Mandibular prognathia AND surgery (LeFortI or BSSO)

K11_MN_PROGN_AND_SURGRT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

  • OPER_LEFORT1_BSSRO
1698

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K07.11
  • Cause of death: ICD-10 K07.11

2 out of 7 registries used, show all original rules.

189

4. Check minimum number of events

None

189

5. Include endpoints

None

189

6. Filter based on genotype QC (FinnGen only)

177

Control definitions (FinnGen only)

Control exclude
K11_MN_PROGN_AND_SURGRT_INCLAVO

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1251 708 535
Only index persons 1235 701 534
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.01
Only index persons 0.02 0.03 0.02
Median age at first event (years)
Whole population 28.06 27.97 28.18
Only index persons 28.04 27.92 28.20

-FinnGen-

Key figures

All Female Male
Number of individuals 177 113 64
Unadjusted period prevalence (%) 0.04 0.04 0.03
Median age at first event (years) 33.75 34.44 32.52

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
189
Matched controls
1890
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
+∞
273.5
189
*
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
167.4
230.6
119
19
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
184.4
211.5
106
13
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
146.9
208.3
108
17
SJC10
NOMESCO Finland
Orthodontic band in one tooth
191.9
201.5
100
11
SBB10
NOMESCO Finland
Dental impressions
58.8
184.8
136
79
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
116.2
182.5
97
17
EEC05
NOMESCO Finland
Le Fort I osteotomy
5950.7
181.4
145
*
EB1MA
NOMESCO Finland
Cephalometry with X-ray
103.8
178.8
97
19
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
124.4
174.3
91
14
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
66.3
171.0
105
35
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
69.5
171.0
103
32
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
112.4
150.4
79
12
K07.14
ICD-10 Finland
Retrognaty, maxillary
1206.2
124.4
108
*
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
82.0
118.6
65
12
K07.13
ICD-10 Finland
Retrognaty, mandibular
89.6
113.4
61
10
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
531.6
112.0
101
*
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
58.1
102.3
60
15
SAA04
NOMESCO Finland
Special examination of mouth
25.3
94.4
77
50
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
190.7
86.7
85
8
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
165.9
84.5
84
9
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
36.4
77.0
51
19
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
21.0
73.5
63
44
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
31.4
73.1
51
22
SXC05
NOMESCO Finland
Other oral or dental procedure
16.1
65.5
66
61
K07.10
ICD-10 Finland
Asymmetry of jaw
763.4
59.0
55
*
K07.24
ICD-10 Finland
Open bite
96.0
51.4
55
8
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
23.2
46.9
36
19
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
514.2
43.0
41
*
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
+∞
41.2
38
*
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
7.4
39.9
82
178
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
53.4
35.8
42
10
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
57.7
35.4
41
9
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
371.0
31.8
31
*
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
7.6
31.3
53
92
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
+∞
31.1
29
*
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
+∞
30.0
28
*
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
31.4
27.4
36
14
WZC00
NOMESCO Finland
Treatment plan or consultation
5.1
27.1
116
452
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
299.6
26.4
26
*
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
10.2
26.2
32
37
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
+∞
25.6
24
*
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
8.1
25.3
38
57
SAA03
NOMESCO Finland
Extended examination of mouth
4.9
23.4
134
630
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
86.5
21.2
23
*
Z3229
NOMESCO Finland
Other healthcare associate professional
7.1
20.8
35
59
K07.60
ICD-10 Finland
Snapping jaw
6.3
20.4
39
75
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
222.3
20.0
20
*
EBB10
NOMESCO Finland
Insertion of dental implant
39.0
19.4
24
7
ZXE20
NOMESCO Finland
More than three and less than five hours
5.2
18.4
45
108
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
74.1
18.1
20
*
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
27.3
17.8
24
10
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.8
17.6
124
630
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
+∞
16.9
16
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
5.4
16.7
37
81
SXC03
NOMESCO Finland
Other oral or dental procedure
65.9
16.1
18
*
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
+∞
15.8
15
*
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
+∞
15.8
15
*
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
5.6
15.4
32
66
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
29.9
14.6
19
7
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
28.2
13.6
18
7
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
28.2
13.6
18
7
WX408
NOMESCO Finland
General anesthesy, balanced
3.3
12.6
66
267
ZXA10
NOMESCO Finland
Bilateral
3.7
12.6
48
159
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
9.8
12.5
25
29
ZXE30
NOMESCO Finland
More than five and less than seven hours
9.3
11.7
24
29
K07.4
ICD-10 Finland
Malocclusion, unspecified
15.2
11.2
18
13
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
15.2
11.2
18
13
K00.00
ICD-10 Finland
Hypodontia
16.8
11.1
17
11
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
19.3
10.9
16
9
EB1WA, ,
NOMESCO Finland
30.0
10.9
14
5
EBB15
NOMESCO Finland
Insertion of dental implant abutment
34.7
10.5
13
*
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
14.2
10.4
17
13
SPC20
NOMESCO Finland
Implant borne crown
42.5
10.1
12
*
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
21.5
10.0
14
7
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
12.3
9.8
17
15
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
58.1
9.8
11
*
EBA10
NOMESCO Finland
Operative extraction of tooth
2.9
9.3
54
228
K07.23
ICD-10 Finland
Deep bite
9.8
9.3
18
20
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
10.8
8.7
16
16
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
+∞
8.4
8
*
J01CE02
ATC
phenoxymethylpenicillin; oral
2.9
8.0
154
1133
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
14.1
7.5
12
9
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
7.4
7.5
17
25
EEC02
NOMESCO Finland
Rapid expansion of maxilla
+∞
7.3
7
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.7
7.1
17
39
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
4.3
7.1
19
48
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
2.4
7.0
63
326
SPC10
NOMESCO Finland
Standard dental crown
11.6
6.9
12
11
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
23.5
6.7
9
*
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
10.6
6.6
12
12
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
72.2
6.5
7
*
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
72.2
6.5
7
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.8
6.3
36
148
K07.9
ICD-10 Finland
Dentofacial anomaly, unspecified
+∞
6.3
6
*
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
+∞
6.3
6
*
M01AE03
ATC
ketoprofen; systemic, rectal
2.2
6.3
69
386

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
63
422
1.74
3.05
3.0
2.6
—
—
—
0
0
7
13
5.54
2.89
1.0
1.0
—
—
—
0
0
35
213
1.79
2.31
1.5
1.6
461.56
482.60
pmol/l
0.14
27
191
8
26
3.17
2.04
2.0
1.6
13.13
13.38
%
—
8
26
41
275
1.63
1.91
1.6
1.5
—
—
—
0
0
6
17
3.61
1.85
2.8
2.1
6.57
6.64
mmol/l
—
6
17
22
359
0.56
1.78
2.5
2.6
—
—
—
0
0
92
748
1.45
1.73
3.2
3.0
0.00
0.00
estimate
-0.00
12
132
6
19
3.23
1.67
2.8
1.9
1.25
1.19
mmol/l
—
6
19
91
742
1.44
1.67
3.2
3.0
0.00
0.00
estimate
-0.00
13
143
157
1423
1.61
1.67
3.6
3.5
5.60
5.74
mmol/l
0.87
146
1329
59
444
1.48
1.64
1.7
2.1
—
—
—
0
0
56
419
1.48
1.60
2.1
2.4
53.32
54.69
u/l
0.17
56
395
90
737
1.42
1.59
5.0
4.2
0.00
0.00
estimate
-0.00
13
139
178
1676
2.07
1.55
10.4
9.3
—
—
—
0
0
61
770
0.69
1.54
4.0
5.4
0.04
0.04
e9/l
0.06
56
675
78
626
1.42
1.53
2.7
2.2
—
—
—
0
0
133
1176
1.44
1.48
4.1
4.1
14.62
14.53
pmol/l
0.20
122
1096
71
565
1.41
1.45
4.0
6.9
1.24
1.22
mmol/l
1.76
62
493
76
616
1.39
1.38
2.8
2.9
6.12
5.83
ph
—
8
57
6
23
2.66
1.38
6.8
2.9
—
—
—
0
0
0
40
0.00
1.34
0.0
1.2
—
—
—
0
0
8
36
2.28
1.26
2.3
1.5
10.53
21.57
u/l
—
8
31
145
1321
1.42
1.22
4.7
4.4
37.82
38.41
mmol/mol
0.41
136
1263
55
432
1.39
1.18
2.2
2.6
86.25
35.29
ng/l
0.35
24
220
36
478
0.70
1.15
3.0
3.2
54.62
39.37
e6/l
0.21
25
310
118
1048
1.34
1.11
3.8
3.8
—
—
—
0
0
157
1462
1.44
1.06
10.4
13.2
335.18
333.75
g/l
1.49
157
1456
44
340
1.38
1.04
2.7
3.1
1.02
1.02
kg/l
—
9
41
61
733
0.75
1.03
4.7
5.8
—
—
—
0
0
29
392
0.69
1.02
2.8
2.7
42.89
40.79
e6/l
0.03
24
295
150
1396
1.36
0.93
4.6
4.7
1.70
1.77
mu/l
0.36
139
1317
121
1094
1.29
0.92
3.1
3.7
7.88
8.77
mm/h
0.51
116
1014
5
103
0.47
0.92
3.8
13.3
98.42
96.80
%
—
5
98
26
350
0.70
0.89
2.9
2.7
0.94
0.26
e6/l
0.42
21
258
27
361
0.71
0.89
2.3
6.5
—
—
—
0
0
5
98
0.50
0.80
2.2
1.3
—
—
—
0
0
8
48
1.70
0.80
8.1
8.6
—
—
—
0
0
10
160
0.60
0.78
2.7
2.3
0.53
0.67
ug/l
—
5
83
29
220
1.38
0.77
2.2
2.0
—
—
—
0
0
23
169
1.41
0.74
1.2
1.2
—
—
—
0
0
89
791
1.24
0.72
3.3
4.6
6.31
6.44
mmol/l
0.36
79
706
13
85
1.57
0.71
2.7
2.1
—
—
—
0
0
57
661
0.80
0.67
9.0
7.4
0.00
0.00
e9/l
-0.00
50
523
33
409
0.77
0.67
1.5
2.9
2.37
2.35
mmol/l
0.29
28
369
172
1656
1.43
0.67
6.9
8.9
25.73
27.33
u/l
0.67
167
1612
14
200
0.68
0.67
2.9
2.5
3.58
3.41
e6/l
—
6
104
79
884
0.82
0.66
5.6
8.8
3.88
3.91
e9/l
0.04
74
764
165
1580
1.35
0.65
9.4
10.5
19.95
19.59
mg/l
0.06
130
1175
103
938
1.22
0.64
2.6
3.0
—
—
—
0
0
17
122
1.43
0.62
3.2
3.1
—
—
—
0
0
21
158
1.37
0.60
1.4
1.4
—
—
—
0
0
7
111
0.62
0.60
2.4
2.8
0.19
0.23
g/l
—
7
104
28
349
0.77
0.60
2.9
3.0
—
—
—
0
0
15
106
1.45
0.60
1.4
4.3
—
—
—
0
0
56
484
1.22
0.58
7.2
7.2
1.04
1.09
inr
0.76
24
150
160
1537
1.27
0.52
3.9
3.9
2.81
2.87
mmol/l
0.37
153
1450
60
529
1.20
0.50
1.8
1.6
—
—
—
0
0
38
321
1.23
0.49
1.4
1.7
0.66
0.78
mg/l
0.35
29
237
14
104
1.37
0.44
1.3
1.6
—
—
—
0
0
36
306
1.22
0.44
3.4
2.9
—
—
—
0
0
152
1460
1.21
0.44
3.3
3.3
1.25
1.29
mmol/l
0.27
146
1375
16
122
1.34
0.44
2.6
2.5
465.66
5890.68
u/l
—
5
55
21
260
0.78
0.44
1.9
2.2
10.52
6.42
e6/l
0.36
21
228
33
387
0.82
0.43
1.7
1.4
1.88
2.19
g/l
0.41
24
243
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
26
215
1.24
0.41
1.6
3.4
9.53
212.64
ng/l
1.41
15
138
0
17
0.00
0.41
0.0
1.9
—
583.41
—
0
17
0
17
0.00
0.41
0.0
19.8
—
1663.18
—
0
17
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
13.6
—
834.82
—
0
17
157
1516
1.21
0.40
3.6
3.6
1.47
1.46
mmol/l
0.11
150
1435
16
124
1.32
0.40
1.3
1.6
—
—
—
0
0
5
35
1.44
0.39
1.2
1.3
—
—
—
0
0
78
717
1.15
0.39
2.7
2.7
80.72
95.51
ug/l
0.44
72
673
9
69
1.32
0.38
1.7
1.3
7.31
9.85
u/l
—
9
60
9
71
1.28
0.36
1.4
1.2
—
—
—
0
0
32
275
1.20
0.36
1.3
1.3
2.04
5.60
u/ml
1.13
16
118
20
163
1.25
0.36
1.2
1.8
—
—
—
0
0
12
155
0.76
0.35
1.1
1.2
—
—
—
0
0
6
46
1.31
0.33
4.5
15.3
1.50
1.59
%
—
6
41
7
100
0.69
0.31
1.4
1.4
—
—
—
0
0
7
100
0.69
0.31
1.4
1.4
—
—
—
0
0
7
53
1.33
0.31
7.7
2.1
—
—
—
0
0
30
262
1.17
0.29
1.4
1.3
—
—
—
0
0
8
63
1.28
0.28
1.0
1.1
—
—
—
0
0
42
379
1.14
0.27
2.9
3.2
0.00
0.01
estimate
0.50
12
137
35
387
0.88
0.23
3.5
2.3
—
—
—
0
0
156
1524
1.14
0.23
3.8
3.6
4.73
4.75
mmol/l
0.10
148
1444
7
93
0.74
0.23
1.0
1.1
—
—
—
0
0
28
314
0.87
0.23
3.0
3.5
2927.68
309.48
mg/l
0.42
17
204
16
135
1.20
0.22
1.4
1.6
—
—
—
0
0
16
135
1.20
0.22
1.4
1.6
—
—
—
0
0
16
135
1.20
0.22
1.4
1.6
—
—
—
0
0
8
103
0.77
0.21
1.6
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
0.98
—
0
10
0
10
0.00
0.21
0.0
1.2
—
7.74
—
0
10
11
89
1.25
0.21
2.1
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
3.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
6.8
—
—
—
0
0
16
136
1.19
0.21
1.4
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
3.1
—
50.00
—
0
5
0
13
0.00
0.21
0.0
2.0
—
—
—
0
0
54
578
0.91
0.20
2.0
1.8
—
—
—
0
0
6
48
1.26
0.20
1.0
1.1
—
—
—
0
0
6
48
1.26
0.20
1.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
617.56
—
0
9
13
109
1.21
0.19
1.2
2.2
4.16
3.95
e9/l
0.12
13
98
6
53
1.14
0.19
2.3
2.1
—
—
—
0
0
30
272
1.12
0.18
1.5
1.5
—
—
—
0
0
30
328
0.90
0.17
3.9
3.8
1.23
13.06
mg/mmol
2.71
18
210
44
471
0.91
0.17
1.7
1.7
111.80
96.93
pmol/l
1.10
26
237
8
72
1.12
0.16
1.5
1.3
—
—
—
0
0
20
178
1.14
0.16
1.6
1.6
—
—
—
0
0
10
119
0.83
0.16
2.6
7.7
104.80
104.79
mmol/l
—
10
119
18
160
1.14
0.14
1.2
1.4
—
—
—
0
0
52
548
0.93
0.14
2.6
2.0
—
—
—
0
0
49
516
0.93
0.13
4.1
4.5
36.95
37.52
g/l
0.34
44
493
38
359
1.07
0.11
2.3
1.7
—
—
—
0
0
15
166
0.90
0.10
1.1
1.2
—
—
—
0
0
12
106
1.14
0.10
1.1
1.2
—
—
—
0
0
5
44
1.14
0.10
1.6
2.1
0.66
0.68
%
—
5
44
10
87
1.16
0.09
1.5
2.2
—
—
—
0
0
30
282
1.08
0.09
1.3
1.3
10.18
27.70
iu/ml
1.96
14
84
5
48
1.04
0.09
1.6
2.1
0.76
1.65
%
—
5
48
17
155
1.11
0.09
2.0
1.6
—
—
—
0
0
6
54
1.11
0.09
2.5
1.8
—
—
—
0
0
5
60
0.83
0.08
1.6
1.5
—
—
—
0
0
17
184
0.92
0.07
1.9
2.3
—
—
—
0
0
45
433
1.05
0.07
1.9
1.7
—
—
—
0
0
9
83
1.09
0.07
2.2
3.7
68.11
69.24
ng/l
—
9
76
10
109
0.91
0.04
1.7
3.9
4.58
4.78
pmol/l
—
10
95
52
509
1.03
0.03
3.1
6.0
1.24
1.22
mmol/l
1.25
45
468
42
430
0.97
0.03
1.4
1.3
0.67
1.17
u/ml
1.12
12
118
11
116
0.95
0.01
1.0
1.7
—
—
—
0
0
10
97
1.03
0.00
1.2
1.2
—
—
—
0
0
38
378
1.01
0.00
1.8
1.7
1.56
1.39
mmol/l
0.47
33
337
28
282
0.99
0.00
5.1
4.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
112.34
—
0
9
0
6
0.00
0.00
0.0
1.8
—
17.42
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
12.7
—
—
—
0
0
0
6
0.00
0.00
0.0
12.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
8.44
—
0
9
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
2.10
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
16
160
1.00
-0.00
1.3
1.3
—
—
—
0
0
9
96
0.93
-0.00
2.6
3.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
1658.71
—
0
7
0
8
0.00
-0.00
0.0
5.0
—
5.46
—
0
8
5
54
0.92
-0.00
2.0
5.9
25.22
24.89
mmol/l
—
5
54
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
59
1.02
-0.00
1.3
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
62
0.97
-0.00
2.5
1.6
28.00
37.61
nmol/l
—
6
62
6
67
0.89
-0.00
3.3
11.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
1.57
—
0
8
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
5.84
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
10.82
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
8.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_MN_PROGN_AND_SURGRT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_MN_PROGN_AND_SURGRT.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: K11_MN_PROGN_AND_SURGRT – Mandibular prognathia AND surgery (LeFortI or BSSO)

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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