Trematode Infections: Infections caused by infestation with worms of the class Trematoda.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
615 |
4. Check minimum number of eventsNone |
615 |
5. Include endpoints
|
657 |
6. Filter based on genotype QC (FinnGen only) |
657 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF6V3
Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 8913 | 4944 | 3842 |
Only index persons | 5959 | 3558 | 2401 |
Unadjusted period prevalence (%) | |||
Whole population | 0.13 | 0.14 | 0.11 |
Only index persons | 0.12 | 0.13 | 0.09 |
Median age at first event (years) | |||
Whole population | 33.97 | 31.17 | 37.09 |
Only index persons | 29.01 | 28.92 | 29.15 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 657 | 398 | 259 |
Unadjusted period prevalence (%) | 0.13 | 0.14 | 0.11 |
Median age at first event (years) | 36.38 | 33.25 | 41.19 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 598
- Matched controls
- 5989
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint AB1_HELMINTIASES and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
AB1_HELMINTIASES | 1.881 [1.47, 2.4] | < 0.001 |
Birth year | 0.992 [0.98, 1.0] | 0.076 |
During the follow-up period (1.1.1998 — 31.12.2019), 168 out of 2014 females with AB1_HELMINTIASES died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
AB1_HELMINTIASES | 2.493 [2.0, 3.1] | < 0.001 |
Birth year | 0.98 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 200 out of 1494 males with AB1_HELMINTIASES died.
Mortality risk
Mortality risk for people of age
years, who have AB1_HELMINTIASES.N-year risk | Females | Males |
---|---|---|
1 | 0.112% | 0.394% |
5 | 0.95% | 2.228% |
10 | 2.608% | 5.756% |
15 | 4.979% | 11.009% |
20 | 8.444% | 18.296% |
Relationships between endpoints
↥Index endpoint: AB1_HELMINTIASES – Helminthiases
GWS hits: -