Other specified/unspecified systemic involvement of connective tissue

M13_CONNECTNAS

connective tissue disease: A disorder characterized by abnormalities in one or more of the elements of the connective tissues, typically associated with genetic defects.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M35.8, M35.9
  • Hospital discharge: ICD-9 710[8-9]
  • Hospital discharge: ICD-8 7349[1-9]
  • Cause of death: ICD-10 M35.8, M35.9
  • Cause of death: ICD-9 710[8-9]
  • Cause of death: ICD-8 7349[1-9]

2 out of 7 registries used, show all original rules.

2270

4. Check minimum number of events

None

2270

5. Include endpoints

None

2270

6. Filter based on genotype QC (FinnGen only)

2270

Control definitions (FinnGen only)

Control exclude
M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 14013 10660 3215
Only index persons 11603 9189 2414
Unadjusted period prevalence (%)
Whole population 0.25 0.31 0.09
Only index persons 0.29 0.34 0.09
Median age at first event (years)
Whole population 52.98 51.92 56.35
Only index persons 50.88 50.14 53.68

-FinnGen-

Key figures

All Female Male
Number of individuals 2270 1802 468
Unadjusted period prevalence (%) 0.53 0.61 0.21
Median age at first event (years) 50.21 48.62 56.33

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2074
Matched controls
20737
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P01BA02
ATC
hydroxychloroquine; oral
36.2
323.0
1216
781
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
440.1
323.0
445
13
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
4503599627370496.0
323.0
1733
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
19.2
323.0
1086
1123
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
3086.1
297.0
280
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
12.2
288.1
566
618
H02AB06
ATC
prednisolone; systemic
5.5
274.8
1522
6899
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
8.6
254.4
618
970
M35.8
ICD-10 Finland
Other specified systemic involvement of connective tissue
+∞
217.6
205
*
L04AX01
ATC
azathioprine; systemic
13.2
205.3
380
347
M35.1
ICD-10 Finland
Other overlap syndromes
+∞
186.3
176
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.7
164.1
1085
4761
I73.0
ICD-10 Finland
Raynaud syndrome
25.1
155.8
223
99
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
7.0
147.9
398
676
C08CA05
ATC
nifedipine; systemic
6.9
130.5
354
601
XPX04
NOMESCO Finland
Angioscopy
146.6
129.9
137
10
M35.3
ICD-10 Finland
Polymyalgia rheumatica
20.7
127.6
194
103
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
121.9
1126
5857
XX9XE
NOMESCO Finland
Other ultrasound examination
40.0
112.1
142
38
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
+∞
103.0
98
*
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
11.8
100.7
192
177
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.7
97.3
368
909
H02AB07
ATC
prednisone; oral
3.6
96.0
508
1701
M34.1
ICD-10 Finland
CR(E)ST syndrome
938.9
92.6
90
*
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
7.2
90.5
232
355
L04AA06
ATC
mycophenolic acid; systemic
17.7
88.3
141
85
73491
ICD-8 Finland
Diffuse diseases of connective tissue, Collagenosis NUD
+∞
87.1
83
*
L88
ICPC
Rheumatoid/seropositive arthritis
7.1
86.0
223
346
7109X
ICD-9 Finland
Diffuse diseases of connective tissue, Unspecified diffuse connective tissue disease
+∞
83.9
80
*
M05BA04
ATC
alendronic acid; oral
4.4
82.6
332
862
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.8
80.0
290
677
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
6.2
79.8
228
403
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
+∞
79.7
76
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.6
76.7
756
3757
M25.5
ICD-10 Finland
Pain in joint
2.5
74.9
780
3987
M79.0
ICD-10 Finland
Rheumatism, unspecified
6.5
73.0
201
337
H04.10
ICD-10 Finland
Dry eye syndrome
3.7
70.4
346
1067
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
5.1
69.4
234
502
SBA10
NOMESCO Finland
Measurement of excretion of saliva
15.9
65.8
109
72
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.7
64.8
319
980
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
+∞
63.9
61
*
M13.9
ICD-10 Finland
Arthritis, unspecified
4.1
62.2
261
696
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.2
61.7
1023
6386
R50.9
ICD-10 Finland
Fever, unspecified
2.9
55.1
394
1571
A02BC02
ATC
pantoprazole; systemic
2.1
54.6
1429
10598
M35.7
ICD-10 Finland
Hypermobility syndrome
30.2
54.4
73
25
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
8.3
54.1
124
158
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
53.4
51
*
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
+∞
52.3
50
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
52.2
548
2707
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.4
50.9
275
900
ZX120
NOMESCO Finland
Intravenous
3.2
49.2
283
968
R06.0
ICD-10 Finland
Dyspnoea
2.2
48.5
597
3168
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
6.0
48.1
139
246
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.4
47.2
480
2316
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.1
45.1
273
964
N03AX16
ATC
pregabalin; oral
2.2
44.9
568
3030
UJF32
NOMESCO Finland
Coloscopy
2.2
44.7
593
3232
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.9
43.1
191
529
N02AX02
ATC
tramadol; systemic, rectal
1.9
42.7
911
5983
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
9.1
42.4
91
104
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.4
42.1
437
2114
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
6.1
41.0
116
200
M34.0
ICD-10 Finland
Progressive systemic sclerosis
+∞
40.8
39
*
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
5.8
40.7
119
214
XQ841
NOMESCO Finland
Examination of dermatosis with microscope
89.9
39.9
44
5
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.1
39.6
243
863
R4120
NOMESCO Finland
Occupational therapy
3.6
38.9
190
570
PAW37
NOMESCO Finland
Biopsy of temporal artery
52.2
38.7
46
9
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.6
38.6
319
1363
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.5
38.4
326
1415
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
38.1
486
2575
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
7.6
37.6
90
123
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.0
36.9
237
865
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
101.9
36.8
40
*
L04AD01
ATC
ciclosporin; systemic
7.6
36.3
87
119
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
6.8
35.7
92
140
E0000UV
ATC
NA
1.8
35.7
870
5872
A07EC01
ATC
sulfasalazine; oral, rectal
2.9
35.3
235
879
QC6S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in hand
59.7
35.3
41
7
M33.2
ICD-10 Finland
Polymyositis
183.1
34.8
36
*
C03CA01
ATC
furosemide; systemic
2.0
34.6
547
3151
M33.9
ICD-10 Finland
Dermatopolymyositis, unspecified
+∞
34.5
33
*
M79.7
ICD-10 Finland
Fibromyalgia
4.2
34.4
138
349
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.5
34.4
168
504
A02BC03
ATC
lansoprazole; oral
1.9
34.2
669
4167
73410
ICD-8 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
122.1
33.8
36
*
H02AB04
ATC
methylprednisolone; systemic
2.2
33.6
374
1850
7108X
ICD-9 Finland
Diffuse diseases of connective tissue, Other specified diffuse diseases of connective tissue
+∞
33.4
32
*
M32
ICD-10 Finland
Systemic lupus erythematosus
172.7
32.8
34
*
XG410
NOMESCO Finland
Flow-volume spirometry
4.1
32.7
133
341
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.5
32.5
279
1211
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
32.1
293
1313
TEA00
NOMESCO Finland
Biopsy of lip
10.8
32.0
62
59
M35.5
ICD-10 Finland
Multifocal fibrosclerosis
321.8
31.9
32
*
NH3EA
NOMESCO Finland
Feet X-ray examination with load
5.9
31.9
92
163
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
5.2
31.5
100
199
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.8
31.4
141
394
L93.0
ICD-10 Finland
Discoid lupus erythematosus
18.9
31.4
48
26
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
6.3
31.4
85
139
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
31.3
847
5837
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
8.0
31.3
72
93
N03AX12
ATC
gabapentin; oral
2.2
31.3
361
1813
J01MA12
ATC
levofloxacin; systemic
2.1
31.3
397
2079
M01AH01
ATC
celecoxib; oral (coxibs)
2.1
31.1
432
2347
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
31.1
457
2542
TGC00
NOMESCO Finland
Bronchial lavation
5.6
30.8
92
170
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
8.0
30.8
71
92
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.6
30.6
244
1013
ELA30
NOMESCO Finland
Biopsy of salivary gland
38.7
30.3
38
10
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
4.6
30.2
109
249
M05BA07
ATC
risedronic acid; oral
4.3
29.8
116
285
L04AA01
ATC
[U] ciclosporin; systemic
8.4
29.6
66
81
J01FF01
ATC
clindamycin; systemic
1.8
29.4
590
3669
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.9
28.6
183
665
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.6
28.2
220
901
L04AA13
ATC
leflunomide; oral
4.5
27.9
102
236
M34.8
ICD-10 Finland
Other forms of systemic sclerosis
285.2
27.8
28
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
27.7
366
1936
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
9.4
27.5
57
62
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.1
27.3
347
1806
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
5.4
27.2
83
158
A02BC01
ATC
omeprazole; systemic
1.8
27.0
587
3729
M05BX04
ATC
denosumab; parenteral
3.3
26.8
140
442
N02BE01
ATC
paracetamol; systemic, rectal
1.9
26.7
1776
15659
L99
ICPC
Musculoskeletal disease other
6.0
26.7
75
129
H19.3*M35.0
ICD-10 Finland
Keratoconjunctivitis sicca
46.4
26.5
32
7
R51.80
ICD-10 Finland
Headache
2.1
26.3
352
1868
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.3
25.9
135
425
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
25.6
377
2081
M33.1
ICD-10 Finland
Other dermatomyositis
+∞
25.0
24
*
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
24.8
799
5678
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
24.8
751
5247
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
24.1
214
939
GD1AD
NOMESCO Finland
Thorax CT examination
3.6
24.1
112
323
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.5
24.0
117
350
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
+∞
24.0
23
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
23.7
531
3382
N06AX21
ATC
duloxetine; oral
2.2
23.4
253
1223
J01DB01
ATC
cefalexin; oral
1.7
23.2
1655
14417
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
23.1
925
6922
A07AA02
ATC
nystatin; oral
2.7
23.1
168
661
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
4.9
23.0
77
163
NXL00
NOMESCO Finland
Biopsy of muscle
22.3
23.0
33
15
73498
ICD-8 Finland
Diffuse diseases of connective tissue, Alii definiti
+∞
23.0
22
*
P01BA01
ATC
chloroquine; systemic
15.7
22.8
37
24
N06AA09
ATC
amitriptyline; systemic
2.2
22.7
244
1175
M35
ICD-10 Finland
Other systemic involvement of connective tissue
121.4
22.6
24
*
ZX140
NOMESCO Finland
Intra articular
8.9
22.1
47
54
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.0
22.1
134
471
J01MA14
ATC
moxifloxacin; systemic
2.4
21.7
203
913
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
6.4
21.6
57
91
M01AC06
ATC
meloxicam; systemic, rectal
1.6
21.5
769
5560
J01FA06
ATC
roxithromycin; oral
1.6
21.5
850
6307
A02BC05
ATC
esomeprazole; systemic
1.6
21.4
839
6208
M79.1
ICD-10 Finland
Myalgia
2.0
21.4
295
1576
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
21.4
601
4070
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
17.6
21.3
33
19
D68.8
ICD-10 Finland
Other specified coagulation defects
7.5
21.2
50
68
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
4.2
21.2
81
197
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
21.2
380
2239
M05BB03
ATC
alendronic acid and colecalciferol; oral
4.3
21.0
79
189
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.7
20.9
150
582
J02AC01
ATC
fluconazole; systemic
1.6
20.9
941
7191
J01DA01
ATC
[U] cefalexin; systemic
1.6
20.9
1286
10590
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
4.2
20.9
80
195
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
+∞
20.9
20
*
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
3.0
20.7
126
444
J01MA02
ATC
ciprofloxacin; systemic
1.6
20.7
733
5276
C08CA02
ATC
felodipine; oral
2.3
20.6
197
896
NJ3CG
NOMESCO Finland
Extensive MRI examination of extremities with median high magnet
22.6
20.4
29
13
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.5
20.3
161
665
NF1AA
NOMESCO Finland
Hip X-ray examination
2.4
20.3
186
829
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.1
20.2
238
1191
D64.9
ICD-10 Finland
Anaemia, unspecified
2.3
20.2
191
864
R03AC02
ATC
salbutamol; inhalant
1.5
20.0
1073
8509
73499
ICD-8 Finland
Diffuse diseases of connective tissue, Other and unspecified
+∞
19.8
19
*
C07AB07
ATC
bisoprolol; oral
1.6
19.7
852
6414
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.4
19.7
175
767
318
Kela drug reimbursment
Teriparatide
13.3
19.7
34
26
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.2
19.7
218
1060
K90.0
ICD-10 Finland
Coeliac disease
3.8
19.3
84
230
A02BA02
ATC
ranitidine; systemic
1.8
19.3
398
2447
M79.6
ICD-10 Finland
Pain in limb
1.6
19.2
713
5162
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.7
19.0
85
238
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
19.0
664
4737
M01AH02
ATC
rofecoxib; oral
2.0
19.0
282
1547
M60.9
ICD-10 Finland
Myositis, unspecified
12.9
18.9
33
26
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
8.8
18.9
40
46
C08CA01
ATC
amlodipine; oral
1.6
18.8
637
4502
M31.3
ICD-10 Finland
Wegener granulomatosis
+∞
18.8
18
*
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
8.8
18.4
39
45
S18
ICPC
Laceration/cut
1.5
18.3
780
5821
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.5
18.3
154
656
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
6.4
18.2
48
77
H26.3
ICD-10 Finland
Drug-induced cataract
11.1
18.2
34
31
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
3.4
18.2
89
269
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.5
17.9
145
604
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
17.8
355
2155
J99.1
ICD-10 Finland
Respiratory disorders in other diffuse connective tissue disorders
+∞
17.7
17
*
G73.7*M35.0
ICD-10 Finland
Myopathy in sicca syndrome [Sjögren]
+∞
17.7
17
*
WZA10
NOMESCO Finland
Long statement of health and health related matters
5.6
17.5
51
93
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.0
17.5
242
1290
J01AA02
ATC
doxycycline; systemic
1.6
17.4
1580
13902
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.3
17.4
168
768
M81.4
ICD-10 Finland
Drug-induced osteoporosis
14.0
17.3
29
21
M54.5
ICD-10 Finland
Low back pain
1.6
17.3
655
4741
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
17.2
309
1810
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.3
17.2
164
746
R4110
NOMESCO Finland
Physiotherapy
1.6
17.1
510
3474
H05AA02
ATC
teriparatide; parenteral
13.3
17.0
29
22
R06AE07
ATC
cetirizine; oral
1.5
16.9
913
7147
R52.2
ICD-10 Finland
Other chronic pain
3.4
16.7
83
254
G73.7
ICD-10 Finland
Myopathy in other diseases classified elsewhere
+∞
16.7
16
*
7102A
ICD-9 Finland
Diffuse diseases of connective tissue, Sicca syndrome[SYNDROMA SICCUM PRIMARIUM]
+∞
16.7
16
*
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.9
16.7
68
177
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
90.8
16.6
18
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.2
16.5
181
877
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
16.4
325
1963
L50.9
ICD-10 Finland
Urticaria, unspecified
3.0
16.1
95
329
XW000
NOMESCO Finland
Bone marrow biopsy
3.1
16.1
91
304
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.1
16.0
89
296
L28
ICPC
Limited function/disability (L)
1.8
16.0
290
1704
N35.9
ICD-10 Finland
Urethral stricture, unspecified
9.5
15.9
32
34
K74.3
ICD-10 Finland
Primary biliary cirrhosis
9.5
15.9
32
34
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.5
15.9
75
221
A01AB09
ATC
miconazole; local oral
2.0
15.8
202
1045
ZXA00
NOMESCO Finland
Right side
1.6
15.8
513
3562
D07AC01
ATC
betamethasone; topical
1.5
15.8
652
4793
XQ860
NOMESCO Finland
Laser Doppler measurement/scan of capillary perfusion
+∞
15.6
15
*
K11.2
ICD-10 Finland
Sialoadenitis
3.1
15.4
84
276
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
15.3
322
1981
ELB10
NOMESCO Finland
Excision of minor salivary gland
16.2
15.2
24
15
L01AA01
ATC
cyclophosphamide; systemic
16.2
15.2
24
15
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
28.8
15.2
20
7
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
15.2
247
1398
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.1
15.1
171
840
G04BE03
ATC
sildenafil; oral
7.2
15.1
36
51
J01EA01
ATC
trimethoprim; systemic
1.5
15.0
547
3895
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.2
15.0
151
704
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
4.8
14.9
49
104
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
14.8
216
1172
R13
ICD-10 Finland
Dysphagia
2.3
14.6
133
591
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
12.0
14.6
26
22
N02AA05
ATC
oxycodone; systemic
1.8
14.5
252
1456
M01AX17
ATC
nimesulide; oral
1.6
14.5
473
3274
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
5.5
14.5
42
77
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
5.7
14.5
41
73
E000001
ATC
NA
1.6
14.5
416
2791
S01XA18
ATC
ciclosporin; ophthalmic
8.5
14.5
31
37
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
14.5
316
1966
M01AH05
ATC
etoricoxib; oral
1.4
14.4
1147
9592
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.3
14.4
73
228
J05AB01
ATC
aciclovir; systemic
1.6
14.3
435
2958
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.4
14.3
128
562
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.1
14.3
158
767
J05AB11
ATC
valaciclovir; oral
1.8
14.3
277
1661
A01
ICPC
Pain general/multiple sites
2.1
14.2
165
819
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
14.2
237
1352
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
4.5
14.2
50
114
R07.3
ICD-10 Finland
Other chest pain
2.0
14.1
193
1022
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.9
14.1
220
1226
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
14.1
483
3382
R76.0
ICD-10 Finland
Raised antibody titre
12.0
14.1
25
21
M01AB55
ATC
diclofenac, combinations; oral
2.2
14.1
142
661
K07.60
ICD-10 Finland
Snapping jaw
2.4
14.0
122
531
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
14.0
278
1678
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
11.0
14.0
26
24
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
14.0
419
2840
L95
ICPC
Osteoporosis
3.1
13.9
77
256
M48.0
ICD-10 Finland
Spinal stenosis
1.9
13.9
209
1147
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.3
13.9
136
625
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
13.8
848
6728
TNG10
NOMESCO Finland
Puncture of knee
5.8
13.8
38
66
B01AB05
ATC
enoxaparin; parenteral
1.5
13.7
566
4132
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
13.7
214
1191
R00.2
ICD-10 Finland
Palpitations
2.1
13.6
158
783
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
12.1
13.6
24
20
M35.4
ICD-10 Finland
Diffuse (eosinophilic) fasciitis
+∞
13.6
13
*
286
Kela drug reimbursment
Ciclosporin eye drop
+∞
13.6
13
*
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.7
13.5
95
367
M01AX01
ATC
nabumetone; oral
2.5
13.4
103
419
R03AC03
ATC
terbutaline; inhalant
1.7
13.4
287
1770
R53
ICD-10 Finland
Malaise and fatigue
1.6
13.4
392
2637
A02BX02
ATC
sucralfate; oral
2.6
13.4
98
386
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.7
13.3
275
1681
TAB00
NOMESCO Finland
Lumbar puncture
2.6
13.3
99
397
M05BA06
ATC
ibandronic acid; systemic
3.7
13.2
57
157
1XC02
NOMESCO Finland
NA
9.1
13.2
27
30
M01AE02
ATC
naproxen; oral, rectal
1.4
13.2
1110
9305
XF404
NOMESCO Finland
Ambulatory ECG
2.0
13.2
178
940
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
13.2
172
897
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.2
13.1
141
677
SPAT1229
SPAT
Assessment of need for aid
2.1
13.0
152
758
XF402
NOMESCO Finland
ECG with work load test
1.9
13.0
205
1144
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
2.3
13.0
120
538
R1250
NOMESCO Finland
Evaluation of functional capability
3.5
12.9
59
171
SAA04
NOMESCO Finland
Special inverstigation of mouth
2.3
12.9
116
511
A01AB04
ATC
amphotericin B; local oral
2.4
12.8
106
450
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.0
12.8
160
818
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.3
12.7
64
200
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
12.7
1359
11873
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.9
12.6
195
1082
JN4BD
NOMESCO Finland
Extensive body CT
1.9
12.6
200
1117
M01CB03
ATC
auranofin; oral
6.5
12.6
32
50
R42
ICD-10 Finland
Dizziness and giddiness
1.6
12.6
392
2673
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
2.0
12.6
155
788
G44.2
ICD-10 Finland
Tension-type headache
1.7
12.6
276
1715
G05.8*M32.1
ICD-10 Finland
Encephalitis in systemic lupus erythematosus
+∞
12.5
12
*
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
12.5
12
*
M35.2
ICD-10 Finland
Behçet disease
+∞
12.5
12
*
NJ3BG
NOMESCO Finland
MRI examination of extremities with high intensity magnet
17.4
12.5
19
11
SBB10
NOMESCO Finland
Teeth copy
2.2
12.5
127
595
M01CB01
ATC
sodium aurothiomalate; parenteral
4.4
12.5
44
101
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.6
12.5
90
355
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.1
12.4
134
646
K11.71
ICD-10 Finland
Xerostomy (dry mouth)
5.6
12.4
35
63
UJF92
NOMESCO Finland
Capsular endoscopy
3.6
12.4
55
156
I50.9
ICD-10 Finland
Heart failure, unspecified
1.9
12.3
200
1129
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.0
12.3
161
837
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
12.3
269
1669
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
12.3
243
1463
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
12.3
201
1137
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.7
12.3
303
1947
WX110
NOMESCO Finland
Local anesthesy
1.4
12.3
1327
11570
H02AB09
ATC
hydrocortisone; systemic
3.3
12.2
60
184
XA402
NOMESCO Finland
ENMG
3.2
12.2
64
206
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
12.1
373
2535
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
12.1
318
2075
N02AC04
ATC
dextropropoxyphene; oral
2.7
12.1
83
317
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
3.9
12.1
48
124
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
3.3
11.9
59
182
Z01.2
ICD-10 Finland
Dental examination
1.4
11.9
782
6229
ZXA05
NOMESCO Finland
Left side
1.5
11.8
461
3310
RT272
NOMESCO Finland
NA
9.7
11.7
23
24
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.0
11.6
45
114
M70.6
ICD-10 Finland
Trochanteric bursitis
1.7
11.5
249
1539
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
4.2
11.5
43
105
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
2.9
11.5
69
244
A03FA02
ATC
cisapride; oral, rectal
2.0
11.5
155
818
G72.9
ICD-10 Finland
Myopathy, unspecified
10.1
11.5
22
22
L20
ICPC
Joint symptom/complaint NOS
2.6
11.5
85
341
M30.0
ICD-10 Finland
Polyarteritis nodosa
+∞
11.5
11
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.5
11.5
87
353
M34
ICD-10 Finland
Systemic sclerosis
120.7
11.4
12
*
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.0
11.4
138
698
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
11.4
279
1784
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
11.4
345
2333
5BA08
NOMESCO Finland
NA
8.4
11.3
24
29
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
4.4
11.3
40
93
-1
NOMESCO Finland
NA
1.4
11.3
622
4784
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.7
11.2
75
283
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
11.1
676
5289
A02BA04
ATC
nizatidine; systemic
2.0
11.1
150
791
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
11.1
700
5514
J45.1
ICD-10 Finland
Nonallergic asthma
2.0
11.1
141
726
WX002
NOMESCO Finland
Sedation and analgesia
1.6
11.0
358
2460
R11
ICD-10 Finland
Nausea and vomiting
1.9
11.0
155
832
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
3.4
11.0
52
156
I27.0
ICD-10 Finland
Primary pulmonary hypertension
14.0
11.0
18
13
EL3AE
NOMESCO Finland
Salivary gland ultrasound examination
6.7
11.0
27
41
J01FA10
ATC
azithromycin; systemic
1.4
10.9
1148
9858
C02KX01
ATC
bosentan; oral
43.5
10.9
13
*
AA1AD
NOMESCO Finland
CT of head and brain
1.5
10.8
397
2802
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
4.4
10.8
38
88
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
10.8
431
3103
RT271
NOMESCO Finland
NA
17.9
10.7
16
9
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.3
10.7
102
464
AN1
HP
Coronary angiography
1.8
10.7
177
1005
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
10.7
228
1403
D02AE01
ATC
carbamide; topical
2.0
10.7
132
673
M06
ICD-10 Finland
Other rheumatoid arthritis
7.6
10.7
24
32
R05
ICD-10 Finland
Cough
1.5
10.7
361
2505
L17
ICPC
Foot/toe symptom/complaint
1.5
10.6
454
3315
R76.8
ICD-10 Finland
Other specified abnormal immunological findings in serum
60.3
10.6
12
*
J45.8
ICD-10 Finland
Mixed asthma
2.8
10.6
66
238
SPAT1255
SPAT
Intravenous administration of medicine
2.1
10.6
118
576
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
2.8
10.6
68
252
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.1
10.6
114
551
N03AE01
ATC
clonazepam; systemic
2.1
10.5
118
580
L04AB01
ATC
etanercept; parenteral
4.0
10.5
41
105
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
4.6
10.5
35
77
C02KX04
ATC
macitentan; oral
110.6
10.4
11
*
L87.1
ICD-10 Finland
Reactive perforating collagenosis
+∞
10.4
10
*
J99.1*M34.8
ICD-10 Finland
Respiratory disorders in systemic: sclerosis
+∞
10.4
10
*
J99.1*M35.0
ICD-10 Finland
Respiratory disorders in sicca syndrome [Sjögren]
+∞
10.4
10
*
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
10.4
10
*
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
+∞
10.4
10
*
7102B
ICD-9 Finland
Diffuse diseases of connective tissue, Sicca syndrome[SYNDROMA SICCUM SECUNDARIUM]
+∞
10.4
10
*
B02.9
ICD-10 Finland
Zoster without complication
2.1
10.4
115
562
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.6
10.3
314
2122
XG460
NOMESCO Finland
Short time oxymetry
4.2
10.3
38
92
XQ848
NOMESCO Finland
Dermatological photography
3.0
10.3
59
201
S97
ICPC
Chronic ulcer skin
2.3
10.3
97
440
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
10.3
904
7506
D70.89
ICD-10 Finland
Neutropenic splenomegaly
4.4
10.3
36
83
M25.9
ICD-10 Finland
Joint disorder, unspecified
4.7
10.3
34
74
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.7
10.3
43
117
K59.1
ICD-10 Finland
Functional diarrhoea
2.2
10.3
102
475
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.7
10.2
201
1207
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
10.2
527
3987
A12BA01
ATC
potassium chloride; oral
2.4
10.2
83
351
A41.9
ICD-10 Finland
Sepsis, unspecified
2.9
10.2
61
217
A05AA02
ATC
ursodeoxycholic acid; oral
3.5
10.1
46
134
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
10.1
1224
10686
D07AD01
ATC
clobetasol; topical
1.6
10.1
294
1964
UJF30
NOMESCO Finland
Ileoscopy through colon
1.8
10.1
181
1057
P01AB01
ATC
metronidazole; oral, rectal
1.4
10.1
783
6371
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.0
10.0
121
612
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
10.0
948
7958
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.7
10.0
65
243
R20.2
ICD-10 Finland
Paraesthesia of skin
2.0
10.0
129
672
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.7
9.9
205
1249
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
9.9
519
3934
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
2.7
9.9
66
248
UKC02
NOMESCO Finland
Cystoscopy
1.7
9.9
232
1467
L12
ICPC
Hand/finger symptom/complaint
1.6
9.9
262
1709
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.3
9.9
92
417
EBA10
NOMESCO Finland
Surgical removal of tooth
1.7
9.9
201
1222
SPAT1301
SPAT
No procedures
1.4
9.8
562
4329
WX203
NOMESCO Finland
Infraclavicular plexus blockade
3.0
9.8
54
182
I77.6
ICD-10 Finland
Arteritis, unspecified
20.1
9.8
14
7
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
9.8
180
1060
Z01.9
ICD-10 Finland
Special examination, unspecified
2.1
9.7
110
542
WZA90
NOMESCO Finland
Other doctors statement
1.5
9.7
410
2980
E000006
ATC
NA
1.9
9.7
150
831
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
2.4
9.7
77
323
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
6.2
9.7
25
41
T78.4
ICD-10 Finland
Allergy, unspecified
2.2
9.7
98
462
N05CF01
ATC
zopiclone; oral
1.4
9.6
574
4454
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
9.6
299
2027
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.8
9.6
164
940
M05BA01
ATC
etidronic acid; systemic
6.8
9.6
23
34
Z50.1
ICD-10 Finland
Other physical therapy
2.1
9.6
111
553
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
4.6
9.6
32
71
EB1BA
NOMESCO Finland
Extensive intraoral X-ray examination
11.4
9.6
17
15
S01GX01
ATC
cromoglicic acid; ophthalmic
1.5
9.5
391
2821
A28
ICPC
Limited function/disability NOS
1.6
9.5
233
1489
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.4
9.5
514
3915
M12.3
ICD-10 Finland
Palindromic rheumatism
15.1
9.5
15
10
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.8
9.5
149
833
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.2
9.5
96
449
R52.9
ICD-10 Finland
Pain, unspecified
1.8
9.5
158
902
H53.1
ICD-10 Finland
Subjective visual disturbances
2.0
9.5
117
599
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.9
9.5
141
774
M13.0
ICD-10 Finland
Polyarthritis, unspecified
4.0
9.4
36
91
XQ844
NOMESCO Finland
Other microscope or electron microscope examination
100.5
9.4
10
*
J01CA04
ATC
amoxicillin; systemic
1.4
9.4
1581
14465
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
30.2
9.4
12
*
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
4.6
9.4
31
68
J99.1*M32.1
ICD-10 Finland
Respiratory disorders in systemic: lupus erythematosus
+∞
9.4
9
*
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
5.3
9.4
27
51
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.3
9.3
83
368
J31.0
ICD-10 Finland
Chronic rhinitis
1.9
9.3
144
801
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.3
9.3
85
381
SHA04
NOMESCO Finland
Correction of physiology of bite - very demanding therapy visit
3.8
9.2
37
98
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.2
9.2
89
409
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
9.2
220
1399
6BA02
NOMESCO Finland
NA
13.7
9.2
15
11
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
9.1
221
1406
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.1
9.1
96
458
NDL52
NOMESCO Finland
Tenosynovectomy of hand
6.3
9.1
23
37
N06AX11
ATC
mirtazapine; oral
1.4
9.0
576
4515
K11.7
ICD-10 Finland
Disturbances of salivary secretion
36.8
9.0
11
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.8
9.0
36
95
J01FA09
ATC
clarithromycin; systemic
1.4
9.0
599
4728
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
3.4
9.0
41
121
K76.9
ICD-10 Finland
Liver disease, unspecified
3.5
9.0
40
116
R60.0
ICD-10 Finland
Localized oedema
1.7
8.9
192
1182
RT171
NOMESCO Finland
NA
18.7
8.9
13
7
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
3.6
8.9
38
106
M54.6
ICD-10 Finland
Pain in thoracic spine
1.9
8.9
121
642
RS221
NOMESCO Finland
NA
3.7
8.9
37
101
A46
ICD-10 Finland
Erysipelas
1.6
8.9
219
1402
ZX108
NOMESCO Finland
Inhalation
6.1
8.9
23
38
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.7
8.9
60
228
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.1
8.9
47
155
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
4.8
8.9
28
59
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
8.0
8.8
19
24
SPAT1263
SPAT
Sampling
1.3
8.8
771
6352
B07.9
ICD-10 Finland
Verruca simplex
2.5
8.7
67
276
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
8.7
129
705
M84.3
ICD-10 Finland
Stress fracture, not elsewhere classified
4.4
8.7
30
69
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
2.6
8.7
60
233
Z71.8
ICD-10 Finland
Other specified counselling
1.4
8.7
423
3151
SPAT1153
SPAT
Removal of sutures
1.4
8.7
552
4317
WW200
NOMESCO Finland
Immunization
2.8
8.7
52
186
ND1AE
NOMESCO Finland
Wrist ultrasound examination
7.7
8.6
19
25
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
5.0
8.6
26
52
R01AD09
ATC
mometasone; nasal
1.3
8.6
852
7144
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
8.6
477
3643
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.9
8.6
51
181
R01AD08
ATC
fluticasone; nasal
1.4
8.5
544
4256
M79.9
ICD-10 Finland
Soft tissue disorder, unspecified
4.4
8.5
29
66
SPAT1231
SPAT
Assessment of adjustments needed in living environment
3.4
8.5
40
121
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.4
8.5
593
4708
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
8.5
410
3051
A01AB10
ATC
natamycin; local oral
2.6
8.5
59
231
NH3AE
NOMESCO Finland
Feet ultrasound examination
6.4
8.5
21
33
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
8.5
973
8331
L94.9
ICD-10 Finland
Localized connective tissue disorder, unspecified
90.4
8.4
9
*
GDG10
NOMESCO Finland
Bilateral transplantation of lung
90.4
8.4
9
*
H03AA01
ATC
levothyroxine sodium; systemic
1.4
8.4
485
3727
D07AB08
ATC
desonide; topical
1.6
8.4
195
1231
L84
ICD-10 Finland
Corns and callosities
2.4
8.4
67
280
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.5
8.3
280
1933
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.8
8.3
151
884
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
8.3
205
1313
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
8.6
8.3
17
20
K11.70
ICD-10 Finland
Hypoptyalism
5.3
8.3
24
46
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
8.3
314
2223
N06AX16
ATC
venlafaxine; oral
1.5
8.2
259
1759
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.6
8.2
204
1306
C08DB01
ATC
diltiazem; oral
2.2
8.2
83
392
7290A
ICD-9 Finland
Other disorders of soft tissues, Rheumatism, unspecified and fibrositis
6.5
8.2
20
31
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
7.6
8.2
18
24
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
5.4
8.1
23
43
L01
ICPC
Neck symptom/complaint
1.5
8.1
249
1683
SPAT1254
SPAT
Administration of medicine
1.6
8.1
240
1610
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.1
8.0
88
428
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
8.0
1055
9186
UJD02
NOMESCO Finland
Gastroscopy
2.1
8.0
88
431
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.2
8.0
78
361
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
7.3
8.0
18
25
ZXA10
NOMESCO Finland
Bilateral
1.5
7.9
322
2315
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
2.5
7.9
59
241
B01AA03
ATC
warfarin; systemic
1.5
7.9
286
2005
M03BX02
ATC
tizanidine; oral
1.3
7.9
1189
10535
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.7
7.9
50
185
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
5.4
7.8
22
41
C07AB02
ATC
metoprolol; systemic
1.4
7.8
339
2466
D01AE16
ATC
amorolfine; topical
1.6
7.8
206
1341
L01CB
ATC
Podophyllotoxin derivatives
10.8
7.8
14
13
TND10
NOMESCO Finland
Joint puncture, wrist or finger joint
9.4
7.8
15
16
R03BA01
ATC
beclometasone; inhalant
1.5
7.7
258
1779
L30.8
ICD-10 Finland
Other specified dermatitis
2.7
7.7
50
188
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.5
7.7
242
1644
78890
ICD-8 Finland
Other general symptoms, Hypersedimentatio
45.1
7.7
9
*
4430A
ICD-9 Finland
Other peripheral vascular disease, Raynaud's syndrome
45.1
7.7
9
*
7199L
ICD-9 Finland
Other and unspecified disorder of joint, Unspecified disorder of joint[MB ARTICULI NUD,USEAT NIVELET]
15.1
7.7
12
8
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.6
7.7
180
1136
SBA00
NOMESCO Finland
Microbiological examinations
2.6
7.7
51
196
N30.0
ICD-10 Finland
Acute cystitis
1.5
7.6
261
1810
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
2.7
7.6
49
183
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.7
7.6
145
863
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
2.2
7.6
71
324
H19.3
ICD-10 Finland
Keratitis and keratoconjunctivitis in other diseases classified elsewhere
18.4
7.6
11
6
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
7.6
414
3145
R03BA08
ATC
ciclesonide; inhalant
1.7
7.6
163
1007
N35.0
ICD-10 Finland
Post-traumatic urethral stricture
25.1
7.6
10
*
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
7.6
724
6011
XA800
NOMESCO Finland
Neuropsychological investigation
2.2
7.6
73
337
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
7.6
541
4301
M45
ICD-10 Finland
Ankylosing spondylitis
2.9
7.6
44
155
K22.4
ICD-10 Finland
Dyskinesia of oesophagus
5.2
7.5
22
43
G47.3
ICD-10 Finland
Sleep apnoea
1.4
7.5
317
2295
R03BB04
ATC
tiotropium bromide; inhalant
1.7
7.5
149
897
C03DA01
ATC
spironolactone; oral
1.6
7.5
170
1067
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
4.0
7.5
28
71
J47
ICD-10 Finland
Bronchiectasis
3.1
7.5
39
129
R01AD12
ATC
fluticasone furoate; nasal
1.3
7.4
545
4343
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.1
7.4
77
367
D02AX
ATC
Other emollients and protectives
2.2
7.4
68
309
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.8
7.4
129
746
XF600
NOMESCO Finland
Bloodpressure measurement
1.9
7.4
109
598
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.0
7.4
86
430
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
4.1
7.4
27
67
L94.0
ICD-10 Finland
Localized scleroderma [morphea]
6.0
7.4
19
32
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
2.4
7.4
58
243
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.8
7.4
120
682
R4190
NOMESCO Finland
Nutritional therapy
2.4
7.4
59
251
S01KA02
ATC
hypromellose; ophthalmic
2.9
7.4
43
152
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
7.4
1008
8777
NHQ40
NOMESCO Finland
Amputation of toe
3.8
7.4
29
77
L29.9
ICD-10 Finland
Pruritus, unspecified
2.6
7.3
49
189
XG466
NOMESCO Finland
Sleep oxymetry
2.4
7.3
56
233
RJ420
NOMESCO Finland
NA
8.4
7.3
15
18
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.8
7.3
128
743
N16.4*M35.0
ICD-10 Finland
Sjögren's syndrome with renal tubulo-interstitial disorders
+∞
7.3
7
*
G73.7*M32.1
ICD-10 Finland
Myopathy in systemic lupus erythematosus
+∞
7.3
7
*
M30.1
ICD-10 Finland
Polyarteritis with lung involvement [Churg-Strauss]
+∞
7.3
7
*
J99.1*M33.2
ICD-10 Finland
Respiratory disorders in polymyositis
+∞
7.3
7
*
RT274
NOMESCO Finland
NA
10.9
7.3
13
12
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
6.8
7.3
17
25
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
4.9
7.3
22
45
M54.8
ICD-10 Finland
Other dorsalgia
2.2
7.3
71
330
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.5
7.2
238
1636
N07AA02
ATC
pyridostigmine; systemic
6.3
7.2
18
29
M50.3
ICD-10 Finland
Other cervical disc degeneration
2.6
7.2
50
194
A06AD11
ATC
lactulose; oral
1.5
7.2
223
1509
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
2.7
7.2
46
171
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.9
7.2
103
559
NB2AT
NOMESCO Finland
Intra artrial injection of shoulder with ultrasound guidance
4.1
7.2
26
64
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.5
7.2
299
2157
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.9
7.2
107
590
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
7.2
461
3595
A07EA06
ATC
budesonide; oral, local oral
2.2
7.2
68
313
E000007
ATC
NA
1.9
7.2
105
576
K29.3
ICD-10 Finland
Chronic superficial gastritis
2.3
7.1
62
272
SPAT1325
SPAT
Vaccination
1.3
7.1
584
4731
M79.3
ICD-10 Finland
Panniculitis, unspecified
7.9
7.1
15
19
S22
ICPC
Nail symptom/complaint
1.9
7.1
97
520
K02.1
ICD-10 Finland
Caries of dentine
1.3
7.1
1029
9012
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.1
7.1
79
388
N06AB04
ATC
citalopram; systemic
1.4
7.1
397
3028
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.9
7.1
106
585
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
3.0
7.1
37
123
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.8
7.0
117
669
R05
ICPC
Cough
1.4
7.0
390
2965
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.7
7.0
45
167
R68.2
ICD-10 Finland
Dry mouth, unspecified
4.3
7.0
24
56
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
3.6
7.0
29
81
SXC03
NOMESCO Finland
Other oral or dental procedure
3.7
7.0
28
76
7806A
ICD-9 Finland
General symptoms, Pyrexia of unknown origin
4.5
7.0
23
52
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.5
6.9
250
1753
R35
ICD-10 Finland
Polyuria
1.9
6.9
93
493
R63.4
ICD-10 Finland
Abnormal weight loss
2.4
6.9
55
232
N05CD07
ATC
temazepam; oral
1.5
6.9
208
1400
NG1DA
NOMESCO Finland
X-ray of knees
2.9
6.9
40
141
K75.4
ICD-10 Finland
Autoimmune hepatitis
13.8
6.9
11
8
R03DC03
ATC
montelukast; oral
1.4
6.9
302
2203
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.6
6.9
48
188
XG405
NOMESCO Finland
Education on PEF monitoring
3.0
6.9
36
120
J96.1
ICD-10 Finland
Chronic respiratory failure
3.2
6.9
34
109
ND1AA
NOMESCO Finland
Wrist X-ray examination
1.8
6.8
115
659
XKD00
NOMESCO Finland
Uroflowmetry
1.6
6.8
168
1075
NK6PA
NOMESCO Finland
Measurement of bone density from one location with X-ray
8.3
6.8
14
17
M62.9
ICD-10 Finland
Disorder of muscle, unspecified
11.0
6.8
12
11
L95.8
ICD-10 Finland
Other vasculitis limited to skin
11.0
6.8
12
11
N35.8
ICD-10 Finland
Other urethral stricture
11.0
6.8
12
11
ND2AE
NOMESCO Finland
Hand and fingers ultrasound examination
9.3
6.8
13
14
H15.1
ICD-10 Finland
Episcleritis
3.3
6.8
32
99
78880
ICD-8 Finland
Other general symptoms, Pyrexia of unknown origin
5.3
6.8
19
36
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
5.3
6.8
19
36
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
40.2
6.8
8
*
M05.2
ICD-10 Finland
Rheumatoid vasculitis
40.2
6.8
8
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.4
6.7
55
237
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.1
6.7
70
336
M02AA07
ATC
piroxicam; topical
1.3
6.7
663
5503
TQW80
NOMESCO Finland
Local dermatologic skincare
2.5
6.7
51
211
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
2.2
6.7
67
314
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
6.7
414
3206
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
2.0
6.7
83
427
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
2.7
6.7
43
160
L03
ICPC
Low back symptom/complaint
1.4
6.7
421
3270
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.8
6.7
107
606
WX892
NOMESCO Finland
Monitored bed care
1.8
6.7
110
625
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.5
6.7
197
1322
Z94.2
ICD-10 Finland
Lung transplant status
22.6
6.7
9
*
H16.0
ICD-10 Finland
Corneal ulcer
2.0
6.7
81
416
R03BB01
ATC
ipratropium bromide; inhalant
2.2
6.7
65
305
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
6.4
6.6
16
25
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
6.4
6.6
16
25
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.1
6.6
71
345
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
12.3
6.6
11
9
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.0
6.6
82
424
ZZA00
NOMESCO Finland
Split skin graft
2.4
6.5
50
208
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
10.0
6.5
12
12
F45.9
ICD-10 Finland
Somatoform disorder, unspecified
10.0
6.5
12
12
K92.1
ICD-10 Finland
Melaena
2.1
6.5
71
349
N03AF01
ATC
carbamazepine; oral, rectal
1.9
6.5
88
470
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
2.7
6.5
42
158
KMAK
NOMESCO Finland
NA
1.3
6.5
956
8350
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
5.0
6.5
19
38
B01AC04
ATC
clopidogrel; oral
1.5
6.5
206
1405
TQW99
NOMESCO Finland
Other minor procedure on skin
2.0
6.4
79
406
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
2.8
6.4
39
143
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
70.1
6.4
7
*
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.4
6.4
323
2412
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
6.4
517
4168
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
2.8
6.4
38
137
K90.9
ICD-10 Finland
Intestinal malabsorption, unspecified
7.4
6.4
14
19
L93.1
ICD-10 Finland
Subacute cutaneous lupus erythematosus
14.3
6.4
10
7
RF120
NOMESCO Finland
NA
3.9
6.4
24
62
M13.8
ICD-10 Finland
Other specified arthritis
3.8
6.4
25
67
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.8
6.4
104
594
H16.9
ICD-10 Finland
Keratitis, unspecified
3.0
6.4
33
110
R06AX22
ATC
ebastine; oral
1.4
6.3
320
2394
C09CA06
ATC
candesartan; oral
1.4
6.3
373
2865
F45.0
ICD-10 Finland
Somatization disorder
5.5
6.3
17
31
GD2SN
NOMESCO Finland
Lung ventilation SPECT
5.5
6.3
17
31
RT350
NOMESCO Finland
NA
11.0
6.3
11
10
N04BC05
ATC
pramipexole; oral
1.7
6.3
124
747
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
6.3
417
3267
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
2.1
6.3
69
341
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
2.0
6.3
73
367
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
6.3
129
790
N08.5*M31.7
ICD-10 Finland
Glomerular disease states in microscopic polyangiitis
+∞
6.3
6
*
N08.5*M31.0
ICD-10 Finland
Glomerular disorders in Goodpasture's syndrome
+∞
6.3
6
*
J99.1*M33.9
ICD-10 Finland
Respiratory disorders in dermatopolymyositis
+∞
6.3
6
*
M31.0
ICD-10 Finland
Hypersensitivity angiitis
+∞
6.3
6
*
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.8
6.2
110
643
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
2.3
6.2
56
251
G03DB01
ATC
dydrogesterone; oral
1.4
6.2
276
2016
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
7.0
6.2
14
20
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
7.0
6.2
14
20
XCK00
NOMESCO Finland
Perimetry
1.7
6.2
115
682
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
1.9
6.2
89
485
D06BX01
ATC
metronidazole; topical
1.5
6.2
197
1343
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
6.2
928
8111
D07AC13
ATC
mometasone; topical
1.3
6.2
507
4097
NG4AA
NOMESCO Finland
Lower leg X-ray examination
2.3
6.2
53
233
A06AC51
ATC
ispaghula, combinations; systemic
1.8
6.2
93
517
J98.1
ICD-10 Finland
Pulmonary collapse
5.3
6.1
17
32
SFA40
NOMESCO Finland
Replacement of krone of tooth
1.4
6.1
347
2644
J01FA01
ATC
erythromycin; systemic
1.4
6.1
256
1847
C01DA14
ATC
isosorbide mononitrate; oral
1.5
6.1
202
1389
J01DA06
ATC
[U] cefuroxime; systemic
1.4
6.1
256
1850
R69
ICD-10 Finland
Unknown and unspecified causes of morbidity
2.8
6.1
36
130
M05.3
ICD-10 Finland
Rheumatoid arthritis with involvement of other organs and systems
12.6
6.1
10
8
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
2.7
6.1
38
143
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
2.9
6.1
33
114
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
10.0
6.0
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
397
174
27.44
307.65
1.7
1.1
67.9
50.4
u/ml
—
52
5
865
459
29.83
307.65
3.4
1.2
1.1
1.2
g/l
15.13
841
431
533
334
20.55
307.65
1.7
1.1
60.3
18.1
u/ml
4.90
125
24
659
399
22.86
307.65
1.8
1.1
19.5
3.4
u/ml
6.48
249
53
673
438
21.42
307.65
1.8
1.1
33.1
14.3
u/ml
1.14
96
21
1208
2461
9.35
307.65
2.2
1.3
1104.4
390.7
titre
30.33
660
458
291
175
18.93
307.65
3.1
1.1
35.9
25.6
iu/ml
—
52
5
655
391
23.14
307.65
1.8
1.1
9.9
2.1
u/ml
2.18
155
31
254
108
26.35
307.65
1.4
1.1
—
—
—
0
0
686
657
14.53
307.65
1.7
1.2
4.2
1.0
u/ml
2.32
51
53
865
438
31.29
307.65
3.4
1.2
0.2
0.2
g/l
20.85
839
412
619
1296
6.19
295.13
3.6
2.6
11.5
10.4
g/l
4.94
587
1169
1815
9251
5.80
280.36
12.0
5.4
0.5
0.6
e9/l
1.14
1728
7992
1819
9292
5.82
280.07
12.1
5.4
0.0
0.0
e9/l
1.28
1730
8025
1838
9655
5.75
267.77
12.5
5.6
0.2
0.2
e9/l
3.67
1763
8469
1822
9544
5.61
265.24
12.2
5.5
1.7
1.9
e9/l
12.68
1754
8422
163
54
32.44
250.59
1.2
1.0
—
—
—
0
0
391
621
7.40
242.72
1.5
1.2
17.1
9.8
u/ml
—
10
5
231
185
13.79
240.07
1.8
1.2
—
—
—
0
0
1628
8424
4.30
224.42
12.4
5.6
0.7
0.7
%
1.70
1589
7833
1887
10872
5.36
223.89
14.8
8.7
3.8
4.0
e9/l
3.47
1794
9494
1342
6140
3.90
220.87
10.6
5.5
—
—
—
0
0
1646
8690
4.25
217.69
12.4
5.5
2.8
2.8
%
0.28
1610
8071
1649
8741
4.24
216.19
12.9
5.8
9.0
8.4
%
15.23
1608
8169
475
1023
5.61
215.15
1.9
1.8
1.5
1.4
g/l
0.27
446
927
1657
8892
4.20
211.38
12.1
5.4
58.0
56.8
%
3.86
1616
8310
1204
5263
3.74
209.35
3.3
2.0
136.0
205.1
u/l
2.31
1156
4950
1659
9014
4.12
205.21
12.6
5.6
27.3
28.6
%
6.01
1620
8387
174
113
16.59
202.82
1.7
1.1
40.2
24.0
u/ml
—
19
5
102
10
106.75
198.08
1.7
1.6
—
—
—
0
0
149
94
16.89
176.02
2.0
1.2
5.7
5.7
u/l
0.01
133
80
868
3438
3.47
168.62
1.5
1.3
41.8
33.9
iu/ml
0.66
361
1070
212
265
8.72
160.27
2.9
1.5
0.9
0.7
g/l
1.32
172
197
826
3289
3.38
157.29
1.4
1.2
8.1
12.1
u/ml
1.25
327
1302
2015
14119
4.80
139.57
10.7
3.7
14.8
11.9
mm/h
13.01
1975
13085
1421
8128
3.00
137.44
3.0
2.2
80.8
77.8
nmol/l
3.73
1348
7342
154
160
10.25
133.80
2.4
1.4
2.8
2.9
g/l
0.19
124
108
154
160
10.25
133.80
2.4
1.4
7.6
6.7
g/l
0.84
122
110
154
160
10.25
133.80
2.4
1.4
0.4
0.4
g/l
0.00
124
109
155
166
9.95
131.70
2.4
1.4
—
—
—
0
0
185
279
7.13
118.32
1.5
1.2
4.2
4.7
u/ml
0.15
95
110
169
234
7.72
116.68
1.7
1.1
—
—
—
0
0
1989
14443
4.05
115.87
12.8
7.2
74.7
77.6
u/l
2.18
1962
13578
1468
9061
2.76
113.81
7.6
6.3
1.2
1.2
mmol/l
1.12
1293
7676
951
4743
2.73
113.44
3.7
2.9
944.8
1190.5
ng/l
1.69
854
3999
1848
12926
3.31
112.25
8.2
4.2
—
—
—
0
0
869
4189
2.74
110.24
8.4
4.2
—
—
—
0
0
798
3760
2.73
104.94
1.8
1.4
2.5
2.3
g/l
1.89
572
2285
1461
9213
2.64
104.71
6.0
3.6
0.0
0.0
estimate
0.50
279
1669
72
29
25.61
102.87
1.2
1.0
—
—
—
0
0
72
29
25.61
102.87
1.2
1.0
—
—
—
0
0
72
29
25.61
102.87
1.2
1.0
—
—
—
0
0
143
189
8.01
102.61
2.4
2.3
—
—
—
0
0
404
1310
3.53
102.40
2.1
3.0
68.0
66.7
g/l
2.30
379
1191
1467
9350
2.61
101.45
6.1
3.6
0.0
0.0
estimate
1.32
283
1663
359
1083
3.75
101.43
1.8
2.7
—
—
—
0
0
1336
8192
2.53
99.63
6.7
5.6
1.2
1.2
mmol/l
1.15
1259
7406
997
5380
2.52
97.52
4.5
3.8
7.4
7.4
ph
1.24
166
997
1445
9259
2.54
96.88
7.9
4.8
0.0
0.0
estimate
0.38
287
1692
419
1519
3.16
87.70
5.6
3.7
0.8
1.0
%
0.82
133
387
840
4365
2.47
86.96
5.5
3.6
—
—
—
0
0
1178
7147
2.35
85.17
5.3
3.4
—
5.8
—
0
5
216
522
4.47
82.18
2.6
2.4
193.0
813.3
ug/l
0.95
200
489
396
1447
3.10
81.36
5.7
3.8
0.0
0.2
%
5.21
124
353
1073
6384
2.29
79.59
5.6
3.4
64.7
97.2
e6/l
1.22
795
4369
371
1360
3.07
75.45
5.9
3.8
0.0
0.6
%
0.97
103
298
715
3682
2.37
73.21
3.6
2.4
4.3
7.2
e6/l
7.87
654
3209
195
477
4.38
72.87
1.6
2.1
10.6
11.4
mg/l
0.69
180
438
1270
8336
2.19
71.13
15.5
8.7
0.0
0.0
e9/l
0.49
1131
6805
1216
7906
2.16
69.03
5.9
4.6
35.3
35.8
g/l
2.57
1159
7376
213
579
3.96
68.98
1.7
2.7
11.9
10.2
g/l
3.72
195
491
365
1392
2.93
68.79
5.5
3.6
0.4
0.7
%
2.78
91
280
906
5323
2.17
66.00
4.6
3.0
77.4
75.9
e6/l
0.01
760
4006
563
2759
2.38
63.23
2.7
2.3
12.1
13.3
umol/l
3.77
530
2547
77
87
9.13
62.50
1.2
1.1
12.3
8.3
u/ml
—
7
11
184
483
4.06
62.42
1.3
1.2
715.7
947.1
titre
0.22
14
14
497
2324
2.46
61.82
2.8
2.4
20.8
22.7
%
2.64
430
1995
835
4863
2.13
61.16
10.1
6.4
—
—
—
0
0
84
109
7.96
61.00
1.2
1.1
1.1
1.0
ratio
1.25
31
47
65
60
11.12
60.96
1.2
1.2
0.2
0.4
g/l
—
6
5
180
482
3.97
59.35
1.3
1.2
90.0
94.7
titre
0.06
13
30
184
501
3.91
59.27
1.8
2.6
37.4
38.1
g/l
0.75
172
433
409
1782
2.58
58.90
2.0
2.1
366.8
374.9
nmol/l
0.23
387
1623
821
4810
2.11
58.67
4.3
2.8
—
—
—
0
0
582
2985
2.28
58.16
3.3
2.5
0.8
1.2
e6/l
3.08
389
1635
786
4542
2.12
58.15
3.0
2.4
2990.0
5382.5
umol/l
1.15
710
3935
512
2504
2.35
57.10
2.7
2.3
2.3
2.4
g/l
1.14
486
2317
83
115
7.45
56.95
1.3
1.1
187.3
147.1
titre
0.19
26
21
95
153
6.44
56.70
2.1
2.4
1.1
1.1
e9/l
0.02
57
92
793
4634
2.09
56.65
2.9
2.1
2.9
3.0
mg/l
0.15
706
3951
826
4901
2.08
56.63
4.5
2.9
0.2
0.4
e6/l
6.04
679
3643
319
1291
2.71
52.97
2.3
2.4
36.9
24.0
au/ml
0.63
18
82
348
1472
2.61
52.89
5.5
3.5
—
—
—
0
0
325
1336
2.67
52.29
3.4
2.9
150.2
180.4
ng/l
0.76
307
1203
298
1177
2.76
51.83
1.3
1.3
25.7
43.0
au/ml
1.41
11
56
491
2481
2.25
49.98
2.7
2.0
—
—
—
0
0
750
4483
2.00
48.87
5.6
4.1
—
—
—
0
0
426
2051
2.33
48.52
1.6
1.5
—
—
—
0
0
144
394
3.83
45.91
1.8
1.7
10096.7
11516.8
e6/l
0.18
112
291
1321
9654
1.88
45.75
7.1
6.1
9.7
10.7
umol/l
5.18
1276
9148
69
104
6.81
43.84
2.0
2.4
429.2
528.5
e6/l
0.47
58
83
380
1825
2.30
43.14
3.7
2.6
1.7
1.8
%
1.95
358
1623
66
98
6.91
42.51
2.0
2.5
0.2
0.2
e9/l
0.35
58
82
1200
8635
1.83
42.34
3.6
2.8
113.2
102.2
ug/l
1.03
1135
8042
199
705
3.00
42.04
2.3
1.8
1.4
1.5
g/l
0.79
182
614
72
119
6.22
41.86
2.0
2.1
12.5
13.1
%
0.13
33
48
1587
12480
1.90
41.72
6.4
4.4
3933.1
2343.7
e6/l
0.35
31
159
149
445
3.51
41.70
1.5
1.3
—
—
—
0
0
413
2093
2.19
40.98
2.2
1.7
—
—
—
0
0
49
54
9.25
40.46
1.3
1.1
—
—
—
0
0
775
4944
1.86
39.84
7.1
3.9
0.0
0.0
estimate
0.19
288
1669
665
4041
1.91
39.76
6.5
4.0
1.0
1.0
kg/l
1.88
88
591
213
810
2.80
39.46
1.3
1.2
—
—
—
0
0
124
342
3.78
39.04
1.3
1.8
—
—
—
0
0
74
137
5.55
38.27
2.3
2.1
54.2
42.1
%
1.70
13
17
48
56
8.73
37.93
1.1
1.1
—
—
—
0
0
66
111
6.09
37.71
2.2
2.6
587.7
687.6
e6/l
0.47
30
45
123
347
3.69
37.47
3.9
3.5
59.7
57.7
%
0.96
123
347
1051
7468
1.76
36.87
2.1
1.9
99.0
96.9
pmol/l
0.71
552
3753
703
4438
1.85
36.78
1.4
1.3
2.1
1.5
u/ml
0.47
185
1186
150
495
3.17
35.72
1.9
4.0
36.1
53.5
mg/l
0.71
123
408
664
4160
1.84
35.36
1.6
1.5
20.0
21.2
nmol/l
1.53
588
3567
957
6678
1.75
35.32
4.4
3.4
27.2
40.1
ng/l
1.23
654
4219
289
1340
2.33
35.21
1.4
1.4
—
—
—
0
0
149
494
3.16
35.20
2.0
4.0
46.5
66.8
mg/l
0.68
123
405
406
2181
2.05
34.05
1.9
1.4
—
—
—
0
0
144
480
3.14
33.70
2.0
4.0
1.3
1.8
ratio
0.55
13
39
2121
18998
2.77
33.63
27.0
12.8
18.0
22.0
mg/l
10.70
1881
14876
411
2230
2.03
33.49
5.8
5.3
1.0
1.0
mmol/l
0.31
389
2066
927
6483
1.73
33.42
3.5
3.4
2.3
2.4
mmol/l
2.61
824
5727
41
46
9.06
33.38
1.1
1.0
—
—
—
0
0
168
616
2.87
33.22
2.5
2.0
1.7
2.1
ug/l
0.24
146
534
548
3305
1.87
32.54
1.7
1.8
—
—
—
0
0
484
2804
1.92
32.53
1.6
1.6
—
—
—
0
0
46
63
7.43
31.84
1.3
1.2
—
—
—
0
0
965
6923
1.69
30.97
10.8
8.0
1.2
1.2
inr
0.21
269
2038
483
2851
1.88
30.44
4.2
3.3
0.8
0.8
mmol/l
0.53
457
2661
327
1687
2.10
30.35
2.8
2.2
0.2
0.2
g/l
0.07
304
1581
278
1351
2.21
30.06
2.7
2.6
68.0
71.7
e9/l
0.99
205
1022
93
254
3.77
29.69
2.5
3.4
1.5
1.5
%
0.01
76
203
101
294
3.55
29.35
1.4
1.6
—
—
—
0
0
656
4305
1.74
28.79
2.0
1.8
1.1
1.1
mg/l
0.07
516
3270
521
3202
1.81
28.63
1.8
1.7
1224.4
1184.9
nmol/l
0.46
435
2407
264
1286
2.19
28.31
1.4
1.3
213.4
185.6
u/ml
0.22
240
1176
1337
10611
1.63
27.56
5.9
4.4
6.4
6.6
mmol/l
4.58
1276
9886
542
3422
1.77
26.99
4.0
2.6
509.4
534.6
mosm/kgh2o
2.11
478
2910
461
2783
1.82
26.66
3.8
2.6
2.1
3.4
e6/l
3.46
271
1443
817
5779
1.65
26.59
2.9
2.5
62.0
56.7
u/l
1.09
775
5331
410
2410
1.86
25.76
2.2
2.2
121.8
119.3
ug/g
0.04
325
1895
821
5878
1.62
25.09
3.7
3.1
—
—
—
0
0
107
358
3.09
24.87
2.0
4.3
—
—
—
0
0
267
1373
2.07
24.75
8.0
7.2
8.9
9.0
mmol/l
0.12
251
1313
194
888
2.30
24.09
2.1
1.9
—
—
—
0
0
99
326
3.13
23.65
1.4
1.3
—
—
—
0
0
32
41
7.90
23.42
1.3
1.2
—
—
—
0
0
101
348
2.99
22.32
2.3
2.2
125.5
129.7
g/l
0.77
59
255
287
1569
1.95
22.31
1.2
1.2
—
—
—
0
0
428
2655
1.75
22.17
1.3
1.2
—
—
—
0
0
91
298
3.14
21.95
1.3
1.3
135.5
113.9
u/ml
0.36
15
57
179
824
2.27
21.90
1.1
1.1
1.8
0.9
u/ml
—
7
8
424
2633
1.75
21.85
2.4
2.1
29.8
29.4
s
0.76
415
2558
331
1912
1.86
21.71
7.9
7.4
1.2
1.1
mmol/l
0.10
266
1492
49
105
4.75
21.52
2.4
2.8
44.8
43.5
%
0.16
16
32
515
3386
1.67
21.49
4.7
3.5
273.2
319.1
ng/l
0.25
390
2454
91
302
3.10
21.47
1.3
1.2
304.8
274.2
u/ml
0.22
59
186
331
1919
1.85
21.45
8.0
7.4
5.0
5.1
kpa
0.75
313
1835
356
2114
1.81
21.33
24.0
23.1
1.3
1.3
inr
0.01
71
292
330
1919
1.84
21.16
8.0
7.4
12.2
12.8
kpa
1.21
312
1835
249
1335
1.97
20.42
3.5
2.9
3.7
4.0
e9/l
1.22
194
1079
178
842
2.21
20.38
3.5
2.6
0.1
0.3
e6/l
2.02
171
808
295
1681
1.87
20.12
8.5
7.9
95.5
95.9
%
0.64
281
1624
199
994
2.10
19.82
4.9
3.4
5.2
5.2
kpa
0.14
190
929
128
532
2.49
19.70
1.3
1.2
—
—
—
0
0
37
67
5.60
19.62
2.2
2.0
—
—
—
0
0
71
214
3.39
19.61
3.1
2.7
—
—
—
0
0
1756
15425
1.61
19.43
4.9
4.3
14.8
14.7
pmol/l
1.83
1667
14188
69
207
3.41
19.20
3.1
2.7
—
—
—
0
0
64
183
3.57
19.16
2.7
3.9
—
—
—
0
0
58
155
3.81
19.16
2.3
3.1
59.4
57.5
%
0.22
36
107
514
3481
1.62
18.75
2.7
3.0
2.4
2.5
mmol/l
0.33
460
3079
193
983
2.05
18.23
4.9
3.4
7.4
7.4
ph
1.54
30
121
55
147
3.81
18.17
1.1
1.2
—
—
—
0
0
686
5001
1.53
18.03
5.6
3.2
—
—
—
0
0
54
144
3.82
17.90
1.8
1.5
32.0
37.8
%
0.54
33
90
77
261
3.02
17.55
1.5
1.5
—
—
—
0
0
1016
8065
1.47
17.44
2.3
2.1
—
—
—
0
0
247
1391
1.87
17.39
2.5
2.3
11.0
6.5
ug/l
0.68
210
1215
252
1430
1.86
17.32
3.5
3.5
80.3
80.2
ng/l
0.01
232
1229
125
546
2.36
17.26
1.1
1.1
6.6
4.4
u/ml
0.32
14
73
150
708
2.20
17.25
1.1
1.0
—
—
—
0
0
345
2151
1.71
17.21
2.9
2.5
6.3
7.5
umol/l
1.00
301
1858
226
1241
1.91
17.19
3.4
2.9
—
—
—
0
0
95
365
2.67
17.19
4.7
2.9
24.6
25.2
mmol/l
0.59
86
322
1962
17891
1.71
16.88
6.0
5.0
1.9
2.0
mu/l
0.65
1873
16536
50
134
3.79
16.48
1.1
1.1
—
—
—
0
0
61
187
3.32
16.44
1.7
1.6
54.0
59.7
%
0.46
32
117
74
259
2.92
15.96
4.1
2.7
—
—
—
0
0
638
4685
1.50
15.82
5.3
3.7
93.7
93.5
%
0.06
620
4567
297
1821
1.73
15.66
4.2
4.0
—
—
—
0
0
141
683
2.13
15.20
2.4
2.1
22.3
20.9
s
1.08
121
599
264
1581
1.76
15.11
9.1
8.3
119.0
120.4
g/l
0.56
251
1523
250
1476
1.78
15.03
7.4
6.6
1.2
1.3
mmol/l
0.92
243
1428
84
333
2.58
14.32
1.1
1.2
—
—
—
0
0
327
2117
1.64
13.96
8.7
6.5
104.4
104.4
mmol/l
0.01
315
2073
104
462
2.31
13.86
2.4
2.1
—
—
—
0
0
233
1381
1.77
13.79
8.5
8.0
—
—
—
0
0
51
159
3.26
13.43
1.5
1.4
4639.4
100561.5
e6/l
1.24
38
118
245
1488
1.72
13.30
3.6
3.5
5.9
5.8
kpa
0.72
237
1451
73
281
2.65
13.22
1.4
1.6
—
—
—
0
0
242
1471
1.72
13.09
3.7
3.5
2.4
2.0
mmol/l
1.10
207
1205
141
730
1.99
12.72
4.6
3.5
—
—
—
0
0
41
115
3.61
12.71
1.2
1.1
0.4
6.2
nmol/l
0.64
11
21
18
24
7.55
12.70
1.1
1.1
—
—
—
0
0
162
881
1.90
12.66
9.6
9.2
24.1
24.4
mmol/l
0.62
148
832
674
5183
1.43
12.63
4.5
3.6
—
—
—
0
0
218
1315
1.73
12.11
1.7
1.4
—
—
—
0
0
185
1070
1.79
11.88
5.4
5.3
—
—
—
0
0
180
1035
1.80
11.79
7.7
7.1
25.2
24.5
mmol/l
1.28
168
960
1488
13144
1.38
11.68
4.8
3.5
—
—
—
0
0
50
169
3.00
11.55
1.4
2.1
—
—
—
0
0
22
41
5.41
11.35
2.0
2.1
130.7
143.3
e6/l
0.08
14
18
33
87
3.83
11.20
1.3
1.8
—
—
—
0
0
238
1507
1.65
11.01
1.3
1.2
150.5
150.1
iu/ml
0.01
80
579
20
35
5.76
11.01
7.3
4.7
—
—
—
0
0
1751
15960
1.42
10.99
29.4
15.8
13.9
13.7
%
10.65
1738
15621
25
54
4.67
10.94
1.2
1.3
—
—
—
0
0
276
1817
1.59
10.89
1.8
1.4
—
—
—
0
0
24
51
4.75
10.71
1.6
1.4
44.5
43.0
%
0.06
19
44
68
285
2.43
10.39
1.1
1.0
3.4
2.2
u/ml
0.46
19
134
68
286
2.42
10.32
1.2
1.1
—
—
—
0
0
2123
20217
1.77
10.28
20.2
10.0
24.5
24.9
u/l
0.76
2104
19551
260
1712
1.59
10.23
1.5
1.4
—
—
—
0
0
1050
8901
1.33
10.13
4.9
3.9
—
—
—
0
0
2053
19402
1.61
9.97
23.6
14.6
139.4
139.7
mmol/l
6.43
2022
18915
36
110
3.31
9.86
1.3
1.2
—
—
—
0
0
109
566
1.97
9.80
1.3
1.4
315.6
300.7
ug/g
0.32
58
309
545
6917
0.72
9.78
2.8
2.7
—
—
—
0
0
15
22
6.86
9.73
1.3
1.1
—
—
—
0
0
68
295
2.35
9.65
1.0
1.1
—
—
—
0
0
138
779
1.82
9.63
3.6
3.9
24.7
24.2
mmol/l
1.20
130
708
41
139
2.99
9.47
1.2
1.2
35.7
38.9
mg/l
0.25
35
116
85
410
2.11
9.35
1.2
1.3
3.7
3.7
mmol/l
0.18
77
389
43
151
2.88
9.34
1.1
1.2
—
—
—
0
0
22
49
4.52
9.30
1.9
2.5
143.5
38.8
au/ml
—
5
6
14
20
7.04
9.29
1.4
1.2
—
—
—
0
0
2054
19463
1.58
9.27
23.8
14.7
3.9
3.9
mmol/l
1.75
2020
18942
39
131
3.01
9.16
1.1
1.1
226.4
243.9
mg/l
0.27
33
115
507
3891
1.39
9.15
1.7
1.7
461.3
34516166.4
pmol/l
3.73
442
3242
84
409
2.09
9.03
1.4
1.5
269.1
1417.5
e6/l
0.95
72
328
47
178
2.68
8.89
1.3
1.3
32.3
33.7
g/l
0.27
39
156
155
932
1.71
8.72
4.1
3.2
—
—
—
0
0
38
130
2.96
8.66
1.4
1.2
—
—
—
0
0
83
409
2.07
8.66
1.3
1.4
8.5
22.4
e6/l
0.91
67
308
29
84
3.48
8.65
1.8
1.8
—
—
—
0
0
162
989
1.69
8.62
7.4
6.7
25.0
25.0
mmol/l
0.01
162
984
26
70
3.75
8.61
1.0
1.1
301.3
187.7
iu/ml
0.35
26
70
68
312
2.22
8.51
1.4
1.3
57.2
61.5
mmol/l
0.40
58
257
192
1232
1.61
8.41
3.2
2.8
4.8
4.6
kpa
0.28
185
1198
44
166
2.68
8.40
1.3
1.3
4780.3
2578.9
e6/l
0.50
25
112
168
1051
1.65
8.15
10.5
8.7
93.8
94.1
%
0.26
168
1046
570
4534
1.34
8.07
2.8
2.2
—
—
—
0
0
100
541
1.89
8.02
3.2
3.3
—
—
—
0
0
38
136
2.82
8.02
1.3
1.4
—
—
—
0
0
64
294
2.21
8.00
1.1
1.1
—
—
—
0
0
12
17
7.09
7.99
1.3
1.4
5.0
6.1
mmol/l
—
6
12
70
334
2.13
7.97
2.2
3.2
30.2
36.1
umol/l
1.45
65
289
145
883
1.69
7.81
12.3
10.3
—
—
—
0
0
21
52
4.07
7.80
2.5
2.4
—
—
—
0
0
219
1475
1.54
7.78
4.2
3.5
1.2
1.2
mmol/l
0.27
206
1276
39
145
2.72
7.68
1.2
1.3
116926.9
111693.6
e6/l
0.02
16
78
21
53
3.99
7.61
1.5
1.6
—
—
—
0
0
48
201
2.42
7.44
1.4
1.3
—
—
—
0
0
252
1775
1.47
7.22
2.4
2.3
38.9
37.3
u/l
0.09
217
1508
66
321
2.09
7.18
1.7
1.6
—
—
—
0
0
94
521
1.84
7.03
6.4
7.5
1.4
1.3
mmol/l
0.65
84
453
105
603
1.78
6.99
2.3
3.3
0.4
0.3
g/l
0.41
34
228
47
202
2.35
6.90
2.1
1.3
—
—
—
0
0
47
202
2.35
6.90
2.1
1.3
—
—
—
0
0
47
202
2.35
6.90
2.1
1.3
—
—
—
0
0
47
202
2.35
6.90
2.1
1.3
—
—
—
0
0
292
2140
1.42
6.76
1.3
1.3
—
—
—
0
0
151
965
1.60
6.76
2.3
2.4
—
—
—
0
0
713
5989
1.28
6.53
2.9
2.3
—
—
—
0
0
172
1146
1.54
6.44
1.3
1.2
—
—
—
0
0
46
203
2.29
6.39
1.7
1.6
—
—
—
0
0
1385
12592
1.26
6.35
4.0
3.0
55.1
44.5
u/l
2.30
1312
11770
64
325
2.00
6.24
3.5
2.4
16.0
16.3
%
0.27
40
157
13
26
5.02
6.22
1.5
2.2
—
—
—
0
0
194
1343
1.49
6.07
2.9
3.3
4.3
4.5
pmol/l
1.48
179
1194
17
44
3.89
5.98
1.0
1.0
—
—
—
0
0
35
141
2.51
5.95
1.2
1.3
—
—
—
0
0
30
113
2.68
5.83
1.4
1.1
—
—
—
0
0
38
161
2.38
5.81
1.0
1.1
—
—
—
0
0
58
293
2.01
5.77
1.1
1.2
—
—
—
0
0
23
75
3.09
5.77
1.7
1.3
2.3
4.6
%
—
7
15
106
647
1.67
5.73
5.2
3.6
24.7
25.0
mmol/l
0.37
98
600
19
55
3.48
5.73
2.1
1.2
—
—
—
0
0
101
609
1.69
5.72
1.3
1.2
—
—
—
0
0
47
220
2.16
5.71
1.0
1.2
—
—
—
0
0
43
195
2.23
5.64
2.4
2.5
—
—
—
0
0
41
183
2.26
5.59
1.2
1.2
—
—
—
0
0
19
58
3.29
5.30
35.5
29.3
7.0
7.2
ug/l
0.16
19
49
63
340
1.88
5.20
5.2
3.6
—
—
—
0
0
67
374
1.82
4.99
1.3
1.5
—
—
—
0
0
16
46
3.50
4.89
1.2
1.1
—
—
—
0
0
27
106
2.57
4.88
1.1
1.2
—
—
—
0
0
104
662
1.60
4.81
4.8
4.1
—
—
—
0
0
639
5494
1.23
4.46
3.4
3.1
6.7
7.1
mmol/l
1.56
553
4646
598
5108
1.23
4.44
3.5
3.2
741.5
351.3
mg/l
0.77
387
3092
130
1862
0.68
4.40
1.3
1.3
—
—
—
0
0
34
156
2.20
4.40
1.3
1.5
—
—
—
0
0
102
662
1.57
4.38
6.3
6.2
1.6
1.6
%
0.53
96
619
9
12
7.52
4.35
1.2
1.0
—
—
—
0
0
17
56
3.05
4.24
1.4
1.2
37.3
38.1
g/l
—
7
30
113
758
1.52
4.19
3.7
2.9
25.9
25.4
mmol/l
0.61
108
738
81
504
1.63
4.15
1.2
1.2
—
—
—
0
0
22
85
2.60
4.14
2.2
3.3
7.5
7.4
ph
1.16
13
26
14
43
3.27
3.90
1.0
1.2
—
—
—
0
0
100
665
1.53
3.89
6.4
6.3
0.9
0.9
%
0.35
93
621
84
539
1.58
3.82
1.5
1.9
116.1
4.5
iu/l
0.49
28
196
37
187
1.99
3.78
1.1
1.6
—
—
—
0
0
80
509
1.59
3.78
4.7
3.5
3.9
3.8
mmol/l
0.30
75
479
7
8
8.77
3.77
1.0
1.0
—
—
—
0
0
8
12
6.68
3.67
1.1
1.0
—
—
—
0
0
8
12
6.68
3.67
1.0
1.2
—
—
—
0
0
56
328
1.73
3.64
3.1
3.1
0.7
0.8
nmol/l
0.99
45
255
1804
17258
1.22
3.59
5.8
5.5
38.6
39.3
mmol/mol
3.49
1719
16002
81
1218
0.65
3.54
1.6
1.4
—
—
—
0
0
8
13
6.17
3.50
1.5
1.2
85.8
79.2
umol/l
—
8
13
34
172
1.99
3.49
1.1
1.1
—
—
—
0
0
34
172
1.99
3.49
1.4
1.2
—
—
—
0
0
614
5376
1.19
3.42
4.3
3.8
15.0
8.5
mg/mmol
1.45
401
3274
30
147
2.05
3.36
1.1
1.5
12.9
11.7
umol/l
0.45
30
138
17
65
2.63
3.30
1.5
1.8
—
—
—
0
0
23
103
2.25
3.22
1.1
1.7
9.4
8.2
ug/l
0.12
18
89
14
49
2.87
3.19
1.3
1.1
—
—
—
0
0
8
15
5.35
3.19
1.1
1.9
—
—
—
0
0
7
11
6.38
3.18
1.1
1.1
—
—
—
0
0
12
39
3.09
3.09
1.2
1.1
—
—
—
0
0
6
8
7.52
3.05
1.2
1.0
—
—
—
0
0
108
769
1.42
3.05
1.6
1.7
—
—
—
0
0
18
74
2.44
3.04
1.2
1.1
—
—
—
0
0
59
370
1.61
3.02
7.7
9.1
10.4
11.2
mmol/l
1.03
53
332
59
371
1.61
2.99
7.7
9.1
104.4
105.0
mmol/l
0.30
53
333
19
81
2.36
2.98
1.1
1.1
1333.5
1627.3
miu/ml
0.67
19
81
14
52
2.70
2.89
1.4
2.2
8.6
10.3
mg/l
0.44
14
42
9
22
4.10
2.88
1.0
1.0
—
—
—
0
0
17
70
2.44
2.88
1.4
1.2
—
—
—
0
0
35
193
1.83
2.84
3.1
3.3
—
—
—
0
0
1701
16290
1.18
2.84
32.5
16.7
329.8
331.7
g/l
13.71
1693
16176
67
442
1.53
2.79
1.3
1.4
11.9
12.2
u/l
0.06
61
356
10
31
3.24
2.77
1.0
1.2
478.5
45.7
ug/l
—
5
15
24
118
2.04
2.71
1.3
1.2
—
—
—
0
0
20
93
2.16
2.61
4.5
2.9
—
—
—
0
0
18
80
2.26
2.60
1.4
1.2
—
—
—
0
0
18
80
2.26
2.60
1.8
2.1
17.3
19.0
ug/l
0.19
18
68
15
62
2.43
2.54
1.2
1.1
—
—
—
0
0
10
33
3.04
2.52
1.9
1.6
—
—
—
0
0
52
333
1.57
2.49
1.1
1.3
—
—
—
0
0
54
352
1.55
2.41
3.4
2.6
—
—
—
0
0
10
34
2.95
2.41
2.3
1.4
—
—
—
0
0
33
190
1.75
2.37
1.3
1.6
—
—
—
0
0
2034
19865
1.23
2.37
20.8
12.2
—
—
—
0
0
38
228
1.68
2.37
3.3
2.0
11.4
21.9
u/ml
0.26
38
216
33
191
1.74
2.34
1.8
1.4
276.6
277.6
mosm/kgh2o
0.09
28
146
55
363
1.53
2.33
6.2
3.9
2.7
2.7
mmol/l
0.01
40
248
6
13
4.62
2.27
1.0
1.0
—
—
—
0
0
6
13
4.62
2.27
1.0
1.1
—
—
—
0
0
194
1579
1.25
2.25
7.4
3.9
—
—
—
0
0
8
24
3.34
2.18
1.0
1.0
—
—
—
0
0
42
270
1.57
2.03
1.3
1.2
74.6
23.9
u/l
0.63
36
231
11
44
2.51
2.01
3.2
2.8
—
—
—
0
0
8
27
2.97
1.93
1.1
3.3
—
—
—
0
0
17
85
2.01
1.90
5.1
3.0
—
—
—
0
0
49
333
1.48
1.87
1.6
1.4
14.1
27.1
u/l
4.19
44
277
8
28
2.86
1.86
1.1
1.2
71.1
87.5
ng/l
—
8
28
16
79
2.03
1.85
4.4
2.8
—
—
—
0
0
50
343
1.47
1.83
1.5
1.4
0.3
0.3
nmol/l
0.03
41
258
21
116
1.82
1.78
1.0
1.1
—
—
—
0
0
13
60
2.17
1.77
3.3
2.1
—
—
—
0
0
20
109
1.84
1.77
1.0
1.0
—
—
—
0
0
34
216
1.58
1.76
1.5
1.6
—
—
—
0
0
94
723
1.31
1.76
2.0
2.1
11.3
11.6
nmol/l
0.11
82
642
62
448
1.39
1.73
5.7
3.6
7.4
7.4
ph
0.01
55
359
1887
18406
1.15
1.72
4.6
4.4
5.7
5.9
mmol/l
5.24
1771
16860
2144
21141
1.25
1.71
37.4
19.2
91.5
90.9
fl
5.57
2133
20866
2143
21132
1.25
1.69
37.6
19.3
260.5
258.5
e9/l
0.70
2119
20631
2144
21144
1.25
1.68
37.3
19.2
30.2
30.2
pg
0.04
2133
20866
2144
21145
1.25
1.67
37.5
19.3
4.4
4.5
e12/l
13.90
2115
20590
26
157
1.66
1.65
1.3
1.1
337.2
395.2
nmol/l
0.75
18
144
2144
21148
1.25
1.65
37.6
19.3
6.5
6.6
e9/l
1.34
2115
20584
11
226
0.48
1.65
1.1
1.1
—
—
—
0
0
2144
21152
1.24
1.62
37.8
19.4
131.0
133.8
g/l
17.92
2135
20875
26
159
1.64
1.59
1.2
1.2
0.2
0.5
u/ml
0.59
19
65
48
339
1.42
1.55
1.3
1.2
—
—
—
0
0
5
15
3.34
1.52
1.0
2.3
—
—
—
0
0
7
27
2.60
1.51
1.3
3.4
—
—
—
0
0
16
86
1.87
1.50
3.9
2.5
—
—
—
0
0
25
154
1.63
1.50
1.2
1.4
19.2
12.4
mmol/l
—
8
40
32
211
1.52
1.46
2.7
4.5
19.6
96.8
u/ml
1.44
11
61
16
87
1.84
1.45
1.3
1.6
—
—
—
0
0
282
2485
1.15
1.45
1.3
1.3
—
—
—
0
0
82
639
1.29
1.44
3.2
3.6
17.5
2244.8
u/ml
0.83
69
554
14
73
1.92
1.43
2.0
2.2
53.9
51.7
umol/l
—
8
55
142
1181
1.22
1.43
1.4
1.3
33.0
30.7
iu/l
0.32
121
1010
203
1747
1.18
1.41
1.5
1.6
—
—
—
0
0
23
141
1.64
1.41
2.4
2.1
—
—
—
0
0
9
40
2.25
1.40
1.2
1.3
0.7
4.4
%
—
9
34
5
17
2.94
1.36
1.0
1.1
—
—
—
0
0
49
358
1.38
1.34
2.4
2.9
—
—
—
0
0
46
337
1.37
1.25
1.1
1.1
6.0
4.1
u/ml
0.31
27
163
14
77
1.82
1.25
3.7
2.9
—
—
—
0
0
35
245
1.44
1.23
1.7
1.4
49.8
43.1
mu/l
0.18
30
223
17
100
1.71
1.23
1.1
1.4
134.5
133.5
nmol/l
0.03
17
100
27
395
0.68
1.20
1.5
1.4
—
—
—
0
0
27
392
0.68
1.16
1.5
1.4
—
—
—
0
0
11
58
1.90
1.12
1.4
1.8
—
—
—
0
0
80
646
1.25
1.11
1.6
1.3
137.5
223.4
miu/ml
1.86
28
324
13
73
1.79
1.10
1.5
1.3
—
—
—
0
0
5
21
2.38
1.09
20.2
9.4
5.5
6.0
mmol/l
—
5
21
42
312
1.35
1.08
1.1
1.1
—
—
—
0
0
7
32
2.19
1.08
1.0
1.0
—
—
—
0
0
91
751
1.22
1.05
2.2
2.1
5199.4
4245.6
u/l
0.08
26
310
211
1870
1.14
1.05
3.0
4.1
3.1
23.6
ug/l
3.46
160
1492
29
405
0.71
1.03
1.6
1.5
—
—
—
0
0
9
47
1.92
1.02
1.1
2.1
—
—
—
0
0
12
68
1.77
1.00
1.5
3.1
65.7
182.9
umol/l
—
6
41
5
109
0.46
1.00
22.0
12.0
649.2
847.2
nmol/l
—
5
104
43
326
1.33
0.99
1.1
1.1
0.2
1.3
u/ml
1.79
20
133
9
50
1.80
0.96
1.2
1.3
—
—
—
0
0
12
69
1.74
0.96
15.5
11.3
—
—
—
0
0
31
227
1.37
0.90
1.2
1.4
316.4
307.8
pmol/l
0.05
26
181
50
394
1.28
0.89
4.4
3.7
28.9
24.7
mg/l
0.38
37
249
6
29
2.07
0.89
1.3
1.1
—
—
—
0
0
6
30
2.00
0.87
4.5
9.7
—
—
—
0
0
13
80
1.63
0.84
4.2
2.2
9.2
9.7
mmol/l
—
6
64
40
310
1.30
0.82
1.1
1.1
—
—
—
0
0
18
261
0.69
0.82
1.2
1.2
—
—
—
0
0
17
113
1.51
0.82
1.2
1.2
—
—
—
0
0
107
1236
0.86
0.81
1.8
1.7
—
—
—
0
0
67
555
1.21
0.80
2.2
2.4
—
—
—
0
0
26
191
1.37
0.77
1.2
1.6
—
—
—
0
0
5
24
2.09
0.74
2.0
1.0
—
—
—
0
0
7
38
1.84
0.73
1.3
2.4
21.5
19.2
umol/l
—
7
38
47
379
1.25
0.73
1.1
1.1
2.3
1.4
u/ml
0.22
21
148
1778
17500
1.07
0.72
25.6
14.0
38.9
39.4
%
1.71
1264
12897
7
40
1.75
0.71
1.4
1.6
—
—
—
0
0
20
143
1.40
0.70
1.7
2.2
1.3
2.5
u/field
—
9
60
9
58
1.55
0.69
2.3
1.9
—
—
—
0
0
14
93
1.51
0.69
1.1
1.4
—
73.8
%
—
0
11
7
42
1.67
0.68
1.3
1.1
—
—
—
0
0
26
198
1.32
0.64
1.5
1.2
—
—
—
0
0
11
164
0.67
0.61
1.1
1.2
—
—
—
0
0
8
52
1.54
0.59
1.1
1.7
—
—
—
0
0
10
64
1.56
0.58
1.9
1.1
—
16.8
%
—
0
5
21
158
1.33
0.57
2.9
2.6
15.2
25.6
mg/l
0.51
16
114
35
283
1.24
0.56
2.0
1.7
53.3
42.5
nmol/l
0.87
35
274
8
55
1.46
0.56
1.4
1.3
—
—
—
0
0
78
683
1.15
0.54
1.8
1.6
282.1
316.2
mu/l
0.58
70
615
19
142
1.34
0.54
1.6
2.0
15.9
19.1
nmol/l
1.47
19
134
6
38
1.58
0.54
4.5
3.3
—
—
—
0
0
1899
18789
1.07
0.52
4.5
4.3
4.6
4.8
mmol/l
9.53
1804
17496
23
293
0.78
0.52
1.3
2.2
—
—
—
0
0
48
408
1.18
0.49
2.4
2.4
35.5
102.3
ug/min
2.38
30
250
37
307
1.21
0.49
1.1
1.1
0.6
2.5
u/ml
1.91
12
72
1887
18682
1.06
0.47
4.5
4.2
1.5
1.5
mmol/l
1.05
1784
17304
16
120
1.34
0.46
1.0
1.0
—
—
—
0
0
1819
17998
1.05
0.45
4.1
3.8
1.2
1.3
mmol/l
2.66
1716
16570
10
69
1.45
0.44
1.6
1.5
15.0
14.1
pmol/l
—
10
57
27
220
1.23
0.43
1.1
1.1
0.1
0.4
u/ml
—
9
51
5
31
1.61
0.43
1.2
1.5
—
—
—
0
0
8
56
1.43
0.42
1.5
2.1
—
—
—
0
0
26
212
1.23
0.42
2.2
2.1
—
—
—
0
0
55
626
0.88
0.41
1.3
1.7
—
—
—
0
0
29
240
1.21
0.41
1.1
1.1
2.9
4.2
u/ml
0.41
16
91
51
582
0.87
0.40
1.3
1.8
—
—
—
0
0
5
34
1.47
0.40
1.8
1.9
—
—
—
0
0
5
34
1.47
0.40
1.0
1.4
—
—
—
0
0
5
35
1.43
0.39
1.2
1.2
—
—
—
0
0
30
252
1.19
0.38
1.4
1.3
—
—
—
0
0
29
243
1.20
0.37
1.6
1.2
—
—
nmol/l
—
0
0
18
143
1.26
0.37
1.8
2.0
11.4
10.8
%
0.34
18
143
56
629
0.89
0.36
1.3
1.7
—
—
—
0
0
6
43
1.40
0.35
1.0
1.0
—
—
—
0
0
55
616
0.89
0.34
1.3
1.7
—
—
—
0
0
10
133
0.75
0.33
1.1
1.1
—
—
—
0
0
56
624
0.89
0.33
1.3
1.7
—
—
—
0
0
38
434
0.87
0.32
1.3
1.3
—
—
—
0
0
1923
19109
1.04
0.28
4.9
4.7
2.7
2.8
mmol/l
11.10
1819
17687
44
489
0.90
0.26
1.3
1.7
—
—
—
0
0
525
5119
1.03
0.26
1.6
1.7
1.3
1.4
mmol/l
0.24
466
4346
150
1577
0.95
0.24
2.9
3.0
0.7
0.8
ug/l
0.53
105
1019
141
1341
1.05
0.23
1.2
1.2
—
—
—
0
0
86
805
1.07
0.23
1.1
1.1
—
—
—
0
0
18
153
1.18
0.22
1.2
1.1
—
—
—
0
0
5
41
1.22
0.22
1.0
1.0
—
—
—
0
0
5
42
1.19
0.21
1.0
1.0
—
—
—
0
0
280
2715
1.04
0.20
4.4
4.8
2.2
2.7
ug/l
0.45
247
2411
14
166
0.84
0.20
1.9
1.6
—
—
—
0
0
9
112
0.80
0.20
1.2
1.4
5.5
5.9
mmol/l
—
9
107
6
50
1.20
0.19
1.8
1.6
—
—
—
0
0
12
99
1.21
0.19
1.0
1.0
—
0.3
—
0
16
208
2150
0.96
0.18
1.8
1.7
—
—
—
0
0
12
100
1.20
0.18
1.3
1.4
1.5
1.2
nmol/l
0.28
12
81
197
1906
1.04
0.17
1.5
1.4
—
—
—
0
0
29
263
1.10
0.16
1.1
1.1
6.8
3.0
u/ml
0.34
14
95
27
244
1.11
0.16
2.3
2.1
5.4
5.8
umol/l
0.09
19
170
13
111
1.17
0.15
3.8
3.5
—
—
—
0
0
12
102
1.18
0.15
1.7
1.4
—
—
—
0
0
15
131
1.15
0.14
3.8
6.4
—
—
—
0
0
21
189
1.11
0.13
2.8
2.7
—
—
—
0
0
17
152
1.12
0.12
1.9
1.4
0.8
1.0
g/l
1.01
17
152
33
308
1.07
0.11
1.1
1.1
72.3
1830.9
iu/ml
—
6
72
21
193
1.09
0.10
3.8
2.4
—
—
—
0
0
57
594
0.96
0.09
1.2
1.3
—
—
—
0
0
22
236
0.93
0.08
1.1
1.4
2.9
4.1
ug/l
0.42
16
207
32
338
0.95
0.08
2.2
1.8
—
—
—
0
0
46
441
1.04
0.07
5.5
4.1
—
—
—
0
0
525
5211
1.01
0.06
1.5
1.5
—
—
—
0
0
14
133
1.05
0.01
1.6
1.3
—
1.5
—
0
8
41
417
0.98
0.01
1.7
2.5
—
—
—
0
0
10
94
1.06
0.01
1.1
1.6
—
—
—
0
0
26
265
0.98
0.00
3.5
5.4
366.7
366.6
umol/l
0.00
20
228
62
624
0.99
0.00
16.5
9.3
—
—
—
0
0
48
475
1.01
0.00
1.1
1.1
—
—
—
0
0
36
364
0.99
0.00
2.1
2.2
0.8
0.8
nmol/l
0.42
29
302
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
164.6
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
90.3
—
0
6
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
108.8
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
0.00
1.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_CONNECTNAS and mortality.

Females

Parameter HR [95% CI] p-value
M13_CONNECTNAS 1.701 [1.54, 1.88] < 0.001
Birth year 0.995 [0.99, 1.0] 0.266

During the follow-up period (1.1.1998 — 31.12.2019), 1412 out of 7588 females with M13_CONNECTNAS died.

Males

Parameter HR [95% CI] p-value
M13_CONNECTNAS 1.857 [1.6, 2.16] < 0.001
Birth year 0.988 [0.98, 1.0] 0.012

During the follow-up period (1.1.1998 — 31.12.2019), 678 out of 2013 males with M13_CONNECTNAS died.

Mortality risk

Mortality risk for people of age

years, who have M13_CONNECTNAS.

N-year risk Females Males
1 0.156% 0.352%
5 0.931% 1.948%
10 2.497% 5.225%
15 4.892% 9.977%
20 8.538% 16.941%

Relationships between endpoints

Index endpoint: M13_CONNECTNAS – Other specified/unspecified systemic involvement of connective tissue

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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