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Nonhereditary hypogammaglobulinemia

DOID EFO Endpoint Browser PheWeb

D3_NONHEREDHYPOGAMMA

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D80.1
  • Cause of death: ICD-10 — D80.1

2 out of 7 registries used, show all original rules.

394

4. Check minimum number of events

None

394

5. Include endpoints

None

394

6. Filter based on genotype QC (FinnGen only)

381

Control definitions (FinnGen only)

Control exclude
D3_IMMUNEMECHANISM

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D80
Name in latin
Hypogammaglobulinaemia non familialis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1373 825 543
Only index persons 1282 786 496
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.03 0.03 0.02
Median age at first event (years)
Whole population 50.05 52.53 46.32
Only index persons 49.45 52.05 45.35

-FinnGen-

Key figures

All Female Male
Number of individuals 381 251 130
Unadjusted period prevalence (%) 0.08 0.09 0.06
Median age at first event (years) 52.09 50.99 54.22

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
394
Matched controls
3940
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
+∞
307.7
388
*
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
+∞
225.3
194
*
120
Kela drug reimbursment
Hypogammaglobulinaemia
+∞
224.0
193
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
28.6
184.8
138
73
ZX120
NOMESCO Finland
Intravenous
17.4
174.4
185
191
WW200
NOMESCO Finland
Immunization
40.8
149.0
94
30
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
22.2
148.5
122
78
J47
ICD-10 Finland
Bronchiectasis
44.2
137.0
84
24
J01MA12
ATC
levofloxacin; systemic
11.2
132.5
216
386
J01MA14
ATC
moxifloxacin; systemic
13.2
127.2
150
175
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
24.2
124.4
95
51
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
+∞
110.8
101
*
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
25.9
110.5
81
39
J18.9
ICD-10 Finland
Pneumonia, unspecified
8.9
108.3
222
497
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
11.0
101.7
133
175
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
+∞
100.4
92
*
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
+∞
95.8
88
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
11.3
92.3
113
135
TDM10
NOMESCO Finland
Puncture of maxillary antrum
14.5
90.3
90
79
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
14.6
87.2
86
74
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
8.3
85.3
146
261
TPH04
NOMESCO Finland
Cathetrisation of vein
7.0
82.4
202
518
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
11.3
79.9
95
108
H02AB09
ATC
hydrocortisone; systemic
23.8
79.1
59
29
UGC12
NOMESCO Finland
Flexible bronchoscopy
11.5
78.3
91
100
6BA02, ,
NOMESCO Finland
312.7
77.4
76
*
R50.9
ICD-10 Finland
Fever, unspecified
7.2
76.7
154
322
H02AB06
ATC
prednisolone; systemic
8.3
75.6
316
1294
D80.0
ICD-10 Finland
Hereditary hypogammaglobulinaemia
+∞
75.5
70
*
J45.1
ICD-10 Finland
Nonallergic asthma
9.5
74.5
103
142
GD1AA
NOMESCO Finland
Thorax X-ray examination
7.3
74.4
297
1161
A49.9
ICD-10 Finland
Bacterial infection, unspecified
8.6
73.7
112
173
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
6.2
72.4
225
701
TGC00
NOMESCO Finland
Bronchial lavation
20.0
71.0
57
33
H02AB07
ATC
prednisone; oral
6.9
68.8
137
281
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
8.9
66.2
95
136
C01CA24
ATC
epinephrine; parenteral
8.3
63.2
97
150
J32.4
ICD-10 Finland
Chronic pansinusitis
25.9
61.7
44
19
GD1AD
NOMESCO Finland
Thorax CT examination
10.1
60.9
76
91
XW000
NOMESCO Finland
Bone marrow biopsy
12.9
59.4
61
55
J01.0
ICD-10 Finland
Acute maxillary sinusitis
5.0
56.4
206
704
R03BB04
ATC
tiotropium bromide; inhalant
7.5
54.4
90
150
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
5.2
54.1
161
464
L03AA02
ATC
filgrastim; parenteral
12.0
53.9
58
56
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
8.9
53.6
74
100
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
9.8
53.0
67
81
D83.0
ICD-10 Finland
Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
+∞
50.1
47
*
Z01.8
ICD-10 Finland
Other specified special examinations
4.7
48.3
169
547
J45.9
ICD-10 Finland
Asthma, unspecified
4.8
48.0
150
444
D83.9
ICD-10 Finland
Common variable immunodeficiency, unspecified
+∞
47.9
45
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.4
47.5
217
854
J45.0
ICD-10 Finland
Predominantly allergic asthma
6.2
47.4
95
191
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
4.7
45.9
148
447
J01FA06
ATC
roxithromycin; oral
4.4
45.1
255
1158
UDH02
NOMESCO Finland
Rhinopharyngoscopy
6.5
44.3
82
152
J45.8
ICD-10 Finland
Mixed asthma
12.3
43.2
45
41
J46
ICD-10 Finland
Status asthmaticus
12.6
43.0
44
39
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
6.4
42.4
80
151
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
9.4
40.8
52
63
M05BA04
ATC
alendronic acid; oral
6.5
39.1
72
132
J01MA02
ATC
ciprofloxacin; systemic
3.9
38.6
218
959
A07AA02
ATC
nystatin; oral
7.2
38.4
62
99
R03DA04
ATC
theophylline; systemic, rectal
8.9
38.4
51
65
UJF32
NOMESCO Finland
Coloscopy
4.0
38.2
162
587
XG410
NOMESCO Finland
Flow-volume spirometry
10.0
37.6
45
50
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.5
37.3
84
186
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
7.5
37.3
58
89
WW500
NOMESCO Finland
Blood transfusion
9.4
37.2
47
56
JN4BD
NOMESCO Finland
Extensive body CT
5.3
37.0
87
200
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
12.7
36.6
37
32
R03BA02
ATC
budesonide; inhalant
4.1
36.3
135
444
R03DC03
ATC
montelukast; oral
4.2
36.0
127
402
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
4.2
35.8
296
1648
L04AX01
ATC
azathioprine; systemic
8.7
35.7
48
62
R03AK06
ATC
salmeterol and fluticasone; inhalant
4.4
34.5
110
322
R03BB01
ATC
ipratropium bromide; inhalant
9.3
34.1
43
51
J05AB11
ATC
valaciclovir; oral
4.1
33.9
123
395
M36.8*D80.1
ICD-10 Finland
Systemic disorders of connective tissue in hypogammaglobulinaemia
+∞
33.8
32
*
UJF30
NOMESCO Finland
Ileoscopy through colon
4.9
33.4
85
208
J01FF01
ATC
clindamycin; systemic
3.6
32.9
174
717
WZC30
NOMESCO Finland
Teaching
4.1
32.9
114
354
A41.9
ICD-10 Finland
Sepsis, unspecified
10.0
32.7
39
43
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.2
32.2
76
174
J01FA15
ATC
telithromycin; oral
4.6
32.2
90
237
ZXA10
NOMESCO Finland
Bilateral
3.9
32.1
121
398
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
3.5
31.9
173
722
JN4AD
NOMESCO Finland
Body CT examination
5.1
31.8
76
176
C03CA01
ATC
furosemide; systemic
3.6
30.9
143
538
M04AA01
ATC
allopurinol; systemic
4.8
30.5
80
200
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
9.2
30.1
38
45
R03AK08
ATC
formoterol and beclometasone; inhalant
6.9
29.9
49
79
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
5.9
28.9
56
107
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.0
28.5
98
300
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
9.7
28.1
34
38
R03AC12
ATC
salmeterol; inhalant
6.9
28.1
46
74
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
10.2
27.4
32
34
WE300
NOMESCO Finland
Profylactive therapy of malignancy with biomoidiers
+∞
27.4
26
*
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
64.7
26.4
30
5
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
35.9
26.0
33
10
R01AD08
ATC
fluticasone; nasal
3.1
25.7
173
800
R03AC02
ATC
salbutamol; inhalant
3.3
25.5
281
1706
J01FA10
ATC
azithromycin; systemic
3.5
25.1
305
1951
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
8.7
25.1
33
41
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
3.1
25.1
268
1592
SPAT1262
SPAT
Handing over of treatment supplies
3.6
25.1
104
359
TPX10
NOMESCO Finland
Implantation of vascular injection port
8.4
25.0
34
44
JN3AD
NOMESCO Finland
Abdominal CT examination
4.2
25.0
77
216
Z3231
NOMESCO Finland
Registered nurse
3.1
24.9
160
719
A46
ICD-10 Finland
Erysipelas
3.8
24.1
89
284
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.7
23.9
61
148
H02AB04
ATC
methylprednisolone; systemic
3.6
23.9
94
313
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
8.9
23.4
30
36
J02AC01
ATC
fluconazole; systemic
2.8
22.8
217
1190
R03AC13
ATC
formoterol; inhalant
5.7
22.8
45
87
R01AD05
ATC
budesonide; nasal
4.5
22.6
60
150
R03BA08
ATC
ciclesonide; inhalant
4.1
22.6
70
197
A03FA01
ATC
metoclopramide; systemic, rectal
3.0
22.3
137
594
J01FA09
ATC
clarithromycin; systemic
2.8
22.1
180
907
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
26.9
22.1
30
12
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.9
22.0
53
122
ZYC01
NOMESCO Finland
Remote contact by phone
4.7
22.0
55
131
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.2
21.9
114
449
R81
ICPC
Pneumonia
6.7
21.9
36
58
N17.9
ICD-10 Finland
Acute renal failure, unspecified
7.7
21.5
31
43
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.0
21.5
50
112
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
36.1
21.4
27
8
R01AD09
ATC
mometasone; nasal
2.8
21.4
241
1425
N02AA05
ATC
oxycodone; systemic
3.4
21.3
95
341
D83.8
ICD-10 Finland
Other common variable immunodeficiencies
+∞
21.0
20
*
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
44.4
20.7
25
6
ZX108
NOMESCO Finland
Inhalation
44.4
20.7
25
6
J01DA08
ATC
[U] cefaclor
3.7
20.6
76
241
R03BA05
ATC
fluticasone; inhalant
3.0
20.5
114
465
R06AE07
ATC
cetirizine; oral
2.7
20.4
228
1331
A07AA09
ATC
vancomycin; oral
28.8
20.3
27
10
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.7
20.3
75
238
D80.2
ICD-10 Finland
Selective deficiency of immunoglobulin A [IgA]
+∞
20.0
19
*
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.4
19.9
85
296
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
7.3
19.8
30
44
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
7.9
19.8
28
38
H04.10
ICD-10 Finland
Dry eye syndrome
3.5
19.8
80
269
SPAT1255
SPAT
Intravenous administration of medicine
5.1
19.7
44
95
J01AA02
ATC
doxycycline; systemic
4.0
19.7
347
2559
N02AX02
ATC
tramadol; systemic, rectal
2.6
19.6
208
1177
A04AA01
ATC
ondansetron; systemic, rectal
4.1
19.5
59
162
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
19.4
19.4
29
16
A01AB09
ATC
miconazole; local oral
4.0
19.4
60
168
TAB00
NOMESCO Finland
Lumbar puncture
4.9
19.2
45
101
ZXD05
NOMESCO Finland
Urgent procedure
2.7
18.9
157
786
J01DA06
ATC
[U] cefuroxime
3.1
18.8
95
365
WX892
NOMESCO Finland
Monitored bed care
4.3
18.7
52
134
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
5.7
18.6
36
68
J31.0
ICD-10 Finland
Chronic rhinitis
3.7
18.6
66
203
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
7.0
18.6
29
44
A02BC02
ATC
pantoprazole; systemic
2.9
18.4
300
2067
A01AB04
ATC
amphotericin B; local oral
5.4
18.2
38
77
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
6.2
18.2
32
55
R03AC03
ATC
terbutaline; inhalant
3.2
18.2
83
300
D64.9
ICD-10 Finland
Anaemia, unspecified
4.0
18.1
57
161
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
7.1
18.1
28
42
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
28.3
18.0
24
9
D84.18
ICD-10 Finland
Other specified defect in the complement system
+∞
17.8
17
*
D83.1
ICD-10 Finland
Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
+∞
17.8
17
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.2
17.7
80
287
D70.89
ICD-10 Finland
Neutropenic splenomegaly
22.1
17.5
25
12
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
52.5
17.1
20
*
R06.0
ICD-10 Finland
Dyspnoea
2.6
17.0
131
626
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
16.0
16.9
27
18
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
66.3
16.9
19
*
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
21.2
16.6
24
12
GD1DG
NOMESCO Finland
Extremely extensive MRI examination of pleura with high field magnet
177.2
16.6
17
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
24.3
16.6
23
10
ZX121
NOMESCO Finland
Central venous catheter
42.0
16.5
20
5
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
5.8
16.5
31
57
L04AX03
ATC
methotrexate; systemic
3.4
16.4
65
214
XF400
NOMESCO Finland
ECG with 12 standard connections
3.0
16.3
83
318
R03AK11
ATC
formoterol and fluticasone; inhalant
7.1
16.3
25
37
R4110
NOMESCO Finland
Physiotherapy
2.5
15.8
142
727
Z3226
NOMESCO Finland
Physiotherapist
2.7
15.8
102
445
D84.9
ICD-10 Finland
Immunodeficiency, unspecified
+∞
15.7
15
*
D80.6
ICD-10 Finland
Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
+∞
15.7
15
*
R03AK07
ATC
formoterol and budesonide; inhalant
2.6
15.6
112
514
Z2221
NOMESCO Finland
Medical doctor
2.5
15.5
142
732
JN6AD
NOMESCO Finland
CT of torso and neck
13.8
15.4
26
20
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
18.7
15.3
23
13
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
6.0
15.3
28
50
R05
ICD-10 Finland
Cough
2.6
15.2
112
520
J01.1
ICD-10 Finland
Acute frontal sinusitis
7.1
15.0
23
34
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
17.4
14.9
23
14
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
19.3
14.9
22
12
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.4
14.8
39
96
A07EA06
ATC
budesonide; oral, local oral
4.8
14.8
35
79
L04AA06
ATC
mycophenolic acid; systemic
12.6
14.8
26
22
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
83.3
14.7
16
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.3
14.6
62
213
WZC00
NOMESCO Finland
Treatment plan or consultation
2.3
14.6
173
994
GD1CG
NOMESCO Finland
Extensive examination of lungs and pleura with high intensity magnet
155.5
14.6
15
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.9
14.5
78
307
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
17.8
14.5
22
13
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.8
14.4
83
339
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.6
14.4
36
85
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
28.4
14.4
19
7
A02BC05
ATC
esomeprazole; systemic
2.3
14.4
193
1167
XQ800
NOMESCO Finland
Prick test
3.5
14.3
53
167
UDM02
NOMESCO Finland
Sinoscopy
6.7
14.3
23
36
L01BA01
ATC
methotrexate; systemic
5.7
14.2
27
50
UJF92
NOMESCO Finland
Capsular endoscopy
7.0
14.2
22
33
H65.3
ICD-10 Finland
Chronic mucoid otitis media
6.3
14.0
24
40
WVA20
NOMESCO Finland
Medicine administration
5.9
14.0
26
47
B29
ICPC
Lymph/immune mech sympt/complt other
31.3
14.0
18
6
L03AA13
ATC
pegfilgrastim; parenteral
4.1
14.0
40
105
P01BA02
ATC
hydroxychloroquine; oral
3.3
13.9
57
191
D70.82
ICD-10 Finland
Drug-induced neutropenia
6.8
13.8
22
34
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.0
13.8
69
261
C10AC01
ATC
colestyramine; oral
5.7
13.7
26
48
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.8
13.7
82
342
J06BA02
ATC
immunoglobulins, normal human, for intravascular adm.; systemic
+∞
13.6
13
*
D86.0
ICD-10 Finland
Sarcoidosis of lung
+∞
13.6
13
*
J45
ICD-10 Finland
Asthma
3.2
13.6
59
205
P01AB01
ATC
metronidazole; oral, rectal
2.2
13.5
194
1197
R03DC01
ATC
zafirlukast; oral
11.0
13.4
25
24
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
5.6
13.4
26
49
ZX112
NOMESCO Finland
Subcutaneous
5.7
13.2
25
46
R06AE09
ATC
levocetirizine; oral
2.7
13.2
82
348
R01AD12
ATC
fluticasone furoate; nasal
2.2
13.2
158
904
TQW99
NOMESCO Finland
Other minor procedure on skin
4.3
13.1
35
87
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
19.9
13.0
19
10
B99
ICPC
Blood/lymph/spleen disease other
51.8
12.9
15
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.6
12.8
87
385
A41.8
ICD-10 Finland
Other specified sepsis
11.6
12.7
23
21
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
4.2
12.6
35
90
A28
ICPC
Limited function/disability NOS
2.9
12.5
68
268
ZXA00
NOMESCO Finland
Right side
2.3
12.5
126
667
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
10.1
12.4
24
25
N03AX12
ATC
[U] gabapentin; oral
2.5
12.4
91
418
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
5.2
12.3
26
53
J01DA01
ATC
[U] cefalexin
2.2
12.3
270
1942
A02BC01
ATC
omeprazole; systemic
2.3
12.3
126
672
XG466
NOMESCO Finland
Sleep oxymetry
5.8
12.3
23
42
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
5.8
12.3
23
42
N03AX16
ATC
[U] pregabalin
2.3
12.2
115
591
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.9
12.2
62
236
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.6
12.2
30
70
I50.9
ICD-10 Finland
Heart failure, unspecified
3.2
12.1
52
179
J96.0
ICD-10 Finland
Acute respiratory failure
27.7
12.1
16
6
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.1
12.1
185
1156
J01DB01
ATC
cefalexin; oral
3.1
12.0
350
2839
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.5
12.0
43
132
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.0
12.0
60
226
M05BX04
ATC
denosumab; parenteral
4.0
11.8
35
94
XG474
NOMESCO Finland
Exhalation nntrogen oxide
4.8
11.8
27
59
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.4
11.8
45
144
B01AB05
ATC
enoxaparin; parenteral
2.2
11.8
139
783
ZXA05
NOMESCO Finland
Left side
2.3
11.8
114
592
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
11.7
126
683
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
31.1
11.7
15
5
L01BB05
ATC
fludarabine; systemic
67.0
11.7
13
*
C82.1
ICD-10 Finland
Follicular lymphoma grade II
23.7
11.7
16
7
1XC02, ,
NOMESCO Finland
23.7
11.7
16
7
H65.2
ICD-10 Finland
Chronic serous otitis media
10.5
11.6
22
22
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
5.3
11.6
24
48
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.0
11.6
55
201
C03DA01
ATC
spironolactone; oral
3.0
11.6
56
207
D86.2
ICD-10 Finland
Sarcoidosis of lung with sarcoidosis of lymph nodes
+∞
11.5
11
*
OAB50, ,
SPAT
4.0
11.4
33
87
J20
ICD-10 Finland
Acute bronchitis
2.9
11.4
60
232
A02BA03
ATC
famotidine; systemic
5.4
11.4
23
45
R03BA01
ATC
beclometasone; inhalant
2.6
11.4
74
320
E0000UV, ,
ATC
2.1
11.4
187
1193
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
4.0
11.3
33
88
ZXH06, ,
SPAT
3.8
11.2
35
98
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.3
11.1
105
539
ZXE00
NOMESCO Finland
One hour or less
2.1
11.0
174
1090
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
3.3
11.0
44
145
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
11.0
76
338
WX002
NOMESCO Finland
Sedation and analgesia
2.4
10.9
88
420
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
16.1
10.9
17
11
Z2446
NOMESCO Finland
Social worker
3.3
10.8
42
136
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.8
10.8
60
239
5BA08, ,
NOMESCO Finland
28.9
10.8
14
5
A06AD11
ATC
lactulose; oral
2.7
10.7
63
258
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.3
10.7
98
494
R03AK03
ATC
[U] fenoterol and ipratropium bromide
4.5
10.7
27
64
390
Kela drug reimbursment
Ibrutinib
61.7
10.7
12
*
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
61.7
10.7
12
*
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
61.7
10.7
12
*
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
11.7
10.7
19
17
ZX100
NOMESCO Finland
Oral
11.7
10.7
19
17
K90.0
ICD-10 Finland
Coeliac disease
5.0
10.6
23
48
J05AB01
ATC
aciclovir; systemic
2.2
10.6
110
585
L01XE27
ATC
[U] ibrutinib
112.9
10.5
11
*
D81.0
ICD-10 Finland
Severe combined immunodeficiency [SCID] with reticular dysgenesis
+∞
10.5
10
*
R13
ICD-10 Finland
Dysphagia
3.4
10.5
39
123
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.8
10.4
55
213
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.0
10.4
30
79
N05CF01
ATC
zopiclone; oral
2.1
10.4
144
855
ZX114
NOMESCO Finland
Intramuscular
9.2
10.4
21
24
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
33.5
10.4
13
*
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
33.5
10.4
13
*
N05CD07
ATC
temazepam; oral
2.8
10.3
54
208
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.3
10.3
27
66
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.4
10.3
39
124
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.8
10.3
32
89
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
24.1
10.3
14
6
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
24.1
10.3
14
6
L04AA01
ATC
[U] ciclosporin
13.6
10.2
17
13
A10AB05
ATC
insulin aspart; parenteral
3.2
10.2
43
146
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.9
10.2
50
186
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.7
10.2
62
259
WX872
NOMESCO Finland
Intensive care
4.0
10.1
29
76
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
3.9
10.1
30
81
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.8
10.1
56
223
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.3
10.1
26
63
A03
ICPC
Fever
2.3
10.0
88
435
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.1
10.0
28
72
K59.1
ICD-10 Finland
Functional diarrhoea
3.6
10.0
34
101
B99
ICD-10 Finland
Other and unspecified infectious diseases
8.5
10.0
21
26
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
12.6
9.9
17
14
R04.2
ICD-10 Finland
Haemoptysis
5.3
9.9
20
39
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
4.7
9.9
23
51
ZXH09, ,
SPAT
5.1
9.9
21
43
UDC00
NOMESCO Finland
Ear microscopy
3.1
9.9
43
149
PJA10
NOMESCO Finland
Exploration of lymph nodes
11.0
9.9
18
17
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
20.7
9.9
14
7
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
8.2
9.7
21
27
A02BA02
ATC
ranitidine; systemic
2.3
9.7
84
412
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.8
9.7
51
197
1512
Kela drug reimbursment
Ibrutinib
56.4
9.7
11
*
ZYC01, ,
SPAT
2.8
9.7
53
209
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.6
9.7
23
52
J01CA04
ATC
amoxicillin; systemic
2.6
9.7
343
2841
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.5
9.6
67
298
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.1
9.6
108
591
A02BC03
ATC
lansoprazole; oral
2.1
9.6
126
731
WX882
NOMESCO Finland
High dependency care
7.9
9.5
21
28
R96
ICPC
Asthma
2.8
9.5
50
193
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
9.5
161
1022
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
18.1
9.5
14
8
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
102.4
9.5
10
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.3
9.5
19
37
X57
ICD-10 Finland
Unspecified privation
5.3
9.5
19
37
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
30.8
9.5
12
*
A10AC01
ATC
insulin (human); parenteral
3.1
9.4
41
142
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
9.4
115
648
D73.1
ICD-10 Finland
Hypersplenism
+∞
9.4
9
*
D84.1
ICD-10 Finland
Defects in the complement system
+∞
9.4
9
*
D81.1
ICD-10 Finland
Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
+∞
9.4
9
*
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
4.9
9.4
21
45
N05BA01
ATC
diazepam; systemic, rectal
2.5
9.4
66
295
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
9.9
9.4
18
19
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.8
9.3
50
195
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.3
9.3
36
116
Z3229
NOMESCO Finland
Other healthcare associate professional
3.0
9.3
44
160
J01CF05
ATC
flucloxacillin; systemic
3.2
9.2
37
122
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.1
9.2
39
133
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
9.2
185
1240
R1250
NOMESCO Finland
Evaluation of functional capability
5.0
9.2
20
42
A07EC01
ATC
sulfasalazine; oral, rectal
3.0
9.1
43
156
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.7
9.1
29
82
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
3.0
9.1
41
145
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
9.1
142
873
L28
ICPC
Limited function/disability (L)
2.4
9.1
71
333
ZX110
NOMESCO Finland
Intracutaneous
37.6
9.1
11
*
M81.4
ICD-10 Finland
Drug-induced osteoporosis
37.6
9.1
11
*
S01GX01
ATC
cromoglicic acid; ophthalmic
2.1
9.0
100
542
S97
ICPC
Chronic ulcer skin
3.4
9.0
34
108
J32.2
ICD-10 Finland
Chronic ethmoidal sinusitis
19.1
9.0
13
7
J32.8
ICD-10 Finland
Other chronic sinusitis
19.1
9.0
13
7
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
19.1
9.0
13
7
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.8
9.0
47
181
J05AH02
ATC
oseltamivir; oral
24.7
9.0
12
5
318
Kela drug reimbursment
Teriparatide
24.7
9.0
12
5
ZY010
NOMESCO Finland
Hospital outpatient
3.2
9.0
36
119
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
8.9
155
988
J01DC02
ATC
cefuroxime; systemic
3.3
8.9
34
109
J01.4
ICD-10 Finland
Acute pansinusitis
11.1
8.9
16
15
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
3.1
8.8
38
131
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
4.1
8.7
24
61
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
4.6
8.7
21
48
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
51.1
8.7
10
*
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
7.2
8.7
20
29
E87.6
ICD-10 Finland
Hypokalaemia
4.2
8.6
23
57
B34.9
ICD-10 Finland
Viral infection, unspecified
4.3
8.6
22
53
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
8.6
83
426
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
7.6
8.5
19
26
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
20.6
8.5
12
6
E000006, ,
ATC
3.0
8.5
38
134
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
7.0
8.5
20
30
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
7.0
8.5
20
30
N06AA09
ATC
amitriptyline; systemic
2.6
8.5
50
205
J01FA01
ATC
erythromycin; systemic
2.4
8.5
65
302
Z71.8
ICD-10 Finland
Other specified counselling
1.9
8.5
140
874
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.1
8.5
23
58
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
+∞
8.4
8
*
2790C
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[DEFICIENTIA IMMUNOGLOBULINI ALIA]
+∞
8.4
8
*
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
9.8
8.4
16
17
R05
ICPC
Cough
2.0
8.3
115
675
A04AA02
ATC
granisetron; systemic, transdermal
3.0
8.3
38
136
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
14.9
8.3
13
9
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
4.7
8.2
19
42
N03AX11
ATC
topiramate; oral
4.2
8.2
22
55
R60.0
ICD-10 Finland
Localized oedema
2.5
8.1
53
228
R01AD58
ATC
fluticasone, combinations; nasal
2.0
8.1
115
679
J15.8
ICD-10 Finland
Other bacterial pneumonia
17.6
8.1
12
7
M05BA07
ATC
risedronic acid; oral
6.5
8.1
20
32
K90.9
ICD-10 Finland
Intestinal malabsorption, unspecified
34.1
8.1
10
*
C82.01
ICD-10 Finland
Follicular nodular lymphoma, grade I
34.1
8.1
10
*
J01.9
ICD-10 Finland
Acute sinusitis, unspecified
3.5
8.1
28
84
B28
ICPC
Limited function/disability (B)
22.6
8.1
11
5
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
22.6
8.1
11
5
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.7
8.0
25
70
S01AA01
ATC
chloramphenicol; ophthalmic
3.4
8.0
29
90
E86
ICD-10 Finland
Volume depletion
8.0
8.0
17
22
JAH00
NOMESCO Finland
Laparotomy
4.8
8.0
18
39
I50.0
ICD-10 Finland
Congestive heart failure
3.5
8.0
28
85
R01AD01
ATC
beclometasone; nasal
2.2
8.0
75
380
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
6.3
8.0
20
33
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.2
7.9
74
373
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.2
7.9
32
106
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
4.2
7.9
21
52
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.8
7.9
42
163
XA800
NOMESCO Finland
Neuropsychological investigation
3.2
7.9
31
101
N30.0
ICD-10 Finland
Acute cystitis
2.2
7.9
70
346
R01AC01
ATC
cromoglicic acid; nasal
3.5
7.8
27
81
J01
ICD-10 Finland
Acute sinusitis
3.1
7.8
34
118
WVA20, ,
SPAT
4.5
7.8
19
44
3AC01, ,
NOMESCO Finland
15.4
7.8
12
8
UGC02
NOMESCO Finland
Rigid bronchoscopy
45.9
7.7
9
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.7
7.7
42
165
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
8.3
7.7
16
20
H05AA02
ATC
teriparatide; parenteral
18.8
7.6
11
6
L01AA01
ATC
cyclophosphamide; systemic
18.8
7.6
11
6
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.2
7.6
30
98
J18.1
ICD-10 Finland
Lobar pneumonia, unspecified
10.3
7.6
14
14
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
7.4
7.6
17
24
L04AD01
ATC
ciclosporin; systemic
7.4
7.6
17
24
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
4.4
7.6
19
45
M13.9
ICD-10 Finland
Arthritis, unspecified
2.7
7.5
41
161
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
6.7
7.5
18
28
R75
ICPC
Sinusitis acute/chronic
3.0
7.5
34
121
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
6.2
7.5
19
32
J01MA01
ATC
ofloxacin; systemic
2.8
7.5
39
150
M35.7
ICD-10 Finland
Hypermobility syndrome
7.9
7.5
16
21
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.4
7.5
52
231
L01AA02
ATC
chlorambucil; oral
81.6
7.4
8
*
N03AE01
ATC
clonazepam; systemic
3.1
7.4
31
105
D50.8
ICD-10 Finland
Other iron deficiency anaemias
9.6
7.3
14
15
D84.19
ICD-10 Finland
Unspecified defect in the complement system
+∞
7.3
7
*
R50.0
ICD-10 Finland
Fever with chills
+∞
7.3
7
*
132
Kela drug reimbursment
Sarcoidosis
+∞
7.3
7
*
4AA24, ,
NOMESCO Finland
+∞
7.3
7
*
3XA02, ,
NOMESCO Finland
+∞
7.3
7
*
D86.1
ICD-10 Finland
Sarcoidosis of lymph nodes
+∞
7.3
7
*
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
+∞
7.3
7
*
D80.5
ICD-10 Finland
Immunodeficiency with increased immunoglobulin M [IgM]
+∞
7.3
7
*
J01XB01
ATC
colistin; inhalant, parenteral
+∞
7.3
7
*
N02BF01
ATC
gabapentin; oral
2.6
7.3
42
170
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
16.1
7.3
11
7
TK800
NOMESCO Finland
Hemodialysis
7.5
7.3
16
22
XCK00
NOMESCO Finland
Perimetry
3.1
7.2
30
101
R04
ICPC
Breathing problem other
3.5
7.2
25
75
D07AB08
ATC
desonide; topical
2.4
7.2
55
254
H66.9
ICD-10 Finland
Otitis media, unspecified
2.8
7.2
36
135
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
7.2
66
330
R01BA52
ATC
pseudoephedrine, combinations; oral
1.8
7.2
136
878
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.4
7.2
50
222
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
20.5
7.2
10
5
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
5.8
7.2
19
34
A06AC51
ATC
ispaghula, combinations; oral
3.3
7.1
27
86
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.8
7.1
22
61
WX730
NOMESCO Finland
Conventional respirator
12.3
7.1
12
10
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.6
7.1
23
66
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
4.0
7.1
20
52
R06AX22
ATC
ebastine; oral
2.0
7.1
82
449
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.9
7.1
34
125
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.5
7.0
48
211
H53.1
ICD-10 Finland
Subjective visual disturbances
2.8
7.0
36
137
X58
ICD-10 Finland
Exposure to other specified factors
2.2
7.0
68
348
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.0
7.0
96
558
212
Kela drug reimbursment
Gout
7.7
7.0
15
20
A49.8
ICD-10 Finland
Other bacterial infections of unspecified site
14.1
6.9
11
8
M01CB01
ATC
sodium aurothiomalate; parenteral
14.1
6.9
11
8
4222
FHL
Endonasal etmoidectomy
14.1
6.9
11
8
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
14.1
6.9
11
8
EBA10
NOMESCO Finland
Operative extraction of tooth
2.2
6.9
63
314
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.9
6.9
20
53
J11.1
ICD-10 Finland
Influenza with other respiratory manifestations, virus not identified
4.2
6.9
18
44
B03XA02
ATC
darbepoetin alfa; parenteral
6.9
6.9
16
24
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
6.9
6.9
16
24
DPA25
NOMESCO Finland
Trephine of frontal sinus through nose
8.5
6.9
14
17
R05CA10
ATC
expectorants - combinations
5.8
6.8
18
32
R05CB01
ATC
acetylcysteine; inhalant, oral
11.2
6.8
12
11
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
11.2
6.8
12
11
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
11.2
6.8
12
11
B07.9
ICD-10 Finland
Verruca simplex
3.6
6.8
22
63
R06.2
ICD-10 Finland
Wheezing
3.4
6.8
24
73
DPA20
NOMESCO Finland
Trephine of frontal sinus
40.8
6.8
8
*
GD1BG
NOMESCO Finland
MRI of lungs and pleura with high intensity magnet
40.8
6.8
8
*
E23.03
ICD-10 Finland
Lack of ACTH
40.8
6.8
8
*
J12.1
ICD-10 Finland
Respiratory syncytial virus pneumonia
17.1
6.8
10
6
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.8
6.8
35
134
N06AX21
ATC
duloxetine; oral
2.2
6.8
60
296
R33
ICD-10 Finland
Retention of urine
3.1
6.7
29
100
ZXD20
NOMESCO Finland
Day surgery
2.2
6.7
62
311
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.3
6.7
53
249
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
5.7
6.7
18
33
R49.01
ICD-10 Finland
Functional dysphonia
3.7
6.7
21
59
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.4
6.7
24
74
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.7
6.7
37
147
R03BC03
ATC
nedocromil; inhalant
2.7
6.7
36
141
N17.8
ICD-10 Finland
Other acute renal failure
12.5
6.6
11
9
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
12.5
6.6
11
9
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
12.5
6.6
11
9
JN4CD
NOMESCO Finland
Very extensive body CT
3.9
6.6
19
50
J01DA09
ATC
[U] cefadroxil
1.8
6.6
114
713
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
7.0
6.6
15
22
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
2.2
6.5
55
265
J33.8
ICD-10 Finland
Other polyp of sinus
5.5
6.5
18
34
M01AE03
ATC
ketoprofen; systemic, rectal
1.8
6.5
146
987
N02BE01
ATC
paracetamol; systemic, rectal
2.4
6.5
355
3121
372
Kela drug reimbursment
Idelalisib
71.0
6.4
7
*
J20.6
ICD-10 Finland
Acute bronchitis due to rhinovirus
71.0
6.4
7
*
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
71.0
6.4
7
*
B01.9
ICD-10 Finland
Varicella without complication
71.0
6.4
7
*
C83.00
ICD-10 Finland
Lymphocytic lymphoma
71.0
6.4
7
*
K90.8
ICD-10 Finland
Other intestinal malabsorption
71.0
6.4
7
*
D59.9
ICD-10 Finland
Acquired haemolytic anaemia, unspecified
71.0
6.4
7
*
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
71.0
6.4
7
*
SPAT1229
SPAT
Assessment of need for aid
2.9
6.4
31
114
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.9
6.4
19
51
AA1AD
NOMESCO Finland
CT of head and brain
1.9
6.4
100
604
L04AA13
ATC
[U] leflunomide
5.3
6.4
18
35
L04AD02
ATC
tacrolimus; systemic
11.3
6.3
11
10
WX725
NOMESCO Finland
Noninvasive ventilation
2.9
6.3
29
104
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
18.4
6.3
9
5
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
18.4
6.3
9
5
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
18.4
6.3
9
5
C83.1
ICD-10 Finland
Mantle cell lymphoma
18.4
6.3
9
5
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
7.2
6.3
14
20
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
7.2
6.3
14
20
27510
ICD-8 Finland
Plasma protein abnormalities, Hypogammaglobulinaemia
+∞
6.3
6
*
2790A
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[AGAMMAGLOBULINAEMIA (BRUTON)]
+∞
6.3
6
*
JN5JR
NOMESCO Finland
Extensive PET-CT of upper body metabolism (eyebrows to thighs)
+∞
6.3
6
*
2790B
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[DEFICIENTIA IMMUNOGLOBULINI A]
+∞
6.3
6
*
2790D
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[COMMON VARIABLE HYPOGAMMAGLOBULINEMIA]
+∞
6.3
6
*
D81.9
ICD-10 Finland
Combined immunodeficiency, unspecified
+∞
6.3
6
*
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
6.3
6
*
D84.8
ICD-10 Finland
Other specified immunodeficiencies
+∞
6.3
6
*
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
27.1
6.2
8
*
H25.1
ICD-10 Finland
Senile nuclear cataract
1.9
6.2
86
499
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.5
6.2
21
62
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.6
6.2
35
140
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.5
6.2
40
171
R01BA51
ATC
phenylpropanolamine, combinations; oral
2.2
6.2
55
271
A01
ICPC
Pain general/multiple sites
2.4
6.2
44
197
UJD02
NOMESCO Finland
Gastroscopy
3.1
6.2
25
83
J00
ICD-10 Finland
Acute nasopharyngitis [common cold]
4.2
6.1
16
39
SPAT1254
SPAT
Administration of medicine
2.1
6.1
58
293
NF1AA
NOMESCO Finland
Hip X-ray examination
2.6
6.1
36
147
WVA30, ,
SPAT
3.1
6.1
26
89
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
6.1
150
1036
J02AC02
ATC
itraconazole; systemic
1.9
6.1
80
456
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.4
6.1
22
68
J32.1
ICD-10 Finland
Chronic frontal sinusitis
8.8
6.1
12
14
B01AB04
ATC
dalteparin; parenteral
3.1
6.1
25
84
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
10.2
6.1
11
11
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
5.7
6.1
16
29
ZZR00
NOMESCO Finland
Flap of skin
6.2
6.1
15
25
RD210, ,
NOMESCO Finland
6.2
6.1
15
25
J01DC04
ATC
cefaclor; oral
6.2
6.1
15
25
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.6
6.0
34
136
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.9
6.0
28
101

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
277
214
41.22
307.65
5.0
1.6
1.02
1.50
g/l
1.26
243
199
158
26
100.78
297.19
2.6
1.5
1.20
1.44
e9/l
0.53
143
20
117
22
75.22
212.26
2.2
1.5
38.84
36.66
%
0.24
102
22
112
23
67.64
199.37
2.7
1.5
534.70
741.29
e6/l
0.59
96
17
111
22
69.85
198.95
2.8
1.5
0.23
0.19
e9/l
0.40
97
17
109
28
53.43
184.25
2.3
1.4
—
—
—
0
0
108
28
52.76
182.08
2.3
1.4
1.60
2.93
g/l
2.14
83
18
107
28
52.09
179.92
2.3
1.4
4.27
7.01
g/l
4.26
83
19
107
28
52.09
179.92
2.3
1.4
0.22
0.34
g/l
1.56
84
19
114
49
32.33
164.64
2.3
2.0
0.21
0.80
g/l
1.61
90
40
90
16
72.61
163.60
3.1
1.4
13.82
11.81
u/l
0.67
90
16
94
40
30.55
135.29
4.6
2.6
—
—
—
0
0
287
728
11.83
129.00
4.9
1.4
1.30
2.34
g/l
16.56
223
454
149
215
10.54
106.40
1.9
1.2
62.20
256.21
u/ml
1.09
109
198
66
23
34.27
100.77
2.6
2.4
42.59
43.45
%
0.07
49
11
361
1516
17.49
90.42
26.0
6.1
—
—
—
0
0
153
282
8.24
87.06
4.8
2.2
0.23
0.22
g/l
0.45
147
265
367
1609
19.69
86.74
24.1
5.6
0.57
0.56
e9/l
0.49
359
1404
367
1612
19.63
86.46
24.2
5.6
0.04
0.04
e9/l
0.91
358
1408
239
717
6.93
82.42
10.6
4.1
—
—
—
0
0
367
1665
18.57
81.82
24.6
5.6
2.06
1.99
e9/l
0.12
362
1488
367
1671
18.46
81.31
24.9
6.0
0.16
0.19
e9/l
2.61
361
1479
99
121
10.59
78.91
3.2
1.6
—
—
—
0
0
129
259
6.92
65.98
10.6
4.6
0.62
0.74
%
0.35
78
95
122
234
7.10
65.22
10.1
4.5
0.62
0.43
%
0.54
70
76
87
120
9.02
62.39
2.9
1.4
0.24
0.23
g/l
0.25
81
114
66
8
98.90
61.12
1.6
1.5
128.37
—
e6/l
—
43
0
119
241
6.64
59.87
11.0
4.8
0.09
0.09
%
0.02
68
76
74
89
10.01
58.99
3.3
2.1
1.24
1.60
ug/l
0.18
68
84
112
231
6.38
54.96
11.2
4.8
0.31
0.03
%
0.43
59
66
152
416
5.32
54.38
3.6
2.0
—
—
—
0
0
101
198
6.51
52.02
6.1
2.9
80.60
75.73
e9/l
0.40
84
150
121
282
5.75
51.84
7.0
2.9
2.10
1.83
%
1.34
116
262
140
384
5.10
49.41
2.5
1.4
—
—
—
0
0
70
107
7.74
45.40
2.4
2.3
1.41
1.48
g/l
0.19
62
97
129
357
4.89
44.54
2.8
1.5
—
—
—
0
0
92
192
5.95
43.96
3.3
2.3
—
—
—
0
0
309
1656
5.01
42.49
14.5
6.4
9.90
10.65
umol/l
0.69
304
1569
274
1349
4.39
42.30
4.7
2.3
80.28
76.34
nmol/l
1.56
262
1214
39
0
+∞
41.38
1.2
0.0
—
—
—
0
0
185
709
4.03
40.69
3.5
2.0
3.34
2.96
mg/l
1.39
179
611
96
226
5.29
39.89
3.6
2.8
61.88
67.51
g/l
7.14
90
212
128
388
4.41
38.76
3.2
2.2
21.63
23.74
%
0.59
116
335
195
799
3.85
38.41
19.1
6.9
—
—
—
0
0
48
58
9.29
37.64
1.6
1.9
—
—
—
0
0
42
46
10.10
35.40
1.9
1.7
—
—
—
0
0
278
1491
3.94
35.37
19.7
6.5
1.21
1.22
mmol/l
0.71
250
1274
36
32
12.28
34.94
2.1
1.2
—
—
—
0
0
260
1349
3.73
34.49
18.7
5.9
1.21
1.22
mmol/l
1.70
253
1242
270
1436
3.80
34.44
28.7
8.8
0.00
0.00
e9/l
0.51
252
1169
136
478
3.82
32.84
9.4
3.5
0.80
0.82
mmol/l
0.86
130
452
41
12
37.94
32.56
2.3
1.3
—
—
—
0
0
44
60
8.13
31.17
9.4
3.6
53.91
56.25
%
0.37
44
60
101
302
4.15
30.48
4.2
1.9
286.26
369.40
nmol/l
4.27
93
271
123
427
3.73
29.92
2.7
2.4
211.84
118.81
ug/g
1.32
105
339
34
35
10.54
29.85
3.5
2.7
—
—
—
0
0
139
524
3.55
29.79
1.9
1.6
—
—
—
0
0
158
646
3.41
29.75
2.0
1.9
—
—
—
0
0
197
923
3.27
29.52
9.0
3.5
7.40
7.40
ph
0.14
45
179
130
472
3.62
29.50
1.9
1.4
690.00
560.00
titre
0.32
28
111
359
2451
6.23
29.39
16.4
3.9
14.01
10.95
mm/h
3.44
353
2264
54
98
6.23
29.37
1.5
1.4
337.07
288.43
ug/g
0.91
41
57
40
58
7.56
26.81
2.8
2.5
130.36
132.74
g/l
0.11
14
42
40
62
7.07
25.23
4.0
4.2
—
—
—
0
0
86
261
3.94
25.08
1.5
1.5
—
—
—
0
0
72
192
4.36
25.03
2.2
1.3
—
—
—
0
0
100
337
3.64
25.01
17.0
6.9
103.71
104.12
mmol/l
0.37
100
337
113
414
3.42
24.80
1.8
1.6
—
—
—
0
0
99
334
3.62
24.70
3.6
1.4
—
—
—
0
0
40
64
6.84
24.49
1.3
1.4
—
—
—
0
0
211
1125
2.89
23.65
7.5
3.2
42.34
32.46
u/l
0.70
206
1077
31
39
8.54
23.33
6.7
3.4
—
—
—
0
0
286
1806
3.13
23.16
13.4
4.7
6.77
6.51
mmol/l
0.64
276
1687
245
1427
2.90
23.00
4.5
2.7
202.66
101.11
ug/l
3.18
239
1324
161
753
2.92
22.93
4.3
2.9
1513.07
826.76
ng/l
0.92
153
619
66
181
4.18
22.00
7.7
3.6
7.40
7.41
ph
—
9
22
43
83
5.69
21.79
4.0
3.7
30.82
123.84
mg/l
0.67
32
69
43
83
5.69
21.79
4.0
3.7
27.60
27.18
mg/l
0.01
32
68
79
248
3.73
21.77
14.1
3.6
1.81
2.24
mmol/l
0.51
72
205
34
53
6.93
21.27
1.4
1.7
—
—
—
0
0
137
610
2.91
21.08
5.6
2.4
4.55
5.27
e6/l
0.36
129
552
36
61
6.39
20.81
1.3
1.4
84.85
110.08
u/ml
1.10
13
12
226
1307
2.71
20.76
18.4
10.2
1.18
1.16
inr
0.12
65
398
41
81
5.53
20.24
4.1
3.7
3.19
2.72
ratio
—
5
11
42
86
5.35
19.94
1.3
1.2
56.00
56.25
titre
—
5
8
73
233
3.62
19.51
19.1
9.0
—
—
—
0
0
147
713
2.69
18.85
3.0
1.7
1.41
1.10
mg/l
0.27
125
551
93
355
3.12
18.59
5.1
2.9
7.44
7.77
umol/l
0.06
85
304
51
132
4.29
18.24
1.6
1.2
2.56
4.47
u/ml
—
14
6
79
277
3.32
18.17
2.2
1.4
—
—
—
0
0
57
161
3.97
18.13
14.3
8.1
—
—
—
0
0
160
823
2.59
18.06
6.9
2.9
0.24
0.53
e6/l
1.31
140
600
26
36
7.66
18.01
1.8
1.1
—
—
—
0
0
178
964
2.54
18.01
5.1
2.2
—
—
—
0
0
125
580
2.69
17.28
6.0
2.8
506.82
542.97
mosm/kgh2o
1.24
119
500
41
93
4.80
17.27
2.8
2.6
—
—
—
0
0
152
788
2.51
16.60
7.8
2.6
329.53
6890.61
umol/l
3.34
145
700
169
929
2.43
16.14
4.2
2.1
111.81
232.52
u/l
1.02
162
885
294
2071
2.65
16.09
9.2
4.0
273.40
1000.39
e6/l
—
5
36
30
55
5.82
15.97
1.1
1.1
—
—
—
0
0
154
815
2.46
15.96
6.8
2.8
—
—
—
0
0
78
292
3.08
15.96
16.1
10.3
4.98
5.16
kpa
0.69
70
280
78
292
3.08
15.96
16.1
10.3
10.68
12.36
kpa
2.86
69
282
42
104
4.40
15.86
1.7
1.3
1.99
2.81
u/ml
0.35
14
15
78
294
3.06
15.76
16.3
10.3
0.58
1.38
mmol/l
0.72
59
239
187
1085
2.38
15.70
8.0
3.4
51.80
54.03
e6/l
0.04
153
746
42
105
4.36
15.67
1.6
1.2
1.70
7.08
u/ml
0.72
15
21
164
905
2.39
15.36
7.4
3.0
32.66
47.54
e6/l
0.42
143
680
72
264
3.11
15.23
17.1
10.7
95.05
95.92
%
0.76
64
257
228
1463
2.33
14.87
5.0
2.5
—
—
—
0
0
27
48
5.97
14.82
1.8
1.3
42.60
75.14
u/ml
—
6
5
25
20
13.26
14.59
1.4
1.0
—
—
—
0
0
41
107
4.16
14.45
9.0
5.1
—
—
—
0
0
107
498
2.58
14.39
2.0
1.6
1330.51
1198.97
nmol/l
0.79
94
373
138
725
2.39
14.25
4.1
2.2
—
—
—
0
0
160
898
2.32
14.17
5.2
2.7
—
—
—
0
0
302
2215
2.56
14.15
9.1
3.9
—
—
—
0
0
39
101
4.18
13.87
4.8
3.8
0.50
0.17
g/l
1.36
25
45
31
68
4.86
13.54
1.4
1.2
52.54
115.19
e6/l
0.31
26
54
31
68
4.86
13.54
1.4
1.0
2.32
6.69
e6/l
0.51
25
52
42
118
3.86
13.37
1.4
1.3
—
—
—
0
0
30
65
4.91
13.29
1.4
1.3
234.80
255.54
u/ml
0.13
20
36
34
83
4.39
13.04
1.7
1.2
18.83
34.27
u/ml
—
12
9
39
106
3.97
12.99
15.3
10.9
—
—
—
0
0
25
26
10.19
12.92
1.2
1.2
—
—
—
0
0
20
13
16.13
12.75
4.9
1.5
21.50
32.31
umol/l
2.10
20
13
19
12
16.56
12.26
2.8
1.8
82.62
69.86
ug/l
0.27
19
12
117
608
2.31
12.10
1.8
1.7
487.30
439.06
pmol/l
1.22
110
509
49
164
3.27
11.97
20.1
10.5
24.77
24.92
mmol/l
0.08
44
157
126
679
2.26
11.93
2.3
1.4
21.04
21.72
nmol/l
0.22
121
577
24
27
9.39
11.92
1.7
1.0
0.44
0.48
u/ml
0.04
16
14
187
1180
2.11
11.83
2.5
1.8
93.16
97.02
pmol/l
0.61
130
589
92
434
2.46
11.80
1.3
1.2
—
—
—
0
0
43
135
3.45
11.61
9.2
3.6
—
—
—
0
0
21
20
11.02
11.40
1.2
1.2
—
—
—
0
0
43
139
3.35
11.09
19.4
2.6
0.63
0.65
%
0.16
43
139
15
7
22.20
10.76
1.7
1.6
—
—
—
0
0
145
857
2.09
10.66
7.4
3.4
0.00
0.00
estimate
-0.00
61
294
25
56
4.70
10.64
1.4
1.2
—
—
—
0
0
199
1321
2.02
10.62
5.3
3.0
5.65
5.89
ph
—
10
109
229
1600
2.03
10.55
6.2
3.3
0.00
0.00
estimate
0.50
61
314
60
243
2.73
10.45
7.1
3.1
—
—
—
0
0
21
24
9.18
10.41
1.2
1.3
—
—
—
0
0
81
381
2.42
10.36
1.5
1.3
—
—
—
0
0
229
1611
2.01
10.23
7.6
4.5
0.00
0.00
estimate
-0.00
61
300
229
1626
1.98
9.79
6.2
3.3
0.00
0.01
estimate
0.50
59
285
21
27
8.15
9.75
2.4
2.9
—
—
—
0
0
17
15
11.78
9.65
1.5
1.8
—
—
—
0
0
173
1121
1.97
9.62
6.0
3.3
23.91
32.25
ng/l
0.67
132
710
49
187
2.85
9.52
4.1
2.3
155.24
132.98
ng/l
0.14
38
167
25
62
4.24
9.39
1.2
1.1
—
—
—
0
0
15
11
14.12
9.25
8.3
5.5
32.83
50.59
%
0.98
15
11
166
1075
1.94
9.13
6.9
3.3
2.32
2.36
mmol/l
3.14
154
945
54
223
2.65
9.02
3.3
2.4
5.19
5.23
e9/l
0.01
42
189
22
51
4.51
8.98
6.2
3.0
—
—
—
0
0
21
31
7.09
8.96
5.2
2.1
—
—
—
0
0
30
89
3.57
8.81
1.2
1.2
—
—
—
0
0
122
724
1.99
8.56
6.2
3.1
—
—
—
0
0
20
30
6.96
8.47
4.9
2.1
32.90
32.50
pg
0.13
20
30
98
544
2.07
8.23
5.3
3.4
85.34
212.84
ng/l
1.09
74
385
375
3319
3.69
8.08
58.1
12.1
17.70
21.27
mg/l
2.38
364
2528
63
297
2.33
7.92
2.5
2.3
33.25
28.94
u/l
0.40
57
251
38
141
2.88
7.76
22.5
14.7
—
—
—
0
0
15
17
9.12
7.61
1.3
1.1
—
—
—
0
0
14
15
9.63
7.34
1.1
1.1
—
—
—
0
0
18
42
4.44
7.29
5.7
3.0
—
—
—
0
0
15
19
8.16
7.17
1.9
1.4
—
—
—
0
0
17
27
6.53
7.01
1.4
1.1
—
—
—
0
0
11
8
14.10
6.93
1.5
1.5
—
—
—
0
0
18
32
5.84
6.84
1.1
1.3
—
—
—
0
0
10
7
14.61
6.43
1.3
1.4
—
—
—
0
0
17
42
4.19
6.42
1.1
1.3
—
—
nmol/l
—
0
0
18
36
5.19
6.26
2.2
2.6
—
—
—
0
0
11
11
10.25
6.07
1.0
1.1
1297.18
1749.64
miu/ml
0.38
11
11
9
6
15.30
5.93
1.2
1.2
—
—
—
0
0
13
21
6.36
5.43
4.8
3.0
2.63
2.54
g/24h
—
7
14
16
43
3.84
5.42
2.1
1.5
—
—
—
0
0
10
11
9.29
5.31
1.0
1.2
—
—
—
0
0
13
22
6.07
5.26
1.5
1.4
42892.86
14348.00
e6/l
—
7
10
17
49
3.58
5.23
1.2
1.3
0.48
0.50
nmol/l
0.16
17
44
32
135
2.49
5.13
1.3
1.2
—
—
—
0
0
16
45
3.66
5.10
3.2
1.9
1.65
1.56
mmol/l
0.23
16
45
18
56
3.32
4.95
1.2
1.2
2.33
3.78
u/ml
—
6
23
18
56
3.32
4.95
2.1
1.4
—
—
—
0
0
16
46
3.58
4.94
1.1
1.3
—
—
—
0
0
17
51
3.44
4.94
1.2
1.0
—
15.94
—
0
5
77
469
1.80
4.72
6.4
2.7
2.59
3.20
e6/l
0.35
50
235
10
14
7.30
4.68
1.5
2.1
—
—
—
0
0
17
53
3.31
4.67
5.9
2.8
16.34
16.17
%
0.05
12
24
12
22
5.59
4.63
2.5
2.0
—
—
—
0
0
7
5
14.22
4.59
2.4
3.8
—
—
—
0
0
7
5
14.22
4.59
1.3
1.2
—
—
—
0
0
133
949
1.61
4.51
4.4
3.1
6.97
7.68
mmol/l
1.10
125
818
116
801
1.64
4.49
1.4
1.3
0.72
1.71
u/ml
0.91
24
223
18
60
3.10
4.45
1.1
1.1
—
—
—
0
0
52
285
1.95
4.42
1.2
1.2
—
—
—
0
0
8
9
9.04
4.30
1.1
1.0
—
—
—
0
0
8
9
9.04
4.30
1.3
1.7
—
—
—
0
0
13
29
4.60
4.28
1.2
1.1
—
—
—
0
0
9
13
7.06
4.18
3.6
3.0
36986.70
37031.15
ug/l
—
9
13
20
74
2.79
4.15
1.6
1.2
—
—
—
0
0
22
86
2.65
4.12
29.8
11.6
1.32
1.21
mmol/l
0.29
16
75
29
130
2.33
4.10
2.4
1.5
—
—
—
0
0
49
270
1.93
4.10
6.8
3.4
—
—
—
0
0
13
32
4.16
3.94
1.6
1.2
—
—
—
0
0
28
127
2.30
3.87
2.6
3.3
32.91
1275.91
u/ml
0.58
23
106
17
60
2.92
3.84
1.1
1.1
—
—
—
0
0
104
724
1.59
3.83
7.3
3.4
1.02
1.02
kg/l
—
8
100
18
66
2.81
3.81
1.4
1.2
—
—
—
0
0
54
317
1.82
3.73
3.2
4.2
3.64
6.77
ug/l
1.07
41
262
92
1287
0.63
3.71
2.8
2.7
—
—
—
0
0
12
30
4.09
3.62
1.0
1.1
—
—
—
0
0
91
624
1.60
3.55
1.4
1.3
16.19
33.96
iu/ml
2.71
26
208
6
6
10.13
3.51
3.3
1.5
—
—
—
0
0
89
611
1.59
3.45
1.3
1.3
13.97
9.78
u/ml
0.19
36
250
13
37
3.60
3.43
1.1
1.2
—
—
—
0
0
9
18
5.09
3.39
4.1
1.9
—
—
—
0
0
169
1337
1.46
3.34
2.7
2.1
—
—
—
0
0
10
23
4.43
3.33
2.5
1.7
—
—
—
0
0
35
186
1.97
3.27
1.0
1.1
—
106.00
—
0
5
31
158
2.04
3.24
2.4
2.2
—
—
—
0
0
115
847
1.51
3.23
4.9
3.2
2087.02
387.96
mg/l
1.09
73
532
41
231
1.86
3.23
1.7
1.4
—
—
—
0
0
12
34
3.61
3.22
2.1
1.4
—
—
—
0
0
47
277
1.79
3.21
12.0
4.3
—
—
—
0
0
7
11
6.45
3.20
1.0
1.0
—
—
—
0
0
7
11
6.45
3.20
1.0
1.0
—
—
—
0
0
7
11
6.45
3.20
1.0
1.0
—
—
—
0
0
7
11
6.45
3.20
2.3
3.1
—
—
—
0
0
304
3310
0.64
3.19
4.4
4.3
4.67
4.79
mmol/l
1.12
292
3092
65
422
1.65
3.15
1.4
1.2
—
—
—
0
0
14
50
2.87
3.12
1.1
1.3
—
—
—
0
0
25
119
2.18
3.11
1.7
1.2
—
—
—
0
0
303
3296
0.65
3.07
4.3
4.2
1.44
1.49
mmol/l
1.33
291
3067
10
26
3.92
3.00
2.9
2.7
—
—
—
0
0
5
5
10.10
2.98
2.8
1.4
48.20
36.60
umol/l
—
5
5
5
5
10.10
2.98
1.0
1.0
—
—
—
0
0
5
5
10.10
2.98
1.0
1.0
—
—
—
0
0
5
5
10.10
2.98
1.0
1.0
—
—
—
0
0
293
2606
1.49
2.94
5.0
3.9
15.17
14.57
pmol/l
3.22
280
2385
25
122
2.12
2.94
1.7
2.2
5228.00
4080.96
u/l
—
8
45
14
52
2.75
2.92
1.5
1.4
0.29
0.30
nmol/l
—
9
40
7
13
5.46
2.88
1.1
1.2
—
—
—
0
0
14
53
2.70
2.82
1.4
1.1
—
—
—
0
0
15
59
2.60
2.82
46.8
3.0
—
—
—
0
0
52
328
1.67
2.81
1.8
1.7
—
—
—
0
0
8
18
4.51
2.81
3.0
2.9
—
—
—
0
0
5
6
8.42
2.75
1.0
1.0
—
—
—
0
0
7
14
5.07
2.74
2.0
1.1
—
—
—
0
0
8
19
4.27
2.69
1.8
1.3
—
—
—
0
0
23
114
2.08
2.62
1.1
1.4
422.90
244.38
miu/ml
—
8
59
7
15
4.73
2.61
1.1
1.1
98.57
187.71
mmol/24h
—
7
15
9
25
3.66
2.59
1.1
1.2
—
—
—
0
0
116
890
1.43
2.58
5.1
3.8
33.49
10.62
mg/mmol
1.15
78
549
9
26
3.52
2.49
1.3
1.7
0.67
3.67
u/field
—
9
12
313
3354
0.68
2.44
4.8
4.7
2.69
2.86
mmol/l
2.46
299
3116
11
38
2.95
2.43
2.6
1.6
90.91
90.29
%
0.20
11
38
37
222
1.74
2.41
1.2
1.3
—
—
—
0
0
6
12
5.06
2.41
1.0
1.2
—
—
—
0
0
13
52
2.55
2.38
1.7
1.1
105.17
10.45
iu/ml
—
6
11
294
3183
0.70
2.38
4.2
3.8
1.44
1.29
mmol/l
2.54
284
2949
117
914
1.40
2.33
5.3
3.0
—
—
—
0
0
9
28
3.26
2.32
1.3
1.1
—
—
—
0
0
77
558
1.47
2.30
3.8
2.7
2.46
2.44
mmol/l
0.67
69
489
11
42
2.66
2.16
1.5
1.6
—
—
—
0
0
10
37
2.75
2.08
2.8
7.4
7.91
6.24
mmol/l
—
10
30
23
397
0.55
2.06
1.2
1.4
—
—
—
0
0
368
3509
1.74
2.02
41.5
11.2
—
—
—
0
0
40
259
1.61
1.99
2.4
2.4
—
16.76
—
0
15
37
235
1.63
1.99
1.2
1.3
—
33.10
—
0
13
5
11
4.59
1.94
3.2
1.3
—
—
—
0
0
8
28
2.89
1.87
1.0
1.3
—
—
—
0
0
5
12
4.21
1.83
4.4
1.9
—
—
—
0
0
9
35
2.61
1.81
1.7
1.3
—
—
—
0
0
12
235
0.50
1.63
1.6
1.4
—
—
—
0
0
25
386
0.62
1.49
1.8
1.6
—
—
—
0
0
9
38
2.40
1.46
1.9
3.0
2.36
3.22
nmol/l
—
9
38
5
16
3.15
1.44
1.6
1.4
105.60
148.62
nmol/l
—
5
16
51
375
1.41
1.44
1.4
1.5
—
—
—
0
0
21
127
1.69
1.39
1.5
2.3
—
—
—
0
0
15
82
1.86
1.37
1.7
2.9
—
—
—
0
0
5
17
2.96
1.36
2.8
2.6
23.00
29.55
umol/l
—
5
11
8
34
2.38
1.30
1.5
1.1
—
—
—
0
0
245
2244
1.24
1.29
5.0
3.5
—
—
—
0
0
31
213
1.49
1.25
2.1
2.8
59.16
44.80
u/ml
0.29
31
207
9
45
2.02
1.24
3.2
1.8
—
—
—
0
0
8
37
2.19
1.22
1.0
1.0
—
—
—
0
0
6
26
2.33
1.19
1.3
1.2
—
—
—
0
0
5
20
2.52
1.15
1.6
1.3
—
—
—
0
0
12
206
0.57
1.11
2.0
1.7
—
—
—
0
0
5
21
2.40
1.09
1.6
1.4
1.72
1.54
g/l
—
5
21
323
3086
1.26
0.98
6.1
4.7
1.94
2.25
mu/l
0.36
311
2848
7
36
1.96
0.97
3.0
2.6
103.14
105.97
mmol/l
—
7
36
7
36
1.96
0.97
3.0
2.6
4.13
3.91
mmol/l
—
7
36
17
112
1.54
0.86
2.5
3.2
—
—
—
0
0
100
872
1.20
0.80
5.1
3.6
—
—
—
0
0
0
26
0.00
0.78
0.0
1.3
—
—
—
0
0
9
53
1.71
0.76
1.0
1.1
—
—
—
0
0
9
55
1.65
0.74
3.6
3.2
6.60
7.20
mmol/l
—
9
55
22
161
1.39
0.70
1.5
2.1
—
—
—
0
0
22
161
1.39
0.70
1.5
2.1
—
—
—
0
0
22
161
1.39
0.70
1.5
2.1
—
—
—
0
0
6
105
0.56
0.62
1.5
1.3
—
—
—
0
0
5
30
1.67
0.61
9.0
17.3
1496.80
1544.37
nmol/l
—
5
30
8
53
1.52
0.58
7.9
5.7
337.25
355.61
umol/l
—
8
46
19
141
1.37
0.57
3.4
3.1
—
—
—
0
0
20
150
1.35
0.57
1.5
2.2
—
—
—
0
0
6
36
1.68
0.57
3.3
2.6
—
—
—
0
0
21
160
1.33
0.54
1.5
1.9
—
—
—
0
0
9
65
1.39
0.51
2.9
2.4
—
—
—
0
0
13
94
1.40
0.46
1.9
2.6
—
—
—
0
0
10
70
1.44
0.42
3.2
2.1
—
—
—
0
0
8
59
1.36
0.41
1.4
1.5
35.40
24.54
u/l
—
8
50
315
3223
0.89
0.40
5.1
4.3
5.88
5.85
mmol/l
0.12
304
2972
10
73
1.38
0.35
3.0
4.2
—
—
—
0
0
20
164
1.23
0.33
1.1
1.1
—
—
—
0
0
6
46
1.31
0.33
2.5
2.2
13.90
13.19
%
—
6
46
31
268
1.17
0.31
1.3
1.2
74.11
152.13
iu/ml
1.18
14
110
296
3022
0.92
0.28
6.2
5.3
39.83
39.19
mmol/mol
0.44
284
2828
93
874
1.08
0.25
1.6
1.5
—
—
—
0
0
9
74
1.22
0.25
1.2
1.7
223.56
232.44
pmol/l
—
9
68
5
38
1.32
0.23
2.2
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
1.81
—
0
10
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
296
2909
1.07
0.21
54.1
15.7
330.45
332.75
g/l
4.03
296
2893
375
3734
1.09
0.09
71.6
18.2
39.15
40.63
%
6.19
357
3521
16
175
0.91
0.08
1.1
1.1
—
—
—
0
0
375
3736
1.08
0.07
70.1
18.0
29.99
30.26
pg
1.72
375
3683
375
3736
1.08
0.07
70.2
18.0
90.64
90.74
fl
0.14
375
3683
375
3740
1.06
0.04
70.9
18.2
129.51
136.42
g/l
14.04
375
3685
21
201
1.05
0.03
4.0
2.2
—
—
—
0
0
44
432
1.02
0.01
2.8
2.8
0.74
0.70
ug/l
0.08
34
264
90
907
0.99
0.01
1.5
1.6
1.36
1.41
mmol/l
0.30
81
775
12
122
0.98
0.00
1.8
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.5
—
169.63
—
0
8
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
8
80
1.00
-0.00
1.4
1.3
—
—
—
0
0
6
64
0.94
-0.00
1.5
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
64
0.94
-0.00
1.5
1.5
—
—
—
0
0
6
66
0.91
-0.00
1.5
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
16.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
10.44
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint D3_NONHEREDHYPOGAMMA and mortality.

Females

Parameter HR [95% CI] p-value
D3_NONHEREDHYPOGAMMA 3.869 [3.03, 4.95] < 0.001
Birth year 0.991 [0.98, 1.0] 0.063

During the follow-up period (1.1.1998 — 31.12.2019), 147 out of 714 females with D3_NONHEREDHYPOGAMMA died.

Males

Parameter HR [95% CI] p-value
D3_NONHEREDHYPOGAMMA 3.065 [2.24, 4.19] < 0.001
Birth year 0.987 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 99 out of 457 males with D3_NONHEREDHYPOGAMMA died.

Mortality risk

Mortality risk for people of age

years, who have D3_NONHEREDHYPOGAMMA.

N-year risk Females Males
1 0.361% 0.457%
5 2.14% 3.087%
10 5.093% 8.232%
15 9.046% 16.041%
20 15.845% 25.789%

Relationships between endpoints

↥

Index endpoint: D3_NONHEREDHYPOGAMMA – Nonhereditary hypogammaglobulinemia

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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