Immunodeficiency with predominantly antibody defects

D3_IMMUDEFANTIBODY

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D80
  • Cause of death: ICD-10 D80

2 out of 7 registries used, show all original rules.

932

4. Check minimum number of events

None

932

5. Include endpoints

959

6. Filter based on genotype QC (FinnGen only)

959

Control definitions (FinnGen only)

Control exclude
D3_IMMUNEMECHANISM

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D80-D89
Name in latin
Deficientia immunalis praecipue cum vitiis anticorporum

Similar endpoints

List of similar endpoints to Immunodeficiency with predominantly antibody defects based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4354 2534 1806
Only index persons 3907 2323 1584
Unadjusted period prevalence (%)
Whole population 0.06 0.07 0.05
Only index persons 0.08 0.09 0.06
Median age at first event (years)
Whole population 41.53 44.86 36.81
Only index persons 41.99 45.45 36.90

-FinnGen-

Key figures

All Female Male
Number of individuals 959 631 328
Unadjusted period prevalence (%) 0.19 0.22 0.14
Median age at first event (years) 48.60 47.78 50.17

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
872
Matched controls
8717
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
+∞
323.0
329
*
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
+∞
277.3
251
*
120
Kela drug reimbursment
Hypogammaglobulinaemia
+∞
245.8
224
*
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
2764.7
242.3
223
*
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
+∞
229.6
210
*
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
+∞
204.4
188
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
22.0
156.6
237
145
ZX120
NOMESCO Finland
Intravenous
12.0
156.2
318
399
H02AB06
ATC
prednisolone; systemic
6.7
140.7
663
2792
D80.2
ICD-10 Finland
Selective deficiency of immunoglobulin A [IgA]
1551.4
139.5
132
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.3
137.0
606
2319
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
16.5
130.0
219
173
J01MA12
ATC
levofloxacin; systemic
7.4
128.5
371
796
J01MA14
ATC
moxifloxacin; systemic
10.6
123.9
264
343
J18.9
ICD-10 Finland
Pneumonia, unspecified
6.6
123.0
394
963
D80.0
ICD-10 Finland
Hereditary hypogammaglobulinaemia
+∞
119.6
112
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
10.6
118.8
252
322
6BA02
NOMESCO Finland
NA
264.4
114.8
115
5
WW200
NOMESCO Finland
Immunization
22.4
114.8
171
94
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
16.0
101.7
172
132
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
21.1
101.0
153
87
TPH04
NOMESCO Finland
Cathetrisation of vein
5.5
98.5
365
1008
TDM10
NOMESCO Finland
Puncture of maxillary antrum
13.4
93.5
171
156
R50.9
ICD-10 Finland
Fever, unspecified
5.9
88.9
294
694
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
10.4
88.1
184
218
J47
ICD-10 Finland
Bronchiectasis
32.9
87.0
115
40
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
6.0
86.8
277
623
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
9.0
83.9
192
266
H02AB07
ATC
prednisone; oral
5.7
80.4
270
638
J01.0
ICD-10 Finland
Acute maxillary sinusitis
4.4
79.8
375
1268
J45.1
ICD-10 Finland
Nonallergic asthma
8.4
78.4
187
275
J45.9
ICD-10 Finland
Asthma, unspecified
4.9
77.5
310
886
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.1
75.1
390
1427
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
8.2
74.1
178
263
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
13.0
74.1
136
122
R03DC03
ATC
montelukast; oral
4.7
73.3
301
875
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
4.6
72.4
310
939
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
4.8
71.3
286
808
J01FA06
ATC
roxithromycin; oral
3.6
69.4
505
2410
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.7
67.3
404
1634
J45.0
ICD-10 Finland
Predominantly allergic asthma
6.0
67.3
208
434
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.3
66.6
195
379
R03BA02
ATC
budesonide; inhalant
4.2
61.9
286
908
TGC00
NOMESCO Finland
Bronchial lavation
16.2
61.1
101
70
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.4
60.5
154
244
UDH02
NOMESCO Finland
Rhinopharyngoscopy
7.1
60.4
160
269
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
3.3
59.3
602
3507
D83.9
ICD-10 Finland
Common variable immunodeficiency, unspecified
+∞
59.0
56
*
XW000
NOMESCO Finland
Bone marrow biopsy
11.6
58.8
113
110
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
7.5
57.3
144
223
C01CA24
ATC
epinephrine; parenteral
6.0
53.5
161
318
R03AC02
ATC
salbutamol; inhalant
3.1
53.4
589
3507
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
3.0
52.7
542
3066
J01FA10
ATC
azithromycin; systemic
3.1
50.9
646
4159
J01MA02
ATC
ciprofloxacin; systemic
3.0
50.7
426
2084
R03BB04
ATC
tiotropium bromide; inhalant
5.4
50.4
165
359
H02AB04
ATC
methylprednisolone; systemic
4.1
49.8
226
687
R03AK06
ATC
salmeterol and fluticasone; inhalant
4.1
49.3
220
658
D83.0
ICD-10 Finland
Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
+∞
48.4
46
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
9.4
47.9
103
123
Z01.8
ICD-10 Finland
Other specified special examinations
3.3
47.1
297
1174
H02AB09
ATC
hydrocortisone; systemic
11.3
47.0
91
89
J01FF01
ATC
clindamycin; systemic
3.1
46.9
339
1476
C03CA01
ATC
furosemide; systemic
3.5
46.5
270
1001
J32.4
ICD-10 Finland
Chronic pansinusitis
20.1
45.7
69
37
R03AC12
ATC
salmeterol; inhalant
8.2
45.1
105
143
J01FA09
ATC
clarithromycin; systemic
2.9
44.5
388
1897
JN4BD
NOMESCO Finland
Extensive body CT
4.6
43.4
167
428
D80.6
ICD-10 Finland
Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
+∞
43.1
41
*
R01AD09
ATC
mometasone; nasal
2.7
42.6
505
2948
A07AA02
ATC
nystatin; oral
6.6
42.5
115
195
J46
ICD-10 Finland
Status asthmaticus
10.3
42.1
85
90
R4110
NOMESCO Finland
Physiotherapy
3.0
42.1
324
1449
A03FA01
ATC
metoclopramide; systemic, rectal
3.2
41.3
263
1030
R03BA05
ATC
fluticasone; inhalant
3.2
41.1
258
1000
R06.0
ICD-10 Finland
Dyspnoea
3.1
41.0
279
1143
L03AA02
ATC
filgrastim; parenteral
10.9
40.8
80
80
ZX108
NOMESCO Finland
Inhalation
36.8
40.8
52
15
R01AD08
ATC
fluticasone; nasal
2.8
40.8
355
1707
ZXA10
NOMESCO Finland
Bilateral
3.4
40.8
237
866
R03BB01
ATC
ipratropium bromide; inhalant
9.7
40.6
85
96
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
5.0
40.5
142
329
J05AB11
ATC
valaciclovir; oral
3.7
40.0
200
648
R03AC13
ATC
formoterol; inhalant
6.9
39.4
103
166
R03DA04
ATC
theophylline; systemic, rectal
7.1
38.9
100
157
D84.18
ICD-10 Finland
Other specified defect in the complement system
+∞
38.8
37
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.7
38.7
190
604
J01FA15
ATC
telithromycin; oral
4.0
38.7
173
508
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.8
38.6
334
1586
M05BA04
ATC
alendronic acid; oral
5.3
37.2
122
261
WW500
NOMESCO Finland
Blood transfusion
7.9
37.2
88
122
J01DB01
ATC
cefalexin; oral
3.4
36.4
772
6068
J01AA02
ATC
doxycycline; systemic
2.9
36.4
719
5385
N02AX02
ATC
tramadol; systemic, rectal
2.5
36.3
424
2372
R03AK07
ATC
formoterol and budesonide; inhalant
3.1
36.2
238
940
A02BC02
ATC
pantoprazole; systemic
2.5
36.1
603
4084
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
5.5
35.8
112
227
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
25.2
35.7
50
21
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
6.4
35.4
98
170
WE300
NOMESCO Finland
Profylactive therapy of malignancy with biomoidiers
361.0
35.2
35
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.2
35.2
221
843
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
19.4
34.8
53
29
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
34.4
318
1548
R01AD05
ATC
budesonide; nasal
4.3
34.3
137
359
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.6
34.3
105
207
TAB00
NOMESCO Finland
Lumbar puncture
6.2
34.1
96
170
XG410
NOMESCO Finland
Flow-volume spirometry
7.2
33.8
85
129
J02AC01
ATC
fluconazole; systemic
2.4
33.6
447
2640
XF400
NOMESCO Finland
ECG with 12 standard connections
3.2
33.5
206
771
GD1AD
NOMESCO Finland
Thorax CT examination
7.2
33.2
83
125
R05
ICD-10 Finland
Cough
2.9
33.1
239
996
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.1
32.9
138
379
R03BA08
ATC
ciclesonide; inhalant
4.3
32.6
131
345
J45.8
ICD-10 Finland
Mixed asthma
7.7
32.6
78
110
H04.10
ICD-10 Finland
Dry eye syndrome
3.9
32.4
144
416
UJF32
NOMESCO Finland
Coloscopy
2.7
32.2
275
1270
A41.9
ICD-10 Finland
Sepsis, unspecified
7.9
32.1
75
102
UJF30
NOMESCO Finland
Ileoscopy through colon
4.0
32.1
140
398
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.1
31.9
136
378
D84.9
ICD-10 Finland
Immunodeficiency, unspecified
+∞
31.4
30
*
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
27.5
30.8
42
16
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
8.9
30.8
67
81
XQ800
NOMESCO Finland
Prick test
3.9
30.7
139
407
M04AA01
ATC
allopurinol; systemic
3.9
30.5
137
398
N03AX16
ATC
pregabalin; oral
2.6
29.4
257
1191
M36.8*D80.1
ICD-10 Finland
Systemic disorders of connective tissue in hypogammaglobulinaemia
+∞
29.3
28
*
J01DA06
ATC
[U] cefuroxime; systemic
3.0
29.0
190
736
N02AA05
ATC
oxycodone; systemic
3.4
28.9
159
543
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
5.4
28.8
90
181
R03AK08
ATC
formoterol and beclometasone; inhalant
6.3
28.7
79
136
R03DC01
ATC
zafirlukast; oral
14.0
28.5
49
37
D86.0
ICD-10 Finland
Sarcoidosis of lung
+∞
28.3
27
*
R01AD12
ATC
fluticasone furoate; nasal
2.3
28.1
345
1904
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.3
28.0
386
2254
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
16.3
27.9
45
29
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
14.1
27.5
47
35
D70.82
ICD-10 Finland
Drug-induced neutropenia
10.6
27.1
53
53
J31.0
ICD-10 Finland
Chronic rhinitis
3.9
26.9
120
345
ZXA00
NOMESCO Finland
Right side
2.5
26.9
272
1354
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
17.6
26.9
42
25
WZC30
NOMESCO Finland
Teaching
3.1
26.7
165
608
ZX112
NOMESCO Finland
Subcutaneous
8.9
26.4
57
68
J05AB01
ATC
aciclovir; systemic
2.6
26.4
240
1126
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
10.0
26.3
53
56
R03AK11
ATC
formoterol and fluticasone; inhalant
8.8
26.2
57
69
L04AX01
ATC
azathioprine; systemic
4.9
26.0
89
198
R03AC03
ATC
terbutaline; inhalant
3.0
26.0
173
671
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.5
25.4
94
227
R03BA01
ATC
beclometasone; inhalant
2.9
25.4
174
689
L04AA06
ATC
mycophenolic acid; systemic
10.7
25.3
49
48
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.9
25.2
172
677
D86.2
ICD-10 Finland
Sarcoidosis of lung with sarcoidosis of lymph nodes
+∞
25.1
24
*
A01AB09
ATC
miconazole; local oral
3.7
25.0
117
350
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
28.5
24.6
33
12
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.9
24.5
167
657
J20
ICD-10 Finland
Acute bronchitis
3.4
24.4
128
420
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.4
24.2
128
422
1XC02
NOMESCO Finland
NA
23.5
24.0
34
15
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
8.0
23.9
55
73
A04AA01
ATC
ondansetron; systemic, rectal
4.0
23.7
99
268
R06AE07
ATC
cetirizine; oral
2.1
23.6
445
2910
A02BC05
ATC
esomeprazole; systemic
2.1
23.6
383
2352
J01DA01
ATC
[U] cefalexin; systemic
2.1
23.6
580
4233
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
23.5
371
2249
TPX10
NOMESCO Finland
Implantation of vascular injection port
6.8
23.4
60
94
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
22.8
23.1
33
15
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.9
22.9
58
89
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
11.2
22.8
43
40
P01AB01
ATC
metronidazole; oral, rectal
2.1
22.5
386
2412
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
4.8
22.5
78
176
R01BA52
ATC
pseudoephedrine, combinations; oral
2.2
22.3
316
1818
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
22.1
22.3
32
15
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.9
22.2
97
273
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
22.1
122
413
2790B
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[DEFICIENTIA IMMUNOGLOBULINI A]
+∞
22.0
21
*
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
+∞
22.0
21
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.6
21.9
106
325
J45
ICD-10 Finland
Asthma
3.1
21.7
128
456
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
7.2
21.6
53
78
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
5.4
21.5
66
130
D70.89
ICD-10 Finland
Neutropenic splenomegaly
12.8
21.5
38
31
S01GX01
ATC
cromoglicic acid; ophthalmic
2.3
21.4
231
1168
SPAT1262
SPAT
Handing over of treatment supplies
2.6
21.3
182
811
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.1
21.3
341
2057
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
7.4
21.2
51
73
D64.9
ICD-10 Finland
Anaemia, unspecified
3.5
21.1
104
323
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.4
21.1
109
352
A02BC01
ATC
omeprazole; systemic
2.2
20.9
262
1418
D83.8
ICD-10 Finland
Other common variable immunodeficiencies
+∞
20.9
20
*
XG474
NOMESCO Finland
Exhalation nntrogen oxide
6.0
20.9
59
105
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
8.7
20.9
45
54
GD1DG
NOMESCO Finland
Extremely extensive MRI examination of pleura with high field magnet
214.9
20.7
21
*
L03AA13
ATC
pegfilgrastim; parenteral
5.4
20.6
63
124
JN4AD
NOMESCO Finland
Body CT examination
3.7
20.3
94
278
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.0
20.2
127
470
J01DA08
ATC
[U] cefaclor; oral
2.7
20.1
148
606
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.3
20.1
108
359
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
4.8
20.0
68
150
XA800
NOMESCO Finland
Neuropsychological investigation
4.3
20.0
77
193
WX002
NOMESCO Finland
Sedation and analgesia
2.4
19.9
198
957
N03AX12
ATC
gabapentin; oral
2.5
19.9
169
752
N02BE01
ATC
paracetamol; systemic, rectal
2.3
19.8
745
6232
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
9.7
19.8
40
43
A46
ICD-10 Finland
Erysipelas
2.8
19.7
135
527
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.8
19.6
139
555
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
22.2
19.6
28
13
ZXA05
NOMESCO Finland
Left side
2.2
19.6
233
1225
N05CF01
ATC
zopiclone; oral
2.1
19.5
289
1671
127
Kela drug reimbursment
Transplant complication
8.9
19.3
41
48
R81
ICPC
Pneumonia
5.7
19.2
56
104
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
23.2
19.1
27
12
ZX121
NOMESCO Finland
Central venous catheter
23.2
19.1
27
12
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
3.0
19.1
121
449
E0000UV
ATC
NA
2.0
19.0
384
2505
N05BA01
ATC
diazepam; systemic, rectal
2.7
19.0
142
586
B29
ICPC
Lymph/immune mech sympt/complt other
35.2
19.0
24
7
J32.1
ICD-10 Finland
Chronic frontal sinusitis
35.2
19.0
24
7
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.1
19.0
295
1740
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.9
19.0
124
470
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
18.9
160
706
J01.4
ICD-10 Finland
Acute pansinusitis
16.3
18.9
30
19
2790C
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[DEFICIENTIA IMMUNOGLOBULINI ALIA]
+∞
18.8
18
*
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
+∞
18.8
18
*
P01BA02
ATC
hydroxychloroquine; oral
3.1
18.7
109
381
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
18.4
132
530
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
6.0
18.4
51
89
N06AX21
ATC
duloxetine; oral
2.7
18.3
132
533
A41.8
ICD-10 Finland
Other specified sepsis
10.1
18.3
36
37
R06AE09
ATC
levocetirizine; oral
2.4
18.1
171
801
ZX114
NOMESCO Finland
Intramuscular
7.7
18.1
42
57
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.5
18.1
89
276
A02BC03
ATC
lansoprazole; oral
2.1
18.0
264
1511
R51.80
ICD-10 Finland
Headache
2.4
17.8
169
793
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.0
17.8
109
393
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
5.5
17.8
53
101
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.9
17.6
111
411
UDM02
NOMESCO Finland
Sinoscopy
6.3
17.6
47
78
SPAT1255
SPAT
Intravenous administration of medicine
3.8
17.6
78
222
A01AB04
ATC
amphotericin B; local oral
4.7
17.6
61
138
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
4.9
17.5
58
125
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.6
17.4
143
620
WX892
NOMESCO Finland
Monitored bed care
3.2
17.3
93
309
J01.1
ICD-10 Finland
Acute frontal sinusitis
7.4
17.2
41
58
X59
ICD-10 Finland
Exposure to unspecified factor
2.2
17.1
192
977
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
10.3
17.0
33
33
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
26.2
17.0
23
9
J01CA04
ATC
amoxicillin; systemic
2.2
16.9
736
6234
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
14.4
16.9
28
20
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.3
16.9
182
905
D80.4
ICD-10 Finland
Selective deficiency of immunoglobulin M [IgM]
+∞
16.7
16
*
J06BA02
ATC
immunoglobulins, normal human, for intravascular adm.; systemic
+∞
16.7
16
*
L04AA13
ATC
leflunomide; oral
5.9
16.7
47
84
A28
ICPC
Limited function/disability NOS
2.7
16.6
119
477
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
6.7
16.6
42
65
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
16.6
172
840
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.7
16.6
125
517
H65.2
ICD-10 Finland
Chronic serous otitis media
7.7
16.6
38
51
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
28.2
16.6
22
8
L01BB05
ATC
fludarabine; systemic
173.1
16.5
17
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.2
16.5
88
291
R06AX27
ATC
desloratadine; oral
1.9
16.2
287
1759
Z50.1
ICD-10 Finland
Other physical therapy
3.8
16.1
70
196
B99
ICD-10 Finland
Other and unspecified infectious diseases
7.9
16.0
36
47
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
8.2
15.9
35
44
L04AA01
ATC
[U] ciclosporin; systemic
7.5
15.9
37
51
GD1CG
NOMESCO Finland
Extensive examination of lungs and pleura with high intensity magnet
61.2
15.8
18
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.8
15.8
108
421
B28
ICPC
Limited function/disability (B)
34.1
15.8
20
6
D84.1
ICD-10 Finland
Defects in the complement system
+∞
15.7
15
*
N06AA09
ATC
amitriptyline; systemic
2.8
15.6
105
402
SPAT1325
SPAT
Vaccination
1.9
15.6
296
1853
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
2.0
15.6
226
1279
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
15.5
387
2657
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
15.5
218
1216
DPA25
NOMESCO Finland
Trephine of frontal sinus through nose
15.1
15.4
25
17
B01AB05
ATC
enoxaparin; parenteral
2.0
15.3
258
1542
J33.8
ICD-10 Finland
Other polyp of sinus
7.3
15.2
36
51
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.5
15.2
123
529
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.7
15.2
68
196
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
5.5
15.2
45
86
J32.8
ICD-10 Finland
Other chronic sinusitis
23.9
15.2
21
9
R03BC03
ATC
nedocromil; inhalant
3.2
15.1
84
283
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.5
15.0
122
526
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
12.7
14.9
26
21
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
10.7
14.8
28
27
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.2
14.8
177
921
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
25.5
14.7
20
8
R74
ICPC
Upper respiratory infection acute
1.9
14.7
290
1832
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.1
14.7
58
150
D86.1
ICD-10 Finland
Sarcoidosis of lymph nodes
+∞
14.6
14
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
14.5
215
1220
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
6.4
14.5
38
62
L04AD01
ATC
ciclosporin; systemic
5.9
14.5
40
70
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
17.3
14.3
22
13
A07AA09
ATC
vancomycin; oral
10.7
14.3
27
26
H66.9
ICD-10 Finland
Otitis media, unspecified
3.0
14.3
86
308
R01AD01
ATC
beclometasone; nasal
2.2
14.3
157
784
J01FA01
ATC
erythromycin; systemic
2.2
14.3
155
770
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
22.7
14.3
20
9
H65.3
ICD-10 Finland
Chronic mucoid otitis media
4.7
14.2
48
106
WX872
NOMESCO Finland
Intensive care
3.9
14.0
58
156
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
30.6
13.9
18
6
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.1
13.9
169
883
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.9
13.9
267
1666
A06AD11
ATC
lactulose; oral
2.5
13.9
115
500
DPA20
NOMESCO Finland
Trephine of frontal sinus
54.2
13.8
16
*
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
20.4
13.8
20
10
M05BB03
ATC
alendronic acid and colecalciferol; oral
6.3
13.8
36
59
TQW99
NOMESCO Finland
Other minor procedure on skin
3.9
13.7
57
154
A04AA02
ATC
granisetron; systemic, transdermal
3.4
13.7
67
207
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.0
13.7
55
144
XF600
NOMESCO Finland
Bloodpressure measurement
3.1
13.7
78
269
J01DC02
ATC
cefuroxime; systemic
3.1
13.7
75
253
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.9
13.7
253
1555
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.5
13.7
116
510
Z71.8
ICD-10 Finland
Other specified counselling
1.9
13.7
228
1349
C82.1
ICD-10 Finland
Follicular lymphoma grade II
15.0
13.6
22
15
D83.1
ICD-10 Finland
Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
+∞
13.6
13
*
L01XE27
ATC
[U] ibrutinib; oral
+∞
13.6
13
*
132
Kela drug reimbursment
Sarcoidosis
+∞
13.6
13
*
D84.19
ICD-10 Finland
Unspecified defect in the complement system
+∞
13.6
13
*
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.9
13.6
251
1544
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.9
13.6
86
318
N05CD07
ATC
temazepam; oral
2.6
13.5
106
446
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.0
13.3
180
984
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
13.3
129
608
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
7.0
13.2
32
47
S97
ICPC
Chronic ulcer skin
3.9
13.2
55
149
UJF92
NOMESCO Finland
Capsular endoscopy
5.4
13.1
39
75
TK800
NOMESCO Finland
Hemodialysis
6.4
13.1
34
55
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.7
13.1
91
355
R53
ICD-10 Finland
Malaise and fatigue
2.0
13.0
189
1060
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.0
13.0
79
284
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
7.5
13.0
30
41
WW300
NOMESCO Finland
Transfer of autologic stem cells
17.0
13.0
20
12
ZX110
NOMESCO Finland
Intracutaneous
28.8
13.0
17
6
JN3AD
NOMESCO Finland
Abdominal CT examination
2.9
13.0
83
309
J33.0
ICD-10 Finland
Polyp of nasal cavity
5.5
13.0
38
72
C07AB07
ATC
bisoprolol; oral
1.7
13.0
342
2352
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.3
12.9
133
641
L28
ICPC
Limited function/disability (L)
2.3
12.9
133
642
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.5
12.9
104
445
3XA02
NOMESCO Finland
NA
50.8
12.9
15
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
4.1
12.8
50
128
R1250
NOMESCO Finland
Evaluation of functional capability
4.7
12.8
43
95
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
10.7
12.8
24
23
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
10.7
12.8
24
23
E86
ICD-10 Finland
Volume depletion
6.9
12.8
31
46
M81.9
ICD-10 Finland
Osteoporosis, unspecified
4.5
12.7
45
105
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.9
12.7
78
284
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
3.7
12.7
56
160
R4120
NOMESCO Finland
Occupational therapy
3.0
12.7
74
261
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
12.5
12.7
22
18
C10AC01
ATC
colestyramine; oral
4.5
12.6
44
101
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
32.5
12.6
16
5
A03
ICPC
Fever
2.0
12.5
171
935
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
20.4
12.5
18
9
R96
ICPC
Asthma
2.6
12.4
91
369
3AC01
NOMESCO Finland
NA
8.2
12.4
27
34
DPA30
NOMESCO Finland
Sphenotomy
14.6
12.3
20
14
RD210
NOMESCO Finland
NA
4.8
12.3
40
86
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.9
12.2
50
134
J01.9
ICD-10 Finland
Acute sinusitis, unspecified
3.9
12.2
50
134
M35.7
ICD-10 Finland
Hypermobility syndrome
6.2
12.2
32
53
B03XA02
ATC
darbepoetin alfa; parenteral
7.9
12.2
27
35
J96.0
ICD-10 Finland
Acute respiratory failure
12.6
12.2
21
17
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
12.1
384
2774
M05BA07
ATC
risedronic acid; oral
5.2
12.1
37
74
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.7
12.1
52
146
H02AB02
ATC
dexamethasone; systemic
2.5
12.1
95
401
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
6.1
12.0
32
54
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
10.2
12.0
23
23
I50.9
ICD-10 Finland
Heart failure, unspecified
2.8
12.0
81
310
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.6
12.0
88
355
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.4
12.0
101
443
A07EA06
ATC
budesonide; oral, local oral
3.9
11.9
49
132
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
47.3
11.9
14
*
390
Kela drug reimbursment
Ibrutinib
47.3
11.9
14
*
R06AX22
ATC
ebastine; oral
2.0
11.9
175
985
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
11.9
11.9
21
18
C03DA01
ATC
spironolactone; oral
2.6
11.8
88
360
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
4.8
11.8
39
85
50301
ICD-8 Finland
Chronic sinusitis, Maxillaris NUD
9.8
11.8
23
24
N19
ICD-10 Finland
Unspecified kidney failure
6.1
11.7
31
52
H26.3
ICD-10 Finland
Drug-induced cataract
16.7
11.7
18
11
WX722
NOMESCO Finland
PEEP
3.5
11.7
54
161
A02BA02
ATC
ranitidine; systemic
2.0
11.6
162
888
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
19.2
11.6
17
9
J01
ICD-10 Finland
Acute sinusitis
3.1
11.6
65
221
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
11.3
11.6
21
19
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
11.5
314
2163
4222
FHL
Endonasal etmoidectomy
13.8
11.5
19
14
DMB10
NOMESCO Finland
Radical maxillary antrotomy
15.3
11.3
18
12
318
Kela drug reimbursment
Teriparatide
15.3
11.3
18
12
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
17.3
11.2
17
10
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.7
11.2
80
318
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
12.9
11.2
19
15
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
25.4
11.2
15
6
L01AA01
ATC
cyclophosphamide; systemic
20.3
11.2
16
8
N03AX11
ATC
topiramate; oral
4.1
11.1
43
110
B34.9
ICD-10 Finland
Viral infection, unspecified
4.1
11.1
43
110
R06AX13
ATC
loratadine; oral
2.0
11.1
158
873
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
5.0
11.1
35
73
J18.1
ICD-10 Finland
Lobar pneumonia, unspecified
9.4
11.0
22
24
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.7
11.0
47
131
R01BA01
ATC
phenylpropanolamine; oral
3.0
11.0
63
219
XCK10
NOMESCO Finland
Photography of fundus of eye
2.5
11.0
91
394
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.1
11.0
60
203
DHB50
NOMESCO Finland
Turbinoplasty
4.6
11.0
37
83
R05
ICPC
Cough
1.9
10.9
196
1180
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.3
10.9
106
497
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
4.7
10.9
36
79
J01EA01
ATC
trimethoprim; systemic
1.8
10.9
211
1304
EB1WA
NOMESCO Finland
NA
12.1
10.9
19
16
H05AA02
ATC
teriparatide; parenteral
15.7
10.9
17
11
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.5
10.8
50
149
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.3
10.8
103
478
R06AX26
ATC
fexofenadine; oral
2.7
10.8
74
287
E87.6
ICD-10 Finland
Hypokalaemia
4.4
10.8
38
89
4930B
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA CUM EXACERBATIONE]
9.7
10.8
21
22
R02
ICPC
Shortness of breath/dyspnoea
2.3
10.8
105
493
R11
ICD-10 Finland
Nausea and vomiting
2.5
10.7
84
353
WX882
NOMESCO Finland
High dependency care
3.8
10.7
45
124
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
7.7
10.7
24
32
XG466
NOMESCO Finland
Sleep oxymetry
4.0
10.7
42
109
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
4.8
10.7
35
76
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
6.4
10.7
27
43
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.6
10.6
80
329
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.9
10.5
42
111
J05AB09
ATC
famciclovir; oral
14.4
10.5
17
12
UJD02
NOMESCO Finland
Gastroscopy
3.3
10.5
52
164
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
6.0
10.5
28
48
TPH07
NOMESCO Finland
Cathetrisation of artery
2.4
10.5
89
392
2790A
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[AGAMMAGLOBULINAEMIA (BRUTON)]
+∞
10.4
10
*
D81.0
ICD-10 Finland
Severe combined immunodeficiency [SCID] with reticular dysgenesis
+∞
10.4
10
*
D80.5
ICD-10 Finland
Immunodeficiency with increased immunoglobulin M [IgM]
+∞
10.4
10
*
UKC02
NOMESCO Finland
Cystoscopy
2.2
10.4
114
563
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
6.5
10.4
26
41
C90.0
ICD-10 Finland
Multiple myeloma
12.2
10.4
18
15
C83.00
ICD-10 Finland
Lymphocytic lymphoma
32.9
10.3
13
*
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
6.2
10.3
27
45
A07EC01
ATC
sulfasalazine; oral, rectal
2.5
10.3
84
359
N30.0
ICD-10 Finland
Acute cystitis
2.1
10.3
124
641
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
7.6
10.2
23
31
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.8
10.2
42
114
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.0
10.2
58
201
H92.0
ICD-10 Finland
Otalgia
2.8
10.1
64
238
C08DA01
ATC
verapamil; systemic
3.7
10.1
44
125
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
5.1
10.1
31
63
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.5
10.1
35
81
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
11.5
10.1
18
16
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.7
10.0
43
121
XX3DW
NOMESCO Finland
Time consuming IT work
2.3
10.0
91
414
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.6
10.0
34
77
K90.0
ICD-10 Finland
Coeliac disease
3.8
10.0
41
111
1512
Kela drug reimbursment
Ibrutinib
40.5
10.0
12
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
6.8
9.9
24
36
JN6AD
NOMESCO Finland
CT of torso and neck
6.8
9.9
24
36
AA1AD
NOMESCO Finland
CT of head and brain
1.8
9.9
178
1065
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
9.9
206
1294
RS221
NOMESCO Finland
NA
5.1
9.9
30
60
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
3.3
9.9
48
149
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.6
9.9
73
297
K29.3
ICD-10 Finland
Chronic superficial gastritis
4.0
9.9
39
102
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
16.9
9.9
15
9
B01AB04
ATC
dalteparin; parenteral
3.4
9.9
47
144
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
6.1
9.9
26
44
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
7.1
9.8
23
33
G44.2
ICD-10 Finland
Tension-type headache
2.0
9.8
130
696
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
9.8
196
1219
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
9.7
9.8
19
20
XCK00
NOMESCO Finland
Perimetry
2.7
9.8
65
249
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.9
9.8
58
208
ZX100
NOMESCO Finland
Oral
6.6
9.8
24
37
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.7
9.7
41
114
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
4.5
9.7
33
75
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.3
9.7
47
146
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
13.6
9.7
16
12
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
5.0
9.7
30
62
UDC00
NOMESCO Finland
Ear microscopy
2.6
9.6
71
290
J32.2
ICD-10 Finland
Chronic ethmoidal sinusitis
8.5
9.6
20
24
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
11.5
9.6
17
15
R75
ICPC
Sinusitis acute/chronic
3.1
9.6
52
176
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.2
9.6
49
159
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.2
9.6
49
159
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.4
9.6
85
382
R49.01
ICD-10 Finland
Functional dysphonia
3.6
9.5
42
122
M79.6
ICD-10 Finland
Pain in limb
1.6
9.5
300
2125
M31.1
ICD-10 Finland
Thrombotic microangiopathy
101.1
9.4
10
*
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
4.1
9.4
35
87
K90.9
ICD-10 Finland
Intestinal malabsorption, unspecified
17.8
9.4
14
8
YNB10
NOMESCO Finland
Collection of stem cells for transplant
17.8
9.4
14
8
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
30.4
9.4
12
*
D84.8
ICD-10 Finland
Other specified immunodeficiencies
+∞
9.4
9
*
D81.1
ICD-10 Finland
Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
+∞
9.4
9
*
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
+∞
9.4
9
*
5BA08
NOMESCO Finland
NA
12.5
9.4
16
13
R5140
NOMESCO Finland
Monitoring the use of the aid
2.3
9.4
91
426
X57
ICD-10 Finland
Unspecified privation
4.6
9.3
31
69
R01BA51
ATC
phenylpropanolamine, combinations; oral
2.0
9.3
121
644
B03BA03
ATC
hydroxocobalamin; parenteral
3.1
9.3
50
168
H01
ICPC
Ear pain/earache
2.1
9.3
107
543
J05AH02
ATC
oseltamivir; oral
9.6
9.3
18
19
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
9.6
9.3
18
19
N06AX11
ATC
mirtazapine; oral
1.7
9.3
262
1798
N06AX16
ATC
venlafaxine; oral
2.0
9.3
132
730
R52.9
ICD-10 Finland
Pain, unspecified
2.4
9.2
78
343
R4190
NOMESCO Finland
Nutritional therapy
3.2
9.2
47
153
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
4.1
9.1
34
85
R42
ICD-10 Finland
Dizziness and giddiness
1.8
9.1
157
929
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.4
9.1
74
318
TKC20
NOMESCO Finland
Catheterisation of bladder
2.8
9.1
58
218
Z49.1
ICD-10 Finland
Extracorporeal dialysis
7.1
9.1
21
30
M05BX04
ATC
denosumab; parenteral
3.1
9.1
48
160
TK810
NOMESCO Finland
Hemofiltration
15.8
9.0
14
9
G93.3
ICD-10 Finland
Postviral fatigue syndrome
15.8
9.0
14
9
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
10.2
9.0
17
17
4AA24
NOMESCO Finland
NA
37.1
9.0
11
*
1CX01
NOMESCO Finland
NA
37.1
9.0
11
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.7
9.0
60
229
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.7
9.0
61
238
A11CC03
ATC
alfacalcidol; systemic
4.7
9.0
29
63
PJA10
NOMESCO Finland
Exploration of lymph nodes
7.6
9.0
20
27
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
18.8
8.9
13
7
C83.1
ICD-10 Finland
Mantle cell lymphoma
18.8
8.9
13
7
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.3
8.9
44
139
XG405
NOMESCO Finland
Education on PEF monitoring
5.8
8.9
24
42
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
5.8
8.9
24
42
J12.1
ICD-10 Finland
Respiratory syncytial virus pneumonia
24.3
8.9
12
5
L88
ICPC
Rheumatoid/seropositive arthritis
3.2
8.9
45
145
R05CB02
ATC
bromhexine; systemic
8.1
8.9
19
24
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
2.1
8.9
99
493
4224
FHL
Endonasal anthrostomy
6.9
8.9
21
31
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
6.9
8.9
21
31
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.6
8.9
39
113
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
4.7
8.8
29
64
N03AE01
ATC
clonazepam; systemic
2.6
8.8
61
241
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
3.3
8.8
43
135
D07AC01
ATC
betamethasone; topical
1.6
8.8
276
1945
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
10.8
8.8
16
15
R60.0
ICD-10 Finland
Localized oedema
2.2
8.8
88
420
J01DC04
ATC
cefaclor; oral
5.4
8.8
25
47
M01CB01
ATC
sodium aurothiomalate; parenteral
5.4
8.8
25
47
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.3
8.8
78
352
Z94.0
ICD-10 Finland
Kidney transplant status
7.3
8.8
20
28
D07AA02
ATC
hydrocortisone; topical
1.9
8.8
137
783
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
2.7
8.7
59
230
RK110
NOMESCO Finland
NA
6.7
8.7
21
32
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.6
8.7
62
248
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
8.7
290
2076
M13.9
ICD-10 Finland
Arthritis, unspecified
2.4
8.7
72
314
R01AD11
ATC
triamcinolone; nasal
2.2
8.7
89
429
I50.0
ICD-10 Finland
Congestive heart failure
3.4
8.7
41
126
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.7
8.7
28
61
SAA03
NOMESCO Finland
Extended examination of mouth
1.6
8.7
355
2670
S01GX05
ATC
lodoxamide; ophthalmic
6.2
8.7
22
36
K07.60
ICD-10 Finland
Snapping jaw
2.7
8.6
56
213
A12AA04
ATC
calcium carbonate; oral
5.9
8.6
23
40
X58
ICD-10 Finland
Exposure to other specified factors
1.9
8.6
125
695
M25.5
ICD-10 Finland
Pain in joint
1.6
8.6
249
1718
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.7
8.6
58
225
N05BA06
ATC
lorazepam; systemic, sublingual
3.1
8.6
46
155
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
7.0
8.6
20
29
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.5
8.6
65
270
J15.8
ICD-10 Finland
Other bacterial pneumonia
10.2
8.5
16
16
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.1
8.5
45
150
W19
ICD-10 Finland
Unspecified fall
2.3
8.5
81
377
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
3.4
8.5
39
117
N03AX09
ATC
lamotrigine; oral
2.7
8.5
55
209
J06.80
ICD-10 Finland
Continuously repeating infections of a child
20.2
8.5
12
6
4931B
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA CUM EXACERBATIONE]
20.2
8.5
12
6
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
5.7
8.5
23
41
XF404
NOMESCO Finland
Ambulatory ECG
2.3
8.5
78
357
K11.2
ICD-10 Finland
Sialoadenitis
3.6
8.4
36
102
H10.4
ICD-10 Finland
Chronic conjunctivitis
6.8
8.4
20
30
49300
ICD-8 Finland
Asthma, bronchiale
4.4
8.4
29
68
R13
ICD-10 Finland
Dysphagia
2.7
8.4
57
223
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
4.2
8.3
30
73
WZA10
NOMESCO Finland
Long statement of health and health related matters
5.6
8.3
23
42
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.8
8.3
34
93
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
9.6
8.3
16
17
L50.9
ICD-10 Finland
Urticaria, unspecified
3.2
8.2
42
137
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.2
8.2
81
382
4239
FHL
Other measure in this category
14.6
8.2
13
9
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
5.5
8.2
23
43
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.0
8.2
99
514
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
8.1
98
505
M79.7
ICD-10 Finland
Fibromyalgia
3.3
8.1
39
122
Z94.2
ICD-10 Finland
Lung transplant status
33.7
8.1
10
*
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
33.7
8.1
10
*
C82.01
ICD-10 Finland
Follicular nodular lymphoma, grade I
17.4
8.1
12
7
N17.8
ICD-10 Finland
Other acute renal failure
9.0
8.1
16
18
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
9.0
8.1
16
18
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
8.0
195
1275
J20.0
ICD-10 Finland
Acute bronchitis due to Mycoplasma pneumoniae
10.1
8.0
15
15
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.2
8.0
80
380
S18
ICPC
Laceration/cut
1.5
8.0
319
2372
WX110
NOMESCO Finland
Local anesthesy
1.5
8.0
590
5032
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
2.1
8.0
93
472
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.9
8.0
122
689
R01AC01
ATC
cromoglicic acid; nasal
2.8
7.9
48
176
DHB20
NOMESCO Finland
Polypectomy of internal nose
6.7
7.9
19
29
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
2.0
7.9
106
570
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.5
7.9
63
268
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
8.6
7.8
16
19
V03AE01
ATC
polystyrene sulfonate; oral
8.6
7.8
16
19
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
10.9
7.8
14
13
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.7
7.8
180
1163
J01MA01
ATC
ofloxacin; systemic
2.3
7.7
69
313
E000001
ATC
NA
1.7
7.7
182
1179
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.5
7.7
60
253
L04AB04
ATC
adalimumab; parenteral
4.2
7.7
28
69
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.7
7.7
32
89
C82.00
ICD-10 Finland
Follicular nodular non-Hodgkin's lymphoma, ungraded
45.4
7.7
9
*
Z31.5
ICD-10 Finland
Genetic counselling
2.5
7.7
59
245
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
7.5
7.7
17
23
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
4.4
7.7
26
60
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
4.8
7.7
24
51
N05BA04
ATC
oxazepam; oral
1.7
7.6
194
1284
B03XA01
ATC
erythropoietin; parenteral
8.1
7.6
16
20
E000002
ATC
NA
1.9
7.6
110
610
R50.0
ICD-10 Finland
Fever with chills
18.5
7.6
11
6
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
12.0
7.6
13
11
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
12.0
7.6
13
11
G03.9
ICD-10 Finland
Meningitis, unspecified
25.2
7.6
10
*
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
4.4
7.6
26
61
M01AH02
ATC
rofecoxib; oral
2.0
7.6
100
536
A01
ICPC
Pain general/multiple sites
2.3
7.5
67
303
C08CA01
ATC
amlodipine; oral
1.6
7.5
225
1557
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.9
7.5
43
152
M03BX01
ATC
baclofen; systemic
4.3
7.5
26
62
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
3.3
7.4
35
108
B02.9
ICD-10 Finland
Zoster without complication
2.6
7.4
51
200
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
6.5
7.4
18
28
NF1AA
NOMESCO Finland
Hip X-ray examination
2.3
7.4
67
306
M35.2
ICD-10 Finland
Behçet disease
80.7
7.4
8
*
GD1BG
NOMESCO Finland
MRI of lungs and pleura with high intensity magnet
80.7
7.4
8
*
JN4ED
NOMESCO Finland
Body CT examination with specail preparation
80.7
7.4
8
*
ZX131
NOMESCO Finland
Intrathecal
80.7
7.4
8
*
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
5.4
7.4
21
40
212
Kela drug reimbursment
Gout
5.4
7.4
21
40
SBA00
NOMESCO Finland
Microbiological examinations
3.8
7.4
30
82
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.9
7.4
29
77
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
6.0
7.4
19
32
JMA10
NOMESCO Finland
Transabdominal total splenectomy
13.5
7.4
12
9
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
4.8
7.4
23
49
Z49.0
ICD-10 Finland
Preparatory care for dialysis
8.5
7.3
15
18
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.6
7.3
212
1454
602
Kela drug reimbursment
Children's severe malnutrition
6.9
7.3
17
25
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
5.0
7.3
22
45
C81.0
ICD-10 Finland
Nodular lymphocyte predominant Hodgkin lymphoma
+∞
7.3
7
*
D81.9
ICD-10 Finland
Combined immunodeficiency, unspecified
+∞
7.3
7
*
D81.8
ICD-10 Finland
Other combined immunodeficiencies
+∞
7.3
7
*
D89.9
ICD-10 Finland
Disorder involving the immune mechanism, unspecified
+∞
7.3
7
*
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
+∞
7.3
7
*
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.1
7.3
38
127
N06AX17
ATC
milnacipran; oral
5.9
7.2
19
33
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.6
7.2
31
89
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
15.9
7.2
11
7
G47.3
ICD-10 Finland
Sleep apnoea
1.7
7.2
164
1050
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.4
7.2
60
263
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.8
7.2
44
163
H65.0
ICD-10 Finland
Acute serous otitis media
4.5
7.2
24
55
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
4.9
7.2
22
46
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.0
7.2
87
450
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.3
7.2
62
277
ELA30
NOMESCO Finland
Biopsy of salivary gland
20.2
7.1
10
5
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
6.6
7.1
17
26
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
8.0
7.1
15
19
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.0
7.1
87
454
H20.1
ICD-10 Finland
Chronic iridocyclitis
6.1
7.1
18
30
R04.0
ICD-10 Finland
Epistaxis
2.4
7.1
56
239
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
5.7
7.1
19
34
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
5.7
7.1
19
34
WX402
NOMESCO Finland
General anaesthesia
1.7
7.1
141
868
R49.08
ICD-10 Finland
Other specified dysphonia
3.5
7.1
31
91
L03AA14
ATC
lipegfilgrastim; parenteral
4.0
7.0
26
66
G81.9
ICD-10 Finland
Hemiplegia, unspecified
7.1
7.0
16
23
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.5
7.0
55
233
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.4
7.0
58
253
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
3.5
7.0
31
92
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
2.6
7.0
48
188
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.3
7.0
33
103
D07AB08
ATC
desonide; topical
1.9
7.0
94
510
S01BC05
ATC
ketorolac; ophthalmic
3.5
7.0
30
87
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
3.1
6.9
36
120
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
5.5
6.9
19
35
RS220
NOMESCO Finland
NA
4.7
6.9
22
48
GBB00
NOMESCO Finland
Tracheostomy
7.6
6.9
15
20
A07EC02
ATC
mesalazine; oral, rectal
2.4
6.9
55
236
L82
ICD-10 Finland
Seborrhoeic keratosis
1.8
6.9
110
632
R60.9
ICD-10 Finland
Oedema, unspecified
2.8
6.9
41
149
B99
ICPC
Blood/lymph/spleen disease other
13.9
6.9
11
8
B00.2
ICD-10 Finland
Herpesviral gingivostomatitis and pharyngotonsillitis
13.9
6.9
11
8
N06AB04
ATC
citalopram; systemic
1.6
6.9
177
1174
R06.2
ICD-10 Finland
Wheezing
2.6
6.9
46
180
H25.1
ICD-10 Finland
Senile nuclear cataract
1.8
6.9
131
795
D07AB02
ATC
hydrocortisone butyrate; topical
1.6
6.8
231
1641
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
4.2
6.8
24
58
JN2AE
NOMESCO Finland
Ultrasound examination of lower part of abdomen without contrast
8.3
6.8
14
17
TEA00
NOMESCO Finland
Biopsy of lip
8.3
6.8
14
17
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
8.3
6.8
14
17
J11.1
ICD-10 Finland
Influenza with other respiratory manifestations, virus not identified
3.6
6.8
29
83
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.9
6.8
40
144
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
2.3
6.8
62
283
RK220
NOMESCO Finland
NA
11.0
6.8
12
11
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
11.0
6.8
12
11
J30.0
ICD-10 Finland
Vasomotor rhinitis
3.4
6.8
31
94
J01MA06
ATC
norfloxacin; oral
1.9
6.8
105
595
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.3
6.8
59
263
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
3.0
6.8
37
128
D73.1
ICD-10 Finland
Hypersplenism
40.4
6.8
8
*
M30.1
ICD-10 Finland
Polyarteritis with lung involvement [Churg-Strauss]
40.4
6.8
8
*
L57.0
ICD-10 Finland
Actinic keratosis
2.3
6.7
59
265
R4130
NOMESCO Finland
Speech therapy
4.2
6.7
24
59
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.3
6.7
31
95
R04
ICPC
Breathing problem other
3.2
6.7
33
106
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
3.2
6.7
33
106
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
7.2
6.7
15
21
A03FA02
ATC
cisapride; oral, rectal
2.2
6.7
64
300
JN4CD
NOMESCO Finland
Very extensive body CT
3.1
6.7
34
112
B01AA03
ATC
warfarin; systemic
1.8
6.7
108
623
2AX04
NOMESCO Finland
NA
22.7
6.7
9
*
L01AA02
ATC
chlorambucil; oral
22.7
6.7
9
*
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
2.5
6.7
48
196
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
6.5
6.7
16
25
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
7.9
6.6
14
18
R51.81
ICD-10 Finland
Facial pain NOS
3.7
6.6
27
75
R05CB01
ATC
acetylcysteine; inhalant, oral
4.7
6.6
21
46
M48.0
ICD-10 Finland
Spinal stenosis
2.0
6.6
81
422
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.9
6.6
91
497
E66.9
ICD-10 Finland
Obesity, unspecified
3.0
6.6
35
119
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
12.4
6.6
11
9
J41.1
ICD-10 Finland
Mucopurulent chronic bronchitis
12.4
6.6
11
9
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
12.4
6.6
11
9
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
8.8
6.6
13
15
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
4.8
6.6
20
42
XKD06
NOMESCO Finland
Physiologic investigation of micturition
3.5
6.5
28
81
D69.9
ICD-10 Finland
Haemorrhagic condition, unspecified
10.1
6.5
12
12
B00.10
ICD-10 Finland
Herpes simplex facialis
6.9
6.5
15
22
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
6.9
6.5
15
22
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.0
6.5
81
426
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.2
6.5
63
298
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.9
6.5
90
491
DFF00
NOMESCO Finland
Pure tone audiometry
2.1
6.5
74
375
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
2.9
6.5
38
137
J02AC02
ATC
itraconazole; systemic
1.7
6.5
148
948
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.9
6.5
92
508
C07AB02
ATC
metoprolol; systemic
1.7
6.5
126
770
XKD00
NOMESCO Finland
Uroflowmetry
1.9
6.5
92
509
J34.2
ICD-10 Finland
Deviated nasal septum
2.5
6.4
46
187
WX720
NOMESCO Finland
Own respiration
2.9
6.4
37
131
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.2
6.4
60
279
M03BC01
ATC
orphenadrine (citrate); systemic
1.6
6.4
192
1322
4940A
ICD-9 Finland
Bronchiectasis[BRONCHIECTASIAE]
70.3
6.4
7
*
B05XA03
ATC
sodium chloride; parenteral
70.3
6.4
7
*
J01XB01
ATC
colistin; inhalant, parenteral
70.3
6.4
7
*
27510
ICD-8 Finland
Plasma protein abnormalities, Hypogammaglobulinaemia
70.3
6.4
7
*
Z29.1
ICD-10 Finland
Prophylactic immunotherapy
70.3
6.4
7
*
K59.1
ICD-10 Finland
Functional diarrhoea
2.5
6.4
48
198
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.2
6.4
60
280
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
4.5
6.4
21
48
WX730
NOMESCO Finland
Conventional respirator
4.5
6.4
21
48
R09
ICPC
Sinus symptom/complaint
2.0
6.4
75
384
B81
ICPC
Anaemia vit B12/folate deficiency
3.1
6.4
32
105
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.3
6.3
54
240
RS224
NOMESCO Finland
NA
8.2
6.3
13
16
EBA10
NOMESCO Finland
Surgical removal of tooth
1.8
6.3
110
647
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
5.2
6.3
18
35
R05FB02
ATC
cough suppressants and expectorants
1.5
6.3
277
2081
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
3.6
6.3
26
73
EBA15
NOMESCO Finland
Extraction of large number of teeth
3.0
6.3
34
117
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
4.6
6.3
20
44
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
11.1
6.3
11
10
RJ420
NOMESCO Finland
NA
11.1
6.3
11
10
M81.8
ICD-10 Finland
Other osteoporosis
9.3
6.3
12
13
G72.9
ICD-10 Finland
Myopathy, unspecified
9.3
6.3
12
13
M01AG02
ATC
tolfenamic acid; oral, rectal
1.7
6.3
134
842
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.7
6.3
137
866
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.6
6.3
42
165
WW409
NOMESCO Finland
Other aferesis
18.2
6.3
9
5
J02AC03
ATC
voriconazole; systemic
18.2
6.3
9
5
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
2.6
6.3
44
176
K12.00
ICD-10 Finland
Recurrent oral aphthae
4.8
6.2
19
40
GX1K5
NOMESCO Finland
Diffusion capacity
26.9
6.2
8
*
M80.8
ICD-10 Finland
Other osteoporosis with pathological fracture
26.9
6.2
8
*
C88.0
ICD-10 Finland
Waldenström macroglobulinaemia
26.9
6.2
8
*
S29
ICPC
Skin symptom/complaint other
1.7
6.2
129
806
A99
ICPC
Disease/condition unspecnature/site
2.1
6.2
66
326
A05AA02
ATC
ursodeoxycholic acid; oral
3.8
6.2
24
64
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.7
6.2
40
152
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
6.3
6.2
15
24
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
5.4
6.2
17
32
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
5.8
6.2
16
28
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.7
6.2
38
143
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
7.7
6.1
13
17
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
3.8
6.1
24
65
K90.3
ICD-10 Finland
Pancreatic steatorrhoea
12.6
6.1
10
8
5AB14
NOMESCO Finland
NA
12.6
6.1
10
8
M35.1
ICD-10 Finland
Other overlap syndromes
12.6
6.1
10
8
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
12.6
6.1
10
8
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
12.6
6.1
10
8
L20.0
ICD-10 Finland
Besnier prurigo
2.0
6.1
71
364
ZXC20
NOMESCO Finland
Use of chemical agents
4.9
6.1
18
37
J32
ICD-10 Finland
Chronic sinusitis
8.7
6.1
12
14
DHA10
NOMESCO Finland
Biopsy of cavity of nose
8.7
6.1
12
14
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.6
6.0
41
163
R23.3
ICD-10 Finland
Spontaneous ecchymoses
4.2
6.0
21
51
N06AA10
ATC
nortriptyline; systemic
3.6
6.0
25
71
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
5.2
6.0
17
33
SXC03
NOMESCO Finland
Other oral or dental procedure
5.2
6.0
17
33
K50.8
ICD-10 Finland
Other Crohn disease
4.0
6.0
22
56
K50.0
ICD-10 Finland
Crohn disease of small intestine
4.0
6.0
22
56
R03BC01
ATC
cromoglicic acid; inhalant
3.8
6.0
23
61
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.9
6.0
81
440
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
5.6
6.0
16
29

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
672
600
35.08
307.65
12.2
2.5
8.6
10.4
g/l
16.42
662
553
284
46
87.29
307.65
2.5
2.0
12.5
9.2
%
1.06
179
23
246
48
68.59
307.65
2.6
1.9
554.8
784.9
e6/l
0.54
207
37
331
65
77.24
307.65
2.7
2.0
1.3
1.2
e9/l
0.25
239
33
276
71
54.18
307.65
2.1
1.3
1.9
2.6
g/l
3.17
229
51
287
121
33.42
307.65
2.1
1.8
0.3
0.8
g/l
3.38
232
95
275
71
53.90
307.65
2.1
1.3
4.9
7.5
g/l
3.47
230
52
201
55
45.97
307.65
2.5
1.7
749.6
739.6
e6/l
0.03
59
22
281
73
54.03
307.65
2.3
1.3
—
—
—
0
0
275
71
53.90
307.65
2.1
1.3
0.3
0.4
g/l
2.13
229
51
242
45
71.59
307.65
2.7
1.9
0.2
0.2
e9/l
0.29
207
36
263
59
61.04
307.65
2.5
1.9
36.9
44.0
%
—
21
6
562
482
26.75
307.65
4.5
1.7
1.0
1.3
g/l
2.40
509
449
162
24
81.02
302.30
2.4
1.8
546.7
307.8
e6/l
—
117
9
375
558
10.39
260.89
1.8
1.2
74.4
193.1
u/ml
1.98
300
516
632
1772
8.53
243.02
4.4
1.5
1.4
2.3
g/l
29.52
470
1084
217
174
15.83
230.12
3.1
1.2
11.4
10.6
mg/l
0.61
210
156
149
90
19.42
182.34
4.1
3.0
—
—
—
0
0
103
23
50.05
176.50
2.4
1.9
—
—
—
0
0
218
263
10.43
174.38
2.1
1.7
0.2
0.2
g/l
1.05
202
249
222
275
10.20
174.03
2.1
1.6
1.2
1.2
g/l
0.81
210
259
836
3953
9.69
162.41
20.2
5.8
0.6
0.6
e9/l
0.40
810
3423
836
3966
9.64
161.39
20.3
5.8
0.0
0.0
e9/l
1.13
809
3436
671
2624
6.19
161.10
18.8
5.8
—
—
—
0
0
839
4078
9.45
154.93
20.5
5.8
2.0
1.9
e9/l
0.12
821
3601
105
42
27.95
152.08
2.7
2.4
40.0
43.9
%
—
37
10
839
4118
9.29
151.95
21.3
6.2
0.2
0.2
e9/l
0.80
821
3624
314
689
6.29
144.59
4.1
2.6
0.2
0.2
g/l
2.73
303
652
765
3611
6.53
139.46
21.1
6.0
0.7
0.7
%
0.29
753
3378
774
3742
6.54
135.51
21.8
6.2
8.8
8.4
%
2.53
763
3519
771
3721
6.47
135.09
21.3
5.9
2.7
2.9
%
1.65
759
3482
775
3810
6.39
131.17
20.0
5.7
57.5
56.4
%
1.50
761
3582
779
3857
6.43
130.38
21.4
6.0
28.5
29.0
%
0.58
767
3618
848
4602
8.28
125.09
27.3
8.8
4.0
4.0
e9/l
0.30
824
4026
495
1800
4.62
121.04
9.6
4.1
—
—
—
0
0
344
1038
4.61
105.28
3.2
2.0
—
—
—
0
0
237
535
5.56
103.01
4.1
2.8
62.8
67.2
g/l
10.01
228
492
299
856
4.62
97.07
2.6
1.6
—
—
—
0
0
487
2024
3.86
92.98
17.4
6.3
—
—
—
0
0
168
305
6.47
91.55
3.0
1.7
—
—
—
0
0
304
918
4.38
91.44
2.4
1.4
—
—
—
0
0
201
450
5.39
87.30
4.1
2.2
—
—
—
0
0
243
638
4.76
87.23
9.2
4.5
0.9
1.0
%
0.26
108
187
302
942
4.22
86.40
3.8
2.4
21.5
23.7
%
1.60
278
820
231
587
4.87
86.28
8.4
4.3
0.6
0.6
%
0.00
87
135
315
1017
4.12
85.85
3.8
2.3
2.4
2.4
g/l
0.40
306
948
302
949
4.19
85.41
13.0
5.8
1.1
1.1
mmol/l
0.11
296
884
64
31
22.05
85.40
2.2
1.3
—
—
—
0
0
332
1117
4.02
85.28
3.8
2.3
12.4
13.7
umol/l
2.49
324
1036
630
3276
3.69
81.82
18.2
6.0
1.2
1.2
mmol/l
2.46
608
2988
627
3265
3.66
80.93
4.4
2.3
81.4
75.9
nmol/l
5.30
601
2969
664
3625
3.70
78.65
18.2
6.5
1.2
1.2
mmol/l
1.19
588
3069
224
608
4.50
76.33
9.5
4.6
0.2
0.1
%
0.19
104
171
251
753
4.16
74.69
6.5
2.8
2.0
1.8
%
2.28
237
679
589
3061
3.40
73.88
11.4
4.7
34.7
36.2
g/l
6.51
573
2875
85
90
10.27
73.19
1.9
1.6
—
—
—
0
0
85
90
10.27
73.19
1.9
1.6
—
—
—
0
0
85
90
10.27
73.19
1.9
1.6
—
—
—
0
0
85
90
10.27
73.19
1.9
1.6
—
—
—
0
0
207
545
4.57
73.15
5.1
2.6
78.3
72.7
e9/l
0.95
170
402
463
2096
3.34
72.99
9.5
3.7
7.4
7.4
ph
0.06
100
405
678
3890
3.54
71.11
12.3
6.0
9.7
11.0
umol/l
3.02
665
3684
246
764
3.99
69.29
3.4
2.0
322.2
370.5
nmol/l
2.93
229
707
209
577
4.35
69.19
9.7
4.7
0.0
0.1
%
0.59
90
143
640
3605
3.33
67.95
25.9
8.8
0.0
0.0
e9/l
0.07
576
2929
390
1661
3.27
66.90
2.2
1.9
—
—
—
0
0
312
1161
3.50
66.73
10.3
3.8
0.8
0.8
mmol/l
0.94
301
1091
84
104
8.76
64.08
2.0
1.6
—
—
—
0
0
854
5904
5.08
63.20
21.3
7.0
83.0
79.3
u/l
1.68
838
5543
127
251
5.68
62.53
3.3
2.1
1.2
2.6
ug/l
0.64
121
234
846
5841
4.81
61.91
12.9
3.9
13.0
10.9
mm/h
3.81
826
5411
91
130
7.63
61.52
1.7
1.6
—
—
—
0
0
141
312
5.13
61.10
2.0
1.4
5.8
7.6
u/ml
—
8
6
126
258
5.47
59.59
2.7
2.0
1.4
1.5
g/l
0.52
107
230
402
1851
3.02
58.68
3.5
2.2
3.3
3.0
mg/l
1.88
381
1593
83
113
7.95
58.46
5.5
3.1
1.3
1.3
%
0.00
76
93
70
77
9.73
58.43
1.8
1.2
—
—
—
0
0
293
1131
3.29
58.01
1.9
1.3
555.9
544.6
titre
0.04
58
236
284
1101
3.24
55.53
2.7
2.4
158.8
123.1
ug/g
0.79
235
877
404
1931
2.89
54.14
7.3
3.9
95.9
92.8
%
1.71
395
1882
687
4356
3.03
53.20
12.2
4.7
6.6
6.6
mmol/l
0.18
663
4028
408
1988
2.83
52.34
5.9
2.9
—
—
—
0
0
411
2021
2.81
51.66
6.0
3.0
0.2
0.4
e6/l
1.71
341
1506
108
224
5.31
50.12
3.3
3.0
—
—
—
0
0
323
1424
2.91
49.57
5.6
2.5
511.2
552.5
mosm/kgh2o
2.93
301
1228
97
185
5.72
49.35
6.8
3.6
27.0
27.9
mg/l
0.06
77
149
97
185
5.72
49.35
6.9
3.6
38.7
82.1
mg/l
0.67
76
150
188
610
3.59
48.34
15.6
7.2
10.1
8.2
mmol/l
2.91
180
584
94
179
5.71
47.87
6.9
3.6
2.5
1.8
ratio
—
7
23
83
141
6.35
47.53
6.6
3.9
—
—
—
0
0
484
2666
2.65
47.48
7.0
3.5
46.0
100.0
e6/l
1.45
376
1834
255
1007
3.09
47.47
2.0
1.5
—
—
—
0
0
89
165
5.84
46.61
1.6
1.5
—
—
—
0
0
378
1857
2.71
46.59
13.4
4.6
—
—
—
0
0
330
1519
2.79
46.15
5.4
2.4
3.9
5.9
e6/l
3.63
305
1334
107
238
4.93
45.70
5.5
2.1
7.5
10.3
g/l
7.73
92
217
266
1099
2.97
45.47
4.4
2.4
29.5
29.7
s
0.18
260
1070
422
2218
2.61
44.98
6.3
3.1
23.8
54.8
e6/l
2.15
352
1689
583
3593
2.59
44.11
5.0
2.7
173.7
108.5
ug/l
2.84
565
3344
104
233
4.88
44.01
1.3
1.2
—
—
—
0
0
57
70
8.59
43.56
1.5
1.3
0.3
0.9
u/ml
0.43
37
31
299
1358
2.75
42.37
2.0
1.6
—
—
—
0
0
361
1806
2.60
42.03
4.9
2.9
1566.2
1016.8
ng/l
0.92
332
1512
353
1771
2.57
40.59
2.9
1.9
1.4
1.1
mg/l
0.67
290
1334
213
824
3.04
40.51
2.9
1.4
—
—
—
0
0
722
5045
2.74
40.32
8.4
4.1
172.5
2479.1
e6/l
—
8
71
79
150
5.65
40.25
1.6
1.5
91.7
103.2
u/ml
0.58
23
32
93
207
4.87
39.58
5.3
2.1
39.0
38.5
g/l
0.32
87
188
220
877
2.96
39.57
4.2
3.1
6.1
7.1
umol/l
0.57
199
766
81
161
5.40
39.25
9.4
3.7
57.2
56.9
%
0.04
81
161
178
634
3.22
38.91
19.6
8.5
—
—
—
0
0
44
8
57.53
37.65
1.8
2.6
224.4
139.9
ug/g
—
34
8
356
1876
2.43
35.97
6.2
2.5
2567.2
5893.4
umol/l
1.06
331
1654
415
2359
2.34
35.06
4.6
2.2
—
—
—
0
0
390
2159
2.36
35.03
3.4
2.1
139.2
218.5
u/l
1.24
376
2036
172
638
3.07
34.85
1.6
1.4
—
—
—
0
0
142
470
3.37
34.80
1.8
1.3
—
—
—
0
0
55
84
6.89
34.77
4.0
2.5
—
—
—
0
0
735
5356
2.59
34.55
8.4
4.0
—
—
—
0
0
181
698
2.96
34.19
14.6
4.6
1.7
2.0
mmol/l
0.54
158
551
91
227
4.32
33.50
1.6
1.5
318.4
300.5
ug/g
0.33
57
139
165
613
3.04
33.25
17.2
7.5
1.3
1.3
mmol/l
0.10
155
583
41
47
9.07
32.99
1.4
1.0
—
—
—
0
0
53
83
6.70
32.71
6.4
3.6
—
—
—
0
0
154
556
3.11
32.58
5.7
4.1
84.9
78.0
ng/l
0.48
147
499
110
323
3.72
32.31
1.5
1.2
1.8
1.5
u/ml
0.10
21
21
71
151
5.00
31.79
2.7
2.4
126.9
130.1
g/l
0.25
29
115
467
2875
2.22
31.63
2.6
1.9
94.8
96.5
pmol/l
0.34
292
1456
179
721
2.82
31.00
15.9
8.8
1.0
1.3
mmol/l
0.33
142
575
448
2738
2.19
30.61
10.8
7.6
1.1
1.2
inr
0.35
130
828
178
725
2.79
30.13
15.9
8.7
11.7
12.6
kpa
1.51
166
697
178
725
2.79
30.13
15.9
8.7
5.1
5.2
kpa
0.35
166
695
104
308
3.67
30.11
1.6
1.4
—
—
—
0
0
73
172
4.51
28.85
1.6
1.4
203.8
243.3
u/ml
0.67
56
97
243
1175
2.43
28.77
2.0
1.7
1295.5
1215.2
nmol/l
0.62
205
888
161
640
2.82
28.44
17.1
9.3
95.4
95.9
%
0.58
150
621
371
2158
2.17
28.16
4.7
2.8
—
—
—
0
0
248
1221
2.39
28.13
4.1
2.7
1.2
1.1
e6/l
0.17
146
668
138
510
2.99
27.83
11.0
4.1
7.4
7.4
ph
0.39
20
54
139
516
2.98
27.81
11.1
4.0
5.0
5.1
kpa
0.56
131
484
147
564
2.90
27.70
1.7
1.4
—
—
—
0
0
36
44
8.46
27.51
1.8
1.4
4.6
8.0
u/l
1.22
31
37
99
301
3.55
27.50
4.7
3.1
21.3
21.4
s
0.05
94
272
323
1797
2.20
27.26
4.1
2.1
—
—
—
0
0
23
14
16.81
27.24
2.0
1.4
—
—
—
0
0
562
3861
2.10
27.14
7.9
4.6
0.0
0.0
estimate
0.50
133
754
300
1624
2.23
27.07
2.0
1.5
22.2
21.4
nmol/l
0.33
277
1394
31
32
9.98
26.89
2.6
2.3
61.6
103.9
ug/l
0.89
31
32
564
3895
2.09
26.66
6.2
3.4
0.0
0.0
estimate
0.50
129
724
559
3850
2.08
26.59
6.2
3.4
0.0
0.0
estimate
0.00
129
738
41
61
6.98
26.50
1.2
1.1
—
—
—
0
0
407
2499
2.09
26.41
5.0
3.2
2.3
2.4
mmol/l
4.01
367
2212
92
274
3.61
26.35
4.4
4.1
0.5
0.3
g/l
0.89
56
126
233
1151
2.35
26.00
4.3
2.8
2.7
2.9
e6/l
0.10
132
602
81
224
3.86
25.84
1.5
1.2
2.0
2.5
u/ml
0.30
16
23
81
227
3.81
25.35
1.5
1.2
12.0
9.9
u/ml
0.07
18
37
924
8028
5.14
24.44
47.0
12.1
19.0
22.2
mg/l
3.02
861
6173
42
70
6.23
24.37
4.5
3.0
61.1
53.3
%
1.19
36
47
382
2344
2.05
24.34
3.8
2.4
54.6
56.0
u/l
0.38
371
2174
113
402
3.05
24.26
11.8
6.4
—
—
—
0
0
76
211
3.83
24.09
1.3
1.2
58.9
80.0
titre
—
9
20
30
35
8.82
23.75
1.1
1.1
—
—
—
0
0
154
654
2.61
23.67
2.0
1.4
—
—
—
0
0
52
110
4.94
23.38
1.6
1.3
32.2
62.8
u/ml
—
8
6
114
417
2.97
23.28
18.9
4.8
24.3
24.2
mmol/l
0.05
100
383
54
120
4.71
22.90
1.4
1.5
—
—
—
0
0
25
24
10.67
22.75
1.4
1.4
—
—
—
0
0
186
880
2.38
22.62
1.6
1.3
—
—
—
0
0
26
27
9.87
22.41
1.6
1.4
—
—
—
0
0
305
1771
2.06
22.22
5.3
3.3
—
—
—
0
0
37
60
6.37
22.04
3.6
2.1
—
—
—
0
0
142
600
2.60
21.98
18.7
9.2
115.8
121.3
g/l
2.04
135
581
69
191
3.82
21.95
1.5
1.2
18.4
39.3
u/ml
0.64
19
17
67
182
3.88
21.89
2.3
1.4
3.6
3.7
mmol/l
0.05
62
171
42
78
5.59
21.82
2.1
1.7
—
—
—
0
0
77
232
3.52
21.62
3.5
2.1
285.4
313.8
ug/l
0.08
68
218
39
69
5.85
21.31
1.4
1.1
—
—
—
0
0
157
706
2.46
21.28
2.9
2.5
32.9
108.9
u/l
0.57
133
590
212
1088
2.22
21.16
1.3
1.2
—
—
—
0
0
18
11
16.66
21.16
2.3
3.1
—
—
—
0
0
18
11
16.66
21.16
1.3
1.9
—
—
—
0
0
405
2631
1.93
21.15
5.5
3.2
55.4
39.6
ng/l
0.29
275
1671
119
472
2.74
20.84
3.9
2.7
192.7
164.3
ng/l
0.24
102
426
34
54
6.49
20.66
3.9
3.0
—
—
—
0
0
95
337
3.02
20.42
15.7
10.4
24.3
24.4
mmol/l
0.22
86
317
38
70
5.61
19.91
1.7
1.2
—
—
—
0
0
59
157
3.94
19.83
2.5
1.6
—
—
—
0
0
72
221
3.44
19.63
1.3
1.3
—
1216.3
—
0
8
507
3601
1.87
19.61
7.2
3.8
—
—
—
0
0
38
73
5.38
19.03
3.8
3.0
—
—
—
0
0
50
122
4.27
18.87
1.1
1.1
—
—
—
0
0
18
0
+∞
18.81
1.7
0.0
—
—
—
0
0
16
11
14.78
17.65
1.3
1.1
—
—
—
0
0
233
1320
2.01
17.59
4.9
3.4
470.9
386.7
ng/l
0.10
163
936
90
337
2.84
17.52
23.7
12.3
—
—
—
0
0
60
178
3.53
17.23
2.5
1.5
59.2
198.9
e6/l
1.43
52
138
60
178
3.53
17.23
2.5
1.5
6.5
15.1
e6/l
0.61
50
135
910
8116
3.37
16.99
44.1
13.5
139.4
139.7
mmol/l
3.61
904
7897
96
384
2.67
16.46
13.7
4.1
—
—
—
0
0
125
567
2.39
16.44
2.8
2.4
4.5
15.3
au/ml
—
5
32
30
53
5.81
16.41
1.7
1.3
1888.3
1933.4
e6/l
0.02
25
35
910
8143
3.30
16.34
45.0
13.5
3.9
3.9
mmol/l
0.93
903
7907
44
110
4.14
16.09
1.5
1.1
—
—
—
0
0
249
1484
1.92
16.03
1.8
1.6
30736423.6
30208757.8
pmol/l
0.01
231
1248
114
504
2.43
15.86
3.3
3.3
4.2
4.7
pmol/l
4.56
106
443
60
190
3.30
15.57
4.1
3.6
24.5
25.0
mmol/l
0.38
55
163
49
139
3.66
15.05
1.1
1.1
—
—
—
0
0
72
261
2.90
14.86
8.3
5.2
—
—
—
0
0
239
1438
1.88
14.80
1.4
1.3
18.7
30.7
iu/ml
1.99
70
457
232
1384
1.89
14.74
1.3
1.3
4.9
11.6
u/ml
1.72
78
550
52
158
3.42
14.41
1.3
1.2
—
—
—
0
0
36
84
4.41
14.39
3.7
1.7
32.6
32.7
pg
0.03
36
84
27
49
5.64
14.36
1.6
1.3
47189.3
15462.6
e6/l
0.60
14
27
433
3132
1.70
14.08
2.6
2.0
—
—
—
0
0
17
19
9.09
13.80
1.4
1.2
—
—
—
0
0
311
2071
1.74
13.56
7.7
3.6
0.0
0.0
estimate
1.08
128
741
111
520
2.28
13.49
3.0
2.8
4.2
4.1
e9/l
0.10
81
430
26
49
5.43
13.30
1.2
1.3
—
—
—
0
0
91
393
2.45
13.28
17.2
9.1
25.2
24.8
mmol/l
0.49
83
368
20
30
6.79
12.78
1.1
1.1
1315.9
1642.6
miu/ml
0.46
20
30
78
319
2.57
12.77
1.3
1.2
—
—
—
0
0
13
11
11.97
12.65
1.1
1.5
—
—
—
0
0
24
44
5.57
12.63
1.2
1.1
—
—
—
0
0
35
89
4.04
12.54
1.2
1.4
732.8
349.6
pmol/l
0.54
29
71
72
286
2.64
12.50
1.9
1.6
10.1
9.7
u/l
0.07
60
228
17
7
24.67
12.49
2.2
1.0
—
—
—
0
0
20
31
6.57
12.40
3.3
1.8
—
—
—
0
0
305
2065
1.70
12.30
1.4
1.4
0.7
1.6
u/ml
2.55
54
543
798
6939
1.89
12.25
47.2
14.9
14.1
13.5
%
15.56
792
6800
21
35
6.11
12.16
1.8
1.1
20.4
269.7
ug/l
0.49
21
28
34
88
3.97
11.90
1.3
1.3
—
—
—
0
0
12
10
12.14
11.76
5.3
5.0
—
—
—
0
0
325
2261
1.66
11.71
4.3
3.2
7.0
7.8
mmol/l
2.33
294
1933
48
159
3.13
11.60
2.5
1.7
24719.1
15326.9
e6/l
0.32
38
117
18
27
6.78
11.49
1.9
1.6
—
—
—
0
0
17
24
7.19
11.44
2.4
1.7
—
—
—
0
0
63
245
2.68
11.41
15.2
8.8
—
—
—
0
0
111
558
2.12
11.30
7.3
3.4
—
—
—
0
0
29
70
4.24
11.13
1.2
1.1
—
—
—
0
0
22
42
5.34
11.10
1.1
1.0
—
—
—
0
0
42
133
3.26
10.94
4.9
2.7
—
—
—
0
0
34
94
3.71
10.87
2.6
2.6
—
—
—
0
0
28
68
4.21
10.67
1.3
1.2
—
—
—
0
0
44
146
3.11
10.62
6.8
3.0
—
—
—
0
0
203
1277
1.75
10.46
3.3
2.9
2.5
2.4
mmol/l
0.41
178
1127
14
18
7.88
10.16
1.1
1.1
—
—
—
0
0
26
62
4.28
10.14
1.0
1.1
—
—
—
0
0
33
94
3.60
10.12
1.3
1.2
—
—
—
0
0
920
8556
2.85
10.11
27.3
9.5
27.5
26.5
u/l
1.05
910
8284
38
119
3.28
10.09
2.1
1.6
—
—
—
0
0
160
948
1.83
10.07
1.4
1.2
—
—
—
0
0
32
90
3.64
9.99
3.6
1.8
—
—
—
0
0
25
59
4.32
9.88
1.4
1.1
—
—
—
0
0
35
106
3.39
9.79
2.0
1.5
—
—
—
0
0
37
117
3.25
9.68
1.9
1.5
—
—
—
0
0
63
266
2.46
9.67
1.5
1.2
—
—
—
0
0
12
14
8.67
9.36
1.4
1.0
—
—
—
0
0
12
14
8.67
9.36
1.4
1.0
—
—
—
0
0
12
14
8.67
9.36
1.4
1.0
—
—
—
0
0
38
125
3.12
9.33
4.3
3.2
—
—
—
0
0
21
45
4.75
9.33
1.1
1.2
—
—
—
0
0
17
30
5.75
9.30
1.5
1.1
—
—
—
0
0
128
732
1.86
8.99
1.3
1.2
—
—
—
0
0
20
43
4.73
8.85
1.7
1.3
—
—
—
0
0
132
766
1.84
8.84
21.7
20.0
1.3
1.2
inr
—
8
118
723
6303
1.60
8.75
5.4
4.0
14.9
14.6
pmol/l
2.25
687
5800
279
1993
1.56
8.51
4.5
3.2
1540.6
226.7
mg/l
1.85
180
1260
44
166
2.73
8.49
1.2
1.1
—
—
—
0
0
33
106
3.19
8.44
1.1
1.4
—
—
—
0
0
40
144
2.86
8.42
1.4
1.2
—
—
—
0
0
32
102
3.21
8.29
1.1
1.3
—
—
nmol/l
—
0
0
10
11
9.18
8.10
1.2
2.5
—
—
—
0
0
43
165
2.68
8.04
1.2
1.1
—
—
—
0
0
12
17
7.14
8.01
2.7
1.9
—
—
—
0
0
44
174
2.60
7.76
7.3
3.0
7.4
7.4
ph
0.17
39
145
13
21
6.26
7.72
1.1
1.1
—
—
—
0
0
13
21
6.26
7.72
1.1
1.1
—
—
—
0
0
13
21
6.26
7.72
1.1
1.1
—
—
—
0
0
907
8498
2.24
7.69
33.2
11.3
—
—
—
0
0
11
6
18.52
7.61
1.1
1.2
—
—
—
0
0
39
148
2.70
7.47
7.3
3.1
2.2
2.7
mmol/l
0.62
29
99
21
54
3.95
7.46
2.0
1.4
—
—
—
0
0
20
52
3.91
7.01
2.0
1.6
—
—
—
0
0
36
136
2.71
6.96
5.7
2.6
16.6
16.5
%
0.08
24
72
621
5351
1.46
6.94
4.6
3.4
—
—
—
0
0
25
77
3.31
6.87
2.0
1.6
61.2
57.3
%
0.19
18
60
281
2090
1.49
6.87
5.3
3.9
29.0
9.1
mg/mmol
2.30
187
1316
67
338
2.06
6.78
2.7
2.3
—
—
—
0
0
30
106
2.89
6.57
1.4
1.1
—
—
—
0
0
809
7405
1.59
6.33
6.3
4.7
1.9
2.2
mu/l
0.68
781
6853
29
103
2.87
6.30
2.4
3.2
24.9
22.9
nmol/l
0.30
29
97
25
82
3.10
6.23
2.7
4.5
53.6
94.9
u/ml
—
7
25
286
2170
1.45
6.21
6.2
3.0
—
—
—
0
0
11
19
5.85
6.11
5.6
3.5
—
—
—
0
0
53
259
2.11
5.85
19.5
7.3
1.6
1.6
%
0.19
48
244
11
20
5.55
5.81
1.0
1.0
—
—
—
0
0
33
132
2.55
5.75
1.8
1.1
62.5
3541.9
iu/ml
0.50
12
36
231
3028
0.69
5.69
3.2
2.6
—
—
—
0
0
85
495
1.79
5.63
1.9
1.5
21.1
25.9
iu/l
0.77
75
417
230
1707
1.46
5.53
6.3
3.6
1.0
1.0
kg/l
0.29
20
227
37
160
2.37
5.48
30.5
4.1
—
—
—
0
0
31
124
2.55
5.41
1.8
1.3
—
—
—
0
0
12
26
4.66
5.27
2.4
2.7
—
—
—
0
0
18
54
3.38
5.18
3.8
2.2
—
—
—
0
0
43
204
2.16
5.15
23.8
8.8
1.6
1.2
mmol/l
0.97
37
177
15
40
3.79
5.10
1.6
1.7
—
—
—
0
0
10
19
5.31
5.05
1.1
1.1
—
—
—
0
0
9
9
10.08
5.03
3.8
1.4
40.2
38.0
umol/l
—
9
9
14
36
3.93
5.00
1.2
1.2
—
—
—
0
0
86
526
1.70
4.82
2.9
2.3
13.7
12.8
nmol/l
0.42
73
472
58
315
1.90
4.82
2.5
1.7
—
—
—
0
0
15
42
3.61
4.78
1.2
1.3
121.8
152.5
nmol/l
1.06
15
42
134
916
1.54
4.78
1.7
1.7
—
—
—
0
0
105
680
1.61
4.72
3.2
4.1
18.6
25.5
ug/l
0.14
80
550
20
69
2.94
4.62
1.4
1.2
—
—
—
0
0
54
937
0.55
4.44
1.3
1.3
—
—
—
0
0
23
89
2.62
4.33
2.3
2.3
—
—
—
0
0
10
22
4.58
4.31
2.8
1.8
—
—
—
0
0
12
31
3.91
4.26
4.8
1.8
—
—
—
0
0
55
308
1.83
4.19
1.3
1.3
241.2
246.2
miu/ml
0.03
21
152
30
134
2.28
4.19
1.2
1.2
5.9
5.3
u/ml
—
10
55
104
693
1.56
4.16
9.3
3.4
—
—
—
0
0
9
14
6.48
3.99
1.3
1.0
6.2
5.6
mg/g
—
9
14
9
14
6.48
3.99
1.1
1.1
—
—
—
0
0
11
28
3.96
3.98
2.9
2.4
—
—
—
0
0
9
15
6.05
3.82
1.3
1.0
—
—
—
0
0
12
34
3.56
3.77
1.0
1.1
—
—
—
0
0
38
195
1.99
3.77
1.1
1.1
6.9
7.1
u/ml
0.02
29
116
8
12
6.71
3.68
2.0
1.4
—
—
—
0
0
47
263
1.83
3.62
3.3
2.9
162.6
1297.4
u/ml
0.97
42
222
7
9
7.82
3.56
1.9
3.1
—
—
—
0
0
34
172
2.01
3.52
1.4
1.3
—
—
—
0
0
58
349
1.70
3.51
1.1
1.1
—
—
—
0
0
6
6
10.05
3.50
11.0
5.5
4.5
6.9
mmol/l
—
6
6
95
647
1.52
3.47
1.6
1.2
57.9
157.5
iu/ml
4.65
45
259
30
574
0.51
3.43
1.5
1.4
—
—
—
0
0
17
64
2.69
3.41
1.9
1.4
193562.1
150033.0
e6/l
0.08
12
45
98
675
1.50
3.40
9.8
3.8
—
—
—
0
0
82
544
1.55
3.37
2.5
2.2
5.4
6.6
ug/l
0.51
73
483
11
32
3.47
3.34
1.2
1.2
—
—
—
0
0
257
2094
1.31
3.30
1.6
1.7
1.5
1.4
mmol/l
0.59
235
1789
23
103
2.26
3.24
2.3
1.4
—
—
—
0
0
9
19
4.77
3.24
1.6
1.1
—
—
—
0
0
8
15
5.37
3.19
1.9
3.3
19.9
20.6
mmol/l
—
8
15
35
188
1.89
3.09
1.1
1.1
0.3
0.7
u/ml
1.53
22
98
27
133
2.06
3.03
2.1
1.8
—
—
—
0
0
34
187
1.85
2.82
1.2
1.2
—
—
—
0
0
7
14
5.03
2.73
1.3
1.1
—
—
—
0
0
6
10
6.03
2.70
3.2
3.0
—
—
—
0
0
34
190
1.82
2.69
2.5
2.8
—
—
—
0
0
8
19
4.24
2.68
8.1
8.2
—
—
—
0
0
15
61
2.48
2.63
22.4
5.3
10.7
11.4
%
0.29
15
61
7
15
4.69
2.60
5.9
2.1
—
—
—
0
0
33
186
1.80
2.56
1.2
1.1
4.7
4.0
u/ml
0.06
13
44
6
11
5.48
2.54
1.0
1.1
—
—
—
0
0
6
11
5.48
2.54
1.0
1.1
—
—
—
0
0
77
540
1.46
2.49
1.2
1.2
—
—
—
0
0
57
376
1.55
2.46
2.4
2.3
7866.9
3434.6
u/l
0.35
18
157
37
219
1.72
2.44
1.2
1.1
0.8
2.4
u/ml
1.46
23
107
930
9096
1.74
2.31
59.4
17.9
248.4
256.1
e9/l
2.22
924
8867
10
35
2.88
2.31
1.3
1.5
—
—
—
0
0
13
53
2.47
2.28
1.8
1.5
28.6
34.5
%
—
8
38
27
149
1.84
2.26
1.9
1.5
0.2
0.4
nmol/l
1.76
21
119
930
9100
1.73
2.25
59.4
17.9
4.4
4.5
e12/l
10.60
919
8854
930
9102
1.72
2.22
59.5
17.9
7.2
6.6
e9/l
3.26
920
8851
57
386
1.51
2.21
1.1
1.1
—
—
—
0
0
239
2026
1.24
2.14
5.2
3.5
—
—
—
0
0
47
310
1.54
2.07
2.2
2.3
—
—
—
0
0
6
15
4.02
2.04
3.3
1.2
3.2
2.6
mmol/l
—
6
15
41
264
1.58
2.01
3.3
3.1
—
—
—
0
0
132
1051
1.30
1.99
1.7
1.5
—
—
—
0
0
47
314
1.52
1.97
1.6
1.6
—
—
—
0
0
14
64
2.21
1.95
1.0
1.0
—
—
—
0
0
15
73
2.07
1.81
1.1
1.2
1.8
1.4
nmol/l
0.41
15
67
8
29
2.77
1.79
1.3
1.2
—
—
—
0
0
22
127
1.75
1.65
1.1
1.1
1.6
6.2
u/ml
1.70
11
50
34
222
1.55
1.61
2.3
1.7
43.1
38.3
nmol/l
0.58
34
217
14
70
2.01
1.59
1.1
1.5
—
—
—
0
0
5
15
3.34
1.52
10.2
9.7
—
—
—
0
0
0
45
0.00
1.50
0.0
1.2
—
—
—
0
0
7
28
2.51
1.45
1.9
2.2
—
—
—
0
0
21
125
1.70
1.44
1.2
1.2
—
—
—
0
0
15
81
1.87
1.40
3.8
2.4
—
—
—
0
0
24
150
1.62
1.39
3.6
2.0
—
—
—
0
0
51
376
1.38
1.35
2.1
2.2
—
—
—
0
0
45
325
1.40
1.34
5.3
3.3
—
—
—
0
0
11
54
2.05
1.33
1.6
1.4
—
—
—
0
0
5
18
2.79
1.28
2.2
1.7
—
—
—
0
0
22
139
1.60
1.24
1.1
1.1
—
—
—
0
0
54
409
1.34
1.23
2.1
2.2
—
—
—
0
0
5
19
2.64
1.21
1.2
1.2
—
—
—
0
0
54
410
1.34
1.21
2.1
2.2
—
—
—
0
0
54
411
1.33
1.19
2.1
2.1
—
—
—
0
0
19
117
1.64
1.18
1.0
1.1
0.1
1.5
u/ml
—
8
30
77
950
0.79
1.16
1.9
1.8
—
—
—
0
0
22
143
1.55
1.12
1.1
1.0
10.3
4.8
u/ml
0.33
13
52
786
7625
1.17
1.10
41.8
13.0
39.3
40.1
%
2.72
615
5856
53
408
1.32
1.10
1.7
2.0
—
—
—
0
0
31
220
1.42
1.06
2.1
1.9
3.1
4.9
iu/l
1.12
11
74
5
22
2.28
1.03
2.6
3.6
—
—
—
0
0
14
85
1.66
0.94
1.4
1.1
—
—
—
0
0
6
31
1.94
0.84
2.0
2.6
9.2
10.2
mg/l
—
6
26
6
33
1.82
0.79
2.8
3.2
23.6
31.1
umol/l
—
6
24
22
157
1.41
0.77
3.7
3.8
27.6
25.5
mg/l
0.11
14
98
6
34
1.77
0.76
1.5
4.1
—
—
—
0
0
57
469
1.23
0.75
4.2
2.6
—
—
—
0
0
735
7155
1.12
0.75
6.5
5.2
39.4
39.1
mmol/mol
0.38
699
6702
7
41
1.71
0.70
1.6
1.1
127.2
177.7
iu/ml
—
7
41
7
42
1.67
0.68
5.1
7.9
—
—
—
0
0
5
28
1.79
0.66
1.2
1.3
—
—
—
0
0
771
7861
0.90
0.61
4.8
4.2
4.6
4.8
mmol/l
2.39
739
7353
42
508
0.82
0.60
2.5
1.7
—
—
—
0
0
10
64
1.57
0.58
1.4
1.1
328.4
402.6
nmol/l
—
10
58
740
7554
0.91
0.58
4.5
3.7
1.4
1.3
mmol/l
4.64
705
7001
768
7826
0.91
0.58
4.7
4.1
1.5
1.5
mmol/l
1.25
730
7286
16
218
0.73
0.56
1.4
1.3
—
—
—
0
0
242
2269
1.09
0.53
1.6
1.5
—
—
—
0
0
10
67
1.50
0.49
1.7
1.6
0.9
1.1
g/l
—
10
67
8
120
0.66
0.45
1.1
1.6
—
—
—
0
0
787
7985
0.92
0.43
5.2
4.6
2.7
2.8
mmol/l
3.67
745
7423
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
5
37
1.35
0.37
1.2
1.2
—
—
—
0
0
17
137
1.25
0.32
4.9
5.3
352.2
364.0
umol/l
0.12
17
124
774
7644
1.07
0.31
5.0
4.1
5.9
5.8
mmol/l
0.73
741
7031
17
208
0.81
0.31
1.4
1.5
—
—
—
0
0
104
973
1.08
0.27
3.0
2.8
0.6
0.7
ug/l
0.51
78
587
17
202
0.84
0.25
1.4
1.4
—
—
—
0
0
20
170
1.18
0.24
6.5
4.3
—
—
—
0
0
17
201
0.84
0.24
1.4
1.4
—
—
—
0
0
5
39
1.28
0.23
1.0
1.0
—
—
—
0
0
11
88
1.25
0.22
2.4
2.2
—
—
—
0
0
20
172
1.17
0.22
3.2
2.4
257.9
94.9
ug/min
0.62
15
108
25
221
1.13
0.20
2.4
2.5
—
—
—
0
0
11
91
1.21
0.17
4.4
2.9
0.7
0.9
nmol/l
—
6
71
5
68
0.73
0.17
3.8
2.5
—
—
—
0
0
171
1655
1.04
0.16
4.1
4.4
1.7
2.4
ug/l
1.37
164
1502
8
96
0.83
0.13
1.8
1.1
—
—
—
0
0
21
194
1.08
0.09
1.1
1.1
—
—
—
0
0
6
64
0.94
0.00
1.5
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
8.8
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
190.4
—
0
5

Mortality – FinRegistry

Association

Association between endpoint D3_IMMUDEFANTIBODY and mortality.

Females

Parameter HR [95% CI] p-value
D3_IMMUDEFANTIBODY 2.903 [2.37, 3.55] < 0.001
Birth year 0.996 [0.99, 1.0] 0.301

During the follow-up period (1.1.1998 — 31.12.2019), 305 out of 2102 females with D3_IMMUDEFANTIBODY died.

Males

Parameter HR [95% CI] p-value
D3_IMMUDEFANTIBODY 2.794 [2.15, 3.63] < 0.001
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 231 out of 1401 males with D3_IMMUDEFANTIBODY died.

Mortality risk

Mortality risk for people of age

years, who have D3_IMMUDEFANTIBODY.

N-year risk Females Males
1 0.329% 0.461%
5 1.814% 2.947%
10 4.576% 7.651%
15 8.876% 13.489%
20 14.553% 22.313%

Relationships between endpoints

Index endpoint: D3_IMMUDEFANTIBODY – Immunodeficiency with predominantly antibody defects

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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