This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Melanoma in situ of lower limb, including hip
CD2_INSITU_MELANOMA_LOWERLIMB
melanoma: A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
200 |
4. Check minimum number of eventsNone |
200 |
5. Include endpointsNone |
200 |
6. Filter based on genotype QC (FinnGen only) |
200 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D03
- Name in latin
- Melanoma in situ coxae
Similar endpoints
↥List of similar endpoints to
Melanoma in situ of lower limb, including hip
based on the number of shared cases.
Similar with more cases:
- Melanoma in situ of lower limb, including hip
- Melanoma in situ
- Melanoma in situ
- Malignant melanoma
- Malignant melanoma, excluding all cancers (controls excluding all cancers)
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 200 | 152 | 48 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.02 |
| Median age at first event (years) | 64.05 | 62.01 | 70.52 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 173
- Matched controls
- 1728
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D03.7
ICD-10 Finland
Melanoma in situ of lower limb, including hip
+∞
250.2
173
*
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
186.1
118.7
115
18
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
141.9
41.9
43
*
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
59.1
35.6
41
9
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
11.0
32.7
69
98
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
23.6
31.9
46
26
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
13.7
26.8
48
47
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
10.5
24.3
50
64
C43.72
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip: 'superficial spreading' type
+∞
21.3
20
*
R23.8
ICD-10 Finland
Other and unspecified skin changes
5.6
18.3
61
153
C43.70
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip without histology
187.2
16.8
17
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
8.8
16.3
36
50
C43.79
ICD-10 Finland
Malignant melanoma of the lower extremity including hip or other unspecified histology
+∞
15.9
15
*
D22
ICD-10 Finland
Melanocytic naevi
11.3
14.9
28
29
8720/3-C44.7
ICD-O-3
Malignant melanoma, NOS, of skin of lower limb and hip
81.3
13.8
15
*
S18
ICPC
Laceration/cut
3.4
13.3
105
538
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
12.4
13.0
23
21
L57.0
ICD-10 Finland
Actinic keratosis
5.3
12.6
41
96
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
12.4
12.4
22
20
C43.7
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of lower limb, including hip
+∞
11.6
11
*
ZZA00
NOMESCO Finland
Split skin graft
11.2
11.4
21
21
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
27.1
11.3
15
6
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
30.2
10.9
14
5
D03.5
ICD-10 Finland
Melanoma in situ of trunk
64.0
10.8
12
*
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
116.7
10.5
11
*
S77
ICPC
Malignant neoplasm of skin
19.9
9.1
13
7
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
4.7
9.1
31
76
C43.73
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip nodular
+∞
8.4
8
*
8720/2-C44.7
ICD-O-3
Melanoma in situ of skin of lower limb and hip
+∞
8.4
8
*
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
35.1
8.2
10
*
TQW99
NOMESCO Finland
Other minor procedure on skin
5.4
7.8
23
48
L82
ICD-10 Finland
Seborrhoeic keratosis
3.1
7.6
45
175
C43
ICD-10 Finland
Malignant melanoma of skin
83.5
7.5
8
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
5.0
7.4
23
51
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
31.4
7.2
9
*
ZZR00
NOMESCO Finland
Flap of skin
9.4
7.2
14
16
S82
ICPC
Naevus/mole
3.4
7.0
35
121
8090/3-C44.7
ICD-O-3
Basal cell carcinoma, NOS, of skin of lower limb and hip
41.7
6.8
8
*
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
9.3
6.7
13
15
8742/2-C44.9
ICD-O-3
Lentigo maligna of skin, NOS
72.4
6.5
7
*
D03.6
ICD-10 Finland
Melanoma in situ of upper limb, including shoulder
72.4
6.5
7
*
C43.71
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip originating in lentigo maligna
+∞
6.3
6
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
5.4
6.1
17
34
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
183
1608
2.62
3.76
17.3
13.2
77.9
78.2
ml/min/173m2
0.05
152
1317
11
30
3.82
3.69
1.5
1.3
—
—
—
0
0
11
30
3.82
3.69
1.5
1.3
—
—
—
0
0
194
1797
3.65
3.46
12.5
10.4
24.5
24.5
u/l
0.02
188
1725
13
44
3.09
3.20
1.3
1.3
—
—
—
0
0
43
258
1.85
2.96
2.3
2.9
1.5
2.8
e6/l
0.88
20
138
45
281
1.78
2.72
2.6
2.7
0.4
1.0
e6/l
1.70
22
157
123
999
1.60
2.63
9.8
9.2
3.9
4.0
e9/l
0.03
109
874
72
521
1.60
2.48
1.9
2.0
327.3
328.0
u/l
0.00
66
488
11
41
2.78
2.32
1.3
1.6
—
—
—
0
0
8
24
3.43
2.20
1.1
1.4
—
—
—
0
0
183
1680
2.05
2.17
4.1
4.6
4.6
4.7
mmol/l
0.87
171
1539
17
82
2.17
2.14
3.4
9.0
23.7
24.9
mmol/l
1.40
17
76
186
1719
2.17
2.13
4.8
5.2
2.7
2.7
mmol/l
0.56
172
1563
181
1668
1.90
1.92
4.6
4.7
5.7
5.9
mmol/l
3.36
167
1518
92
737
1.46
1.87
2.3
2.3
85.6
78.7
nmol/l
1.62
86
642
29
182
1.69
1.72
3.7
3.0
0.8
0.7
ug/l
0.11
21
129
11
49
2.32
1.67
1.4
1.1
—
—
—
0
0
180
1671
1.77
1.64
4.1
4.5
1.6
1.5
mmol/l
0.10
168
1518
12
56
2.22
1.64
1.2
1.2
—
—
—
0
0
18
104
1.80
1.42
1.4
1.7
—
—
—
0
0
188
1781
1.93
1.40
18.9
16.5
76.2
75.4
umol/l
0.14
188
1781
163
1495
1.49
1.37
20.0
15.2
40.3
39.5
%
1.31
118
1061
28
187
1.58
1.33
1.6
1.8
—
—
—
0
0
171
1589
1.53
1.29
5.5
5.9
38.5
39.9
mmol/mol
1.65
157
1469
179
1682
1.61
1.25
16.9
14.0
23.6
21.4
mg/l
0.33
139
1313
59
464
1.39
1.25
3.5
3.0
0.4
0.5
e6/l
0.12
41
343
11
56
2.02
1.24
1.1
1.2
—
—
—
0
0
37
269
1.46
1.20
1.6
1.9
—
—
—
0
0
11
57
1.98
1.19
4.4
1.4
592.2
927.9
ug/l
0.16
11
52
54
674
0.73
1.18
3.7
3.7
—
—
—
0
0
5
20
2.54
1.16
1.8
1.2
—
—
—
0
0
102
881
1.32
1.15
4.8
6.6
1.2
1.2
mmol/l
1.01
90
758
95
813
1.32
1.14
4.8
5.6
1.2
1.2
mmol/l
0.48
89
732
5
21
2.42
1.09
1.0
1.6
—
—
—
0
0
49
383
1.37
1.07
4.1
1.8
5.6
1.0
mg/l
0.55
35
313
27
189
1.50
1.06
1.6
1.9
—
—
—
0
0
9
46
2.00
1.05
1.6
1.4
—
—
—
0
0
50
395
1.35
1.02
2.2
2.1
—
—
—
0
0
54
432
1.34
1.02
1.6
1.6
25.6
22.2
nmol/l
0.82
47
361
147
1351
1.33
1.00
9.1
7.1
74.6
76.5
u/l
0.42
141
1248
19
125
1.57
0.98
1.7
1.7
—
—
—
0
0
7
37
1.92
0.95
1.0
1.4
—
—
—
0
0
36
275
1.38
0.91
2.5
2.9
0.8
0.8
mmol/l
0.32
36
256
30
222
1.41
0.90
4.0
4.6
33.0
32.8
%
0.03
22
132
20
282
0.68
0.87
2.1
1.4
—
—
—
0
0
15
96
1.61
0.87
4.7
5.4
24.5
25.0
mmol/l
0.24
15
96
110
988
1.25
0.82
2.7
2.8
—
—
—
0
0
71
610
1.25
0.77
3.3
3.0
—
—
—
0
0
118
1075
1.24
0.75
3.3
3.0
38.3
44.9
u/l
0.70
107
1002
9
56
1.64
0.73
1.3
1.4
—
—
—
0
0
15
101
1.52
0.72
1.3
1.3
282.8
165.7
u/ml
0.22
15
91
13
85
1.57
0.71
1.2
1.3
—
—
—
0
0
5
28
1.81
0.66
1.0
1.0
—
—
—
0
0
169
1613
1.31
0.66
3.8
4.0
1.3
1.3
mmol/l
0.22
155
1461
22
164
1.38
0.66
3.7
3.4
—
—
—
0
0
31
245
1.31
0.65
4.6
4.5
20.7
20.8
%
0.01
19
126
13
88
1.51
0.62
1.1
1.0
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
25
317
0.76
0.60
1.3
1.3
10.9
16.8
u/ml
—
10
119
58
665
0.82
0.60
2.8
3.7
30.7
37.0
ng/l
0.14
37
470
18
132
1.40
0.59
4.2
2.9
19.7
40.7
u/ml
1.07
18
127
0
23
0.00
0.58
0.0
1.2
—
7.6
—
0
13
139
1306
1.21
0.58
4.8
4.2
9.6
12.7
mm/h
3.13
127
1182
79
707
1.19
0.56
2.1
2.0
95.4
97.3
pmol/l
0.11
34
341
52
447
1.22
0.56
2.4
2.8
353.7
9417.9
umol/l
2.97
46
377
24
188
1.31
0.54
1.4
2.6
4.7
6.8
umol/l
1.41
18
166
6
39
1.55
0.53
1.2
1.5
—
—
—
0
0
19
145
1.34
0.51
4.6
5.9
1.2
1.3
mmol/l
0.32
19
139
167
1606
1.24
0.50
5.3
4.9
1.9
1.9
mu/l
0.05
159
1456
33
274
1.24
0.49
2.9
2.4
12.9
13.6
umol/l
0.25
27
249
26
211
1.27
0.46
4.8
7.0
—
—
—
0
0
7
49
1.44
0.46
1.1
1.1
—
—
—
0
0
143
1360
1.18
0.46
4.3
4.0
15.0
14.8
pmol/l
0.49
135
1223
5
31
1.63
0.43
1.6
1.5
51.2
42.1
u/l
—
5
25
15
114
1.34
0.42
2.2
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
3.6
—
—
—
0
0
0
15
0.00
0.41
0.0
3.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
2.7
—
13.6
—
0
17
37
318
1.20
0.40
6.6
5.1
2.9
3.2
ug/l
0.08
32
280
39
339
1.19
0.38
3.2
3.3
65.2
216.7
ng/l
0.79
29
263
6
42
1.44
0.36
4.7
3.0
40.8
32.1
u/ml
—
6
42
84
779
1.14
0.35
3.5
3.9
—
—
—
0
0
6
43
1.41
0.35
3.7
1.2
—
—
—
0
0
28
327
0.83
0.35
1.4
1.3
45.4
41.9
iu/ml
—
8
107
68
625
1.13
0.33
4.3
3.1
2.3
2.4
mmol/l
0.30
60
539
62
568
1.13
0.31
2.6
2.9
26.8
30.8
u/l
0.94
55
541
29
251
1.18
0.30
3.0
2.3
2.1
2.4
g/l
1.64
24
228
8
67
1.20
0.26
1.5
1.9
—
—
—
0
0
54
497
1.12
0.25
1.5
1.7
1.5
1.4
mmol/l
0.39
47
420
7
92
0.75
0.23
2.7
2.5
1.6
1.1
%
—
7
92
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
79
751
1.09
0.19
2.8
2.6
130.6
109.0
ug/l
0.50
73
687
103
993
1.08
0.17
4.0
4.4
6.4
6.6
mmol/l
0.60
93
928
7
62
1.13
0.17
1.7
2.2
—
—
—
0
0
22
196
1.14
0.17
3.4
7.1
11.7
11.8
kpa
0.05
22
189
22
196
1.14
0.17
3.4
7.1
5.1
5.2
kpa
0.15
22
189
7
63
1.12
0.17
2.4
1.5
—
—
—
0
0
43
460
0.92
0.16
3.9
3.8
0.0
0.0
estimate
0.00
13
146
9
78
1.16
0.15
1.0
1.3
27.4
31.6
iu/l
—
9
68
12
102
1.19
0.15
4.3
8.4
93.7
94.5
%
0.15
12
102
5
47
1.07
0.09
1.8
1.2
—
—
—
0
0
5
48
1.04
0.09
1.4
2.2
24.4
25.8
mmol/l
—
5
38
7
66
1.06
0.08
3.4
2.0
5.4
12.4
nmol/l
—
7
58
43
416
1.04
0.05
2.7
2.0
2.4
3.3
mg/l
2.49
37
362
88
865
1.03
0.05
4.7
5.0
0.0
0.0
estimate
0.00
14
145
12
113
1.07
0.02
1.0
1.2
82.2
175.4
iu/ml
—
6
53
38
387
0.98
0.01
1.2
1.2
2.4
1.6
u/ml
—
9
113
85
857
0.99
0.01
3.4
3.6
0.0
0.0
estimate
0.00
15
150
33
336
0.98
0.00
1.3
1.4
—
—
—
0
0
88
874
1.01
0.00
3.3
3.6
0.0
0.0
estimate
0.00
15
142
10
101
0.99
0.00
1.1
1.3
—
—
—
0
0
22
216
1.02
0.00
4.1
6.1
104.3
103.9
mmol/l
0.19
22
209
52
519
1.00
0.00
4.2
3.0
1119.4
1184.6
ng/l
0.08
44
438
34
343
0.99
0.00
1.8
1.7
1238.2
1192.6
nmol/l
0.07
19
253
37
373
0.99
0.00
1.6
1.8
526.3
455.8
pmol/l
0.67
32
313
12
115
1.05
0.00
1.7
1.6
—
—
—
0
0
11
105
1.05
0.00
1.5
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
2.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.1
—
70.1
—
0
7
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
0.00
1.5
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
8
82
0.97
0.00
1.4
2.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_MELANOMA_LOWERLIMB – Melanoma in situ of lower limb, including hip
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).