This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Mandibular prognathia AND surgery (LeFortI or BSSO), including avohilmo
K11_MN_PROGN_AND_SURGRT_INCLAVO
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
239 |
4. Check minimum number of eventsNone |
239 |
5. Include endpoints |
410 |
6. Filter based on genotype QC (FinnGen only) |
380 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF6
Similar endpoints
↥List of similar endpoints to
Mandibular prognathia AND surgery (LeFortI or BSSO), including avohilmo
based on the number of shared cases.
Similar with more cases:
- Mandibular prognathia
- Dentofacial anomalies [including malocclusion]
- Diseases of oral cavity, salivary glands and jaws
Similar with less cases:
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8708 | 3947 | 4747 |
| Only index persons | 7257 | 3299 | 3958 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.11 | 0.13 |
| Only index persons | 0.14 | 0.12 | 0.15 |
| Median age at first event (years) | |||
| Whole population | 12.20 | 12.16 | 12.17 |
| Only index persons | 13.34 | 13.35 | 13.33 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 380 | 230 | 150 |
| Unadjusted period prevalence (%) | 0.08 | 0.08 | 0.07 |
| Median age at first event (years) | 27.62 | 28.20 | 26.74 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 410
- Matched controls
- 4100
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
+∞
307.7
410
*
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
27.7
239.7
196
131
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
15.9
172.8
197
226
SBB10
NOMESCO Finland
Dental impressions
14.7
171.7
276
505
K07.14
ICD-10 Finland
Retrognaty, maxillary
316.4
164.5
157
8
EEC05
NOMESCO Finland
Le Fort I osteotomy
1157.9
163.5
149
*
EB1MA
NOMESCO Finland
Cephalometry with X-ray
15.2
161.1
182
204
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
16.1
153.4
159
155
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
13.8
151.7
186
233
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
18.9
140.3
125
93
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
13.6
139.3
164
192
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
13.9
138.7
159
179
SJC10
NOMESCO Finland
Orthodontic band in one tooth
13.0
133.6
161
194
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
10.8
117.8
166
243
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
9.8
103.8
154
237
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
228.3
103.7
103
6
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
8.8
101.7
177
327
K07.24
ICD-10 Finland
Open bite
18.9
89.4
75
48
SAA04
NOMESCO Finland
Special examination of mouth
8.3
86.9
146
255
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
12.9
86.9
93
91
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
9.4
81.1
114
161
K07.13
ICD-10 Finland
Retrognaty, mandibular
15.9
79.6
73
55
K07.10
ICD-10 Finland
Asymmetry of jaw
156.8
64.0
66
5
SXC05
NOMESCO Finland
Other oral or dental procedure
5.8
62.9
161
413
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
7.0
59.8
108
198
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
7.6
48.8
77
121
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
5.7
48.2
110
249
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
6.2
48.1
96
192
SAA03
NOMESCO Finland
Extended examination of mouth
5.0
45.2
319
1683
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
245.7
43.8
44
*
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
5.5
42.5
97
218
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
4.7
40.1
116
317
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
6.3
40.0
75
140
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
5.9
39.7
81
164
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.9
37.7
282
1473
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
88.5
36.5
40
5
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
13.7
34.4
33
26
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
4.4
34.3
106
302
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
5.3
33.9
78
175
WZC00
NOMESCO Finland
Treatment plan or consultation
3.5
33.5
241
1197
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
178.9
32.2
33
*
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
123.2
32.2
34
*
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
4.5
30.5
87
232
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
73.8
30.4
34
5
K07.60
ICD-10 Finland
Snapping jaw
5.3
29.2
65
141
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
111.5
29.1
31
*
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
6.4
25.8
45
77
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
30.7
25.8
34
12
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
53.7
25.6
30
6
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
66.3
22.1
25
*
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
3.6
21.1
80
258
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
8.3
20.7
28
36
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
209.7
19.7
20
*
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
46.3
18.4
22
5
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
4.3
18.2
51
132
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
55.1
18.1
21
*
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
7.1
18.1
28
42
EBB10
NOMESCO Finland
Insertion of dental implant
18.0
17.6
27
16
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
8.2
17.6
24
31
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
7.1
16.3
25
37
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
7.3
15.4
23
33
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
15.2
73
270
SXC03
NOMESCO Finland
Other oral or dental procedure
23.3
14.4
20
9
K00.00
ICD-10 Finland
Hypodontia
5.1
14.3
31
65
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
14.3
13.9
23
17
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
3.5
13.5
50
157
K07.4
ICD-10 Finland
Malocclusion, unspecified
5.4
13.3
27
53
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
33.2
12.7
16
5
EB1WA, ,
NOMESCO Finland
17.0
11.8
18
11
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
13.1
11.8
20
16
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
2.9
11.5
58
219
SAA02
NOMESCO Finland
Basic examination of mouth
2.7
11.2
354
2875
OIKK, ,
NOMESCO Finland
2.8
11.2
62
246
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
3.4
11.0
41
129
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.9
10.9
33
90
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
3.7
10.8
36
105
SDA03
NOMESCO Finland
Periodontal treatment
2.0
10.6
181
1156
WZA90
NOMESCO Finland
Other medical or dental certificate
2.0
9.8
140
836
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
15.5
9.6
15
10
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
9.4
119
677
SJB30
NOMESCO Finland
Extraoral traction arrangements and operation instruction, removable appliance
4.1
9.3
26
67
K01.0
ICD-10 Finland
Embedded teeth
4.0
9.1
26
68
WX720
NOMESCO Finland
Own respiration
4.0
9.1
26
68
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
4.4
9.0
23
55
Z3229
NOMESCO Finland
Other healthcare associate professional
2.7
8.9
50
200
SPC20
NOMESCO Finland
Implant borne crown
20.5
8.5
12
6
SPA02
NOMESCO Finland
Preparation for dental prosthetics
4.8
8.4
19
41
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
6.7
8.3
20
31
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.2
8.2
22
55
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.2
8.1
76
383
EBB15
NOMESCO Finland
Insertion of dental implant abutment
13.4
7.9
13
10
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
8.7
7.9
16
19
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
18.8
7.6
11
6
SJE90
NOMESCO Finland
Orthodontic finishing
9.1
7.6
15
17
SPC10
NOMESCO Finland
Standard dental crown
10.3
7.6
14
14
EBA10
NOMESCO Finland
Operative extraction of tooth
2.0
7.5
95
536
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.9
7.5
108
638
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.3
7.5
62
297
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
13.7
7.4
12
9
ZXA10
NOMESCO Finland
Bilateral
2.1
7.4
78
412
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.8
7.4
174
1199
SAA01
NOMESCO Finland
Simple examination of mouth
2.0
7.1
333
2799
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.1
6.8
29
99
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
8.9
6.6
13
15
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
5.5
6.5
18
34
OIKRE, ,
NOMESCO Finland
6.4
6.5
16
26
G50.1
ICD-10 Finland
Atypical facial pain
7.6
6.5
14
19
SPA51
NOMESCO Finland
Determination of bite and dental arch location, demanding
14.6
6.4
10
7
OIKKK, ,
NOMESCO Finland
9.5
6.3
12
13
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
+∞
6.3
6
*
J01CE02
ATC
phenoxymethylpenicillin; oral
1.7
6.2
279
2258
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
29
144
2.09
3.24
2.2
3.0
60.46
99.20
ng/l
1.16
24
131
183
1503
1.39
2.76
3.0
3.3
0.00
0.00
estimate
-0.00
26
295
181
1487
1.39
2.71
4.4
4.6
0.00
0.00
estimate
-0.00
27
305
181
1491
1.38
2.65
3.0
3.3
0.00
0.00
estimate
0.50
27
311
11
38
2.95
2.43
2.0
1.7
13.00
13.27
%
0.42
11
38
71
521
1.44
1.98
2.1
2.0
—
—
—
0
0
330
3063
1.40
1.94
11.7
13.5
13.90
14.00
%
0.16
321
3016
7
22
3.22
1.88
2.7
2.1
—
1224630.00
iu/ml
—
0
5
336
3133
1.40
1.88
9.2
11.8
3.94
3.92
mmol/l
0.55
327
3029
60
432
1.46
1.85
1.7
1.5
435.91
17632043.21
pmol/l
0.50
50
380
335
3128
1.39
1.80
9.2
11.7
139.61
139.67
mmol/l
0.18
329
3035
91
715
1.35
1.70
3.0
3.1
1.02
1.02
kg/l
1.26
12
97
273
2493
1.28
1.60
4.9
4.3
38.07
38.21
mmol/mol
0.10
258
2363
58
429
1.41
1.56
2.1
1.9
—
—
—
0
0
135
1134
1.28
1.56
3.0
3.2
—
—
—
0
0
7
27
2.62
1.52
6.3
5.8
0.68
1.57
ug/l
—
7
27
276
2533
1.27
1.50
4.1
3.8
14.31
14.48
pmol/l
0.69
252
2332
316
2953
1.31
1.47
4.6
4.3
1.82
2.23
mu/l
0.52
290
2765
7
28
2.53
1.46
1.1
1.2
241.86
186.83
pmol/l
—
7
28
7
150
0.46
1.34
1.0
1.2
—
—
—
0
0
186
1652
1.23
1.28
3.2
5.3
6.33
6.41
mmol/l
0.26
169
1491
23
147
1.60
1.26
1.1
1.2
2.41
4.04
u/ml
0.31
14
97
151
1317
1.23
1.23
4.2
8.4
1.23
1.22
mmol/l
2.55
130
1168
315
2968
1.26
1.21
3.8
3.7
—
—
—
0
0
23
150
1.57
1.17
1.8
1.6
—
—
—
0
0
20
127
1.60
1.13
1.2
1.1
3.55
2.18
u/ml
0.16
13
83
292
2737
1.23
1.12
3.6
3.4
5.64
5.69
mmol/l
0.40
275
2527
17
266
0.62
1.10
4.4
5.1
—
—
—
0
0
8
41
1.97
1.09
1.3
1.3
—
—
—
0
0
243
2248
1.20
1.02
3.4
3.9
7.80
8.86
mm/h
1.27
233
2081
0
30
0.00
0.97
0.0
1.4
—
—
—
0
0
20
133
1.53
0.96
1.1
1.2
13.92
8.73
u/ml
0.44
14
94
13
77
1.71
0.96
2.7
11.1
1.56
1.54
%
0.06
13
70
44
340
1.33
0.96
1.4
1.6
1200.92
1147.19
nmol/l
0.17
37
269
6
30
2.01
0.87
1.0
1.1
—
—
—
0
0
13
80
1.65
0.85
1.4
1.3
245.29
322.73
ug/g
—
7
39
23
318
0.71
0.85
6.2
11.1
24.50
24.98
mmol/l
0.57
23
318
8
45
1.79
0.84
1.3
1.1
—
—
—
0
0
256
2704
0.86
0.77
8.0
8.8
95.96
95.07
ml/min/173m2
0.24
197
2070
351
3399
1.23
0.73
7.2
8.7
27.48
26.87
u/l
0.18
341
3294
6
109
0.54
0.73
1.0
1.8
—
—
—
0
0
12
76
1.60
0.72
3.8
2.8
78.16
18.51
mu/l
0.46
12
71
5
26
1.93
0.71
1.0
1.1
—
—
—
0
0
151
1376
1.15
0.70
2.3
2.7
—
—
—
0
0
17
238
0.70
0.69
1.5
1.4
—
—
—
0
0
91
798
1.18
0.68
2.4
2.8
54.95
29.70
ng/l
0.29
41
416
298
2852
1.16
0.68
3.8
3.8
2.74
2.82
mmol/l
0.76
284
2680
20
271
0.72
0.68
1.2
1.2
—
—
—
0
0
5
93
0.53
0.67
1.0
1.1
—
—
—
0
0
5
28
1.80
0.66
1.2
1.2
—
—
—
0
0
11
70
1.59
0.66
2.5
1.5
—
—
—
0
0
344
3334
1.20
0.65
9.3
10.7
22.48
21.02
mg/l
0.36
263
2443
65
556
1.20
0.64
1.7
1.5
—
—
—
0
0
62
528
1.21
0.64
1.3
1.4
19.92
20.11
nmol/l
0.04
55
455
296
2837
1.16
0.64
3.6
3.6
4.58
4.67
mmol/l
0.80
282
2689
83
728
1.18
0.63
2.4
2.3
2.46
2.80
mg/l
0.65
76
631
22
289
0.75
0.62
2.8
8.4
104.73
104.77
mmol/l
0.01
22
289
23
300
0.75
0.62
5.4
6.6
1.55
1.53
mmol/l
0.01
11
210
0
21
0.00
0.60
0.0
3.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
208.54
—
0
21
97
865
1.16
0.60
2.5
2.3
—
—
—
0
0
0
22
0.00
0.59
0.0
11.1
—
—
—
0
0
149
1371
1.14
0.59
4.2
6.7
13.02
11.08
umol/l
0.59
143
1287
7
111
0.62
0.59
1.0
1.1
—
—
—
0
0
7
113
0.61
0.59
1.6
2.5
—
—
—
0
0
7
114
0.61
0.58
1.0
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
1.7
—
—
—
0
0
0
23
0.00
0.58
0.0
1.7
—
—
—
0
0
0
23
0.00
0.58
0.0
1.7
—
—
—
0
0
27
212
1.29
0.57
2.5
2.7
—
—
—
0
0
5
88
0.56
0.56
1.2
2.2
—
—
—
0
0
6
38
1.59
0.54
1.2
1.4
—
—
—
0
0
6
38
1.59
0.54
2.7
3.7
—
—
—
0
0
44
520
0.83
0.54
1.5
1.7
1.34
1.40
%
0.43
38
482
9
133
0.67
0.52
1.4
1.6
0.20
0.23
g/l
—
9
126
9
135
0.66
0.52
1.4
1.6
1.10
1.20
g/l
—
9
126
33
271
1.24
0.50
2.5
2.4
28.04
207.97
u/l
0.51
28
231
292
2817
1.13
0.49
3.5
3.6
1.46
1.45
mmol/l
0.11
278
2656
11
153
0.71
0.46
1.2
1.4
—
—
—
0
0
8
119
0.67
0.46
1.6
1.3
—
—
—
0
0
229
2185
1.11
0.46
4.7
6.5
78.41
85.69
u/l
1.42
221
2063
8
121
0.65
0.46
1.5
5.8
0.86
1.52
%
—
8
121
89
806
1.13
0.45
2.5
2.1
—
—
—
0
0
10
140
0.71
0.44
1.1
1.3
—
—
—
0
0
5
31
1.62
0.43
1.0
1.2
—
—
—
0
0
5
32
1.57
0.42
1.0
1.2
—
—
—
0
0
165
1555
1.10
0.41
3.1
2.9
65.82
80.12
ug/l
1.00
155
1454
0
15
0.00
0.41
0.0
7.8
—
—
—
0
0
108
996
1.11
0.41
6.9
8.1
1.08
1.11
inr
0.33
46
314
0
17
0.00
0.40
0.0
1.0
—
1369.12
—
0
17
0
17
0.00
0.40
0.0
6.7
—
—
—
0
0
0
17
0.00
0.40
0.0
6.8
—
—
—
0
0
0
17
0.00
0.40
0.0
5.3
—
16.22
—
0
17
0
18
0.00
0.40
0.0
6.2
—
—
—
0
0
0
19
0.00
0.39
0.0
3.7
—
66.56
—
0
19
0
19
0.00
0.39
0.0
1.6
—
15.91
—
0
8
81
738
1.12
0.38
1.8
1.7
1.56
1.37
mmol/l
0.81
70
663
8
113
0.70
0.37
1.5
6.1
0.78
0.65
%
—
8
113
16
125
1.29
0.37
2.6
10.8
25.24
24.53
mmol/l
0.46
16
116
112
1041
1.10
0.37
4.4
6.0
37.75
37.49
g/l
0.24
100
992
9
71
1.27
0.36
6.8
1.6
—
—
—
0
0
6
42
1.43
0.35
2.0
1.4
—
—
—
0
0
5
80
0.62
0.35
4.8
10.4
—
388.44
—
0
18
23
276
0.82
0.35
2.1
2.5
0.56
0.68
ug/l
—
8
148
97
902
1.10
0.32
1.6
1.7
102.13
98.83
pmol/l
0.28
53
455
51
457
1.13
0.32
2.7
3.3
69.32
770.63
ng/l
1.99
34
286
16
197
0.80
0.31
1.4
1.8
—
—
—
0
0
22
257
0.85
0.27
3.4
4.7
322.00
248.02
u/l
0.43
22
246
57
521
1.11
0.27
1.2
1.2
13.32
8.42
u/ml
0.17
23
203
5
74
0.67
0.26
1.8
1.3
—
—
—
0
0
67
621
1.09
0.24
3.8
4.0
2.95
12.51
mg/mmol
3.28
42
416
115
1091
1.08
0.24
1.7
1.5
1.15
2.40
u/ml
0.94
23
249
15
180
0.83
0.24
1.3
1.4
—
—
—
0
0
15
180
0.83
0.24
1.3
1.4
—
—
—
0
0
15
180
0.83
0.24
1.3
1.4
—
—
—
0
0
15
180
0.83
0.24
1.3
1.4
—
—
—
0
0
6
81
0.74
0.24
2.7
1.9
—
—
—
0
0
6
84
0.71
0.24
2.7
1.8
—
—
—
0
0
42
462
0.90
0.23
2.0
3.5
404.14
634.23
ng/l
0.70
31
385
5
38
1.32
0.23
2.6
1.6
—
—
—
0
0
12
97
1.24
0.23
1.3
1.6
—
—
—
0
0
83
780
1.08
0.23
2.8
3.5
0.00
0.00
estimate
0.50
26
298
15
178
0.84
0.22
1.3
1.4
181.60
297.95
miu/ml
—
8
87
41
373
1.11
0.22
3.5
3.5
25.72
22.14
%
0.48
12
140
92
971
0.93
0.21
3.0
3.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
2.5
—
30.00
—
0
11
0
11
0.00
0.21
0.0
1.1
—
9.42
—
0
11
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
12.68
—
0
10
0
12
0.00
0.21
0.0
1.0
—
30.14
—
0
7
0
12
0.00
0.21
0.0
2.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
561.14
—
0
7
0
12
0.00
0.21
0.0
1.0
—
64.49
—
0
12
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
31
344
0.89
0.20
1.5
1.5
—
—
—
0
0
276
2706
1.06
0.20
3.1
3.3
1.24
1.25
mmol/l
0.11
259
2544
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
385
3819
1.13
0.20
14.2
15.6
259.05
259.74
e9/l
0.08
377
3709
123
1182
1.06
0.18
2.1
1.8
—
—
—
0
0
34
372
0.91
0.18
2.6
2.5
2.44
2.43
mmol/l
0.25
29
319
12
142
0.84
0.17
1.0
1.7
—
—
—
0
0
7
61
1.15
0.17
1.4
1.2
—
—
—
0
0
385
3822
1.12
0.17
14.1
15.8
40.57
40.60
%
0.03
350
3625
66
623
1.07
0.17
2.0
3.1
326.38
5941.71
umol/l
2.42
61
558
25
277
0.90
0.16
2.4
2.4
21511.41
4499.86
u/l
—
8
105
8
72
1.11
0.16
2.3
1.4
10.53
18.82
u/l
—
8
62
19
168
1.14
0.16
1.2
1.6
—
—
—
0
0
197
1924
1.05
0.15
7.0
9.3
3.73
3.82
e9/l
0.25
175
1654
385
3825
1.11
0.15
14.1
15.6
4.65
4.60
e12/l
1.23
375
3707
51
481
1.07
0.14
3.2
3.1
0.58
0.85
e6/l
0.51
28
274
8
100
0.80
0.13
2.8
4.1
3.70
10.77
umol/l
—
8
75
10
117
0.85
0.13
1.6
1.8
—
—
—
0
0
43
457
0.93
0.13
2.9
9.0
1.15
1.15
mmol/l
0.05
37
430
31
287
1.09
0.13
1.9
1.8
—
—
—
0
0
18
200
0.90
0.12
1.5
1.5
—
—
—
0
0
35
328
1.07
0.11
1.9
3.0
23.46
24.61
%
0.20
28
290
44
464
0.94
0.11
3.6
3.2
3.12
3.16
e6/l
0.02
23
257
11
125
0.88
0.10
2.1
6.0
127.91
167.30
%
1.43
11
125
5
46
1.09
0.09
2.6
1.6
—
—
—
0
0
51
533
0.95
0.09
1.2
1.3
17.15
27.45
iu/ml
0.79
21
155
6
54
1.11
0.09
2.5
1.1
—
—
—
0
0
5
63
0.79
0.08
1.0
1.8
—
—
—
0
0
5
63
0.79
0.08
1.0
1.8
—
—
—
0
0
5
65
0.77
0.08
1.0
2.0
—
—
—
0
0
7
66
1.06
0.08
1.1
1.3
—
—
—
0
0
7
66
1.06
0.08
1.1
1.3
—
—
—
0
0
6
71
0.84
0.07
7.7
4.1
47.17
54.00
%
—
6
71
31
294
1.06
0.07
1.9
1.8
—
—
—
0
0
8
92
0.87
0.07
1.5
2.7
399.25
466.53
mg/l
—
8
87
14
152
0.92
0.06
1.9
1.6
—
—
—
0
0
38
367
1.04
0.04
1.3
1.5
—
—
—
0
0
125
1267
0.98
0.04
2.5
2.8
72.22
71.67
nmol/l
0.08
117
1179
78
794
0.98
0.04
3.3
3.5
0.45
0.30
e6/l
0.21
60
596
30
289
1.04
0.04
1.1
1.1
—
—
—
0
0
20
209
0.95
0.03
1.8
1.9
—
—
—
0
0
87
859
1.02
0.02
2.2
3.0
2.38
2.37
mmol/l
0.69
80
777
16
167
0.96
0.01
1.5
1.6
—
—
—
0
0
122
1213
1.01
0.01
4.0
8.3
1.23
1.22
mmol/l
1.83
111
1133
14
146
0.96
0.00
2.0
2.3
14.06
47.43
u/ml
1.30
14
139
64
634
1.01
0.00
1.5
2.5
0.75
1.07
mg/l
0.80
48
463
10
102
0.98
0.00
1.2
1.5
—
0.02
—
0
16
13
129
1.01
0.00
1.9
1.9
—
—
—
0
0
13
131
0.99
0.00
1.5
1.4
—
—
—
0
0
167
1668
1.00
0.00
4.9
6.6
52.67
54.14
%
1.00
160
1592
170
1698
1.00
0.00
5.3
6.8
33.02
31.31
%
1.41
162
1625
24
241
1.00
0.00
3.1
11.1
1.63
0.75
mmol/l
0.78
18
194
40
399
1.00
0.00
1.8
1.9
—
—
—
0
0
11
113
0.97
0.00
1.3
2.1
38.73
38.62
u/l
0.01
11
107
13
127
1.02
0.00
1.3
1.5
—
—
—
0
0
20
197
1.02
0.00
2.3
11.4
128.50
124.27
g/l
0.51
20
191
29
287
1.01
0.00
1.3
1.3
101.03
146.05
iu/ml
0.36
11
115
12
124
0.97
0.00
1.8
1.3
—
—
—
0
0
5
56
0.89
0.00
3.8
4.3
443.40
373.41
umol/l
—
5
51
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
7
74
0.95
0.00
4.4
2.7
959.37
1853.69
u/ml
—
7
64
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
5
52
0.96
0.00
2.6
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
30.09
—
0
8
5
58
0.86
-0.00
1.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.8
—
—
—
0
0
70
700
1.00
-0.00
1.8
2.4
—
—
—
0
0
8
87
0.92
-0.00
2.8
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.5
—
24.13
—
0
8
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
7
79
0.88
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
7.43
—
0
7
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_MN_PROGN_AND_SURGRT_INCLAVO and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have K11_MN_PROGN_AND_SURGRT_INCLAVO.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: K11_MN_PROGN_AND_SURGRT_INCLAVO – Mandibular prognathia AND surgery (LeFortI or BSSO), including avohilmo
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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