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Mandibular hypoplasia

EFO Endpoint Browser PheWeb

K11_MANDIBULAR_HYPOPL

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 — K07.04
  • Hospital discharge: ICD-10 — K07.04
  • Cause of death: ICD-10 — K07.04

3 out of 7 registries used, show all original rules.

237

4. Check minimum number of events

None

237

5. Include endpoints

None

237

6. Filter based on genotype QC (FinnGen only)

237

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3002 1649 1349
Only index persons 2772 1531 1241
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.04
Only index persons 0.05 0.06 0.05
Median age at first event (years)
Whole population 16.04 18.26 13.29
Only index persons 17.29 20.04 13.90

-FinnGen-

Key figures

All Female Male
Number of individuals 237 168 69
Unadjusted period prevalence (%) 0.05 0.06 0.03
Median age at first event (years) 37.03 35.89 39.81

-FinRegistry-

Age distribution of first events

010203040506070800.0k0.1k0.2k0.3k0.4k0.5k0.6k0.7k0.8k0.9k1.0k1.1kAgeIndividuals

-FinnGen-

Age distribution of first events

010203040506005101520253035404550AgeIndividuals

-FinRegistry-

Year distribution of first events

1970197519801985199019952000200520102015202020220.0k0.1k0.2k0.3k0.4k0.5k0.6k0.7k0.8k0.9k1.0kYearIndividuals

-FinnGen-

Year distribution of first events

1970197519801985199019952000200520102015202020230510152025303540455055YearIndividuals

-FinRegistry-

Cumulative Incidence Function

01020304050607080901000.00.10.20.30.40.50.60.70.80.91.0AgeProbability of first incidence (%)

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
211
Matched controls
2111
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
+∞
305.5
211
*
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
175.7
91.9
91
9
K07.13
ICD-10 Finland
Retrognaty, mandibular
80.2
83.9
92
20
SBB10
NOMESCO Finland
Teeth copy
19.0
65.4
111
116
SJX10
NOMESCO Finland
Short check-up visit for orthodontisk therapy
22.2
49.1
74
50
SJD00
NOMESCO Finland
Removal or reattacment of arrow in fixed orthodontisk device
22.7
47.6
71
46
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
19.4
46.6
74
57
K07.23
ICD-10 Finland
Deep bite
19.6
45.1
71
53
SJD20
NOMESCO Finland
Attachment of modifiable arrow of fixed orthodontisk device
26.1
43.9
62
33
EB1MA
NOMESCO Finland
Cephalometry with X-ray
19.5
40.9
64
46
SJD10
NOMESCO Finland
Attachment of arrow to fixed orthodontisk device
18.6
39.6
63
47
SJC50
NOMESCO Finland
Removal of orthodontisk device with at least 7 brackets
19.6
36.8
57
39
SAA04
NOMESCO Finland
Special inverstigation of mouth
12.5
35.5
68
77
SJC10
NOMESCO Finland
Orthodontic bandage in one tooth
21.3
34.1
51
31
SJB60
NOMESCO Finland
External device grinding and adaptation
19.9
27.7
42
26
SJD30
NOMESCO Finland
Demanding attachment of arrow to fixed orthodontisk device
18.3
27.5
43
29
K07.24
ICD-10 Finland
Open bite
30.7
27.2
36
14
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
10.6
25.6
52
63
K07.60
ICD-10 Finland
Snapping jaw
9.6
24.3
52
69
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
134.6
23.1
24
*
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
13.8
22.9
40
35
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
21.5
22.6
33
18
SJB00
NOMESCO Finland
Fitting of loose orthodontic device with user information
10.2
22.4
46
56
SJX20
NOMESCO Finland
Check-up visit for orthodontisk therapy
13.8
21.8
38
33
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
10.1
20.1
41
49
EEC05
NOMESCO Finland
Le Fort I osteotomy
116.0
19.9
21
*
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
116.0
19.9
21
*
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
5.4
19.3
65
160
SJD40
NOMESCO Finland
Fixation of ready made palatinal or lingual arrow
9.9
19.0
39
47
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
13.3
18.2
32
28
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
12.0
17.4
32
31
SJA01
NOMESCO Finland
Estimation of need for orthodontic care
+∞
16.9
16
*
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
16.1
16.8
27
19
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
9.9
16.7
34
40
K07.4
ICD-10 Finland
Malocclusion, unspecified
13.8
16.4
28
23
K07.10
ICD-10 Finland
Asymmetry of jaw
36.6
16.0
20
6
K07.0
ICD-10 Finland
Major anomalies of jaw size
+∞
15.8
15
*
SJC00
NOMESCO Finland
Bracket with fixed attachment
+∞
15.8
15
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.4
15.6
105
471
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
6.1
15.6
45
90
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
7.9
15.0
35
52
SJD50
NOMESCO Finland
Production and attachment of palatinal or lingual arrow
24.4
14.5
20
9
SXC05
NOMESCO Finland
Other oral or dental procedure
5.3
13.7
44
100
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
149.1
13.6
14
*
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
6.7
13.4
35
61
EBB10
NOMESCO Finland
Insertion of dental implant
20.7
13.2
19
10
SAA03
NOMESCO Finland
Extended examination of mouth
3.0
13.0
123
676
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
18.8
12.8
19
11
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.9
12.3
118
644
SJC40
NOMESCO Finland
Removal of orthodontisk device with at most 6 brackets
8.6
12.1
26
34
EDC30
NOMESCO Finland
Genioplasty
+∞
11.6
11
*
Z47.0
ICD-10 Finland
Follow-up care involving removal of fracture plate and other internal fixation device
126.6
11.5
12
*
SJX00
NOMESCO Finland
Reparation of orthodontiskt device by dentist
22.9
10.8
15
7
SJA04
NOMESCO Finland
Very demanding plan for orthodontic care
+∞
10.5
10
*
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
5.8
10.0
28
54
K07.14
ICD-10 Finland
Retrognaty, maxillary
57.7
9.7
11
*
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
104.5
9.5
10
*
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
22.9
9.5
13
6
EBB15
NOMESCO Finland
Insertion of dental implant abutment
38.5
9.1
11
*
SJB10
NOMESCO Finland
Fitting of loose orthodontic device with user information, demanding
11.4
9.0
16
15
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
7.2
8.9
21
32
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
5.4
8.9
26
53
SJA02
NOMESCO Finland
Plan for orthodontic care
52.2
8.7
10
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
4.3
8.6
32
84
SPC20
NOMESCO Finland
Attachment of crone of tooth to implant
28.8
8.6
11
*
SJA03
NOMESCO Finland
Demanding plan for orthodontic care
93.6
8.5
9
*
5240A
ICD-9 Finland
Dentofacial anomalies, including malocclusion, Major anomalies of jaw size
+∞
8.4
8
*
4343
FHL
Lower jaw open osteotomy
+∞
8.4
8
*
SPA20
NOMESCO Finland
Selection and insertion of implantdistans
46.7
7.8
9
*
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
46.7
7.8
9
*
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
19.2
7.7
11
6
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
26.1
7.6
10
*
ZXA10
NOMESCO Finland
Bilateral
2.9
7.6
49
197
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
5.4
7.3
21
42
EDC45
NOMESCO Finland
Reconstruction of mandible using bone graft
+∞
7.3
7
*
K07.9
ICD-10 Finland
Dentofacial anomaly, unspecified
+∞
7.3
7
*
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
14.4
7.0
11
8
SJE90
NOMESCO Finland
Finishing face of orthodontick therapy
41.4
6.8
8
*
G47.3
ICD-10 Finland
Sleep apnoea
2.6
6.6
50
223
P01BA02
ATC
hydroxychloroquine; oral
3.8
6.4
26
75
SHA04
NOMESCO Finland
Correction of physiology of bite - very demanding therapy visit
9.7
6.4
12
13
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
13.0
6.1
10
8
L04AA13
ATC
leflunomide; oral
9.0
6.1
12
14
K01.0
ICD-10 Finland
Embedded teeth
6.4
6.1
15
25
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
10.5
6.1
11
11
K07.61
ICD-10 Finland
Cracking jaw joint
10.5
6.1
11
11

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
37
113
3.70
10.65
3.8
3.6
—
—
—
0
0
85
472
2.25
7.74
4.0
3.2
0.00
0.01
estimate
0.50
24
185
195
1549
2.46
6.71
4.9
4.0
14.54
14.50
pmol/l
0.08
178
1432
73
403
2.17
6.59
4.2
3.2
—
—
—
0
0
135
936
2.03
6.57
3.5
3.0
0.00
0.00
estimate
0.00
24
183
109
737
1.89
5.37
3.5
2.8
—
—
—
0
0
131
943
1.87
5.27
4.5
4.2
0.00
0.01
estimate
0.50
26
187
131
954
1.83
4.97
3.5
3.0
0.00
0.00
estimate
0.00
24
178
67
412
1.87
4.27
4.4
3.0
1.02
1.02
kg/l
—
8
55
208
1834
2.10
3.52
5.5
4.6
1.74
1.79
mu/l
0.27
194
1723
7
11
6.52
3.21
2.0
1.5
—
—
—
0
0
73
499
1.67
3.13
4.3
5.0
—
—
—
0
0
33
180
1.97
2.96
1.2
1.4
—
—
—
0
0
141
1153
1.55
2.74
7.6
9.5
3.72
3.91
e9/l
0.51
125
1012
124
991
1.53
2.64
7.0
6.1
0.51
0.54
e9/l
0.61
114
877
29
158
1.95
2.62
1.4
1.7
—
—
—
0
0
5
7
7.27
2.56
2.2
1.6
60.40
36.00
%
—
5
7
33
190
1.86
2.54
1.5
1.3
—
—
—
0
0
127
1028
1.51
2.50
6.9
6.1
1.93
2.06
e9/l
0.46
116
924
148
1237
1.52
2.49
3.4
3.0
—
—
—
0
0
126
1019
1.50
2.48
6.9
6.7
0.20
0.18
e9/l
0.35
114
922
123
990
1.50
2.48
7.0
6.1
0.04
0.04
e9/l
0.72
112
876
74
544
1.52
2.26
2.2
3.2
2.36
2.35
mmol/l
0.33
68
493
223
2082
2.20
2.24
11.3
11.4
69.18
70.45
umol/l
0.60
223
2082
7
19
3.76
2.16
1.0
1.5
—
—
—
0
0
34
208
1.74
2.16
1.6
1.5
—
—
—
0
0
198
1789
1.65
2.16
3.9
3.4
1.23
1.27
mmol/l
0.33
191
1696
24
133
1.90
2.08
2.1
2.3
7144.19
2547.97
u/l
—
10
51
5
10
5.08
2.08
1.0
1.5
—
—
—
0
0
5
11
4.62
1.95
1.0
1.4
—
—
—
0
0
10
39
2.63
1.94
1.2
1.3
3.40
6.28
u/ml
—
5
18
47
323
1.57
1.92
1.5
1.5
20.81
21.83
nmol/l
0.25
42
278
78
600
1.45
1.86
1.8
1.8
100.14
95.40
pmol/l
0.43
46
322
83
646
1.44
1.86
2.9
3.2
13.21
63.30
e6/l
1.06
57
444
35
226
1.64
1.84
2.3
1.9
—
—
—
0
0
66
496
1.46
1.77
5.1
7.2
—
—
—
0
0
116
965
1.40
1.76
2.9
2.8
61.17
86.51
ug/l
3.84
111
908
12
55
2.24
1.70
1.9
2.5
2.51
8.48
umol/l
—
7
41
10
42
2.44
1.70
1.0
1.1
—
—
—
0
0
15
76
2.04
1.68
1.2
1.4
—
—
—
0
0
8
31
2.63
1.67
1.3
1.1
—
—
—
0
0
50
360
1.49
1.66
2.0
2.2
5.46
8.60
e6/l
0.53
42
323
87
698
1.39
1.61
5.9
5.9
1.21
1.22
mmol/l
0.45
79
648
161
1428
1.40
1.60
4.7
3.8
7.10
9.20
mm/h
2.76
148
1341
15
78
1.99
1.58
6.4
5.3
—
—
—
0
0
44
312
1.50
1.57
2.6
2.3
114.21
89.57
ug/g
0.32
34
250
8
33
2.47
1.55
2.4
1.2
—
—
—
0
0
40
279
1.52
1.54
1.6
1.6
—
—
—
0
0
64
492
1.41
1.51
2.5
2.8
0.24
0.35
e6/l
0.32
49
366
148
1302
1.36
1.50
3.9
3.7
—
—
—
0
0
107
897
1.35
1.48
7.8
8.1
0.00
0.00
e9/l
0.74
96
735
200
1856
1.50
1.45
4.2
3.8
1.50
1.49
mmol/l
0.16
193
1762
25
158
1.65
1.44
3.3
3.0
10.21
9.86
g/l
0.21
25
150
16
89
1.86
1.41
1.3
1.4
8.33
8.90
u/l
0.07
11
72
11
53
2.13
1.41
11.5
5.1
—
—
—
0
0
64
498
1.39
1.40
2.5
2.6
—
—
—
0
0
38
268
1.50
1.39
1.3
1.6
411.50
441.26
pmol/l
0.34
32
243
23
144
1.66
1.38
2.6
2.2
10.81
12.77
nmol/l
0.40
18
134
6
23
2.65
1.37
1.0
1.3
—
—
—
0
0
14
75
1.92
1.37
12.3
7.6
94.78
93.63
%
0.43
14
75
202
1885
1.48
1.35
4.4
4.1
2.86
2.88
mmol/l
0.11
194
1790
200
1864
1.47
1.33
4.3
3.8
4.74
4.79
mmol/l
0.34
193
1779
6
132
0.44
1.33
1.3
1.4
—
—
—
0
0
14
76
1.89
1.33
1.7
3.4
21.67
22.16
s
—
9
68
19
114
1.72
1.33
1.2
1.2
—
—
—
0
0
6
24
2.54
1.31
1.3
2.6
—
813.40
—
0
10
157
1414
1.33
1.25
6.6
6.7
69.73
77.38
u/l
2.32
150
1331
93
780
1.32
1.24
5.9
6.8
1.22
1.22
mmol/l
0.25
81
677
8
37
2.20
1.22
1.5
1.4
—
—
—
0
0
193
1797
1.40
1.20
3.8
3.6
5.54
5.73
mmol/l
1.64
187
1688
31
220
1.47
1.12
1.4
1.6
1082.38
1210.19
nmol/l
0.41
21
173
180
1665
1.34
1.11
4.3
4.4
36.50
38.49
mmol/mol
3.70
171
1591
67
544
1.32
1.11
2.3
2.7
17.17
57.66
e6/l
1.63
50
412
13
74
1.80
1.09
1.3
1.1
—
—
—
0
0
57
454
1.34
1.07
2.2
2.0
141.00
139.82
u/l
0.01
57
433
7
33
2.15
1.06
1.0
1.0
—
—
—
0
0
114
998
1.27
1.06
4.8
4.1
6.05
6.38
mmol/l
1.53
109
908
68
558
1.31
1.04
2.3
3.0
29.59
22.85
ng/l
0.15
39
285
5
22
2.30
1.04
1.8
2.0
—
—
—
0
0
5
22
2.30
1.04
1.8
2.0
—
—
—
0
0
5
22
2.30
1.04
1.8
2.0
—
—
—
0
0
5
22
2.30
1.04
2.0
3.1
1.41
1.38
e9/l
—
5
7
5
22
2.30
1.04
1.8
2.0
—
—
—
0
0
0
29
0.00
0.98
0.0
2.4
—
7.02
—
0
29
0
30
0.00
0.98
0.0
2.4
—
1.28
—
0
30
54
435
1.31
0.94
1.6
1.7
—
—
—
0
0
13
79
1.68
0.90
14.2
8.1
23.35
24.47
mmol/l
0.55
13
72
61
503
1.29
0.90
1.5
1.4
2.29
2.06
g/l
0.42
41
310
50
402
1.31
0.89
2.5
2.1
2.95
2.96
mg/l
0.01
45
345
17
112
1.56
0.87
1.4
1.4
—
—
—
0
0
194
1835
1.32
0.86
16.0
13.5
332.70
333.27
g/l
0.40
194
1828
0
27
0.00
0.78
0.0
1.0
—
—
—
0
0
29
221
1.36
0.74
1.7
2.5
30.12
29.27
s
0.26
29
216
7
38
1.87
0.74
1.6
1.8
—
—
—
0
0
59
497
1.25
0.73
2.5
2.3
—
—
—
0
0
5
25
2.02
0.73
1.2
3.3
—
—
—
0
0
86
756
1.22
0.72
1.9
1.8
—
—
—
0
0
65
556
1.23
0.70
1.8
2.0
—
—
—
0
0
7
41
1.73
0.70
1.4
1.8
—
—
—
0
0
5
27
1.87
0.69
1.6
1.0
—
—
—
0
0
19
137
1.42
0.67
8.7
8.0
—
—
—
0
0
5
28
1.80
0.66
1.0
1.3
—
—
—
0
0
27
208
1.34
0.65
2.5
2.6
0.53
0.69
ug/l
1.14
18
118
16
112
1.46
0.65
1.1
1.1
—
—
—
0
0
64
551
1.22
0.65
1.5
1.3
1.13
1.45
u/ml
0.27
19
136
42
345
1.26
0.65
1.7
1.7
—
—
—
0
0
99
892
1.19
0.62
7.0
6.1
0.79
0.68
%
1.51
94
845
216
2094
1.36
0.62
10.1
8.8
25.98
26.25
u/l
0.06
209
2041
8
50
1.62
0.62
1.1
2.3
327.63
190.43
e6/l
—
8
42
8
50
1.62
0.62
1.1
2.2
1.88
2.82
e6/l
—
8
39
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
44
367
1.24
0.60
1.3
1.3
14.51
21.95
iu/ml
0.79
17
117
0
22
0.00
0.59
0.0
19.4
—
1630.32
—
0
22
0
22
0.00
0.59
0.0
14.1
—
828.00
—
0
22
18
132
1.39
0.59
1.9
1.9
1.39
1.47
g/l
0.09
18
125
8
53
1.53
0.59
5.8
7.5
—
—
—
0
0
21
159
1.35
0.57
2.7
2.9
—
—
—
0
0
40
332
1.25
0.57
2.2
2.3
511.42
588.01
mosm/kgh2o
0.95
31
290
19
142
1.37
0.56
14.9
13.9
—
1.16
—
0
26
207
2002
1.27
0.55
11.2
10.2
18.98
19.68
mg/l
0.09
153
1498
55
475
1.21
0.55
3.4
3.7
7.40
7.40
ph
—
7
79
103
940
1.17
0.54
7.4
6.3
8.24
8.05
%
0.31
98
897
102
931
1.17
0.54
7.1
6.0
3.23
2.80
%
1.04
97
879
6
40
1.51
0.52
1.0
1.3
—
—
—
0
0
64
564
1.18
0.51
2.2
2.4
—
—
—
0
0
105
965
1.16
0.50
6.8
5.8
53.48
56.07
%
1.64
99
920
230
2264
1.54
0.50
17.5
15.6
30.08
30.08
pg
0.02
230
2244
230
2264
1.54
0.50
17.5
15.7
90.09
90.06
fl
0.03
230
2244
28
228
1.26
0.48
1.5
1.2
—
—
—
0
0
21
165
1.30
0.47
1.4
1.5
—
—
—
0
0
15
112
1.36
0.46
12.5
7.9
124.93
123.55
g/l
0.09
15
107
69
618
1.16
0.46
7.2
6.1
—
—
—
0
0
11
78
1.43
0.44
2.6
2.7
—
—
—
0
0
18
141
1.30
0.41
10.8
6.9
4.82
5.13
kpa
0.66
18
133
18
141
1.30
0.41
11.1
6.8
12.51
13.36
kpa
0.29
18
134
18
141
1.30
0.41
10.9
6.9
0.76
1.44
mmol/l
0.29
13
107
5
33
1.53
0.41
2.6
2.3
62.20
110.96
ug/min
—
5
18
0
16
0.00
0.41
0.0
3.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
230
2266
1.51
0.40
17.7
15.8
137.06
136.57
g/l
0.23
230
2244
0
18
0.00
0.40
0.0
2.7
—
105.61
—
0
18
0
18
0.00
0.40
0.0
1.1
—
1.20
—
0
13
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
2.7
—
3.99
—
0
18
0
18
0.00
0.40
0.0
2.7
—
—
—
0
0
14
106
1.34
0.40
2.6
4.8
5.00
5.07
kpa
0.12
14
97
24
197
1.24
0.39
1.8
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
25
299
0.82
0.38
1.3
1.4
—
—
—
0
0
5
36
1.40
0.38
1.4
4.4
15.58
27.08
mg/l
—
5
30
16
125
1.30
0.38
11.9
7.3
96.15
95.88
%
0.08
16
119
216
2115
1.24
0.37
9.7
9.4
—
—
—
0
0
6
42
1.44
0.36
1.2
2.5
—
—
—
0
0
41
361
1.16
0.34
1.3
1.3
1.15
9.25
u/ml
2.39
23
147
6
86
0.69
0.33
1.5
1.2
—
—
—
0
0
46
410
1.15
0.33
2.2
3.0
—
—
—
0
0
104
977
1.11
0.33
7.1
6.0
31.77
30.11
%
0.84
98
931
190
1950
0.87
0.33
12.2
11.3
40.89
40.39
%
0.50
153
1605
18
218
0.81
0.32
1.2
1.2
—
—
—
0
0
7
53
1.33
0.31
1.6
2.8
0.85
1.26
g/l
—
7
46
7
53
1.33
0.31
4.0
4.0
10.19
8.85
kpa
—
7
48
8
66
1.22
0.27
2.0
1.6
—
—
—
0
0
9
74
1.22
0.25
2.1
2.2
—
—
—
0
0
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
5
41
1.22
0.22
1.0
1.2
—
—
—
0
0
15
126
1.20
0.21
1.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.5
—
—
—
0
0
84
797
1.08
0.21
2.3
2.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
122.74
—
0
14
0
14
0.00
0.20
0.0
5.8
—
12.21
—
0
14
45
415
1.10
0.20
1.8
1.9
0.88
0.78
mg/l
0.18
34
311
6
51
1.18
0.19
1.3
1.5
—
—
—
0
0
25
278
0.89
0.18
2.7
2.7
2.46
3.38
e6/l
0.19
12
140
12
101
1.20
0.17
1.1
1.4
—
—
—
0
0
8
71
1.13
0.16
1.6
1.6
—
—
—
0
0
27
245
1.12
0.16
1.7
1.9
—
—
—
0
0
46
491
0.92
0.16
1.6
1.7
1.45
1.42
mmol/l
0.05
37
436
8
73
1.10
0.16
6.0
3.5
1.11
1.34
%
—
8
73
6
79
0.75
0.15
1.7
2.7
—
—
—
0
0
137
1406
0.94
0.15
2.9
3.0
38.67
38.79
u/l
0.01
131
1350
9
81
1.12
0.15
2.8
4.9
—
—
—
0
0
30
326
0.91
0.15
1.4
1.5
—
—
—
0
0
65
619
1.07
0.14
1.6
1.6
—
—
—
0
0
38
355
1.08
0.13
3.7
4.0
—
—
—
0
0
18
161
1.13
0.13
2.7
2.3
—
14.14
—
0
8
16
142
1.14
0.13
1.4
1.3
—
33.32
—
0
8
16
144
1.12
0.10
1.6
1.5
—
—
—
0
0
16
145
1.11
0.09
1.6
1.5
—
—
—
0
0
16
145
1.11
0.09
1.6
1.5
—
—
—
0
0
16
145
1.11
0.09
1.6
1.5
—
—
—
0
0
56
538
1.05
0.09
1.9
2.0
—
—
—
0
0
5
64
0.78
0.08
19.4
7.6
—
—
—
0
0
6
71
0.84
0.08
1.3
1.2
—
—
—
0
0
6
70
0.85
0.08
1.2
1.1
—
—
—
0
0
9
84
1.07
0.07
1.1
1.4
—
—
—
0
0
9
84
1.07
0.07
1.1
1.4
—
—
—
0
0
26
275
0.94
0.07
2.1
3.0
521.60
165.99
ng/l
0.31
20
165
9
87
1.04
0.07
1.0
1.6
—
9.23
—
0
6
9
87
1.04
0.07
1.2
1.6
—
—
—
0
0
176
1777
0.96
0.06
12.8
12.9
13.34
13.39
%
0.21
176
1756
37
385
0.95
0.06
2.5
3.2
18.80
265.52
mg/l
0.72
21
251
39
404
0.96
0.05
2.6
3.9
3.02
12.12
mg/mmol
2.07
20
263
19
180
1.06
0.04
1.4
1.4
—
—
—
0
0
12
112
1.08
0.03
2.2
2.0
—
—
—
0
0
12
127
0.94
0.01
1.0
1.1
—
—
—
0
0
15
157
0.95
0.01
4.9
6.3
—
—
—
0
0
13
136
0.95
0.00
2.0
4.3
—
—
—
0
0
57
564
1.01
0.00
5.0
5.4
1.12
1.09
inr
0.10
17
175
22
217
1.02
0.00
1.2
1.2
—
—
—
0
0
11
114
0.96
0.00
1.5
1.5
—
—
—
0
0
13
134
0.97
0.00
1.4
1.5
—
—
—
0
0
18
176
1.02
0.00
1.1
1.2
93.16
121.71
iu/ml
—
5
68
49
492
0.99
0.00
2.3
3.3
7.98
8.06
mmol/l
0.04
44
429
11
105
1.05
0.00
7.7
6.5
23.78
25.23
mmol/l
0.63
11
105
10
105
0.95
0.00
1.6
1.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
13.90
—
0
5
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
44.20
—
0
5
0
8
0.00
0.00
0.0
9.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
5.8
—
3.50
—
0
5
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
54
0.92
0.00
1.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
165.60
—
0
5
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
19.05
—
0
6

Mortality – FinRegistry

↥

Association

Association between endpoint K11_MANDIBULAR_HYPOPL and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_MANDIBULAR_HYPOPL.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: K11_MANDIBULAR_HYPOPL – Mandibular hypoplasia

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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