This is a non-core endpoint: only basic statistics are computed.
Hypersecretion of calcitonin
E4_HYPERSECCAL
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
8 |
4. Check minimum number of eventsNone |
8 |
5. Include endpointsNone |
8 |
6. Filter based on genotype QC (FinnGen only) |
8 |
Control definitions (FinnGen only)
- Control exclude
- E4_THYROID
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E07
- Name in latin
- Hypersecretio calcitonini
Similar endpoints
↥List of similar endpoints to
Hypersecretion of calcitonin
based on the number of shared cases.
Similar with more cases:
- Other disorders of thyroid
- Disorders of thyroid, IBD co-morbidities
- Disorders of the thyroid gland
- Used for control exclusion in common control thyroid runs
- Endocrine, nutritional and metabolic diseases
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 57 | 41 | 16 |
| Only index persons | 43 | 34 | 9 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | - | 55.55 | 54.65 |
| Only index persons | 46.51 | 47.77 | 41.75 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 8 | 7 | - |
| Unadjusted period prevalence (%) | 0.00 | 0.00 | - |
| Median age at first event (years) | 50.66 | 51.54 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3011397) Hemoglobin [Presence] in Urine by Test strip
0
20
0.00
0.72
0.0
4.1
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
0
12
0.00
0.23
0.0
1.4
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3014576) Chloride [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
14.6
—
102.5
—
0
8
(40768793) Breast Pathology biopsy report
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3021447) Carbon dioxide [Partial pressure] in Venous blood
0
8
0.00
0.00
0.0
2.9
—
6.0
—
0
8
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
2.0
—
3.6
—
0
5
(40761535) Cells panel - Urine sediment
0
8
0.00
0.00
0.0
3.9
—
—
—
0
0
(4010399)
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3000991) Gas panel - Venous blood
0
6
0.00
0.00
0.0
13.3
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3024354) Oxygen [Partial pressure] in Venous blood
0
5
0.00
0.00
0.0
3.4
—
3.8
—
0
5
(3021387) Prolactin [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
225.4
—
0
5
(3024891) Influenza virus A+B Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012544) pH of Venous blood
0
8
0.00
0.00
0.0
2.9
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
0
7
0.00
0.00
0.0
2.4
—
1.2
—
0
7
(3027944) Amphetamines [Presence] in Urine
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(4035726)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3002256) Pathology report gross observation
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_HYPERSECCAL and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have E4_HYPERSECCAL.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: E4_HYPERSECCAL – Hypersecretion of calcitonin
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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