This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Melanoma in situ of lower limb, including hip
CD2_INSITU_MELANOMA_LOWERLIMB
melanoma: A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
200 |
4. Check minimum number of eventsNone |
200 |
5. Include endpointsNone |
200 |
6. Filter based on genotype QC (FinnGen only) |
200 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D03
- Name in latin
- Melanoma in situ coxae
Similar endpoints
↥List of similar endpoints to
Melanoma in situ of lower limb, including hip
based on the number of shared cases.
Similar with more cases:
- Melanoma in situ of lower limb, including hip
- Melanoma in situ
- Melanoma in situ
- Malignant melanoma
- Malignant melanoma, excluding all cancers (controls excluding all cancers)
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 200 | 152 | 48 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.02 |
| Median age at first event (years) | 64.05 | 62.01 | 70.52 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 173
- Matched controls
- 1728
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D03.7
ICD-10 Finland
Melanoma in situ of lower limb, including hip
+∞
250.2
173
*
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
186.1
118.7
115
18
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
141.9
41.9
43
*
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
59.1
35.6
41
9
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
11.0
32.7
69
98
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
23.6
31.9
46
26
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
13.7
26.8
48
47
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
10.5
24.3
50
64
C43.72
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip: 'superficial spreading' type
+∞
21.3
20
*
R23.8
ICD-10 Finland
Other and unspecified skin changes
5.6
18.3
61
153
C43.70
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip without histology
187.2
16.8
17
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
8.8
16.3
36
50
C43.79
ICD-10 Finland
Malignant melanoma of the lower extremity including hip or other unspecified histology
+∞
15.9
15
*
D22
ICD-10 Finland
Melanocytic naevi
11.3
14.9
28
29
8720/3-C44.7
ICD-O-3
Malignant melanoma, NOS, of skin of lower limb and hip
81.3
13.8
15
*
S18
ICPC
Laceration/cut
3.4
13.3
105
538
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
12.4
13.0
23
21
L57.0
ICD-10 Finland
Actinic keratosis
5.3
12.6
41
96
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
12.4
12.4
22
20
C43.7
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of lower limb, including hip
+∞
11.6
11
*
ZZA00
NOMESCO Finland
Split skin graft
11.2
11.4
21
21
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
27.1
11.3
15
6
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
30.2
10.9
14
5
D03.5
ICD-10 Finland
Melanoma in situ of trunk
64.0
10.8
12
*
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
116.7
10.5
11
*
S77
ICPC
Malignant neoplasm of skin
19.9
9.1
13
7
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
4.7
9.1
31
76
8720/2-C44.7
ICD-O-3
Melanoma in situ of skin of lower limb and hip
+∞
8.4
8
*
C43.73
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip nodular
+∞
8.4
8
*
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
35.1
8.2
10
*
TQW99
NOMESCO Finland
Other minor procedure on skin
5.4
7.8
23
48
L82
ICD-10 Finland
Seborrhoeic keratosis
3.1
7.6
45
175
C43
ICD-10 Finland
Malignant melanoma of skin
83.5
7.5
8
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
5.0
7.4
23
51
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
31.4
7.2
9
*
ZZR00
NOMESCO Finland
Flap of skin
9.4
7.2
14
16
S82
ICPC
Naevus/mole
3.4
7.0
35
121
8090/3-C44.7
ICD-O-3
Basal cell carcinoma, NOS, of skin of lower limb and hip
41.7
6.8
8
*
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
9.3
6.7
13
15
8742/2-C44.9
ICD-O-3
Lentigo maligna of skin, NOS
72.4
6.5
7
*
D03.6
ICD-10 Finland
Melanoma in situ of upper limb, including shoulder
72.4
6.5
7
*
C43.71
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip originating in lentigo maligna
+∞
6.3
6
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
5.4
6.1
17
34
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_MELANOMA_LOWERLIMB – Melanoma in situ of lower limb, including hip
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).