ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2342 |
4. Check minimum number of eventsNone |
2342 |
5. Include endpointsNone |
2342 |
6. Filter based on genotype QC (FinnGen only) |
2342 |
Control definitions (FinnGen only)
- Control exclude
- K11_ENERCOLNONINF
Extra metadata
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- K51
- Name in latin
- Alia colitis ulcerosa specificata
Similar endpoints
↥List of similar endpoints to
Other ulcerative colitis
based on the number of shared cases.
Similar with more cases:
- Ulcerative colitis
- Inflammatory bowel disease
- Noninfective enteritis and colitis
- Autoimmune diseases related-to ILD
- Autoimmune diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12782 | 6042 | 6700 |
| Only index persons | 12237 | 5850 | 6387 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.18 | 0.17 | 0.19 |
| Only index persons | 0.23 | 0.22 | 0.24 |
| Median age at first event (years) | |||
| Whole population | 43.13 | 41.97 | 44.08 |
| Only index persons | 42.48 | 41.50 | 43.39 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2342 | 1229 | 1113 |
| Unadjusted period prevalence (%) | 0.45 | 0.42 | 0.49 |
| Median age at first event (years) | 43.94 | 41.20 | 46.96 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2114
- Matched controls
- 21138
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K50.1
ICD-10 Finland
Crohn disease of large intestine
+∞
323.0
355
*
K51.8
ICD-10 Finland
Other ulcerative colitis
4503599627370496.0
323.0
2113
*
H02AB06
ATC
prednisolone; systemic
9.3
323.0
1689
6321
A07EC02
ATC
mesalazine; oral, rectal
1849.9
323.0
1842
77
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
+∞
323.0
460
*
A07EA06
ATC
budesonide; oral, local oral
251.3
323.0
738
45
L04AX01
ATC
azathioprine; systemic
95.9
323.0
1027
206
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
6363.0
323.0
1329
6
K50.8
ICD-10 Finland
Other Crohn disease
+∞
323.0
402
*
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
2403.9
323.0
373
*
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
+∞
323.0
707
*
K50.9
ICD-10 Finland
Crohn disease, unspecified
1249.5
323.0
319
*
UJF30
NOMESCO Finland
Ileoscopy through colon
21.3
323.0
858
656
UJF32
NOMESCO Finland
Coloscopy
31.3
323.0
1682
2335
A07EA02
ATC
hydrocortisone; rectal
365.4
323.0
769
33
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
14.7
323.0
622
581
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
+∞
323.0
396
*
K51.5
ICD-10 Finland
Left sided colitis
8596.3
323.0
1230
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
323.0
1891
*
A07EC01
ATC
sulfasalazine; oral, rectal
12.1
306.6
609
686
K51
ICD-10 Finland
Ulcerative colitis
1696.5
305.7
290
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
53.6
292.4
350
78
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
738.0
269.2
260
*
H02AB07
ATC
prednisone; oral
7.1
244.5
691
1348
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
5.2
243.4
1001
3105
L01BB02
ATC
mercaptopurine; oral
231.7
242.3
246
12
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
+∞
240.3
226
*
K50.0
ICD-10 Finland
Crohn disease of small intestine
2104.5
212.0
202
*
J01MA02
ATC
ciprofloxacin; systemic
4.2
201.7
1161
4771
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
125.8
201.5
215
19
D94
ICPC
Chronic enteritis/ulcerative colitis
286.1
181.8
183
7
A07EA01
ATC
prednisolone; rectal
464.7
174.5
172
*
P01AB01
ATC
metronidazole; oral, rectal
3.7
168.5
1164
5300
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
+∞
166.9
158
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.0
159.9
848
3057
ZX120
NOMESCO Finland
Intravenous
6.5
154.9
445
829
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
+∞
141.2
134
*
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
130.6
124
*
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
+∞
128.5
122
*
K83.0
ICD-10 Finland
Cholangitis
32.1
126.7
169
57
TPH04
NOMESCO Finland
Cathetrisation of vein
3.8
125.1
656
2248
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
+∞
124.2
118
*
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
71.8
123.4
141
21
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
+∞
119.9
114
*
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
+∞
99.8
95
*
A05AA02
ATC
ursodeoxycholic acid; oral
16.3
98.6
163
108
L04AB04
ATC
adalimumab; parenteral
13.9
91.1
161
125
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
53.6
89.5
107
21
UJF92
NOMESCO Finland
Capsular endoscopy
14.0
86.6
152
116
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.2
86.3
533
1988
A06AC01
ATC
ispaghula (psylla seeds); oral
3.0
82.1
582
2378
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
10.6
78.7
158
160
A07DA03
ATC
loperamide; oral
8.6
76.6
174
219
WX302
NOMESCO Finland
Thoracal epidural anesthesy
6.2
73.1
208
364
A07EC03
ATC
olsalazine; oral
711.2
70.5
69
*
Z93.2
ICD-10 Finland
Ileostomy status
129.5
70.4
75
6
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
16.4
70.2
115
74
JFH10
NOMESCO Finland
Total colectomy and ileostomy
151.1
69.4
73
5
4AA12
NOMESCO Finland
NA
149.0
68.4
72
5
4AB02
NOMESCO Finland
NA
124.2
67.3
72
6
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
67.1
929
5390
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
46.7
66.3
81
18
C10AC01
ATC
colestyramine; oral
10.8
66.1
131
129
A02BC02
ATC
pantoprazole; systemic
2.2
60.8
1365
9677
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
604.7
60.0
59
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.7
58.2
283
855
H02AB09
ATC
hydrocortisone; systemic
9.0
56.4
123
144
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.3
56.4
320
1090
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.7
56.2
170
319
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.7
55.4
202
467
WX002
NOMESCO Finland
Sedation and analgesia
2.6
54.8
470
2086
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.3
53.1
305
1042
L04AD01
ATC
ciclosporin; systemic
9.2
52.6
113
129
K50
ICD-10 Finland
Crohn disease [regional enteritis]
266.9
51.3
52
*
JFF10
NOMESCO Finland
Loop enterostomy
29.2
50.3
68
24
K92.1
ICD-10 Finland
Melaena
5.4
50.0
157
308
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
3.4
49.2
267
874
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
+∞
48.1
46
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
7.3
46.4
115
165
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
10.0
46.0
94
98
L04AC05
ATC
ustekinumab; parenteral
85.4
45.0
50
6
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
+∞
43.9
42
*
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
10.4
43.6
87
87
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
43.0
793
4923
JFH11
NOMESCO Finland
Laparoscopic colectomy
+∞
42.8
41
*
UJG02
NOMESCO Finland
Proctoscopy
8.7
42.2
93
111
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
41.8
40
*
1370
FHL
Colonoscopy, whole colon
40.2
40.7
51
13
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
11.1
38.5
74
69
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
46.9
37.9
46
10
4AA33
NOMESCO Finland
NA
+∞
37.6
36
*
L04AA01
ATC
[U] ciclosporin; systemic
9.6
37.6
78
84
JF1BD
NOMESCO Finland
Very extensive small bowel CT
25.3
37.2
52
21
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.2
36.3
144
360
JAH00
NOMESCO Finland
Laparotomy
6.6
35.8
94
147
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
32.0
35.8
47
15
UJK02
NOMESCO Finland
ERCP
7.0
35.7
90
133
N02AX02
ATC
tramadol; systemic, rectal
1.8
35.5
837
5572
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
35.3
476
2568
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.8
35.2
91
139
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
6.2
35.2
97
162
A07AA09
ATC
vancomycin; oral
13.3
34.7
61
47
3042
Kela drug reimbursment
NA
+∞
34.5
33
*
253
Kela drug reimbursment
NA
+∞
34.5
33
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.4
34.4
317
1430
K56.7
ICD-10 Finland
Ileus, unspecified
10.0
34.1
69
71
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
7.5
34.1
82
113
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
4.7
33.9
120
268
6419
FHL
Other measure in this category
177.8
33.8
35
*
L04AB06
ATC
golimumab; parenteral
11.6
33.6
63
56
K51.4
ICD-10 Finland
Inflammatory polyps
+∞
33.4
32
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.2
33.2
184
607
A02BC01
ATC
omeprazole; systemic
2.0
32.7
544
3177
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.7
32.3
147
415
Z93
ICD-10 Finland
Artificial opening status
62.7
32.1
37
6
JFF13
NOMESCO Finland
Terminal enterostomy
53.7
31.3
37
7
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
+∞
31.3
30
*
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
+∞
31.3
30
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
30.3
246
1033
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
18.8
30.1
46
25
UJK12
NOMESCO Finland
Peroral cholangioscopy
69.0
29.9
34
5
A02BC03
ATC
lansoprazole; oral
1.9
29.9
568
3463
JHA00
NOMESCO Finland
Anal or perianal incision
7.7
29.9
70
93
K59.1
ICD-10 Finland
Functional diarrhoea
3.9
29.6
127
341
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
4.4
29.3
110
261
C05AA08
ATC
fluocortolone; rectal, topical
2.3
29.3
308
1475
B01AB05
ATC
enoxaparin; parenteral
1.9
28.5
560
3446
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
36.6
28.4
36
10
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
+∞
28.2
27
*
N02BE01
ATC
paracetamol; systemic, rectal
1.8
28.2
1722
14876
R50.9
ICD-10 Finland
Fever, unspecified
2.2
28.0
317
1567
JN3AD
NOMESCO Finland
Abdominal CT examination
2.9
27.5
182
676
3AC01
NOMESCO Finland
NA
8.8
27.3
59
69
K62.8
ICD-10 Finland
Other specified diseases of anus and rectum
11.3
27.1
51
46
JFB00
NOMESCO Finland
Partial resection of small intestine
8.5
26.8
59
71
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.1
26.7
86
174
J01MA12
ATC
levofloxacin; systemic
2.0
26.1
360
1933
TJF80
NOMESCO Finland
Ostomy education
9.7
26.0
53
56
K52.80
ICD-10 Finland
(Hemorrhagic) colitis caused by antibiotics
263.7
25.7
26
*
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
7.8
25.3
59
78
WX402
NOMESCO Finland
General anaesthesia
2.0
25.0
365
2002
WVA20
NOMESCO Finland
Medicine administration
5.4
24.9
76
145
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
8.3
24.7
55
68
M45
ICD-10 Finland
Ankylosing spondylitis
5.0
24.6
80
164
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.2
24.6
264
1272
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
11.8
24.5
45
39
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
11.2
24.4
46
42
UJF02
NOMESCO Finland
Peroral enteroscopy
18.8
24.4
37
20
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.6
24.3
191
785
M09.2*K51.9
ICD-10 Finland
Juvenile arthritis in ulcerative colitis
+∞
24.0
23
*
SPAT1263
SPAT
Sampling
1.6
23.6
837
6070
K61.0
ICD-10 Finland
Anal abscess
5.5
23.5
70
130
H02AB04
ATC
methylprednisolone; systemic
2.1
23.4
294
1517
SPAT1262
SPAT
Handing over of treatment supplies
2.0
22.9
344
1900
K60.3
ICD-10 Finland
Anal fistula
4.9
22.9
76
160
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
6.3
22.8
61
99
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.0
22.8
138
484
M05BA04
ATC
alendronic acid; oral
3.0
22.8
136
472
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
40.5
22.7
28
7
3005
Kela drug reimbursment
Tofacitinib
35.4
22.1
28
8
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.5
21.8
182
772
1490
FHL
Sigmoideoscopy (fiberscope)
39.1
21.7
27
7
K56.0
ICD-10 Finland
Paralytic ileus
11.6
21.7
40
35
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.1
21.3
84
210
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
20.8
536
3533
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.3
20.8
212
992
A02BC05
ATC
esomeprazole; systemic
1.6
20.6
750
5419
UJD02
NOMESCO Finland
Gastroscopy
3.3
20.2
106
337
5586X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis[KROONINEN INFLAMMATOORINEN SUOLISTOSAIRAUS, NUD]
+∞
19.8
19
*
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.6
19.7
770
5648
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
13.3
19.7
34
26
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.2
19.6
106
344
JF2AB
NOMESCO Finland
Colongraphy with X-ray
40.5
19.5
24
6
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
19.3
187
853
JJC00
NOMESCO Finland
Allogenic transplantation of liver
26.3
19.1
26
10
JHD00
NOMESCO Finland
Anal dilatation
9.9
19.1
38
39
6410
FHL
Panprococolectomy and ileostomy
+∞
18.8
18
*
JGB40
NOMESCO Finland
Excision of rectum and end ileostomy
+∞
18.8
18
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.5
18.7
156
659
UJF34
NOMESCO Finland
Left colonoscopy
10.4
18.6
36
35
Z94.4
ICD-10 Finland
Liver transplant status
16.3
18.3
29
18
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.5
18.3
143
586
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
13.7
18.2
31
23
L04AA29
ATC
tofacitinib; oral
26.9
17.8
24
9
L04AA33
ATC
vedolizumab; parenteral
+∞
17.7
17
*
1380
FHL
Colonoscopy, left side
+∞
17.7
17
*
56399
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Other
+∞
17.7
17
*
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
8.1
17.5
39
49
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.8
17.0
109
397
J01DB01
ATC
cefalexin; oral
1.6
16.9
1653
14693
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.1
16.8
96
324
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
7.5
16.7
39
53
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
+∞
16.7
16
*
5552A
ICD-9 Finland
Regional enteritis, Small intestine with large intestine
+∞
16.7
16
*
5761C
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SCLEROSIVA]
+∞
16.7
16
*
D16
ICPC
Rectal bleeding
4.5
16.6
59
135
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
27.8
16.5
22
8
E86
ICD-10 Finland
Volume depletion
5.0
16.2
52
107
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
16.1
717
5359
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
16.1
391
2509
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
24.7
16.0
22
9
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
15.9
882
6902
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
4.2
15.9
61
150
A03CA02
ATC
clidinium and psycholeptics; oral
2.8
15.7
101
369
JFG50
NOMESCO Finland
Laparotomy with revision of enterostomy or colostomy
+∞
15.6
15
*
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
19.4
15.5
23
12
JF1AD
NOMESCO Finland
Small bowel CT
13.8
15.5
26
19
A02BA02
ATC
ranitidine; systemic
1.7
15.1
316
1939
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.1
15.0
177
886
SPAT1255
SPAT
Intravenous administration of medicine
2.4
14.9
128
552
0093A
ICD-9 Finland
Ill-defined intestinal infections, Diarrhoea of presumed infectious origin
5.7
14.8
42
75
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
14.8
253
1455
K60.4
ICD-10 Finland
Rectal fistula
31.9
14.8
19
6
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
16.6
14.8
23
14
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.4
14.7
128
554
JFH00
NOMESCO Finland
Total colectomy and ileorectal anastomosis
18.5
14.7
22
12
J02AC01
ATC
fluconazole; systemic
1.5
14.5
731
5576
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
12.6
14.4
25
20
D11
ICPC
Diarrhoea
1.9
14.3
234
1324
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
14.5
14.0
23
16
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
13.9
358
2326
UJH02
NOMESCO Finland
Anoscopy
2.8
13.9
87
314
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.0
13.7
194
1041
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.1
13.7
165
832
D64.9
ICD-10 Finland
Anaemia, unspecified
2.1
13.7
154
755
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
13.6
181
951
Z43.2
ICD-10 Finland
Attention to ileostomy
34.2
13.5
17
5
5604
FHL
Vascular preparation or cannulation in the operating room
25.9
13.4
18
7
TPH05
NOMESCO Finland
Open cannulation of peripheral vein
7.8
13.4
30
39
SPAT1125
SPAT
Stoma care and guidance
6.2
13.3
35
57
J01DA01
ATC
[U] cefalexin; systemic
1.4
13.3
1197
10151
E0000UV
ATC
NA
1.4
13.2
724
5592
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
4.1
13.2
51
128
B80
ICPC
Iron deficiency anaemia
4.0
12.9
50
126
WW200
NOMESCO Finland
Immunization
3.1
12.6
68
223
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
5.1
12.6
39
78
JFA38
NOMESCO Finland
Endoscopic dilatation of small intestine
+∞
12.5
12
*
56902
ICD-8 Finland
Other diseases of intestines and peritoneum, Proctitis haemorrhagica (ulcerosa)
+∞
12.5
12
*
B03BA03
ATC
hydroxocobalamin; parenteral
2.6
12.5
93
372
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
7.3
12.5
29
40
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
12.5
317
2052
K55.9
ICD-10 Finland
Vascular disorder of intestine, unspecified
20.2
12.5
18
9
B01AB10
ATC
tinzaparin; parenteral
2.3
12.4
119
542
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
13.2
12.4
21
16
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.4
12.4
110
482
R4190
NOMESCO Finland
Nutritional therapy
2.9
12.3
76
271
ZXC86
NOMESCO Finland
Use of endoscopic device
8.0
12.3
27
34
K76.9
ICD-10 Finland
Liver disease, unspecified
5.1
12.3
38
76
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
37.8
12.2
15
*
M81.4
ICD-10 Finland
Drug-induced osteoporosis
12.5
12.1
21
17
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.6
12.0
86
336
D99
ICPC
Disease digestive system other
5.8
11.9
33
58
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.6
11.9
89
357
D18
ICPC
Change in faeces/bowel movements
3.9
11.9
48
126
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
7.1
11.8
28
40
JFA70
NOMESCO Finland
Suture of small intestine
14.7
11.8
19
13
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.8
11.6
76
281
K62.4
ICD-10 Finland
Stenosis of anus and rectum
23.0
11.6
16
7
K74.3
ICD-10 Finland
Primary biliary cirrhosis
8.7
11.5
24
28
JFG96
NOMESCO Finland
Other operation on intestinal stoma or pouch
+∞
11.5
11
*
5551A
ICD-9 Finland
Regional enteritis, Large intestine
+∞
11.5
11
*
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
13.7
11.4
19
14
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
11.4
216
1283
A07AA02
ATC
nystatin; oral
2.2
11.3
109
499
JHD33
NOMESCO Finland
Completing incision of fistula-in-ano
15.1
11.3
18
12
WX892
NOMESCO Finland
Monitored bed care
2.1
11.3
130
645
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
4.0
11.2
43
108
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
11.2
756
6027
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
20.1
11.1
16
8
127
Kela drug reimbursment
Transplant complication
4.2
11.0
41
100
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.9
11.0
64
222
WZC30
NOMESCO Finland
Teaching
1.7
10.9
221
1338
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.1
10.8
129
647
WW500
NOMESCO Finland
Blood transfusion
2.7
10.8
74
284
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
10.8
201
1185
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.2
10.8
111
525
D07AC01
ATC
betamethasone; topical
1.4
10.8
590
4519
R53
ICD-10 Finland
Malaise and fatigue
1.6
10.7
334
2271
6525
FHL
Enterostomy occlusion
28.2
10.7
14
5
N03AX16
ATC
pregabalin; oral
1.5
10.7
385
2707
JFA76
NOMESCO Finland
Closure of fistula of small intestine
60.3
10.6
12
*
Z93.3
ICD-10 Finland
Colostomy status
7.3
10.5
24
33
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
3.3
10.4
51
157
JF1CM
NOMESCO Finland
Small bowel extensive MRI with with high intensity magnet
110.5
10.4
11
*
6408
FHL
Colectomy and ileostomy
+∞
10.4
10
*
M09.1*K50.9
ICD-10 Finland
Juvenile arthritis in Crohn's disease [regional enteritis]
+∞
10.4
10
*
K65.0
ICD-10 Finland
Acute peritonitis
5.6
10.4
29
52
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
3.6
10.4
45
126
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
10.4
201
1202
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
10.3
491
3660
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
18.9
10.3
15
8
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
10.1
10.0
19
19
SPAT1153
SPAT
Removal of sutures
1.4
10.0
503
3785
K91.8
ICD-10 Finland
Other postprocedural disorders of digestive system, not elsewhere classified
40.3
10.0
12
*
D06BX01
ATC
metronidazole; topical
1.8
9.9
184
1087
WX704
NOMESCO Finland
Intubation
2.0
9.8
123
632
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
4.8
9.6
31
66
A04.9
ICD-10 Finland
Bacterial intestinal infection, unspecified
7.8
9.6
21
27
E000001
ATC
NA
1.5
9.6
368
2616
UKC02
NOMESCO Finland
Cystoscopy
1.7
9.6
224
1415
7200A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Ankylosing spondylitis
10.1
9.5
18
18
JFF11
NOMESCO Finland
Laparoscopic loop enterostomy
15.1
9.5
15
10
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
9.5
251
1637
K52.0
ICD-10 Finland
Gastroenteritis and colitis due to radiation
100.5
9.4
10
*
5589X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis, Other and unspecified non-infectious gastro-enteritis and colitis
+∞
9.4
9
*
JFH01
NOMESCO Finland
Laparoscopic colectomy with ileorectal anastomosis
+∞
9.4
9
*
5563A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctosigmoiditis
+∞
9.4
9
*
JF1DM
NOMESCO Finland
Very extensive MRI of small bowel (more than 1.5 T)
+∞
9.4
9
*
K61.1
ICD-10 Finland
Rectal abscess
9.5
9.3
18
19
JHD20
NOMESCO Finland
Incision of fistula-in-ano
4.4
9.2
32
74
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
5.7
9.2
25
44
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
9.2
274
1843
QBE15
NOMESCO Finland
Excision of other superficial lesion of skin of trunk
7.8
9.1
20
26
K83.1
ICD-10 Finland
Obstruction of bile duct
4.6
9.1
30
66
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.3
9.0
80
352
XJW99
NOMESCO Finland
Other investigative procedure on digestive system
9.1
9.0
18
20
Z50.1
ICD-10 Finland
Other physical therapy
2.1
8.9
95
457
C05AA01
ATC
hydrocortisone; rectal, topical
2.2
8.9
85
389
XQ802
NOMESCO Finland
Epicutan test
2.3
8.9
79
349
A02BA04
ATC
nizatidine; systemic
2.0
8.8
118
620
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.9
8.8
120
638
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
8.8
309
2158
D07AD01
ATC
clobetasol; topical
1.6
8.7
252
1680
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
8.7
578
4547
JFB30
NOMESCO Finland
Right hemicolectomy
4.9
8.7
27
56
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.7
8.7
193
1202
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
8.7
693
5625
M25.5
ICD-10 Finland
Pain in joint
1.4
8.6
485
3712
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.2
8.6
86
404
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
8.6
533
4148
JFK10
NOMESCO Finland
Freeing of adhesions in intestinal obstruction
11.6
8.6
15
13
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.0
8.5
108
559
K63.9
ICD-10 Finland
Disease of intestine, unspecified
9.0
8.5
17
19
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
90.4
8.4
9
*
N02AA05
ATC
oxycodone; systemic
1.7
8.4
195
1226
L88
ICD-10 Finland
Pyoderma gangrenosum
12.8
8.4
14
11
SPAT1104
SPAT
Monitoring of emergency patient
2.0
8.3
108
562
JFG70
NOMESCO Finland
Conversion of continent ileostomy to conventional ileostomy
+∞
8.3
8
*
4AC05
NOMESCO Finland
NA
+∞
8.3
8
*
K29.3
ICD-10 Finland
Chronic superficial gastritis
2.7
8.3
53
197
D01
ICPC
Abdominal pain/cramps general
1.7
8.3
189
1184
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
3.3
8.2
39
119
WX720
NOMESCO Finland
Own respiration
2.3
8.2
70
305
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
8.2
1262
11222
J01MA01
ATC
ofloxacin; systemic
1.8
8.2
134
758
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.1
8.2
85
405
SPAT1260
SPAT
Consultation of another employee
1.5
8.2
287
1997
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
8.2
1611
17232
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.4
8.2
439
3329
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
8.2
288
2009
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
8.1
373
2745
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.5
8.1
60
244
K52.2
ICD-10 Finland
Allergic and dietetic gastroenteritis and colitis
33.5
8.1
10
*
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
6.8
8.1
19
28
B01AA03
ATC
warfarin; systemic
1.6
8.0
240
1612
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
10.1
8.0
15
15
A06AC51
ATC
ispaghula, combinations; systemic
2.1
7.9
83
396
S18
ICPC
Laceration/cut
1.3
7.9
660
5370
K85
ICD-10 Finland
Acute pancreatitis
3.3
7.9
37
112
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
3.2
7.9
39
123
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.9
7.9
117
644
R06.0
ICD-10 Finland
Dyspnoea
1.4
7.9
361
2654
B07.9
ICD-10 Finland
Verruca simplex
2.4
7.9
64
271
N05CF01
ATC
zopiclone; oral
1.4
7.8
484
3761
R11
ICD-10 Finland
Nausea and vomiting
1.8
7.8
125
704
SPAT1254
SPAT
Administration of medicine
1.6
7.8
215
1419
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.3
7.8
70
315
JWF00
NOMESCO Finland
Reoperation for insufficiency of anastomosis or suture in gastroenterological surgery
15.1
7.7
12
8
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.5
7.7
55
220
E000003
ATC
NA
2.1
7.7
86
424
JKA20
NOMESCO Finland
Cholecystectomy
2.8
7.7
46
166
J01FA10
ATC
azithromycin; systemic
1.3
7.6
1113
9780
L04AA06
ATC
mycophenolic acid; systemic
3.1
7.6
39
127
JWW96
NOMESCO Finland
Other reoperation in gastroenterological surgery
18.4
7.6
11
6
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
7.6
182
1157
JX1LA
NOMESCO Finland
Kinetic X-ray of alimentary tract with pictures
25.1
7.6
10
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.9
7.6
104
555
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
7.5
215
1427
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
3.1
7.5
39
128
C10AC02
ATC
colestipol; oral
10.1
7.5
14
14
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
2.5
7.5
56
228
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.0
7.5
87
435
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
7.5
275
1934
A01AB09
ATC
miconazole; local oral
1.7
7.5
137
806
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.7
7.4
48
180
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.7
7.4
152
926
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
7.7
7.4
16
21
JG1JB
NOMESCO Finland
Defekography with X-ray
6.0
7.4
19
32
ZX100
NOMESCO Finland
Oral
3.9
7.4
28
72
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
7.3
482
3775
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.8
7.3
114
638
N18.8
ICD-10 Finland
Other chronic renal failure
2.8
7.3
43
153
D07AC13
ATC
mometasone; topical
1.4
7.3
485
3804
6437
FHL
Rectum resection and sphincter-sparing through-anastomosis
+∞
7.3
7
*
JGB61
NOMESCO Finland
Laparoscopic excision of rectum and ileoanal anastomosis
+∞
7.3
7
*
WX110
NOMESCO Finland
Local anesthesy
1.3
7.3
1327
11971
R10.0
ICD-10 Finland
Acute abdomen
2.4
7.3
60
256
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.8
7.2
122
700
JAD10
NOMESCO Finland
Repair of incisional hernia
5.8
7.2
19
33
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.5
7.2
220
1488
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.8
7.2
114
640
JGB96
NOMESCO Finland
Other proctectomy or excision of rectum
30.1
7.1
9
*
K86.1
ICD-10 Finland
Other chronic pancreatitis
4.8
7.1
22
46
JJ5AT
NOMESCO Finland
NA
20.1
7.1
10
5
A10AE05
ATC
insulin detemir; parenteral
1.9
7.0
96
516
SPAT1325
SPAT
Vaccination
1.3
7.0
505
4009
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
3.3
6.9
32
97
J05AB01
ATC
aciclovir; systemic
1.4
6.9
343
2554
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.5
6.9
52
214
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
6.8
1001
8750
71240
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Spondylitis ankylopoietica
9.3
6.8
13
14
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
6.8
279
2008
B02.9
ICD-10 Finland
Zoster without complication
2.0
6.7
79
398
J01MA14
ATC
moxifloxacin; systemic
1.7
6.7
140
858
JAH01
NOMESCO Finland
Laparoscopy
2.0
6.7
81
414
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
4.1
6.7
24
59
SPAT1312
SPAT
General health counselling
1.3
6.7
554
4488
K45.8
ICD-10 Finland
Other specified abdominal hernia without obstruction or gangrene
6.4
6.6
16
25
M13.9
ICD-10 Finland
Arthritis, unspecified
1.8
6.6
115
670
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
6.6
258
1840
J01FF01
ATC
clindamycin; systemic
1.3
6.6
441
3460
ZX121
NOMESCO Finland
Central venous catheter
8.7
6.5
13
15
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.0
6.5
82
427
K90.0
ICD-10 Finland
Coeliac disease
2.4
6.5
53
228
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
4.1
6.5
23
56
L88
ICPC
Rheumatoid/seropositive arthritis
2.3
6.5
58
260
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
6.5
222
1537
J01FA06
ATC
roxithromycin; oral
1.3
6.5
687
5752
A12BA01
ATC
potassium chloride; oral
2.4
6.5
50
210
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
6.2
6.5
16
26
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.3
6.5
55
241
R01AD08
ATC
fluticasone; nasal
1.3
6.5
498
3989
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
2.8
6.4
39
143
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
2.2
6.4
58
262
N82.4
ICD-10 Finland
Other female intestinal-genital tract fistulae
70.1
6.4
7
*
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.9
6.4
83
435
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
6.4
161
1039
M02AA07
ATC
piroxicam; topical
1.3
6.4
531
4297
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
14.3
6.4
10
7
N82.3
ICD-10 Finland
Fistula of vagina to large intestine
14.3
6.4
10
7
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
6.3
295
2173
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.6
6.3
143
897
WX004
NOMESCO Finland
Patient-controlled sedation
6.0
6.3
16
27
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
11.0
6.3
11
10
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.6
6.3
155
995
A07AA11
ATC
rifaximin; oral
9.3
6.3
12
13
C03CA01
ATC
furosemide; systemic
1.4
6.3
317
2370
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.6
6.2
167
1095
TGC00
NOMESCO Finland
Bronchial lavation
2.5
6.2
44
175
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.7
6.1
119
714
JH1CM
NOMESCO Finland
Perianal extensive MRI with 3 Tesla magnet
12.5
6.1
10
8
K91.2
ICD-10 Finland
Postsurgical malabsorption, not elsewhere classified
12.5
6.1
10
8
N70.1
ICD-10 Finland
Chronic salpingitis and oophoritis
3.9
6.1
23
60
JHA20
NOMESCO Finland
Excision of lesion of anal canal or perianal tissue
3.9
6.1
23
60
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
6.1
165
1085
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.3
6.1
50
217
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.6
6.1
40
154
JJA20
NOMESCO Finland
Open biopsy of liver
8.6
6.1
12
14
H25.8
ICD-10 Finland
Other senile cataract
1.8
6.0
105
612
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.4
6.0
47
199
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1903
9494
6.36
312.04
15.1
5.9
0.2
0.2
e9/l
0.00
1795
8411
281
17
187.69
307.65
3.6
2.5
8.0
6.0
mg/l
0.93
238
12
512
510
12.57
307.65
1.7
1.5
10.8
0.1
iu/ml
0.59
117
89
1699
7128
6.04
307.65
4.2
2.1
73.8
74.8
nmol/l
0.82
1644
6498
1789
1954
35.54
307.65
7.7
1.3
244.0
87.6
ug/g
38.98
1707
1487
256
18
159.55
307.65
3.0
2.5
71.3
252.0
au/ml
—
37
5
1863
6963
9.19
307.65
11.7
4.5
36.3
36.2
g/l
0.75
1819
6490
803
963
12.17
307.65
2.4
1.5
—
—
—
0
0
626
1279
6.32
306.39
6.3
3.9
0.4
0.7
%
2.21
136
285
1889
9453
6.16
305.93
14.9
5.6
1.8
2.0
e9/l
2.92
1801
8409
1778
8559
5.47
299.62
14.8
5.7
2.8
2.8
%
0.12
1711
7997
1790
8802
5.39
289.49
14.1
5.6
57.4
56.7
%
1.92
1728
8274
1799
8928
5.38
286.15
15.0
5.7
28.3
28.6
%
0.92
1736
8367
1932
10566
5.73
259.91
17.2
8.8
4.0
4.1
e9/l
1.60
1838
9264
2207
13759
11.48
248.36
19.9
6.8
77.7
76.1
u/l
0.94
2161
12967
1090
4086
4.12
245.00
4.2
2.0
3.1
2.9
mg/l
3.13
1009
3487
298
361
9.31
232.59
4.0
6.8
792.9
400.5
iu/ml
0.68
44
50
135
33
43.35
225.39
2.5
1.3
9.5
8.8
mg/l
0.27
112
26
2024
13511
4.67
160.70
8.5
3.7
12.7
10.4
mm/h
11.62
1914
12602
642
2149
3.74
160.29
3.1
2.5
20.6
24.3
%
8.18
549
1850
161
148
11.61
152.41
2.3
1.2
—
—
—
0
0
222
323
7.49
147.14
5.7
3.4
57.9
56.4
%
0.82
222
323
218
311
7.63
147.05
5.6
3.1
4.0
4.1
e9/l
0.47
218
311
688
2543
3.41
145.69
3.1
2.4
12.2
14.0
umol/l
8.51
671
2355
652
2331
3.49
145.60
3.1
2.4
2.4
2.4
g/l
3.28
632
2165
1213
6270
2.94
141.68
6.0
3.2
30.9
34.6
u/l
0.74
1140
5986
1099
5470
2.90
136.42
4.8
2.5
62.4
56.4
u/l
1.91
1054
5068
1524
9050
2.96
134.72
9.8
6.0
10.3
11.4
umol/l
4.15
1476
8591
208
320
7.04
130.73
1.6
1.4
—
—
—
0
0
1415
8191
2.84
129.25
18.6
8.7
0.0
0.0
e9/l
1.01
1310
6703
118
0
+∞
124.07
3.1
0.0
22.4
—
mg/l
—
113
0
384
1062
4.13
123.77
2.2
1.8
1.3
1.4
g/l
0.55
362
978
116
0
+∞
121.95
3.1
0.0
—
—
—
0
0
440
1378
3.70
118.40
3.0
2.6
11.8
10.5
g/l
6.93
415
1262
213
375
6.15
117.14
1.5
1.2
—
—
—
0
0
457
1530
3.47
110.49
4.1
2.2
0.2
0.2
g/l
1.89
432
1424
179
286
6.69
108.23
2.5
1.6
0.9
0.9
g/l
0.02
150
215
1385
8385
2.60
108.16
4.5
2.7
108.8
116.5
ug/l
0.36
1325
7855
1156
6534
2.52
102.89
10.6
7.8
1.1
1.2
inr
2.20
428
2015
112
119
9.83
95.42
2.6
1.3
—
—
—
0
0
230
524
4.76
94.41
5.7
3.4
65.9
2796.9
u/ml
0.81
210
447
116
135
8.99
92.21
1.6
1.1
360.4
150.5
titre
1.59
49
20
116
135
8.99
92.21
1.6
1.1
245.0
314.0
titre
—
6
5
235
591
4.31
84.90
2.2
1.5
386.1
281.4
titre
0.20
23
14
196
436
4.81
82.60
2.0
1.2
4.4
6.9
iu/ml
—
6
7
1283
8233
2.23
77.66
8.7
6.6
1.2
1.2
mmol/l
0.34
1092
6995
255
728
3.81
77.15
1.9
1.5
4.8
27.5
u/ml
1.29
35
17
182
424
4.57
72.31
1.3
1.3
—
—
—
0
0
2263
19253
6.20
70.96
31.3
11.8
16.3
22.7
mg/l
29.89
2072
14906
174
405
4.56
69.16
1.4
1.3
278.4
256.3
u/ml
0.34
92
254
131
241
5.70
68.33
4.1
2.8
6.1
75.1
u/ml
0.68
131
220
560
2680
2.43
66.46
2.1
1.7
1170.0
1179.4
nmol/l
0.07
428
2084
652
3404
2.27
62.80
2.3
1.6
18664818.0
43763417.8
pmol/l
0.59
584
2886
39
11
36.04
62.03
1.0
1.0
—
—
—
0
0
207
600
3.69
60.90
1.9
1.8
—
—
—
0
0
1461
10431
2.07
60.39
6.3
4.7
6.6
6.6
mmol/l
0.01
1375
9681
106
180
6.12
60.03
1.8
1.5
—
—
—
0
0
1039
6600
2.03
59.19
2.1
1.8
97.0
96.6
pmol/l
0.09
662
3555
106
184
5.99
58.70
1.8
1.5
—
—
—
0
0
120
239
5.24
57.31
1.4
1.3
—
—
—
0
0
120
240
5.22
57.04
3.2
3.5
1.4
1.7
%
0.31
96
205
103
179
5.97
56.96
1.8
1.5
—
—
—
0
0
104
184
5.87
56.46
1.8
1.5
—
—
—
0
0
103
181
5.91
56.31
1.8
1.5
—
—
—
0
0
103
181
5.91
56.31
1.8
1.5
—
—
—
0
0
355
1477
2.65
55.85
5.9
4.2
6.3
24.0
ug/l
1.80
285
1195
65
81
8.23
48.77
25.1
27.0
128.0
125.1
ug/l
0.09
60
64
87
150
5.99
48.48
1.7
1.5
11.2
11.7
umol/l
0.31
87
140
1045
6998
1.89
47.89
4.7
3.3
—
—
—
0
0
1095
7458
1.88
47.46
7.3
5.9
1.2
1.2
mmol/l
0.00
1022
6796
666
3861
2.01
46.67
2.0
1.4
2.5
2.3
g/l
1.95
513
2456
122
300
4.24
45.00
5.7
3.8
23.5
1292.2
u/ml
0.87
112
281
84
153
5.66
44.20
1.3
1.2
77.0
57.4
u/l
0.61
56
106
413
2036
2.25
43.99
9.8
7.4
104.8
104.4
mmol/l
1.31
408
1991
372
1760
2.32
43.66
2.6
2.2
325.8
374.0
nmol/l
5.00
352
1633
200
701
3.03
43.03
5.7
3.4
25.0
25.2
mmol/l
0.34
194
678
323
1452
2.42
42.52
6.0
3.8
1.8
2.0
mmol/l
0.32
261
1159
1237
8959
1.81
42.12
4.4
3.3
0.0
0.0
estimate
0.80
330
1637
323
1459
2.41
42.04
6.0
3.8
5.8
5.9
kpa
0.40
315
1414
108
256
4.37
41.77
1.2
1.1
1.5
1.5
g/l
0.56
99
228
1244
9067
1.79
41.05
4.6
3.3
0.0
0.0
estimate
0.80
338
1603
398
1986
2.21
40.92
5.5
2.7
6.5
7.9
umol/l
1.30
362
1727
1231
8980
1.78
40.16
6.3
4.5
0.0
0.0
estimate
0.50
345
1682
2079
17973
2.40
39.85
23.7
10.7
87.9
87.3
ml/min/173m2
0.62
1879
14758
2263
20465
4.14
39.05
31.7
13.4
78.9
75.6
umol/l
3.82
2263
20458
178
632
2.97
37.34
4.8
5.1
1.6
1.7
%
0.61
173
590
2266
20583
4.11
37.28
25.2
9.0
27.8
27.8
u/l
0.02
2245
19948
342
1679
2.21
36.32
3.6
2.4
45.1
67.6
u/l
0.36
318
1434
1928
16392
2.00
35.29
32.5
14.5
13.8
13.5
%
13.91
1920
16048
1170
8620
1.71
35.01
5.6
3.9
—
—
—
0
0
108
294
3.80
34.62
1.1
1.1
—
—
—
0
0
206
837
2.60
33.35
3.3
2.7
0.4
0.2
e6/l
0.96
201
811
263
1200
2.34
33.12
5.2
3.1
4.5
4.7
kpa
1.04
256
1158
2149
19228
2.43
31.56
24.1
13.3
139.3
139.7
mmol/l
12.30
2112
18735
45
61
7.50
31.43
1.9
2.4
9705.3
34353.1
u/ml
—
6
14
62
118
5.37
31.12
1.2
1.2
—
—
—
0
0
62
118
5.37
31.12
1.2
1.2
—
—
—
0
0
219
946
2.45
31.12
5.2
3.1
129.6
131.3
g/l
0.50
209
922
580
3613
1.80
30.60
1.6
1.5
19.8
20.4
nmol/l
0.43
521
3143
2151
19304
2.40
30.48
24.2
13.4
3.9
4.0
mmol/l
7.13
2111
18774
144
511
2.94
30.18
1.5
1.1
—
—
—
0
0
143
508
2.93
29.91
1.5
1.1
—
—
—
0
0
51
86
6.04
29.06
1.4
1.1
100.5
75.5
u/l
0.97
43
72
46
73
6.41
27.83
1.5
1.4
—
—
—
0
0
46
74
6.32
27.46
1.5
1.4
—
—
—
0
0
118
395
3.09
27.39
1.4
1.5
122.6
120.2
u/ml
0.04
25
80
52
95
5.58
27.29
1.7
1.5
6.6
7.7
u/l
0.14
30
45
314
1669
2.02
26.62
3.7
2.8
1.9
1.8
%
0.82
285
1501
697
4733
1.67
26.37
4.7
3.6
0.0
0.0
estimate
1.28
333
1621
57
117
4.97
26.30
1.1
1.0
—
—
—
0
0
48
85
5.74
26.03
1.4
1.1
42.5
16.4
u/l
0.84
40
70
98
304
3.32
25.80
2.9
3.0
160.0
1244.9
u/ml
0.66
11
17
453
2752
1.80
25.44
5.6
3.6
0.8
0.8
mmol/l
1.36
421
2597
282
1479
2.03
24.73
11.4
8.0
9.3
8.8
mmol/l
0.53
272
1423
258
1316
2.08
24.39
5.2
3.5
1.2
1.2
mmol/l
0.01
239
1138
39
60
6.59
24.30
1.6
1.5
—
—
—
0
0
39
60
6.59
24.30
1.6
1.5
—
—
—
0
0
376
2189
1.85
24.16
9.0
6.1
1.0
1.0
mmol/l
0.11
361
2046
150
610
2.56
24.15
2.3
2.1
10.2
1.7
ug/l
0.44
137
548
62
149
4.25
23.59
3.1
3.4
58.8
53.1
%
1.00
39
107
321
1803
1.90
22.99
3.2
4.4
228.0
245.2
u/l
1.25
306
1720
162
706
2.39
22.47
1.3
1.4
—
—
—
0
0
680
4750
1.61
22.28
3.7
2.9
0.5
0.4
e6/l
0.24
573
3530
46
93
5.03
21.62
1.1
1.1
1419.5
1587.7
miu/ml
0.48
46
93
1425
11789
1.53
21.43
4.9
3.9
384.8
1709.5
e6/l
1.13
18
152
535
3555
1.65
21.30
3.0
2.5
6.2
6.2
e6/l
0.01
492
3119
854
6343
1.55
21.19
3.7
3.2
46.5
46.6
ng/l
0.00
547
3893
116
445
2.69
21.00
1.5
1.4
288.4
298.6
ug/g
0.20
70
241
153
677
2.35
20.50
1.6
2.0
1.5
1.5
g/l
0.21
137
598
319
1861
1.83
20.14
20.6
20.2
1.3
1.2
inr
0.02
69
282
32
49
6.61
20.03
1.2
1.2
—
—
—
0
0
127
523
2.51
19.92
5.1
3.9
1.4
1.4
mg/l
0.07
116
487
411
2590
1.71
19.86
2.2
1.8
—
—
—
0
0
156
714
2.27
19.31
4.0
2.7
0.7
0.7
%
0.72
151
693
34
59
5.83
18.85
1.1
1.3
—
—
—
0
0
23
26
8.92
18.55
1.9
1.2
—
—
—
0
0
205
1061
2.02
18.50
1.7
1.4
—
—
—
0
0
293
1740
1.78
17.31
3.9
3.1
—
—
—
0
0
193
1001
2.01
17.31
6.9
7.2
23.8
24.4
mmol/l
1.61
177
934
615
4434
1.52
16.68
1.3
1.3
0.9
1.6
u/ml
2.45
167
1246
303
1837
1.75
16.64
8.5
8.1
0.9
1.0
mmol/l
0.15
215
1434
303
1837
1.75
16.64
8.5
8.1
4.9
5.1
kpa
3.44
283
1759
303
1838
1.74
16.60
8.4
8.1
12.3
12.6
kpa
0.47
284
1763
56
162
3.52
16.51
1.1
1.0
291.0
287.1
mg/l
0.13
48
144
101
410
2.53
16.35
7.1
2.9
24.1
24.8
mmol/l
0.89
87
366
29
50
5.86
16.19
1.2
1.2
—
—
—
0
0
196
1053
1.94
15.87
5.8
3.6
5.1
5.2
kpa
0.92
185
988
410
2724
1.61
15.84
3.3
2.8
3.0
2.5
e6/l
0.58
274
1444
595
4332
1.50
15.18
3.2
2.2
—
—
—
0
0
2286
21875
2.88
14.88
41.4
17.5
273.3
253.1
e9/l
33.85
2266
21371
99
420
2.42
14.61
1.8
1.7
—
—
—
0
0
2286
21901
2.83
14.35
41.2
17.4
4.5
4.6
e12/l
23.09
2260
21352
575
4205
1.49
14.22
1.8
1.8
1.2
1.0
mg/l
0.77
445
3117
254
1530
1.74
14.19
9.6
8.8
120.7
124.1
g/l
1.77
243
1478
2286
21909
2.82
14.19
41.5
17.5
134.5
137.7
g/l
22.60
2276
21638
2285
21908
2.77
13.92
41.4
17.5
6.9
6.7
e9/l
2.71
2258
21360
183
1006
1.89
13.82
5.9
3.6
1.3
1.6
mmol/l
0.55
135
744
164
871
1.95
13.73
12.2
11.0
—
—
—
0
0
418
2884
1.55
13.55
3.1
2.6
1.2
1.1
e6/l
0.22
281
1601
93
414
2.30
12.35
1.9
1.7
—
—
—
0
0
42
123
3.46
12.22
1.6
2.0
—
—
—
0
0
25
49
5.15
12.21
1.1
1.3
—
—
—
0
0
1551
13731
1.38
11.94
5.7
3.0
61.3
45.2
u/l
9.47
1486
13004
60
222
2.75
11.76
1.4
1.3
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
103
489
2.16
11.72
3.3
3.3
0.3
0.4
u/ml
1.08
60
267
711
5604
1.39
11.20
4.3
3.3
2.3
2.4
mmol/l
5.47
633
4996
114
576
2.03
11.03
1.5
1.6
1.2
1.2
g/l
0.17
102
545
30
76
3.99
10.76
3.8
3.2
—
—
—
0
0
110
554
2.03
10.74
1.5
1.6
0.2
0.2
g/l
1.68
98
525
66
274
2.45
10.30
1.5
1.4
—
—
—
0
0
59
238
2.52
9.79
1.6
1.4
—
—
—
0
0
269
1802
1.56
9.79
2.0
1.7
—
—
—
0
0
21
43
4.92
9.79
1.1
2.0
—
—
—
0
0
266
1778
1.56
9.78
1.9
1.7
—
—
—
0
0
81
378
2.18
9.67
4.3
3.2
30.1
36.4
umol/l
1.53
71
333
141
800
1.81
9.66
5.9
4.0
24.0
24.1
mmol/l
0.24
132
732
111
583
1.95
9.66
2.0
1.8
—
—
—
0
0
66
284
2.36
9.54
2.6
2.3
21.2
5.9
umol/l
1.67
54
204
76
350
2.21
9.38
3.5
2.5
16.4
16.6
%
0.24
43
171
364
2622
1.46
9.34
2.2
2.3
29.2
29.7
s
1.05
350
2544
99
506
2.00
9.32
2.8
2.9
—
—
—
0
0
39
131
3.01
9.16
1.5
2.1
14.3
13.7
%
0.07
15
71
67
297
2.29
9.07
2.1
1.8
—
—
—
0
0
80
382
2.13
9.04
4.4
4.2
5.0
5.0
kpa
0.36
80
377
224
1471
1.58
8.89
9.2
7.7
1.3
1.4
mmol/l
0.50
212
1410
186
1170
1.64
8.81
4.8
4.1
88.2
84.8
ng/l
0.14
164
1056
638
5102
1.34
8.77
2.3
2.1
295.1
242.1
u/l
0.18
607
4829
79
382
2.11
8.66
7.8
3.2
8.8
8.4
kpa
1.08
72
356
163
996
1.68
8.64
1.6
1.5
—
—
—
0
0
41
147
2.82
8.60
1.3
1.3
—
—
—
0
0
415
3118
1.40
8.38
1.3
1.3
7.9
10.9
u/ml
0.54
158
1301
201
1309
1.59
8.27
1.4
1.3
224.1
213.0
u/ml
0.06
186
1219
522
4082
1.36
8.24
2.8
3.0
1546.0
1092.9
ng/l
0.95
438
3421
38
135
2.84
8.12
2.0
2.5
436.6
572.3
e6/l
0.82
28
118
117
663
1.80
8.09
2.4
1.9
—
—
—
0
0
502
3918
1.36
8.00
4.6
3.6
1.0
1.0
kg/l
0.00
107
542
72
348
2.10
7.93
1.7
1.6
—
—
—
0
0
139
834
1.71
7.89
1.9
2.0
39.9
40.0
u/l
0.01
124
758
37
132
2.83
7.86
2.0
1.9
—
—
—
0
0
74
363
2.07
7.84
3.6
2.3
125.8
131.8
g/l
1.40
62
266
104
574
1.85
7.84
2.7
2.9
3.3
3.5
g/l
0.73
99
542
67
317
2.15
7.79
1.5
1.5
—
—
—
0
0
1963
18463
1.39
7.79
26.2
12.7
38.3
40.6
%
15.43
1402
14396
414
3171
1.37
7.38
3.7
3.4
260.4
490.0
ng/l
1.66
265
2216
102
574
1.81
7.25
3.9
4.3
1.4
1.4
mmol/l
0.06
97
566
186
1234
1.55
7.07
2.1
2.7
67.2
66.9
g/l
0.17
179
1140
47
200
2.38
7.05
2.0
2.3
31.4
32.3
pg
0.58
47
200
1561
14310
1.27
6.80
3.2
3.3
—
—
—
0
0
104
601
1.76
6.78
2.1
1.8
—
—
—
0
0
35
132
2.68
6.74
1.6
1.9
—
—
—
0
0
88
488
1.83
6.59
1.7
1.7
—
—
—
0
0
422
3305
1.34
6.46
1.3
1.3
17.2
29.6
iu/ml
3.32
138
1021
43
186
2.34
6.26
1.0
1.0
—
—
—
0
0
34
132
2.60
6.21
2.0
2.6
0.2
0.2
e9/l
0.10
26
118
37
150
2.49
6.19
2.1
1.6
—
—
—
0
0
37
150
2.49
6.19
2.1
1.6
—
—
—
0
0
37
150
2.49
6.19
2.1
1.6
—
—
—
0
0
90
514
1.78
6.14
2.0
2.2
10.8
10.5
mg/l
0.10
82
478
25
83
3.03
6.07
2.2
1.9
—
—
—
0
0
25
83
3.03
6.07
2.2
1.9
—
—
—
0
0
25
83
3.03
6.07
2.2
1.9
—
—
—
0
0
25
83
3.03
6.07
2.2
1.9
—
—
—
0
0
51
243
2.12
5.91
2.0
1.6
—
—
—
0
0
74
406
1.85
5.77
1.5
2.4
0.9
0.8
nmol/l
0.37
63
351
95
564
1.71
5.69
1.1
1.1
0.7
3.9
u/ml
—
8
82
172
1186
1.49
5.50
3.4
2.8
283.1
169.6
ng/l
1.40
159
1062
31
126
2.48
5.21
2.8
2.2
1.8
2.1
u/field
0.17
16
63
143
961
1.52
5.19
2.1
2.3
5120.0
4686.8
u/l
0.05
47
377
518
4287
1.27
5.15
1.6
1.6
—
—
—
0
0
82
484
1.72
5.05
4.2
4.5
3.9
3.9
mmol/l
0.17
77
452
31
129
2.42
4.97
2.0
1.6
—
—
—
0
0
555
4652
1.25
4.92
3.0
2.5
6986.6
4258.2
umol/l
0.66
506
4112
70
400
1.77
4.84
1.3
1.2
46.0
41.7
u/ml
—
6
35
19
62
3.08
4.79
2.2
3.1
—
—
—
0
0
36
164
2.21
4.72
2.9
1.5
0.9
1.0
g/l
1.17
36
164
40
191
2.11
4.68
1.9
1.8
—
—
—
0
0
41
199
2.08
4.60
2.0
1.7
—
—
—
0
0
582
4955
1.23
4.43
4.7
4.1
8.1
9.4
mg/mmol
0.36
405
3215
18
60
3.02
4.40
1.3
1.8
—
—
—
0
0
195
1438
1.39
4.38
4.8
2.4
63.7
72.4
ml/min/173m2
2.96
97
532
71
424
1.70
4.25
1.9
3.6
37.5
51.8
mg/l
0.46
51
336
65
382
1.72
4.13
1.2
1.2
10.7
4.4
u/ml
—
5
26
47
251
1.89
4.08
1.7
1.6
—
—
—
0
0
69
416
1.68
4.00
1.9
3.6
1.3
3.2
ratio
—
7
33
70
424
1.67
3.99
2.0
3.7
54.5
68.1
mg/l
0.37
52
336
86
549
1.59
3.98
1.3
2.3
—
—
—
0
0
86
549
1.59
3.98
1.3
2.3
4.0
3.8
g/l
1.00
46
404
86
549
1.59
3.98
1.3
2.3
7.4
7.3
g/l
0.21
50
423
36
179
2.03
3.84
2.2
1.8
—
—
—
0
0
65
391
1.68
3.82
1.9
1.7
—
—
—
0
0
112
766
1.49
3.81
1.4
1.3
197.9
219.3
miu/ml
0.22
42
374
77
488
1.60
3.70
1.3
1.2
5.7
7.1
u/ml
0.20
11
78
76
481
1.60
3.67
1.3
1.2
7.7
2.5
u/ml
—
6
48
16
56
2.87
3.63
1.3
1.4
12.7
8.8
ug/l
0.93
16
56
1557
14681
1.18
3.51
3.9
3.8
14.7
14.6
pmol/l
0.91
1446
13555
63
386
1.65
3.48
1.2
1.2
—
10.9
—
0
5
140
1024
1.39
3.36
12.5
10.5
0.7
0.7
%
0.16
135
1019
140
1028
1.38
3.28
12.0
10.3
1.3
1.4
%
1.18
135
1023
6
7
8.59
3.26
1.0
1.0
—
—
—
0
0
15
54
2.79
3.25
1.1
1.1
—
—
—
0
0
12
38
3.17
3.21
1.1
1.1
105.3
95.1
%
0.91
12
38
12
38
3.17
3.21
1.1
1.1
—
—
—
0
0
18
72
2.51
3.21
1.0
6.1
12909.5
77.5
mg/l
0.47
13
57
28
137
2.06
3.16
2.5
2.4
726.9
625.1
ml
0.33
21
95
77
508
1.53
3.16
1.4
2.4
10.7
10.3
g/l
0.28
65
437
85
574
1.50
3.13
2.4
2.8
199.8
175.1
%
1.92
80
551
34
180
1.90
3.10
1.8
1.6
44.4
57.5
%
0.88
18
116
53
325
1.65
2.97
1.1
1.1
67.6
1615.1
iu/ml
—
7
83
29
149
1.96
2.90
2.0
2.6
752.6
768.2
e6/l
0.03
18
60
17
70
2.44
2.88
2.5
2.0
—
—
—
0
0
17
70
2.44
2.88
2.5
2.0
—
—
—
0
0
12
41
2.94
2.86
1.1
1.1
—
—
—
0
0
34
186
1.84
2.83
2.4
6.5
6.3
7.2
mmol/l
0.90
24
155
21
96
2.20
2.83
1.0
1.2
—
—
—
0
0
17
71
2.40
2.80
2.5
2.0
—
—
—
0
0
41
677
0.60
2.76
1.4
1.4
—
—
—
0
0
41
676
0.60
2.74
1.4
1.4
—
—
—
0
0
41
674
0.60
2.71
1.4
1.4
—
—
—
0
0
30
160
1.89
2.71
1.3
1.3
0.4
0.6
u/ml
0.31
11
68
115
847
1.38
2.70
13.5
11.1
23.4
24.3
mmol/l
1.95
108
804
41
672
0.60
2.68
1.4
1.4
—
—
—
0
0
1818
17499
1.17
2.67
4.7
4.5
1.7
2.1
mu/l
1.81
1702
16274
9
24
3.76
2.67
2.0
1.2
—
—
—
0
0
90
637
1.43
2.66
2.0
2.5
87.8
93.0
%
1.23
85
597
24
119
2.03
2.66
1.0
1.5
4.8
6.4
u/l
1.36
19
98
10
32
3.13
2.64
1.7
1.6
—
—
—
0
0
18
82
2.20
2.47
1.2
1.1
—
—
—
0
0
60
883
0.67
2.44
1.4
1.7
3.1
4.2
mg/l
0.67
40
616
282
3328
0.83
2.36
2.9
2.8
0.7
0.7
ug/l
0.28
197
2028
9
28
3.22
2.30
2.0
2.1
—
—
—
0
0
22
112
1.97
2.30
2.0
1.6
—
—
—
0
0
80
573
1.41
2.26
2.0
2.4
307.1
300.7
ug/l
0.02
68
540
118
903
1.32
2.21
1.5
1.6
—
—
—
0
0
19
93
2.05
2.21
1.7
3.1
864.7
1224.9
u/ml
0.45
19
93
5
9
5.56
2.21
1.0
5.7
—
—
—
0
0
21
107
1.97
2.20
1.3
1.2
—
—
—
0
0
343
2966
1.18
2.16
1.8
1.9
1.4
1.4
%
1.35
290
2662
50
741
0.67
2.15
1.4
1.5
—
—
—
0
0
182
2222
0.80
2.14
1.6
1.7
—
—
—
0
0
32
189
1.70
2.13
2.7
2.1
19.0
23.2
mg/l
—
10
53
8
25
3.21
2.09
1.5
3.1
—
—
—
0
0
5
10
5.01
2.07
1.4
3.4
—
—
—
0
0
62
437
1.43
1.95
1.4
1.4
—
—
—
0
0
5
11
4.55
1.94
1.0
1.4
3.8
13.7
u/l
—
5
11
34
212
1.61
1.88
1.0
1.2
—
—
—
0
0
595
5417
1.13
1.85
3.4
3.3
8.4
8.1
mmol/l
0.90
510
4639
5
12
4.17
1.82
1.0
1.5
—
—
—
0
0
48
327
1.48
1.82
1.3
1.5
—
—
—
0
0
366
3240
1.15
1.73
1.7
1.5
—
—
—
0
0
18
96
1.88
1.70
2.2
1.6
—
—
—
0
0
404
4502
0.88
1.66
4.0
3.8
19.4
21.3
%
1.87
199
1935
47
326
1.45
1.65
1.0
1.0
0.9
2.4
u/ml
3.24
15
160
25
150
1.67
1.63
1.9
1.4
40.6
34.6
%
0.31
15
96
53
381
1.40
1.55
3.8
3.7
21.4
24.3
mg/l
0.39
42
240
14
71
1.98
1.54
2.1
2.6
—
—
—
0
0
63
838
0.74
1.52
1.4
1.4
—
—
—
0
0
5
15
3.34
1.52
1.0
1.3
—
—
—
0
0
23
138
1.67
1.51
1.1
1.1
—
33.0
—
0
7
5
126
0.40
1.49
1.4
1.3
45.1
31.7
nmol/l
—
5
106
23
140
1.65
1.45
1.1
1.2
—
61.5
—
0
10
45
319
1.42
1.44
1.5
1.7
—
—
—
0
0
5
16
3.13
1.44
1.0
1.0
—
—
—
0
0
7
154
0.45
1.42
1.7
3.4
—
—
—
0
0
17
96
1.78
1.39
2.2
1.6
—
—
—
0
0
68
520
1.32
1.38
1.3
2.4
3.1
3.1
g/l
0.19
48
412
35
239
1.47
1.37
2.2
3.1
0.8
0.8
nmol/l
0.54
25
183
6
23
2.61
1.36
1.0
1.2
—
—
—
0
0
320
2859
1.14
1.35
3.4
2.8
2.4
2.4
mmol/l
0.88
270
2527
0
37
0.00
1.34
0.0
1.1
—
—
—
0
0
0
38
0.00
1.34
0.0
1.2
—
—
—
0
0
14
76
1.85
1.29
1.9
3.2
98.7
110.6
umol/l
—
7
43
8
34
2.36
1.29
1.4
1.3
—
—
—
0
0
23
146
1.58
1.26
1.1
1.1
—
—
—
0
0
159
1360
1.18
1.22
2.3
2.4
7.3
22.9
au/ml
—
6
101
107
1288
0.82
1.19
1.4
1.5
—
—
—
0
0
8
39
2.05
1.15
19.4
5.6
—
—
—
0
0
155
1796
0.85
1.13
2.0
2.0
—
—
—
0
0
5
21
2.38
1.09
1.0
1.0
—
—
—
0
0
40
295
1.36
1.08
1.7
1.9
—
1018.2
—
0
11
34
244
1.40
1.07
1.1
1.3
—
0.4
nmol/l
—
0
18
42
313
1.35
1.06
1.1
1.1
—
—
—
0
0
77
944
0.81
1.05
1.7
1.6
320.6
287.2
mu/l
0.34
72
859
71
570
1.25
1.05
1.2
1.1
—
—
—
0
0
74
597
1.25
1.05
1.5
1.3
—
—
—
0
0
103
861
1.21
1.05
2.4
1.8
—
—
—
0
0
88
727
1.22
1.01
1.4
1.4
8.8
8.4
u/l
0.08
75
602
10
53
1.89
1.01
1.3
1.1
—
—
—
0
0
10
53
1.89
1.01
1.3
1.1
—
—
—
0
0
86
710
1.22
1.00
1.7
1.4
—
—
—
0
0
231
2069
1.13
0.98
3.9
4.0
32.6
31.4
%
0.92
185
1474
5
23
2.18
0.98
1.0
1.0
—
—
—
0
0
5
23
2.18
0.98
2.2
1.5
120.0
108.4
ng/l
—
5
23
5
23
2.18
0.98
1.0
1.0
—
—
—
0
0
0
30
0.00
0.97
0.0
1.0
—
0.1
—
0
18
9
51
1.77
0.94
4.4
2.4
—
—
—
0
0
9
51
1.77
0.94
4.4
2.4
—
—
—
0
0
131
1132
1.17
0.94
1.4
1.4
28.0
24.5
iu/l
0.56
121
953
28
203
1.38
0.87
1.8
1.4
510.0
293.3
pmol/l
0.60
22
160
6
30
2.00
0.87
1.2
1.2
—
—
—
0
0
50
396
1.27
0.86
1.7
1.7
9942.5
14559.6
e6/l
0.55
40
292
12
72
1.67
0.85
1.6
1.6
—
—
—
0
0
1906
19347
0.92
0.84
4.6
4.3
2.7
2.8
mmol/l
4.88
1786
18102
43
545
0.79
0.83
2.0
1.7
—
—
—
0
0
58
472
1.23
0.81
1.3
2.6
1.0
1.0
g/l
0.01
52
421
26
189
1.38
0.81
2.2
1.7
—
—
—
0
0
124
1415
0.87
0.80
1.8
1.9
—
—
—
0
0
31
233
1.33
0.79
1.1
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
20
140
1.43
0.77
3.2
2.3
—
—
—
0
0
137
1217
1.13
0.71
3.6
3.4
4.4
4.6
pmol/l
1.26
122
1091
147
1312
1.13
0.71
2.6
2.2
5.3
7.6
ug/l
1.14
137
1188
5
26
1.93
0.70
1.6
1.3
—
—
—
0
0
5
26
1.93
0.70
1.4
1.4
—
—
—
0
0
7
41
1.71
0.70
1.0
1.1
—
—
—
0
0
9
58
1.55
0.69
5.8
4.3
—
—
—
0
0
50
409
1.23
0.69
2.8
2.5
47.1
135.6
ug/min
2.38
33
263
9
59
1.53
0.68
1.3
1.2
—
—
—
0
0
5
28
1.79
0.66
1.6
1.2
—
—
—
0
0
7
44
1.59
0.65
1.0
1.1
—
—
—
0
0
13
89
1.46
0.58
1.2
1.1
153.7
184.7
iu/ml
0.29
13
89
35
283
1.24
0.56
1.3
1.4
7.4
7.2
mmol/l
0.13
28
205
1689
17138
0.95
0.55
6.2
5.0
39.9
39.0
mmol/mol
2.89
1589
16098
24
186
1.29
0.54
1.3
1.4
11.1
12.8
mmol/l
—
5
46
12
82
1.47
0.54
1.3
1.1
—
—
—
0
0
9
60
1.50
0.54
1.3
1.1
—
—
—
0
0
6
39
1.54
0.53
1.2
1.1
—
—
—
0
0
20
152
1.32
0.52
1.2
1.3
45696.0
87665.7
e6/l
0.40
11
103
6
40
1.50
0.51
1.2
1.3
—
—
—
0
0
6
40
1.50
0.51
1.5
1.5
—
—
—
0
0
9
135
0.67
0.51
1.6
1.9
—
—
—
0
0
43
510
0.84
0.51
2.4
2.0
3.7
4.7
iu/l
0.50
23
190
40
476
0.84
0.49
1.4
1.5
—
—
—
0
0
464
4847
0.95
0.49
1.9
1.6
1.5
1.4
mmol/l
0.45
399
4156
1879
18988
0.95
0.48
4.3
4.0
1.4
1.4
mmol/l
0.38
1763
17804
5
85
0.59
0.45
1.4
1.1
—
—
—
0
0
11
78
1.41
0.43
1.0
1.0
—
—
—
0
0
17
218
0.78
0.42
1.2
1.0
—
—
—
0
0
5
32
1.56
0.42
1.0
1.3
—
—
—
0
0
8
57
1.40
0.42
1.4
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
69
772
0.89
0.40
1.9
1.8
38.5
38.3
nmol/l
0.02
69
751
24
196
1.23
0.39
1.2
1.4
100.2
75.4
pmol/l
—
10
62
11
148
0.74
0.38
1.2
1.1
—
—
—
0
0
21
258
0.81
0.38
5.2
3.7
17.3
29.7
u/ml
1.40
21
253
549
5667
0.96
0.37
4.6
4.3
3.9
2.2
ug/l
0.56
504
5109
11
146
0.75
0.36
1.2
1.1
—
—
—
0
0
11
146
0.75
0.36
1.2
1.1
—
—
—
0
0
11
146
0.75
0.36
1.2
1.1
—
—
—
0
0
11
146
0.75
0.36
1.1
1.7
—
—
—
0
0
13
99
1.31
0.35
2.4
1.8
—
—
—
0
0
1815
18315
0.96
0.35
4.0
3.6
1.3
1.3
mmol/l
0.69
1702
17107
37
320
1.16
0.34
1.0
1.1
—
—
—
0
0
23
191
1.21
0.33
1.5
1.6
7.1
7.5
mmol/l
0.46
15
118
11
144
0.76
0.33
1.2
1.1
—
—
—
0
0
11
144
0.76
0.33
1.2
1.1
—
—
—
0
0
25
296
0.84
0.33
1.3
1.2
—
—
—
0
0
14
112
1.25
0.28
1.4
2.1
—
—
—
0
0
42
377
1.12
0.25
1.1
1.1
1.2
3.6
u/ml
2.18
11
151
48
435
1.11
0.25
1.2
2.4
38.9
38.1
g/l
0.43
42
380
13
105
1.24
0.24
1.2
1.1
—
—
—
0
0
310
3200
0.96
0.23
1.9
2.1
—
—
—
0
0
18
153
1.18
0.22
2.9
4.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
1.7
—
0
11
13
156
0.83
0.21
1.1
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
14
117
1.20
0.20
1.1
1.2
—
—
—
0
0
66
707
0.93
0.20
1.4
1.5
—
—
—
0
0
11
90
1.22
0.19
1.3
1.7
—
—
—
0
0
11
90
1.22
0.19
1.3
1.7
—
—
—
0
0
280
2879
0.97
0.18
1.8
2.0
—
—
—
0
0
29
321
0.90
0.18
1.1
1.6
—
—
—
0
0
7
62
1.13
0.17
1.0
1.0
—
—
—
0
0
8
68
1.18
0.16
1.0
1.1
—
—
—
0
0
152
1465
1.04
0.16
1.2
1.2
102.6
141.0
iu/ml
0.64
61
559
22
246
0.89
0.16
1.2
1.1
—
—
—
0
0
8
71
1.13
0.16
1.6
1.1
—
—
—
0
0
15
130
1.15
0.15
1.7
1.3
—
—
—
0
0
14
161
0.87
0.15
1.1
1.1
—
—
—
0
0
14
159
0.88
0.13
1.4
1.5
—
—
—
0
0
36
335
1.08
0.13
1.4
1.3
—
—
—
0
0
36
335
1.08
0.13
1.4
1.3
—
—
—
0
0
1903
19091
0.98
0.11
4.4
4.0
4.6
4.7
mmol/l
2.86
1794
17992
36
339
1.06
0.10
1.1
1.1
—
—
—
0
0
208
2042
1.02
0.09
8.3
6.0
—
—
—
0
0
6
55
1.09
0.09
1.0
1.9
—
—
—
0
0
46
439
1.05
0.09
1.2
1.2
—
—
—
0
0
36
341
1.06
0.08
1.2
1.2
7.5
3.6
u/ml
0.56
21
115
20
186
1.08
0.07
1.2
1.2
35.3
43.8
mg/l
0.51
15
153
112
1097
1.02
0.06
1.0
1.1
—
—
—
0
0
30
287
1.05
0.05
1.3
1.2
—
—
—
0
0
170
1722
0.99
0.05
2.5
2.2
12.6
13.2
nmol/l
0.46
156
1562
69
704
0.98
0.04
1.9
1.8
—
—
—
0
0
20
210
0.95
0.03
1.2
1.1
—
—
—
0
0
39
379
1.03
0.03
1.3
1.5
0.4
0.4
nmol/l
0.11
33
301
18
189
0.95
0.03
4.7
4.9
12.6
91.6
u/ml
—
8
55
34
350
0.97
0.03
1.1
1.1
2.5
5.1
u/ml
1.16
12
146
17
178
0.95
0.02
1.2
1.1
—
—
—
0
0
34
332
1.02
0.01
1.2
1.3
6.2
5.1
u/ml
0.23
21
152
49
498
0.98
0.01
1.2
1.1
2.0
1.5
u/ml
0.09
11
208
46
453
1.02
0.01
1.6
1.4
53.4
23.1
e6/l
0.38
39
354
61
609
1.00
0.00
1.4
1.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
12
116
1.03
0.00
1.4
1.1
—
—
—
0
0
1827
18266
1.00
0.00
4.2
4.0
5.9
5.9
mmol/l
0.68
1695
16915
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
1500.8
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint ULCEROTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ULCEROTH | 1.372 [1.22, 1.55] | < 0.001 |
| Birth year | 1.001 [0.99, 1.01] | 0.903 |
During the follow-up period (1.1.1998 — 31.12.2019), 567 out of 5349 females with ULCEROTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ULCEROTH | 1.247 [1.12, 1.39] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.025 |
During the follow-up period (1.1.1998 — 31.12.2019), 815 out of 5965 males with ULCEROTH died.
Mortality risk
Mortality risk for people of age
years, who have ULCEROTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.097% | 0.224% |
| 5 | 0.749% | 1.434% |
| 10 | 2.112% | 3.919% |
| 15 | 4.287% | 7.111% |
| 20 | 7.497% | 12.132% |
Relationships between endpoints
↥Index endpoint: ULCEROTH – Other ulcerative colitis
GWS hits: 12
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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