Helminthiases

AB1_HELMINTIASES

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B65-B83
  • Hospital discharge: ICD-9 12[0-3]
  • Hospital discharge: ICD-8 12[0-9]|13602
  • Cause of death: ICD-10 B65-B83
  • Cause of death: ICD-9 12[0-3]
  • Cause of death: ICD-8 12[0-9]|13602

2 out of 7 registries used, show all original rules.

621

4. Check minimum number of events

None

621

5. Include endpoints

663

6. Filter based on genotype QC (FinnGen only)

628

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF6V3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8913 4944 3842
Only index persons 5959 3558 2401
Unadjusted period prevalence (%)
Whole population 0.13 0.14 0.11
Only index persons 0.12 0.13 0.09
Median age at first event (years)
Whole population 33.97 31.17 37.09
Only index persons 29.01 28.92 29.15

-FinnGen-

Key figures

All Female Male
Number of individuals 628 383 245
Unadjusted period prevalence (%) 0.13 0.14 0.11
Median age at first event (years) 36.59 33.66 41.19

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
662
Matched controls
6620
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B80
ICD-10 Finland
Enterobiasis
262.2
145.4
144
7
12340
ICD-8 Finland
Other cestode infection, Diphyllobothriasis, intestinal
+∞
127.3
118
*
12730
ICD-8 Finland
Other intestinal helminthiasis, Enterobiasis
+∞
32.6
31
*
1252A
ICD-9 Finland
Filarial infection and dracontiasis, Loiasis
+∞
24.1
23
*
B76.9
ICD-10 Finland
Hookworm disease, unspecified
+∞
18.8
18
*
B83.9
ICD-10 Finland
Helminthiasis, unspecified
92.4
16.6
18
*
B82.9
ICD-10 Finland
Intestinal parasitism, unspecified
+∞
13.6
13
*
12700
ICD-8 Finland
Other intestinal helminthiasis, Ascariasis
+∞
12.5
12
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.6
11.6
73
305
B70.0
ICD-10 Finland
Diphyllobothriasis
+∞
11.5
11
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
10.6
99
492
B83.8
ICD-10 Finland
Other specified helminthiases
+∞
9.4
9
*
UJF30
NOMESCO Finland
Ileoscopy through colon
2.3
9.0
70
322
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
4.6
8.9
21
47
B65.3
ICD-10 Finland
Cercarial dermatitis
50.7
8.7
10
*
12899
ICD-8 Finland
Other and unspecified helminthiasis, Unspecified
+∞
8.3
8
*
N02AX02
ATC
tramadol; systemic, rectal
1.6
8.3
264
1914
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
4.7
7.9
18
39
D01
ICPC
Abdominal pain/cramps general
2.0
7.7
87
465
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
7.6
180
1205
12699
ICD-8 Finland
Ankylostomiasis, Unspecified
+∞
7.3
7
*
B82.0
ICD-10 Finland
Intestinal helminthiasis, unspecified
+∞
7.3
7
*
B78.9
ICD-10 Finland
Strongyloidiasis, unspecified
+∞
7.3
7
*
B65.9
ICD-10 Finland
Schistosomiasis, unspecified
+∞
7.3
7
*
12720
ICD-8 Finland
Other intestinal helminthiasis, Trichuriasis
+∞
7.3
7
*
1234A
ICD-9 Finland
Other cestode infection, Diphyllobothriasis, intestinal
+∞
7.3
7
*
12740
ICD-8 Finland
Other intestinal helminthiasis, Other intestinal nematode infection
+∞
7.3
7
*
12299
ICD-8 Finland
Hydatidosis, Of unspecified site
+∞
7.3
7
*
A02BC01
ATC
omeprazole; systemic
1.7
7.2
175
1177
L04AX01
ATC
azathioprine; systemic
2.9
6.7
31
111
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
6.3
232
1714
1274A
ICD-9 Finland
Other intestinal helminthiases, Enterobiasis
+∞
6.3
6
*
N77.1*B80
ICD-10 Finland
Vaginitis, vulvitis and vulvovaginitis in pinworm infection
+∞
6.3
6
*
B77.9
ICD-10 Finland
Ascariasis, unspecified
+∞
6.3
6
*
12320
ICD-8 Finland
Other cestode infection, Taenia saginata infection
+∞
6.3
6
*
B81.4
ICD-10 Finland
Mixed intestinal helminthiases
+∞
6.3
6
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.4
6.2
40
170

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
326
2470
1.63
8.64
9.6
6.4
—
—
—
0
0
327
2498
1.61
8.25
9.4
5.8
3.15
2.88
%
1.00
304
2341
317
2416
1.60
7.99
9.5
5.9
0.72
0.68
%
0.72
292
2255
34
116
3.04
7.92
1.5
1.4
171.20
235.64
u/ml
1.11
22
65
326
2509
1.59
7.83
9.8
6.1
8.72
8.46
%
0.65
303
2357
330
2554
1.58
7.70
9.1
5.7
55.30
56.71
%
1.35
308
2407
332
2584
1.57
7.48
9.6
5.9
28.90
28.68
%
0.13
310
2433
338
2648
1.56
7.36
7.9
5.8
11.03
11.26
umol/l
0.19
320
2498
466
3954
1.60
6.97
10.4
7.0
80.57
79.24
u/l
0.22
448
3704
345
2738
1.54
6.93
9.5
6.1
0.21
0.19
e9/l
0.60
307
2419
189
1316
1.61
6.71
9.3
6.5
—
—
—
0
0
184
1274
1.62
6.68
5.8
3.8
91.11
91.38
%
0.05
178
1249
333
2638
1.53
6.65
9.1
5.7
0.56
0.57
e9/l
0.30
297
2292
233
1707
1.56
6.64
3.8
3.1
32.99
30.61
u/l
0.40
222
1625
86
481
1.91
6.62
2.5
2.6
36.45
33.55
u/l
0.14
75
395
333
2648
1.52
6.47
9.1
5.7
0.04
0.04
e9/l
0.52
296
2301
16
39
4.18
6.12
1.3
2.2
—
—
—
0
0
27
97
2.86
5.79
1.7
1.4
116.00
107.11
u/ml
—
5
16
337
2730
1.48
5.72
9.2
5.7
2.02
1.96
e9/l
0.09
306
2441
73
406
1.90
5.72
2.8
2.7
11.11
10.13
g/l
0.99
67
373
93
561
1.77
5.61
3.5
2.8
1.79
1.81
%
0.05
80
503
28
109
2.64
5.20
1.7
1.5
—
—
—
0
0
159
1121
1.55
5.19
2.2
2.0
—
—
—
0
0
44
212
2.15
5.12
1.5
1.4
—
—
—
0
0
69
393
1.84
5.03
3.4
2.7
67.22
71.58
e9/l
0.50
54
307
197
1486
1.46
4.59
5.7
3.7
7.40
7.40
ph
0.01
32
280
364
3069
1.41
4.57
12.4
8.7
3.81
4.04
e9/l
1.32
326
2675
281
2268
1.42
4.51
8.1
5.9
1.21
1.22
mmol/l
0.03
268
2078
94
608
1.64
4.38
1.9
1.6
—
—
—
0
0
93
600
1.64
4.38
4.5
2.8
6.42
7.66
umol/l
0.47
78
507
291
2372
1.40
4.38
11.9
9.1
0.00
0.00
e9/l
0.72
245
1943
101
666
1.61
4.36
3.6
2.3
22.55
22.77
%
0.06
89
580
237
1867
1.42
4.32
4.4
3.8
50.54
114.89
e6/l
1.35
167
1302
172
1280
1.46
4.25
2.8
2.1
2.84
3.02
mg/l
0.53
147
1091
277
2250
1.40
4.21
14.7
13.2
1.25
1.21
inr
0.24
75
683
184
1398
1.44
4.06
3.6
3.2
—
—
—
0
0
118
824
1.53
3.96
3.1
3.1
2.32
2.62
e6/l
0.21
65
453
156
1154
1.46
3.95
1.8
1.4
2.16
2.35
g/l
0.52
90
689
15
48
3.17
3.95
1.4
2.4
—
—
—
0
0
45
242
1.92
3.94
1.2
1.5
25.50
24.94
iu/l
0.04
31
200
262
2131
1.38
3.87
2.7
2.3
79.18
75.39
nmol/l
1.52
242
1910
202
1574
1.41
3.84
3.8
3.3
68.48
110.08
e6/l
0.38
159
1210
85
555
1.61
3.82
1.4
1.3
—
—
—
0
0
57
335
1.77
3.78
2.0
1.6
1.14
1.52
g/l
0.96
51
310
100
682
1.55
3.74
2.4
2.3
112.73
114.25
ug/g
0.02
80
540
260
2123
1.37
3.71
7.5
4.7
35.34
35.87
g/l
0.86
246
1988
185
1431
1.41
3.65
3.7
3.3
0.17
0.42
e6/l
2.86
140
1082
126
911
1.47
3.57
1.7
1.7
1153.88
1181.34
nmol/l
0.12
104
689
286
2382
1.35
3.55
3.8
2.7
108.25
107.27
ug/l
0.03
265
2185
161
1221
1.42
3.54
3.8
3.5
—
—
—
0
0
399
3497
1.35
3.53
5.2
4.4
223.20
2175.24
e6/l
—
5
59
74
477
1.62
3.51
3.2
2.3
0.19
0.22
g/l
2.96
68
450
8
13
6.21
3.51
3.9
3.8
—
—
—
0
0
102
709
1.52
3.50
3.5
2.3
2.42
2.36
g/l
0.50
96
657
240
1950
1.36
3.48
2.2
1.9
92.37
93.88
pmol/l
0.19
123
982
173
1340
1.39
3.35
5.3
3.9
—
—
—
0
0
125
914
1.45
3.34
1.9
1.7
—
—
—
0
0
59
364
1.68
3.32
2.5
2.4
47.66
19.52
au/ml
—
5
21
94
650
1.52
3.30
1.8
1.5
—
—
—
0
0
71
461
1.61
3.28
1.2
1.2
—
—
—
0
0
61
382
1.66
3.25
5.4
3.9
98.09
75.71
ng/l
0.90
55
348
34
179
1.95
3.20
10.2
9.1
—
—
—
0
0
8
15
5.38
3.20
1.1
1.1
—
—
—
0
0
294
2490
1.33
3.15
9.7
6.5
1.22
1.21
mmol/l
0.23
256
2135
38
209
1.87
3.15
1.2
1.2
—
—
—
0
0
9
20
4.55
3.12
3.2
3.0
462.89
726.55
u/ml
—
9
20
345
2992
1.32
3.12
6.4
4.6
6.56
6.59
mmol/l
0.12
327
2766
409
3635
1.33
3.10
5.0
4.3
—
—
—
0
0
431
3863
1.33
3.06
4.9
4.0
11.76
11.56
mm/h
0.10
404
3546
16
63
2.58
2.97
1.5
1.3
—
—
—
0
0
28
142
2.01
2.94
1.4
1.4
294.61
291.37
ug/g
0.02
18
81
13
47
2.80
2.83
1.0
1.2
—
—
—
0
0
48
294
1.68
2.80
1.3
1.3
—
—
—
0
0
146
1141
1.36
2.63
2.8
1.8
1.25
1.15
mg/l
0.17
104
874
7
15
4.70
2.60
1.7
1.7
—
—
—
0
0
84
599
1.46
2.56
1.7
1.3
—
—
—
0
0
19
88
2.19
2.53
1.1
1.1
—
—
—
0
0
138
1077
1.36
2.51
3.0
2.6
3.90
6.26
e6/l
1.52
125
962
16
69
2.35
2.50
3.1
2.6
—
—
—
0
0
9
26
3.49
2.49
1.7
1.6
—
—
—
0
0
17
77
2.24
2.39
1.1
1.1
—
—
—
0
0
133
1046
1.34
2.29
3.2
3.0
558.65
543.54
mosm/kgh2o
0.31
121
893
7
18
3.92
2.25
1.4
1.1
—
—
—
0
0
119
923
1.35
2.25
4.0
3.6
413.25
316.42
ng/l
0.13
80
685
19
93
2.07
2.23
1.3
1.8
—
—
—
0
0
21
107
1.99
2.22
1.2
1.3
—
—
—
0
0
10
35
2.88
2.21
1.8
1.4
—
—
—
0
0
151
1841
0.77
2.17
2.9
2.8
—
—
—
0
0
14
61
2.32
2.16
1.1
1.2
—
—
—
0
0
7
19
3.71
2.15
1.0
1.0
—
—
—
0
0
195
1633
1.28
2.11
3.0
3.0
—
—
—
0
0
21
110
1.94
2.07
1.2
1.7
3.39
3.80
mmol/l
0.92
21
103
6
15
4.03
2.04
3.2
1.3
—
—
—
0
0
195
1640
1.27
2.03
3.5
2.3
—
—
—
0
0
23
126
1.86
2.00
1.3
1.7
674.61
426.85
mg/l
1.40
23
119
26
149
1.78
1.97
1.4
1.8
38.69
40.52
nmol/l
0.21
26
144
383
3481
1.24
1.97
3.9
3.6
—
—
—
0
0
19
98
1.97
1.97
1.1
1.1
1.06
5.26
u/ml
—
8
54
19
98
1.97
1.97
2.2
2.3
129.69
127.55
g/l
0.15
13
71
7
21
3.36
1.97
2.1
1.6
35.70
63.34
ug/l
—
7
21
188
1580
1.27
1.96
3.4
2.5
64.86
60.69
u/l
0.15
173
1460
234
2018
1.25
1.95
2.2
2.1
—
—
—
0
0
10
39
2.59
1.94
1.3
2.7
36.52
40.89
%
—
10
39
59
416
1.46
1.94
1.6
1.4
—
—
—
0
0
8
27
2.99
1.94
1.3
1.2
—
—
—
0
0
19
99
1.95
1.92
1.4
2.5
4.82
9.71
umol/l
0.81
13
71
474
5035
0.79
1.91
4.5
4.1
1.45
1.47
mmol/l
0.47
439
4656
156
1286
1.28
1.90
1.6
1.3
1.49
1.73
u/ml
0.12
29
332
29
174
1.70
1.89
1.2
1.2
—
—
—
0
0
29
174
1.70
1.89
1.2
1.6
11.87
9.63
u/l
0.36
24
141
477
5056
0.80
1.82
4.6
4.2
4.60
4.66
mmol/l
0.54
448
4697
5
12
4.19
1.82
1.4
1.2
—
—
—
0
0
84
639
1.36
1.81
1.8
1.7
—
—
—
0
0
37
241
1.57
1.77
2.9
2.3
154.06
3009.20
u/l
1.79
18
98
28
170
1.68
1.76
2.1
3.1
—
—
—
0
0
94
731
1.33
1.76
1.4
1.3
392.73
444.90
titre
0.26
22
155
15
74
2.05
1.76
1.3
1.5
—
—
—
0
0
7
24
2.94
1.72
1.6
1.8
—
—
—
0
0
457
4856
0.81
1.72
4.0
3.8
1.29
1.27
mmol/l
0.24
424
4471
20
111
1.83
1.70
1.3
1.2
0.26
3.32
u/ml
—
10
64
61
446
1.41
1.68
7.4
8.3
—
—
—
0
0
6
19
3.18
1.66
1.7
1.5
143.50
149.84
nmol/l
—
6
19
8
31
2.60
1.66
1.4
1.3
1.52
1.54
g/l
—
8
31
89
693
1.33
1.66
1.2
1.2
—
—
—
0
0
7
25
2.82
1.65
1.3
1.4
—
—
—
0
0
33
214
1.57
1.63
1.4
1.7
—
—
—
0
0
12
56
2.16
1.62
3.5
2.6
18.55
21.10
nmol/l
0.45
12
51
242
2131
1.21
1.60
3.8
3.4
6.50
5.93
ph
1.49
11
178
8
32
2.52
1.60
7.5
2.7
—
—
—
0
0
179
1532
1.23
1.56
3.6
3.4
7.83
7.68
mmol/l
0.13
156
1296
10
44
2.29
1.56
6.5
2.5
—
—
—
0
0
8
33
2.44
1.54
1.3
1.2
1.96
1.80
mmol/l
—
8
33
217
1897
1.21
1.54
3.4
3.6
30.93
39.53
ng/l
0.52
147
1284
159
1346
1.24
1.54
3.7
3.3
796.30
257.49
mg/l
0.49
107
870
126
1039
1.26
1.53
1.6
1.7
56000460.31
20785658.25
pmol/l
0.27
100
866
17
93
1.85
1.53
1.2
1.1
1.80
2.14
u/ml
—
9
52
17
93
1.85
1.53
1.1
1.1
0.67
0.58
u/ml
—
7
45
7
27
2.61
1.52
1.1
1.2
—
—
—
0
0
11
51
2.18
1.51
1.0
1.1
—
—
—
0
0
48
344
1.43
1.49
1.4
1.2
—
—
—
0
0
17
94
1.83
1.48
2.2
3.5
—
—
—
0
0
9
37
2.45
1.48
2.0
1.4
0.95
0.97
g/l
—
9
37
36
244
1.50
1.48
2.4
2.4
—
—
—
0
0
553
5297
1.27
1.47
19.2
13.1
22.15
23.23
mg/l
0.36
454
4132
554
5310
1.27
1.45
20.3
15.1
139.55
139.62
mmol/l
0.30
544
5170
292
2640
1.19
1.42
4.1
3.7
0.02
0.00
estimate
0.49
47
488
555
5324
1.26
1.42
20.7
15.1
3.94
3.96
mmol/l
1.20
541
5172
30
199
1.53
1.37
1.1
1.4
158.70
260.55
miu/ml
—
10
87
6
23
2.62
1.37
1.2
1.3
—
—
—
0
0
6
23
2.62
1.37
1.7
1.5
—
—
—
0
0
148
1261
1.22
1.34
3.2
2.2
—
—
—
0
0
21
128
1.66
1.34
1.7
2.8
—
—
—
0
0
64
492
1.33
1.33
6.5
4.3
1.69
2.03
mmol/l
0.42
55
401
19
113
1.70
1.33
1.6
1.7
5539.31
18032.78
e6/l
1.34
13
86
492
5149
0.83
1.32
5.1
4.6
2.69
2.76
mmol/l
1.15
458
4750
92
744
1.27
1.32
2.2
1.9
—
—
—
0
0
164
1417
1.21
1.30
4.2
3.8
7.19
10.67
mg/mmol
0.67
104
890
46
338
1.39
1.27
4.2
4.0
7.42
7.41
ph
—
6
37
16
92
1.76
1.26
1.2
1.1
—
—
—
0
0
16
92
1.76
1.26
1.2
1.1
—
—
—
0
0
13
70
1.87
1.24
2.0
1.8
—
—
—
0
0
12
63
1.92
1.23
1.5
1.7
—
—
—
0
0
14
78
1.81
1.22
1.1
1.0
4.74
4.03
u/ml
—
8
36
23
148
1.57
1.21
1.3
1.3
—
—
—
0
0
23
148
1.57
1.21
5.3
2.7
—
—
—
0
0
76
609
1.28
1.19
1.4
1.5
—
—
—
0
0
286
2611
1.17
1.19
5.5
5.0
0.00
0.00
estimate
-0.00
50
504
5
20
2.51
1.15
2.4
3.7
—
—
—
0
0
285
2606
1.16
1.15
4.1
3.7
0.00
0.00
estimate
0.50
49
534
54
416
1.32
1.13
6.0
4.6
0.71
0.97
%
0.41
29
155
50
382
1.33
1.11
5.5
4.4
0.48
0.56
%
0.14
26
129
12
66
1.83
1.09
1.2
1.1
15.05
4.94
u/ml
—
5
23
504
4826
1.19
1.09
5.6
4.6
1.86
2.14
mu/l
0.59
474
4413
9
46
1.97
1.04
1.9
2.4
1.03
1.18
e9/l
—
9
38
9
46
1.97
1.04
1.1
1.2
—
—
—
0
0
5
22
2.28
1.03
1.0
1.2
111.24
187.84
iu/ml
—
5
22
9
47
1.93
1.02
1.2
1.1
—
—
—
0
0
145
1268
1.18
1.01
3.4
2.6
1858.34
7526.33
umol/l
2.04
128
1108
16
99
1.63
1.00
3.4
3.5
—
—
—
0
0
13
76
1.72
0.99
2.2
3.3
—
—
—
0
0
51
399
1.30
0.98
2.1
2.3
9.32
7.36
ug/l
0.25
41
351
5
23
2.18
0.98
4.4
2.8
37920.00
35591.52
ug/l
—
5
23
5
23
2.18
0.98
1.4
1.0
—
—
—
0
0
17
108
1.59
0.97
11.3
3.0
—
—
—
0
0
11
62
1.79
0.94
1.5
3.0
—
—
—
0
0
425
4041
1.14
0.92
4.8
3.8
14.76
14.71
pmol/l
0.18
394
3659
367
3458
1.14
0.90
3.9
3.1
47.19
46.19
u/l
0.08
348
3237
6
29
2.08
0.89
1.3
2.4
—
—
—
0
0
49
389
1.28
0.86
5.8
4.8
0.00
0.13
%
3.52
24
127
43
538
0.79
0.79
1.2
1.4
—
—
—
0
0
19
131
1.46
0.79
1.8
2.4
—
—
—
0
0
7
123
0.56
0.78
1.1
1.1
—
—
—
0
0
150
1344
1.15
0.78
4.8
4.6
1.78
2.45
ug/l
1.36
137
1207
6
34
1.77
0.76
2.5
2.3
0.13
0.17
e9/l
—
6
27
133
1183
1.16
0.76
4.4
3.8
1.02
1.02
kg/l
0.35
16
161
34
262
1.31
0.76
2.7
2.8
0.14
0.14
e6/l
0.01
34
254
22
158
1.41
0.75
5.2
7.0
1.23
1.42
mg/l
0.75
22
146
12
75
1.61
0.75
2.8
1.6
—
—
—
0
0
156
1406
1.14
0.74
4.2
3.9
0.00
0.01
estimate
0.69
47
498
5
26
1.93
0.70
1.4
1.0
—
—
—
0
0
7
41
1.71
0.70
22.1
3.4
10.67
10.89
%
—
7
41
12
77
1.57
0.69
1.3
1.3
—
—
—
0
0
53
439
1.23
0.68
5.7
3.7
4.74
4.51
kpa
0.35
53
426
7
42
1.67
0.68
1.0
1.1
86.86
35.59
mg/l
—
7
32
7
42
1.67
0.68
2.0
2.6
—
—
—
0
0
165
1503
1.13
0.67
2.4
2.1
204.84
248.04
u/l
0.30
155
1423
169
1543
1.13
0.67
1.7
1.5
—
—
—
0
0
10
62
1.62
0.65
6.6
4.5
—
—
—
0
0
31
243
1.29
0.64
11.1
10.0
—
—
—
0
0
12
79
1.53
0.63
1.6
1.6
—
—
—
0
0
12
79
1.53
0.63
1.2
1.1
—
—
—
0
0
568
5560
1.15
0.61
13.8
9.8
26.40
25.73
u/l
0.39
557
5354
89
784
1.16
0.60
2.9
2.9
0.65
0.78
ug/l
1.00
62
503
0
21
0.00
0.60
0.0
3.5
—
33.13
—
0
16
40
327
1.24
0.60
3.1
2.6
—
—
—
0
0
8
52
1.54
0.59
1.5
1.3
—
—
—
0
0
147
1342
1.12
0.58
1.7
1.6
1.36
1.38
mmol/l
0.13
128
1138
6
36
1.67
0.57
2.3
2.3
334.67
573.74
e6/l
—
6
27
5
86
0.58
0.56
1.4
3.0
—
—
—
0
0
48
404
1.20
0.55
4.9
3.2
—
—
—
0
0
30
240
1.26
0.54
9.3
10.1
23.70
24.56
mmol/l
1.12
30
234
482
4684
1.11
0.54
22.5
15.8
14.46
14.73
%
0.60
477
4617
13
91
1.44
0.53
1.1
1.1
—
12.89
—
0
7
473
4596
1.10
0.52
24.5
16.8
331.32
332.68
g/l
2.47
473
4562
9
63
1.43
0.52
1.2
1.2
—
—
—
0
0
9
63
1.43
0.52
3.4
2.6
—
—
—
0
0
125
1139
1.12
0.52
1.5
1.5
18.29
20.76
nmol/l
1.28
111
964
10
67
1.50
0.50
1.2
1.4
275.50
284.10
mosm/kgh2o
—
10
51
15
110
1.37
0.49
3.3
3.0
1.81
2.80
mmol/l
—
8
74
13
93
1.41
0.48
2.2
1.8
—
—
—
0
0
44
374
1.19
0.47
6.4
4.8
0.08
0.16
%
0.33
18
111
131
1421
0.90
0.47
3.7
3.7
—
—
—
0
0
258
2450
1.09
0.47
3.7
2.6
—
—
—
0
0
7
49
1.43
0.46
1.4
1.2
—
—
—
0
0
148
1374
1.10
0.44
3.7
3.1
1461.73
1394.66
ng/l
0.07
128
1164
16
121
1.33
0.44
1.4
1.2
—
—
—
0
0
6
94
0.64
0.42
7.7
3.4
13.00
25.53
u/ml
—
6
94
8
57
1.41
0.42
1.5
1.7
31.38
32.35
pg
—
8
57
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.6
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.8
—
—
—
0
0
36
309
1.17
0.37
3.1
2.2
—
—
—
0
0
5
37
1.35
0.37
1.2
1.5
176.08
158.80
pmol/l
—
5
37
137
1464
0.92
0.37
3.6
3.3
—
—
—
0
0
35
301
1.17
0.35
1.5
1.1
—
77.29
—
0
7
31
265
1.18
0.34
4.9
3.8
—
—
—
0
0
6
87
0.69
0.33
1.3
1.5
22.77
22.91
u/l
—
6
73
6
46
1.31
0.33
1.0
1.4
—
—
—
0
0
47
418
1.13
0.32
1.3
1.4
—
—
—
0
0
21
174
1.21
0.32
3.1
2.6
—
—
—
0
0
558
5512
1.08
0.27
16.0
12.4
—
—
—
0
0
22
187
1.18
0.27
4.4
4.8
—
—
—
0
0
489
4965
0.94
0.26
4.6
4.3
5.89
5.88
mmol/l
0.04
452
4526
19
161
1.19
0.24
1.6
1.5
—
—
—
0
0
586
5912
0.92
0.24
28.1
19.5
39.96
40.11
%
0.28
550
5573
52
476
1.10
0.23
6.4
3.8
—
—
—
0
0
5
38
1.32
0.23
1.4
2.0
9.90
6.34
mmol/l
—
5
27
5
39
1.28
0.23
2.4
3.2
272.80
16.58
mg/l
—
5
28
64
594
1.09
0.22
1.9
1.7
—
—
—
0
0
96
906
1.07
0.22
1.4
1.3
12.04
34.62
iu/ml
6.43
31
280
5
41
1.22
0.22
1.0
1.1
—
5.46
—
0
9
0
10
0.00
0.21
0.0
6.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
56
518
1.09
0.21
2.1
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
31
345
0.89
0.21
1.6
1.4
—
—
—
0
0
24
211
1.14
0.21
1.8
2.1
—
—
—
0
0
6
48
1.25
0.20
1.7
1.2
0.22
0.34
g/l
—
6
35
6
48
1.25
0.20
1.5
1.2
2.36
2.56
g/l
—
6
35
6
48
1.25
0.20
1.5
1.2
7.06
6.51
g/l
—
6
36
0
14
0.00
0.20
0.0
2.0
—
16.52
—
0
14
19
218
0.87
0.19
1.0
1.1
—
—
—
0
0
6
50
1.20
0.19
1.0
1.1
—
—
—
0
0
18
156
1.16
0.18
1.6
1.4
—
—
—
0
0
18
156
1.16
0.18
1.6
1.4
—
—
—
0
0
6
53
1.13
0.18
1.5
1.9
—
—
—
0
0
6
53
1.13
0.18
1.0
1.4
27.42
33.11
g/l
—
6
48
92
874
1.06
0.18
1.3
1.3
1.11
13.02
u/ml
5.48
25
337
42
388
1.09
0.17
1.2
1.2
96.33
140.93
iu/ml
0.48
15
154
5
69
0.72
0.17
2.0
2.6
104.80
106.13
mmol/l
—
5
69
5
69
0.72
0.17
2.0
2.6
4.12
4.03
mmol/l
—
5
69
5
69
0.72
0.17
2.0
2.6
—
—
—
0
0
33
303
1.09
0.15
6.4
4.6
—
—
—
0
0
22
197
1.12
0.15
1.5
1.6
—
—
—
0
0
9
78
1.16
0.15
1.2
1.1
—
—
—
0
0
7
89
0.78
0.14
1.4
1.6
—
—
—
0
0
12
139
0.86
0.14
3.7
2.0
38.77
38.03
g/l
0.42
12
123
43
458
0.93
0.13
4.5
3.8
—
—
—
0
0
166
1701
0.97
0.12
4.9
3.1
2.35
2.35
mmol/l
0.40
155
1507
10
116
0.86
0.12
2.7
4.1
27.96
25.63
mg/l
—
5
71
67
641
1.05
0.11
1.3
1.3
—
—
—
0
0
16
143
1.12
0.11
2.1
1.7
8.35
5.92
iu/l
—
6
47
22
240
0.91
0.11
1.1
1.1
—
—
—
0
0
21
192
1.10
0.11
5.2
4.7
0.19
0.37
g/l
—
9
87
5
47
1.06
0.09
1.0
1.0
—
—
—
0
0
5
48
1.04
0.09
1.0
1.6
—
—
—
0
0
25
268
0.93
0.09
2.0
2.0
—
—
—
0
0
589
5915
0.96
0.09
27.7
19.4
6.63
6.74
e9/l
0.37
579
5746
589
5914
0.96
0.08
27.6
19.4
4.45
4.49
e12/l
1.20
582
5749
29
273
1.07
0.08
1.8
1.7
—
—
—
0
0
5
60
0.83
0.08
1.0
1.1
—
—
—
0
0
5
62
0.80
0.08
1.6
1.9
—
—
—
0
0
7
66
1.06
0.08
1.6
1.4
—
—
—
0
0
55
531
1.04
0.07
8.7
7.7
0.63
1.15
mmol/l
0.48
44
434
9
84
1.07
0.07
1.2
1.2
—
—
—
0
0
18
167
1.08
0.07
1.3
1.2
—
—
—
0
0
10
89
1.13
0.07
1.4
1.6
—
—
—
0
0
589
5910
0.97
0.06
27.7
19.4
251.08
252.62
e9/l
0.21
580
5762
26
248
1.05
0.05
2.0
2.2
—
—
—
0
0
34
353
0.96
0.05
1.6
1.4
—
—
—
0
0
48
491
0.98
0.03
4.0
4.0
3.19
32.89
ug/l
1.14
37
408
37
360
1.03
0.03
2.4
2.4
3.94
6.52
e9/l
1.39
31
304
466
4649
1.01
0.02
5.9
5.4
39.41
39.45
mmol/mol
0.02
431
4326
26
267
0.97
0.01
2.5
3.6
—
—
—
0
0
13
134
0.97
0.00
1.5
1.3
—
—
—
0
0
17
174
0.98
0.00
5.1
4.3
1.32
1.31
mmol/l
0.03
17
169
10
97
1.03
0.00
6.1
3.5
3.60
4.18
e9/l
—
10
97
14
142
0.99
0.00
3.0
4.7
—
—
—
0
0
27
268
1.01
0.00
2.0
2.1
—
—
—
0
0
10
101
0.99
0.00
6.1
3.8
55.60
56.69
%
—
10
101
27
271
1.00
0.00
1.9
2.1
—
—
—
0
0
27
269
1.00
0.00
1.9
2.1
—
—
—
0
0
91
911
1.00
0.00
4.2
2.7
2.43
2.45
mmol/l
0.69
85
798
0
7
0.00
0.00
0.0
4.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
16
160
1.00
-0.00
3.0
2.0
9.41
10.33
g/l
0.54
16
143
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
80.67
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.5
—
—
—
0
0
6
60
1.00
-0.00
1.2
1.4
369.17
386.33
pmol/l
—
6
55
0
5
0.00
-0.00
0.0
13.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
7.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_HELMINTIASES and mortality.

Females

Parameter HR [95% CI] p-value
AB1_HELMINTIASES 1.881 [1.47, 2.4] < 0.001
Birth year 0.992 [0.98, 1.0] 0.076

During the follow-up period (1.1.1998 — 31.12.2019), 168 out of 2014 females with AB1_HELMINTIASES died.

Males

Parameter HR [95% CI] p-value
AB1_HELMINTIASES 2.493 [2.0, 3.1] < 0.001
Birth year 0.98 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 200 out of 1494 males with AB1_HELMINTIASES died.

Mortality risk

Mortality risk for people of age

years, who have AB1_HELMINTIASES.

N-year risk Females Males
1 0.112% 0.394%
5 0.95% 2.228%
10 2.608% 5.756%
15 4.979% 11.009%
20 8.444% 18.296%

Relationships between endpoints

Index endpoint: AB1_HELMINTIASES – Helminthiases

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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