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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart CD2_INSITU_OTHER_NOS_EXALLC for full statistics.

Carcinoma in situ of other and unspecified sites

CD2_INSITU_OTHER_NOS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D09
  • Cause of death: ICD-10 D09

2 out of 7 registries used, show all original rules.

135

4. Check minimum number of events

None

135

5. Include endpoints

1176

6. Filter based on genotype QC (FinnGen only)

1176

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D00-D09
Name in latin
Carcinoma in situ locis aliis sive non specificatis

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1176 236 940
Unadjusted period prevalence (%) 0.35 0.08 0.41
Median age at first event (years) 71.36 68.13 72.17

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1088
Matched controls
10879
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UKC02
NOMESCO Finland
Cystoscopy
87.8
323.0
1023
1653
KCD02
NOMESCO Finland
Transurethral resection of bladder
124.9
323.0
698
153
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
68.6
323.0
439
106
D41.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bladder
120.7
323.0
589
105
KCD05
NOMESCO Finland
Excision of bladder lesion during urinary tract endoscopy with photodynamic diagnosis (PDD)
176.8
323.0
500
52
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
150.8
323.0
672
115
8130/2-C67.9
ICD-O-3
Papillary urothelial carcinoma, non-invasive of bladder, NOS
16384.0
323.0
711
*
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
71.0
274.4
311
61
UKC05
NOMESCO Finland
Cystoscopy and bladder biopsy
73.9
270.9
305
57
R31
ICD-10 Finland
Unspecified haematuria
11.6
256.7
579
973
ZX136
NOMESCO Finland
Intravesicalis
56.9
153.3
181
38
8120/2-C67.9
ICD-O-3
Urothelial carcinoma in situ of bladder, NOS
1511.7
139.7
133
*
KCD32
NOMESCO Finland
Cystoscopic destruction of tumour of bladder
40.9
139.7
176
51
KH1CD
NOMESCO Finland
Very extensive urinary tract ultrasound examination
27.6
110.1
153
64
WX320
NOMESCO Finland
Spinalanesthesy
4.6
106.9
493
1661
D09.0
ICD-10 Finland
Carcinoma in situ: Bladder
+∞
87.7
83
*
8130/2-C67.2
ICD-O-3
Papillary urothelial carcinoma, non-invasive of lateral wall of bladder
837.4
80.5
78
*
XKD00
NOMESCO Finland
Uroflowmetry
3.3
67.3
468
2027
TKC20
NOMESCO Finland
Catheterisation of bladder
5.0
62.9
225
538
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
3.4
62.8
386
1505
WC305
NOMESCO Finland
Simple therapy of local tumor recidive with biomodifiers
100.3
60.6
66
7
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
5.3
59.4
200
445
KCW96
NOMESCO Finland
Other operations on bladder
27.4
57.3
79
31
U06
ICPC
Haematuria
9.5
57.0
122
143
TKW99
NOMESCO Finland
Other minor surgical procedure in urology
18.9
55.5
86
49
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
50.1
432
2058
KH1BD
NOMESCO Finland
Extensive urinary tract CT examination
15.1
49.7
84
60
C67
ICD-10 Finland
Malignant neoplasm of bladder
60.0
48.9
57
10
WX224
NOMESCO Finland
Blockade of obturius nerve
156.2
43.1
45
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
8.7
39.1
87
108
WC105
NOMESCO Finland
Simple cytostatic therapy of local tumor recidive
44.5
38.4
47
11
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.2
37.4
228
836
WX402
NOMESCO Finland
General anaesthesia
3.1
36.4
236
903
KH1AD
NOMESCO Finland
CT of urinary organs
6.2
35.6
100
175
N30.0
ICD-10 Finland
Acute cystitis
3.4
34.9
186
617
C67.0
ICD-10 Finland
Malignant neoplasm: Trigone of bladder
26.3
34.8
48
19
J01MA02
ATC
ciprofloxacin; systemic
2.2
34.2
548
3411
UKB02
NOMESCO Finland
Retrograde ureteroscopy
10.2
34.2
69
72
4CX01
NOMESCO Finland
NA
124.0
33.9
36
*
KCW02
NOMESCO Finland
Lavation of bladder for coagulated blood
9.6
31.0
64
70
KBJ10
NOMESCO Finland
Cutaneous ureteroenterostomy
18.1
30.3
47
27
ZXC20
NOMESCO Finland
Use of chemical agents
6.8
29.7
77
121
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
6.9
29.4
75
115
KCB00
NOMESCO Finland
Biopsy of bladder
28.8
29.0
39
14
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.4
26.4
260
1249
G04BD12
ATC
mirabegron; oral
2.9
25.9
178
694
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.6
25.7
209
904
KCC10
NOMESCO Finland
Cystoprostatectomy
15.7
25.2
41
27
C67.4
ICD-10 Finland
Malignant neoplasm: Posterior wall of bladder
32.9
24.7
32
10
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
6.8
23.9
61
94
8130/2-C67.6
ICD-O-3
Papillary urothelial carcinoma, non-invasive of ureteric orifice
+∞
23.0
22
*
U76
ICPC
Malignant neoplasm of bladder
33.0
22.5
29
9
R33
ICD-10 Finland
Retention of urine
2.6
22.5
184
794
D41.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Renal pelvis
18.4
22.3
34
19
KH1DD
NOMESCO Finland
CT urography of urinary organs
81.8
21.7
24
*
ZXC15
NOMESCO Finland
Use of photodynamic technique
6.8
21.5
55
85
KED22
NOMESCO Finland
Transurethral resection of prostate
2.6
21.0
168
714
C67.1
ICD-10 Finland
Malignant neoplasm: Dome of bladder
24.8
20.9
29
12
C66
ICD-10 Finland
Malignant neoplasm of ureter
19.2
20.0
30
16
C67.5
ICD-10 Finland
Malignant neoplasm: Bladder neck
+∞
19.8
19
*
KDV10
NOMESCO Finland
Internal urethrotomy
6.0
18.5
51
88
G04CA02
ATC
tamsulosin; oral
1.8
18.3
470
3235
PJD54
NOMESCO Finland
Block dissection of iliac lymph nodes
11.3
18.3
34
31
A98
ICPC
Health maint/preventive medicine
2.3
16.9
990
8841
8130/2-C67.4
ICD-O-3
Papillary urothelial carcinoma, non-invasive of posterior wall of bladder
+∞
16.7
16
*
R82.8
ICD-10 Finland
Abnormal findings on cytological and histological examination of urine
23.5
16.5
23
10
J01EA01
ATC
trimethoprim; systemic
2.0
16.1
241
1361
JN4AD
NOMESCO Finland
Body CT examination
2.5
15.9
136
595
N02BE01
ATC
paracetamol; systemic, rectal
1.9
15.6
911
7909
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.3
15.5
58
141
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
6.0
15.1
41
70
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
4.4
14.9
54
128
KCD30
NOMESCO Finland
Destruction of tumour of bladder
57.5
14.8
17
*
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
7.0
14.8
36
53
D09.1
ICD-10 Finland
Carcinoma in situ: Other and unspecified urinary organs
+∞
14.6
14
*
D09.9
ICD-10 Finland
Carcinoma in situ, unspecified
+∞
14.6
14
*
UKA02
NOMESCO Finland
Retrograde ureteronephroscopy
12.2
14.1
25
21
KDV12
NOMESCO Finland
Urethroscopic internal urethrotomy
6.1
13.9
37
62
J01MA12
ATC
levofloxacin; systemic
1.8
13.5
258
1581
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.7
13.3
345
2325
C67.3
ICD-10 Finland
Malignant neoplasm: Anterior wall of bladder
50.6
12.9
15
*
8120/2-C67.2
ICD-O-3
Urothelial carcinoma in situ of lateral wall of bladder
+∞
12.5
12
*
B02AA02
ATC
tranexamic acid; systemic
2.3
12.2
116
537
C65
ICD-10 Finland
Malignant neoplasm of renal pelvis
16.1
12.2
19
12
D09.3
ICD-10 Finland
Carcinoma in situ: Thyroid and other endocrine glands
+∞
11.5
11
*
WZC30
NOMESCO Finland
Teaching
1.9
11.0
167
937
J01DB01
ATC
cefalexin; oral
1.6
11.0
824
7151
JN3AD
NOMESCO Finland
Abdominal CT examination
2.2
11.0
110
521
KCV22
NOMESCO Finland
Transluminal endoscopic evacuation of blood clots from bladder
21.7
10.7
15
7
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
10.7
527
4126
G04CA01
ATC
alfuzosin; oral
1.7
10.3
221
1391
R39.1
ICD-10 Finland
Other difficulties with micturition
3.0
10.3
59
205
SPAT1263
SPAT
Sampling
1.5
10.2
446
3381
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
3.8
10.1
41
110
SPAT1167
SPAT
Insertion of urinary catheter
2.7
10.0
70
273
KBH20
NOMESCO Finland
Replantation of ureter
16.9
9.9
15
9
KC1GB
NOMESCO Finland
Cystography with X-ray
4.7
9.7
32
70
SPAT1312
SPAT
General health counselling
1.6
9.6
313
2203
D41.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Ureter
17.7
9.4
14
8
JN4CD
NOMESCO Finland
Very extensive body CT
2.6
9.4
67
267
8130/2-C67.8
ICD-O-3
Papillary urothelial carcinoma, non-invasive of overlapping lesion of bladder
+∞
9.4
9
*
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
8.1
9.4
20
25
KBV10
NOMESCO Finland
Removal of stent from ureter
7.0
9.3
22
32
U07
ICPC
Urine symptom/complaint other
2.4
9.3
76
327
G04BD08
ATC
solifenacin; oral
2.2
9.1
88
412
N30.9
ICD-10 Finland
Cystitis, unspecified
2.7
9.1
62
242
C67.6
ICD-10 Finland
Malignant neoplasm: Ureteric orifice
37.0
9.0
11
*
KAC21
NOMESCO Finland
Percutaneous endoscopic nephroureterectomy
18.8
8.9
13
7
KH1FT
NOMESCO Finland
Exchange of urinary catheter with radiological guidance
8.0
8.9
19
24
U29
ICPC
Urinary symptom/complaint other
3.3
8.7
42
130
JN4BD
NOMESCO Finland
Extensive body CT
1.8
8.7
150
875
A02BC02
ATC
pantoprazole; systemic
1.5
8.5
661
5586
SPAT1262
SPAT
Handing over of treatment supplies
1.6
8.4
243
1654
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.5
8.3
66
278
Z71.8
ICD-10 Finland
Other specified counselling
1.7
8.2
195
1258
D30.3
ICD-10 Finland
Benign neoplasm: Bladder
14.6
8.2
13
9
U05
ICPC
Urination problems other
2.4
8.2
68
293
KBD00
NOMESCO Finland
Partial excision of ureter
17.3
8.1
12
7
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
1.7
8.0
162
997
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
7.9
137
803
R93.4
ICD-10 Finland
Abnormal findings on diagnostic imaging of urinary organs
7.8
7.9
17
22
TKC22
NOMESCO Finland
Catheterisation instruction
3.1
7.9
42
141
C61
ICD-10 Finland
Malignant neoplasm of prostate
1.6
7.8
194
1268
KA3EB
NOMESCO Finland
Antegrade pyelography
7.0
7.8
18
26
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.2
7.6
77
366
KBV00
NOMESCO Finland
Insertion of stent into ureter
7.2
7.5
17
24
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.2
7.4
72
340
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.7
7.3
48
184
Z08.2
ICD-10 Finland
Follow-up examination after chemotherapy for malignant neoplasm
30.2
7.2
9
*
U01
ICPC
Dysuria/painful urination
2.4
7.1
56
238
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
7.1
141
865
S18
ICPC
Laceration/cut
1.4
7.0
446
3574
J01CA08
ATC
pivmecillinam; oral
1.6
6.9
206
1408
KDE20
NOMESCO Finland
Removal of foreign body from urethra
4.2
6.8
24
58
N35.9
ICD-10 Finland
Urethral stricture, unspecified
3.9
6.8
26
68
D09.7
ICD-10 Finland
Carcinoma in situ of other specified sites
40.3
6.8
8
*
U02
ICPC
Urinary frequency/urgency
1.8
6.7
107
608
N21.0
ICD-10 Finland
Calculus in bladder
4.0
6.7
25
64
WX110
NOMESCO Finland
Local anesthesy
1.4
6.7
620
5296
KA1FN
NOMESCO Finland
Isotope renography
5.5
6.6
18
33
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.3
6.6
58
259
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
1.6
6.6
180
1205
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.3
6.4
57
257
KCE02
NOMESCO Finland
Transluminal endoscopic extraction of calculus from bladder
4.4
6.4
21
48
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
6.3
450
3659
8130/2-C67.5
ICD-O-3
Papillary urothelial carcinoma, non-invasive of bladder neck
+∞
6.3
6
*
B01AB10
ATC
tinzaparin; parenteral
2.0
6.2
79
416
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
6.2
195
1347
B01AB05
ATC
enoxaparin; parenteral
1.4
6.0
319
2452
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
6.0
187
1288
N40
ICD-10 Finland
Hyperplasia of prostate
1.4
6.0
392
3131

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_OTHER_NOS – Carcinoma in situ of other and unspecified sites

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).