pmol/l
0.19
18
226
41
407
1.01
0.00
2.2
2.9
63.8
76.4
ng/l
0.72
29
357
12
121
0.99
0.00
1.6
2.4
—
—
—
0
0
193
1932
1.00
0.00
4.7
5.5
56.9
56.8
%
0.04
182
1772
192
1916
1.00
0.00
4.7
5.6
2.7
2.8
%
0.51
178
1749
208
2085
1.00
0.00
4.7
5.8
0.0
0.0
estimate
0.00
47
358
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
136.7
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
9
99
0.91
0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
17.6
—
0
5
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
5
49
1.02
0.00
2.2
2.7
—
—
—
0
0
5
49
1.02
0.00
1.4
1.5
271.0
274.5
mosm/kgh2o
—
5
35
5
52
0.96
0.00
2.0
2.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
29.8
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
0.00
1.1
1.2
—
—
—
0
0
8
82
0.98
0.00
2.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
67
0.89
0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
3.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
1.6
—
0
9
0
6
0.00
0.00
0.0
7.0
—
—
—
0
0
5
59
0.85
0.00
1.6
2.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
5.7
—
0
6
0
9
0.00
0.00
0.0
1.6
—
3.5
—
0
9
5
52
0.96
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_INSITU_BREAST_NOS – Carcinoma in situ of breast, other/unspecified

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).