Traumatic subcutaneous emphysema

ST19_TRAUMAT_SUBCU_EMPHY

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — T79.7 Cause of death: ICD-10 — T79.7 2 out of 7 registries used, show all original rules.	42
4. Check minimum number of events None	42
5. Include endpoints None	42
6. Filter based on genotype QC (FinnGen only)	42

Control definitions (FinnGen only)

Control exclude: ST19_ALIQU_COMPLICATI_PRAECO_TRAUMAT

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: T79
Name in latin: Emphysema traumaticum subcutaneum

NAME	ST19_TRAUMAT_SUBCU_EMPHY
CONTROL_EXCLUDE	ST19_ALIQU_COMPLICATI_PRAECO_TRAUMAT
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	T797
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	T797
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Traumatic subcutaneous emphysema based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	42	16	26
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	62.14	62.97	61.63

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

3.57

2.83

1.5

1.6

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

3.47

2.72

1.5

1.7

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

4.11

2.67

7.3

5.2

1.3

1.2

mmol/l

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

3.10

2.58

1.6

—

(3023368) Bacteria identified in Blood by Culture

2.71

2.42

3.7

4.1

—

(3032080) INR in Blood by Coagulation assay

143

2.58

2.29

5.5

8.1

1.1

1.2

inr

—

(3042936) Bacteria identified in Isolate by Culture

3.03

2.22

2.0

2.3

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

5.50

2.13

1.6

1.8

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

4.21

1.77

2.4

2.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

2.38

1.69

5.1

7.1

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

3.63

1.57

2.0

1.4

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

2.45

1.45

6.3

9.5

1.0

1.1

mmol/l

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

103

2.09

1.41

10.0

4.0

2.4

2.3

mmol/l

0.92

(3016502) Oxygen saturation in Arterial blood

2.58

1.36

7.3

5.5

94.6

96.1

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

114

2.01

1.31

4.4

2.9

37.2

32.6

u/l

0.13

107

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

141

1.98

1.30

2.7

4.4

19.8

42.1

ng/l

0.98

104

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

2.36

1.27

9.1

5.2

5.5

4.8

kpa

—

(3027801) Oxygen [Partial pressure] in Arterial blood

2.36

1.27

9.1

5.2

12.0

11.9

kpa

—

(3044640) Blood type and Crossmatch panel - Blood

101

1.94

1.15

1.8

2.3

—

(3002173) Hemoglobin [Mass/volume] in Arterial blood

2.27

1.09

7.9

5.5

107.9

120.9

g/l

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.13

1.02

4.3

3.9

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

0.00

1.02

0.0

2.3

—

50.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.99

0.93

1.3

1.6

—

(3000991) Gas panel - Venous blood

2.16

0.91

8.3

7.1

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

204

1.72

0.86

5.0

4.3

7.0

6.5

mmol/l

0.90

195

(4010399)

0.00

0.82

0.0

1.4

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

103

1.71

0.79

2.9

3.3

596.2

1067.3

ng/l

0.59

(3022621) pH of Urine by Test strip

2.22

0.77

3.2

1.9

—

(3019060) Gas panel - Arterial blood

2.04

0.73

2.4

4.2

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

1.80

0.73

1.6

1.4

29.6

30.4

iu/ml

—

(3002385) Erythrocyte distribution width [Ratio]

273

1.72

0.70

29.6

18.4

14.4

13.9

0.61

268

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.66

0.64

1.6

1.9

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

292

0.64

0.61

5.9

5.1

2.0

1.9

mu/l

0.31

274

(3000494) Fungus identified in Specimen by Culture

1.83

0.61

1.2

1.5

—

(40768804) Tissue Pathology biopsy report

116

0.62

0.56

2.3

1.8

—

(3022145) Colonoscopy Study observation

1.63

0.55

1.2

—

(40758558) Short blood count panel - Blood

1.58

0.54

4.1

7.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.58

0.54

3.3

1.7

—

(3003694) ABO and Rh group [Type] in Blood

1.53

0.49

1.2

1.5

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

1.48

0.48

5.4

3.0

2.4

2.5

mmol/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

106

1.48

0.47

6.0

3.3

—

(3000492) Spirometry study

1.69

0.45

1.4

1.5

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

155

1.41

0.43

4.1

—

(3017446) Testosterone [Moles/volume] in Serum or Plasma

1.58

0.43

1.2

2.5

12.5

14.7

nmol/l

—

(3020891) Body temperature

0.00

0.42

0.0

4.7

—

(3003327) Ova and parasites identified in Stool by Light microscopy

0.00

0.42

0.0

1.2

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

0.00

0.42

0.0

1.7

—

24.4

—

(3012544) pH of Venous blood

1.49

0.41

3.6

5.9

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

1.4

—

39.5

—

(42870588) Differential panel, method unspecified - Blood

109

1.43

0.40

7.4

6.5

—

(40761511) CBC panel - Blood by Automated count

344

1.63

0.40

21.8

14.1

—

(3009542) Hematocrit [Volume Fraction] of Blood

288

1.47

0.40

26.9

15.0

39.2

40.5

0.62

214

(3044889) 12 lead EKG panel

242

0.74

0.37

3.3

4.0

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

337

0.69

0.36

4.1

4.9

2.7

mmol/l

0.13

315

(1761868) Lipid panel - Serum or Plasma

130

1.37

0.36

2.9

2.8

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.35

0.32

1.9

2.9

11.8

16.2

umol/l

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

357

0.75

0.30

15.3

10.3

25.4

26.0

u/l

0.09

348

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.39

0.29

2.1

2.3

—

(3022096) Basophils/100 leukocytes in Blood

154

1.30

0.27

7.7

6.5

0.5

0.7

0.81

139

(3037467) Urinalysis macro (dipstick) panel - Urine

225

1.27

0.25

5.2

4.7

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

1.25

0.23

2.0

3.4

2.6

1.4

—

(3006504) Eosinophils/100 leukocytes in Blood

157

1.26

0.23

7.8

6.6

2.1

2.7

0.86

143

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

3.2

—

2.2

—

(3020961) Endomysium IgA Ab [Titer] in Serum

0.00

0.21

0.0

1.1

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

0.21

0.0

1.1

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

0.21

0.0

1.1

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

0.21

0.0

1.1

—

(3021387) Prolactin [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

362.6

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.21

0.0

1.0

—

(1002224) Polysomnography panel

0.00

0.20

0.0

1.0

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.00

0.20

0.0

1.1

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.20

0.0

1.4

—

(3026008) Bacteria identified in Urine by Culture

1.28

0.20

4.6

3.4

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

140

1.23

0.19

6.2

3.8

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

342

1.37

0.17

25.1

16.4

139.5

139.8

mmol/l

0.30

335

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

0.78

0.17

1.5

1.4

3.7

0.8

mg/l

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

346

1.28

0.17

25.2

16.4

4.1

4.0

mmol/l

0.85

339

(3019069) Monocytes/100 leukocytes in Blood

161

1.21

0.17

7.9

6.8

8.0

8.9

0.89

148

(36304419) Bacteria [Presence] in Urine

1.20

0.12

3.4

3.0

—

(3002030) Lymphocytes/100 leukocytes in Blood

165

1.16

0.11

7.8

6.6

29.8

27.9

0.26

151

(40768797) Stomach Pathology biopsy report

1.13

0.10

1.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.10

0.10

1.6

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

0.79

0.08

4.3

3.6

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

268

1.13

0.07

11.8

7.2

72.1

78.7

u/l

0.48

255

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

119

1.13

0.07

3.1

4.2

18.6

21.0

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

310

0.89

0.06

5.7

4.8

5.8

6.0

mmol/l

0.51

291

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

119

1.01

0.00

3.8

3.0

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

133

0.97

0.00

2.3

2.8

144.8

148.5

ug/l

0.03

125

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

154

0.96

0.00

6.1

4.5

2.5

2.4

ug/l

0.06

138

(3018010) Neutrophils/100 leukocytes in Blood

162

0.98

0.00

6.3

55.3

57.4

0.42

149

(3012441) Differential panel - Pleural fluid

0.00

0.0

1.5

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

354

1.12

0.00

27.6

16.9

75.5

85.4

umol/l

1.85

354

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

1.00

0.00

4.3

3.1

16.8

41.9

ng/l

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

0.0

1.4

—

5.8

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(3024172) Erythropoietin (EPO) [Units/volume] in Serum or Plasma

0.00

0.0

1.2

—

13.2

—

(3013512) EKG study

0.95

0.00

5.6

4.0

—

(3034770) Mitochondria Ab [Titer] in Serum

0.00

0.0

1.0

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

0.0

1.5

—

157.8

—

(3032836) C peptide [Moles/volume] in Serum or Plasma --fasting

0.00

0.0

1.0

—

0.9

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.0

1.7

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

323

1.10

0.00

20.8

13.4

83.3

79.7

ml/min/173m2

0.58

268

(3035941) MCH [Entitic mass]

370

1.00

0.00

33.6

21.4

30.0

30.4

0.55

364

(3003181) Sodium [Moles/volume] in Urine

0.00

0.0

1.0

—

83.4

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

7.2

—

(3010813) Leukocytes [#/volume] in Blood

370

1.00

0.00

34.9

21.6

7.9

6.7

e9/l

2.49

362

(3000963) Hemoglobin [Mass/volume] in Blood

370

1.00

0.00

34.1

21.6

130.9

136.4

g/l

1.25

364

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

0.0

2.3

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.4

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.3

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.0

1.4

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

0.00

0.0

1.2

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

1.3

—

(3024731) MCV [Entitic volume]

370

1.00

0.00

33.7

21.5

90.7

91.4

0.27

364

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.0

1.7

—

(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.4

—

13.4

—

(42870365) C reactive protein [Mass/volume] in Blood by High sensitivity method

0.00

0.0

1.8

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.0

—

(3026361) Erythrocytes [#/volume] in Blood

370

1.00

0.00

33.6

21.5

4.4

4.5

e12/l

0.45

362

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

0.0

2.1

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.0

2.8

—

(3037756) Immunofixation for Serum or Plasma

0.00

0.0

1.5

—

(3007461) Platelets [#/volume] in Blood

370

1.00

0.00

33.8

21.5

248.2

246.3

e9/l

0.06

362

(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid

0.00

0.0

1.4

—

8.6

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.0

1.2

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

0.0

1.7

—

25.5

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

190

1.00

0.00

2.6

3.4

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

2.5

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: ST19_TRAUMAT_SUBCU_EMPHY – Traumatic subcutaneous emphysema

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Traumatic subcutaneous emphysema

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Traumatic subcutaneous emphysema (ST19_TRAUMAT_SUBCU_EMPHY)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Relationships between endpoints