Selective deficiency of immunoglobulin G [IgG] subclasses

D3_DEF_IGG

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D80.3
  • Cause of death: ICD-10 D80.3

2 out of 7 registries used, show all original rules.

249

4. Check minimum number of events

None

249

5. Include endpoints

None

249

6. Filter based on genotype QC (FinnGen only)

249

Control definitions (FinnGen only)

Control exclude
D3_IMMUNEMECHANISM

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D80
Name in latin
Deficientia selectiva subclassium immunoglobulini G

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1014 665 344
Only index persons 956 637 319
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.01
Only index persons 0.02 0.02 0.01
Median age at first event (years)
Whole population 43.56 45.95 38.66
Only index persons 44.64 46.75 40.42

-FinnGen-

Key figures

All Female Male
Number of individuals 249 184 65
Unadjusted period prevalence (%) 0.05 0.06 0.03
Median age at first event (years) 47.90 47.95 47.76

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
222
Matched controls
2219
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
+∞
321.5
222
*
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
+∞
81.4
73
*
120
Kela drug reimbursment
Hypogammaglobulinaemia
+∞
67.2
61
*
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
+∞
63.7
58
*
J01MA12
ATC
levofloxacin; systemic
11.0
50.9
116
201
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
603.8
50.5
48
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
25.4
50.3
72
41
H02AB06
ATC
prednisolone; systemic
10.6
49.5
186
729
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
+∞
48.8
45
*
R03DC03
ATC
montelukast; oral
8.8
41.8
107
211
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
24.5
41.8
60
33
J45.9
ICD-10 Finland
Asthma, unspecified
8.7
41.5
108
218
J01MA14
ATC
moxifloxacin; systemic
13.2
41.4
78
87
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.8
38.5
159
598
J45.1
ICD-10 Finland
Nonallergic asthma
14.6
38.4
68
65
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
16.8
37.5
62
50
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
10.5
34.9
74
101
J45.0
ICD-10 Finland
Predominantly allergic asthma
10.6
34.7
73
98
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
24.5
33.1
47
24
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
7.0
33.0
98
225
WW200
NOMESCO Finland
Immunization
27.1
32.0
44
20
TPH04
NOMESCO Finland
Cathetrisation of vein
6.5
31.8
102
257
ZX120
NOMESCO Finland
Intravenous
9.5
31.7
71
105
R50.9
ICD-10 Finland
Fever, unspecified
7.6
31.2
83
161
D80.0
ICD-10 Finland
Hereditary hypogammaglobulinaemia
+∞
29.9
28
*
H02AB07
ATC
prednisone; oral
6.9
27.9
79
164
J18.9
ICD-10 Finland
Pneumonia, unspecified
6.0
27.7
91
229
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
10.7
27.2
55
66
TDM10
NOMESCO Finland
Puncture of maxillary antrum
11.6
26.0
50
54
R03AK06
ATC
salmeterol and fluticasone; inhalant
6.6
24.7
71
147
J01FF01
ATC
clindamycin; systemic
4.8
24.7
109
372
6BA02
NOMESCO Finland
NA
+∞
24.4
23
*
J47
ICD-10 Finland
Bronchiectasis
27.4
24.3
33
14
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
5.6
23.9
81
206
J01.0
ICD-10 Finland
Acute maxillary sinusitis
4.6
23.7
107
370
J01MA02
ATC
ciprofloxacin; systemic
4.4
23.6
131
551
R03BB04
ATC
tiotropium bromide; inhalant
8.9
23.1
52
74
J01FA06
ATC
roxithromycin; oral
4.2
22.6
140
643
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
8.6
22.4
51
74
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
4.4
21.9
169
934
R03AC02
ATC
salbutamol; inhalant
4.3
21.8
164
885
R03BA02
ATC
budesonide; inhalant
5.0
21.7
83
238
J01FA15
ATC
telithromycin; oral
6.3
21.4
63
132
D80.2
ICD-10 Finland
Selective deficiency of immunoglobulin A [IgA]
+∞
21.2
20
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
4.0
20.9
152
782
UDH02
NOMESCO Finland
Rhinopharyngoscopy
8.6
20.8
47
67
R03BA05
ATC
fluticasone; inhalant
4.7
20.7
83
248
R03AC12
ATC
salmeterol; inhalant
14.7
20.2
34
27
D84.18
ICD-10 Finland
Other specified defect in the complement system
+∞
20.1
19
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.4
19.4
65
158
J01FA09
ATC
clarithromycin; systemic
3.8
19.4
120
526
XG474
NOMESCO Finland
Exhalation nntrogen oxide
15.5
18.9
31
23
R03AK08
ATC
formoterol and beclometasone; inhalant
13.2
18.7
33
29
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
12.3
18.7
34
32
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.6
18.6
51
96
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
7.9
18.6
44
67
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.8
18.4
106
432
R03AC13
ATC
formoterol; inhalant
14.2
18.3
31
25
R03AK07
ATC
formoterol and budesonide; inhalant
4.3
18.0
79
252
H02AB04
ATC
methylprednisolone; systemic
4.8
17.8
67
183
Z01.8
ICD-10 Finland
Other specified special examinations
4.1
17.8
84
287
C01CA24
ATC
epinephrine; parenteral
6.4
17.2
48
92
R01AD08
ATC
fluticasone; nasal
3.6
17.2
108
465
J01FA10
ATC
azithromycin; systemic
3.9
16.8
178
1136
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
183.2
16.7
17
*
J45.8
ICD-10 Finland
Mixed asthma
13.2
16.6
29
25
R06.0
ICD-10 Finland
Dyspnoea
3.8
16.4
85
311
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.7
16.3
92
360
H02AB09
ATC
hydrocortisone; systemic
12.7
16.3
29
26
R03DA04
ATC
theophylline; systemic, rectal
11.1
16.3
31
32
R03BB01
ATC
ipratropium bromide; inhalant
17.4
16.1
25
16
XG410
NOMESCO Finland
Flow-volume spirometry
12.2
16.0
29
27
J32.4
ICD-10 Finland
Chronic pansinusitis
19.0
16.0
24
14
TGC00
NOMESCO Finland
Bronchial lavation
15.3
16.0
26
19
D83.9
ICD-10 Finland
Common variable immunodeficiency, unspecified
+∞
15.8
15
*
D83.0
ICD-10 Finland
Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
+∞
15.8
15
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
8.1
15.7
36
52
R01AD05
ATC
budesonide; nasal
5.9
15.4
45
91
TAB00
NOMESCO Finland
Lumbar puncture
8.8
15.3
33
43
A41.9
ICD-10 Finland
Sepsis, unspecified
16.7
15.3
24
16
J01AA02
ATC
doxycycline; systemic
4.6
15.2
198
1429
N03AX12
ATC
gabapentin; oral
4.4
15.1
61
176
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
5.6
15.0
46
99
C03CA01
ATC
furosemide; systemic
3.9
15.0
71
238
N02AA05
ATC
oxycodone; systemic
5.1
14.8
50
120
M05BA04
ATC
alendronic acid; oral
7.6
14.8
35
53
R01AD09
ATC
mometasone; nasal
3.1
14.7
143
813
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
24.3
14.5
20
9
N03AX16
ATC
pregabalin; oral
3.5
14.5
83
323
J45
ICD-10 Finland
Asthma
5.4
14.2
45
100
UJF30
NOMESCO Finland
Ileoscopy through colon
5.1
14.1
47
111
XQ800
NOMESCO Finland
Prick test
5.1
14.1
47
111
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
16.1
13.9
22
15
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
4.2
13.9
58
172
H04.10
ICD-10 Finland
Dry eye syndrome
5.1
13.8
46
108
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
80.2
13.8
15
*
D84.9
ICD-10 Finland
Immunodeficiency, unspecified
+∞
13.7
13
*
R03BA08
ATC
ciclesonide; inhalant
5.5
13.5
41
87
J46
ICD-10 Finland
Status asthmaticus
12.7
13.2
23
20
N06AX21
ATC
duloxetine; oral
4.5
13.0
50
136
R01AD12
ATC
fluticasone furoate; nasal
3.0
13.0
101
481
R03BA01
ATC
beclometasone; inhalant
4.1
13.0
56
170
J02AC01
ATC
fluconazole; systemic
2.9
13.0
127
699
J01DB01
ATC
cefalexin; oral
4.5
12.8
203
1558
N02AX02
ATC
tramadol; systemic, rectal
2.9
12.6
115
604
GD1DG
NOMESCO Finland
Extremely extensive MRI examination of pleura with high field magnet
+∞
12.6
12
*
A02BC05
ATC
esomeprazole; systemic
2.9
12.6
115
606
J05AB11
ATC
valaciclovir; oral
3.9
12.5
56
176
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
7.2
12.4
30
47
A07AA02
ATC
nystatin; oral
5.4
12.3
38
82
R03AC03
ATC
terbutaline; inhalant
3.8
12.1
57
186
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.3
12.1
47
129
J01DA01
ATC
[U] cefalexin; systemic
2.9
12.0
161
1058
J20
ICD-10 Finland
Acute bronchitis
4.6
12.0
43
109
N05BA01
ATC
diazepam; systemic, rectal
4.1
12.0
50
147
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
6.3
11.9
32
58
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.8
11.9
110
577
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
17.7
11.9
18
11
XW000
NOMESCO Finland
Bone marrow biopsy
8.3
11.8
26
35
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.1
11.7
49
144
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
14.7
11.7
19
14
J31.0
ICD-10 Finland
Chronic rhinitis
4.6
11.6
42
107
R01BA52
ATC
pseudoephedrine, combinations; oral
2.8
11.6
100
499
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.5
11.6
62
223
D80.6
ICD-10 Finland
Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
+∞
11.6
11
*
M79.0
ICD-10 Finland
Rheumatism, unspecified
7.6
11.3
26
38
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.7
11.2
39
96
A03FA01
ATC
metoclopramide; systemic, rectal
3.0
11.1
76
325
E0000UV
ATC
NA
2.7
11.1
112
609
N05CF01
ATC
zopiclone; oral
2.8
11.0
89
425
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
11.0
83
380
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.8
10.9
94
464
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
29.7
10.9
14
5
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.7
10.8
31
61
J32.1
ICD-10 Finland
Chronic frontal sinusitis
63.1
10.7
12
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.8
10.6
36
86
J01DA06
ATC
[U] cefuroxime; systemic
3.5
10.5
54
188
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
4.0
10.5
44
129
P01AB01
ATC
metronidazole; oral, rectal
2.6
10.5
115
648
WE300
NOMESCO Finland
Profylactive therapy of malignancy with biomoidiers
+∞
10.5
10
*
X59
ICD-10 Finland
Exposure to unspecified factor
3.2
10.4
61
235
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.3
10.3
39
104
N03AX11
ATC
topiramate; oral
9.9
10.3
20
22
WZC30
NOMESCO Finland
Teaching
3.6
10.2
49
161
R03DC01
ATC
zafirlukast; oral
15.6
10.2
16
11
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
6.0
9.9
27
50
R53
ICD-10 Finland
Malaise and fatigue
3.1
9.9
61
241
TPX10
NOMESCO Finland
Implantation of vascular injection port
12.2
9.7
17
15
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.7
9.7
80
380
S01GX01
ATC
cromoglicic acid; ophthalmic
2.8
9.5
70
309
GD1CG
NOMESCO Finland
Extensive examination of lungs and pleura with high intensity magnet
104.3
9.5
10
*
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
104.3
9.5
10
*
3XA02
NOMESCO Finland
NA
+∞
9.4
9
*
M36.8*D80.1
ICD-10 Finland
Systemic disorders of connective tissue in hypogammaglobulinaemia
+∞
9.4
9
*
XF400
NOMESCO Finland
ECG with 12 standard connections
3.4
9.4
50
175
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.0
9.4
38
108
JN4BD
NOMESCO Finland
Extensive body CT
3.9
9.2
39
115
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
9.7
9.2
18
20
R52.9
ICD-10 Finland
Pain, unspecified
4.2
9.2
35
94
N06AX11
ATC
mirtazapine; oral
2.6
9.2
89
461
WX002
NOMESCO Finland
Sedation and analgesia
3.0
9.1
60
245
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
7.4
9.1
21
31
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
6.1
9.1
24
43
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
19.6
9.0
13
7
H65.2
ICD-10 Finland
Chronic serous otitis media
25.2
9.0
12
5
L04AX01
ATC
azathioprine; systemic
7.1
8.9
21
32
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.0
8.9
24
44
R06AX22
ATC
ebastine; oral
2.9
8.9
59
243
XG466
NOMESCO Finland
Sleep oxymetry
8.2
8.9
19
25
G72.9
ICD-10 Finland
Myopathy, unspecified
52.1
8.7
10
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.9
8.7
36
104
A02BC02
ATC
pantoprazole; systemic
2.4
8.6
154
1075
R51.80
ICD-10 Finland
Headache
3.1
8.6
52
202
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
6.0
8.6
23
42
A07AA09
ATC
vancomycin; oral
21.0
8.6
12
6
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
21.0
8.6
12
6
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
93.5
8.5
9
*
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
93.5
8.5
9
*
ZX112
NOMESCO Finland
Subcutaneous
7.6
8.5
19
27
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.5
8.4
41
136
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
10.0
8.4
16
17
R06AE09
ATC
levocetirizine; oral
2.9
8.4
57
238
R01AD11
ATC
triamcinolone; nasal
3.9
8.4
35
102
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.4
8.4
101
580
D83.8
ICD-10 Finland
Other common variable immunodeficiencies
+∞
8.4
8
*
H65.3
ICD-10 Finland
Chronic mucoid otitis media
8.7
8.3
17
21
P01BA02
ATC
hydroxychloroquine; oral
4.0
8.2
33
93
ZXA10
NOMESCO Finland
Bilateral
2.8
8.2
56
235
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
3.8
8.1
35
105
R05
ICD-10 Finland
Cough
2.8
8.1
58
250
R06AE07
ATC
cetirizine; oral
2.3
8.1
122
773
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
6.6
8.1
20
33
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.1
8.0
48
184
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
3.6
8.0
37
118
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
9.0
8.0
16
19
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
7.4
8.0
18
26
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
5.7
7.9
22
42
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.3
7.9
95
538
J01.1
ICD-10 Finland
Acute frontal sinusitis
11.4
7.9
14
13
M35.7
ICD-10 Finland
Hypermobility syndrome
11.4
7.9
14
13
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
6.0
7.9
21
38
J01.9
ICD-10 Finland
Acute sinusitis, unspecified
6.8
7.9
19
30
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.2
7.9
43
154
ZXA00
NOMESCO Finland
Right side
2.6
7.9
68
324
R13
ICD-10 Finland
Dysphagia
4.7
7.8
26
61
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.4
7.8
39
132
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
5.6
7.8
22
43
A02BC01
ATC
omeprazole; systemic
2.5
7.8
70
343
M79.7
ICD-10 Finland
Fibromyalgia
7.2
7.8
18
27
C07AB07
ATC
bisoprolol; oral
2.3
7.7
100
586
UKC02
NOMESCO Finland
Cystoscopy
3.4
7.7
38
127
J11.1
ICD-10 Finland
Influenza with other respiratory manifestations, virus not identified
12.5
7.7
13
11
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
19.2
7.7
11
6
UDM02
NOMESCO Finland
Sinoscopy
8.1
7.5
16
21
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
4.3
7.5
27
69
B29
ICPC
Lymph/immune mech sympt/complt other
82.7
7.5
8
*
ZX110
NOMESCO Finland
Intracutaneous
82.7
7.5
8
*
UJF32
NOMESCO Finland
Coloscopy
2.5
7.5
64
305
WW500
NOMESCO Finland
Blood transfusion
5.8
7.4
20
37
D07AA02
ATC
hydrocortisone; topical
3.1
7.3
42
157
DMB10
NOMESCO Finland
Radical maxillary antrotomy
16.4
7.3
11
7
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
16.4
7.3
11
7
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.6
7.3
32
98
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
7.0
7.3
17
26
GD1AD
NOMESCO Finland
Thorax CT examination
6.4
7.2
18
30
J01.4
ICD-10 Finland
Acute pansinusitis
31.1
7.2
9
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.1
7.2
27
72
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
9.3
7.2
14
16
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.9
7.1
47
191
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.1
7.1
40
147
SPAT1262
SPAT
Handing over of treatment supplies
2.8
7.1
47
192
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
6.7
7.1
17
27
A06AD11
ATC
lactulose; oral
3.3
7.1
36
124
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.6
7.1
57
261
A01AB09
ATC
miconazole; local oral
3.6
7.1
31
95
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
2.4
7.0
66
329
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.5
7.0
32
101
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
3.1
7.0
39
143
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
7.1
7.0
16
24
L04AA13
ATC
leflunomide; oral
6.5
6.9
17
28
M05BB03
ATC
alendronic acid and colecalciferol; oral
9.8
6.9
13
14
J05AB01
ATC
aciclovir; systemic
2.4
6.9
63
310
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.5
6.9
32
103
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.2
6.8
25
65
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.2
6.8
25
65
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
7.6
6.8
15
21
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.8
6.8
28
81
ZX114
NOMESCO Finland
Intramuscular
17.4
6.8
10
6
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
17.4
6.8
10
6
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
41.4
6.8
8
*
J32.2
ICD-10 Finland
Chronic ethmoidal sinusitis
41.4
6.8
8
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
3.7
6.8
29
87
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
4.5
6.7
23
56
ZX121
NOMESCO Finland
Central venous catheter
23.3
6.7
9
*
JN3AD
NOMESCO Finland
Abdominal CT examination
3.9
6.7
27
77
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.3
6.7
33
111
N02BE01
ATC
paracetamol; systemic, rectal
2.6
6.7
193
1589
ND1AA
NOMESCO Finland
Wrist X-ray examination
4.0
6.7
26
72
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.7
6.6
21
48
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.3
6.5
32
107
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
5.2
6.5
19
39
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
7.8
6.5
14
19
A02BC03
ATC
lansoprazole; oral
2.3
6.5
70
371
A01AB04
ATC
amphotericin B; local oral
5.5
6.5
18
35
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
14.9
6.5
10
7
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
6.3
6.4
16
27
N06AA09
ATC
amitriptyline; systemic
3.2
6.4
33
115
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.1
6.3
35
126
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.6
6.3
48
212
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
5.7
6.3
17
32
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.7
6.3
26
76
M81.4
ICD-10 Finland
Drug-induced osteoporosis
+∞
6.3
6
*
2790C
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[DEFICIENTIA IMMUNOGLOBULINI ALIA]
+∞
6.3
6
*
DPA20
NOMESCO Finland
Trephine of frontal sinus
+∞
6.3
6
*
K59.0
ICD-10 Finland
Constipation
5.0
6.3
19
41
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
27.5
6.3
8
*
R01BA51
ATC
phenylpropanolamine, combinations; oral
2.7
6.2
45
193
R51.81
ICD-10 Finland
Facial pain NOS
8.0
6.2
13
17
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
8.0
6.2
13
17
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.4
6.2
29
94
L28
ICPC
Limited function/disability (L)
2.9
6.2
38
147
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
7.0
6.1
14
21
R49.01
ICD-10 Finland
Functional dysphonia
6.4
6.1
15
25
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
10.4
6.1
11
11
C03DA01
ATC
spironolactone; oral
3.5
6.1
27
84
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.0
6.0
35
132
S97
ICPC
Chronic ulcer skin
5.3
6.0
17
34

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
90
20
69.91
158.81
3.0
1.3
—
—
—
0
0
148
135
25.56
155.06
4.1
1.7
1.0
1.4
g/l
0.90
138
126
86
20
65.16
149.92
2.5
1.3
2.1
3.2
g/l
1.16
69
15
77
20
55.29
130.12
2.2
1.7
1.3
0.9
e9/l
—
52
6
110
143
12.99
87.01
1.8
1.2
81.9
303.7
u/ml
0.77
101
135
55
18
38.93
86.11
2.1
1.7
435.6
807.2
e6/l
0.88
48
13
49
20
30.26
71.01
2.1
1.6
929.4
804.1
e6/l
—
21
9
47
22
26.10
64.55
3.8
3.1
—
—
—
0
0
168
485
8.57
63.11
4.1
1.4
1.7
2.2
g/l
4.63
142
301
183
661
7.67
51.62
18.5
6.1
—
—
—
0
0
220
1084
9.84
40.43
20.8
5.9
1.9
2.0
e9/l
0.24
220
968
89
224
5.63
35.37
2.9
1.5
—
—
—
0
0
226
1221
10.21
35.18
25.1
9.7
4.0
3.9
e9/l
0.23
221
1063
131
462
4.87
34.37
9.2
3.9
—
—
—
0
0
82
200
5.62
33.60
3.5
2.1
309.2
362.9
nmol/l
1.32
74
185
90
239
5.33
33.42
2.5
1.5
—
—
—
0
0
24
13
20.32
30.35
2.4
1.2
—
—
—
0
0
91
271
4.72
28.89
3.5
2.0
—
—
—
0
0
130
533
4.01
26.19
14.8
7.7
—
—
—
0
0
92
303
4.23
25.14
1.9
1.4
475.6
451.3
titre
0.08
18
71
87
292
4.04
22.90
3.8
2.2
11.9
13.9
umol/l
1.61
82
273
21
0
+∞
22.21
1.6
0.0
—
—
—
0
0
61
163
4.63
21.67
7.8
4.5
0.6
0.6
%
0.06
28
41
22
19
12.60
21.64
1.4
1.3
0.4
0.1
u/ml
—
13
7
77
247
4.07
21.45
3.7
2.3
20.3
23.5
%
1.02
71
214
185
1071
3.83
20.18
9.8
6.3
8.6
10.7
umol/l
3.76
180
1019
170
944
3.52
19.57
16.8
7.2
1.2
1.2
mmol/l
0.48
147
810
60
171
4.31
19.48
8.9
4.8
0.1
0.1
%
0.04
33
53
62
183
4.18
19.19
8.9
4.7
0.8
0.9
%
0.17
33
61
158
862
3.28
18.27
17.1
6.6
1.2
1.2
mmol/l
1.23
152
793
46
112
4.81
18.16
2.3
2.3
—
—
—
0
0
55
164
4.02
16.64
9.2
4.9
0.0
0.0
%
0.80
28
46
226
1597
5.49
16.43
21.6
7.3
78.0
78.0
u/l
0.01
221
1496
18
19
10.13
15.40
3.1
3.3
—
—
—
0
0
129
696
2.77
14.04
8.8
6.5
1.0
1.1
inr
1.63
39
220
17
19
9.53
13.93
1.2
1.7
—
—
—
0
0
17
19
9.53
13.93
1.2
1.7
—
—
—
0
0
17
19
9.53
13.93
1.2
1.7
—
—
—
0
0
17
19
9.53
13.93
1.2
1.7
—
—
—
0
0
29
60
5.34
13.70
1.9
1.5
297.6
274.1
ug/g
0.24
17
33
42
120
4.01
13.34
10.2
4.4
7.4
7.4
ph
—
5
14
97
464
2.79
13.17
2.3
1.9
—
—
—
0
0
46
144
3.69
12.81
4.8
2.6
76.3
71.6
e9/l
0.32
40
111
103
518
2.69
12.57
12.2
4.8
—
—
—
0
0
71
296
2.96
12.37
2.2
2.5
212.2
119.1
ug/g
0.59
53
233
24
46
5.67
12.28
1.1
1.3
—
—
—
0
0
67
273
2.99
12.14
1.3
1.2
—
—
—
0
0
95
468
2.67
11.98
2.9
2.0
1.4
1.1
mg/l
0.42
75
357
154
958
2.59
11.88
25.3
8.5
0.0
0.0
e9/l
1.02
140
779
128
731
2.55
11.84
2.6
1.9
96.2
98.3
pmol/l
0.16
69
369
151
933
2.57
11.78
4.8
2.7
126.3
91.0
ug/l
1.15
146
862
116
636
2.54
11.65
3.9
2.3
—
—
—
0
0
120
672
2.52
11.48
5.3
3.3
25.6
26.9
ng/l
0.05
78
421
22
42
5.65
11.28
6.3
3.8
3.5
4.4
e9/l
0.82
22
42
22
43
5.52
11.00
9.1
4.3
54.2
55.7
%
0.16
22
43
108
587
2.48
10.89
8.6
3.7
7.4
7.4
ph
0.40
25
107
60
244
2.92
10.81
1.5
1.3
—
—
—
0
0
14
17
8.67
10.72
1.1
2.0
—
—
—
0
0
199
1443
2.89
10.61
10.0
4.1
—
—
—
0
0
12
12
10.46
10.52
1.2
1.1
—
—
—
0
0
32
89
3.98
10.48
12.4
4.9
—
—
—
0
0
40
130
3.47
10.46
1.8
1.2
—
—
—
0
0
43
147
3.33
10.38
1.6
1.5
—
—
—
0
0
28
71
4.32
10.35
5.6
4.4
0.4
0.5
g/l
0.10
14
27
158
1040
2.42
10.13
8.3
4.7
0.0
0.0
estimate
0.50
34
210
134
822
2.36
10.09
5.6
3.0
—
—
—
0
0
159
1051
2.42
10.07
6.5
3.4
0.0
0.0
estimate
0.00
34
199
24
55
4.72
10.04
3.7
2.7
—
—
—
0
0
47
175
3.08
9.84
12.7
11.5
1.9
1.4
mmol/l
0.20
40
141
26
66
4.28
9.59
2.7
2.2
1.6
1.5
g/l
0.06
20
58
32
96
3.68
9.40
6.6
10.2
—
—
—
0
0
65
296
2.62
9.32
2.1
1.7
1344.6
1170.6
nmol/l
0.77
55
213
155
1036
2.31
9.24
6.5
3.3
0.0
0.0
estimate
0.00
33
206
17
31
5.81
9.10
1.1
1.4
—
—
—
0
0
22
51
4.63
9.07
1.3
1.6
—
—
—
0
0
80
407
2.42
9.04
6.1
2.4
4.6
5.9
e6/l
0.53
75
360
49
197
2.85
8.91
2.7
1.4
—
—
—
0
0
62
282
2.60
8.87
2.0
1.5
—
—
—
0
0
87
465
2.34
8.75
6.2
3.2
—
—
—
0
0
24
63
4.11
8.46
5.9
5.5
—
—
—
0
0
15
26
6.07
8.43
1.0
1.4
—
—
nmol/l
—
0
0
29
89
3.56
8.22
1.3
1.2
—
—
—
0
0
10
11
9.43
8.14
1.6
1.4
1.8
2.0
mmol/l
—
10
11
117
725
2.16
8.06
8.8
3.6
13.9
55.6
e6/l
2.91
89
489
24
66
3.92
7.95
19.0
9.7
—
—
—
0
0
15
28
5.64
7.83
1.3
1.3
420.7
356.0
pmol/l
—
10
22
39
149
2.92
7.74
3.2
2.0
4.2
4.1
e9/l
0.05
25
121
14
25
5.87
7.63
1.7
1.4
—
—
—
0
0
95
552
2.17
7.63
8.1
3.0
0.4
0.4
e6/l
0.12
81
402
74
391
2.27
7.49
2.1
1.6
—
—
—
0
0
241
2141
4.91
7.26
49.8
12.1
16.9
21.1
mg/l
1.94
224
1645
13
23
5.91
7.14
1.8
1.3
—
—
—
0
0
14
27
5.43
7.05
4.1
2.7
—
—
—
0
0
77
423
2.19
7.04
2.1
1.5
24.2
22.0
nmol/l
0.54
67
357
16
35
4.82
7.04
2.0
1.6
—
—
—
0
0
15
31
5.08
7.02
1.3
1.3
—
—
—
0
0
26
83
3.38
6.94
2.3
1.6
—
—
—
0
0
99
602
2.07
6.93
8.0
3.0
12.3
58.4
e6/l
2.34
84
451
11
17
6.72
6.83
1.1
1.1
2.6
3.2
u/ml
—
5
6
38
153
2.75
6.83
1.6
1.3
—
37.5
—
0
12
14
28
5.24
6.79
2.5
1.3
—
—
—
0
0
37
148
2.76
6.73
31.2
9.8
—
—
—
0
0
92
550
2.07
6.70
8.1
2.9
—
—
—
0
0
13
25
5.43
6.56
1.5
1.9
—
—
—
0
0
84
494
2.06
6.34
3.1
2.7
4179.2
6320.3
umol/l
0.20
77
430
26
88
3.18
6.33
1.5
1.5
—
—
—
0
0
23
72
3.42
6.32
1.1
1.2
—
—
—
0
0
17
43
4.17
6.28
1.4
1.8
—
—
—
0
0
40
175
2.53
6.09
1.8
1.2
33.4
153.9
iu/ml
3.48
19
68
64
344
2.16
6.08
3.8
3.4
159.7
220.0
ng/l
0.18
32
233
39
169
2.55
6.05
8.4
4.7
—
—
—
0
0
10
16
6.47
6.00
1.1
1.1
—
—
—
0
0
69
388
2.08
5.81
1.5
1.3
13.4
31.7
iu/ml
2.46
20
131
16
41
4.10
5.81
1.8
1.1
68.6
25.4
iu/ml
—
7
7
16
41
4.10
5.81
2.1
2.3
123.1
133.6
g/l
—
8
27
13
28
4.84
5.80
1.2
1.0
8.3
3.4
u/ml
—
7
5
68
381
2.08
5.78
1.4
1.3
5.2
8.1
u/ml
0.30
19
157
89
554
1.94
5.61
7.6
3.4
0.0
0.0
estimate
0.50
34
210
40
183
2.41
5.53
1.9
1.4
—
—
—
0
0
39
179
2.40
5.35
2.0
1.4
—
—
—
0
0
16
45
3.73
5.13
1.4
1.6
110.7
111.3
u/ml
—
6
7
14
36
4.06
5.06
1.6
1.2
—
—
—
0
0
23
83
2.95
5.03
17.0
16.3
—
—
—
0
0
13
32
4.23
4.96
1.6
1.8
—
—
—
0
0
91
597
1.83
4.74
6.4
2.7
—
—
—
0
0
12
29
4.30
4.68
1.4
2.1
—
—
—
0
0
14
39
3.74
4.55
1.2
1.2
0.9
2.9
u/ml
—
7
18
14
40
3.65
4.40
1.6
3.0
—
—
—
0
0
9
12
7.73
4.39
1.4
1.0
—
—
—
0
0
64
386
1.89
4.29
1.9
1.7
486.9
459.3
pmol/l
0.37
56
321
14
41
3.56
4.25
2.2
1.4
38401.6
23473.6
e6/l
—
9
28
242
2245
3.77
4.14
34.8
11.0
—
—
—
0
0
118
860
1.71
4.14
2.5
2.0
—
—
—
0
0
23
94
2.59
4.02
10.2
12.8
26.1
24.9
mmol/l
0.95
23
88
12
33
3.77
3.97
1.2
1.1
0.6
0.7
u/ml
—
6
13
10
24
4.30
3.92
1.3
1.3
—
—
—
0
0
195
1664
1.79
3.55
6.5
4.0
14.7
14.6
pmol/l
0.22
184
1526
9
17
5.45
3.54
1.4
1.3
—
—
—
0
0
81
552
1.69
3.53
4.9
3.6
—
—
—
0
0
12
36
3.45
3.52
3.7
2.6
—
—
—
0
0
7
10
7.16
3.38
3.1
3.0
—
—
—
0
0
8
14
5.86
3.37
1.0
1.1
—
—
—
0
0
8
14
5.86
3.37
1.0
1.2
—
—
—
0
0
96
691
1.63
3.36
3.6
3.1
2.3
2.4
mmol/l
1.07
81
610
6
7
8.74
3.28
3.8
3.9
—
—
—
0
0
6
7
8.74
3.28
1.0
1.0
2917.3
1697.6
miu/ml
—
6
7
30
155
2.06
3.11
8.2
3.1
—
—
—
0
0
8
16
5.13
3.07
1.0
1.5
—
—
—
0
0
44
261
1.83
3.07
1.7
1.7
—
—
—
0
0
11
35
3.24
2.97
57.8
3.3
—
—
—
0
0
10
30
3.43
2.94
2.4
2.2
—
—
—
0
0
10
30
3.43
2.94
2.2
5.5
—
—
—
0
0
7
13
5.50
2.89
1.4
1.1
—
—
—
0
0
77
542
1.61
2.88
1.4
1.3
0.6
1.4
u/ml
1.40
21
157
6
9
6.80
2.88
1.3
1.1
—
—
—
0
0
6
9
6.80
2.88
1.0
1.4
—
—
—
0
0
66
448
1.64
2.86
6.6
3.4
1.0
1.0
kg/l
—
6
59
219
1977
1.89
2.78
7.4
4.7
1.8
2.5
mu/l
0.59
214
1832
13
48
2.80
2.76
1.6
1.3
—
—
—
0
0
5
6
8.47
2.76
1.4
1.0
—
—
—
0
0
5
6
8.47
2.76
2.6
1.7
—
—
—
0
0
6
10
6.12
2.71
6.5
3.1
—
—
—
0
0
6
10
6.12
2.71
1.3
1.2
—
—
—
0
0
81
585
1.57
2.70
3.9
3.2
6.8
7.6
mmol/l
0.78
75
498
9
24
3.85
2.70
3.8
1.6
32.3
33.4
pg
—
9
24
20
94
2.23
2.63
1.8
2.4
388.4
3054.2
u/l
—
6
35
11
39
2.90
2.51
4.5
2.9
9.0
9.0
kpa
0.02
11
39
11
39
2.90
2.51
4.6
2.9
4.7
5.0
kpa
0.46
11
39
9
26
3.55
2.50
1.6
2.1
—
—
—
0
0
9
26
3.55
2.50
2.1
1.0
—
—
—
0
0
13
51
2.63
2.48
1.1
1.1
—
—
—
0
0
9
27
3.42
2.41
1.7
1.2
—
—
—
0
0
6
12
5.09
2.41
1.5
1.4
—
—
—
0
0
6
12
5.09
2.41
1.8
2.0
—
—
—
0
0
6
12
5.09
2.41
1.8
1.1
—
—
—
0
0
5
8
6.35
2.38
2.6
3.6
37.5
47.3
%
—
5
8
5
8
6.35
2.38
1.0
2.4
—
—
—
0
0
6
13
4.70
2.28
2.2
2.2
9.1
10.5
umol/l
—
6
13
7
18
3.97
2.27
1.0
1.0
—
—
—
0
0
10
36
2.85
2.23
1.1
1.1
—
—
—
0
0
12
51
2.42
1.98
1.1
1.1
—
—
—
0
0
8
27
3.03
1.95
1.1
1.1
—
—
—
0
0
29
175
1.74
1.93
8.7
3.4
—
—
—
0
0
68
509
1.46
1.85
3.9
3.2
71.4
194.2
mg/l
0.43
43
314
6
17
3.59
1.85
1.0
1.3
—
—
—
0
0
6
17
3.59
1.85
1.5
1.7
0.8
1.1
g/l
—
6
17
6
17
3.59
1.85
6.5
2.6
—
—
—
0
0
78
600
1.44
1.84
5.5
3.1
—
—
—
0
0
76
582
1.44
1.83
1.7
1.7
1.3
1.4
mmol/l
0.61
69
493
5
12
4.23
1.83
1.6
1.4
—
—
—
0
0
8
29
2.82
1.80
1.4
1.1
—
—
—
0
0
15
74
2.09
1.79
1.2
1.1
—
—
—
0
0
13
252
0.49
1.76
1.4
1.4
—
—
—
0
0
32
204
1.65
1.76
3.3
4.1
4.1
28.6
ug/l
0.62
24
167
8
30
2.72
1.74
2.5
2.1
1.9
1.6
mmol/l
—
8
30
49
350
1.50
1.67
3.7
2.4
2.4
2.4
mmol/l
0.31
40
308
6
19
3.21
1.67
1.7
1.0
—
—
—
0
0
5
14
3.62
1.62
2.0
1.1
—
—
—
0
0
5
14
3.62
1.62
1.4
1.1
—
—
g/l
—
0
0
29
185
1.64
1.60
1.2
1.2
—
—
—
0
0
21
125
1.74
1.49
3.8
2.2
—
—
—
0
0
12
59
2.09
1.46
2.5
1.6
2.7
5.7
iu/l
—
5
22
5
16
3.17
1.44
1.0
1.2
—
—
—
0
0
68
847
0.73
1.41
2.6
2.6
—
—
—
0
0
9
40
2.30
1.41
1.2
1.9
—
—
—
0
0
69
543
1.37
1.40
4.6
3.9
20.8
9.3
mg/mmol
0.38
47
331
9
41
2.24
1.38
1.0
1.1
—
—
—
0
0
6
23
2.65
1.37
4.0
1.3
—
—
—
0
0
9
44
2.08
1.28
2.3
2.0
0.9
0.8
nmol/l
—
9
36
9
44
2.08
1.28
3.0
1.5
—
—
—
0
0
9
171
0.51
1.23
1.6
1.4
—
—
—
0
0
8
39
2.09
1.16
1.1
1.2
—
—
—
0
0
7
30
2.37
1.13
1.0
1.3
—
—
—
0
0
38
280
1.42
1.13
1.3
1.2
—
—
—
0
0
7
32
2.22
1.09
2.1
1.3
—
—
—
0
0
7
33
2.15
1.06
2.0
2.5
—
—
—
0
0
16
245
0.63
0.99
2.3
1.9
—
—
—
0
0
6
27
2.25
0.94
1.0
1.1
—
—
—
0
0
17
112
1.56
0.87
1.0
1.1
—
—
—
0
0
35
267
1.36
0.87
1.7
1.5
—
—
—
0
0
6
33
1.84
0.79
104.0
2.4
70.0
64.1
%
—
6
33
212
2025
1.32
0.79
5.0
4.2
5.9
5.8
mmol/l
0.62
201
1885
12
76
1.61
0.73
1.6
1.5
—
—
—
0
0
152
1407
1.21
0.72
4.8
3.3
—
—
—
0
0
200
1906
1.25
0.69
6.7
5.1
39.0
38.9
mmol/mol
0.04
192
1788
9
59
1.54
0.69
1.4
1.2
—
—
—
0
0
11
76
1.47
0.49
1.9
2.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
5
36
1.40
0.38
2.8
2.1
—
—
—
0
0
206
2003
1.16
0.37
4.1
3.8
1.4
1.3
mmol/l
1.89
197
1869
12
90
1.35
0.36
1.8
2.5
—
—
—
0
0
6
47
1.28
0.32
1.2
1.1
—
—
—
0
0
10
131
0.75
0.31
2.8
1.8
—
—
—
0
0
12
93
1.31
0.30
2.9
3.2
—
—
—
0
0
38
338
1.15
0.28
3.2
4.3
1.6
1.7
ug/l
0.31
38
305
12
95
1.28
0.27
2.7
2.3
—
—
—
0
0
12
98
1.24
0.21
1.8
2.4
—
—
—
0
0
12
98
1.24
0.21
1.8
2.4
—
—
—
0
0
12
98
1.24
0.21
1.8
2.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
6
52
1.16
0.19
2.2
3.2
—
—
—
0
0
7
61
1.15
0.17
1.1
2.4
—
—
—
0
0
8
70
1.15
0.16
1.9
3.8
—
—
—
0
0
17
150
1.14
0.15
1.2
1.2
—
—
—
0
0
198
2009
0.93
0.14
38.2
13.2
40.0
40.3
%
0.32
153
1570
212
2093
1.09
0.14
4.6
4.2
4.8
4.8
mmol/l
0.09
205
1963
211
2085
1.08
0.13
4.7
4.2
1.6
1.5
mmol/l
0.57
204
1950
66
634
1.06
0.11
1.7
1.5
—
—
—
0
0
11
97
1.14
0.09
1.9
2.0
—
—
—
0
0
13
117
1.12
0.08
1.2
1.1
—
—
—
0
0
213
2121
1.03
0.02
5.1
4.7
2.8
2.9
mmol/l
0.60
203
1985
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint D3_DEF_IGG and mortality.

Females

Parameter HR [95% CI] p-value
D3_DEF_IGG 2.525 [1.85, 3.45] < 0.001
Birth year 1.0 [0.99, 1.01] 0.938

During the follow-up period (1.1.1998 — 31.12.2019), 72 out of 613 females with D3_DEF_IGG died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have D3_DEF_IGG.

N-year risk Females Males
1 0.284% No data
5 1.813% No data
10 4.498% No data
15 8.646% No data
20 14.401% No data

Relationships between endpoints

Index endpoint: D3_DEF_IGG – Selective deficiency of immunoglobulin G [IgG] subclasses

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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