Major anomalies of jaw size

K11_MAJOR_ANOMALI_JAW_SIZE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K07.0
  • Hospital discharge: ICD-10 K07.0
  • Hospital discharge: ICD-9 5240A
  • Hospital discharge: ICD-8 524
  • Cause of death: ICD-10 K07.0
  • Cause of death: ICD-9 5240A
  • Cause of death: ICD-8 524

3 out of 7 registries used, show all original rules.

1067

4. Check minimum number of events

None

1067

5. Include endpoints

None

1067

6. Filter based on genotype QC (FinnGen only)

1027

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13353 6803 6524
Only index persons 12168 6223 5945
Unadjusted period prevalence (%)
Whole population 0.19 0.19 0.18
Only index persons 0.23 0.23 0.23
Median age at first event (years)
Whole population 16.68 17.52 15.76
Only index persons 17.56 18.45 16.63

-FinnGen-

Key figures

All Female Male
Number of individuals 1027 609 418
Unadjusted period prevalence (%) 0.21 0.22 0.19
Median age at first event (years) 27.61 30.23 23.78

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1067
Matched controls
10670
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
83.2
307.7
186
27
K07.13
ICD-10 Finland
Retrognaty, mandibular
30.2
302.5
208
85
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
+∞
270.7
248
*
SBB10
NOMESCO Finland
Dental impressions
8.5
225.4
369
624
EEC05
NOMESCO Finland
Le Fort I osteotomy
94.2
210.3
110
13
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
12.3
203.7
223
224
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
14.7
203.4
196
161
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
11.8
201.6
228
240
K07.14
ICD-10 Finland
Retrognaty, maxillary
82.9
184.1
98
13
5240A
ICD-9 Finland
Dentofacial anomalies, including malocclusion, Major anomalies of jaw size
+∞
182.7
170
*
EB1MA
NOMESCO Finland
Cephalometry with X-ray
11.9
181.9
202
206
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
11.2
179.4
209
228
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
9.1
176.9
249
347
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
11.8
170.0
188
190
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
63.4
147.7
82
14
SJC10
NOMESCO Finland
Orthodontic band in one tooth
10.8
145.8
170
184
52430
ICD-8 Finland
Dento-facial anomalies including malocclusion, Anomalies of tooth position
+∞
145.2
136
*
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
15.5
142.2
129
94
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
+∞
136.4
128
*
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
9.1
133.5
178
229
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
37.4
132.7
83
24
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
+∞
129.9
122
*
SAA04
NOMESCO Finland
Special examination of mouth
7.0
129.0
227
399
K07.10
ICD-10 Finland
Asymmetry of jaw
55.1
126.3
72
14
K07.24
ICD-10 Finland
Open bite
16.6
120.2
104
69
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
8.4
119.8
171
238
4344
FHL
Osteotomy and shaping of the lower jaw (jaw deformities)
591.2
109.9
107
*
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
8.0
105.1
154
220
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
9.6
102.2
127
148
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
9.2
94.1
121
147
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
8.6
94.0
128
167
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
50.6
91.4
53
11
K07.23
ICD-10 Finland
Deep bite
7.2
87.2
140
220
K07.0
ICD-10 Finland
Major anomalies of jaw size
+∞
81.3
77
*
K07.00
ICD-10 Finland
Macrognatia (hyperplasia) of the upper jaw
+∞
80.2
76
*
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
39.5
79.7
49
13
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
7.5
79.5
121
179
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
101.2
77.2
84
9
K07.60
ICD-10 Finland
Snapping jaw
5.6
76.4
160
326
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
7.2
74.1
117
180
K07.09
ICD-10 Finland
Anomaly in the size of the jaws UNS
+∞
73.8
70
*
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
7.1
72.8
116
180
EBB10
NOMESCO Finland
Insertion of dental implant
15.0
72.1
65
46
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
5.1
69.4
162
362
EBB15
NOMESCO Finland
Insertion of dental implant abutment
22.8
62.6
46
21
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
15.1
62.6
56
39
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
8.1
62.3
87
116
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
4.2
60.2
180
488
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
3.6
57.6
228
750
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
9.0
53.8
68
80
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
102.2
53.4
58
6
4347
FHL
Osteotomy of the upper jaw
189.4
52.4
54
*
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
5.0
50.4
117
258
4343
FHL
Lower jaw open osteotomy
182.0
50.3
52
*
SPC20
NOMESCO Finland
Implant borne crown
18.0
49.1
40
23
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
5.0
47.7
108
233
K07.08
ICD-10 Finland
Other specified anomaly in the size of the cores
+∞
46.2
44
*
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
11.4
45.3
48
44
52400
ICD-8 Finland
Dento-facial anomalies including malocclusion, Major anomalies of jaw size
+∞
43.0
41
*
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
5.0
42.8
96
205
4305
FHL
Tooth extraction by cutting
14.4
42.7
39
28
K07.4
ICD-10 Finland
Malocclusion, unspecified
7.0
41.6
65
98
K00.00
ICD-10 Finland
Hypodontia
8.3
40.4
54
68
SAA03
NOMESCO Finland
Extended examination of mouth
2.3
39.3
580
3620
SXC05
NOMESCO Finland
Other oral or dental procedure
3.3
38.8
164
554
WZC00
NOMESCO Finland
Treatment plan or consultation
2.3
38.8
488
2843
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
10.9
38.6
42
40
SXC03
NOMESCO Finland
Other oral or dental procedure
11.5
37.3
39
35
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
7.4
34.6
51
72
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
46.1
33.0
40
9
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
9.6
32.8
39
42
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
3.9
32.7
102
281
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
4.0
31.1
94
253
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
45.1
28.8
35
8
EDC30
NOMESCO Finland
Genioplasty
106.4
28.8
31
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.9
28.4
146
549
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
8.0
27.8
38
49
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
6.5
26.7
44
70
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
5.7
25.7
49
90
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
4.8
25.0
57
123
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
10.2
24.8
28
28
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
3.1
24.5
110
382
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
8.2
24.0
32
40
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
22.7
514
3513
9165
FHL
Removal of osteosynthesis material
6.1
22.3
39
66
K07.05
ICD-10 Finland
Micrognatia (hypoplasia) of both jaws
+∞
21.9
21
*
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
63.9
21.9
25
*
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
6.7
21.8
35
54
5241A
ICD-9 Finland
Dentofacial anomalies, including malocclusion, Anomalies of relationship of jaw to cranial base
44.3
21.5
26
6
ZXA10
NOMESCO Finland
Bilateral
2.2
21.2
199
989
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
33.3
20.2
26
8
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
6.7
20.1
32
49
52410
ICD-8 Finland
Dento-facial anomalies including malocclusion, Anomalies of jaw-cranial base relationships
+∞
18.8
18
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.7
18.4
103
403
K07.62
ICD-10 Finland
Habitual dislocation of the jaw joint
7.9
17.5
24
31
G50.1
ICD-10 Finland
Atypical facial pain
5.5
16.9
33
62
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
14.5
16.4
27
19
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
3.6
16.2
55
160
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
3.4
16.1
58
176
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
21.3
16.0
23
11
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
4.6
15.5
37
83
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
3.9
15.2
45
119
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
3.2
14.4
59
194
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.1
14.1
149
770
SJB30
NOMESCO Finland
Extraoral traction arrangements and operation instruction, removable appliance
5.3
14.0
28
54
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
12.9
13.9
24
19
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
14.9
13.6
22
15
52411, ,
ICD-8 Finland
+∞
13.6
13
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
13.4
377
2632
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
13.4
344
2345
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
13.2
141
730
EB1WA, ,
NOMESCO Finland
10.6
12.8
24
23
K07.9
ICD-10 Finland
Dentofacial anomaly, unspecified
131.5
12.5
13
*
K01.0
ICD-10 Finland
Embedded teeth
3.6
12.4
40
113
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
23.2
11.6
16
7
4839
FHL
Other measure in this category
+∞
11.5
11
*
K07
ICD-10 Finland
Dentofacial anomalies [including malocclusion]
8.4
11.3
24
29
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
11.1
808
6965
P01AB01
ATC
metronidazole; oral, rectal
1.6
11.1
404
2973
EG1DG
NOMESCO Finland
Very extensive MRI examination of mandibular joint with high intensity magnet
43.8
10.9
13
*
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
10.7
10.8
20
19
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
21.7
10.7
15
7
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
13.1
10.7
18
14
EEC02
NOMESCO Finland
Rapid expansion of maxilla
60.6
10.6
12
*
XX1XW
NOMESCO Finland
Extensive written report from radiologist
3.9
10.4
30
78
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
111.1
10.4
11
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.7
10.4
56
215
L01BA01
ATC
methotrexate; systemic
3.2
10.3
41
133
EMAK, ,
NOMESCO Finland
2.7
10.1
53
201
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
7.7
9.9
22
29
SPC10
NOMESCO Finland
Standard dental crown
4.0
9.9
28
72
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
9.6
337
2443
EB1S1
NOMESCO Finland
Photography of teeth
9.2
9.5
19
21
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
5.1
9.1
19
38
EBA10
NOMESCO Finland
Operative extraction of tooth
1.7
9.1
169
1044
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.0
9.1
106
566
G47.3
ICD-10 Finland
Sleep apnoea
1.6
8.9
234
1581
P01BA02
ATC
hydroxychloroquine; oral
2.1
8.7
83
411
K07.61
ICD-10 Finland
Cracking jaw joint
3.1
8.7
35
114
EGC30
NOMESCO Finland
Prosthetic replacement of mandibular joint
50.4
8.7
10
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.2
8.6
69
319
ECA50
NOMESCO Finland
Periodontal flap surgery
4.8
8.6
19
40
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
10.1
8.5
16
16
K03.30
ICD-10 Finland
Internal granuloma of pulp
10.1
8.5
16
16
Z01.2
ICD-10 Finland
Dental examination
1.5
8.5
504
4044
K07.35
ICD-10 Finland
Impacted or embedded teeth with abnormal position of such teeth or adjacent teeth
6.5
8.5
21
33
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
3.7
8.5
26
71
R51.81
ICD-10 Finland
Facial pain NOS
3.2
8.4
33
106
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
8.4
755
6567
SCA01
NOMESCO Finland
Preventive oral health care, short
1.5
8.4
372
2817
L04AA13
ATC
[U] leflunomide
3.4
8.4
30
91
K07.02
ICD-10 Finland
Micrognatia (hypoplasia) of both jaws
+∞
8.3
8
*
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.6
8.2
46
181
A07EC01
ATC
sulfasalazine; oral, rectal
2.0
7.9
82
419
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
7.9
254
1794
Z47.0
ICD-10 Finland
Follow-up care involving removal of fracture plate and other internal fixation device
7.8
7.9
17
22
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
8.5
7.8
16
19
G44.2
ICD-10 Finland
Tension-type headache
1.7
7.8
150
934
R06.5
ICD-10 Finland
Mouth breathing
1.9
7.8
100
552
-, ,
ICD-10 Finland
3.6
7.7
25
71
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.9
7.7
107
606
K07.68
ICD-10 Finland
Other disorders of the jaw joint
6.8
7.6
18
27
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
7.6
322
2408
H02AB06
ATC
prednisolone; systemic
1.4
7.5
430
3403
J34.2
ICD-10 Finland
Deviated nasal septum
2.2
7.5
65
311
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.5
7.4
372
2872
SJE90
NOMESCO Finland
Orthodontic finishing
7.7
7.4
16
21
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
8.4
7.3
15
18
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
7.3
501
4092
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
7.3
132
808
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
15.9
7.2
11
7
R01AD09
ATC
mometasone; nasal
1.4
7.2
466
3764
M01CB01
ATC
sodium aurothiomalate; parenteral
6.6
7.1
17
26
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
8.0
7.1
15
19
EGA00
NOMESCO Finland
Arthroscopy of mandibular joint
12.1
7.1
12
10
EG1CG
NOMESCO Finland
Extensive MRI examination of mandibular joint with high intensity magnet
10.1
7.0
13
13
T84.62
ICD-10 Finland
Osteitis associated with dental implants
10.1
7.0
13
13
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
5.9
6.9
18
31
SPA02
NOMESCO Finland
Preparation for dental prosthetics
2.7
6.9
35
131
SPF20
NOMESCO Finland
Temporary relining of dentures
8.3
6.8
14
17
R19.5
ICD-10 Finland
Other faecal abnormalities
3.8
6.8
20
53
K00.09
ICD-10 Finland
Lack of teeth due to lack of dental development UNS
4.3
6.8
17
40
QA9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head or neck, unspecified
40.3
6.8
8
*
ZXX07
NOMESCO Finland
Extent of procedure, 7 units
40.3
6.8
8
*
EEC45
NOMESCO Finland
Reconstruction of maxilla using bone graft
40.3
6.8
8
*
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
40.3
6.8
8
*
ECB10
NOMESCO Finland
Reconstruction of gingiva
40.3
6.8
8
*
EDC45
NOMESCO Finland
Reconstruction of mandible using bone graft
40.3
6.8
8
*
OIKK, ,
NOMESCO Finland
2.3
6.7
51
231
WZA90
NOMESCO Finland
Other medical or dental certificate
1.5
6.7
255
1862
R01AD12
ATC
fluticasone furoate; nasal
1.4
6.6
339
2619
ZXA00
NOMESCO Finland
Right side
1.5
6.6
216
1528
7849C
ICD-9 Finland
Symptoms involving head and neck, Other symptoms involving head and neck[KUORSAUS]
14.4
6.4
10
7
L04AB04
ATC
adalimumab; parenteral
2.7
6.4
32
119
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
6.3
705
6199
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
3.0
6.3
26
87
4346
FHL
Jaw joint plastic (graft, ectomy)
+∞
6.3
6
*
4319
FHL
Other measure in this category
+∞
6.3
6
*
52499
ICD-8 Finland
Dento-facial anomalies including malocclusion, Other and unspecified
+∞
6.3
6
*
EEW99
NOMESCO Finland
Other operation on maxilla
+∞
6.3
6
*
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
3.2
6.2
24
77
SPB20
NOMESCO Finland
Temporary bridge
7.7
6.1
13
17
ECA00
NOMESCO Finland
Surgical exposure of tooth
7.7
6.1
13
17
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.2
6.1
47
215
ZXE00
NOMESCO Finland
One hour or less
1.4
6.1
359
2834

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
542
4125
1.64
13.83
3.9
3.1
0.00
0.00
estimate
0.50
126
801
457
3385
1.61
12.66
3.7
2.9
5.89
5.86
ph
0.06
40
325
536
4167
1.58
11.82
3.9
3.1
0.00
0.01
estimate
0.80
111
746
314
2163
1.64
11.44
4.0
3.4
0.01
0.01
estimate
0.01
112
762
530
4130
1.56
11.43
5.3
4.3
0.01
0.00
estimate
0.40
118
785
508
3924
1.56
11.37
10.3
8.9
0.01
0.00
e9/l
0.40
436
3212
784
6752
1.61
10.36
4.6
3.9
14.49
14.52
pmol/l
0.11
728
6220
683
5778
1.51
9.09
3.6
3.2
—
—
—
0
0
735
6379
1.49
8.10
8.1
7.3
74.35
79.65
u/l
3.90
696
6036
361
2758
1.47
7.65
3.8
3.6
28.82
83.10
e6/l
2.05
262
1893
286
2108
1.49
7.19
3.4
3.0
0.38
0.37
e6/l
0.01
228
1576
360
2779
1.45
7.12
3.0
3.0
72.52
38.77
ng/l
0.50
215
1667
721
6308
1.44
7.03
4.7
3.9
9.11
10.19
mm/h
1.97
675
5895
306
2302
1.46
6.90
3.4
3.1
18.04
80.04
e6/l
1.44
246
1754
620
5293
1.41
6.85
4.4
3.7
50.83
841.85
e6/l
0.90
12
71
659
5694
1.41
6.74
4.4
3.8
—
—
—
0
0
592
5031
1.40
6.61
9.8
9.3
3.89
3.94
e9/l
0.20
517
4406
220
1579
1.50
6.21
2.6
2.5
5.12
6.61
e6/l
0.90
195
1417
428
3470
1.39
6.21
2.4
2.4
75.25
74.35
nmol/l
0.29
399
3185
210
1494
1.51
6.19
3.4
2.7
581.47
559.65
mosm/kgh2o
0.57
173
1300
475
3920
1.38
6.18
3.3
2.8
107.70
105.24
ug/l
0.09
454
3663
457
3754
1.38
6.09
5.9
7.1
1.21
1.21
mmol/l
0.29
390
3226
52
248
2.15
6.08
1.3
1.2
—
—
—
0
0
400
3219
1.39
6.02
5.0
5.1
36.74
36.56
g/l
0.29
378
3026
536
4523
1.37
6.02
7.8
6.3
1.92
2.01
e9/l
0.61
475
4046
130
836
1.63
5.95
2.5
2.2
380.08
368.24
nmol/l
0.29
119
777
536
4533
1.37
5.89
8.0
6.7
0.20
0.19
e9/l
0.39
477
4021
136
895
1.60
5.67
1.4
1.4
—
—
—
0
0
494
4143
1.36
5.64
8.2
6.8
—
—
—
0
0
114
719
1.66
5.63
3.6
3.4
—
—
—
0
0
257
1936
1.43
5.60
2.0
2.0
1.05
1.07
mg/l
0.02
193
1445
274
2091
1.42
5.55
3.3
3.0
—
—
—
0
0
517
4377
1.35
5.50
7.8
6.3
0.54
0.56
e9/l
0.75
451
3826
947
8885
1.59
5.35
14.4
11.8
20.46
21.78
mg/l
0.58
742
6816
516
4382
1.34
5.32
7.8
6.3
0.04
0.04
e9/l
0.56
448
3825
873
8059
1.46
5.28
5.2
4.5
1.79
1.97
mu/l
0.65
816
7517
248
1876
1.42
5.25
3.8
3.1
—
—
—
0
0
300
2348
1.39
5.20
3.4
2.7
—
—
—
0
0
248
1889
1.41
5.02
2.4
2.1
2.74
2.89
mg/l
0.58
216
1628
110
711
1.61
4.94
2.6
2.9
9.85
10.31
g/l
0.85
99
659
81
489
1.71
4.74
1.3
1.3
—
—
—
0
0
489
4177
1.32
4.61
6.4
6.5
10.87
11.26
umol/l
0.48
469
3971
269
2104
1.37
4.61
4.4
4.1
92.53
93.79
%
0.39
260
2051
352
2870
1.34
4.60
1.9
1.8
99.37
96.71
pmol/l
0.44
192
1513
285
2252
1.36
4.58
2.0
2.1
199.43
218.01
u/l
0.18
270
2133
208
1565
1.41
4.48
1.3
1.3
20.18
29.31
iu/ml
1.44
74
507
142
1000
1.48
4.35
1.8
1.6
—
—
—
0
0
857
7964
1.39
4.30
16.6
14.2
13.98
14.38
%
1.90
849
7827
70
418
1.72
4.28
1.9
1.6
341.03
296.21
mu/l
0.39
63
377
239
1855
1.37
4.27
4.2
3.2
1.02
1.02
kg/l
0.04
31
231
171
1258
1.43
4.17
3.4
2.7
1.04
0.94
e6/l
0.15
105
698
537
4690
1.29
4.13
4.7
4.8
6.46
6.55
mmol/l
0.57
508
4358
463
3972
1.29
4.07
7.9
6.4
0.70
0.68
%
0.46
432
3731
89
574
1.60
4.06
2.8
3.6
1.23
1.23
mmol/l
0.10
78
499
92
600
1.58
4.01
3.9
3.1
—
—
—
0
0
150
1088
1.44
3.95
1.3
1.2
—
—
—
0
0
92
603
1.58
3.93
4.7
4.7
0.11
0.13
%
0.09
19
175
936
8867
1.45
3.90
14.5
12.8
139.73
139.70
mmol/l
0.19
923
8657
275
2208
1.33
3.90
3.6
3.9
7.39
7.40
ph
1.07
54
416
88
572
1.59
3.90
1.6
1.7
1.18
1.28
g/l
0.41
78
532
260
2073
1.34
3.86
1.8
1.9
—
—
—
0
0
476
4117
1.28
3.86
7.8
6.4
2.90
2.88
%
0.07
446
3878
478
4139
1.28
3.83
8.0
6.6
8.32
8.44
%
0.39
448
3904
938
8896
1.45
3.82
14.6
12.9
3.94
3.94
mmol/l
0.23
923
8663
253
2014
1.34
3.80
1.5
1.4
2.13
2.29
g/l
0.73
160
1261
37
189
1.99
3.71
4.5
4.2
54.62
55.43
%
0.16
37
189
484
4220
1.27
3.60
7.6
6.1
55.87
55.94
%
0.04
455
3991
168
1269
1.38
3.52
1.3
1.3
600.00
539.85
titre
0.10
22
264
311
2572
1.30
3.52
2.6
2.6
55.71
58.75
u/l
0.26
291
2410
981
9414
1.52
3.47
12.4
10.7
—
—
—
0
0
163
1230
1.38
3.43
1.5
1.6
—
—
—
0
0
40
217
1.88
3.40
4.3
4.2
1.46
1.38
mmol/l
0.20
40
211
488
4279
1.26
3.40
7.9
6.3
29.46
29.46
%
0.00
460
4051
394
3369
1.27
3.39
5.7
6.5
1.21
1.21
mmol/l
0.62
366
3111
71
461
1.58
3.20
2.7
2.3
3460.04
3605.49
u/l
0.02
28
188
856
8055
1.32
3.19
17.8
14.7
333.60
333.68
g/l
0.09
850
7996
92
634
1.49
3.17
4.7
4.6
0.05
0.15
%
0.89
19
208
16
61
2.65
3.14
1.3
1.2
1.05
1.05
ratio
—
6
27
150
1134
1.38
3.13
2.3
2.0
—
—
—
0
0
162
1240
1.36
3.12
3.1
2.7
2.43
2.43
mmol/l
0.20
146
1096
56
345
1.66
3.12
1.7
1.6
11.81
9.06
u/l
0.62
39
282
96
671
1.47
3.09
4.5
4.5
1.17
1.00
%
0.18
23
246
31
160
1.97
3.07
7.1
3.5
—
—
—
0
0
100
712
1.45
2.94
2.7
2.2
12.21
12.99
nmol/l
0.43
89
654
257
2118
1.28
2.93
3.2
2.4
—
—
—
0
0
25
122
2.07
2.88
1.6
1.8
—
—
—
0
0
6
9
6.70
2.87
3.3
2.7
174.67
114.00
ug/g
—
6
9
141
1073
1.36
2.83
2.1
2.5
2.44
2.41
g/l
0.31
130
996
186
1478
1.31
2.79
1.8
1.6
454.23
40613154.71
pmol/l
1.90
162
1273
21
97
2.19
2.78
1.3
1.3
—
—
—
0
0
41
240
1.74
2.77
1.2
1.1
2.81
2.59
u/ml
0.05
24
135
211
1708
1.29
2.76
3.0
3.0
531.43
781.25
ng/l
1.53
173
1410
305
2583
1.25
2.75
3.0
3.3
2.36
2.36
mmol/l
0.31
280
2344
198
1590
1.30
2.75
1.6
1.5
20.49
20.78
nmol/l
0.12
180
1392
39
226
1.75
2.73
1.4
1.5
295.02
301.91
ug/g
0.07
25
129
32
175
1.85
2.70
2.7
2.2
63.88
108.82
ug/min
0.41
17
109
871
8269
1.29
2.66
4.2
3.9
5.78
5.83
mmol/l
0.47
821
7690
40
236
1.72
2.64
1.1
1.1
—
—
—
0
0
87
617
1.45
2.63
4.7
4.2
0.94
0.64
%
0.32
18
211
346
2986
1.23
2.62
3.4
3.4
31.95
31.81
u/l
0.03
332
2849
375
3265
1.23
2.61
11.7
9.7
1.17
1.15
inr
0.31
132
989
263
2205
1.26
2.58
7.4
7.0
—
—
—
0
0
56
364
1.57
2.56
3.0
3.0
22.48
21.46
s
0.56
44
326
12
44
2.75
2.55
1.0
1.1
—
—
—
0
0
144
1118
1.33
2.54
1.7
1.6
1271.83
1186.78
nmol/l
0.51
114
856
38
224
1.72
2.53
1.0
1.1
8.65
8.01
u/ml
0.05
23
128
157
1237
1.32
2.50
2.6
2.5
103.61
108.09
ug/g
0.09
129
987
20
95
2.13
2.50
1.4
1.3
7.38
6.59
g/l
0.44
15
67
20
95
2.13
2.50
1.4
1.3
0.37
0.35
g/l
0.09
15
65
20
95
2.13
2.50
1.4
1.3
3.09
2.65
g/l
0.61
15
65
102
756
1.39
2.43
3.5
3.7
1.84
1.74
%
0.45
89
689
148
1164
1.32
2.40
2.3
2.5
16.03
14.15
umol/l
2.03
141
1094
65
444
1.49
2.39
1.0
1.1
—
—
—
0
0
976
9444
1.39
2.39
11.4
9.5
28.12
27.90
u/l
0.13
945
9178
36
213
1.71
2.38
1.0
1.1
0.65
1.23
u/ml
0.36
21
102
81
579
1.43
2.37
3.1
3.3
4.40
4.64
pmol/l
1.51
73
511
185
1504
1.28
2.33
1.3
1.2
7.21
10.43
u/ml
0.38
90
609
41
253
1.65
2.33
1.5
2.2
1.25
1.42
g/l
0.45
35
219
127
987
1.33
2.24
1.4
1.4
—
—
—
0
0
203
1685
1.25
2.16
1.5
1.7
—
—
—
0
0
51
339
1.53
2.15
5.3
2.7
—
—
—
0
0
99
749
1.35
2.10
7.9
9.0
1.87
0.96
mmol/l
1.20
75
610
127
998
1.31
2.08
1.7
1.5
—
—
—
0
0
264
2266
1.22
2.05
1.4
1.3
1.00
1.57
u/ml
0.95
72
592
126
993
1.30
2.03
2.3
2.6
26.71
24.26
%
1.05
112
864
58
403
1.46
2.00
4.0
5.5
—
—
—
0
0
67
480
1.42
1.97
2.7
2.9
109.09
129.87
ng/l
0.39
59
438
33
205
1.63
1.88
1.3
1.2
57.36
53.24
u/ml
—
5
19
11
46
2.41
1.85
1.2
1.1
204.36
540.18
u/l
0.74
11
40
40
264
1.54
1.78
1.2
1.3
—
1515.00
—
0
8
28
169
1.67
1.78
1.2
1.0
3.89
4.62
u/ml
0.11
19
81
154
1271
1.25
1.73
4.4
4.4
0.85
0.81
mmol/l
2.50
141
1214
25
148
1.71
1.71
1.5
1.8
0.71
0.80
g/l
0.16
19
113
1029
10109
1.50
1.70
20.8
17.2
256.05
256.26
e9/l
0.03
1021
9871
86
662
1.33
1.67
8.9
10.4
—
—
—
0
0
13
62
2.11
1.66
1.0
1.1
—
—
—
0
0
15
76
1.99
1.65
1.0
1.1
0.80
1.07
u/ml
—
5
30
39
262
1.51
1.63
1.2
1.3
66.25
85.77
titre
—
8
26
21
121
1.75
1.59
3.7
2.8
20.33
23.34
nmol/l
0.74
21
115
7
26
2.70
1.58
1.6
1.0
—
—
—
0
0
1029
10119
1.47
1.57
20.8
17.2
4.58
4.58
e12/l
0.03
1019
9860
1029
10120
1.47
1.56
20.8
17.2
6.51
6.63
e9/l
1.06
1020
9858
13
64
2.04
1.54
1.0
1.1
—
—
—
0
0
238
2078
1.19
1.53
2.4
2.6
5500.27
3742.25
umol/l
0.24
225
1873
95
1187
0.78
1.52
1.3
1.4
—
—
—
0
0
20
117
1.72
1.45
1.8
1.6
—
—
—
0
0
394
3593
1.15
1.45
3.0
2.5
—
—
—
0
0
48
345
1.41
1.45
1.1
1.4
—
8.82
—
0
12
26
164
1.60
1.44
1.1
1.2
7.80
5.42
u/ml
—
10
66
1027
10107
1.43
1.43
21.1
17.3
40.36
41.28
%
1.12
977
9574
121
997
1.24
1.41
2.4
3.3
8.46
7.59
umol/l
0.14
103
863
361
3278
1.15
1.41
1.9
2.0
—
—
—
0
0
896
8688
1.20
1.35
4.7
4.4
2.88
2.87
mmol/l
0.15
850
8182
14
75
1.88
1.34
2.5
4.4
—
—
—
0
0
45
325
1.40
1.34
3.9
3.3
0.63
0.66
%
0.37
45
325
801
7700
1.16
1.33
5.4
4.9
38.95
38.94
mmol/mol
0.01
758
7262
95
767
1.26
1.33
2.5
2.5
36.80
102.29
u/l
0.53
85
658
141
1189
1.21
1.33
3.6
2.9
4.55
2.49
e6/l
0.70
79
632
24
152
1.59
1.32
1.1
1.1
5.55
8.41
u/ml
0.30
13
59
855
8263
1.17
1.31
4.1
3.6
1.31
1.31
mmol/l
0.07
805
7767
657
6235
1.14
1.29
3.3
3.2
49.20
47.40
u/l
0.21
623
5942
886
8591
1.18
1.29
4.4
4.0
4.78
4.77
mmol/l
0.21
843
8132
68
529
1.30
1.27
1.5
1.5
19.68
26.69
iu/l
1.03
53
439
56
424
1.34
1.26
1.0
1.1
—
—
—
0
0
18
107
1.69
1.26
1.5
1.8
—
—
—
0
0
89
720
1.26
1.24
1.3
1.2
121.93
144.37
iu/ml
0.22
38
288
75
594
1.28
1.24
1.4
1.7
—
—
—
0
0
22
139
1.60
1.24
1.0
1.0
1.08
0.45
u/ml
—
7
44
285
2567
1.15
1.23
2.3
2.3
—
—
—
0
0
422
3909
1.13
1.19
2.5
2.5
—
—
—
0
0
36
256
1.42
1.19
5.9
4.6
—
—
—
0
0
14
79
1.78
1.17
2.1
1.5
—
—
—
0
0
11
57
1.94
1.17
1.2
1.9
—
—
—
0
0
11
198
0.55
1.16
1.2
1.2
—
—
—
0
0
24
158
1.53
1.15
1.2
1.1
—
—
—
0
0
14
80
1.76
1.13
4.4
2.4
—
—
—
0
0
10
51
1.97
1.11
2.2
2.3
868.80
577.47
ml
—
5
30
52
670
0.76
1.10
1.7
1.4
—
—
—
0
0
14
81
1.74
1.09
4.4
2.5
3.97
3.99
mmol/l
0.06
14
81
14
81
1.74
1.09
4.4
2.5
106.64
105.68
mmol/l
0.37
14
81
67
536
1.27
1.05
2.7
3.3
72.71
72.14
e9/l
0.04
39
401
13
75
1.74
1.03
1.0
1.1
—
—
—
0
0
30
213
1.42
1.02
1.2
1.1
0.48
2.27
u/ml
2.58
15
118
879
8563
1.15
0.99
4.4
4.0
1.47
1.46
mmol/l
0.36
834
8072
69
559
1.25
0.98
1.2
1.2
—
—
—
0
0
25
174
1.45
0.95
1.5
1.4
31.19
23.77
u/l
0.44
19
146
7
37
1.90
0.94
1.7
1.3
—
—
—
0
0
52
412
1.28
0.90
1.8
2.3
—
—
—
0
0
53
421
1.27
0.90
4.2
3.8
132.08
130.02
g/l
0.29
53
413
6
29
2.07
0.89
2.2
2.3
—
—
—
0
0
16
241
0.66
0.88
1.3
1.4
—
—
—
0
0
207
1868
1.13
0.88
5.5
4.1
—
—
—
0
0
21
144
1.47
0.87
3.0
3.2
—
—
—
0
0
10
57
1.76
0.83
1.3
1.1
—
—
—
0
0
8
46
1.74
0.82
10.1
3.0
547.75
654.13
u/ml
—
8
46
14
89
1.58
0.81
2.4
2.6
42.09
37.64
%
0.58
14
89
6
33
1.82
0.79
1.0
1.3
—
—
—
0
0
16
234
0.68
0.78
1.2
1.4
—
—
—
0
0
16
233
0.68
0.77
1.2
1.4
—
—
—
0
0
6
34
1.77
0.76
2.2
1.7
—
—
—
0
0
10
59
1.70
0.76
2.7
5.0
—
—
—
0
0
10
59
1.70
0.76
1.0
1.0
—
—
—
0
0
84
718
1.18
0.75
4.9
5.4
2.43
1.88
mmol/l
0.81
76
590
57
469
1.23
0.75
2.1
2.1
—
—
—
0
0
30
227
1.33
0.75
2.7
3.5
—
—
—
0
0
22
159
1.39
0.72
3.0
4.0
2.68
2.58
mmol/l
0.05
13
104
11
68
1.62
0.72
1.0
1.0
0.13
5.16
u/ml
—
6
19
12
76
1.59
0.72
1.2
1.5
158.08
179.23
pmol/l
0.34
12
76
158
1423
1.13
0.71
3.6
3.4
463.63
474.28
ng/l
0.01
120
978
15
101
1.49
0.70
2.2
4.2
—
—
—
0
0
15
101
1.49
0.70
1.5
2.6
—
—
—
0
0
7
41
1.71
0.70
1.1
1.4
127.86
151.07
nmol/l
—
7
41
7
41
1.71
0.70
2.4
1.5
—
—
—
0
0
62
520
1.20
0.69
1.9
2.8
66.29
67.35
g/l
0.55
55
484
28
214
1.32
0.67
1.1
1.3
—
—
—
0
0
129
1152
1.14
0.67
1.8
1.7
—
—
—
0
0
32
250
1.29
0.66
1.6
1.2
—
—
—
0
0
27
206
1.32
0.66
1.3
1.9
4.00
6.51
e6/l
0.43
22
161
27
206
1.32
0.66
1.3
1.9
149.91
1020.76
e6/l
0.76
22
166
57
676
0.83
0.65
3.1
4.1
—
—
—
0
0
5
29
1.73
0.64
1.0
1.1
0.32
11.77
u/ml
—
5
24
67
572
1.18
0.63
1.6
1.4
—
—
—
0
0
21
155
1.36
0.63
2.4
3.3
18.51
25.78
mg/l
0.48
13
95
222
2056
1.10
0.62
3.6
3.3
—
—
—
0
0
14
96
1.46
0.61
1.1
1.1
—
—
—
0
0
21
156
1.35
0.61
1.2
1.1
—
—
—
0
0
35
431
0.81
0.59
2.8
4.8
—
—
—
0
0
10
64
1.57
0.58
1.0
1.0
—
—
—
0
0
87
765
1.15
0.58
2.3
2.8
0.22
0.23
g/l
0.09
82
724
91
803
1.15
0.58
1.5
1.5
—
—
—
0
0
137
1243
1.12
0.57
1.4
1.5
—
—
—
0
0
235
2192
1.09
0.57
4.1
3.7
1.84
1.85
ug/l
0.01
214
2002
11
73
1.51
0.56
1.4
1.5
1.78
1.50
nmol/l
0.38
11
67
20
150
1.34
0.56
1.3
1.2
—
—
—
0
0
38
312
1.23
0.55
1.1
1.2
—
—
—
0
0
43
358
1.21
0.54
1.7
1.6
—
—
—
0
0
90
799
1.14
0.53
1.2
1.2
—
—
—
0
0
9
63
1.43
0.52
1.2
1.3
—
—
—
0
0
6
40
1.50
0.51
1.2
1.3
—
—
—
0
0
6
40
1.50
0.51
1.0
1.1
2154.83
1712.60
miu/ml
—
6
40
16
118
1.36
0.50
1.1
1.7
—
—
—
0
0
17
127
1.34
0.49
2.6
1.7
—
—
—
0
0
7
49
1.43
0.46
1.0
1.0
—
—
—
0
0
21
165
1.28
0.45
1.8
3.1
3.24
8.52
umol/l
1.98
14
120
13
95
1.37
0.44
9.9
6.0
11.36
10.75
mg/l
0.28
13
86
21
166
1.27
0.43
2.5
2.0
142.13
133.69
g/l
0.55
15
131
5
31
1.62
0.43
1.2
2.1
—
—
—
0
0
28
230
1.22
0.43
1.3
1.8
376.04
451.00
mg/l
1.50
28
214
8
56
1.43
0.42
1.0
1.2
5.64
6.64
mmol/l
—
8
51
17
131
1.30
0.42
5.2
4.2
157.32
263.99
u/ml
0.20
17
123
8
58
1.38
0.41
2.4
2.1
—
—
—
0
0
5
33
1.52
0.41
1.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
0.54
—
0
7
0
15
0.00
0.41
0.0
1.3
—
1.90
—
0
15
8
59
1.36
0.41
1.0
1.1
—
—
—
0
0
17
132
1.29
0.40
2.8
2.7
—
—
—
0
0
29
241
1.21
0.40
1.3
1.2
5.48
13.16
u/ml
—
5
35
5
34
1.47
0.40
2.4
4.0
—
—
—
0
0
12
88
1.37
0.40
1.3
2.0
—
—
—
0
0
0
18
0.00
0.40
0.0
6.6
—
—
—
0
0
8
61
1.31
0.39
1.0
1.1
479.63
398.36
nmol/l
—
8
53
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
32
270
1.19
0.39
1.1
1.1
—
—
—
0
0
23
188
1.23
0.37
2.9
3.8
7.42
7.42
ph
0.10
23
166
9
70
1.29
0.36
1.1
1.1
—
—
—
0
0
9
71
1.27
0.36
1.2
1.7
—
—
—
0
0
34
291
1.17
0.36
5.6
4.9
0.27
0.29
g/l
0.04
19
156
6
42
1.43
0.35
1.2
1.1
137.00
249.31
iu/ml
—
6
42
6
44
1.37
0.34
1.8
1.4
—
—
—
0
0
20
163
1.23
0.34
3.9
3.4
—
—
—
0
0
29
247
1.18
0.33
2.0
1.9
2.50
4.65
iu/l
2.41
16
92
16
198
0.81
0.32
2.9
2.1
—
—
—
0
0
6
47
1.28
0.32
1.5
1.5
4.82
6.18
mmol/l
—
6
47
31
267
1.17
0.31
2.5
3.3
2820.66
968.38
u/ml
0.32
25
228
7
96
0.73
0.31
1.0
1.2
—
—
—
0
0
112
1046
1.08
0.30
5.9
7.0
1.05
1.07
mmol/l
0.37
105
987
11
84
1.31
0.30
1.2
1.1
173.27
245.59
mg/l
2.59
11
70
47
420
1.12
0.30
1.1
1.1
—
0.90
—
0
5
67
730
0.91
0.28
1.4
1.4
—
—
—
0
0
16
131
1.22
0.27
1.1
4.1
—
—
—
0
0
26
224
1.16
0.27
1.9
1.3
—
—
—
0
0
13
161
0.81
0.27
1.2
1.2
—
—
—
0
0
19
159
1.20
0.27
3.4
4.3
—
—
—
0
0
8
66
1.21
0.26
1.0
1.4
62.75
75.53
umol/l
—
8
66
42
376
1.12
0.26
12.1
11.7
—
—
—
0
0
5
72
0.69
0.26
5.0
3.0
63.80
53.06
%
—
5
66
22
188
1.17
0.25
1.6
1.5
0.61
0.30
nmol/l
0.69
15
150
9
74
1.22
0.25
1.4
1.6
—
—
—
0
0
14
114
1.23
0.25
1.4
1.2
—
—
—
0
0
16
191
0.84
0.24
1.1
1.1
—
8.94
—
0
12
25
217
1.16
0.24
1.8
2.4
—
—
—
0
0
11
87
1.27
0.24
1.3
1.2
36.00
34.72
mg/l
0.05
11
68
10
78
1.28
0.24
1.0
1.4
8.11
0.62
u/ml
—
5
40
10
78
1.28
0.24
1.3
1.2
—
—
—
0
0
35
391
0.89
0.24
1.3
1.3
143.28
245.00
miu/ml
1.77
18
189
17
143
1.19
0.23
3.4
2.3
17.08
16.97
%
—
9
81
16
134
1.20
0.23
2.3
1.5
—
—
—
0
0
5
39
1.28
0.23
1.0
1.0
—
—
—
0
0
203
1957
1.05
0.21
2.1
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
9.8
—
—
—
0
0
255
2628
0.96
0.21
1.6
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
4.60
—
0
7
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
6
48
1.25
0.20
1.5
1.6
—
—
—
0
0
16
136
1.18
0.20
1.3
1.4
—
—
—
0
0
198
2048
0.96
0.19
3.2
3.2
65.91
345.59
mg/l
2.29
120
1337
6
51
1.18
0.19
1.3
1.2
—
—
—
0
0
11
132
0.83
0.18
2.9
2.5
—
—
—
0
0
7
60
1.17
0.18
1.1
1.4
1.34
1.54
g/l
—
7
60
37
339
1.09
0.17
3.2
2.2
—
—
—
0
0
60
563
1.07
0.17
2.6
4.5
7.43
7.41
ph
—
9
66
5
69
0.72
0.17
1.0
1.2
—
—
—
0
0
5
70
0.71
0.16
2.2
5.3
14.50
11.40
%
—
5
70
8
70
1.14
0.16
1.3
1.2
—
—
—
0
0
8
71
1.13
0.16
1.1
1.6
0.83
1.00
g/l
—
8
71
9
79
1.14
0.15
1.9
2.8
34.33
32.84
pg
—
9
79
23
207
1.11
0.15
1.3
1.1
—
—
—
0
0
19
169
1.13
0.14
1.2
1.1
—
—
—
0
0
23
208
1.11
0.14
1.3
1.1
—
—
—
0
0
53
561
0.94
0.13
2.9
4.6
73.99
76.08
ng/l
0.07
48
512
35
325
1.08
0.13
1.8
1.7
—
—
—
0
0
15
169
0.89
0.12
1.1
1.1
0.77
1.79
u/ml
—
8
78
56
588
0.95
0.11
1.6
2.5
3.77
6.70
e9/l
1.76
48
508
22
240
0.91
0.11
1.3
1.6
—
—
—
0
0
13
115
1.13
0.10
4.8
3.7
1.00
1.19
%
0.15
13
107
10
87
1.15
0.09
3.2
3.5
—
—
—
0
0
11
124
0.89
0.09
1.5
1.2
—
—
—
0
0
29
272
1.07
0.09
6.5
8.9
—
—
—
0
0
21
194
1.08
0.09
1.4
2.0
—
—
—
0
0
6
55
1.09
0.09
1.2
1.4
33.57
34.09
g/l
—
6
50
51
532
0.96
0.08
1.9
1.9
—
—
—
0
0
15
136
1.10
0.08
1.0
1.1
1.50
1.45
g/l
0.20
15
124
109
1062
1.03
0.08
1.6
1.7
—
—
—
0
0
55
571
0.96
0.08
2.0
1.8
—
—
—
0
0
65
672
0.97
0.07
4.2
4.4
3.66
17.81
ug/l
1.16
50
534
6
73
0.82
0.07
1.8
3.0
—
—
—
0
0
48
461
1.04
0.07
1.1
1.4
—
—
—
0
0
222
2250
0.98
0.07
1.6
1.7
1.41
1.43
mmol/l
0.10
184
1945
8
91
0.88
0.06
1.3
1.3
—
—
nmol/l
—
0
0
22
207
1.06
0.06
1.9
1.6
—
—
—
0
0
242
2448
0.99
0.06
3.3
3.2
8.35
8.25
mmol/l
0.12
213
2133
104
1019
1.02
0.06
1.2
1.2
—
—
—
0
0
59
577
1.02
0.03
1.9
1.8
—
—
—
0
0
11
102
1.08
0.03
1.2
1.3
—
0.55
—
0
6
59
579
1.02
0.03
1.9
1.8
—
—
—
0
0
58
572
1.01
0.01
1.9
1.8
—
—
—
0
0
216
2154
1.00
0.00
3.6
3.8
7.13
8.76
mg/mmol
0.29
131
1380
10
96
1.04
0.00
1.2
1.3
—
—
—
0
0
11
106
1.04
0.00
1.0
1.1
—
—
—
0
0
12
122
0.98
0.00
2.3
1.4
—
—
—
0
0
130
1301
1.00
0.00
2.6
2.5
0.71
0.68
ug/l
0.15
82
749
14
143
0.98
0.00
1.3
1.3
—
—
—
0
0
44
443
0.99
0.00
2.0
1.9
—
—
—
0
0
25
255
0.98
0.00
2.6
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
-0.00
3.2
2.9
37780.00
39612.82
ug/l
—
5
55
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
14.52
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
56
0.89
-0.00
3.4
2.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
297.00
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
17.17
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
-0.00
1.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
322.14
—
0
7
0
5
0.00
-0.00
0.0
2.4
—
190.40
—
0
5
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
8
82
0.98
-0.00
1.1
1.0
286.63
284.68
mg/l
—
8
72
9
89
1.01
-0.00
3.3
4.6
—
—
—
0
0
39
390
1.00
-0.00
2.3
2.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
50
1.00
-0.00
1.6
1.6
—
—
—
0
0
6
62
0.97
-0.00
46.8
34.8
8.07
7.24
ug/l
—
6
55
0
8
0.00
-0.00
0.0
4.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_MAJOR_ANOMALI_JAW_SIZE and mortality.

Females

Parameter HR [95% CI] p-value
K11_MAJOR_ANOMALI_JAW_SIZE 1.127 [0.86, 1.48] 0.383
Birth year 0.992 [0.98, 1.0] 0.089

During the follow-up period (1.1.1998 — 31.12.2019), 63 out of 4789 females with K11_MAJOR_ANOMALI_JAW_SIZE died.

Males

Parameter HR [95% CI] p-value
K11_MAJOR_ANOMALI_JAW_SIZE 0.887 [0.69, 1.14] 0.353
Birth year 0.987 [0.98, 1.0] 0.008

During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 4404 males with K11_MAJOR_ANOMALI_JAW_SIZE died.

Mortality risk

Mortality risk for people of age

years, who have K11_MAJOR_ANOMALI_JAW_SIZE.

N-year risk Females Males
1 0.115% 0.146%
5 0.521% 1.032%
10 1.407% 2.595%
15 2.921% 4.935%
20 5.07% 8.565%

Relationships between endpoints

Index endpoint: K11_MAJOR_ANOMALI_JAW_SIZE – Major anomalies of jaw size

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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