Mandibular hypoplasia

K11_MANDIBULAR_HYPOPL

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K07.04
  • Hospital discharge: ICD-10 K07.04
  • Cause of death: ICD-10 K07.04

3 out of 7 registries used, show all original rules.

248

4. Check minimum number of events

None

248

5. Include endpoints

None

248

6. Filter based on genotype QC (FinnGen only)

240

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3002 1649 1349
Only index persons 2772 1531 1241
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.04
Only index persons 0.05 0.06 0.05
Median age at first event (years)
Whole population 16.04 18.26 13.29
Only index persons 17.29 20.04 13.90

-FinnGen-

Key figures

All Female Male
Number of individuals 240 174 66
Unadjusted period prevalence (%) 0.05 0.06 0.03
Median age at first event (years) 37.65 36.39 40.97

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
248
Matched controls
2480
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
+∞
307.7
248
*
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
156.0
191.7
96
10
K07.13
ICD-10 Finland
Retrognaty, mandibular
92.4
185.0
100
18
K07.23
ICD-10 Finland
Deep bite
27.0
111.4
85
47
SBB10
NOMESCO Finland
Dental impressions
14.8
102.0
125
159
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
21.4
92.0
77
51
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
25.6
89.9
68
36
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
19.2
89.6
80
60
EB1MA
NOMESCO Finland
Cephalometry with X-ray
19.9
88.4
77
55
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
15.0
76.6
79
75
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
17.3
74.9
69
54
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
19.8
73.4
62
41
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
25.3
59.8
44
21
K07.24
ICD-10 Finland
Open bite
28.7
58.7
41
17
SAA04
NOMESCO Finland
Special examination of mouth
11.1
58.4
73
90
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
25.7
56.3
41
19
SJC10
NOMESCO Finland
Orthodontic band in one tooth
14.1
54.6
55
49
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
16.4
49.8
45
33
K07.60
ICD-10 Finland
Snapping jaw
8.9
43.8
63
91
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
12.9
43.0
45
42
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
10.7
43.0
52
60
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
10.7
39.4
47
53
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
13.1
39.0
40
36
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
8.3
38.4
58
88
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
11.1
34.2
39
41
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
6.4
32.9
65
130
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
8.7
30.3
42
57
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
5.0
29.0
81
219
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
8.4
28.9
41
57
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
8.6
27.5
38
51
K07.4
ICD-10 Finland
Malocclusion, unspecified
9.6
26.4
33
39
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
7.8
23.6
35
51
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
+∞
23.3
22
*
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
48.2
21.9
26
6
EEC05
NOMESCO Finland
Le Fort I osteotomy
120.2
20.9
22
*
K07.10
ICD-10 Finland
Asymmetry of jaw
120.2
20.9
22
*
SXC05
NOMESCO Finland
Other oral or dental procedure
4.7
20.0
54
139
WZC00
NOMESCO Finland
Treatment plan or consultation
3.3
19.5
133
639
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
42.0
18.9
23
6
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
5.6
18.5
38
77
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
5.9
18.1
35
67
SAA03
NOMESCO Finland
Extended examination of mouth
3.1
16.8
152
838
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
13.0
16.5
29
25
K07.0
ICD-10 Finland
Major anomalies of jaw size
170.3
15.7
16
*
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
60.5
15.0
17
*
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
27.0
14.9
20
8
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
85.3
14.7
16
*
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
6.9
14.4
23
36
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
5.4
14.0
29
59
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.7
13.6
143
822
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
4.1
13.4
40
110
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
5.0
13.0
30
67
EBB10
NOMESCO Finland
Insertion of dental implant
18.6
12.7
19
11
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
73.7
12.7
14
*
EDC30
NOMESCO Finland
Genioplasty
+∞
12.6
12
*
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
39.7
12.3
15
*
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
17.5
11.9
18
11
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
20.2
11.8
17
9
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
+∞
10.5
10
*
Z47.0
ICD-10 Finland
Follow-up care involving removal of fracture plate and other internal fixation device
41.9
10.1
12
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.9
10.0
31
87
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
10.2
10.0
19
20
K07.14
ICD-10 Finland
Retrognaty, maxillary
57.3
9.7
11
*
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
4.6
9.6
24
57
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
103.8
9.5
10
*
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
103.8
9.5
10
*
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
103.8
9.5
10
*
EBB15
NOMESCO Finland
Insertion of dental implant abutment
22.7
9.4
13
6
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
38.2
9.1
11
*
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
38.2
9.1
11
*
K01.0
ICD-10 Finland
Embedded teeth
8.5
9.0
19
24
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
12.2
8.7
15
13
SPC20
NOMESCO Finland
Implant borne crown
28.6
8.6
11
*
5240A
ICD-9 Finland
Dentofacial anomalies, including malocclusion, Major anomalies of jaw size
93.1
8.5
9
*
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
34.6
8.1
10
*
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
46.5
7.8
9
*
4343
FHL
Lower jaw open osteotomy
82.5
7.5
8
*
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
9.8
7.4
14
15
EDC45
NOMESCO Finland
Reconstruction of mandible using bone graft
+∞
7.3
7
*
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.7
7.3
45
191
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
7.7
7.3
16
22
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
7.3
100
601
ZXA10
NOMESCO Finland
Bilateral
2.5
7.2
51
232
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
7.4
7.1
16
23
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.9
6.9
21
58
P01BA02
ATC
hydroxychloroquine; oral
3.2
6.9
28
94
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
6.2
6.7
17
29
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
23.2
6.7
9
*
L01BA01
ATC
methotrexate; systemic
7.2
6.6
15
22
G47.3
ICD-10 Finland
Sleep apnoea
2.3
6.5
60
306
K07.9
ICD-10 Finland
Dentofacial anomaly, unspecified
71.6
6.5
7
*
K07.00
ICD-10 Finland
Macrognatia (hyperplasia) of the upper jaw
+∞
6.3
6
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.4
6.0
22
69
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
6.0
92
568
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
7.6
6.0
13
18

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
37
119
3.48
9.81
3.8
3.7
—
—
—
0
0
93
500
2.38
9.33
3.9
3.2
0.00
0.01
estimate
0.50
30
199
124
816
2.04
7.01
3.4
2.9
5.62
5.82
ph
0.18
13
89
143
993
2.04
6.94
3.5
3.0
0.00
0.00
estimate
0.50
32
210
204
1625
2.44
6.88
4.9
4.1
14.60
14.51
pmol/l
0.23
186
1500
75
427
2.08
6.15
4.1
3.3
—
—
—
0
0
139
996
1.90
5.74
4.4
4.3
0.00
0.00
estimate
0.50
32
200
139
1007
1.87
5.44
3.5
3.1
0.00
0.00
estimate
-0.00
30
191
71
431
1.91
4.72
4.3
3.2
1.02
1.02
kg/l
—
9
58
8
13
6.32
3.53
1.9
1.4
—
—
—
0
0
217
1925
2.02
3.38
5.6
4.6
1.75
1.78
mu/l
0.18
202
1806
34
187
1.95
2.97
1.2
1.4
—
—
—
0
0
157
1298
1.57
2.91
3.5
3.1
—
—
—
0
0
35
204
1.83
2.58
1.5
1.3
—
—
—
0
0
234
2177
2.33
2.53
11.3
11.5
69.00
70.36
umol/l
0.69
234
2177
209
1878
1.72
2.50
4.0
3.4
1.22
1.26
mmol/l
0.39
202
1774
122
982
1.48
2.38
6.8
6.6
—
—
—
0
0
128
1041
1.47
2.37
6.8
6.1
0.51
0.54
e9/l
0.65
117
922
36
218
1.76
2.35
1.6
1.5
—
—
—
0
0
51
341
1.62
2.32
1.5
1.5
20.77
21.76
nmol/l
0.25
46
294
29
165
1.86
2.31
1.4
1.7
—
—
—
0
0
17
80
2.21
2.24
1.2
1.4
—
—
—
0
0
127
1039
1.46
2.24
6.8
6.1
0.04
0.04
e9/l
0.88
115
920
44
286
1.65
2.23
1.4
1.6
421.55
441.10
pmol/l
0.21
38
259
89
681
1.48
2.21
2.9
3.3
22.95
61.37
e6/l
0.71
63
470
130
1071
1.45
2.19
6.8
6.7
0.20
0.18
e9/l
0.42
118
966
131
1082
1.45
2.17
6.8
6.1
1.92
2.05
e9/l
0.49
120
980
144
1211
1.45
2.17
7.5
9.5
3.74
3.91
e9/l
0.42
128
1063
39
250
1.66
2.09
1.4
2.5
17.69
14.77
umol/l
0.96
39
236
38
242
1.67
2.09
2.2
1.9
—
—
—
0
0
5
10
5.08
2.08
1.0
1.5
—
—
—
0
0
7
20
3.57
2.07
1.0
1.5
—
—
—
0
0
116
943
1.43
2.07
7.7
8.2
0.00
0.00
e9/l
0.75
105
775
55
385
1.55
2.06
1.9
2.2
4.90
8.37
e6/l
0.70
48
349
171
1497
1.46
2.00
4.6
3.8
6.98
9.26
mm/h
3.46
158
1404
76
575
1.46
1.97
2.2
3.3
2.36
2.36
mmol/l
0.27
70
524
13
59
2.27
1.87
1.9
2.4
2.33
8.69
umol/l
—
8
42
158
1373
1.42
1.86
3.9
3.7
—
—
—
0
0
24
139
1.80
1.83
2.1
2.4
7144.19
2899.93
u/l
—
10
56
5
12
4.23
1.83
1.0
1.3
—
—
—
0
0
69
519
1.46
1.83
2.4
2.8
0.23
0.34
e6/l
0.38
53
391
121
1012
1.38
1.74
2.9
2.9
60.70
86.67
ug/l
4.17
115
954
81
634
1.41
1.72
1.8
1.8
99.28
95.95
pmol/l
0.29
48
338
211
1948
1.56
1.71
4.3
3.8
1.53
1.49
mmol/l
0.54
204
1847
10
40
2.56
1.68
1.2
1.3
3.40
6.28
u/ml
—
5
18
68
519
1.43
1.66
5.0
7.2
—
—
—
0
0
92
741
1.38
1.65
5.7
5.8
1.21
1.22
mmol/l
0.54
86
689
10
42
2.44
1.63
1.0
1.1
—
—
—
0
0
213
1976
1.55
1.62
4.5
4.1
2.84
2.87
mmol/l
0.20
206
1876
35
234
1.58
1.61
1.7
1.6
1114.32
1210.01
nmol/l
0.29
25
184
21
122
1.79
1.60
1.2
1.2
—
—
—
0
0
211
1956
1.53
1.58
4.4
3.8
4.74
4.78
mmol/l
0.28
204
1865
6
140
0.41
1.58
1.3
1.4
—
—
—
0
0
15
78
1.98
1.58
1.3
1.2
—
—
—
0
0
27
170
1.66
1.57
2.8
2.8
—
—
—
0
0
27
170
1.66
1.57
3.2
2.9
10.35
9.86
g/l
0.34
27
161
8
33
2.47
1.55
2.4
1.2
—
—
—
0
0
68
526
1.40
1.53
2.5
2.7
—
—
—
0
0
204
1885
1.46
1.49
3.9
3.6
5.60
5.73
mmol/l
0.69
198
1768
73
575
1.38
1.48
2.3
2.8
16.12
55.06
e6/l
1.70
56
439
17
95
1.85
1.47
1.3
1.5
9.37
9.12
u/l
0.03
12
77
45
325
1.47
1.46
2.6
2.2
111.49
88.53
ug/g
0.30
35
262
99
825
1.33
1.38
5.7
6.8
1.21
1.22
mmol/l
0.32
86
717
41
295
1.47
1.36
1.6
1.6
—
—
—
0
0
6
24
2.54
1.31
1.0
1.3
—
—
—
0
0
15
84
1.84
1.30
6.4
5.3
—
—
—
0
0
190
1748
1.37
1.30
4.6
4.4
36.84
38.43
mmol/mol
2.09
181
1670
11
56
2.01
1.24
11.5
5.3
—
—
—
0
0
14
78
1.84
1.24
1.7
3.3
21.67
22.14
s
—
9
70
8
37
2.20
1.22
1.5
1.4
—
—
—
0
0
12
64
1.92
1.20
1.2
1.2
3.23
1.86
u/ml
—
7
42
14
79
1.82
1.19
12.3
7.7
94.78
93.76
%
0.38
14
79
121
1055
1.29
1.17
4.9
4.1
6.12
6.37
mmol/l
0.95
116
958
33
236
1.46
1.14
1.6
2.4
29.80
29.29
s
0.16
33
231
72
597
1.29
1.01
2.3
3.0
27.77
22.89
ng/l
0.12
43
312
7
35
2.03
1.01
1.0
1.0
—
—
—
0
0
60
486
1.31
1.00
2.1
2.0
139.97
169.73
u/l
0.32
60
463
5
23
2.20
0.98
2.0
3.0
1.41
1.42
e9/l
—
5
18
0
29
0.00
0.98
0.0
2.4
—
7.02
—
0
29
0
29
0.00
0.98
0.0
1.1
—
—
—
0
0
0
30
0.00
0.98
0.0
2.4
—
1.28
—
0
30
25
175
1.48
0.97
9.8
6.4
105.16
104.13
mmol/l
0.46
25
175
162
1485
1.26
0.96
6.6
6.8
69.97
77.05
u/l
2.13
154
1396
57
462
1.30
0.94
1.6
1.7
—
—
—
0
0
14
86
1.67
0.93
13.4
8.1
23.33
24.82
mmol/l
0.89
14
80
64
529
1.28
0.92
1.5
1.4
2.30
2.07
g/l
0.50
44
329
71
598
1.26
0.87
2.3
2.5
—
—
—
0
0
28
207
1.40
0.84
1.7
1.4
—
—
—
0
0
52
426
1.28
0.80
2.5
2.1
2.93
2.94
mg/l
0.01
47
367
64
538
1.26
0.80
2.4
2.3
—
—
—
0
0
0
24
0.00
0.79
0.0
18.8
—
1548.33
—
0
24
20
141
1.46
0.77
1.9
1.9
1.38
1.45
g/l
0.09
20
133
227
2194
1.41
0.75
10.1
8.8
25.72
26.13
u/l
0.11
220
2138
9
55
1.66
0.74
6.0
7.5
—
—
—
0
0
31
239
1.34
0.73
1.5
1.2
—
—
—
0
0
5
25
2.02
0.73
1.6
1.0
219.00
309.60
pmol/l
—
5
25
17
118
1.47
0.71
1.4
1.4
—
—
—
0
0
218
2099
1.32
0.70
10.9
10.4
18.98
19.64
mg/l
0.08
161
1575
90
796
1.21
0.69
2.0
1.8
—
—
—
0
0
44
361
1.27
0.68
2.2
2.4
509.20
570.16
mosm/kgh2o
0.82
35
317
7
43
1.65
0.67
1.4
1.8
—
—
—
0
0
7
43
1.65
0.67
1.6
2.2
—
—
—
0
0
59
502
1.23
0.66
3.4
3.8
7.39
7.40
ph
—
10
85
5
28
1.80
0.66
1.2
3.0
—
—
—
0
0
27
208
1.33
0.65
2.5
2.6
0.53
0.69
ug/l
1.14
18
118
5
29
1.74
0.64
1.0
1.3
—
—
—
0
0
200
1913
1.23
0.62
15.8
13.7
332.79
333.21
g/l
0.28
200
1905
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
46
386
1.24
0.59
1.4
1.3
14.14
23.95
iu/ml
1.17
18
124
19
141
1.38
0.58
8.7
8.0
—
—
—
0
0
51
434
1.22
0.58
2.1
3.1
—
—
—
0
0
6
36
1.68
0.57
2.3
3.7
23.97
24.07
mmol/l
—
6
36
8
55
1.47
0.56
1.1
2.1
1.88
2.79
e6/l
—
8
43
8
55
1.47
0.56
1.1
2.2
327.63
177.78
e6/l
—
8
46
44
370
1.23
0.56
1.7
1.7
—
—
—
0
0
6
38
1.59
0.54
4.5
4.2
58.83
57.87
%
—
6
38
6
38
1.59
0.54
4.5
3.6
3.74
4.76
e9/l
—
6
38
67
590
1.19
0.54
1.8
2.0
—
—
—
0
0
16
117
1.39
0.53
1.1
1.1
—
—
—
0
0
103
940
1.16
0.53
6.8
6.1
0.80
0.68
%
1.86
97
889
66
583
1.18
0.51
1.6
1.3
1.05
1.38
u/ml
0.32
21
148
241
2373
1.55
0.50
17.5
16.1
136.99
136.32
g/l
0.36
241
2349
241
2371
1.58
0.49
17.4
15.9
90.15
90.08
fl
0.09
241
2349
241
2371
1.58
0.49
17.4
15.9
30.11
30.09
pg
0.08
241
2349
25
306
0.80
0.46
1.3
1.4
—
—
—
0
0
5
31
1.63
0.43
1.6
1.0
—
—
—
0
0
227
2220
1.27
0.43
9.8
9.6
—
—
—
0
0
106
983
1.14
0.42
6.9
6.0
3.21
2.81
%
0.94
100
931
107
993
1.14
0.42
7.1
6.3
8.22
8.07
%
0.24
101
945
17
132
1.31
0.41
1.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
5.5
—
12.27
—
0
15
0
16
0.00
0.41
0.0
1.1
—
157.52
—
0
16
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
3.4
—
—
—
0
0
0
18
0.00
0.40
0.0
2.7
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
220.30
—
0
18
0
18
0.00
0.40
0.0
2.7
—
3.99
—
0
18
0
18
0.00
0.40
0.0
2.7
—
105.61
—
0
18
0
18
0.00
0.40
0.0
1.1
—
1.20
—
0
13
19
151
1.28
0.40
10.4
6.9
0.82
1.47
mmol/l
0.30
14
119
17
133
1.30
0.39
11.2
7.2
96.08
95.89
%
0.06
17
127
46
520
0.86
0.38
1.6
1.7
1.45
1.42
mmol/l
0.06
37
457
109
1019
1.12
0.38
6.5
5.8
53.66
56.00
%
1.46
103
971
19
233
0.80
0.36
1.1
1.2
—
—
—
0
0
6
41
1.47
0.36
1.0
1.2
—
—
—
0
0
6
45
1.34
0.34
1.2
2.4
—
—
—
0
0
43
382
1.15
0.32
1.4
1.3
1.14
8.60
u/ml
2.40
25
160
11
84
1.32
0.30
2.6
2.5
—
—
—
0
0
240
2371
1.38
0.29
17.6
15.9
40.92
40.56
%
0.59
234
2261
7
57
1.23
0.29
1.6
2.8
0.85
1.32
g/l
—
7
50
14
112
1.26
0.29
2.6
4.7
5.00
5.08
kpa
0.13
14
106
21
177
1.20
0.28
1.4
1.5
—
—
—
0
0
18
151
1.21
0.26
10.8
6.8
4.82
5.17
kpa
0.77
18
143
18
151
1.21
0.26
11.1
6.8
12.51
13.29
kpa
0.26
18
144
9
73
1.24
0.25
1.7
1.7
—
—
—
0
0
31
347
0.88
0.24
1.4
1.5
—
—
—
0
0
5
39
1.29
0.23
1.4
4.1
15.58
25.85
mg/l
—
5
33
5
40
1.26
0.22
1.0
1.1
—
—
—
0
0
29
258
1.14
0.22
1.8
1.9
—
—
—
0
0
5
41
1.22
0.22
1.0
1.2
—
—
—
0
0
108
1033
1.08
0.21
6.9
6.0
31.21
30.14
%
0.45
102
986
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
26
292
0.88
0.21
2.7
2.8
2.27
3.24
e6/l
0.22
13
149
0
13
0.00
0.21
0.0
2.5
—
35676.92
—
0
13
10
80
1.26
0.21
2.2
2.2
—
—
—
0
0
47
436
1.10
0.19
1.8
1.9
0.85
0.78
mg/l
0.11
36
328
17
148
1.16
0.17
1.6
1.5
—
—
—
0
0
17
148
1.16
0.17
1.4
1.3
—
33.32
—
0
8
87
832
1.07
0.17
2.4
2.4
—
—
—
0
0
5
68
0.73
0.17
19.4
7.6
—
—
—
0
0
19
168
1.14
0.16
2.6
2.3
—
23.01
—
0
10
17
149
1.15
0.16
1.6
1.5
—
—
—
0
0
17
149
1.15
0.16
1.6
1.5
—
—
—
0
0
17
149
1.15
0.16
1.6
1.5
—
—
—
0
0
8
72
1.11
0.16
6.0
3.6
0.63
0.65
%
—
8
72
8
73
1.10
0.16
2.0
1.6
—
—
—
0
0
69
659
1.07
0.14
1.6
1.6
—
—
—
0
0
73
700
1.06
0.13
7.9
7.8
1.09
1.11
inr
0.05
19
218
13
148
0.87
0.13
2.0
4.2
—
—
—
0
0
13
115
1.14
0.10
2.2
2.0
—
—
—
0
0
144
1466
0.96
0.10
2.9
3.0
38.27
38.31
u/l
0.00
138
1408
5
46
1.09
0.09
2.2
1.7
—
—
—
0
0
188
1902
0.95
0.09
12.8
12.9
13.62
14.16
%
1.50
188
1883
12
134
0.89
0.09
1.0
1.1
—
—
—
0
0
6
56
1.07
0.08
1.3
1.5
—
—
—
0
0
27
287
0.93
0.08
2.0
3.1
521.60
216.20
ng/l
0.26
20
176
40
382
1.06
0.08
3.6
4.0
—
—
—
0
0
6
72
0.83
0.07
1.3
1.2
—
—
—
0
0
6
72
0.83
0.07
1.2
1.1
—
—
—
0
0
8
75
1.07
0.07
6.0
3.5
1.11
1.34
%
—
8
75
7
83
0.84
0.07
1.6
2.6
—
—
—
0
0
9
86
1.05
0.07
2.8
4.6
—
—
—
0
0
8
90
0.89
0.07
2.6
1.2
—
—
—
0
0
12
109
1.11
0.06
1.1
1.4
—
—
—
0
0
59
574
1.04
0.06
1.8
2.0
—
—
—
0
0
53
515
1.04
0.05
2.3
3.3
8.21
8.01
mmol/l
0.11
48
456
15
160
0.93
0.04
4.9
6.3
—
—
—
0
0
42
429
0.97
0.02
2.6
3.7
3.06
11.60
mg/mmol
2.07
23
277
40
407
0.98
0.01
2.5
3.2
19.20
251.43
mg/l
0.72
24
266
10
94
1.07
0.01
1.2
1.4
—
—
—
0
0
10
94
1.07
0.01
1.2
1.4
—
—
—
0
0
11
108
1.02
0.00
7.7
6.6
23.78
25.17
mmol/l
0.60
11
108
19
188
1.01
0.00
1.4
1.4
—
—
—
0
0
11
107
1.03
0.00
1.7
1.8
—
—
—
0
0
10
97
1.03
0.00
1.3
1.5
—
—
—
0
0
12
117
1.03
0.00
1.5
1.5
—
—
—
0
0
22
223
0.99
0.00
1.2
1.2
—
—
—
0
0
14
137
1.02
0.00
1.4
1.5
—
—
—
0
0
18
184
0.98
0.00
1.1
1.2
93.16
141.82
iu/ml
—
5
73
0
5
0.00
-0.00
0.0
7.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
18.59
—
0
7
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
165.60
—
0
5
0
5
0.00
-0.00
0.0
5.8
—
3.50
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
59
0.84
-0.00
1.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
9.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
13.90
—
0
5
0
9
0.00
-0.00
0.0
9.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
140.33
—
0
8
9
93
0.97
-0.00
1.0
1.6
—
9.23
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
44.20
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
7.67
—
0
9

Mortality – FinRegistry

Association

Association between endpoint K11_MANDIBULAR_HYPOPL and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_MANDIBULAR_HYPOPL.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: K11_MANDIBULAR_HYPOPL – Mandibular hypoplasia

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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