Other and unspecified immunodeficiencies with predominantly antibody defects

D3_IMMUDEFANTIBODYNAS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D80.8, D80.9
  • Hospital discharge: ICD-9 2790C|2790X
  • Cause of death: ICD-10 D80.8, D80.9
  • Cause of death: ICD-9 2790C|2790X

2 out of 7 registries used, show all original rules.

456

4. Check minimum number of events

None

456

5. Include endpoints

None

456

6. Filter based on genotype QC (FinnGen only)

438

Control definitions (FinnGen only)

Control exclude
D3_IMMUNEMECHANISM

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1635 939 695
Only index persons 1497 874 623
Unadjusted period prevalence (%)
Whole population 0.02 0.03 0.02
Only index persons 0.03 0.03 0.02
Median age at first event (years)
Whole population 44.50 48.34 39.35
Only index persons 44.51 48.28 39.22

-FinnGen-

Key figures

All Female Male
Number of individuals 438 291 147
Unadjusted period prevalence (%) 0.09 0.10 0.07
Median age at first event (years) 50.78 51.10 50.16

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
456
Matched controls
4560
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
+∞
307.7
275
*
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
+∞
253.6
219
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
27.0
212.3
163
92
ZX120
NOMESCO Finland
Intravenous
17.6
205.3
218
226
WW200
NOMESCO Finland
Immunization
43.6
203.3
127
40
120
Kela drug reimbursment
Hypogammaglobulinaemia
+∞
183.0
163
*
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
+∞
178.1
159
*
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
+∞
176.9
158
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
18.4
148.1
133
100
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
25.6
130.2
96
47
J01MA14
ATC
moxifloxacin; systemic
11.9
126.0
155
189
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
18.3
114.4
99
68
J01MA12
ATC
levofloxacin; systemic
8.2
109.9
213
440
J47
ICD-10 Finland
Bronchiectasis
32.0
109.2
73
27
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
10.5
108.4
144
192
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
+∞
104.3
96
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
8.7
97.8
357
1334
6BA02, ,
NOMESCO Finland
291.1
94.5
93
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
6.9
93.8
228
578
TPH04
NOMESCO Finland
Cathetrisation of vein
6.9
93.6
228
579
TDM10
NOMESCO Finland
Puncture of maxillary antrum
13.7
93.1
95
86
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.6
91.5
171
333
H02AB07
ATC
prednisone; oral
7.3
86.6
166
330
J45.1
ICD-10 Finland
Nonallergic asthma
9.2
86.3
123
176
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
9.6
86.0
117
158
H02AB06
ATC
prednisolone; systemic
8.0
85.0
363
1501
R03BB04
ATC
tiotropium bromide; inhalant
8.8
79.4
116
170
R50.9
ICD-10 Finland
Fever, unspecified
6.5
79.2
177
406
C01CA24
ATC
epinephrine; parenteral
8.3
76.4
118
184
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
12.4
75.8
81
78
UGC12
NOMESCO Finland
Flexible bronchoscopy
9.6
73.5
97
125
D80.0
ICD-10 Finland
Hereditary hypogammaglobulinaemia
+∞
72.9
68
*
XW000
NOMESCO Finland
Bone marrow biopsy
13.0
72.9
75
68
H02AB09
ATC
hydrocortisone; systemic
15.2
72.3
67
51
J45.0
ICD-10 Finland
Predominantly allergic asthma
7.1
70.6
130
244
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
8.9
70.3
99
138
TGC00
NOMESCO Finland
Bronchial lavation
15.8
68.6
62
45
J46
ICD-10 Finland
Status asthmaticus
16.2
68.6
61
43
R03DC03
ATC
montelukast; oral
5.5
66.8
184
500
Z3231
NOMESCO Finland
Registered nurse
5.1
65.8
247
863
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.0
64.8
237
809
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.8
63.2
117
219
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
8.9
62.9
87
118
R03DA04
ATC
theophylline; systemic, rectal
10.9
62.4
72
77
J32.4
ICD-10 Finland
Chronic pansinusitis
24.9
62.3
45
20
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
5.0
58.7
182
538
J45.9
ICD-10 Finland
Asthma, unspecified
4.9
58.1
182
542
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
4.9
57.1
178
527
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.5
56.7
243
916
Z2221
NOMESCO Finland
Medical doctor
4.5
56.2
234
863
Z3226
NOMESCO Finland
Physiotherapist
4.7
54.0
181
564
R03BA02
ATC
budesonide; inhalant
4.7
53.8
174
527
H02AB04
ATC
methylprednisolone; systemic
5.2
53.2
138
349
R03AC12
ATC
salmeterol; inhalant
9.5
53.2
68
83
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
7.8
51.9
79
119
R03BB01
ATC
ipratropium bromide; inhalant
11.1
49.9
56
57
J01.0
ICD-10 Finland
Acute maxillary sinusitis
4.2
49.8
216
806
XF400
NOMESCO Finland
ECG with 12 standard connections
4.9
49.3
137
365
WW500
NOMESCO Finland
Blood transfusion
9.7
48.4
60
70
R4110
NOMESCO Finland
Physiotherapy
4.1
48.4
222
858
J01FA06
ATC
roxithromycin; oral
4.1
48.1
285
1312
R03AC13
ATC
formoterol; inhalant
8.0
48.0
71
103
J45.8
ICD-10 Finland
Mixed asthma
11.2
47.8
53
53
R03AK06
ATC
salmeterol and fluticasone; inhalant
4.8
47.2
137
377
UDH02
NOMESCO Finland
Rhinopharyngoscopy
6.3
46.2
88
167
ZXE10
NOMESCO Finland
More than one and less than three hours
3.9
45.5
257
1134
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
19.5
45.1
36
20
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
6.1
43.7
85
164
GD1AD
NOMESCO Finland
Thorax CT examination
7.7
43.6
66
98
JN4BD
NOMESCO Finland
Extensive body CT
5.3
42.6
99
225
R03AK11
ATC
formoterol and fluticasone; inhalant
12.1
42.2
44
40
A07AA02
ATC
nystatin; oral
7.0
40.8
68
112
Z2446
NOMESCO Finland
Social worker
5.4
40.6
92
204
Z01.8
ICD-10 Finland
Other specified special examinations
3.8
40.5
175
636
L03AA02
ATC
filgrastim; parenteral
9.7
40.0
49
56
UJF30
NOMESCO Finland
Ileoscopy through colon
5.1
40.0
97
228
R01AD05
ATC
budesonide; nasal
5.6
39.9
85
178
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
6.6
39.3
69
120
WX408
NOMESCO Finland
General anesthesy, balanced
3.6
39.1
200
809
ZXE00
NOMESCO Finland
One hour or less
3.6
39.1
268
1303
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
7.9
38.6
56
79
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.5
38.4
68
119
M05BA04
ATC
alendronic acid; oral
6.1
38.4
74
141
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.2
37.0
121
359
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
10.9
35.9
40
40
J05AB11
ATC
valaciclovir; oral
3.9
35.8
135
442
R03AK08
ATC
formoterol and beclometasone; inhalant
7.3
35.7
56
86
L04AX01
ATC
azathioprine; systemic
7.8
35.5
52
74
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
10.6
35.2
40
41
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.7
34.6
92
232
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
49.9
34.4
41
9
R01AD08
ATC
fluticasone; nasal
3.3
34.3
211
941
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.8
34.2
68
133
R03AC02
ATC
salbutamol; inhalant
3.7
33.9
342
2041
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.0
33.9
82
191
WE300
NOMESCO Finland
Profylactive therapy of malignancy with biomoidiers
+∞
33.8
32
*
D83.9
ICD-10 Finland
Common variable immunodeficiency, unspecified
+∞
33.8
32
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.9
33.7
124
398
J01MA02
ATC
ciprofloxacin; systemic
3.2
33.5
230
1091
ZXD10
NOMESCO Finland
Scheduled procedure
3.2
33.4
245
1208
R03DC01
ATC
zafirlukast; oral
11.8
33.3
35
32
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
3.5
33.1
332
1962
R01AD09
ATC
mometasone; nasal
3.3
33.1
296
1634
ZX112
NOMESCO Finland
Subcutaneous
9.6
32.9
40
45
J01FA15
ATC
telithromycin; oral
4.4
32.9
95
255
A03FA01
ATC
metoclopramide; systemic, rectal
3.4
32.6
165
650
J01FF01
ATC
clindamycin; systemic
3.3
32.5
184
776
R03AK07
ATC
formoterol and budesonide; inhalant
3.4
31.7
157
609
J02AC01
ATC
fluconazole; systemic
3.1
31.6
263
1381
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
6.2
31.5
58
105
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
6.3
31.2
56
99
XQ800
NOMESCO Finland
Prick test
4.7
30.7
81
202
ZXA10
NOMESCO Finland
Bilateral
3.5
30.7
140
515
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
5.3
30.5
68
147
JN4AD
NOMESCO Finland
Body CT examination
4.7
30.2
78
191
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.4
30.2
145
550
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.6
30.1
81
205
ZX108
NOMESCO Finland
Inhalation
48.7
30.1
36
8
D70.82
ICD-10 Finland
Drug-induced neutropenia
10.2
30.1
35
37
J01FA10
ATC
azithromycin; systemic
3.6
30.0
357
2275
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
53.9
29.8
35
7
J45
ICD-10 Finland
Asthma
4.3
29.5
88
241
ZX114
NOMESCO Finland
Intramuscular
10.1
29.2
34
36
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
3.2
29.1
318
1912
TAB00
NOMESCO Finland
Lumbar puncture
5.6
28.6
58
115
J01FA09
ATC
clarithromycin; systemic
3.0
28.5
214
1045
A41.9
ICD-10 Finland
Sepsis, unspecified
7.8
28.4
41
57
R03BA05
ATC
fluticasone; inhalant
3.2
28.0
147
585
TPX10
NOMESCO Finland
Implantation of vascular injection port
8.5
27.6
37
47
D80.2
ICD-10 Finland
Selective deficiency of immunoglobulin A [IgA]
+∞
27.4
26
*
R05
ICD-10 Finland
Cough
3.2
27.1
149
608
C03CA01
ATC
furosemide; systemic
3.2
26.9
145
584
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.9
26.8
188
878
J31.0
ICD-10 Finland
Chronic rhinitis
4.1
26.6
84
239
D84.18
ICD-10 Finland
Other specified defect in the complement system
+∞
26.3
25
*
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
6.4
25.8
45
77
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
5.6
25.4
51
100
L04AA06
ATC
mycophenolic acid; systemic
10.3
25.2
29
30
D83.0
ICD-10 Finland
Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
+∞
25.2
24
*
XA800
NOMESCO Finland
Neuropsychological investigation
5.0
25.1
58
129
N02AX02
ATC
tramadol; systemic, rectal
2.7
24.5
240
1318
A01AB09
ATC
miconazole; local oral
4.3
24.5
71
189
R03AK03
ATC
[U] fenoterol and ipratropium bromide
6.6
24.5
41
67
A04AA01
ATC
ondansetron; systemic, rectal
4.3
23.9
67
174
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.6
23.6
60
144
N02AA05
ATC
oxycodone; systemic
3.3
23.5
106
381
R03BA01
ATC
beclometasone; inhalant
3.4
23.4
101
353
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
4.3
23.2
66
173
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
6.6
23.2
39
64
UJF32
NOMESCO Finland
Coloscopy
2.9
23.1
150
663
J01DA06
ATC
[U] cefuroxime
3.2
23.1
113
426
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.4
23.1
100
350
R06AE07
ATC
cetirizine; oral
2.7
22.9
262
1539
R03BA08
ATC
ciclesonide; inhalant
3.8
22.8
77
229
N03AX16
ATC
[U] pregabalin
2.9
22.8
150
668
R01AD58
ATC
fluticasone, combinations; nasal
2.8
22.7
166
780
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.6
22.7
221
1198
A02BC02
ATC
pantoprazole; systemic
3.0
22.7
344
2320
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
5.1
22.5
50
107
R06.0
ICD-10 Finland
Dyspnoea
2.8
22.4
157
721
ZXE20
NOMESCO Finland
More than three and less than five hours
3.3
22.4
98
345
Z3229
NOMESCO Finland
Other healthcare associate professional
4.0
22.2
70
198
J05AB01
ATC
aciclovir; systemic
2.8
22.2
150
676
WZC30
NOMESCO Finland
Teaching
3.1
21.6
108
411
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
8.7
21.6
28
34
XG410
NOMESCO Finland
Flow-volume spirometry
6.4
21.6
37
62
S01GX01
ATC
cromoglicic acid; ophthalmic
2.8
21.5
148
672
1XC02, ,
NOMESCO Finland
35.7
21.4
27
8
D64.9
ICD-10 Finland
Anaemia, unspecified
4.0
21.3
66
184
J01AA02
ATC
doxycycline; systemic
3.5
21.2
390
2865
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
8.9
21.2
27
32
R01BA52
ATC
pseudoephedrine, combinations; oral
2.6
21.2
188
967
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
20.7
21.1
31
16
J20
ICD-10 Finland
Acute bronchitis
3.5
21.1
84
278
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
7.2
21.1
32
47
D84.9
ICD-10 Finland
Immunodeficiency, unspecified
+∞
21.0
20
*
2790C
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[DEFICIENTIA IMMUNOGLOBULINI ALIA]
+∞
21.0
20
*
WZC00
NOMESCO Finland
Treatment plan or consultation
2.6
21.0
211
1151
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
6.7
20.8
34
54
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
19.5
20.7
31
17
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
34.3
20.4
26
8
ZY010
NOMESCO Finland
Hospital outpatient
4.3
20.3
56
143
H04.10
ICD-10 Finland
Dry eye syndrome
3.3
20.3
89
313
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.5
20.2
228
1305
R4120
NOMESCO Finland
Occupational therapy
4.0
20.1
62
172
D80.6
ICD-10 Finland
Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
+∞
19.9
19
*
R1250
NOMESCO Finland
Evaluation of functional capability
6.8
19.9
32
50
M04AA01
ATC
allopurinol; systemic
3.8
19.9
68
203
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
8.1
19.7
27
35
ZXA05
NOMESCO Finland
Left side
2.7
19.7
142
656
R03AC03
ATC
terbutaline; inhalant
3.1
19.5
97
367
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
19.3
19.4
29
16
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
3.3
19.2
81
277
A28
ICPC
Limited function/disability NOS
3.2
19.0
87
313
Z2445
NOMESCO Finland
Psychologist
4.4
18.9
51
128
A02BC01
ATC
omeprazole; systemic
2.6
18.7
154
757
RD210, ,
NOMESCO Finland
6.2
18.6
33
57
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.5
18.6
70
223
XF600
NOMESCO Finland
Bloodpressure measurement
4.1
18.5
54
144
Z50.1
ICD-10 Finland
Other physical therapy
4.8
18.4
44
100
ZXD05
NOMESCO Finland
Urgent procedure
2.5
18.4
177
934
J01DB01
ATC
cefalexin; oral
4.0
18.3
414
3249
ZYC01
NOMESCO Finland
Remote contact by phone
4.1
18.1
54
146
RS221, ,
NOMESCO Finland
7.6
18.0
26
36
WX002
NOMESCO Finland
Sedation and analgesia
2.8
17.9
115
498
N05CD07
ATC
temazepam; oral
3.5
17.8
68
218
A01AB04
ATC
amphotericin B; local oral
4.8
17.7
42
95
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.3
17.7
37
75
ZXD20
NOMESCO Finland
Day surgery
3.0
17.6
90
344
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
17.8
17.6
27
16
N03AX12
ATC
[U] gabapentin; oral
2.7
17.6
112
483
N06AX21
ATC
duloxetine; oral
3.0
17.5
90
345
N05CF01
ATC
zopiclone; oral
2.4
17.5
174
927
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.4
17.4
69
227
J01DA01
ATC
[U] cefalexin
2.4
17.2
315
2178
ZXA00
NOMESCO Finland
Right side
2.5
17.1
147
733
M36.8*D80.1
ICD-10 Finland
Systemic disorders of connective tissue in hypogammaglobulinaemia
+∞
16.8
16
*
N03AE01
ATC
clonazepam; systemic
4.1
16.7
48
126
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.3
16.5
69
234
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
4.8
16.5
39
88
JN3AD
NOMESCO Finland
Abdominal CT examination
3.2
16.4
71
246
WX892
NOMESCO Finland
Monitored bed care
3.7
16.2
54
158
R06AE09
ATC
levocetirizine; oral
2.8
16.1
98
411
J01DA08
ATC
[U] cefaclor
3.0
16.0
80
301
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.2
16.0
69
238
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.1
16.0
77
284
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.8
16.0
96
400
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
5.8
15.9
30
55
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.2
15.9
72
256
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.5
15.9
136
673
R81
ICPC
Pneumonia
5.6
15.8
31
59
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
15.5
15.5
25
17
UJF92
NOMESCO Finland
Capsular endoscopy
6.7
15.5
25
39
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
5.3
15.5
32
64
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.2
15.5
69
243
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
15.4
85
338
R06AX27
ATC
desloratadine; oral
2.3
15.4
179
1010
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
4.3
15.3
41
102
E0000UV, ,
ATC
2.2
15.2
227
1414
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.8
15.2
35
77
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.3
15.2
174
974
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
46.7
15.2
18
*
N05BA01
ATC
diazepam; systemic, rectal
2.8
15.2
87
353
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
5.1
15.0
32
66
R4190
NOMESCO Finland
Nutritional therapy
4.2
14.9
41
104
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.0
14.9
75
283
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
5.9
14.8
27
48
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.5
14.8
55
173
D86.0
ICD-10 Finland
Sarcoidosis of lung
+∞
14.7
14
*
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
6.1
14.6
26
45
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.5
14.6
54
169
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.7
14.5
35
80
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.6
14.4
97
426
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
6.4
14.3
24
39
A02BC05
ATC
esomeprazole; systemic
2.2
14.3
214
1325
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
5.4
14.3
29
57
Z71.8
ICD-10 Finland
Other specified counselling
2.2
14.3
176
1010
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.3
14.2
57
188
C10AC01
ATC
colestyramine; oral
5.7
14.2
27
50
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
5.5
14.1
28
54
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
16.4
14.1
22
14
L01BA01
ATC
methotrexate; systemic
5.1
14.0
30
62
R11
ICD-10 Finland
Nausea and vomiting
3.1
13.8
62
219
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.9
13.8
72
277
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.6
13.7
47
140
L04AX03
ATC
methotrexate; systemic
3.0
13.7
66
243
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
10.5
13.6
26
26
XCK00
NOMESCO Finland
Perimetry
4.0
13.6
40
107
R01AD12
ATC
fluticasone furoate; nasal
2.1
13.6
183
1084
J01
ICD-10 Finland
Acute sinusitis
3.6
13.5
46
136
AA1AD
NOMESCO Finland
CT of head and brain
2.3
13.5
133
693
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
6.3
13.5
23
38
R06AX22
ATC
ebastine; oral
2.4
13.5
110
528
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.0
13.5
39
103
X59
ICD-10 Finland
Exposure to unspecified factor
2.4
13.4
115
564
R13
ICD-10 Finland
Dysphagia
3.5
13.4
48
147
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
4.5
13.3
33
77
R01AD11
ATC
triamcinolone; nasal
3.0
13.3
63
229
A02BA02
ATC
ranitidine; systemic
2.5
13.3
101
469
XF404
NOMESCO Finland
Ambulatory ECG
3.3
13.3
53
174
WX402
NOMESCO Finland
General anaesthesia
2.3
13.2
124
633
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
4.5
13.1
33
78
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.1
13.0
28
58
ZX121
NOMESCO Finland
Central venous catheter
19.8
13.0
19
10
R03BC03
ATC
nedocromil; inhalant
3.3
13.0
52
171
J01FA01
ATC
erythromycin; systemic
2.6
13.0
84
361
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.4
12.9
102
482
R51.81
ICD-10 Finland
Facial pain NOS
5.3
12.8
26
51
M05BX04
ATC
denosumab; parenteral
4.0
12.8
38
102
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.4
12.8
49
157
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
12.8
12.7
22
18
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.9
12.7
67
259
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.7
12.7
42
122
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.3
12.7
112
556
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
33.1
12.6
16
5
L28
ICPC
Limited function/disability (L)
2.6
12.6
85
372
J96.0
ICD-10 Finland
Acute respiratory failure
18.0
12.6
19
11
B01AB04
ATC
dalteparin; parenteral
4.1
12.6
36
94
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
+∞
12.6
12
*
D84.19
ICD-10 Finland
Unspecified defect in the complement system
+∞
12.6
12
*
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
133.5
12.5
13
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.6
12.4
24
45
127
Kela drug reimbursment
Transplant complication
9.4
12.4
25
28
JN6AD
NOMESCO Finland
CT of torso and neck
10.1
12.4
24
25
R53
ICD-10 Finland
Malaise and fatigue
2.2
12.2
130
697
WVA20
NOMESCO Finland
Medicine administration
5.5
12.1
24
46
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
22.0
12.1
17
8
XG474
NOMESCO Finland
Exhalation nntrogen oxide
4.6
12.1
29
66
C08DA01
ATC
verapamil; systemic
4.4
12.0
31
75
N06AA09
ATC
amitriptyline; systemic
2.9
12.0
61
231
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
4.2
11.9
33
84
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.2
11.9
50
169
D70.89
ICD-10 Finland
Neutropenic splenomegaly
12.2
11.9
21
18
M35.7
ICD-10 Finland
Hypermobility syndrome
9.3
11.9
24
27
H02AB02
ATC
dexamethasone; systemic
2.7
11.8
70
287
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.1
11.8
25
51
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.6
11.8
74
313
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
19.6
11.7
17
9
3AC01, ,
NOMESCO Finland
19.6
11.7
17
9
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.7
11.6
70
290
J33.8
ICD-10 Finland
Other polyp of sinus
5.9
11.6
21
37
A46
ICD-10 Finland
Erysipelas
2.6
11.5
71
297
A02BC03
ATC
lansoprazole; oral
2.1
11.5
145
828
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.5
11.4
81
363
N03AX11
ATC
topiramate; oral
4.6
11.3
27
61
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.9
11.3
25
53
R01AD01
ATC
beclometasone; nasal
2.4
11.3
94
453
P01AB01
ATC
metronidazole; oral, rectal
2.0
11.2
208
1360
B29
ICPC
Lymph/immune mech sympt/complt other
25.8
11.2
15
6
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
20.7
11.2
16
8
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.9
11.2
57
216
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.7
11.1
63
252
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
5.9
11.1
20
35
TKC20
NOMESCO Finland
Catheterisation of bladder
3.5
11.1
39
118
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.9
11.1
57
217
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
14.4
11.1
18
13
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.1
11.0
31
80
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.1
11.0
129
715
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
8.6
10.9
23
28
R06AX13
ATC
loratadine; oral
2.4
10.9
90
431
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.4
10.8
41
130
UJD02
NOMESCO Finland
Gastroscopy
3.7
10.8
35
100
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
5.8
10.8
20
36
N02BF02
ATC
pregabalin; oral
3.3
10.7
42
136
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.2
10.7
114
607
A04AA02
ATC
granisetron; systemic, transdermal
3.2
10.7
43
142
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
10.6
129
723
L04AA01
ATC
[U] ciclosporin
10.4
10.6
20
20
A06AD11
ATC
lactulose; oral
2.6
10.6
68
290
P01BA02
ATC
hydroxychloroquine; oral
2.9
10.5
54
205
R51.80
ICD-10 Finland
Headache
2.2
10.5
100
509
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
5.6
10.5
20
37
M81.9
ICD-10 Finland
Osteoporosis, unspecified
4.1
10.5
29
74
GD1DG
NOMESCO Finland
Extremely extensive MRI examination of pleura with high field magnet
112.5
10.5
11
*
D86.2
ICD-10 Finland
Sarcoidosis of lung with sarcoidosis of lymph nodes
+∞
10.5
10
*
D84.1
ICD-10 Finland
Defects in the complement system
+∞
10.5
10
*
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
8.5
10.4
22
27
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
16.5
10.4
16
10
S01AA01
ATC
chloramphenicol; ophthalmic
3.7
10.4
33
93
DHB50
NOMESCO Finland
Turbinoplasty
4.7
10.4
24
53
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.7
10.4
60
243
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.6
10.3
67
287
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
19.3
10.3
15
8
B34.9
ICD-10 Finland
Viral infection, unspecified
4.3
10.3
27
66
B28
ICPC
Limited function/disability (B)
24.0
10.3
14
6
L04AA13
ATC
[U] leflunomide
5.5
10.2
20
38
KA1AE
NOMESCO Finland
Kidney ultrasound examination
5.5
10.2
20
38
R05CB01
ATC
acetylcysteine; inhalant, oral
15.0
10.1
16
11
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
15.0
10.1
16
11
H65.3
ICD-10 Finland
Chronic mucoid otitis media
4.3
10.0
26
63
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
41.0
10.0
12
*
B99
ICPC
Blood/lymph/spleen disease other
41.0
10.0
12
*
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
8.4
9.9
21
26
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
17.2
9.9
15
9
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.7
9.9
59
242
N06AA10
ATC
nortriptyline; systemic
4.6
9.9
24
55
R49.01
ICD-10 Finland
Functional dysphonia
4.2
9.9
27
68
C82.1
ICD-10 Finland
Follicular lymphoma grade II
20.6
9.9
14
7
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
9.9
9.9
19
20
H92.0
ICD-10 Finland
Otalgia
3.1
9.8
43
149
J01.4
ICD-10 Finland
Acute pansinusitis
13.8
9.7
16
12
ZX110
NOMESCO Finland
Intracutaneous
56.2
9.7
11
*
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
56.2
9.7
11
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.7
9.7
31
88
TK800
NOMESCO Finland
Hemodialysis
8.7
9.7
20
24
R96
ICPC
Asthma
2.6
9.6
58
240
WX730
NOMESCO Finland
Conventional respirator
15.5
9.6
15
10
EBA15
NOMESCO Finland
Extraction of multiple teeth
4.0
9.5
27
70
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.7
9.5
55
222
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
102.1
9.4
10
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.8
9.4
51
199
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.6
9.4
58
242
SPAT1262
SPAT
Handing over of treatment supplies
2.2
9.4
85
422
D83.1
ICD-10 Finland
Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
+∞
9.4
9
*
D83.8
ICD-10 Finland
Other common variable immunodeficiencies
+∞
9.4
9
*
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
+∞
9.4
9
*
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
+∞
9.4
9
*
R49.08
ICD-10 Finland
Other specified dysphonia
4.8
9.4
21
45
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.9
9.3
144
873
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
9.3
135
801
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
3.9
9.3
28
76
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.3
9.3
36
116
C03DA01
ATC
spironolactone; oral
2.6
9.2
57
238
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.2
9.2
38
127
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.0
9.2
42
149
N02AC04
ATC
dextropropoxyphene; oral
4.6
9.2
22
50
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.0
9.2
41
144
Z50.5
ICD-10 Finland
Speech therapy
5.2
9.2
19
38
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
4.7
9.2
21
46
J33.0
ICD-10 Finland
Polyp of nasal cavity
4.9
9.1
20
42
M13.9
ICD-10 Finland
Arthritis, unspecified
2.9
9.1
45
167
N17.8
ICD-10 Finland
Other acute renal failure
16.0
9.1
14
9
T78.4
ICD-10 Finland
Allergy, unspecified
3.5
9.1
32
97
C83.1
ICD-10 Finland
Mantle cell lymphoma
37.5
9.1
11
*
R20.2
ICD-10 Finland
Paraesthesia of skin
2.8
9.0
46
174
TPH07
NOMESCO Finland
Cathetrisation of artery
2.6
9.0
57
241
SPAT1255
SPAT
Intravenous administration of medicine
3.3
9.0
35
113
C07AB07
ATC
bisoprolol; oral
1.8
9.0
197
1335
J32.8
ICD-10 Finland
Other chronic sinusitis
19.1
9.0
13
7
WX882
NOMESCO Finland
High dependency care
3.8
9.0
28
78
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
4.6
8.9
21
47
J01DA09
ATC
[U] cefadroxil
2.0
8.9
132
788
XG466
NOMESCO Finland
Sleep oxymetry
4.8
8.9
20
43
A99
ICPC
Disease/condition unspecnature/site
2.6
8.8
52
213
J02AC02
ATC
itraconazole; systemic
2.1
8.8
96
514
A03FA02
ATC
cisapride; oral, rectal
2.9
8.7
41
148
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
14.4
8.7
14
10
X58
ICD-10 Finland
Exposure to other specified factors
2.2
8.7
82
413
H19.3*M35.0
ICD-10 Finland
Keratoconjunctivitis sicca
51.0
8.7
10
*
L03AA13
ATC
pegfilgrastim; parenteral
3.3
8.7
33
105
M05BA07
ATC
risedronic acid; oral
4.9
8.7
19
40
4930B
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA CUM EXACERBATIONE]
16.7
8.6
13
8
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
28.1
8.5
11
*
N07BC02
ATC
methadone; systemic
28.1
8.5
11
*
WW300
NOMESCO Finland
Transfer of autologic stem cells
20.5
8.5
12
6
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.9
8.5
40
145
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
6.9
8.5
20
30
G44.2
ICD-10 Finland
Tension-type headache
2.2
8.4
79
397
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
4.6
8.4
20
45
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
5.0
8.4
18
37
L03AA14
ATC
lipegfilgrastim; parenteral
4.8
8.4
19
41
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.9
8.4
143
891
R42
ICD-10 Finland
Dizziness and giddiness
2.0
8.4
103
574
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.3
8.4
32
102
J01DC02
ATC
cefuroxime; systemic
3.1
8.4
35
118
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.1
8.4
35
118
J01EA01
ATC
trimethoprim; systemic
1.9
8.4
127
762
A12AA04
ATC
calcium carbonate; oral
8.8
8.4
17
20
L04AD02
ATC
tacrolimus; systemic
8.8
8.4
17
20
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.9
8.4
40
146
D84.8
ICD-10 Finland
Other specified immunodeficiencies
+∞
8.4
8
*
J06BA02
ATC
immunoglobulins, normal human, for intravascular adm.; systemic
+∞
8.4
8
*
D81.0
ICD-10 Finland
Severe combined immunodeficiency [SCID] with reticular dysgenesis
+∞
8.4
8
*
D86.1
ICD-10 Finland
Sarcoidosis of lymph nodes
+∞
8.4
8
*
N03AX09
ATC
lamotrigine; oral
3.0
8.3
38
135
E000002, ,
ATC
2.3
8.3
68
323
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
6.7
8.3
20
31
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
3.3
8.3
32
103
B03XA02
ATC
darbepoetin alfa; parenteral
7.8
8.2
18
24
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
7.8
8.2
18
24
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
3.6
8.2
27
78
A07EA06
ATC
budesonide; oral, local oral
3.5
8.2
28
83
B03BA03
ATC
hydroxocobalamin; parenteral
3.5
8.2
28
83
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.3
8.2
64
298
J01.1
ICD-10 Finland
Acute frontal sinusitis
4.9
8.2
18
38
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
4.2
8.2
22
55
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
8.4
8.2
17
21
Z31.5
ICD-10 Finland
Genetic counselling
2.8
8.1
41
154
318
Kela drug reimbursment
Teriparatide
17.6
8.1
12
7
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
34.0
8.1
10
*
N06AX11
ATC
mirtazapine; oral
1.8
8.1
164
1077
H66.9
ICD-10 Finland
Otitis media, unspecified
2.5
8.1
51
215
N06AX17
ATC
milnacipran; oral
10.3
8.1
15
15
DPA30
NOMESCO Finland
Sphenotomy
10.3
8.1
15
15
D50.8
ICD-10 Finland
Other iron deficiency anaemias
10.3
8.1
15
15
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.8
8.0
42
161
J01CA04
ATC
amoxicillin; systemic
2.2
8.0
389
3320
R01BA51
ATC
phenylpropanolamine, combinations; oral
2.3
8.0
65
308
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.1
8.0
22
56
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
4.6
8.0
19
43
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.4
8.0
60
275
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
4.8
7.9
18
39
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
8.0
7.9
17
22
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
3.5
7.9
27
80
RK110, ,
NOMESCO Finland
13.3
7.9
13
10
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
7.9
205
1445
W19
ICD-10 Finland
Unspecified fall
2.4
7.9
55
243
E87.6
ICD-10 Finland
Hypokalaemia
3.9
7.9
23
61
A07EC02
ATC
mesalazine; oral, rectal
3.0
7.9
36
128
K11.2
ICD-10 Finland
Sialoadenitis
4.2
7.9
21
52
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
8.7
7.9
16
19
M01AH01
ATC
celecoxib; oral
2.1
7.8
88
474
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
11.1
7.8
14
13
Z49.1
ICD-10 Finland
Extracorporeal dialysis
11.1
7.8
14
13
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
11.1
7.8
14
13
4224
FHL
Endonasal anthrostomy
9.7
7.8
15
16
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.0
7.8
35
123
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.6
7.8
26
76
4222
FHL
Endonasal etmoidectomy
15.4
7.8
12
8
DPA20
NOMESCO Finland
Trephine of frontal sinus
45.8
7.7
9
*
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.9
7.7
23
62
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
3.9
7.7
23
62
R5140
NOMESCO Finland
Monitoring the use of the aid
2.3
7.7
59
272
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
4.6
7.7
18
40
M48.0
ICD-10 Finland
Spinal stenosis
2.4
7.7
57
259
A03
ICPC
Fever
2.0
7.7
97
545
D02AX
ATC
Other emollients and protectives
3.5
7.6
26
77
J15.8
ICD-10 Finland
Other bacterial pneumonia
18.7
7.6
11
6
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
18.7
7.6
11
6
R2110
NOMESCO Finland
Giving the first information
2.8
7.6
38
142
K07.60
ICD-10 Finland
Snapping jaw
2.8
7.6
38
142
5BA08, ,
NOMESCO Finland
12.1
7.6
13
11
H26.3
ICD-10 Finland
Drug-induced cataract
12.1
7.6
13
11
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
12.1
7.6
13
11
F81.0
ICD-10 Finland
Specific reading disorder
25.5
7.6
10
*
M01AH02
ATC
rofecoxib; oral
2.3
7.6
63
301
C09CA06
ATC
candesartan; oral
1.9
7.6
111
656
Z94.0
ICD-10 Finland
Kidney transplant status
10.3
7.6
14
14
A07AA09
ATC
vancomycin; oral
10.3
7.6
14
14
SXC03
NOMESCO Finland
Other oral or dental procedure
10.3
7.6
14
14
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.4
7.5
19
45
R02
ICPC
Shortness of breath/dyspnoea
2.3
7.5
63
302
L04AD01
ATC
ciclosporin; systemic
4.5
7.5
18
41
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.5
7.5
18
41
A41.8
ICD-10 Finland
Other specified sepsis
6.6
7.5
18
28
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.3
7.5
62
296
XKD00
NOMESCO Finland
Uroflowmetry
2.4
7.5
56
256
M05BB03
ATC
alendronic acid and colecalciferol; oral
6.1
7.5
19
32
C83.00
ICD-10 Finland
Lymphocytic lymphoma
81.4
7.4
8
*
UKC02
NOMESCO Finland
Cystoscopy
2.3
7.4
61
290
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
13.7
7.4
12
9
J32.2
ICD-10 Finland
Chronic ethmoidal sinusitis
13.7
7.4
12
9
WX722
NOMESCO Finland
PEEP
3.2
7.4
29
94
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.1
7.4
79
417
D07AC01
ATC
betamethasone; topical
1.8
7.4
166
1118
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
8.6
7.4
15
18
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
8.6
7.4
15
18
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
7.0
7.4
17
25
J18.1
ICD-10 Finland
Lobar pneumonia, unspecified
11.1
7.3
13
12
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
11.1
7.3
13
12
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
11.1
7.3
13
12
A07EC01
ATC
sulfasalazine; oral, rectal
2.6
7.3
43
175
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.1
7.3
75
390
H65.2
ICD-10 Finland
Chronic serous otitis media
6.4
7.3
18
29
XCK10
NOMESCO Finland
Photography of fundus of eye
2.5
7.3
49
213
UDM02
NOMESCO Finland
Sinoscopy
4.4
7.3
18
42
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
16.1
7.3
11
7
DMB10
NOMESCO Finland
Radical maxillary antrotomy
16.1
7.3
11
7
ZX100
NOMESCO Finland
Oral
7.5
7.2
16
22
J37.0
ICD-10 Finland
Chronic laryngitis
3.7
7.2
23
65
R4130
NOMESCO Finland
Speech therapy
4.1
7.2
20
51
B81
ICPC
Anaemia vit B12/folate deficiency
4.1
7.2
20
51
XKD06
NOMESCO Finland
Physiologic investigation of micturition
4.1
7.2
20
51
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.3
7.2
56
260
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
3.2
7.2
29
96
A02BA03
ATC
famotidine; systemic
3.9
7.2
21
56
TK810
NOMESCO Finland
Hemofiltration
20.4
7.2
10
5
RS222, ,
NOMESCO Finland
8.1
7.2
15
19
XG405
NOMESCO Finland
Education on PEF monitoring
8.1
7.2
15
19
R60.0
ICD-10 Finland
Localized oedema
2.3
7.1
56
261
SPAT1229
SPAT
Assessment of need for aid
2.9
7.1
34
124
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.9
7.1
34
124
N02BE01
ATC
paracetamol; systemic, rectal
2.2
7.1
399
3480
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
12.3
7.1
12
10
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.6
7.1
23
66
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
10.3
7.1
13
13
M01CB01
ATC
sodium aurothiomalate; parenteral
10.3
7.1
13
13
RS224, ,
NOMESCO Finland
10.3
7.1
13
13
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.3
7.1
18
43
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.6
7.1
41
166
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.6
7.1
40
160
E000001, ,
ATC
1.9
7.0
99
576
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.2
7.0
62
304
N30.9
ICD-10 Finland
Cystitis, unspecified
2.8
7.0
36
137
D07AD01
ATC
clobetasol; topical
2.0
7.0
79
426
K50.8
ICD-10 Finland
Other Crohn disease
6.0
7.0
18
31
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.6
7.0
41
167
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
3.7
7.0
22
62
H05AA02
ATC
teriparatide; parenteral
14.0
6.9
11
8
J05AH02
ATC
oseltamivir; oral
14.0
6.9
11
8
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
14.0
6.9
11
8
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.1
6.9
28
93
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
3.9
6.9
20
53
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
8.5
6.9
14
17
R05
ICPC
Cough
1.8
6.9
126
797
R01BA01
ATC
phenylpropanolamine; oral
2.9
6.9
33
121
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
6.3
6.8
17
28
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.7
6.8
21
58
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
9.5
6.8
13
14
602
Kela drug reimbursment
Children's severe malnutrition
9.5
6.8
13
14
J01.9
ICD-10 Finland
Acute sinusitis, unspecified
3.1
6.8
29
99
R52.0
ICD-10 Finland
Acute pain
3.3
6.8
25
78
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.5
6.8
23
68
F43.29
ICD-10 Finland
Adaptation disorder UNS
4.0
6.8
19
49
M30.1
ICD-10 Finland
Polyarteritis with lung involvement [Churg-Strauss]
40.7
6.8
8
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
40.7
6.8
8
*
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
17.0
6.8
10
6
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
17.0
6.8
10
6
R74
ICPC
Upper respiratory infection acute
1.7
6.8
174
1211
J34.2
ICD-10 Finland
Deviated nasal septum
2.8
6.8
33
122
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.8
6.8
33
122
R5599
NOMESCO Finland
Other rehabilitation service
3.8
6.7
20
54
A10AB05
ATC
insulin aspart; parenteral
2.5
6.7
43
183
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
22.9
6.7
9
*
ELA30
NOMESCO Finland
Biopsy of salivary gland
22.9
6.7
9
*
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
22.9
6.7
9
*
RS220, ,
NOMESCO Finland
5.6
6.7
18
33
R01AC01
ATC
cromoglicic acid; nasal
3.1
6.7
28
95
WX204
NOMESCO Finland
Axillary plexus blockaced
3.4
6.6
24
74
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
6.6
46
203
J20.5
ICD-10 Finland
Acute bronchitis due to respiratory syncytial virus
12.5
6.6
11
9
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
6.6
103
619
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
3.9
6.6
19
50
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
7.0
6.6
15
22
B01AB05
ATC
enoxaparin; parenteral
1.8
6.5
136
891
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
6.3
6.5
16
26
B99
ICD-10 Finland
Other and unspecified infectious diseases
5.8
6.5
17
30
A10AC01
ATC
insulin (human); parenteral
2.5
6.5
40
167
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.9
6.4
30
108
YNB10
NOMESCO Finland
Collection of stem cells for transplant
70.8
6.4
7
*
4AA24, ,
NOMESCO Finland
70.8
6.4
7
*
J02AC04
ATC
posaconazole; systemic
70.8
6.4
7
*
R06AX26
ATC
fexofenadine; oral
2.4
6.4
44
193
N30.0
ICD-10 Finland
Acute cystitis
2.0
6.4
76
416
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.8
6.4
19
51
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
14.6
6.4
10
7
K12.10
ICD-10 Finland
Stomatitis NOS
14.6
6.4
10
7
X57
ICD-10 Finland
Unspecified privation
4.2
6.4
17
42
M03BX01
ATC
baclofen; systemic
5.3
6.4
18
35
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.7
6.4
35
138
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
6.4
57
281
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.5
6.4
41
175
F45.8
ICD-10 Finland
Other somatoform disorders
2.5
6.4
41
175
EB1WA, ,
NOMESCO Finland
11.2
6.3
11
10
RK320, ,
NOMESCO Finland
11.2
6.3
11
10
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
9.4
6.3
12
13
RS230, ,
NOMESCO Finland
9.4
6.3
12
13
RS121, ,
NOMESCO Finland
9.4
6.3
12
13
N03AX14
ATC
levetiracetam; systemic
3.9
6.3
18
47
XX3DW
NOMESCO Finland
Time consuming IT work
2.2
6.3
55
268
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
18.3
6.3
9
5
SPAT1324
SPAT
Screening procedure
0.3
6.3
21
580
C81.0
ICD-10 Finland
Nodular lymphocyte predominant Hodgkin lymphoma
+∞
6.3
6
*
4732A
ICD-9 Finland
Chronic sinusitis, Ethmoidal
+∞
6.3
6
*
D80.5
ICD-10 Finland
Immunodeficiency with increased immunoglobulin M [IgM]
+∞
6.3
6
*
2AA01, ,
NOMESCO Finland
+∞
6.3
6
*
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
+∞
6.3
6
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
6.3
202
1485
5AB14, ,
NOMESCO Finland
27.1
6.2
8
*
GD1CG
NOMESCO Finland
Extensive examination of lungs and pleura with high intensity magnet
27.1
6.2
8
*
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
27.1
6.2
8
*
N02CC03
ATC
zolmitriptan; nasal, oral
2.6
6.2
37
152
L88
ICPC
Rheumatoid/seropositive arthritis
3.2
6.1
24
78
M79.6
ICD-10 Finland
Pain in limb
1.6
6.1
194
1417
M25.5
ICD-10 Finland
Pain in joint
1.7
6.1
154
1060
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
12.7
6.1
10
8
J05AB09
ATC
famciclovir; oral
12.7
6.1
10
8
ZXD35
NOMESCO Finland
Usual procedure
3.7
6.1
19
53
GBB00
NOMESCO Finland
Tracheostomy
8.8
6.1
12
14
PJA10
NOMESCO Finland
Exploration of lymph nodes
6.8
6.1
14
21
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
6.8
6.1
14
21
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.7
6.1
138
924
B03XA01
ATC
erythropoietin; parenteral
10.2
6.1
11
11
D06AX01
ATC
fusidic acid; topical
2.2
6.1
51
245
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.8
6.1
119
765
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
5.7
6.0
16
29
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
6.2
6.0
15
25
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.4
6.0
40
173
N05CF02
ATC
zolpidem; oral
1.9
6.0
86
502

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
167
26
100.77
315.82
3.0
1.7
39.05
39.39
%
0.05
159
26
189
31
103.42
307.65
3.0
1.4
1.35
1.55
e9/l
0.44
162
24
318
255
38.90
307.65
5.1
1.6
0.81
1.46
g/l
3.55
297
238
137
27
72.10
246.49
2.9
1.3
580.55
712.35
e6/l
0.41
107
20
146
39
54.60
245.81
2.2
1.4
1.74
2.70
g/l
2.24
119
28
146
39
54.60
245.81
2.3
1.4
—
—
—
0
0
146
39
54.60
245.81
2.2
1.4
4.49
6.55
g/l
4.10
121
29
146
39
54.60
245.81
2.2
1.4
0.24
0.33
g/l
1.08
120
29
134
26
72.57
241.65
2.9
1.3
0.22
0.19
e9/l
0.38
108
20
149
64
34.10
216.43
2.2
1.4
0.27
0.72
g/l
4.06
121
54
107
16
87.07
200.54
2.9
1.8
735.71
340.00
e6/l
—
77
6
194
264
12.05
147.11
2.0
1.2
49.91
219.60
u/ml
1.23
149
242
334
900
11.13
139.82
5.2
1.4
1.24
2.24
g/l
20.57
275
560
120
139
11.36
99.92
1.8
1.6
0.23
0.23
g/l
0.15
108
134
122
147
10.97
98.63
1.8
1.5
1.15
1.19
g/l
0.53
113
141
78
45
20.70
97.73
4.0
3.1
—
—
—
0
0
86
0
+∞
92.96
1.5
0.0
—
—
—
0
0
404
1808
11.83
88.46
24.0
6.4
—
—
—
0
0
413
1913
13.29
86.53
22.9
5.9
0.58
0.56
e9/l
0.57
403
1649
413
1917
13.24
86.21
22.9
5.9
0.04
0.04
e9/l
0.21
403
1652
414
1965
13.02
83.11
23.1
5.9
2.01
2.00
e9/l
0.02
408
1737
413
1973
12.59
81.73
24.7
6.4
0.17
0.19
e9/l
2.03
408
1731
275
950
5.77
76.90
19.1
6.9
—
—
—
0
0
133
246
7.22
73.45
4.4
2.7
61.38
67.14
g/l
10.37
128
227
247
826
5.34
70.47
10.3
4.0
—
—
—
0
0
414
2219
10.40
65.03
32.6
9.3
3.88
3.97
e9/l
0.40
409
1930
46
22
23.14
61.88
2.8
2.1
37.21
45.44
%
—
24
9
110
202
6.86
60.43
4.0
2.3
—
—
—
0
0
61
5
140.42
58.42
3.0
1.8
—
—
—
0
0
352
1732
5.53
57.95
30.1
8.9
0.00
0.00
e9/l
0.11
326
1390
171
505
4.82
54.71
3.1
2.0
—
—
—
0
0
158
438
4.99
54.70
2.5
1.7
—
—
—
0
0
160
455
4.88
53.54
4.0
2.2
22.67
23.59
%
0.24
152
394
154
446
4.70
49.98
2.6
1.4
—
—
—
0
0
250
1033
4.14
49.85
10.0
3.7
7.40
7.40
ph
0.41
56
194
316
1571
4.29
47.52
21.8
6.3
1.21
1.22
mmol/l
2.87
307
1442
217
842
4.01
46.72
3.1
2.1
2.92
3.02
mg/l
0.26
206
718
310
1550
4.12
45.52
4.7
2.4
83.26
75.96
nmol/l
4.13
302
1399
72
113
7.38
45.35
2.8
3.2
—
—
—
0
0
204
777
3.94
44.76
2.3
1.9
—
—
—
0
0
232
968
3.84
44.37
6.2
3.0
—
—
—
0
0
107
255
5.18
43.61
5.9
2.9
74.50
75.03
e9/l
0.04
77
185
135
389
4.51
43.49
2.9
1.4
—
—
—
0
0
232
978
3.79
43.49
6.3
3.1
0.17
0.46
e6/l
2.49
195
731
46
43
11.79
43.30
2.1
1.2
—
—
—
0
0
70
112
7.20
43.25
1.3
1.2
—
—
—
0
0
130
366
4.57
43.13
7.5
3.1
1.93
1.74
%
1.02
122
339
51
56
10.13
42.95
1.7
1.9
—
—
—
0
0
321
1719
3.93
40.82
21.4
7.0
1.21
1.22
mmol/l
1.04
285
1477
161
553
3.95
40.44
14.0
4.2
0.81
0.82
mmol/l
0.21
156
523
186
709
3.74
39.98
5.7
2.8
506.19
543.46
mosm/kgh2o
1.62
174
613
47
51
10.16
39.87
2.3
1.7
—
—
—
0
0
267
1286
3.60
39.71
7.5
3.7
22.96
61.51
e6/l
2.34
207
888
67
112
6.84
39.63
5.3
2.3
6.60
10.11
g/l
8.85
61
104
56
77
8.15
39.46
7.4
4.3
35.06
139.03
mg/l
0.66
40
61
56
77
8.15
39.46
7.4
4.3
18.64
26.52
mg/l
1.16
41
60
127
376
4.30
39.10
3.4
2.0
313.07
363.55
nmol/l
1.84
118
354
62
98
7.16
38.62
5.0
2.4
38.74
38.92
g/l
0.08
57
91
188
737
3.64
38.46
5.5
2.6
3.96
5.35
e6/l
1.48
176
661
236
1072
3.49
38.15
6.5
3.2
21.53
62.66
e6/l
1.78
197
817
286
1466
3.55
37.94
12.7
4.7
34.71
36.42
g/l
5.10
280
1388
330
1873
3.76
36.72
12.9
6.4
9.89
10.82
umol/l
0.89
324
1771
149
525
3.73
35.46
2.6
2.4
148.70
126.03
ug/g
0.26
125
416
35
29
12.99
35.41
1.6
1.2
0.28
0.26
u/ml
0.05
26
13
45
55
8.97
34.81
7.4
5.0
—
—
—
0
0
417
2839
6.48
34.59
22.8
7.2
83.92
80.61
u/l
0.82
411
2661
414
2808
6.15
34.35
13.8
4.0
12.93
10.62
mm/h
2.43
409
2590
104
291
4.33
34.18
9.3
4.5
0.75
0.55
%
0.52
54
103
106
310
4.15
32.73
10.5
4.7
1.18
0.86
%
0.56
56
121
102
290
4.24
32.72
10.5
4.9
0.25
0.09
%
0.88
53
100
63
120
5.93
32.53
2.7
2.6
1.34
1.45
g/l
0.30
53
105
99
280
4.24
31.94
10.5
4.9
0.41
0.03
%
0.50
49
88
48
73
7.23
30.81
7.8
3.7
57.10
55.79
%
0.22
48
73
122
420
3.60
29.51
4.1
3.5
6.02
6.96
umol/l
0.33
111
362
100
302
3.96
29.32
23.9
8.6
—
—
—
0
0
292
1684
3.04
28.61
5.3
2.7
203.68
98.92
ug/l
2.32
284
1561
92
267
4.06
28.47
23.5
7.8
1.26
1.31
mmol/l
0.18
87
259
248
1338
2.87
27.00
2.6
1.9
96.23
97.29
pmol/l
0.13
153
682
43
67
6.98
26.93
3.0
2.0
126.76
130.89
g/l
0.25
17
47
130
493
3.29
26.70
2.0
1.5
—
—
—
0
0
137
548
3.14
25.60
1.7
1.4
555.00
476.00
titre
0.23
24
120
151
639
3.04
25.57
2.0
1.6
—
—
—
0
0
51
100
5.62
25.39
1.2
1.2
—
—
—
0
0
177
822
2.88
25.24
3.6
1.9
1.57
1.08
mg/l
0.53
147
630
324
2083
2.92
24.11
15.0
4.8
6.58
6.55
mmol/l
0.09
313
1935
132
549
2.98
22.72
4.4
2.9
2.75
2.54
e6/l
0.08
69
289
136
580
2.92
22.32
4.2
2.8
1.59
0.88
e6/l
1.11
72
319
92
313
3.43
22.20
1.5
1.4
—
—
—
0
0
26
29
9.45
21.39
1.5
1.2
—
—
—
0
0
89
306
3.37
21.05
2.3
1.4
—
—
—
0
0
161
770
2.69
21.03
2.0
1.4
23.38
21.60
nmol/l
0.51
150
651
172
856
2.62
20.66
4.9
2.9
1431.64
910.01
ng/l
0.86
160
706
74
230
3.65
20.43
1.7
1.3
—
—
—
0
0
120
502
2.89
20.19
1.3
1.2
—
—
—
0
0
358
2552
2.87
19.65
8.4
4.1
—
—
—
0
0
39
77
5.45
19.18
2.1
1.4
85.21
110.37
u/ml
—
7
10
100
389
3.01
19.10
21.0
7.2
104.25
104.10
mmol/l
0.12
100
389
29
45
6.81
18.14
3.7
2.7
—
—
—
0
0
88
330
3.07
17.85
16.7
9.8
0.97
1.31
mmol/l
0.31
71
263
24
31
8.12
17.58
1.3
1.2
—
—
—
0
0
89
340
3.01
17.45
2.7
2.5
30.18
33.54
u/l
0.29
71
287
39
84
4.98
17.38
2.2
1.5
—
—
—
0
0
78
278
3.18
17.22
1.7
1.4
—
—
—
0
0
25
35
7.50
17.12
3.0
3.6
—
—
—
0
0
159
822
2.43
17.04
4.5
3.4
—
—
—
0
0
29
23
13.38
16.88
2.1
1.4
—
—
—
0
0
87
336
2.96
16.69
23.1
4.7
1.75
2.04
mmol/l
0.33
80
268
199
1143
2.31
16.68
5.4
2.2
—
—
—
0
0
169
906
2.37
16.61
7.5
2.7
321.17
5473.48
umol/l
3.08
155
796
31
58
5.66
16.12
1.6
1.2
—
—
—
0
0
26
41
6.66
16.00
1.8
1.1
—
—
—
0
0
204
1200
2.27
15.98
5.6
3.3
2.33
2.36
mmol/l
2.94
184
1065
239
1507
2.23
15.71
4.5
3.2
5.84
5.85
ph
0.01
19
139
184
1043
2.28
15.70
3.5
2.1
110.41
184.04
u/l
2.00
177
983
30
56
5.66
15.63
1.4
1.8
—
—
—
0
0
273
1833
2.22
15.14
8.0
4.8
0.00
0.00
estimate
-0.00
75
363
234
1484
2.18
14.91
13.2
10.3
1.11
1.18
inr
0.59
67
474
25
19
13.85
14.87
2.5
3.5
28.08
29.37
umol/l
0.16
25
19
124
611
2.41
14.46
5.0
3.3
103.02
231.69
ng/l
1.13
87
433
95
413
2.64
14.44
1.5
1.3
—
—
—
0
0
273
1858
2.17
14.30
5.9
3.5
0.00
0.01
estimate
0.50
73
349
270
1836
2.15
14.09
6.0
3.4
0.00
0.00
estimate
0.50
76
376
43
118
3.92
14.09
1.6
1.4
365.76
311.25
ug/g
0.89
25
69
155
859
2.22
13.60
5.0
2.1
—
—
—
0
0
50
157
3.45
13.45
22.7
13.4
—
—
—
0
0
49
153
3.47
13.29
1.9
1.4
—
—
—
0
0
39
104
4.01
13.28
3.8
2.0
208.45
279.49
ug/l
0.36
33
96
178
1054
2.13
13.11
4.4
2.7
—
—
—
0
0
12
0
+∞
12.55
1.8
0.0
—
—
—
0
0
57
204
3.05
12.37
4.4
2.8
240.82
159.88
ng/l
0.40
49
187
31
74
4.42
12.19
3.7
1.5
—
—
—
0
0
112
565
2.30
12.16
1.9
1.7
1298.97
1219.93
nmol/l
0.34
97
423
227
1507
2.01
11.94
2.7
2.0
—
—
—
0
0
19
13
15.19
11.89
1.4
1.7
—
—
—
0
0
35
94
3.95
11.80
2.2
1.4
141.12
234.73
u/ml
1.54
25
49
440
3848
5.09
11.37
51.9
12.1
18.73
21.11
mg/l
1.23
418
2938
42
134
3.35
11.00
3.9
5.3
0.20
0.32
g/l
0.51
26
59
20
36
5.76
10.79
3.8
2.0
—
—
—
0
0
44
147
3.21
10.70
1.6
1.2
0.48
1.13
u/ml
—
6
10
23
30
8.01
10.51
3.1
1.7
—
—
—
0
0
16
10
16.52
10.42
2.3
1.4
—
—
—
0
0
23
49
4.89
10.35
3.2
1.9
1.61
1.59
mmol/l
0.04
23
49
21
26
8.41
9.94
3.1
4.1
—
—
—
0
0
19
36
5.46
9.72
1.2
1.2
—
—
—
0
0
21
44
4.95
9.63
3.0
3.3
51.33
50.72
u/ml
—
6
11
25
61
4.28
9.56
5.8
2.5
16.17
16.26
%
0.03
15
27
30
84
3.75
9.54
4.0
1.4
11.29
6.07
e6/l
0.30
24
69
30
84
3.75
9.54
4.0
1.5
62.04
284.85
e6/l
1.33
24
71
405
3450
2.55
9.51
56.1
14.8
14.65
14.60
%
0.07
405
3403
40
136
3.13
9.45
1.4
1.2
—
—
—
0
0
28
77
3.81
9.14
1.3
1.2
—
—
—
0
0
109
604
2.06
9.09
3.4
2.6
2.45
2.45
mmol/l
0.15
96
531
22
51
4.48
8.96
7.1
3.3
—
—
—
0
0
21
47
4.64
8.92
1.4
1.3
—
—
—
0
0
37
125
3.13
8.84
1.4
1.2
2.74
3.15
u/ml
—
5
13
19
40
4.91
8.66
2.6
1.9
90.23
89.74
%
0.14
19
40
41
150
2.90
8.54
1.3
1.2
—
—
—
0
0
27
76
3.71
8.53
37.2
3.5
—
—
—
0
0
42
156
2.86
8.51
25.9
3.1
0.56
0.64
%
1.12
42
156
47
186
2.70
8.46
8.1
7.5
—
—
—
0
0
14
11
13.08
8.42
2.6
1.6
—
—
—
0
0
24
64
3.90
8.17
8.6
2.4
—
—
—
0
0
14
12
11.99
8.12
2.1
1.7
—
—
—
0
0
12
7
17.56
8.11
3.0
2.7
—
—
—
0
0
21
51
4.27
8.08
2.9
2.5
—
—
—
0
0
22
56
4.08
7.97
1.1
1.1
—
—
—
0
0
19
43
4.57
7.97
5.1
1.7
—
—
—
0
0
18
26
7.16
7.84
4.7
1.9
—
—
—
0
0
23
62
3.85
7.72
1.9
1.4
—
—
—
0
0
24
67
3.73
7.68
7.5
2.8
2.32
2.98
mmol/l
0.55
18
44
59
274
2.32
7.59
15.3
4.0
7.42
7.41
ph
0.83
13
23
21
55
3.95
7.33
5.0
3.4
—
—
—
0
0
16
22
7.49
7.25
2.4
2.7
78.69
120.25
ug/l
0.52
16
22
315
2543
1.77
7.24
4.7
3.4
—
—
—
0
0
114
690
1.87
7.20
1.3
1.3
27.78
35.86
iu/ml
0.42
31
223
228
1692
1.70
7.06
5.4
2.5
—
—
—
0
0
17
39
4.49
7.02
4.2
1.8
32.82
32.72
pg
0.03
17
39
41
167
2.60
6.98
2.5
2.4
—
—
—
0
0
15
20
7.71
6.95
1.5
1.9
10.61
10.77
umol/l
0.04
15
20
23
68
3.51
6.78
1.1
1.1
—
—
—
0
0
12
12
10.23
6.57
4.4
2.2
—
—
—
0
0
16
26
6.34
6.52
1.3
1.2
—
—
—
0
0
23
70
3.41
6.50
1.2
1.1
—
—
—
0
0
179
1268
1.68
6.45
5.0
3.2
24.19
29.45
ng/l
0.44
123
794
13
16
8.33
6.37
1.2
1.1
958.38
1648.63
miu/ml
1.23
13
16
67
354
2.05
6.24
1.2
1.2
—
—
—
0
0
23
72
3.31
6.23
5.7
2.0
—
—
—
0
0
17
43
4.07
6.22
2.1
1.3
—
—
—
0
0
21
62
3.50
6.21
1.2
1.3
1.71
3.48
u/ml
—
7
27
24
78
3.19
6.13
1.3
1.1
—
—
—
0
0
24
78
3.19
6.13
1.3
1.1
—
—
—
0
0
34
137
2.60
5.93
2.4
1.7
9.97
9.78
u/l
0.02
29
109
15
26
5.93
5.88
1.3
1.0
—
—
—
0
0
81
472
1.87
5.67
1.4
1.2
—
—
—
0
0
9
7
13.08
5.60
1.2
2.1
—
—
—
0
0
10
10
10.19
5.55
1.2
1.1
—
—
—
0
0
15
461
0.30
5.49
1.2
1.4
—
—
—
0
0
8
5
16.24
5.43
8.1
6.6
—
—
—
0
0
48
237
2.15
5.33
3.2
2.8
4.00
6.38
e9/l
0.75
39
201
60
323
1.99
5.30
8.8
3.5
—
—
—
0
0
71
408
1.88
5.18
1.7
1.7
—
—
—
0
0
145
1019
1.62
5.17
1.4
1.4
0.45
1.70
u/ml
3.63
24
286
142
993
1.62
5.16
7.1
3.6
0.00
0.00
estimate
-0.00
71
356
14
27
5.31
5.12
4.4
1.6
—
—
—
0
0
103
667
1.70
5.02
1.3
1.3
6.95
10.31
u/ml
0.25
23
264
33
143
2.41
4.97
1.3
1.3
217.93
249.53
miu/ml
0.20
15
72
29
119
2.53
4.90
7.3
5.3
—
—
—
0
0
16
38
4.33
4.87
1.3
1.1
—
—
—
0
0
9
10
9.15
4.80
1.0
1.6
—
—
—
0
0
13
25
5.32
4.80
2.8
2.5
1.14
1.28
g/24h
—
8
14
17
52
3.36
4.79
1.1
1.3
—
—
—
0
0
17
53
3.29
4.66
1.8
1.6
—
—
—
0
0
16
49
3.35
4.51
1.0
1.3
—
—
nmol/l
—
0
0
11
19
5.90
4.46
1.0
1.3
—
—
—
0
0
9
12
7.62
4.37
1.9
1.2
—
—
—
0
0
140
1011
1.56
4.33
1.7
1.7
1.45
1.39
mmol/l
0.39
131
864
10
16
6.36
4.31
1.1
1.1
—
—
—
0
0
150
1105
1.53
4.23
4.7
3.3
6.45
7.72
mmol/l
3.21
139
947
344
3019
1.57
4.10
5.2
4.1
14.81
14.61
pmol/l
0.78
331
2771
433
4055
2.34
4.05
31.4
11.3
—
—
—
0
0
11
22
5.10
4.02
2.1
1.5
—
—
—
0
0
11
22
5.10
4.02
1.0
1.0
—
—
—
0
0
10
18
5.65
3.99
1.2
1.1
—
—
—
0
0
17
59
2.95
3.94
1.9
1.8
—
—
—
0
0
102
701
1.59
3.87
2.0
1.7
505.23
447.73
pmol/l
1.08
96
577
6
5
12.13
3.77
1.8
1.0
—
—
—
0
0
6
5
12.13
3.77
2.0
1.2
16.97
16.28
umol/l
—
6
5
6
5
12.13
3.77
1.8
1.0
—
—
—
0
0
6
5
12.13
3.77
1.8
1.0
—
—
—
0
0
9
16
5.71
3.67
1.1
1.1
117.11
191.54
mmol/24h
—
9
16
9
16
5.71
3.67
1.3
1.2
—
—
—
0
0
7
9
7.88
3.57
5.0
2.3
—
—
—
0
0
7
9
7.88
3.57
1.7
1.0
—
—
—
0
0
106
1442
0.65
3.56
2.7
2.8
—
—
—
0
0
8
13
6.24
3.51
5.3
4.2
31.06
47.73
%
—
8
13
6
6
10.11
3.50
3.2
1.3
—
—
—
0
0
6
6
10.11
3.50
1.0
1.0
4.92
4.55
mg/g
—
6
6
35
182
2.00
3.44
1.1
1.1
—
—
—
0
0
7
10
7.09
3.37
1.1
1.1
—
—
—
0
0
8
14
5.79
3.35
2.4
3.4
—
—
—
0
0
139
1051
1.46
3.33
6.2
3.1
—
—
—
0
0
12
33
3.71
3.31
47.7
4.0
9.76
12.06
%
1.44
12
33
387
3545
1.61
3.28
6.1
4.8
1.83
2.19
mu/l
0.53
377
3284
8
15
5.41
3.20
1.3
1.5
123.87
154.67
nmol/l
—
8
15
7
11
6.44
3.19
1.0
1.0
—
—
—
0
0
36
196
1.91
3.12
21.3
4.3
24.12
24.53
mmol/l
0.41
36
189
299
2615
1.42
3.08
5.3
3.2
61.51
43.38
u/l
2.33
290
2467
8
16
5.07
3.06
2.1
1.8
—
—
—
0
0
8
16
5.07
3.06
2.4
1.3
61.50
88.27
mg/l
—
8
11
14
51
2.80
3.01
2.7
1.3
16.04
3.40
ug/l
0.65
14
42
10
26
3.91
2.99
1.7
1.8
0.86
0.99
g/l
—
10
26
126
958
1.44
2.89
4.8
3.2
1497.43
344.65
mg/l
0.81
81
607
12
38
3.22
2.87
4.3
2.8
12.98
14.55
mu/l
0.21
12
38
9
23
3.97
2.79
2.6
1.8
—
—
—
0
0
41
242
1.76
2.78
1.1
1.2
—
37.63
—
0
8
5
6
8.41
2.75
1.2
3.3
—
—
—
0
0
9
24
3.80
2.68
1.7
1.4
—
—
—
0
0
8
20
4.05
2.58
1.6
1.5
1.81
1.55
g/l
—
8
20
37
217
1.77
2.57
20.9
4.2
—
—
—
0
0
6
11
5.51
2.55
1.0
1.0
0.00
1.07
u/ml
—
6
11
27
145
1.92
2.47
2.7
1.6
—
—
—
0
0
16
70
2.33
2.44
2.1
1.1
50.50
31.28
iu/ml
—
6
18
6
12
5.05
2.41
1.0
1.3
—
—
—
0
0
5
8
6.30
2.37
1.6
1.4
—
—
—
0
0
14
62
2.30
2.09
3.5
1.8
5.73
4.70
mmol/24h
0.69
14
52
10
37
2.74
2.08
1.2
1.3
—
—
—
0
0
5
10
5.04
2.07
1.0
3.8
23.28
17.25
mmol/l
—
5
10
22
118
1.91
2.05
17.7
9.1
—
—
—
0
0
8
26
3.11
2.02
1.3
1.3
—
—
—
0
0
7
21
3.37
1.97
5.0
6.1
—
—
—
0
0
130
1054
1.33
1.94
1.8
1.4
—
—
—
0
0
12
52
2.34
1.89
1.2
1.0
—
—
—
0
0
124
1003
1.32
1.88
6.0
3.8
23.24
8.79
mg/mmol
1.43
79
618
6
17
3.56
1.84
1.3
1.1
—
—
—
0
0
6
17
3.56
1.84
2.7
3.1
48133.33
35923.82
ug/l
—
6
17
13
61
2.16
1.73
2.6
1.4
—
—
—
0
0
5
13
3.88
1.72
1.2
1.4
42.20
54.46
nmol/24h
—
5
13
25
150
1.71
1.67
1.8
1.5
286.52
282.75
mu/l
0.04
25
138
8
31
2.61
1.66
1.1
1.1
—
—
—
0
0
5
14
3.60
1.62
1.2
1.1
—
—
—
0
0
8
32
2.53
1.60
1.1
1.8
—
—
—
0
0
12
58
2.10
1.50
1.2
1.2
—
—
—
0
0
29
434
0.65
1.49
1.9
1.7
—
—
—
0
0
15
80
1.90
1.46
1.3
1.2
—
—
—
0
0
7
29
2.44
1.39
1.0
1.0
—
—
—
0
0
5
18
2.80
1.29
1.8
1.5
—
—
—
0
0
45
333
1.39
1.23
4.0
4.0
35.08
20.80
ug/l
0.16
38
272
27
181
1.52
1.21
1.1
1.1
—
—
—
0
0
42
316
1.36
1.06
1.9
1.2
94.44
153.71
iu/ml
0.74
17
135
9
46
1.98
1.04
1.1
1.4
—
—
—
0
0
442
4334
1.65
1.04
65.3
18.1
249.22
256.04
e9/l
1.07
442
4224
442
4335
1.64
1.02
68.2
18.2
39.32
40.53
%
5.87
432
4109
442
4336
1.63
1.00
65.0
18.0
90.46
90.36
fl
0.15
442
4280
442
4336
1.63
1.00
64.9
18.0
29.95
30.14
pg
1.23
442
4279
33
241
1.40
1.00
2.3
2.2
6.23
5.80
ug/l
0.08
28
212
442
4337
1.62
0.99
65.2
18.1
6.92
6.59
e9/l
1.00
442
4218
442
4337
1.62
0.99
65.2
18.1
4.40
4.53
e12/l
5.44
442
4221
15
92
1.65
0.98
1.2
1.3
—
—
—
0
0
442
4339
1.61
0.96
65.7
18.2
129.90
135.99
g/l
13.07
442
4283
61
496
1.27
0.91
1.9
1.6
—
—
—
0
0
355
3408
1.19
0.80
6.2
5.3
39.06
39.11
mmol/mol
0.03
341
3199
0
25
0.00
0.79
0.0
1.1
—
—
—
0
0
0
27
0.00
0.77
0.0
1.3
—
—
—
0
0
54
443
1.25
0.77
2.5
2.8
0.53
0.72
ug/l
2.77
39
267
34
264
1.31
0.74
6.6
3.4
—
—
—
0
0
16
109
1.48
0.72
2.6
2.4
—
—
—
0
0
363
3738
0.86
0.63
4.8
4.2
4.71
4.77
mmol/l
0.47
350
3504
348
3588
0.87
0.58
4.5
3.8
1.38
1.27
mmol/l
2.03
335
3332
11
73
1.52
0.56
3.5
2.4
—
—
—
0
0
20
152
1.33
0.53
1.8
2.2
303.60
4042.27
u/l
—
5
57
9
64
1.41
0.51
1.1
1.1
—
—
—
0
0
21
264
0.79
0.46
1.6
1.4
—
—
—
0
0
5
85
0.58
0.45
13.0
4.4
—
—
—
0
0
31
257
1.22
0.44
1.1
1.2
—
—
—
0
0
364
3719
0.89
0.40
4.7
4.2
1.47
1.50
mmol/l
0.44
346
3470
0
18
0.00
0.40
0.0
1.1
—
7.05
—
0
18
5
35
1.43
0.39
1.8
1.0
—
—
—
0
0
13
99
1.32
0.36
1.3
2.5
—
—
—
0
0
16
130
1.24
0.29
1.4
2.9
—
—
—
0
0
9
119
0.75
0.27
1.2
1.3
—
—
—
0
0
87
815
1.08
0.25
5.7
3.5
1.02
1.02
kg/l
—
7
110
373
3784
0.92
0.25
5.2
4.6
2.75
2.85
mmol/l
1.20
357
3527
23
200
1.16
0.23
1.2
2.0
—
—
—
0
0
23
200
1.16
0.23
1.2
2.0
—
—
—
0
0
23
200
1.16
0.23
1.2
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
6.3
—
—
—
0
0
5
43
1.16
0.21
2.8
2.7
4.22
3.93
mmol/l
—
5
43
5
43
1.16
0.21
2.8
2.7
106.00
105.16
mmol/l
—
5
43
21
240
0.87
0.21
2.6
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
2.1
—
—
—
0
0
18
155
1.17
0.20
1.2
2.1
—
—
—
0
0
17
149
1.15
0.16
1.5
1.6
—
—
—
0
0
22
200
1.11
0.12
1.2
1.8
—
—
—
0
0
23
211
1.09
0.11
3.8
2.3
—
—
—
0
0
17
154
1.11
0.10
6.8
3.5
—
—
—
0
0
20
184
1.09
0.09
1.2
2.0
—
—
—
0
0
9
85
1.06
0.07
1.2
1.4
—
—
—
0
0
9
85
1.06
0.07
1.2
1.4
—
—
—
0
0
9
86
1.05
0.07
1.2
1.1
—
—
—
0
0
9
87
1.04
0.07
1.3
1.5
—
—
—
0
0
96
970
0.99
0.02
4.6
3.6
—
—
—
0
0
361
3617
0.99
0.01
4.8
4.2
5.89
5.83
mmol/l
0.41
351
3334
32
319
1.00
0.00
9.3
4.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
34.26
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
73
0.96
-0.00
1.7
5.0
314.57
371.52
umol/l
—
7
65
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint D3_IMMUDEFANTIBODYNAS and mortality.

Females

Parameter HR [95% CI] p-value
D3_IMMUDEFANTIBODYNAS 3.692 [2.74, 4.98] < 0.001
Birth year 0.998 [0.99, 1.01] 0.678

During the follow-up period (1.1.1998 — 31.12.2019), 114 out of 759 females with D3_IMMUDEFANTIBODYNAS died.

Males

Parameter HR [95% CI] p-value
D3_IMMUDEFANTIBODYNAS 4.194 [2.91, 6.04] < 0.001
Birth year 0.987 [0.98, 1.0] 0.01

During the follow-up period (1.1.1998 — 31.12.2019), 101 out of 537 males with D3_IMMUDEFANTIBODYNAS died.

Mortality risk

Mortality risk for people of age

years, who have D3_IMMUDEFANTIBODYNAS.

N-year risk Females Males
1 0.49% 0.783%
5 2.474% 4.738%
10 6.1% 11.305%
15 11.228% 20.533%
20 18.82% 33.16%

Relationships between endpoints

Index endpoint: D3_IMMUDEFANTIBODYNAS – Other and unspecified immunodeficiencies with predominantly antibody defects

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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