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Melanoma in situ of lower limb, including hip

CD2_INSITU_MELANOMA_LOWERLIMB

melanoma: A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D03.7&
  • Cause of death: ICD-10 D03.7&

2 out of 7 registries used, show all original rules.

239

4. Check minimum number of events

None

239

5. Include endpoints

None

239

6. Filter based on genotype QC (FinnGen only)

232

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D03
Name in latin
Melanoma in situ coxae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 232 175 57
Unadjusted period prevalence (%) 0.05 0.06 0.03
Median age at first event (years) 65.13 63.62 69.79

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
239
Matched controls
2390
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D03.7
ICD-10 Finland
Melanoma in situ of lower limb, including hip
+∞
307.7
239
*
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
112.1
274.9
154
38
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
42.4
100.1
63
20
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
18.6
78.4
70
52
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
11.5
70.8
93
125
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
289.5
65.8
64
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
11.7
57.8
69
80
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
12.5
55.5
62
65
D22
ICD-10 Finland
Melanocytic naevi
11.4
42.5
49
53
R23.8
ICD-10 Finland
Other and unspecified skin changes
5.9
40.4
107
287
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
7.8
34.7
55
88
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
14.1
32.1
31
25
C43.72
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip: 'superficial spreading' type
127.0
31.5
33
*
L57.0
ICD-10 Finland
Actinic keratosis
5.3
27.1
68
168
S18
ICPC
Laceration/cut
4.0
22.5
164
851
TQW99
NOMESCO Finland
Other minor procedure on skin
6.3
21.0
39
72
C43.70
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip without histology
120.6
20.9
22
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
9.0
20.0
26
32
C43.79
ICD-10 Finland
Malignant melanoma of the lower extremity including hip or other unspecified histology
108.7
18.9
20
*
8720/3-C44.7
ICD-O-3
Malignant melanoma, NOS, of skin of lower limb and hip
72.4
18.0
20
*
TQW40, ,
SPAT
5.1
16.8
39
88
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
64.6
16.0
18
*
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
170.7
15.7
16
*
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
41.0
15.6
19
5
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
4.0
13.7
43
123
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
4.3
13.2
37
97
S82
ICPC
Naevus/mole
3.3
12.9
58
211
C43.7
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of lower limb, including hip
73.9
12.7
14
*
D03.5
ICD-10 Finland
Melanoma in situ of trunk
39.8
12.4
15
*
ZZA00
NOMESCO Finland
Split skin graft
10.9
12.3
23
23
C43
ICD-10 Finland
Malignant melanoma of skin
49.3
12.0
14
*
ZZR00
NOMESCO Finland
Flap of skin
12.0
11.8
21
19
S77
ICPC
Malignant neoplasm of skin
21.3
11.3
16
8
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
17.0
10.5
16
10
8720/2-C44.7
ICD-O-3
Melanoma in situ of skin of lower limb and hip
+∞
10.5
10
*
L82
ICD-10 Finland
Seborrhoeic keratosis
2.7
10.0
68
308
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.9
9.7
22
48
D03.6
ICD-10 Finland
Melanoma in situ of upper limb, including shoulder
104.0
9.5
10
*
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
13.2
9.0
15
12
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
20.9
8.6
12
6
C43.71
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip originating in lentigo maligna
+∞
8.4
8
*
C43.73
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip nodular
+∞
8.4
8
*
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
34.6
8.1
10
*
ZXC50
NOMESCO Finland
Cryotherapy
4.9
8.0
18
39
XQ845
NOMESCO Finland
Dermatoscopy
9.9
7.9
15
16
XQ848
NOMESCO Finland
Dermatological photography
6.2
7.4
19
33
TQW11
NOMESCO Finland
Vacuum treatment of wound
9.8
7.4
14
15
D03
ICD-10 Finland
Melanoma in situ
+∞
7.3
7
*
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
8.3
7.2
15
19
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
31.0
7.2
9
*
SPAT1153
SPAT
Removal of sutures
2.1
6.8
94
567
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
9.1
6.6
13
15
QDE99, ,
SPAT
71.7
6.5
7
*
8090/3-C44.7
ICD-O-3
Basal cell carcinoma, NOS, of skin of lower limb and hip
18.6
6.3
9
5
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
5.6
6.3
17
32
C43.60
ICD-10 Finland
Malignant melanoma of the upper extremity including the shoulder without histology
+∞
6.3
6
*
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
8.0
6.2
13
17
Z2221
NOMESCO Finland
Medical doctor
2.1
6.1
81
476
D23.7
ICD-10 Finland
Benign neoplasm: Skin of lower limb, including hip
13.0
6.1
10
8

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
134
253
10.78
78.33
1.9
1.2
—
—
—
0
0
208
878
11.55
50.05
4.2
2.1
—
—
—
0
0
72
198
4.77
25.03
1.5
1.4
—
—
—
0
0
39
92
4.87
15.95
1.8
1.2
—
—
—
0
0
233
2165
4.03
4.19
12.3
10.3
24.53
24.57
u/l
0.02
224
2082
51
298
1.90
3.76
3.6
2.8
1.42
2.53
e6/l
0.86
26
153
9
19
4.88
3.27
1.9
1.5
—
—
—
0
0
224
2061
2.38
2.82
5.0
5.1
2.71
2.76
mmol/l
0.38
205
1886
16
68
2.45
2.62
1.2
1.2
—
—
—
0
0
218
1996
2.05
2.60
4.7
4.6
5.74
5.90
mmol/l
1.62
199
1822
234
2232
3.31
2.53
24.0
20.4
6.55
6.56
e9/l
0.05
229
2165
6
12
5.10
2.41
1.8
1.8
9.53
13.33
umol/l
—
6
12
41
259
1.70
2.32
1.4
1.3
—
—
—
0
0
85
642
1.50
2.28
5.2
4.0
7.40
7.40
ph
0.08
14
109
119
962
1.47
2.28
8.7
6.0
—
—
—
0
0
82
615
1.51
2.27
1.8
2.0
300.63
295.41
u/l
0.01
76
579
218
2018
1.91
2.17
4.3
4.6
4.63
4.74
mmol/l
0.88
202
1858
142
1198
1.46
2.12
9.8
9.2
3.98
3.93
e9/l
0.11
123
1053
127
1055
1.43
2.03
8.7
5.9
0.18
0.18
e9/l
0.02
111
933
35
221
1.68
1.99
1.7
1.6
—
—
—
0
0
71
533
1.47
1.92
4.6
2.8
—
—
—
0
0
12
52
2.38
1.91
1.2
1.2
—
—
—
0
0
114
942
1.40
1.81
6.1
5.5
1.23
1.22
mmol/l
0.39
108
856
90
714
1.42
1.80
4.9
3.6
51.17
65.19
e6/l
0.19
59
493
215
2005
1.72
1.75
4.4
4.5
1.54
1.55
mmol/l
0.13
199
1834
34
221
1.63
1.74
3.4
2.8
0.75
0.73
ug/l
0.08
26
154
60
446
1.46
1.70
3.9
1.7
4.63
1.03
mg/l
0.54
43
362
13
62
2.16
1.69
4.1
1.7
526.00
860.64
ug/l
0.18
13
57
223
2108
1.86
1.63
18.6
15.7
3.95
3.96
mmol/l
0.34
218
2050
77
604
1.41
1.62
4.2
3.0
12.34
158.77
e6/l
0.74
56
453
71
549
1.42
1.62
4.6
2.9
0.33
0.40
e6/l
0.14
51
403
122
1033
1.37
1.62
6.1
6.3
1.24
1.22
mmol/l
1.19
107
891
15
78
1.98
1.58
1.2
1.4
—
—
—
0
0
122
1039
1.36
1.53
8.5
5.6
1.90
1.96
e9/l
0.14
107
932
5
15
3.38
1.53
1.4
1.2
—
—
—
0
0
205
1905
1.54
1.51
5.8
5.7
39.23
39.65
mmol/mol
0.26
186
1769
120
1021
1.35
1.51
8.6
5.5
0.59
0.56
e9/l
0.70
104
891
24
148
1.69
1.51
5.7
7.8
—
—
—
0
0
222
2103
1.78
1.50
18.0
15.6
139.96
139.78
mmol/l
0.58
217
2049
178
1613
1.41
1.49
8.7
7.1
74.50
76.04
u/l
0.35
171
1496
120
1025
1.34
1.46
8.6
5.5
0.04
0.04
e9/l
0.79
104
893
41
292
1.49
1.43
1.7
1.8
—
—
—
0
0
7
29
2.46
1.40
1.7
1.2
—
—
—
0
0
20
120
1.73
1.39
1.3
1.2
—
—
—
0
0
105
884
1.33
1.39
4.2
4.2
36.23
35.80
g/l
0.37
98
817
215
2030
1.59
1.34
16.1
13.5
24.18
21.83
mg/l
0.35
166
1581
225
2150
1.79
1.31
18.8
16.1
77.07
74.91
umol/l
0.49
225
2150
144
1279
1.32
1.27
3.2
3.0
37.00
45.89
u/l
1.31
131
1193
105
898
1.30
1.20
11.7
9.5
0.01
0.00
e9/l
0.11
82
739
35
251
1.46
1.19
1.7
1.3
—
—
—
0
0
5
20
2.53
1.15
1.2
1.4
—
—
—
0
0
18
112
1.66
1.12
4.8
5.6
24.63
25.03
mmol/l
0.20
18
112
33
445
0.70
1.10
4.8
3.8
1.02
1.01
kg/l
—
6
62
65
527
1.32
1.08
8.6
6.9
—
—
—
0
0
65
527
1.32
1.08
2.6
2.7
5828.27
10074.44
umol/l
0.31
56
455
6
124
0.47
1.08
2.5
4.7
—
—
—
0
0
24
163
1.53
1.06
4.6
6.3
1.17
1.32
mmol/l
0.44
24
158
154
1400
1.28
1.04
5.3
4.1
—
—
—
0
0
5
22
2.30
1.04
1.2
1.0
—
—
—
0
0
60
484
1.32
1.03
1.5
1.3
—
—
—
0
0
204
1928
1.40
1.03
3.9
4.0
1.28
1.26
mmol/l
0.25
186
1756
25
173
1.50
1.02
1.6
1.5
—
—
—
0
0
112
983
1.26
1.00
9.5
5.7
27.09
28.15
%
0.52
106
916
11
61
1.84
1.00
2.8
3.3
—
—
—
0
0
76
639
1.28
0.96
2.5
2.1
—
—
—
0
0
42
326
1.35
0.94
2.8
3.0
0.82
0.81
mmol/l
0.32
42
306
12
71
1.73
0.90
2.5
2.9
—
—
—
0
0
8
42
1.94
0.89
1.5
2.1
—
—
—
0
0
33
251
1.37
0.84
2.2
2.1
80.76
133.72
ug/g
1.04
21
197
16
105
1.56
0.84
2.5
2.5
—
—
—
0
0
51
415
1.29
0.83
3.3
2.5
2.81
4.99
e6/l
2.58
46
368
6
32
1.90
0.82
1.2
1.1
—
—
—
0
0
15
98
1.57
0.80
4.7
8.6
—
—
—
0
0
70
595
1.25
0.80
3.9
3.1
27.52
160.37
mg/l
0.60
42
357
0
24
0.00
0.79
0.0
2.7
—
—
—
0
0
68
786
0.81
0.73
2.8
3.7
27.96
33.80
ng/l
0.16
45
567
7
39
1.82
0.73
4.3
2.5
—
—
—
0
0
5
25
2.02
0.73
1.2
1.0
—
—
—
0
0
30
383
0.75
0.72
1.2
1.3
9.27
14.37
u/ml
0.31
12
151
7
40
1.77
0.72
3.1
2.3
—
—
—
0
0
5
26
1.94
0.71
1.4
1.3
—
—
—
0
0
61
518
1.24
0.70
1.6
1.6
25.14
22.25
nmol/l
0.73
52
438
22
162
1.39
0.69
2.1
3.0
68.39
67.31
e9/l
—
9
128
48
398
1.26
0.68
3.0
2.8
581.05
528.83
mosm/kgh2o
0.78
39
333
7
43
1.65
0.67
3.9
2.7
8.09
8.66
kpa
—
7
43
7
43
1.65
0.67
3.9
2.7
5.24
4.96
kpa
—
7
43
7
43
1.65
0.67
3.9
2.7
0.03
2.53
mmol/l
—
7
23
71
616
1.22
0.67
3.8
3.0
6.89
6.89
mmol/l
0.00
59
507
166
1560
1.21
0.66
4.7
4.2
10.44
12.50
mm/h
1.57
151
1417
84
745
1.20
0.63
4.1
3.2
2.34
2.36
mmol/l
0.44
75
654
45
374
1.25
0.63
6.3
5.1
2.72
3.00
ug/l
0.12
39
331
21
157
1.37
0.61
2.1
2.7
—
—
—
0
0
21
157
1.37
0.61
3.9
3.0
18.48
39.52
u/ml
1.35
21
150
25
194
1.32
0.59
2.0
1.5
—
—
—
0
0
94
848
1.18
0.58
2.1
2.0
93.63
97.03
pmol/l
0.26
43
419
46
388
1.23
0.57
3.5
3.4
55.80
194.73
ng/l
0.83
35
296
6
36
1.68
0.57
2.7
3.1
4.64
5.11
e9/l
—
6
36
6
37
1.64
0.56
2.7
3.6
62.50
60.16
%
—
6
37
200
1928
1.23
0.53
5.4
4.9
1.91
1.90
mu/l
0.03
189
1755
6
40
1.51
0.52
5.0
2.2
—
—
—
0
0
16
118
1.38
0.51
1.5
1.5
—
—
—
0
0
78
699
1.17
0.51
2.7
3.0
—
—
—
0
0
164
1713
0.86
0.45
23.1
17.7
330.28
331.28
g/l
0.71
164
1708
5
31
1.63
0.43
1.0
1.1
—
—
—
0
0
5
31
1.63
0.43
1.0
1.1
—
—
—
0
0
5
32
1.57
0.42
4.2
1.8
55.80
58.39
%
—
5
32
5
32
1.57
0.42
1.6
1.5
51.16
43.30
u/l
—
5
26
10
70
1.45
0.42
1.4
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
2.9
—
19.32
—
0
11
0
16
0.00
0.41
0.0
1.0
—
289.91
—
0
11
0
17
0.00
0.41
0.0
1.1
—
17.49
—
0
17
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
68
614
1.15
0.40
3.3
3.9
—
—
—
0
0
27
224
1.23
0.40
1.6
2.5
4.59
6.62
umol/l
1.62
20
194
66
595
1.15
0.40
1.6
1.6
1.36
1.34
mmol/l
0.08
57
502
16
124
1.31
0.40
1.3
1.3
268.79
160.64
u/ml
0.22
16
111
215
2102
1.23
0.38
13.4
12.8
—
—
—
0
0
16
201
0.78
0.37
4.8
7.4
95.24
95.89
%
0.16
16
193
9
71
1.28
0.36
1.9
1.5
—
—
—
0
0
24
200
1.22
0.35
3.9
4.0
—
—
—
0
0
69
631
1.13
0.34
4.8
3.7
5.94
8.13
mg/mmol
0.29
41
358
20
164
1.24
0.34
3.3
3.8
—
—
—
0
0
6
46
1.31
0.33
2.0
1.2
—
—
—
0
0
169
1631
1.12
0.32
4.3
4.1
14.91
14.79
pmol/l
0.27
158
1473
19
156
1.24
0.32
1.5
1.4
—
—
—
0
0
7
52
1.36
0.31
4.3
2.7
7.40
7.42
ph
—
7
45
7
53
1.33
0.31
4.3
3.1
37.14
29.73
u/ml
—
7
53
24
279
0.84
0.29
1.4
1.3
544.00
502.42
titre
—
5
66
61
662
0.89
0.28
3.8
2.9
—
—
—
0
0
52
568
0.89
0.27
2.4
3.3
—
—
—
0
0
35
392
0.87
0.27
1.4
1.3
41.92
39.18
iu/ml
—
9
132
51
555
0.90
0.25
3.7
3.7
0.00
0.00
estimate
-0.00
16
184
11
137
0.79
0.25
1.5
1.3
—
—
—
0
0
10
78
1.29
0.24
2.2
4.3
—
—
—
0
0
25
218
1.16
0.24
3.5
7.2
5.16
5.15
kpa
0.01
25
210
25
218
1.16
0.24
3.5
7.2
12.50
11.90
kpa
0.21
25
210
29
258
1.14
0.22
2.4
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
7.99
—
0
12
0
12
0.00
0.21
0.0
1.1
—
28.33
—
0
12
21
183
1.16
0.21
2.7
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
7.50
—
0
13
0
13
0.00
0.21
0.0
6.6
—
—
—
0
0
10
80
1.26
0.21
3.0
2.0
6.22
13.68
nmol/l
—
10
71
0
14
0.00
0.20
0.0
1.6
—
72.57
—
0
14
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
57
532
1.09
0.20
4.7
3.8
—
—
—
0
0
14
165
0.84
0.20
3.8
3.2
—
—
—
0
0
36
328
1.11
0.20
3.5
2.2
13.15
13.53
umol/l
0.12
30
302
24
215
1.13
0.17
2.3
1.4
—
—
—
0
0
141
1447
0.94
0.16
4.0
3.8
—
—
—
0
0
12
140
0.85
0.15
2.5
2.6
—
—
—
0
0
13
112
1.17
0.14
1.5
1.3
—
—
—
0
0
8
100
0.79
0.14
2.4
1.5
—
—
—
0
0
42
395
1.08
0.13
1.7
1.7
1162.22
1213.77
nmol/l
0.10
23
294
49
464
1.07
0.13
4.5
3.5
—
—
—
0
0
105
1019
1.05
0.12
5.0
4.9
0.00
0.00
estimate
-0.00
17
184
32
299
1.08
0.11
3.7
2.2
2.12
2.36
g/l
1.88
27
270
5
46
1.09
0.09
1.2
1.1
—
—
—
0
0
13
116
1.13
0.09
4.6
8.7
93.85
94.58
%
0.14
13
116
14
155
0.90
0.09
1.3
1.3
—
—
—
0
0
26
243
1.08
0.09
4.3
6.3
103.96
104.00
mmol/l
0.02
26
243
103
1006
1.04
0.09
3.5
3.6
0.00
0.00
estimate
-0.00
19
199
6
54
1.11
0.09
1.2
1.1
—
—
—
0
0
43
412
1.05
0.08
1.3
1.4
2.20
2.35
g/l
0.25
17
238
30
284
1.06
0.07
1.3
1.2
—
—
—
0
0
105
1030
1.03
0.07
3.5
3.6
0.00
0.00
estimate
-0.00
18
180
9
101
0.89
0.06
1.6
3.7
—
—
—
0
0
119
1171
1.03
0.06
4.5
4.3
6.50
6.60
mmol/l
0.20
109
1097
48
496
0.96
0.06
2.5
2.0
2.40
3.24
mg/l
2.64
41
430
92
903
1.03
0.05
3.0
2.6
125.83
109.00
ug/l
0.44
85
828
15
161
0.93
0.05
1.3
1.4
—
—
—
0
0
93
941
0.98
0.02
20.8
12.8
1.23
1.24
inr
0.04
27
269
14
134
1.05
0.00
1.1
1.2
82.20
154.56
iu/ml
—
6
64
10
99
1.01
0.00
1.9
1.7
—
—
—
0
0
10
103
0.97
0.00
2.7
2.5
0.67
0.66
%
—
10
103
15
147
1.02
0.00
1.1
1.2
—
—
—
0
0
46
455
1.01
0.00
1.2
1.2
2.37
1.42
u/ml
—
9
132
11
106
1.04
0.00
2.7
2.5
1.24
1.13
%
0.16
11
106
43
432
0.99
0.00
1.5
1.8
508.66
468.97
pmol/l
0.34
35
363
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
185.24
—
0
8
0
8
0.00
0.00
0.0
4.0
—
47.87
—
0
8
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
32.00
—
0
9
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
9.1
—
—
—
0
0
18
180
1.00
-0.00
4.6
3.6
2.03
1.87
mmol/l
0.11
18
148
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
52
0.96
-0.00
1.6
6.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.3
—
2.32
—
0
9
7
76
0.92
-0.00
2.1
4.9
37.59
28.39
mg/l
—
7
61
7
78
0.89
-0.00
1.0
1.1
—
—
—
0
0
7
76
0.92
-0.00
2.1
4.9
72.24
139.77
mg/l
—
7
61
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_MELANOMA_LOWERLIMB – Melanoma in situ of lower limb, including hip

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).