Schistosomiasis [bilharziasis]

AB1_SCHISTOSOMIASIS

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — B65 Hospital discharge: ICD-9 — 120 Hospital discharge: ICD-8 — 120 Cause of death: ICD-10 — B65 Cause of death: ICD-9 — 120 Cause of death: ICD-8 — 120 2 out of 7 registries used, show all original rules.	43
4. Check minimum number of events None	43
5. Include endpoints None	43
6. Filter based on genotype QC (FinnGen only)	43

Control definitions (FinnGen only)

Control exclude: AB1_HELMINTIASES

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF6V3

NAME	AB1_SCHISTOSOMIASIS
CONTROL_EXCLUDE	AB1_HELMINTIASES
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	B65
HD_ICD_9	120
HD_ICD_8	120
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	B65
COD_ICD_9	120
COD_ICD_8	120
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Schistosomiasis [bilharziasis] based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	481	208	261
Only index persons	382	169	213
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	36.69	33.44	39.71
Only index persons	34.37	32.06	36.20

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	43	14	29
Unadjusted period prevalence (%)	0.01	0.00	0.01
Median age at first event (years)	50.38	38.02	56.35

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3048929) Epstein Barr virus Ab [Presence] in Serum

6.76

2.80

1.2

1.3

—

(3021387) Prolactin [Units/volume] in Serum or Plasma

6.11

2.27

1.6

1.4

364.0

307.6

mu/l

—

(42870588) Differential panel, method unspecified - Blood

116

2.35

1.93

6.9

6.3

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

180

2.34

1.88

9.5

7.6

11.7

10.2

umol/l

0.59

170

(3000494) Fungus identified in Specimen by Culture

2.57

1.51

1.8

1.6

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

3.39

1.48

1.2

—

(3023368) Bacteria identified in Blood by Culture

2.17

1.47

6.3

4.8

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

2.68

1.46

1.9

1.3

—

(3031040) Bacteria [#/volume] in Urine by Automated count

212

2.13

1.46

4.0

4.2

—

684.4

—

(3019225) pH of Specimen

2.86

1.42

2.8

6.8

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

138

2.02

1.39

5.6

4.0

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

2.50

1.33

8.5

9.3

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

3.00

1.32

2.4

2.3

—

(3022145) Colonoscopy Study observation

2.35

1.26

1.1

1.2

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

119

1.88

1.12

5.2

3.3

29.7

28.9

u/l

0.10

111

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.26

1.09

1.1

1.7

—

(3037467) Urinalysis macro (dipstick) panel - Urine

226

1.87

1.06

3.6

3.8

—

(1761868) Lipid panel - Serum or Plasma

149

0.50

1.05

2.9

2.8

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

280

2.02

1.05

10.3

7.4

84.5

77.1

u/l

0.58

262

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.96

1.02

2.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

2.00

1.01

2.5

2.2

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

124

1.78

0.96

2.7

3.0

—

(3021589) Normoblasts [#/volume] in Blood

156

1.68

0.84

9.3

10.1

0.0

e9/l

0.50

121

(3024561) Albumin [Mass/volume] in Serum or Plasma

138

1.68

0.82

5.6

4.2

35.8

35.9

g/l

0.03

131

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

0.00

0.82

0.0

3.7

—

4.4

—

(3032080) INR in Blood by Coagulation assay

129

1.68

0.82

8.9

8.5

1.1

1.3

inr

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.84

0.81

1.1

1.9

—

(3003694) ABO and Rh group [Type] in Blood

1.76

0.81

1.4

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

2.00

0.78

1.7

366.9

350.5

nmol/l

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.00

0.78

1.1

1.7

—

(40758558) Short blood count panel - Blood

1.68

0.73

8.6

5.6

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.89

0.68

2.0

2.4

—

(4010399)

1.89

0.68

1.0

1.4

—

(3044640) Blood type and Crossmatch panel - Blood

1.64

0.67

3.4

2.2

—

(3042936) Bacteria identified in Isolate by Culture

1.66

0.64

2.6

1.7

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.89

0.62

1.5

1.6

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.67

0.59

2.9

4.3

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.72

0.58

1.2

1.5

—

(3026782) Osmolality of Urine

1.63

0.57

2.8

2.5

587.1

601.1

mosm/kgh2o

0.10

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.67

0.57

1.7

1.6

—

(40768804) Tissue Pathology biopsy report

132

1.48

0.51

2.1

1.8

—

(40760892) CBC W Ordered Manual Differential panel - Blood

1.55

0.49

5.5

4.8

—

(36304419) Bacteria [Presence] in Urine

1.51

0.49

2.1

2.5

—

(3023520) Reticulocytes [#/volume] in Blood

1.69

0.45

5.2

2.7

62.3

63.3

e9/l

—

(4035726)

1.63

0.44

1.4

1.3

—

(3000492) Spirometry study

1.58

0.43

1.6

1.5

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

0.00

0.42

0.0

5.5

—

1.5

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

0.00

0.42

0.0

6.0

—

130.4

—

(3026008) Bacteria identified in Urine by Culture

1.44

0.39

1.8

2.7

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.39

0.35

1.5

1.7

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

102

1.39

0.35

1.5

2.0

297.3

188.3

u/l

0.38

(3015736) pH of Urine

121

1.37

0.35

2.9

4.1

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.38

0.33

1.6

1.5

—

(3013512) EKG study

1.38

0.32

5.7

4.5

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

143

1.31

0.29

6.8

6.5

1.2

mmol/l

1.28

129

(3021960) Folate [Moles/volume] in Serum or Plasma

0.67

0.29

1.2

1.6

14.1

20.8

nmol/l

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

338

1.40

0.25

17.7

13.2

87.4

82.6

ml/min/173m2

0.95

282

(3024731) MCV [Entitic volume]

391

0.76

0.24

31.0

20.0

91.2

91.1

0.04

385

(3026361) Erythrocytes [#/volume] in Blood

391

0.76

0.24

31.2

20.1

4.5

e12/l

0.26

384

(3000963) Hemoglobin [Mass/volume] in Blood

391

0.76

0.24

31.3

20.2

134.3

137.4

g/l

0.57

385

(3035941) MCH [Entitic mass]

391

0.76

0.24

31.1

20.0

30.4

0.01

385

(3044889) 12 lead EKG panel

246

1.26

0.23

3.8

3.7

—

(3007461) Platelets [#/volume] in Blood

390

0.78

0.23

31.2

20.1

218.7

241.4

e9/l

1.18

383

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

0.00

0.21

0.0

1.7

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.21

0.0

1.2

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.2

—

(3020891) Body temperature

0.00

0.21

0.0

5.1

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

0.00

0.21

0.0

4.4

—

25.3

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

0.21

0.0

4.4

—

53.7

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.21

0.0

1.5

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

130

1.24

0.19

3.7

4.2

—

(3003338) MCHC [Mass/volume]

305

0.85

0.12

21.9

17.5

334.0

333.2

g/l

0.19

305

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

227

1.13

0.08

2.8

3.0

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

359

1.22

0.08

22.3

16.0

139.4

139.7

mmol/l

0.35

350

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

132

0.87

0.08

4.8

5.0

21.2

21.3

—

(3020682) Albumin/Creatinine [Ratio] in Urine

104

1.08

0.01

3.4

4.0

0.7

6.1

mg/mmol

—

(3041096) Erythrocytes [Presence] in Urine by Automated

101

0.99

0.00

3.3

3.5

—

(3009542) Hematocrit [Volume Fraction] of Blood

321

0.99

0.00

20.5

14.8

40.1

41.1

0.40

242

(3002385) Erythrocyte distribution width [Ratio]

309

1.01

0.00

24.0

16.6

14.1

13.7

0.55

301

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

235

0.95

0.00

6.8

3.1

43.7

47.3

u/l

0.11

220

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

2.0

—

0.8

—

(44806118)

0.00

0.0

1.4

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

2.4

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.0

1.1

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

5.0

—

104.4

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

2.4

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

2.4

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

0.0

1.4

—

4.9

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.0

1.2

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.0

3.7

—

(3044941) Cell count panel - Synovial fluid

0.00

0.0

1.2

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.2

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.0

1.6

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.0

1.2

—

91.6

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.3

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

0.0

1.4

—

7.4

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

380

1.00

0.00

13.7

10.4

29.2

25.8

u/l

0.70

366

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

2.0

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

1.4

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(42870365) C reactive protein [Mass/volume] in Blood by High sensitivity method

0.00

0.0

1.4

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

(1616796) Gas panel - Central venous blood

0.00

0.0

1.4

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

378

1.05

0.00

21.5

16.4

74.8

78.8

umol/l

0.83

378

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.1

—

(44790047)

0.00

0.0

1.4

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.0

1.1

—

(40761511) CBC panel - Blood by Automated count

371

0.98

0.00

19.7

12.8

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.0

1.6

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

2.0

—

(44790049)

0.00

0.0

1.4

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.0

1.2

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

0.0

2.0

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.6

—

(44790048)

0.00

0.0

1.4

—

(3000012) Reticulocyte production index

0.00

0.0

2.0

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

5.0

—

(3028626) Oxygen [Partial pressure] in Capillary blood

0.00

0.0

1.9

—

8.4

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.6

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

5.0

—

4.0

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

2.4

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.0

1.4

—

(40768443) Skin Pathology biopsy report

0.00

0.0

1.0

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

2.0

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.0

5.5

—

8.7

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

2.4

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3024928) Oxygen saturation in Venous blood

0.00

0.0

8.8

—

(4094501)

0.00

0.0

1.0

—

(3028271) Lactate [Moles/volume] in Capillary blood

0.00

0.0

1.4

—

1.4

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.5

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.0

5.5

—

1.6

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

2.4

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

Mortality – FinRegistry

↥

Association

Association between endpoint AB1_SCHISTOSOMIASIS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have AB1_SCHISTOSOMIASIS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: AB1_SCHISTOSOMIASIS – Schistosomiasis [bilharziasis]

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Schistosomiasis [bilharziasis]

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints