Helminthiases

AB1_HELMINTIASES

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B65-B83
  • Hospital discharge: ICD-9 12[0-3]
  • Hospital discharge: ICD-8 12[0-9]|13602
  • Cause of death: ICD-10 B65-B83
  • Cause of death: ICD-9 12[0-3]
  • Cause of death: ICD-8 12[0-9]|13602

2 out of 7 registries used, show all original rules.

615

4. Check minimum number of events

None

615

5. Include endpoints

657

6. Filter based on genotype QC (FinnGen only)

657

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF6V3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8913 4944 3842
Only index persons 5959 3558 2401
Unadjusted period prevalence (%)
Whole population 0.13 0.14 0.11
Only index persons 0.12 0.13 0.09
Median age at first event (years)
Whole population 33.97 31.17 37.09
Only index persons 29.01 28.92 29.15

-FinnGen-

Key figures

All Female Male
Number of individuals 657 398 259
Unadjusted period prevalence (%) 0.13 0.14 0.11
Median age at first event (years) 36.38 33.25 41.19

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
598
Matched controls
5989
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B80
ICD-10 Finland
Enterobiasis
165.5
126.9
130
10
12340
ICD-8 Finland
Other cestode infection, Diphyllobothriasis, intestinal
+∞
113.2
105
*
12730
ICD-8 Finland
Other intestinal helminthiasis, Enterobiasis
+∞
29.4
28
*
1252A
ICD-9 Finland
Filarial infection and dracontiasis, Loiasis
+∞
22.0
21
*
B76.9
ICD-10 Finland
Hookworm disease, unspecified
+∞
15.7
15
*
12700
ICD-8 Finland
Other intestinal helminthiasis, Ascariasis
+∞
12.5
12
*
B82.9
ICD-10 Finland
Intestinal parasitism, unspecified
+∞
12.5
12
*
B83.9
ICD-10 Finland
Helminthiasis, unspecified
+∞
12.5
12
*
B70.0
ICD-10 Finland
Diphyllobothriasis
+∞
10.4
10
*
B65.3
ICD-10 Finland
Cercarial dermatitis
91.3
8.4
9
*
12899
ICD-8 Finland
Other and unspecified helminthiasis, Unspecified
+∞
8.3
8
*
B78.9
ICD-10 Finland
Strongyloidiasis, unspecified
+∞
8.3
8
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.6
7.8
57
235
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
7.6
159
1015
UJF30
NOMESCO Finland
Ileoscopy through colon
2.4
7.6
61
265
N02AX02
ATC
tramadol; systemic, rectal
1.6
7.4
230
1647
B83.8
ICD-10 Finland
Other specified helminthiases
+∞
7.3
7
*
B65.9
ICD-10 Finland
Schistosomiasis, unspecified
+∞
7.3
7
*
1234A
ICD-9 Finland
Other cestode infection, Diphyllobothriasis, intestinal
+∞
7.3
7
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
7.0
199
1384
UJF32
NOMESCO Finland
Coloscopy
1.8
6.9
134
834
M79.6
ICD-10 Finland
Pain in limb
1.6
6.7
193
1344
A02BC01
ATC
omeprazole; systemic
1.7
6.3
156
1039
B77.9
ICD-10 Finland
Ascariasis, unspecified
+∞
6.3
6
*
B81.4
ICD-10 Finland
Mixed intestinal helminthiases
+∞
6.3
6
*
12320
ICD-8 Finland
Other cestode infection, Taenia saginata infection
+∞
6.3
6
*
12720
ICD-8 Finland
Other intestinal helminthiasis, Trichuriasis
+∞
6.3
6
*
12299
ICD-8 Finland
Hydatidosis, Of unspecified site
+∞
6.3
6
*
N77.1*B80
ICD-10 Finland
Vaginitis, vulvitis and vulvovaginitis in pinworm infection
+∞
6.3
6
*
12740
ICD-8 Finland
Other intestinal helminthiasis, Other intestinal nematode infection
+∞
6.3
6
*
12699
ICD-8 Finland
Ankylostomiasis, Unspecified
+∞
6.3
6
*
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
4.6
6.2
20
45

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
265
1731
1.89
13.54
8.6
5.9
—
—
—
0
0
34
114
3.09
8.16
1.5
1.4
171.2
235.6
u/ml
1.11
22
65
321
2480
1.58
7.51
9.4
5.9
3.1
2.9
%
0.94
297
2313
311
2401
1.56
7.19
9.5
6.0
0.7
0.7
%
0.77
286
2240
335
2631
1.56
7.17
7.9
5.8
11.0
11.3
umol/l
0.18
317
2481
320
2490
1.56
7.12
9.8
6.1
8.7
8.5
%
0.60
297
2339
324
2535
1.55
6.99
9.0
5.7
55.3
56.7
%
1.30
302
2384
189
1308
1.63
6.92
9.3
6.5
—
—
—
0
0
183
1260
1.63
6.83
5.8
3.8
91.0
91.2
%
0.03
177
1234
326
2564
1.54
6.81
9.6
5.9
28.9
28.7
%
0.16
303
2400
461
3921
1.59
6.72
10.5
7.1
80.7
79.4
u/l
0.21
443
3669
340
2718
1.52
6.46
9.5
6.1
0.2
0.2
e9/l
0.59
302
2403
16
39
4.18
6.12
1.3
2.2
—
—
—
0
0
327
2618
1.50
6.01
9.0
5.7
0.6
0.6
e9/l
0.15
290
2271
328
2631
1.49
5.95
9.0
5.7
0.0
0.0
e9/l
0.50
291
2281
27
97
2.86
5.80
1.7
1.4
116.0
107.1
u/ml
—
5
16
93
561
1.77
5.61
3.5
2.8
1.8
1.8
%
0.04
80
503
72
407
1.86
5.37
2.7
2.9
11.2
10.1
g/l
1.02
66
374
44
210
2.17
5.24
1.5
1.4
—
—
—
0
0
28
109
2.64
5.20
1.7
1.5
—
—
—
0
0
331
2710
1.45
5.13
9.2
5.7
2.0
2.0
e9/l
0.12
300
2406
69
393
1.84
5.03
3.4
2.7
67.2
71.6
e9/l
0.49
54
306
94
592
1.69
4.86
4.4
2.8
6.4
7.7
umol/l
0.50
78
501
153
1096
1.52
4.61
2.2
2.0
—
—
—
0
0
237
1858
1.43
4.49
4.4
3.8
50.5
115.2
e6/l
1.35
167
1299
101
662
1.62
4.47
3.6
2.3
22.6
22.8
%
0.06
89
576
195
1480
1.45
4.38
5.8
3.8
7.4
7.4
ph
0.02
30
281
45
233
2.00
4.37
1.2
1.5
25.5
24.6
iu/l
0.06
31
193
93
601
1.64
4.36
1.9
1.6
—
—
—
0
0
359
3042
1.40
4.28
12.4
8.7
3.8
4.0
e9/l
1.18
321
2654
278
2256
1.40
4.28
8.2
5.9
1.2
1.2
mmol/l
0.06
263
2056
184
1389
1.45
4.23
3.6
3.2
—
—
—
0
0
118
818
1.54
4.11
3.1
3.1
2.3
2.6
e6/l
0.21
65
449
170
1273
1.45
4.06
2.8
2.1
2.9
3.0
mg/l
0.42
144
1085
15
48
3.17
3.95
1.4
2.4
—
—
—
0
0
286
2355
1.38
3.95
11.9
9.2
0.0
0.0
e9/l
0.72
241
1931
201
1565
1.41
3.85
3.8
3.3
68.5
110.7
e6/l
0.38
159
1203
185
1423
1.42
3.79
3.7
3.3
0.2
0.4
e6/l
2.99
139
1069
161
1211
1.44
3.72
3.8
3.5
—
—
—
0
0
240
1935
1.38
3.71
2.2
1.9
92.4
93.8
pmol/l
0.18
123
976
258
2105
1.37
3.71
7.5
4.7
35.3
35.9
g/l
0.89
243
1968
397
3472
1.36
3.63
5.2
4.5
223.2
2175.2
e6/l
—
5
59
74
475
1.63
3.57
3.2
2.3
0.2
0.2
g/l
2.86
67
448
102
707
1.52
3.54
3.5
2.3
2.4
2.4
g/l
0.52
96
655
8
13
6.21
3.51
3.9
3.8
—
—
—
0
0
152
1144
1.43
3.49
1.8
1.4
2.2
2.4
g/l
0.53
87
682
83
552
1.58
3.47
1.4
1.3
—
—
—
0
0
283
2362
1.35
3.45
3.8
2.7
108.6
107.7
ug/l
0.03
261
2166
98
679
1.52
3.41
2.4
2.3
114.7
114.8
ug/g
0.00
78
537
172
1330
1.40
3.37
5.3
4.0
—
—
—
0
0
71
459
1.61
3.34
1.2
1.2
—
—
—
0
0
34
177
1.97
3.30
10.2
9.2
—
—
—
0
0
61
381
1.66
3.28
5.4
3.9
98.1
75.9
ng/l
0.89
55
346
55
335
1.70
3.25
1.9
1.6
1.1
1.5
g/l
0.98
49
310
124
910
1.45
3.25
1.7
1.7
1151.0
1182.8
nmol/l
0.14
102
688
8
15
5.38
3.20
1.1
1.1
—
—
—
0
0
122
896
1.44
3.18
1.9
1.7
—
—
—
0
0
92
643
1.50
3.08
1.8
1.5
—
—
—
0
0
292
2478
1.32
3.08
9.8
6.5
1.2
1.2
mmol/l
0.14
252
2104
16
63
2.58
2.97
1.5
1.3
—
—
—
0
0
405
3608
1.32
2.97
5.0
4.3
—
—
—
0
0
28
142
2.02
2.94
1.4
1.4
294.6
292.5
ug/g
0.02
18
81
37
208
1.83
2.89
1.2
1.2
—
—
—
0
0
341
2977
1.30
2.85
6.4
4.6
6.6
6.6
mmol/l
0.06
323
2748
13
47
2.80
2.83
1.0
1.2
—
—
—
0
0
146
1132
1.37
2.78
2.8
1.8
1.2
1.2
mg/l
0.16
104
867
425
3830
1.31
2.77
4.9
4.0
11.9
11.6
mm/h
0.14
398
3515
47
290
1.67
2.68
1.3
1.3
—
—
—
0
0
84
595
1.47
2.65
1.7
1.3
—
—
—
0
0
138
1072
1.36
2.59
3.0
2.6
3.8
6.4
e6/l
1.76
121
939
16
69
2.35
2.50
3.1
2.6
—
—
—
0
0
83
594
1.45
2.49
19.9
21.4
1.0
1.2
inr
—
10
80
9
26
3.49
2.49
1.7
1.6
—
—
—
0
0
7
16
4.41
2.48
1.7
1.8
—
—
—
0
0
231
1944
1.29
2.46
10.3
8.7
1.3
1.2
inr
0.58
64
590
17
76
2.27
2.46
1.1
1.1
—
—
—
0
0
103
769
1.40
2.45
3.6
2.3
13.3
13.2
umol/l
0.07
98
710
131
1021
1.35
2.40
3.2
2.9
554.3
554.3
mosm/kgh2o
0.00
119
867
21
105
2.03
2.33
1.2
1.3
—
—
—
0
0
148
1822
0.76
2.31
2.9
2.8
—
—
—
0
0
7
18
3.92
2.25
1.4
1.1
—
—
—
0
0
10
36
2.81
2.21
1.8
1.4
—
—
—
0
0
7
19
3.71
2.15
1.0
1.0
—
—
—
0
0
18
88
2.07
2.13
1.1
1.1
—
—
—
0
0
26
146
1.81
2.09
1.4
1.8
38.7
40.7
nmol/l
0.23
26
141
6
15
4.03
2.04
3.2
1.3
—
—
—
0
0
117
919
1.33
2.04
4.0
3.6
418.2
317.3
ng/l
0.13
79
683
190
1593
1.27
2.03
3.0
3.0
—
—
—
0
0
468
4985
0.79
2.02
4.5
4.2
1.5
1.5
mmol/l
0.39
433
4598
8
26
3.10
2.02
1.3
1.1
—
—
—
0
0
10
38
2.66
2.01
1.3
2.8
—
39.4
—
0
5
155
1272
1.29
1.96
1.6
1.3
1.5
1.7
u/ml
0.10
28
330
58
407
1.47
1.95
1.6
1.4
—
—
—
0
0
90
684
1.37
1.95
1.2
1.2
—
—
—
0
0
471
5006
0.79
1.94
4.6
4.2
4.6
4.7
mmol/l
0.60
442
4639
187
1573
1.26
1.94
3.4
2.5
65.7
56.3
u/l
0.43
172
1451
29
173
1.71
1.93
1.2
1.6
11.9
9.7
u/l
0.35
24
140
192
1624
1.26
1.90
3.5
2.3
—
—
—
0
0
29
174
1.70
1.89
1.2
1.2
—
—
—
0
0
34
213
1.63
1.89
1.4
1.7
—
—
—
0
0
22
122
1.83
1.86
2.6
3.1
25.9
24.7
mmol/l
0.49
17
106
451
4808
0.80
1.84
4.0
3.8
1.3
1.3
mmol/l
0.21
418
4425
5
12
4.19
1.82
1.4
1.2
—
—
—
0
0
15
73
2.08
1.82
1.5
1.2
—
—
—
0
0
18
94
1.94
1.81
1.4
1.8
—
—
—
0
0
13
60
2.19
1.78
1.1
1.2
—
—
—
0
0
378
3453
1.22
1.78
3.9
3.7
—
—
—
0
0
18
95
1.92
1.77
1.1
1.1
1.1
5.4
u/ml
—
8
53
15
74
2.05
1.76
1.3
1.5
—
—
—
0
0
20
110
1.84
1.74
1.3
1.2
0.3
2.4
u/ml
—
9
48
7
24
2.94
1.72
1.6
1.8
—
—
—
0
0
218
1888
1.23
1.72
3.4
3.6
30.9
39.7
ng/l
0.53
147
1276
20
111
1.83
1.70
1.2
1.7
3.4
3.8
mmol/l
0.78
20
104
61
445
1.41
1.70
7.4
8.3
—
—
—
0
0
179
1521
1.24
1.68
3.6
3.4
7.8
7.7
mmol/l
0.12
155
1278
6
19
3.18
1.66
1.7
1.5
143.5
149.8
nmol/l
—
6
19
229
2000
1.22
1.66
2.2
2.1
—
—
—
0
0
22
127
1.76
1.66
1.3
1.7
682.6
425.4
mg/l
1.40
22
120
81
623
1.34
1.64
1.8
1.7
—
—
—
0
0
12
56
2.16
1.62
3.2
2.1
—
—
—
0
0
17
91
1.89
1.62
1.1
1.1
0.7
0.6
u/ml
—
7
45
8
32
2.52
1.60
7.6
2.7
—
—
—
0
0
18
99
1.84
1.58
1.4
2.5
4.7
9.7
umol/l
0.83
12
71
159
1342
1.24
1.58
3.7
3.3
796.3
258.8
mg/l
0.49
107
863
48
340
1.44
1.58
1.4
1.2
—
—
—
0
0
92
726
1.31
1.57
1.5
1.3
392.4
460.1
titre
0.34
21
155
12
57
2.13
1.56
3.5
2.6
18.5
21.2
nmol/l
0.47
12
52
18
100
1.82
1.54
2.2
2.3
129.1
127.9
g/l
0.07
12
73
10
44
2.29
1.54
7.1
2.7
—
—
—
0
0
7
27
2.61
1.52
1.1
1.2
—
—
—
0
0
11
51
2.18
1.51
1.0
1.1
—
—
—
0
0
148
1247
1.24
1.50
3.2
2.2
—
—
—
0
0
36
244
1.50
1.48
2.4
2.4
—
—
—
0
0
17
95
1.81
1.44
2.2
3.5
—
—
—
0
0
486
5099
0.82
1.42
5.1
4.7
2.7
2.8
mmol/l
1.28
452
4690
549
5265
1.26
1.41
20.4
15.2
139.6
139.6
mmol/l
0.31
540
5124
92
738
1.29
1.40
2.2
1.9
—
—
—
0
0
26
166
1.59
1.39
2.3
3.1
—
—
—
0
0
550
5279
1.26
1.38
20.8
15.2
3.9
4.0
mmol/l
1.29
537
5126
35
240
1.48
1.37
2.9
2.4
159.8
3040.2
u/l
1.78
17
97
547
5248
1.25
1.37
19.3
13.2
22.2
23.2
mg/l
0.32
450
4098
6
23
2.62
1.37
1.2
1.3
—
—
—
0
0
6
23
2.62
1.37
2.7
1.7
—
—
—
0
0
164
1412
1.22
1.35
4.4
4.0
7.2
10.6
mg/mmol
0.65
104
888
23
144
1.62
1.33
1.3
1.3
—
—
—
0
0
12
61
1.99
1.33
1.5
1.7
—
—
—
0
0
64
492
1.33
1.33
6.5
4.3
1.7
2.1
mmol/l
0.50
51
392
19
113
1.70
1.33
1.6
1.7
5539.3
18032.8
e6/l
1.34
13
86
289
2624
1.18
1.32
4.1
3.7
0.0
0.0
estimate
0.49
46
484
6
24
2.51
1.30
1.2
1.4
—
—
—
0
0
14
76
1.86
1.30
1.1
1.0
4.8
4.1
u/ml
—
6
24
8
34
2.37
1.29
1.3
1.3
2.0
1.8
mmol/l
—
8
34
13
69
1.90
1.29
2.0
1.9
—
—
—
0
0
46
338
1.39
1.27
4.2
4.0
7.4
7.4
ph
—
6
38
123
1035
1.23
1.26
1.6
1.7
57143316.5
20882109.5
pmol/l
0.27
98
862
8
36
2.24
1.24
2.0
1.4
0.9
1.0
g/l
—
8
36
12
64
1.89
1.18
1.2
1.1
15.1
4.9
u/ml
—
5
23
46
343
1.37
1.18
4.3
3.9
5.2
5.2
kpa
0.18
40
323
5
20
2.51
1.15
2.4
3.6
—
—
—
0
0
28
192
1.48
1.13
1.1
1.3
168.1
263.4
miu/ml
—
9
84
20
127
1.59
1.12
1.7
2.8
—
—
—
0
0
7
30
2.35
1.12
1.3
1.3
—
—
—
0
0
282
2581
1.16
1.12
4.1
3.7
0.0
0.0
estimate
0.00
44
498
283
2595
1.16
1.09
5.5
5.0
0.0
0.0
estimate
0.00
49
500
15
89
1.70
1.08
1.2
1.1
—
—
—
0
0
15
89
1.70
1.08
1.2
1.1
—
—
—
0
0
73
591
1.26
1.07
1.4
1.5
—
—
—
0
0
498
4771
1.18
1.06
5.6
4.6
1.9
2.1
mu/l
0.56
468
4357
9
46
1.97
1.04
1.1
1.2
—
—
—
0
0
5
22
2.28
1.03
1.0
1.2
111.2
187.8
iu/ml
—
5
22
9
47
1.93
1.02
1.2
1.1
—
—
—
0
0
22
147
1.51
1.01
5.9
2.8
—
—
—
0
0
144
1259
1.18
1.01
3.5
2.6
1870.5
7632.1
umol/l
2.06
127
1092
16
99
1.63
1.00
3.4
3.5
—
—
—
0
0
40
524
0.75
1.00
1.3
1.4
—
—
—
0
0
51
398
1.31
1.00
2.1
2.3
9.3
7.4
ug/l
0.25
41
350
5
23
2.18
0.98
2.4
3.3
—
—
—
0
0
5
23
2.18
0.98
1.4
1.0
—
—
—
0
0
17
108
1.59
0.97
11.3
3.1
—
—
—
0
0
49
382
1.31
0.97
5.6
4.4
1.0
0.4
%
0.37
11
94
13
77
1.70
0.95
2.2
3.3
—
—
—
0
0
13
77
1.70
0.95
1.2
1.3
—
—
—
0
0
11
62
1.79
0.94
1.5
3.0
—
—
—
0
0
11
63
1.76
0.90
3.2
1.7
—
—
—
0
0
11
63
1.76
0.90
3.2
1.7
—
—
—
0
0
11
63
1.76
0.90
3.2
1.7
—
—
—
0
0
11
63
1.76
0.90
3.2
1.7
—
—
—
0
0
421
4007
1.14
0.88
4.8
3.9
14.8
14.7
pmol/l
0.22
390
3626
52
416
1.27
0.86
6.1
4.7
0.8
0.9
%
0.01
20
133
8
45
1.79
0.84
1.3
2.4
1.0
1.1
e9/l
—
8
23
134
1183
1.17
0.84
6.0
4.7
—
—
—
0
0
156
1394
1.16
0.84
4.2
3.9
0.0
0.0
estimate
0.69
46
494
466
4479
1.14
0.80
22.8
16.2
13.8
13.6
%
1.02
460
4402
132
1171
1.16
0.78
4.5
3.9
1.0
1.0
kg/l
0.31
16
161
7
123
0.56
0.78
1.1
1.1
—
—
—
0
0
34
261
1.32
0.78
2.7
2.9
0.1
0.1
e6/l
0.02
34
253
12
75
1.61
0.75
2.8
1.7
—
—
—
0
0
12
75
1.61
0.75
2.5
3.0
2.9
60.1
u/ml
0.54
12
69
9
56
1.62
0.72
3.4
2.5
—
—
—
0
0
41
328
1.27
0.71
3.1
2.6
—
—
—
0
0
5
26
1.93
0.70
1.4
1.1
—
—
—
0
0
7
41
1.71
0.70
22.1
3.4
10.7
10.9
%
—
7
41
10
61
1.65
0.69
6.6
4.6
—
—
—
0
0
53
439
1.23
0.68
5.7
3.7
4.7
4.5
kpa
0.36
53
426
7
42
1.67
0.68
2.0
2.6
—
—
—
0
0
148
1339
1.14
0.67
4.8
4.6
1.8
2.5
ug/l
1.33
135
1202
164
1494
1.13
0.67
2.4
2.1
205.4
248.9
u/l
0.30
154
1414
31
241
1.30
0.67
11.1
10.0
—
—
—
0
0
12
79
1.53
0.63
1.6
1.6
—
—
—
0
0
12
79
1.53
0.63
1.2
1.1
—
—
—
0
0
47
389
1.22
0.62
6.0
4.9
0.0
0.1
%
3.53
18
119
8
49
1.64
0.62
1.4
1.2
—
—
—
0
0
166
1522
1.12
0.61
1.6
1.5
—
—
—
0
0
0
21
0.00
0.60
0.0
3.5
—
33.1
—
0
16
8
52
1.54
0.59
1.5
1.3
—
—
—
0
0
48
401
1.21
0.59
4.9
3.2
—
—
—
0
0
146
1332
1.12
0.59
1.7
1.6
1.4
1.4
mmol/l
0.18
127
1128
21
158
1.34
0.58
5.4
7.0
1.3
1.4
mg/l
0.58
21
146
562
5507
1.14
0.56
13.9
9.9
26.5
25.7
u/l
0.45
551
5301
13
90
1.45
0.55
1.1
1.1
—
13.1
—
0
7
88
781
1.15
0.55
3.0
2.9
0.6
0.8
ug/l
1.00
62
503
6
38
1.58
0.54
1.2
2.2
—
666.3
—
0
15
124
1127
1.12
0.54
1.5
1.5
18.3
20.7
nmol/l
1.21
110
952
133
1453
0.89
0.54
3.7
3.4
—
—
—
0
0
9
63
1.43
0.52
1.2
1.2
—
—
—
0
0
16
118
1.36
0.50
1.4
2.0
—
—
—
0
0
149
1375
1.11
0.50
3.7
3.1
1461.7
1394.0
ng/l
0.07
128
1165
130
1414
0.90
0.49
3.8
3.7
—
—
—
0
0
15
110
1.37
0.49
3.3
3.0
1.8
2.8
mmol/l
—
8
74
13
93
1.41
0.48
2.2
1.8
—
—
—
0
0
5
85
0.59
0.45
1.4
3.0
—
—
—
0
0
466
4541
1.09
0.44
24.7
16.9
331.3
332.7
g/l
2.52
466
4507
16
121
1.33
0.44
1.4
1.2
—
—
—
0
0
6
92
0.65
0.42
7.7
3.4
13.0
25.9
u/ml
—
6
92
8
58
1.38
0.41
1.5
1.7
31.4
32.4
pg
—
8
58
35
296
1.19
0.41
1.5
1.1
—
77.3
—
0
7
5
33
1.52
0.41
1.4
2.4
0.1
0.2
e9/l
—
5
27
0
15
0.00
0.41
0.0
2.9
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
254
2424
1.08
0.40
5.5
4.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.8
—
—
—
0
0
5
35
1.43
0.39
1.4
2.3
349.0
573.7
e6/l
—
5
27
9
66
1.37
0.38
1.2
1.4
275.7
284.2
mosm/kgh2o
—
9
50
36
308
1.18
0.38
3.1
2.2
—
—
—
0
0
31
264
1.18
0.35
4.9
3.8
—
—
—
0
0
6
43
1.40
0.35
1.0
1.1
92.2
35.6
mg/l
—
6
32
6
43
1.40
0.35
1.3
1.3
—
—
—
0
0
53
472
1.13
0.35
6.3
3.9
—
—
—
0
0
21
173
1.22
0.33
3.1
2.6
—
—
—
0
0
6
46
1.31
0.33
1.0
1.4
—
—
—
0
0
29
338
0.85
0.33
1.6
1.4
—
—
—
0
0
484
4922
0.94
0.29
4.6
4.3
5.9
5.9
mmol/l
0.09
447
4486
42
374
1.13
0.29
6.6
4.9
0.1
0.2
%
0.26
13
106
22
186
1.19
0.28
4.4
4.8
—
—
—
0
0
17
140
1.22
0.27
2.1
1.6
8.4
5.9
iu/l
—
6
46
553
5464
1.08
0.26
16.1
12.4
—
—
—
0
0
46
415
1.12
0.26
1.3
1.4
—
—
—
0
0
5
38
1.32
0.23
2.4
3.3
272.8
16.6
mg/l
—
5
28
5
38
1.32
0.23
1.4
2.0
9.9
6.3
mmol/l
—
5
27
95
897
1.07
0.22
1.4
1.3
12.3
34.7
iu/ml
6.10
29
275
23
262
0.87
0.21
2.1
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
7.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
16.5
—
0
14
22
193
1.14
0.20
1.5
1.6
—
—
—
0
0
6
50
1.20
0.19
1.0
1.1
—
—
—
0
0
63
589
1.08
0.19
1.9
1.7
—
—
—
0
0
6
53
1.13
0.18
1.0
1.4
27.4
33.1
g/l
—
6
48
42
455
0.92
0.18
4.6
3.9
—
—
—
0
0
19
216
0.88
0.18
1.0
1.1
—
—
—
0
0
18
157
1.15
0.17
1.6
1.5
—
—
—
0
0
33
301
1.10
0.17
6.4
4.6
—
—
—
0
0
91
867
1.06
0.17
1.3
1.3
1.1
13.1
u/ml
5.48
25
334
5
70
0.71
0.16
2.0
2.6
4.1
4.0
mmol/l
—
5
70
5
70
0.71
0.16
2.0
2.6
104.8
106.1
mmol/l
—
5
70
5
70
0.71
0.16
2.0
2.6
—
—
—
0
0
491
4857
1.04
0.16
21.6
14.2
39.7
39.9
%
0.24
370
3631
23
207
1.12
0.15
1.9
2.2
—
—
—
0
0
9
81
1.11
0.15
1.2
1.1
—
—
—
0
0
7
88
0.79
0.14
1.4
1.6
—
—
—
0
0
29
267
1.09
0.13
1.8
1.7
—
—
—
0
0
12
138
0.87
0.13
3.7
2.0
38.8
37.9
g/l
0.54
12
119
41
384
1.07
0.13
1.2
1.2
95.0
137.4
iu/ml
0.41
14
150
53
503
1.06
0.12
2.1
1.4
—
—
—
0
0
18
162
1.11
0.12
1.3
1.2
—
—
—
0
0
583
5859
0.96
0.11
27.8
19.5
6.6
6.7
e9/l
0.31
573
5691
17
153
1.11
0.11
1.5
1.4
—
—
—
0
0
17
153
1.11
0.11
1.5
1.4
—
—
—
0
0
10
115
0.87
0.10
2.7
4.1
28.0
25.6
mg/l
—
5
71
583
5857
0.96
0.10
27.8
19.5
4.5
4.5
e12/l
1.26
576
5693
55
526
1.05
0.10
8.7
7.8
0.6
1.2
mmol/l
0.48
44
426
5
46
1.09
0.09
1.0
1.0
—
—
—
0
0
5
48
1.04
0.09
1.0
1.6
—
—
—
0
0
25
268
0.93
0.09
2.5
3.6
—
—
—
0
0
5
60
0.83
0.08
1.0
1.1
—
—
—
0
0
22
236
0.93
0.08
1.1
1.1
—
—
—
0
0
583
5853
0.96
0.08
27.8
19.5
251.2
252.4
e9/l
0.16
574
5706
7
64
1.09
0.08
1.6
1.4
—
—
—
0
0
13
143
0.91
0.07
3.1
4.7
—
—
—
0
0
166
1688
0.98
0.07
4.9
3.1
2.3
2.4
mmol/l
0.34
153
1484
8
78
1.03
0.07
1.3
1.2
—
—
—
0
0
25
265
0.94
0.07
2.0
2.1
—
—
—
0
0
9
103
0.87
0.06
6.7
3.8
56.4
56.6
%
—
9
103
65
633
1.03
0.05
1.3
1.3
—
—
—
0
0
10
90
1.11
0.05
1.4
1.5
—
—
—
0
0
25
263
0.95
0.05
2.0
2.1
—
—
—
0
0
25
262
0.95
0.05
2.1
2.1
—
—
—
0
0
34
350
0.97
0.03
1.6
1.4
—
—
—
0
0
20
192
1.04
0.02
5.3
4.7
0.2
0.4
g/l
—
9
87
48
489
0.98
0.02
4.0
4.1
3.2
32.8
ug/l
1.14
37
409
91
903
1.01
0.01
4.2
2.7
2.4
2.4
mmol/l
0.74
85
790
17
173
0.98
0.00
5.1
4.3
1.3
1.3
mmol/l
0.02
17
168
36
356
1.01
0.00
2.5
2.4
4.0
4.1
e9/l
0.09
30
282
24
242
0.99
0.00
2.0
2.2
—
—
—
0
0
462
4616
1.00
0.00
6.0
5.5
39.4
39.5
mmol/mol
0.02
427
4293
13
129
1.01
0.00
1.5
1.3
—
—
—
0
0
9
99
0.91
0.00
6.7
3.5
3.8
4.2
e9/l
—
9
99
0
9
0.00
0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
0.00
0.0
4.3
—
—
—
0
0
0
6
0.00
0.00
0.0
4.3
—
—
—
0
0
5
53
0.94
0.00
1.4
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
13.6
—
—
—
0
0
0
7
0.00
0.00
0.0
4.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
80.7
—
0
6

Mortality – FinRegistry

Association

Association between endpoint AB1_HELMINTIASES and mortality.

Females

Parameter HR [95% CI] p-value
AB1_HELMINTIASES 1.881 [1.47, 2.4] < 0.001
Birth year 0.992 [0.98, 1.0] 0.076

During the follow-up period (1.1.1998 — 31.12.2019), 168 out of 2014 females with AB1_HELMINTIASES died.

Males

Parameter HR [95% CI] p-value
AB1_HELMINTIASES 2.493 [2.0, 3.1] < 0.001
Birth year 0.98 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 200 out of 1494 males with AB1_HELMINTIASES died.

Mortality risk

Mortality risk for people of age

years, who have AB1_HELMINTIASES.

N-year risk Females Males
1 0.112% 0.394%
5 0.95% 2.228%
10 2.608% 5.756%
15 4.979% 11.009%
20 8.444% 18.296%

Relationships between endpoints

Index endpoint: AB1_HELMINTIASES – Helminthiases

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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