No definition available.
Selective deficiency of immunoglobulin G [IgG] subclasses
DOID EFO Endpoint Browser PheWeb
D3_DEF_IGG
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
257 |
4. Check minimum number of eventsNone |
257 |
5. Include endpointsNone |
257 |
6. Filter based on genotype QC (FinnGen only) |
245 |
Control definitions (FinnGen only)
- Control exclude
- D3_IMMUNEMECHANISM
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D80
- Name in latin
- Deficientia selectiva subclassium immunoglobulini G
Similar endpoints
↥List of similar endpoints to
Selective deficiency of immunoglobulin G [IgG] subclasses
based on the number of shared cases.
Similar with more cases:
- Immunodeficiency with predominantly antibody defects
- Immunodeficiencies
- Certain disorders involving the immune mechanism
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1014 | 665 | 344 |
| Only index persons | 956 | 637 | 319 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 43.56 | 45.95 | 38.66 |
| Only index persons | 44.64 | 46.75 | 40.42 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 245 | 181 | 64 |
| Unadjusted period prevalence (%) | 0.06 | 0.06 | 0.03 |
| Median age at first event (years) | 47.85 | 47.75 | 48.14 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 257
- Matched controls
- 2570
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
+∞
307.7
257
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
27.6
114.3
86
46
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
28.8
97.2
70
33
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
+∞
94.8
85
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
19.6
87.3
76
54
J01MA12
ATC
levofloxacin; systemic
11.3
87.0
140
247
J01MA14
ATC
moxifloxacin; systemic
13.6
84.0
97
110
120
Kela drug reimbursment
Hypogammaglobulinaemia
+∞
80.5
73
*
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
+∞
79.4
72
*
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
28.8
75.2
53
23
WW200
NOMESCO Finland
Immunization
28.6
69.7
49
21
R03DC03
ATC
montelukast; oral
8.9
69.1
130
265
J45.1
ICD-10 Finland
Nonallergic asthma
12.0
69.0
83
98
J45.0
ICD-10 Finland
Predominantly allergic asthma
10.0
63.5
90
131
J45.9
ICD-10 Finland
Asthma, unspecified
8.1
63.4
134
305
H02AB06
ATC
prednisolone; systemic
12.4
62.5
220
831
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
+∞
62.0
57
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
10.2
61.2
84
117
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
+∞
58.6
54
*
ZX120
NOMESCO Finland
Intravenous
9.4
58.6
87
133
J47
ICD-10 Finland
Bronchiectasis
25.5
56.3
41
19
TDM10
NOMESCO Finland
Puncture of maxillary antrum
14.3
56.2
56
49
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
7.1
54.4
123
293
R03BB04
ATC
tiotropium bromide; inhalant
10.2
53.9
71
93
J45.8
ICD-10 Finland
Mixed asthma
21.6
53.7
42
23
H02AB07
ATC
prednisone; oral
7.7
51.8
94
178
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
10.6
49.8
62
75
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.8
45.9
190
757
TPH04
NOMESCO Finland
Cathetrisation of vein
6.0
44.7
121
332
R50.9
ICD-10 Finland
Fever, unspecified
6.3
42.8
96
221
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
8.7
41.9
61
89
J18.9
ICD-10 Finland
Pneumonia, unspecified
5.8
41.6
110
293
R03AK08
ATC
formoterol and beclometasone; inhalant
11.7
41.3
46
47
R03DA04
ATC
theophylline; systemic, rectal
13.0
39.0
40
36
UGC12
NOMESCO Finland
Flexible bronchoscopy
10.1
38.7
48
57
R03AC12
ATC
salmeterol; inhalant
11.8
38.2
42
42
R03BA02
ATC
budesonide; inhalant
5.4
37.7
108
305
R03AK06
ATC
salmeterol and fluticasone; inhalant
5.9
37.3
87
205
J01FA15
ATC
telithromycin; oral
6.5
36.6
73
148
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
12.9
36.2
37
33
A49.9
ICD-10 Finland
Bacterial infection, unspecified
7.2
36.1
62
108
H02AB09
ATC
hydrocortisone; systemic
13.8
35.8
35
29
D80.0
ICD-10 Finland
Hereditary hypogammaglobulinaemia
+∞
35.2
33
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
8.0
34.7
53
81
A07AA02
ATC
nystatin; oral
8.9
34.3
47
63
J01FF01
ATC
clindamycin; systemic
4.7
33.8
128
446
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
5.0
33.8
104
308
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.7
33.2
77
179
J01.0
ICD-10 Finland
Acute maxillary sinusitis
4.6
32.9
134
491
J01MA02
ATC
ciprofloxacin; systemic
4.6
32.3
151
611
J01FA06
ATC
roxithromycin; oral
4.7
32.1
169
746
H02AB04
ATC
methylprednisolone; systemic
5.3
32.0
83
212
UDH02
NOMESCO Finland
Rhinopharyngoscopy
7.0
31.9
56
99
J46
ICD-10 Finland
Status asthmaticus
12.9
31.5
32
28
C01CA24
ATC
epinephrine; parenteral
6.5
30.8
58
110
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.4
30.8
125
453
Z01.8
ICD-10 Finland
Other specified special examinations
4.6
30.6
108
352
J01FA09
ATC
clarithromycin; systemic
4.3
30.1
144
585
R03AC13
ATC
formoterol; inhalant
8.7
29.8
41
55
GD1AD
NOMESCO Finland
Thorax CT examination
9.6
28.6
36
43
J45
ICD-10 Finland
Asthma
5.7
28.4
63
139
XQ800
NOMESCO Finland
Prick test
6.1
28.1
56
112
C03CA01
ATC
furosemide; systemic
4.4
27.5
96
307
XG474
NOMESCO Finland
Exhalation nntrogen oxide
10.1
27.4
33
37
R03BB01
ATC
ipratropium bromide; inhalant
10.9
27.3
31
32
R03BA05
ATC
fluticasone; inhalant
4.3
27.2
99
326
UJF30
NOMESCO Finland
Ileoscopy through colon
5.5
26.4
60
135
R06.0
ICD-10 Finland
Dyspnoea
4.0
25.8
109
397
M79.0
ICD-10 Finland
Rheumatism, unspecified
8.7
25.7
35
46
6BA02, ,
NOMESCO Finland
144.0
25.1
26
*
D84.18
ICD-10 Finland
Other specified defect in the complement system
+∞
24.4
23
*
R03BA01
ATC
beclometasone; inhalant
4.6
24.3
72
201
R01AD05
ATC
budesonide; nasal
5.8
24.1
50
103
XG410
NOMESCO Finland
Flow-volume spirometry
8.8
24.0
32
41
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
4.4
23.7
198
1119
D80.2
ICD-10 Finland
Selective deficiency of immunoglobulin A [IgA]
+∞
23.3
22
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.9
22.9
59
147
N03AX16
ATC
[U] pregabalin
3.8
22.9
102
381
XW000
NOMESCO Finland
Bone marrow biopsy
9.2
22.7
29
35
R03BA08
ATC
ciclesonide; inhalant
4.9
22.4
57
140
R01AD08
ATC
fluticasone; nasal
3.6
22.4
126
546
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
4.2
22.1
76
236
ZX112
NOMESCO Finland
Subcutaneous
9.9
21.6
26
29
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.4
21.1
126
562
J01FA10
ATC
azithromycin; systemic
4.5
21.1
212
1310
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
5.9
21.1
42
83
R03AC02
ATC
salbutamol; inhalant
4.0
21.0
198
1170
R03AC03
ATC
terbutaline; inhalant
4.1
20.7
69
209
R03AK07
ATC
formoterol and budesonide; inhalant
3.6
20.6
93
347
M05BA04
ATC
alendronic acid; oral
5.8
20.3
41
82
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
39.3
20.2
25
7
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
6.6
20.2
35
60
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
8.1
19.9
28
38
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
113.9
19.9
21
*
TAB00
NOMESCO Finland
Lumbar puncture
6.0
19.9
38
72
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
3.7
19.6
190
1120
J32.4
ICD-10 Finland
Chronic pansinusitis
22.3
19.5
28
14
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
6.5
19.4
34
59
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
3.3
18.9
113
498
J31.0
ICD-10 Finland
Chronic rhinitis
4.5
18.7
53
141
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.6
18.7
51
132
R01AD09
ATC
mometasone; nasal
3.3
18.6
169
945
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
6.2
18.4
34
62
N03AX12
ATC
[U] gabapentin; oral
3.6
18.1
78
279
J20
ICD-10 Finland
Acute bronchitis
4.1
18.0
58
170
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.6
18.0
37
75
TGC00
NOMESCO Finland
Bronchial lavation
17.3
18.0
28
18
D83.0
ICD-10 Finland
Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
+∞
17.9
17
*
D83.9
ICD-10 Finland
Common variable immunodeficiency, unspecified
+∞
17.9
17
*
A02BC05
ATC
esomeprazole; systemic
3.1
17.8
143
740
J01.9
ICD-10 Finland
Acute sinusitis, unspecified
6.3
17.8
32
57
N06AX21
ATC
duloxetine; oral
3.8
17.5
64
205
A03FA01
ATC
metoclopramide; systemic, rectal
3.2
17.2
94
389
N02AA05
ATC
oxycodone; systemic
3.7
17.2
65
213
J02AC01
ATC
fluconazole; systemic
3.1
17.1
154
844
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.7
16.9
44
109
WZC30
NOMESCO Finland
Teaching
3.5
16.9
73
261
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
29.9
16.8
22
8
J01AA02
ATC
doxycycline; systemic
5.4
16.7
233
1651
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.9
16.5
57
175
R01BA52
ATC
pseudoephedrine, combinations; oral
3.0
16.4
114
539
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.7
16.3
42
103
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.2
16.1
48
132
N02AX02
ATC
tramadol; systemic, rectal
2.9
16.0
144
779
N05BA01
ATC
diazepam; systemic, rectal
3.7
16.0
60
195
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.6
15.9
63
212
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
40.8
15.6
19
5
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.9
15.5
52
156
JN3AD
NOMESCO Finland
Abdominal CT examination
4.0
15.5
50
146
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
5.2
15.4
34
73
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
5.9
15.3
29
54
R01AD58
ATC
fluticasone, combinations; nasal
3.0
15.3
99
446
R06AE09
ATC
levocetirizine; oral
3.4
15.1
66
236
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.9
14.9
49
145
SPAT1255
SPAT
Intravenous administration of medicine
5.7
14.8
29
56
A41.9
ICD-10 Finland
Sepsis, unspecified
13.7
14.7
25
20
D84.9
ICD-10 Finland
Immunodeficiency, unspecified
+∞
14.7
14
*
D80.6
ICD-10 Finland
Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
+∞
14.7
14
*
R06AE07
ATC
cetirizine; oral
2.8
14.6
153
884
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.9
14.5
48
142
C03DA01
ATC
spironolactone; oral
4.0
14.5
47
137
N06AA09
ATC
amitriptyline; systemic
4.0
14.4
45
128
R01BA51
ATC
phenylpropanolamine, combinations; oral
3.6
14.1
55
182
R13
ICD-10 Finland
Dysphagia
4.7
14.1
35
83
Z3231
NOMESCO Finland
Registered nurse
2.8
14.1
102
485
XF400
NOMESCO Finland
ECG with 12 standard connections
3.4
13.9
59
206
A01AB09
ATC
miconazole; local oral
4.3
13.9
39
102
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
4.5
13.8
36
89
R53
ICD-10 Finland
Malaise and fatigue
2.9
13.7
90
405
ZXA10
NOMESCO Finland
Bilateral
3.2
13.7
69
268
GD1DG
NOMESCO Finland
Extremely extensive MRI examination of pleura with high field magnet
+∞
13.7
13
*
WE300
NOMESCO Finland
Profylactive therapy of malignancy with biomoidiers
+∞
13.7
13
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.9
13.6
44
128
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.7
13.4
137
771
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.0
13.4
78
329
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.2
13.3
38
101
R01AD12
ATC
fluticasone furoate; nasal
2.7
13.2
117
612
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.3
13.2
58
207
R06AX27
ATC
desloratadine; oral
2.7
13.2
110
559
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.5
13.1
51
168
J01DA06
ATC
[U] cefuroxime
3.2
13.1
65
249
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
12.5
13.1
23
20
N03AX11
ATC
topiramate; oral
5.8
13.0
25
47
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.8
13.0
45
137
P01BA02
ATC
hydroxychloroquine; oral
3.9
13.0
42
122
R03AK03
ATC
[U] fenoterol and ipratropium bromide
6.2
13.0
23
40
E0000UV, ,
ATC
2.6
12.9
139
798
Z3226
NOMESCO Finland
Physiotherapist
3.0
12.9
73
302
A02BC02
ATC
pantoprazole; systemic
3.0
12.8
195
1325
UJF32
NOMESCO Finland
Coloscopy
2.8
12.6
86
393
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
5.8
12.6
24
45
S01GX01
ATC
cromoglicic acid; ophthalmic
2.8
12.5
84
381
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.5
12.5
32
78
N03AE01
ATC
clonazepam; systemic
4.7
12.3
30
70
J05AB11
ATC
valaciclovir; oral
3.0
12.3
68
277
R03DC01
ATC
zafirlukast; oral
14.3
12.2
20
15
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
3.6
12.1
45
144
R52.9
ICD-10 Finland
Pain, unspecified
3.6
12.1
45
144
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.8
12.0
29
67
JN4BD
NOMESCO Finland
Extensive body CT
3.7
12.0
43
134
Z2221
NOMESCO Finland
Medical doctor
2.6
12.0
99
496
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.2
11.9
57
213
WX002
NOMESCO Finland
Sedation and analgesia
2.9
11.8
68
283
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
10.0
11.8
23
25
M36.8*D80.1
ICD-10 Finland
Systemic disorders of connective tissue in hypogammaglobulinaemia
+∞
11.5
11
*
P01AB01
ATC
metronidazole; oral, rectal
2.5
11.5
138
820
M79.7
ICD-10 Finland
Fibromyalgia
5.0
11.5
26
57
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.6
11.4
42
133
J01DB01
ATC
cefalexin; oral
4.6
11.4
237
1853
N05CF01
ATC
zopiclone; oral
2.5
11.3
105
553
R06AX22
ATC
ebastine; oral
2.8
11.3
71
309
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
26.4
11.3
15
6
UKC02
NOMESCO Finland
Cystoscopy
3.4
11.3
46
156
R05
ICD-10 Finland
Cough
2.7
11.2
77
350
A03CA02
ATC
clidinium and psycholeptics; oral
4.9
11.2
26
58
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
6.1
11.2
20
35
WW500
NOMESCO Finland
Blood transfusion
5.8
11.1
21
39
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.9
11.0
35
100
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
45.4
11.0
13
*
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
45.4
11.0
13
*
L04AX01
ATC
azathioprine; systemic
5.5
11.0
22
43
N06AX11
ATC
mirtazapine; oral
2.4
11.0
114
631
J01DA01
ATC
[U] cefalexin
2.6
10.9
185
1275
XG466
NOMESCO Finland
Sleep oxymetry
8.6
10.9
23
29
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
10.8
91
456
ZYC01
NOMESCO Finland
Remote contact by phone
4.0
10.8
33
92
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
4.8
10.7
25
56
R51.80
ICD-10 Finland
Headache
2.7
10.7
69
303
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
62.7
10.7
12
*
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
5.2
10.7
23
48
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.3
10.7
46
161
J01
ICD-10 Finland
Acute sinusitis
4.3
10.6
29
74
C07AB07
ATC
bisoprolol; oral
2.4
10.6
128
755
A07AA09
ATC
vancomycin; oral
17.0
10.5
16
10
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
17.0
10.5
16
10
N05CD07
ATC
temazepam; oral
3.6
10.5
38
119
3XA02, ,
NOMESCO Finland
+∞
10.5
10
*
D83.8
ICD-10 Finland
Other common variable immunodeficiencies
+∞
10.5
10
*
R60.9
ICD-10 Finland
Oedema, unspecified
5.1
10.5
23
49
DMB10
NOMESCO Finland
Radical maxillary antrotomy
34.1
10.4
13
*
A01AB04
ATC
amphotericin B; local oral
5.0
10.2
23
50
M35.7
ICD-10 Finland
Hypermobility syndrome
10.7
10.2
19
19
ZXE00
NOMESCO Finland
One hour or less
2.3
10.1
123
723
X59
ICD-10 Finland
Exposure to unspecified factor
2.7
10.1
68
305
J32.1
ICD-10 Finland
Chronic frontal sinusitis
21.0
9.9
14
7
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
9.9
112
637
R96
ICPC
Asthma
3.4
9.8
38
124
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.4
9.8
97
520
H04.10
ICD-10 Finland
Dry eye syndrome
2.9
9.8
51
199
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.0
9.7
47
176
H60.9
ICD-10 Finland
Otitis externa, unspecified
3.6
9.7
34
104
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
3.1
9.6
46
171
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.3
9.6
40
137
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.6
9.6
69
319
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.8
9.5
31
90
L04AX03
ATC
methotrexate; systemic
3.2
9.5
42
149
GD1CG
NOMESCO Finland
Extensive examination of lungs and pleura with high intensity magnet
103.7
9.5
10
*
R5140
NOMESCO Finland
Monitoring the use of the aid
3.1
9.5
43
155
ZXD10
NOMESCO Finland
Scheduled procedure
2.3
9.5
113
655
SPAT1262
SPAT
Handing over of treatment supplies
2.9
9.5
52
209
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
22.7
9.4
13
6
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
7.8
9.4
21
29
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
9.4
118
698
NF1AA
NOMESCO Finland
Hip X-ray examination
3.8
9.4
30
86
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.6
9.3
23
54
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
8.2
9.3
20
26
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.7
9.3
61
269
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
4.0
9.3
28
77
A02BC01
ATC
omeprazole; systemic
2.4
9.3
85
439
A06AD11
ATC
lactulose; oral
3.1
9.3
43
157
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
5.1
9.2
20
42
A03
ICPC
Fever
2.5
9.2
68
318
J01DC02
ATC
cefuroxime; systemic
4.0
9.2
27
73
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.9
9.1
49
194
WZC00
NOMESCO Finland
Treatment plan or consultation
2.3
9.1
114
671
ZXA00
NOMESCO Finland
Right side
2.4
9.1
80
405
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
38.1
9.1
11
*
R01AD11
ATC
triamcinolone; nasal
3.2
9.1
39
136
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
19.5
9.0
13
7
M04AA01
ATC
allopurinol; systemic
3.5
9.0
33
104
R51
ICD-10 Finland
Headache
4.0
9.0
27
74
L04AA13
ATC
[U] leflunomide
9.1
9.0
18
21
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.0
8.9
44
166
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.4
8.9
35
115
L01BA01
ATC
methotrexate; systemic
7.0
8.9
21
32
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
4.2
8.8
24
61
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.3
8.8
94
517
R02
ICPC
Shortness of breath/dyspnoea
3.0
8.8
43
162
M48.0
ICD-10 Finland
Spinal stenosis
3.1
8.7
39
139
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
7.4
8.7
20
29
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
7.4
8.7
20
29
E000001, ,
ATC
2.5
8.7
68
325
UJF92
NOMESCO Finland
Capsular endoscopy
9.5
8.7
17
19
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.6
8.7
30
91
N03AX09
ATC
lamotrigine; oral
3.8
8.6
28
81
G72.9
ICD-10 Finland
Myopathy, unspecified
17.0
8.6
13
8
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.1
8.6
39
140
N05BA04
ATC
oxazepam; oral
2.3
8.6
88
475
K59.0
ICD-10 Finland
Constipation
4.3
8.5
23
58
D64.9
ICD-10 Finland
Anaemia, unspecified
3.5
8.5
31
97
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
8.3
8.5
18
23
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
3.8
8.5
27
77
K92.1
ICD-10 Finland
Melaena
4.9
8.5
19
41
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.0
8.5
41
153
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
3.4
8.5
33
108
A02BA02
ATC
ranitidine; systemic
2.6
8.5
56
247
ZX110
NOMESCO Finland
Intracutaneous
93.0
8.5
9
*
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
4.1
8.5
24
63
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
7.5
8.4
19
27
A02BC03
ATC
lansoprazole; oral
2.3
8.4
87
471
Z50.1
ICD-10 Finland
Other physical therapy
3.8
8.4
26
73
D07AC01
ATC
betamethasone; topical
2.2
8.3
108
640
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.6
8.3
55
243
R75
ICPC
Sinusitis acute/chronic
3.8
8.2
26
74
TPX10
NOMESCO Finland
Implantation of vascular injection port
6.7
8.2
20
32
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.3
8.2
32
105
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.4
8.2
69
341
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
9.4
8.2
16
18
R30.0
ICD-10 Finland
Dysuria
4.4
8.2
21
51
L28
ICPC
Limited function/disability (L)
2.7
8.2
50
212
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
34.5
8.1
10
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.0
8.1
24
65
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.5
8.1
58
266
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.2
8.0
98
565
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.7
8.0
19
43
J01.1
ICD-10 Finland
Acute frontal sinusitis
8.2
8.0
17
22
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
4.9
8.0
18
39
S01AA01
ATC
chloramphenicol; ophthalmic
4.0
8.0
23
61
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
13.6
8.0
13
10
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
8.9
7.9
16
19
N02AC04
ATC
dextropropoxyphene; oral
7.4
7.9
18
26
H65.2
ICD-10 Finland
Chronic serous otitis media
11.3
7.9
14
13
Z3229
NOMESCO Finland
Other healthcare associate professional
3.2
7.9
33
113
XCK00
NOMESCO Finland
Perimetry
4.0
7.8
23
62
U07
ICPC
Urine symptom/complaint other
3.4
7.8
29
92
UDM02
NOMESCO Finland
Sinoscopy
7.8
7.8
17
23
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
4.8
7.8
18
40
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.3
7.8
72
370
R20.2
ICD-10 Finland
Paraesthesia of skin
3.3
7.8
31
103
M01AH01
ATC
celecoxib; oral
2.5
7.8
57
264
N30.0
ICD-10 Finland
Acute cystitis
2.5
7.7
55
251
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
6.5
7.7
19
31
C09CA06
ATC
candesartan; oral
2.3
7.7
71
364
M25.5
ICD-10 Finland
Pain in joint
2.1
7.7
106
639
J30.3
ICD-10 Finland
Other allergic rhinitis
4.3
7.7
20
49
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
3.4
7.6
28
88
TEA00
NOMESCO Finland
Biopsy of lip
25.9
7.6
10
*
ZX121
NOMESCO Finland
Central venous catheter
25.9
7.6
10
*
R4120
NOMESCO Finland
Occupational therapy
3.4
7.6
29
94
A28
ICPC
Limited function/disability NOS
2.8
7.5
40
157
R06AX26
ATC
fexofenadine; oral
3.2
7.5
31
105
J01DA08
ATC
[U] cefaclor
2.7
7.5
43
176
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.6
7.5
50
221
G44.2
ICD-10 Finland
Tension-type headache
2.5
7.5
53
241
ZXA05
NOMESCO Finland
Left side
2.3
7.4
71
369
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
7.2
7.4
17
25
M81.9
ICD-10 Finland
Osteoporosis, unspecified
4.4
7.4
19
46
G47.3
ICD-10 Finland
Sleep apnoea
2.3
7.3
69
356
J01EA01
ATC
trimethoprim; systemic
2.2
7.3
84
470
2790C
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[DEFICIENTIA IMMUNOGLOBULINI ALIA]
+∞
7.3
7
*
SPAT1229
SPAT
Assessment of need for aid
3.6
7.3
25
75
N06AB04
ATC
citalopram; systemic
2.3
7.3
65
328
JN4AD
NOMESCO Finland
Body CT examination
3.1
7.3
32
113
ZXH09, ,
SPAT
6.4
7.2
18
30
R51.81
ICD-10 Finland
Facial pain NOS
6.4
7.2
18
30
WX722
NOMESCO Finland
PEEP
4.3
7.2
19
47
R35
ICD-10 Finland
Polyuria
3.5
7.2
25
76
H02BX01
ATC
methylprednisolone, combinations; systemic
4.6
7.1
17
39
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
5.8
7.1
19
35
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.5
7.0
25
77
XLA10, ,
NOMESCO Finland
4.2
7.0
19
48
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.6
7.0
44
189
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
4.0
7.0
20
53
SBA00
NOMESCO Finland
Microbiological examinations
8.6
6.9
14
17
J11.1
ICD-10 Finland
Influenza with other respiratory manifestations, virus not identified
6.0
6.9
18
32
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
6.0
6.9
18
32
C10AC01
ATC
colestyramine; oral
6.0
6.9
18
32
H65.3
ICD-10 Finland
Chronic mucoid otitis media
6.4
6.9
17
28
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.9
6.9
35
134
S97
ICPC
Chronic ulcer skin
3.6
6.9
23
68
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
9.7
6.9
13
14
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
6.9
80
449
R49.01
ICD-10 Finland
Functional dysphonia
4.1
6.8
19
49
W19
ICD-10 Finland
Unspecified fall
3.0
6.8
32
117
ZXD05
NOMESCO Finland
Urgent procedure
2.1
6.8
92
546
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
17.3
6.8
10
6
318
Kela drug reimbursment
Teriparatide
41.2
6.8
8
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.5
6.8
45
198
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.2
6.8
69
367
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.0
6.7
32
118
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
3.2
6.7
27
90
G50.1
ICD-10 Finland
Atypical facial pain
8.2
6.7
14
18
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
9.1
6.6
13
15
R78
ICPC
Acute bronchitis/bronchiolitis
9.1
6.6
13
15
M01AH02
ATC
rofecoxib; oral
2.6
6.6
40
168
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.6
6.6
42
181
M03BX01
ATC
baclofen; systemic
6.5
6.6
16
26
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
6.5
6.6
16
26
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
6.5
77
433
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.5
6.5
46
208
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
6.5
122
810
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.2
6.5
61
313
C08DA01
ATC
verapamil; systemic
3.9
6.5
19
51
DPA20
NOMESCO Finland
Trephine of frontal sinus
71.6
6.5
7
*
E23.03
ICD-10 Finland
Lack of ACTH
71.6
6.5
7
*
M81.4
ICD-10 Finland
Drug-induced osteoporosis
71.6
6.5
7
*
H02AA02
ATC
fludrocortisone; oral
71.6
6.5
7
*
Z71.8
ICD-10 Finland
Other specified counselling
2.0
6.4
99
613
A10BH01
ATC
sitagliptin; oral
3.1
6.4
28
98
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.6
6.4
22
66
ZXD20
NOMESCO Finland
Day surgery
2.5
6.4
45
203
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
6.2
6.4
16
27
D02AE01
ATC
carbamide; topical
3.3
6.4
25
82
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.1
6.4
27
93
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.1
6.4
27
93
A01
ICPC
Pain general/multiple sites
2.8
6.3
33
128
K07.60
ICD-10 Finland
Snapping jaw
3.2
6.3
26
88
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
5.3
6.3
18
36
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
7.3
6.3
14
20
J96.0
ICD-10 Finland
Acute respiratory failure
18.6
6.3
9
5
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
5.6
6.3
17
32
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.2
6.3
17
43
D84.19
ICD-10 Finland
Unspecified defect in the complement system
+∞
6.3
6
*
D84.1
ICD-10 Finland
Defects in the complement system
+∞
6.3
6
*
J06.80
ICD-10 Finland
Continuously repeating infections of a child
+∞
6.3
6
*
D81.1
ICD-10 Finland
Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
+∞
6.3
6
*
4AA24, ,
NOMESCO Finland
+∞
6.3
6
*
R50.1
ICD-10 Finland
Persistent fever
+∞
6.3
6
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
6.3
59
303
J01DA09
ATC
[U] cefadroxil
2.1
6.2
79
456
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.1
6.2
26
89
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.0
6.2
29
106
C05AA08
ATC
fluocortolone; rectal, topical
2.5
6.2
43
193
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
4.3
6.2
16
39
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.7
6.2
35
142
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.9
6.2
30
112
ZY010
NOMESCO Finland
Hospital outpatient
3.2
6.1
25
84
M05BB03
ATC
alendronic acid and colecalciferol; oral
7.0
6.1
14
21
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
7.0
6.1
14
21
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
7.0
6.1
14
21
WX882
NOMESCO Finland
High dependency care
5.8
6.1
16
29
S01GX05
ATC
lodoxamide; ophthalmic
10.4
6.1
11
11
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
10.4
6.1
11
11
D07AD01
ATC
clobetasol; topical
2.3
6.0
52
257
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.6
6.0
36
150
M05BX04
ATC
denosumab; parenteral
3.5
6.0
21
64
M05BA07
ATC
risedronic acid; oral
7.5
6.0
13
18
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
154
142
25.56
160.42
4.1
1.7
1.06
1.40
g/l
0.82
144
133
66
12
73.66
119.65
2.4
1.8
—
—
—
0
0
64
15
56.48
109.97
1.8
2.0
42.67
30.71
%
1.70
54
15
116
149
13.37
92.83
1.8
1.2
86.94
292.55
u/ml
0.73
106
141
57
20
36.34
87.35
2.0
1.8
430.63
733.20
e6/l
0.79
49
15
174
501
8.66
65.64
4.0
1.4
1.68
2.24
g/l
4.95
148
311
43
23
22.25
55.60
3.6
2.0
—
—
—
0
0
52
44
14.56
53.12
2.5
1.8
—
—
—
0
0
39
20
22.81
51.22
3.8
2.1
—
—
—
0
0
52
48
13.33
50.27
2.5
1.7
—
—
—
0
0
113
277
6.50
47.66
3.5
1.8
—
—
—
0
0
43
32
15.94
47.08
2.7
1.8
—
—
—
0
0
228
1128
10.05
41.69
20.6
5.9
1.92
1.98
e9/l
0.24
228
1013
39
34
13.34
38.73
2.1
1.6
—
—
—
0
0
39
35
12.96
38.02
2.1
1.8
—
—
—
0
0
39
35
12.96
38.02
2.1
1.8
—
—
—
0
0
55
80
8.47
37.66
3.3
1.7
—
—
—
0
0
72
142
6.65
37.19
3.8
1.6
—
—
—
0
0
234
1267
10.46
36.35
25.4
9.6
4.02
3.91
e9/l
0.37
229
1104
32
24
15.09
34.58
3.7
1.1
—
—
—
0
0
43
51
9.92
34.53
3.1
2.8
—
—
—
0
0
85
210
5.55
34.28
3.4
2.0
310.57
364.58
nmol/l
1.40
77
194
32
25
14.48
33.77
3.7
1.1
—
—
—
0
0
31
24
14.55
32.86
2.2
1.7
—
—
—
0
0
33
29
12.91
32.45
2.1
1.7
—
—
—
0
0
34
32
12.09
32.00
4.3
1.5
—
—
—
0
0
34
32
12.09
32.00
4.3
1.5
—
—
—
0
0
34
32
12.09
32.00
4.3
1.5
—
—
—
0
0
33
30
12.47
31.75
4.4
1.6
—
—
—
0
0
33
31
12.07
31.08
4.4
1.5
—
—
—
0
0
33
31
12.07
31.08
4.4
1.5
—
—
—
0
0
30
26
12.93
29.68
2.3
1.7
—
—
—
0
0
74
189
5.09
28.24
2.5
1.7
—
—
—
0
0
45
73
7.26
27.65
4.9
1.8
—
—
—
0
0
32
7
51.93
27.18
1.1
1.0
98.03
98.57
%
—
32
7
37
52
8.14
25.73
4.1
1.4
—
—
—
0
0
43
74
6.78
24.91
4.5
2.1
—
—
—
0
0
70
192
4.64
24.18
2.6
1.7
—
—
—
0
0
81
253
4.21
23.53
3.7
2.3
19.52
23.50
%
1.51
75
220
174
910
3.82
23.19
4.6
2.4
81.49
77.09
nmol/l
1.23
167
818
193
1106
3.99
21.81
9.6
6.2
8.62
10.66
umol/l
3.91
188
1054
175
973
3.50
20.03
16.5
7.1
1.22
1.22
mmol/l
0.37
152
841
46
104
5.17
19.85
2.0
1.3
—
—
—
0
0
163
885
3.30
19.07
16.7
6.6
1.21
1.22
mmol/l
0.99
157
822
44
99
5.16
19.07
2.5
1.7
—
—
—
0
0
28
40
7.73
19.06
6.6
6.9
121.80
519.89
iu/ml
—
5
9
108
462
3.31
18.96
3.8
3.0
683.15
697.27
ng/l
0.03
93
382
30
21
16.00
18.63
2.2
2.1
—
—
—
0
0
30
21
16.00
18.63
2.2
2.1
—
—
—
0
0
30
21
16.00
18.63
2.2
2.1
—
—
—
0
0
27
41
7.24
17.39
2.0
1.4
—
—
—
0
0
234
1651
5.66
17.19
21.3
7.3
78.41
77.95
u/l
0.07
229
1550
23
10
25.10
16.75
2.4
1.9
—
—
—
0
0
33
65
5.68
16.49
1.8
1.3
—
—
—
0
0
33
66
5.59
16.22
1.6
1.1
—
—
—
0
0
25
38
7.18
16.06
1.2
1.3
—
—
—
0
0
32
63
5.66
15.98
1.9
1.9
—
256.00
—
0
5
30
57
5.83
15.54
1.6
1.2
—
—
—
0
0
151
848
2.89
15.50
14.8
9.7
1.06
1.16
inr
1.43
46
265
23
14
17.90
15.08
2.6
2.1
—
—
—
0
0
23
14
17.90
15.08
2.6
2.1
—
—
—
0
0
29
55
5.82
15.04
1.4
1.3
3.30
1.08
u/ml
—
5
5
20
8
26.93
14.93
2.8
2.8
—
—
—
0
0
20
8
26.93
14.93
2.8
2.8
—
—
—
0
0
20
8
26.93
14.93
2.8
2.8
—
—
—
0
0
43
116
4.25
14.78
10.0
4.5
2.38
1.59
mmol/l
0.73
37
82
102
477
2.89
14.63
3.0
1.9
1.35
1.07
mg/l
0.38
81
364
24
19
13.80
14.22
1.4
1.3
0.36
0.54
u/ml
—
14
10
26
26
10.99
13.84
2.5
1.5
—
—
—
0
0
74
302
3.04
13.44
2.3
2.5
205.05
117.34
ug/g
0.58
56
239
29
61
5.23
13.43
1.8
1.5
297.59
274.13
ug/g
0.24
17
33
24
44
5.91
12.85
6.0
3.7
3.61
4.32
e9/l
0.70
24
44
126
694
2.60
12.69
5.6
3.3
24.73
26.61
ng/l
0.09
83
437
21
34
6.64
12.68
1.6
1.5
—
—
—
0
0
24
45
5.78
12.55
8.6
4.2
54.83
55.76
%
0.10
24
45
30
71
4.65
12.10
2.7
1.2
—
—
—
0
0
127
721
2.51
11.76
8.4
3.0
—
—
—
0
0
155
966
2.52
11.70
4.8
2.7
128.41
90.78
ug/l
1.27
150
894
33
87
4.20
11.61
1.7
1.6
—
—
—
0
0
20
17
12.65
11.55
2.8
1.4
—
—
—
0
0
131
761
2.47
11.45
2.6
1.8
96.22
98.23
pmol/l
0.17
72
383
49
181
3.11
10.39
12.2
11.2
1.69
1.44
mmol/l
0.11
41
147
27
67
4.39
10.24
2.7
2.2
1.52
1.52
g/l
0.01
21
59
163
1079
2.40
10.20
8.3
4.6
0.00
0.00
estimate
0.50
36
215
164
1090
2.39
10.15
6.5
3.3
0.00
0.00
estimate
-0.00
36
205
15
9
17.59
10.00
3.3
1.7
—
—
—
0
0
20
40
5.34
9.74
1.4
1.4
—
—
—
0
0
20
40
5.34
9.74
1.4
1.4
—
—
—
0
0
21
44
5.11
9.72
1.7
2.3
—
—
—
0
0
24
57
4.54
9.61
1.4
1.3
—
—
—
0
0
67
305
2.62
9.60
2.1
1.7
1348.94
1170.84
nmol/l
0.82
56
219
14
8
18.40
9.51
3.4
1.5
—
—
—
0
0
160
1077
2.29
9.26
6.5
3.3
0.00
0.00
estimate
0.50
37
226
14
9
16.36
9.14
3.4
1.4
—
—
—
0
0
24
61
4.24
8.82
1.5
1.3
24.02
38.48
u/ml
—
5
8
13
8
17.02
8.64
2.0
1.6
—
—
—
0
0
100
568
2.24
8.63
8.0
2.9
0.33
0.40
e6/l
0.19
88
411
16
17
9.95
8.41
1.7
1.4
—
—
—
0
0
89
488
2.26
8.31
3.4
2.4
—
—
—
0
0
47
192
2.77
8.25
6.3
3.1
—
—
—
0
0
17
21
8.58
8.23
1.2
1.6
—
—
—
0
0
17
21
8.58
8.23
1.2
1.6
—
—
—
0
0
16
18
9.40
8.17
4.8
3.8
—
—
—
0
0
81
431
2.28
8.10
2.1
1.5
23.88
22.21
nmol/l
0.41
70
363
14
13
11.31
7.89
3.5
1.5
—
—
—
0
0
20
34
6.29
7.86
2.2
1.4
—
—
—
0
0
249
2210
5.07
7.56
49.9
12.1
17.61
21.21
mg/l
1.52
232
1700
18
42
4.53
7.34
2.9
2.3
123.30
132.64
g/l
—
10
28
75
405
2.20
7.12
1.5
1.3
13.15
31.88
iu/ml
2.77
22
139
13
13
10.46
7.12
1.8
1.3
—
—
—
0
0
74
401
2.19
6.95
1.3
1.3
4.47
10.01
u/ml
0.78
23
169
10
6
17.25
6.80
1.3
1.3
—
—
—
0
0
17
41
4.37
6.66
1.2
1.2
0.93
3.41
u/ml
—
7
28
13
15
9.06
6.63
1.4
1.1
—
—
—
0
0
86
511
2.03
6.25
3.0
2.7
4083.68
6067.71
umol/l
0.19
79
449
16
28
6.02
6.25
1.1
1.0
5.95
1.25
u/ml
—
10
17
41
181
2.51
6.11
1.8
1.2
33.35
153.93
iu/ml
3.56
19
70
11
11
10.38
6.09
1.3
1.4
—
—
—
0
0
9
6
15.47
5.94
1.3
1.2
—
—
—
0
0
9
6
15.47
5.94
1.3
1.3
—
—
—
0
0
9
6
15.47
5.94
1.3
1.2
—
—
—
0
0
9
6
15.47
5.94
1.3
1.3
—
—
—
0
0
65
355
2.11
5.89
3.8
3.5
155.15
267.58
ng/l
0.36
33
242
17
46
3.89
5.74
1.8
1.2
—
—
—
0
0
17
46
3.89
5.74
1.4
1.5
119.43
111.29
u/ml
—
7
7
92
575
1.93
5.70
7.7
3.4
0.00
0.00
estimate
0.50
36
217
16
42
4.00
5.63
1.8
1.1
68.57
25.43
iu/ml
—
7
7
46
223
2.29
5.57
25.8
7.4
102.17
104.52
mmol/l
1.79
46
223
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
18
52
3.65
5.56
16.9
5.3
0.28
0.35
u/ml
0.60
13
26
20
63
3.36
5.44
1.4
1.5
0.01
0.07
iu/ml
—
5
11
11
14
8.15
5.40
2.5
1.1
—
—
—
0
0
10
11
9.40
5.33
1.4
1.2
—
—
—
0
0
11
15
7.61
5.20
1.0
1.1
—
—
—
0
0
10
12
8.62
5.11
1.6
1.3
1.75
1.94
mmol/l
—
10
12
195
1586
1.95
5.00
5.2
3.4
—
—
—
0
0
17
51
3.50
4.98
1.2
1.6
—
—
—
0
0
136
995
1.78
4.89
4.0
2.6
—
—
—
0
0
14
29
5.04
4.88
1.4
1.1
—
—
—
0
0
9
10
9.27
4.82
1.8
1.5
—
—
—
0
0
9
10
9.27
4.82
1.8
1.5
—
—
—
0
0
9
10
9.27
4.82
1.8
1.5
—
—
—
0
0
9
10
9.27
4.82
1.8
1.5
—
—
—
0
0
8
7
11.74
4.81
4.4
2.6
3.67
6.83
umol/l
—
8
7
14
30
4.87
4.76
1.4
1.1
—
—
—
0
0
234
2051
2.57
4.73
32.0
11.0
87.51
86.34
ml/min/173m2
0.35
218
1658
7
5
14.33
4.60
1.9
3.4
—
—
—
0
0
13
27
5.01
4.56
1.7
1.3
—
—
—
0
0
13
27
5.01
4.56
1.2
1.3
—
—
—
0
0
79
505
1.81
4.40
2.1
1.6
—
—
—
0
0
11
20
5.69
4.34
1.3
1.6
—
—
—
0
0
66
401
1.87
4.31
2.0
1.7
486.84
458.84
pmol/l
0.39
58
335
7
6
11.94
4.30
1.6
1.2
7.57
12.00
u/l
—
7
6
10
17
6.07
4.17
1.1
1.0
—
—
—
0
0
186
1535
1.77
4.01
5.2
3.2
64.49
42.87
u/l
1.36
180
1453
14
43
3.39
3.97
2.2
1.3
38401.56
21990.87
e6/l
—
9
30
202
1713
1.84
3.90
6.5
4.0
14.70
14.60
pmol/l
0.23
190
1571
8
11
7.46
3.89
1.6
1.4
477.00
285.43
u/l
—
8
11
22
90
2.58
3.83
31.0
3.4
0.71
0.67
%
0.17
22
90
21
84
2.63
3.82
3.4
4.5
49.91
50.53
%
0.04
21
84
101
716
1.68
3.81
3.5
3.1
2.34
2.36
mmol/l
0.85
85
637
10
20
5.16
3.72
1.5
1.8
—
—
—
0
0
12
30
4.14
3.64
1.2
1.0
—
—
—
0
0
53
319
1.83
3.52
6.5
2.9
2.80
2.73
e6/l
0.02
32
160
55
336
1.81
3.48
6.4
2.7
0.66
0.84
e6/l
0.40
34
177
113
841
1.61
3.44
7.1
3.3
—
—
—
0
0
11
27
4.21
3.43
1.3
1.0
—
—
—
0
0
39
214
1.97
3.42
3.6
2.5
49.76
27.00
u/l
0.97
34
175
81
557
1.66
3.37
1.4
1.3
0.65
1.43
u/ml
1.31
23
160
10
23
4.48
3.34
1.1
1.2
—
—
—
0
0
6
7
8.74
3.28
1.0
1.0
2917.33
1697.57
miu/ml
—
6
7
9
19
4.87
3.27
1.3
1.2
—
—
—
0
0
7
11
6.51
3.20
1.3
1.1
—
—
—
0
0
7
11
6.51
3.20
1.3
1.1
—
—
—
0
0
10
25
4.12
3.12
1.3
1.2
—
—
—
0
0
10
25
4.12
3.12
1.3
1.2
—
—
—
0
0
10
25
4.12
3.12
1.3
1.2
—
—
—
0
0
10
25
4.12
3.12
1.3
1.2
—
—
—
0
0
10
25
4.12
3.12
1.3
1.2
—
—
—
0
0
6
8
7.64
3.07
1.5
1.4
—
—
—
0
0
7
12
5.96
3.04
1.0
1.0
—
—
—
0
0
5
5
10.16
2.99
1.2
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
13
5.50
2.89
1.4
1.2
—
—
—
0
0
226
2041
1.89
2.84
7.4
4.7
1.75
2.43
mu/l
0.60
220
1894
5
6
8.47
2.76
3.0
4.5
252.40
136.00
%
—
5
6
6
10
6.11
2.71
1.3
1.1
—
—
—
0
0
8
19
4.31
2.70
6.0
2.3
—
—
—
0
0
20
93
2.25
2.69
36.9
5.2
24.75
24.64
mmol/l
0.04
20
93
40
240
1.79
2.68
5.0
4.0
33.12
32.57
%
0.11
34
161
12
41
3.02
2.66
6.1
2.8
4.75
5.01
kpa
0.53
12
41
12
41
3.02
2.66
1.4
1.2
—
—
—
0
0
14
56
2.59
2.58
3.7
4.2
8.50
8.88
kpa
0.46
14
56
6
11
5.55
2.56
2.7
3.0
40566.67
37818.64
ug/l
—
6
11
9
26
3.55
2.50
1.1
1.2
—
—
—
0
0
20
96
2.17
2.50
1.7
2.3
388.45
3054.15
u/l
—
6
35
6
12
5.09
2.41
1.5
1.4
1.77
1.55
g/l
—
6
12
5
8
6.35
2.38
1.2
1.1
—
—
%
—
0
0
16
73
2.27
2.26
1.2
1.2
—
—
—
0
0
53
361
1.59
2.23
3.6
2.4
2.44
2.45
mmol/l
0.40
44
315
16
74
2.24
2.19
1.2
1.1
—
—
—
0
0
14
62
2.33
2.11
2.3
1.6
2.74
5.56
iu/l
—
5
23
5
10
5.07
2.08
1.2
4.9
—
—
—
0
0
80
606
1.46
2.05
1.7
1.7
1.33
1.43
mmol/l
0.50
72
514
6
15
4.07
2.05
2.2
2.0
9.12
10.39
umol/l
—
6
15
45
302
1.59
2.01
2.0
2.0
—
—
—
0
0
7
21
3.40
1.98
1.1
1.2
—
—
—
0
0
5
11
4.61
1.95
1.0
1.3
—
—
—
0
0
6
17
3.59
1.85
1.5
1.7
0.78
1.08
g/l
—
6
17
5
12
4.23
1.83
1.8
1.5
6.40
3.13
mg/l
—
5
12
33
210
1.66
1.82
3.3
4.0
3.95
27.70
ug/l
0.62
25
173
7
25
2.85
1.66
1.0
1.0
—
—
—
0
0
28
176
1.66
1.63
3.0
2.6
70.50
70.63
ml/min/173m2
0.01
12
79
72
558
1.40
1.60
4.2
3.7
20.34
9.07
mg/mmol
0.38
48
343
6
20
3.05
1.59
1.0
3.4
108.67
104.35
%
—
6
20
6
21
2.90
1.51
1.2
1.1
—
—
—
0
0
5
16
3.17
1.44
3.2
3.6
—
—
—
0
0
45
329
1.45
1.37
2.2
2.1
—
—
—
0
0
14
76
1.89
1.32
2.2
1.2
—
—
—
0
0
9
45
2.04
1.24
2.3
2.0
0.91
0.84
nmol/l
—
9
37
15
242
0.60
1.13
1.7
1.6
—
—
—
0
0
8
43
1.89
0.88
3.0
1.6
—
—
—
0
0
208
1969
1.30
0.87
6.6
5.1
38.91
38.94
mmol/mol
0.02
199
1851
218
2093
1.27
0.68
5.1
4.2
5.93
5.80
mmol/l
0.58
206
1950
252
2475
1.93
0.67
62.3
18.2
39.78
40.46
%
1.55
247
2345
5
29
1.74
0.64
2.6
1.4
—
—
—
0
0
8
49
1.65
0.62
1.5
1.2
—
—
—
0
0
19
139
1.40
0.62
1.2
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
13
89
1.49
0.59
1.5
1.5
—
—
—
0
0
17
126
1.37
0.53
1.1
1.0
—
—
—
0
0
54
468
1.19
0.51
1.6
1.4
—
—
—
0
0
7
47
1.50
0.48
1.1
1.1
—
—
—
0
0
23
183
1.28
0.47
2.6
2.0
—
—
—
0
0
214
2073
1.19
0.45
4.1
3.8
1.41
1.26
mmol/l
1.83
203
1935
19
148
1.31
0.45
2.1
1.9
—
—
—
0
0
0
17
0.00
0.41
0.0
1.5
—
—
—
0
0
20
246
0.80
0.39
14.6
5.8
—
—
—
0
0
5
37
1.36
0.37
2.8
2.1
—
—
—
0
0
5
76
0.65
0.36
1.4
1.6
—
—
—
0
0
11
139
0.78
0.27
1.2
1.5
—
—
—
0
0
11
86
1.29
0.26
1.7
1.8
—
—
—
0
0
5
71
0.70
0.26
1.4
1.4
—
—
—
0
0
5
71
0.70
0.26
1.4
1.4
—
—
—
0
0
5
71
0.70
0.26
1.4
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
5
43
1.17
0.21
1.8
1.5
—
—
—
0
0
220
2165
1.11
0.20
4.6
4.2
4.81
4.80
mmol/l
0.04
211
2034
219
2158
1.10
0.18
4.7
4.2
1.56
1.52
mmol/l
0.68
210
2020
6
79
0.75
0.15
1.2
1.7
—
—
—
0
0
221
2194
1.05
0.07
5.0
4.7
2.77
2.87
mmol/l
0.90
211
2056
28
287
0.97
0.01
3.6
4.1
22.15
21.34
%
0.09
15
126
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_DEF_IGG and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_DEF_IGG | 2.525 [1.85, 3.45] | < 0.001 |
| Birth year | 1.0 [0.99, 1.01] | 0.938 |
During the follow-up period (1.1.1998 — 31.12.2019), 72 out of 613 females with D3_DEF_IGG died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have D3_DEF_IGG.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.284% | No data |
| 5 | 1.813% | No data |
| 10 | 4.498% | No data |
| 15 | 8.646% | No data |
| 20 | 14.401% | No data |
Relationships between endpoints
↥Index endpoint: D3_DEF_IGG – Selective deficiency of immunoglobulin G [IgG] subclasses
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data