Other and/or unspecified nontoxic goitre

E4_GOITRENAS

goiter: Enlargement of the thyroid gland usually caused by lack of iodine in the diet, hyperthyroidism, or thyroid nodules. Symptoms include difficulty in breathing and swallowing.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E04.8, E04.9
  • Hospital discharge: ICD-9 2419
  • Cause of death: ICD-10 E04.8, E04.9
  • Cause of death: ICD-9 2419

2 out of 7 registries used, show all original rules.

3383

4. Check minimum number of events

None

3383

5. Include endpoints

None

3383

6. Filter based on genotype QC (FinnGen only)

3267

Control definitions (FinnGen only)

Control exclude
E4_THYROID

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 22270 18757 3408
Only index persons 20487 17456 3031
Unadjusted period prevalence (%)
Whole population 0.47 0.54 0.10
Only index persons 0.56 0.64 0.12
Median age at first event (years)
Whole population 57.28 56.61 61.03
Only index persons 56.26 55.63 59.94

-FinnGen-

Key figures

All Female Male
Number of individuals 3267 2722 545
Unadjusted period prevalence (%) 0.85 0.97 0.25
Median age at first event (years) 54.88 53.42 62.15

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3383
Matched controls
33830
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
2505
FHL
Bilateral resection (also used if total removal has been performed on the other side)
175.2
307.7
198
12
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
120.1
307.7
326
30
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
5037.4
307.7
450
*
E03.89
ICD-10 Finland
Other specified hypothyroidism
113.2
307.7
271
26
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
23.1
307.7
241
112
2419X
ICD-9 Finland
Non-toxic nodular goitre, Unspecified non-toxic nodular goitre
+∞
307.7
402
*
2504
FHL
Unilateral resection or enucleation
238.7
307.7
223
10
H03BB01
ATC
carbimazole; oral
122.2
307.7
270
24
E04.8
ICD-10 Finland
Other specified nontoxic goitre
528.5
307.7
378
8
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
336.6
307.7
1125
50
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
180.0
307.7
745
53
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
1861.7
307.7
2758
80
104
Kela drug reimbursment
Thyroid insufficiency
793.8
307.7
791
13
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
248.4
307.7
274
12
T86
ICPC
Hypothyroidism/myxoedema
83.1
307.7
289
38
BAA60
NOMESCO Finland
Total thyroidectomy
1403.3
307.7
582
5
H03AA01
ATC
levothyroxine sodium; systemic
95.7
307.7
1841
417
E03
ICD-10 Finland
Other hypothyroidism
115.8
307.7
296
28
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
303.6
307.7
927
42
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
27.4
307.2
211
82
EP1AE
NOMESCO Finland
Neck ultrasound examination
6.7
265.1
459
777
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
29.8
260.1
173
61
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
695.1
201.5
197
*
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
29.1
176.4
118
42
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
11.2
167.5
180
169
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
290.1
163.2
165
6
T81
ICPC
Goitre
45.0
155.4
92
21
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
+∞
152.2
145
*
BAA20
NOMESCO Finland
Unilateral partial excision of thyroid gland
370.1
143.0
143
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.4
137.6
1682
9767
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
208.5
135.8
140
7
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
348.2
134.6
135
*
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
71.5
128.9
70
10
E04
ICD-10 Finland
Other nontoxic goitre
40.8
118.8
72
18
24199
ICD-8 Finland
Non-toxic nodular goitre, Unspecified
+∞
108.9
104
*
BAA25
NOMESCO Finland
Bilateral partial excision of thyroid gland
+∞
106.8
102
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
99.9
1089
5830
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
93.5
1461
8964
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
4.3
87.4
235
574
106
Kela drug reimbursment
Hypoparathyroidism
47.6
80.2
47
10
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
765.4
76.6
75
*
BA1AE, ,
SPAT
9.8
69.1
80
83
E83.51
ICD-10 Finland
Hypocalcemia
14.2
65.6
60
43
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
59.2
1445
9864
R13
ICD-10 Finland
Dysphagia
2.8
58.6
315
1192
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
101.8
55.0
60
6
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
70.0
54.3
62
9
ZXE00
NOMESCO Finland
One hour or less
1.7
51.6
1391
9660
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
51.6
809
4769
T72
ICPC
Benign neoplasm thyroid
19.2
48.4
38
20
R06.0
ICD-10 Finland
Dyspnoea
1.8
47.0
966
6169
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.8
46.3
247
928
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
14.2
45.9
42
30
Z2221
NOMESCO Finland
Medical doctor
1.8
44.3
986
6426
C73.92
ICD-10 Finland
Follicular carcinoma of the thyroid gland
228.0
44.0
45
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
43.7
1285
9028
A11CC03
ATC
alfacalcidol; systemic
4.5
43.5
106
239
R03AC02
ATC
salbutamol; inhalant
1.6
42.9
1891
14707
2411A
ICD-9 Finland
Non-toxic nodular goitre, Non-toxic multinodular goitre
+∞
39.7
38
*
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
381.7
38.1
38
*
N02BE01
ATC
paracetamol; systemic, rectal
2.2
37.8
3062
27597
Z71.8
ICD-10 Finland
Other specified counselling
1.7
37.8
1042
7137
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
+∞
37.6
36
*
ZXA00
NOMESCO Finland
Right side
1.7
37.4
968
6516
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
371.4
37.1
37
*
A02BC05
ATC
esomeprazole; systemic
1.6
37.0
1440
10719
EP1AE, ,
SPAT
4.5
36.7
91
208
E06.1
ICD-10 Finland
Subacute thyroiditis
+∞
36.5
35
*
N02AX02
ATC
tramadol; systemic, rectal
1.6
36.2
1449
10842
BAA50
NOMESCO Finland
Lobectomy and resection of contralateral lobe of thyroid gland
361.1
36.0
36
*
ZXA05
NOMESCO Finland
Left side
1.7
35.9
903
6022
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
35.5
1015
6993
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
35.3
969
6605
A02BC02
ATC
pantoprazole; systemic
1.6
35.2
2348
19722
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
+∞
33.4
32
*
R49.01
ICD-10 Finland
Functional dysphonia
3.0
33.0
146
494
TBA20
NOMESCO Finland
Aspiration cytology of thyroid gland
+∞
32.3
31
*
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.1
31.7
308
1514
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
31.3
467
2669
WX402
NOMESCO Finland
General anaesthesia
1.7
30.9
708
4582
R53
ICD-10 Finland
Malaise and fatigue
1.7
30.8
787
5240
C73.90
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland) without histology
85.9
30.8
34
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
30.5
770
5108
Z3226
NOMESCO Finland
Physiotherapist
1.7
30.5
642
4059
M79.6
ICD-10 Finland
Pain in limb
1.5
30.4
1446
11109
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
32.9
30.0
39
12
T85
ICPC
Hyperthyroidism/thyrotoxicosis
41.5
29.9
37
9
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.1
29.3
128
430
ZX114
NOMESCO Finland
Intramuscular
5.0
29.1
62
125
UJF32
NOMESCO Finland
Coloscopy
1.6
28.1
899
6299
2506
FHL
Thyroidectomy
283.8
27.8
28
*
C73
ICD-10 Finland
Malignant neoplasm of thyroid gland
100.9
27.7
30
*
GB1AA
NOMESCO Finland
Tracheal X-ray examination
+∞
27.1
26
*
R21
ICPC
Throat symptom/complaint
1.7
26.8
612
3943
C73.99
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland), other or unspecified histology
97.5
26.7
29
*
H02AB06
ATC
prednisolone; systemic
1.5
26.6
1548
12285
R42
ICD-10 Finland
Dizziness and giddiness
1.6
26.4
804
5557
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
26.3
919
6553
A02BC03
ATC
lansoprazole; oral
1.5
26.3
1001
7273
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
4.4
26.2
66
153
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
26.0
1447
11365
C07AB07
ATC
bisoprolol; oral
1.5
25.6
1560
12455
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
4.3
25.6
67
160
J01DB01
ATC
cefalexin; oral
1.6
25.5
2691
23994
R4110
NOMESCO Finland
Physiotherapy
1.5
25.4
935
6736
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
28.6
25.4
34
12
M25.5
ICD-10 Finland
Pain in joint
1.5
24.6
1084
8100
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
24.3
354
1999
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
24.2
928
6731
4CJ01, ,
NOMESCO Finland
+∞
24.0
23
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
23.7
761
5307
ZXA10
NOMESCO Finland
Bilateral
1.6
23.4
639
4289
R01AD09
ATC
mometasone; nasal
1.4
23.4
1466
11702
R07.0
ICD-10 Finland
Pain in throat
2.1
23.0
218
1059
J01FA10
ATC
azithromycin; systemic
1.4
22.5
1836
15338
SPAT1336
SPAT
Request for examination
2.5
22.4
138
557
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
22.4
1429
11415
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
3.4
22.1
81
245
Z3231
NOMESCO Finland
Registered nurse
1.5
22.1
853
6177
J01FA06
ATC
roxithromycin; oral
1.4
22.0
1324
10448
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
+∞
21.9
21
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
21.8
600
4029
G47.3
ICD-10 Finland
Sleep apnoea
1.6
21.7
599
4023
J01AA02
ATC
doxycycline; systemic
1.5
21.6
2609
23362
A48
ICPC
General and Unspecified, Clarification/discussion RFE/demand
2.1
21.6
200
963
R02
ICPC
Shortness of breath/dyspnoea
1.7
21.6
425
2621
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
21.4
1311
10368
M03BX02
ATC
tizanidine; oral
1.4
21.4
2007
17118
R52.9
ICD-10 Finland
Pain, unspecified
1.8
21.2
329
1893
A02BA02
ATC
ranitidine; systemic
1.6
21.2
652
4489
K30
ICD-10 Finland
Functional dyspepsia
1.7
21.1
390
2362
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
21.0
650
4482
UJD02
NOMESCO Finland
Gastroscopy
2.2
20.9
177
823
2410A
ICD-9 Finland
Non-toxic nodular goitre, Non-toxic uninodular goitre
+∞
20.9
20
*
BAA30
NOMESCO Finland
Excision of thyroid isthmus
77.3
20.7
23
*
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
211.2
20.6
21
*
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
20.4
629
4329
N03AX16
ATC
[U] pregabalin
1.5
19.9
770
5559
E06.3
ICD-10 Finland
Autoimmune thyroiditis
20.9
19.9
29
14
ZXD20
NOMESCO Finland
Day surgery
1.7
19.9
447
2852
S21
ICPC
Skin texture symptom/complaint
1.6
19.6
470
3045
M01AB05
ATC
diclofenac; systemic, rectal
1.4
19.6
2138
18576
8330/3-C73.9
ICD-O-3
Follicular carcinoma, NOS, of thyroid gland
105.7
19.6
21
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
19.4
602
4144
J02AC01
ATC
fluconazole; systemic
1.4
19.3
1414
11473
C07AA05
ATC
propranolol; systemic
1.5
19.1
625
4352
R03BA05
ATC
fluticasone; inhalant
1.6
19.0
579
3969
R03DC03
ATC
montelukast; oral
1.6
18.8
552
3750
A11CC02
ATC
dihydrotachysterol; oral
20.9
18.6
27
13
R60.0
ICD-10 Finland
Localized oedema
1.7
18.6
408
2585
N17
ICPC
Vertigo/dizziness
1.7
18.6
414
2633
G44.2
ICD-10 Finland
Tension-type headache
1.6
18.5
455
2966
A02BC01
ATC
omeprazole; systemic
1.4
18.5
883
6632
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
17.6
18.2
28
16
A04
ICPC
Weakness/tiredness general
1.6
18.2
451
2944
N06AX11
ATC
mirtazapine; oral
1.4
18.2
1066
8304
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
18.0
2217
19505
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
18.0
1526
12640
J01DA01
ATC
[U] cefalexin
1.4
17.8
1974
17055
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.7
17.8
347
2130
UJC01
NOMESCO Finland
Scopy of lower throat
4.6
17.7
42
93
JN5AQ
NOMESCO Finland
SPECT of thyroid metastasis with low-dose CT
+∞
17.7
17
*
BWD00
NOMESCO Finland
Reoperation for deep haemorrhage in endocrine surgery
+∞
17.7
17
*
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
+∞
17.7
17
*
R51.80
ICD-10 Finland
Headache
1.6
17.7
476
3167
EB1AA, ,
SPAT
1.9
17.7
223
1201
A29
ICPC
General symptom/complaint other
1.6
17.4
404
2593
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.8
17.4
282
1643
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
17.3
570
3968
M54.5
ICD-10 Finland
Low back pain
1.4
17.2
1120
8860
D06
ICPC
Abdominal pain localized other
1.8
17.2
291
1715
L17
ICPC
Foot/toe symptom/complaint
1.4
17.1
932
7153
E06.9
ICD-10 Finland
Thyroiditis, unspecified
31.6
17.0
22
7
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
17.0
439
2892
N01
ICPC
Headache
1.7
16.9
308
1855
J01FA09
ATC
clarithromycin; systemic
1.4
16.9
985
7647
WX002
NOMESCO Finland
Sedation and analgesia
1.5
16.8
636
4556
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
4.0
16.7
47
119
E05.89
ICD-10 Finland
Other thyrotoxicosis
+∞
16.7
16
*
24110
ICD-8 Finland
Non-toxic nodular goitre, Sporadic
+∞
16.7
16
*
L28
ICPC
Limited function/disability (L)
1.5
16.6
579
4074
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
16.6
693
5059
H02AB07
ATC
prednisone; oral
1.6
16.5
447
2976
R5140
NOMESCO Finland
Monitoring the use of the aid
1.7
16.5
295
1767
Z01.2
ICD-10 Finland
Dental examination
1.4
16.5
1384
11392
R49.08
ICD-10 Finland
Other specified dysphonia
2.7
16.4
87
326
R07.3
ICD-10 Finland
Other chest pain
1.7
16.4
327
2017
WZC30, ,
SPAT
2.0
16.2
185
963
S04
ICPC
Lump/swelling localized
1.7
16.0
326
2023
H04.10
ICD-10 Finland
Dry eye syndrome
1.6
16.0
394
2565
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
15.9
558
3930
R05
ICD-10 Finland
Cough
1.5
15.8
680
4986
D01
ICPC
Abdominal pain/cramps general
1.6
15.8
362
2316
R01AD08
ATC
fluticasone; nasal
1.4
15.7
886
6819
A99
ICPC
Disease/condition unspecnature/site
1.7
15.7
289
1744
S29
ICPC
Skin symptom/complaint other
1.5
15.7
612
4404
R60.9
ICD-10 Finland
Oedema, unspecified
1.9
15.6
188
997
R4130
NOMESCO Finland
Speech therapy
2.7
15.6
84
318
B01AB05
ATC
enoxaparin; parenteral
1.4
15.5
1031
8155
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.4
15.5
948
7397
M02AA07
ATC
piroxicam; topical
1.4
15.5
1189
9624
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.4
15.4
676
4971
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.7
15.4
292
1777
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
15.4
856
6571
S18
ICPC
Laceration/cut
1.3
15.3
1414
11767
R06.5
ICD-10 Finland
Mouth breathing
1.8
15.2
235
1348
N03AX12
ATC
[U] gabapentin; oral
1.5
15.2
525
3685
A60
ICPC
General and Unspecified, Result test/procedure
2.1
15.1
146
715
K59.09
ICD-10 Finland
Constipation, unspecified
1.8
15.1
211
1175
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
15.1
448
3044
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.9
15.0
200
1096
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.5
15.0
554
3940
B60
ICPC
Blood and Immunity, Result test/procedure
3.4
14.9
52
153
H53.1
ICD-10 Finland
Subjective visual disturbances
1.8
14.9
228
1306
R05
ICPC
Cough
1.4
14.8
758
5731
P01AB01
ATC
metronidazole; oral, rectal
1.3
14.7
1313
10852
BA1NN
NOMESCO Finland
I-131 dose capsel measurement
+∞
14.6
14
*
K02.1
ICD-10 Finland
Caries of dentine
1.3
14.3
1704
14663
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
14.3
992
7879
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
14.3
1410
11810
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
14.3
346
2241
WZC30
NOMESCO Finland
Teaching
1.5
14.2
473
3290
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
2.4
14.1
98
420
UKC02
NOMESCO Finland
Cystoscopy
1.6
14.0
398
2674
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.6
14.0
399
2684
D35.1
ICD-10 Finland
Benign neoplasm: Parathyroid gland
10.9
14.0
26
24
R00.2
ICD-10 Finland
Palpitations
1.7
14.0
250
1497
H02AB04
ATC
methylprednisolone; systemic
1.5
13.9
458
3178
J01FF01
ATC
clindamycin; systemic
1.4
13.8
808
6237
ZXE20
NOMESCO Finland
More than three and less than five hours
1.6
13.7
388
2604
C03CA01
ATC
furosemide; systemic
1.4
13.7
880
6899
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
13.6
448
3108
E03.8
ICD-10 Finland
Other specified hypothyroidism
+∞
13.5
13
*
A97
ICPC
No disease
1.5
13.5
529
3801
L01
ICPC
Neck symptom/complaint
1.5
13.5
491
3477
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.6
13.4
287
1801
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
13.4
1376
11557
S48
ICPC
Skin, Clarification/discussion RFE/demand
5.6
13.4
25
45
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
13.2
185
1030
SFA20
NOMESCO Finland
Two-surface restoration
1.3
13.2
1739
15109
E07.89
ICD-10 Finland
Other specified disorders of thyroid
40.2
13.1
16
*
M01AE02
ATC
naproxen; oral, rectal
1.3
13.1
1740
15124
R06AE07
ATC
cetirizine; oral
1.3
13.1
1396
11777
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
13.0
1922
16942
EB1SA, ,
SPAT
1.9
13.0
162
870
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.6
13.0
331
2170
L12
ICPC
Hand/finger symptom/complaint
1.5
12.9
488
3481
E66.8
ICD-10 Finland
Other obesity
1.9
12.9
159
851
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.8
12.9
181
1010
M01AH05
ATC
etoricoxib; oral
1.3
12.9
1954
17280
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
12.8
1546
13248
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
12.8
729
5594
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
12.8
735
5650
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
12.7
502
3610
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.5
12.6
382
2600
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.8
12.6
203
1179
R01AD12
ATC
fluticasone furoate; nasal
1.4
12.6
908
7227
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.4
12.6
724
5561
XF402
NOMESCO Finland
ECG with work load test
1.6
12.6
312
2030
J01CA04
ATC
amoxicillin; systemic
1.4
12.6
2568
23637
BAA99
NOMESCO Finland
Other operation on thyroid gland
70.1
12.6
14
*
T71
ICPC
Malignant neoplasm thyroid
+∞
12.5
12
*
8340/3-C73.9
ICD-O-3
Papillary carcinoma, follicular variant of thyroid gland
+∞
12.5
12
*
Z00.8
ICD-10 Finland
Other general examinations
1.7
12.5
224
1343
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.7
12.5
256
1591
R05FB02
ATC
cough suppressants and expectorants; systemic
1.3
12.4
1209
10049
C07AB02
ATC
metoprolol; systemic
1.4
12.4
596
4443
R03BA02
ATC
budesonide; inhalant
1.4
12.3
553
4069
A12AA04
ATC
calcium carbonate; oral
3.3
12.3
46
142
F29
ICPC
Eye symptom/complaint other
1.6
12.3
293
1889
J45.1
ICD-10 Finland
Nonallergic asthma
1.7
12.3
223
1341
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
12.3
1655
14366
R03AC03
ATC
terbutaline; inhalant
1.5
12.2
434
3053
DQE10
NOMESCO Finland
Injection of foreign material into vocal cord
9.7
12.2
24
25
L03
ICPC
Low back symptom/complaint
1.4
12.1
848
6714
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
12.1
831
6560
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.7
12.1
209
1239
M54
ICD-10 Finland
Dorsalgia
1.5
12.1
350
2361
A01
ICPC
Pain general/multiple sites
1.6
12.0
296
1923
N06AX21
ATC
duloxetine; oral
1.5
12.0
354
2396
R29
ICPC
Respiratory symptom/complaint other
1.8
12.0
197
1152
M01AH01
ATC
celecoxib; oral
1.4
12.0
586
4377
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.9
11.9
161
887
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.6
11.9
254
1593
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
11.9
767
5994
M79.1
ICD-10 Finland
Myalgia
1.5
11.8
424
2992
M79.7
ICD-10 Finland
Fibromyalgia
2.0
11.7
125
636
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.7
11.7
195
1146
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.5
11.6
341
2305
Z50.5
ICD-10 Finland
Speech therapy
3.3
11.6
43
132
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
11.5
623
4729
1930A
ICD-9 Finland
Malignant neoplasm of thyroid gland[CARCINOMA PAPILLARE THYREOIDEAE]
+∞
11.5
11
*
J31.0
ICD-10 Finland
Chronic rhinitis
1.6
11.4
242
1517
J01MA02
ATC
ciprofloxacin; systemic
1.3
11.4
1131
9400
A27
ICPC
Fear of other disease NOS
1.9
11.3
153
844
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
11.3
2167
19591
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
11.3
243
1529
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
11.2
391
2741
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
2.0
11.2
119
606
M01AG02
ATC
tolfenamic acid; oral, rectal
1.4
11.1
491
3597
H57.1
ICD-10 Finland
Ocular pain
2.0
11.1
114
573
Z01.7
ICD-10 Finland
Laboratory examination
1.5
11.0
424
3030
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.5
11.0
418
2980
K48
ICPC
Cardiovascular, Clarification/discussion RFE/demand
4.4
11.0
27
62
L08
ICPC
Shoulder symptom/complaint
1.4
11.0
663
5123
L48
ICPC
Musculoskeletal, Clarification/discussion RFE/demand
3.4
11.0
38
112
XCH00
NOMESCO Finland
Eye pressure measurement
1.8
10.9
156
875
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
2.3
10.9
78
339
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
10.9
476
3481
J01DA09
ATC
[U] cefadroxil
1.3
10.9
778
6167
L15
ICPC
Knee symptom/complaint
1.3
10.8
763
6033
Z50.1
ICD-10 Finland
Other physical therapy
1.7
10.7
176
1029
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
10.7
645
4978
WW200
NOMESCO Finland
Immunization
2.4
10.7
72
305
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.5
10.5
342
2362
L82
ICD-10 Finland
Seborrhoeic keratosis
1.4
10.5
584
4452
WZB00, ,
SPAT
1.7
10.4
191
1153
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
1.8
10.4
147
823
XF600
NOMESCO Finland
Bloodpressure measurement
1.7
10.4
169
987
BBA70
NOMESCO Finland
Implantation or transplantation of parathyroid gland
16.1
10.3
16
10
24210
ICD-8 Finland
Thyrotoxicosis with or without goitre, Toxic nodular goitre
18.8
10.3
15
8
F01
ICPC
Eye pain
2.2
10.2
87
407
C10AA05
ATC
atorvastatin; oral
1.3
10.2
1217
10316
U07
ICPC
Urine symptom/complaint other
1.6
10.2
230
1462
J37.0
ICD-10 Finland
Chronic laryngitis
2.0
10.2
101
501
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.5
10.2
356
2495
C10AA07
ATC
rosuvastatin; oral
1.3
10.2
949
7797
C08CA01
ATC
amlodipine; oral
1.3
10.1
1159
9776
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.6
10.0
208
1296
U72
ICPC
Urethritis
2.1
10.0
91
437
N05AH04
ATC
quetiapine; oral
1.4
10.0
440
3219
R69
ICD-10 Finland
Unknown and unspecified causes of morbidity
2.5
10.0
60
241
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.4
10.0
491
3663
A03
ICPC
Fever
1.4
9.9
419
3042
K85
ICPC
Elevated blood pressure
1.4
9.9
528
3991
L29
ICPC
Musculoskeletal sympt/complt other
1.6
9.9
261
1722
K43
ICPC
Cardiovascular, Other diagnostic procedure
3.0
9.8
42
141
R03BB04
ATC
tiotropium bromide; inhalant
1.5
9.8
272
1815
R74
ICPC
Upper respiratory infection acute
1.3
9.8
851
6917
K99
ICPC
Cardiovascular disease other
2.2
9.8
79
362
2409X
ICD-9 Finland
Simple and unspecified goitre, Goitre, unspecified
20.1
9.8
14
7
R20.2
ICD-10 Finland
Paraesthesia of skin
1.7
9.8
191
1172
K80
ICPC
Cardiac arrhythmia NOS
1.6
9.7
248
1624
M01AH02
ATC
rofecoxib; oral
1.4
9.7
410
2976
M01AB55
ATC
diclofenac, combinations; oral
1.6
9.7
217
1379
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.3
9.7
638
4987
E23.05
ICD-10 Finland
Lack of TSH
55.2
9.6
11
*
P06
ICPC
Sleep disturbance
1.5
9.6
303
2079
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.4
9.6
403
2923
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.0
9.6
106
548
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
9.5
348
2459
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
9.5
1115
9416
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
9.5
2884
27337
CK2S4, ,
SPAT
2.9
9.5
44
155
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
1.8
9.5
143
817
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
9.5
568
4375
M01AC06
ATC
meloxicam; systemic, rectal
1.3
9.4
1170
9948
C03AA03
ATC
hydrochlorothiazide; oral
1.5
9.4
286
1949
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
9.4
9
*
E05.4
ICD-10 Finland
Thyrotoxicosis factitia
+∞
9.4
9
*
2462A
ICD-9 Finland
Other disorders of thyroid, Cyst of thyroid
+∞
9.4
9
*
8341/3-C73.9
ICD-O-3
Papillary microcarcinoma of thyroid gland
+∞
9.4
9
*
C03DA01
ATC
spironolactone; oral
1.5
9.4
323
2257
S01
ICPC
Pain/tenderness of skin
1.8
9.3
133
749
S54
ICPC
Skin, Repair/fix-suture/cast/prosth device
2.0
9.2
101
520
SPAT1212
SPAT
Extensive examination of musculoskeletal system
1.6
9.2
229
1491
A98
ICPC
Health maint/preventive medicine
1.6
9.2
3201
30971
WX110, ,
SPAT
1.7
9.2
166
999
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.8
9.1
139
797
T90
ICPC
Diabetes non-insulin dependent
1.3
9.1
636
5011
R68.2
ICD-10 Finland
Dry mouth, unspecified
3.5
9.1
30
86
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
9.0
446
3327
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
2.5
9.0
54
217
2509
FHL
Other measure in this category
36.8
9.0
11
*
N05CF01
ATC
zopiclone; oral
1.3
9.0
968
8077
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.6
9.0
204
1301
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
9.0
1040
8756
A10BJ06
ATC
semaglutide; parenteral
1.8
8.9
127
713
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
8.9
761
6160
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
3.0
8.9
39
133
D04
ICPC
Rectal/anal pain
2.6
8.9
49
189
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
2.1
8.9
82
397
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.7
8.8
163
987
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.7
8.8
150
888
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.4
8.8
454
3411
A98
ICD-10 Finland
Other viral haemorrhagic fevers, not elsewhere classified
2.4
8.8
57
238
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.4
8.8
335
2387
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.6
8.8
224
1469
SFA10
NOMESCO Finland
One-surface restoration
1.2
8.7
1583
14014
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.7
8.7
141
823
R52.2
ICD-10 Finland
Other chronic pain
1.9
8.7
112
610
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
2.1
8.7
77
368
A11
ICPC
Chest pain NOS
1.5
8.6
238
1588
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.4
8.6
328
2336
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
1.8
8.6
126
714
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.5
8.6
280
1935
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
1.7
8.5
138
805
XA402
NOMESCO Finland
ENMG
2.1
8.5
77
370
M01AX17
ATC
nimesulide; oral
1.3
8.5
750
6092
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.4
8.5
499
3826
Z71.9
ICD-10 Finland
Counselling, unspecified
1.6
8.5
196
1255
D12
ICPC
Constipation
1.9
8.4
100
530
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.6
8.4
191
1218
D02
ICPC
Abdominal pain epigastric
1.6
8.4
184
1163
E20.8
ICD-10 Finland
Other hypoparathyroidism
90.3
8.4
9
*
J35.0
ICD-10 Finland
Chronic tonsillitis
1.8
8.4
113
624
E66.00
ICD-10 Finland
Metabolic syndrome
1.7
8.4
138
809
103
Kela drug reimbursment
Diabetes, insulin-treated
1.3
8.4
684
5500
A03FA01
ATC
metoclopramide; systemic, rectal
1.3
8.4
695
5601
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.5
8.3
310
2198
24100
ICD-8 Finland
Non-toxic nodular goitre, Endemic
+∞
8.3
8
*
U01
ICPC
Dysuria/painful urination
1.5
8.3
253
1724
T99
ICPC
Endocr/metab/nutrit disease other
2.5
8.3
48
190
L02
ICPC
Back symptom/complaint
1.5
8.3
275
1907
G43.9
ICD-10 Finland
Migraine, unspecified
1.7
8.3
148
889
Z02.7
ICD-10 Finland
Issue of medical certificate
1.6
8.3
182
1153
R03AK07
ATC
formoterol and budesonide; inhalant
1.3
8.2
586
4622
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.4
8.2
328
2356
N04BC05
ATC
pramipexole; oral
1.5
8.2
229
1531
M54.2
ICD-10 Finland
Cervicalgia
1.5
8.2
228
1523
J01DA06
ATC
[U] cefuroxime
1.4
8.2
415
3106
TQW40, ,
SPAT
1.6
8.2
209
1371
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
1.8
8.2
126
726
UJF30
NOMESCO Finland
Ileoscopy through colon
1.5
8.1
292
2057
KAD00
NOMESCO Finland
Partial nephrectomy
4.5
8.1
19
42
J45
ICD-10 Finland
Asthma
1.5
8.1
298
2109
A08
ICPC
Swelling
1.7
8.1
155
948
WX704
NOMESCO Finland
Intubation
1.5
8.1
223
1488
J01EA01
ATC
trimethoprim; systemic
1.3
8.1
881
7346
R12
ICD-10 Finland
Heartburn
1.5
8.1
230
1546
H29
ICPC
Ear symptom/complaint other
1.4
8.1
334
2416
D19
ICPC
Teeth/gum symptom/complaint
1.3
8.0
785
6456
R4110, ,
SPAT
1.5
8.0
263
1820
F45.8
ICD-10 Finland
Other somatoform disorders
1.6
8.0
174
1099
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
2.7
8.0
41
153
R04
ICPC
Breathing problem other
1.9
8.0
102
555
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.6
8.0
176
1116
U02
ICPC
Urinary frequency/urgency
1.4
7.9
457
3492
C08CA13
ATC
lercanidipine; oral
1.4
7.9
428
3238
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.4
7.9
392
2924
E66.01
ICD-10 Finland
Obesity due to excess calories
1.5
7.9
224
1504
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
7.9
1223
10610
R94.6
ICD-10 Finland
Abnormal results of thyroid function studies
6.6
7.9
19
29
R4120
NOMESCO Finland
Occupational therapy
1.6
7.9
177
1128
RD210, ,
NOMESCO Finland
2.5
7.8
47
190
C09CA01
ATC
losartan; oral
1.3
7.8
755
6200
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.6
7.8
192
1250
R61.9
ICD-10 Finland
Hyperhidrosis, unspecified
2.7
7.8
39
144
A03FA02
ATC
cisapride; oral, rectal
1.5
7.8
228
1543
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.6
7.7
187
1212
R96
ICPC
Asthma
1.4
7.7
289
2052
A02BC04
ATC
rabeprazole; oral
1.5
7.7
258
1793
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
7.7
1894
17223
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.3
7.7
687
5583
RL210, ,
NOMESCO Finland
4.3
7.7
19
44
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.3
7.7
582
4629
R49.8
ICD-10 Finland
Other and unspecified voice disturbances
2.7
7.7
39
145
M54.6
ICD-10 Finland
Pain in thoracic spine
1.5
7.7
200
1319
Z3229
NOMESCO Finland
Other healthcare associate professional
1.5
7.6
225
1525
XF404
NOMESCO Finland
Ambulatory ECG
1.5
7.6
235
1608
BA2AT
NOMESCO Finland
Biopsy of thyroid with ultrasound quidance
25.1
7.6
10
*
XKD00
NOMESCO Finland
Uroflowmetry
1.5
7.5
254
1767
XCK10
NOMESCO Finland
Photography of fundus of eye
1.5
7.5
252
1751
L13
ICPC
Hip symptom/complaint
1.3
7.5
592
4732
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
7.5
1946
17771
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.5
7.5
235
1612
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
2.3
7.5
56
250
B02AA02
ATC
tranexamic acid; systemic
1.3
7.5
464
3585
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
1.7
7.5
122
715
XKD03
NOMESCO Finland
Urethral pressure profilometry
2.0
7.5
75
376
N06AB03
ATC
fluoxetine; oral
1.4
7.5
341
2510
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.5
7.5
223
1515
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
2.0
7.4
74
370
M77.0
ICD-10 Finland
Medial epicondylitis
2.1
7.4
70
343
RK320, ,
NOMESCO Finland
3.4
7.4
26
78
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.4
7.4
301
2172
C01CA24
ATC
epinephrine; parenteral
1.6
7.3
168
1075
G50.1
ICD-10 Finland
Atypical facial pain
2.2
7.3
60
278
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.3
7.3
534
4221
A01AB09
ATC
miconazole; local oral
1.5
7.3
256
1794
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.4
7.3
336
2475
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.3
7.3
625
5049
J01FA01
ATC
erythromycin; systemic
1.4
7.3
364
2718
C739, ,
ICD-10 Finland
+∞
7.3
7
*
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.6
7.3
152
951
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
1.7
7.3
136
827
J38.3
ICD-10 Finland
Other diseases of vocal cords
2.7
7.3
36
132
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
2.8
7.3
34
121
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.4
7.3
299
2161
R01AD58
ATC
fluticasone, combinations; nasal
1.3
7.3
653
5309
A10BA02
ATC
metformin; oral
1.3
7.2
737
6086
L04
ICPC
Chest symptom/complaint
1.6
7.2
179
1168
N06AX16
ATC
venlafaxine; oral
1.4
7.2
368
2761
K29.1
ICD-10 Finland
Other acute gastritis
2.5
7.2
42
168
J39.2
ICD-10 Finland
Other diseases of pharynx
2.9
7.2
32
111
A12AA06
ATC
calcium lactate gluconate; oral
20.1
7.1
10
5
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
7.1
1285
11295
H02AB09
ATC
hydrocortisone; systemic
2.3
7.1
51
224
I50.9
ICD-10 Finland
Heart failure, unspecified
1.4
7.1
337
2496
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.5
7.1
252
1772
S22
ICPC
Nail symptom/complaint
1.6
7.1
177
1157
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
1.9
7.1
83
440
K04
ICPC
Palpitations/awareness of heart
1.6
7.1
153
967
R06AX27
ATC
desloratadine; oral
1.3
7.0
798
6669
LCA06
NOMESCO Finland
Biopsy of endometrium
1.4
7.0
406
3103
R49.09
ICD-10 Finland
Unspecified dysphonia
2.6
7.0
39
152
R49.03
ICD-10 Finland
Atrophic dysphonia
2.7
7.0
35
129
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.4
7.0
256
1810
N06AB04
ATC
citalopram; systemic
1.3
7.0
604
4882
R31
ICD-10 Finland
Unspecified haematuria
1.5
7.0
212
1445
J46
ICD-10 Finland
Status asthmaticus
1.9
7.0
85
456
E21.0
ICD-10 Finland
Primary hyperparathyroidism
2.1
7.0
61
291
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.4
7.0
317
2332
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
6.9
714
5900
F51.0
ICD-10 Finland
Nonorganic insomnia
1.3
6.9
415
3190
D25.1
ICD-10 Finland
Intramural leiomyoma of uterus
1.5
6.9
197
1326
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.5
6.9
189
1261
E20.9
ICD-10 Finland
Hypoparathyroidism, unspecified
13.8
6.9
11
8
J01MA12
ATC
levofloxacin; systemic
1.3
6.9
492
3878
SPAT1283
SPAT
Restricted health certificate
1.4
6.9
365
2753
R83
ICPC
Respiratory infection other
1.3
6.9
630
5131
TKC20
NOMESCO Finland
Catheterisation of bladder
1.6
6.9
160
1029
DFF00
NOMESCO Finland
Pure tone audiometry
1.4
6.9
281
2029
N95.0
ICD-10 Finland
Postmenopausal bleeding
1.4
6.8
323
2390
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
1.6
6.8
147
928
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
1.7
6.8
124
750
P03
ICPC
Feeling depressed
1.5
6.8
218
1503
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
1.9
6.8
81
432
C73.93
ICD-10 Finland
Anaplastic thyroid carcinoma (thyroid)
40.1
6.8
8
*
XW000
NOMESCO Finland
Bone marrow biopsy
1.8
6.8
103
593
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
1.8
6.7
100
571
L11
ICPC
Wrist symptom/complaint
1.4
6.7
247
1749
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
2.2
6.7
53
243
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
1.6
6.7
139
870
K44
ICD-10 Finland
Diaphragmatic hernia
2.8
6.7
31
110
L72.1
ICD-10 Finland
Trichilemmal cyst
1.5
6.6
171
1126
ZX120
NOMESCO Finland
Intravenous
1.4
6.6
254
1813
R25.1
ICD-10 Finland
Tremor, unspecified
1.9
6.6
82
443
H11.3
ICD-10 Finland
Conjunctival haemorrhage
1.7
6.6
121
733
GD6BD
NOMESCO Finland
Extensive CT of chest and neck
7.8
6.6
14
18
2260A
ICD-9 Finland
Benign neoplasm of thyroid gland[NEOPLASMA BENIGNUM GLANDULAE THYREOIDEAE]
7.8
6.6
14
18
D24
ICD-10 Finland
Benign neoplasm of breast
2.0
6.6
67
338
J01MA06
ATC
norfloxacin; oral
1.3
6.6
414
3203
A09
ICPC
Sweating problem
2.5
6.6
40
163
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
2.9
6.6
29
100
A06AD11
ATC
lactulose; oral
1.3
6.6
393
3019
N30.0
ICD-10 Finland
Acute cystitis
1.3
6.6
525
4200
H81
ICPC
Excessive ear wax
1.3
6.6
461
3624
L63.9
ICD-10 Finland
Alopecia areata, unspecified
3.8
6.5
19
50
TPH07
NOMESCO Finland
Cathetrisation of artery
1.4
6.5
291
2133
B01AF02
ATC
apixaban; oral
1.4
6.5
334
2506
N05BA01
ATC
diazepam; systemic, rectal
1.4
6.5
361
2743
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.5
6.5
208
1435
ZYC01
NOMESCO Finland
Remote contact by phone
1.6
6.5
148
949
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.5
6.4
210
1453
SPAT1342
SPAT
Referral to specialised care
2.6
6.4
36
141
WYA00, ,
SPAT
2.5
6.4
38
153
E03.1
ICD-10 Finland
Congenital hypothyroidism without goitre
70.0
6.4
7
*
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.4
6.4
280
2045
L05
ICPC
Flank/axilla symptom/complaint
1.6
6.4
161
1055
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.4
6.4
259
1869
WZC00, ,
SPAT
1.4
6.3
254
1827
H01
ICPC
Ear pain/earache
1.4
6.3
298
2204
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
2.0
6.3
64
323
C10AX09
ATC
ezetimibe; oral
1.3
6.3
393
3037
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.5
6.3
166
1099
D21
ICPC
Swallowing problem
2.3
6.3
45
198
ZSB00
NOMESCO Finland
Procedure related to previous procedure classified in chapter B
18.0
6.3
9
5
C73.94
ICD-10 Finland
Medullary thyroid carcinoma (thyroid)
+∞
6.3
6
*
2400A
ICD-9 Finland
Simple and unspecified goitre, Goitre, specified as simple
+∞
6.3
6
*
M14.5*E03.9
ICD-10 Finland
Arthropathy in hypothyroidism (E00-E03+)
+∞
6.3
6
*
E20
ICD-10 Finland
Hypoparathyroidism
+∞
6.3
6
*
D11
ICPC
Diarrhoea
1.4
6.2
294
2178
SFA30
NOMESCO Finland
Three-surface restoration
1.2
6.2
1198
10563
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
1.5
6.2
212
1482
H01.0
ICD-10 Finland
Blepharitis
1.5
6.2
172
1153
K29
ICPC
Cardiovascular sympt/complt other
1.7
6.2
109
655
R35
ICD-10 Finland
Polyuria
1.6
6.2
152
992
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
1.9
6.2
78
425
L09
ICPC
Arm symptom/complaint
1.6
6.2
136
865
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.4
6.1
339
2573
SXC05
NOMESCO Finland
Other oral or dental procedure
1.5
6.1
156
1025
M48.0
ICD-10 Finland
Spinal stenosis
1.3
6.1
345
2627
A03CA02
ATC
clidinium and psycholeptics; oral
1.5
6.1
170
1139
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.3
6.1
680
5662
N05CF02
ATC
zolpidem; oral
1.3
6.1
497
3985
WX320
NOMESCO Finland
Spinalanesthesy
1.2
6.1
713
5970
K59.1
ICD-10 Finland
Functional diarrhoea
1.6
6.1
148
963
A10BJ02
ATC
liraglutide; parenteral
1.9
6.1
73
391
T15
ICPC
THYROID LUMP/MASS
12.5
6.1
10
8
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.3
6.1
386
2993
C10AA01
ATC
simvastatin; oral
1.2
6.0
1182
10426
P01BA02
ATC
hydroxychloroquine; oral
1.4
6.0
256
1861
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.4
6.0
251
1819
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
3.2
6.0
23
73
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
5.2
6.0
17
33

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
643
857
9.03
307.65
3.4
1.6
4.55
4.43
pmol/l
2.08
587
747
152
19
83.72
286.98
6.3
1.4
—
—
—
0
0
187
79
25.00
263.76
5.6
1.2
139.46
393.65
u/ml
0.61
51
11
377
651
6.39
212.18
1.3
1.3
—
—
—
0
0
246
264
9.97
208.73
1.6
1.2
2.48
1.88
iu/l
0.89
63
47
2988
21398
4.39
187.18
7.2
2.6
15.32
14.48
pmol/l
56.39
2883
19150
439
1325
3.66
122.43
1.2
1.1
123.77
76.16
iu/ml
1.73
135
421
1483
8588
2.29
116.44
4.7
3.8
7.40
7.40
ph
0.32
161
1589
2109
14355
2.25
108.57
6.8
6.1
1.21
1.22
mmol/l
3.91
1923
12145
3133
26115
3.70
95.55
8.6
3.5
1.63
2.08
mu/l
3.97
3014
23663
536
2157
2.76
90.28
2.9
3.4
63.79
88.46
ng/l
14.94
491
1825
1895
12945
2.05
89.01
5.9
5.4
1.21
1.22
mmol/l
4.42
1794
11735
1385
9089
1.89
66.59
2.1
2.3
—
—
—
0
0
1677
12309
1.72
50.66
2.3
2.1
—
—
—
0
0
1649
12355
1.65
43.64
2.5
2.2
77.76
79.69
nmol/l
2.22
1526
11067
2537
21283
1.77
43.44
4.6
4.2
12.11
13.02
mm/h
2.94
2418
19578
1398
10093
1.66
42.43
3.1
3.4
2.35
2.37
mmol/l
5.76
1260
8814
2752
23724
1.86
42.08
21.8
18.0
330.17
331.00
g/l
5.49
2742
23555
1031
6924
1.70
40.91
2.1
2.3
—
—
—
0
0
1053
7169
1.68
39.39
3.8
3.7
92.83
92.53
%
0.14
1033
6980
850
5463
1.74
39.29
3.8
3.5
120.95
305.93
ng/l
3.22
600
4197
2032
16335
1.61
38.19
8.5
9.2
4.02
4.03
e9/l
0.06
1752
14189
2585
22175
1.70
36.50
7.6
7.4
77.89
78.55
u/l
0.37
2487
20761
1343
9871
1.60
36.20
4.2
3.5
93.85
118.25
e6/l
0.44
918
6742
1716
13389
1.57
35.51
2.4
2.5
—
—
—
0
0
1161
8307
1.61
34.64
3.6
3.1
97.82
66.25
e6/l
0.24
859
6217
1804
14336
1.55
33.69
5.9
5.9
0.19
0.19
e9/l
0.47
1572
12473
1751
13824
1.55
33.67
5.8
5.8
0.56
0.57
e9/l
0.63
1482
11836
1754
13861
1.55
33.52
5.8
5.8
0.04
0.04
e9/l
0.24
1484
11870
1786
14183
1.55
33.29
5.9
5.8
1.91
1.90
e9/l
0.17
1560
12449
738
4748
1.71
33.21
2.9
2.6
1.17
2.01
e6/l
0.73
376
2630
684
4335
1.72
32.42
3.0
2.7
4.53
3.61
e6/l
0.62
321
2238
974
6791
1.61
31.79
3.8
3.8
—
—
—
0
0
1024
7270
1.59
30.78
6.4
6.8
—
—
—
0
0
1072
7700
1.57
30.60
3.5
3.0
0.29
0.47
e6/l
3.20
777
5732
1979
16309
1.51
29.36
4.3
4.3
6.62
6.63
mmol/l
0.09
1897
15259
3079
28280
1.99
28.76
16.5
13.8
22.07
23.33
mg/l
1.32
2536
22207
1037
7496
1.55
28.32
3.5
2.9
—
—
—
0
0
1669
13355
1.49
28.02
6.0
6.1
28.34
27.95
%
0.78
1585
12448
1651
13184
1.49
27.99
5.9
5.8
56.83
57.28
%
0.85
1566
12266
819
5623
1.60
27.89
2.9
3.0
2.44
2.47
mmol/l
6.13
707
4952
238
1124
2.20
27.02
2.3
1.3
—
—
—
0
0
1580
12583
1.48
26.67
6.1
6.0
0.69
0.69
%
0.06
1495
11648
3154
29341
2.11
26.50
18.2
15.7
139.94
139.70
mmol/l
6.60
3126
28606
1621
12991
1.48
26.40
6.0
6.0
2.83
2.81
%
0.12
1537
12060
1628
13061
1.48
26.36
6.3
6.3
8.41
8.48
%
0.37
1542
12143
3159
29426
2.11
26.10
18.5
15.8
3.92
3.95
mmol/l
7.09
3126
28626
1612
12926
1.47
26.05
5.9
6.3
—
—
—
0
0
1560
12433
1.47
25.99
4.3
4.5
36.18
35.39
g/l
8.49
1478
11527
592
3830
1.66
25.34
1.3
1.3
—
—
—
0
0
2237
19200
1.49
25.05
5.3
4.6
6543.08
2564.12
e6/l
0.40
13
249
824
5802
1.56
24.71
2.6
2.5
6.33
6.56
e6/l
0.14
740
5160
715
4876
1.59
24.64
1.4
1.3
16.50
12.35
u/ml
0.61
254
1837
445
2684
1.76
24.60
2.6
2.3
42.55
38.94
u/l
0.17
365
2271
1464
11630
1.46
24.21
2.9
2.7
98.23
116.85
ug/l
4.77
1375
10723
610
4032
1.63
23.85
1.2
1.2
—
—
—
0
0
2272
19692
1.47
23.15
4.8
4.5
—
—
—
0
0
1456
11799
1.41
20.40
2.1
2.0
97.77
97.01
pmol/l
0.24
717
5656
1100
8509
1.43
19.89
2.1
2.1
161.88
190.98
u/l
0.79
1043
7953
718
5115
1.51
19.80
1.4
1.3
35.12
33.27
iu/ml
0.14
220
1677
1775
14933
1.40
19.71
5.5
6.1
10.86
10.93
umol/l
0.11
1722
14169
2283
20087
1.42
19.30
3.9
3.7
—
—
—
0
0
1564
12917
1.39
19.19
15.2
14.2
1.25
1.23
inr
0.40
487
3660
2974
27736
1.60
17.20
4.9
4.5
5.95
5.87
mmol/l
2.87
2775
25146
831
6285
1.43
16.42
1.9
1.7
1.05
1.15
mg/l
0.47
652
4827
3170
30145
1.82
15.96
11.5
10.4
24.14
24.36
u/l
0.32
3117
29014
619
4451
1.48
15.92
2.8
3.1
0.81
0.81
mmol/l
0.48
589
4161
2820
26125
1.48
15.48
6.0
5.5
40.14
39.47
mmol/mol
2.19
2683
24003
894
6917
1.40
15.34
2.5
2.5
3275.41
5281.58
umol/l
0.87
810
5999
539
3821
1.49
14.80
1.4
1.3
530.16
573.93
titre
0.21
126
853
469
3251
1.51
14.33
2.3
2.6
6.58
8.15
umol/l
1.28
398
2806
361
2363
1.59
14.26
2.3
2.0
376.88
377.15
nmol/l
0.01
335
2156
3249
31296
1.96
13.37
24.3
20.4
257.88
257.65
e9/l
0.07
3176
30444
1110
9046
1.34
13.32
3.0
3.2
29.81
33.46
u/l
1.60
1055
8581
3249
31309
1.95
13.15
24.3
20.4
90.83
91.22
fl
5.45
3236
30838
3249
31309
1.95
13.15
24.2
20.3
30.06
30.25
pg
8.55
3235
30835
3249
31310
1.95
13.13
24.4
20.4
6.71
6.63
e9/l
0.76
3156
30345
3246
31272
1.94
13.13
24.3
20.4
40.15
39.45
%
11.97
3097
29062
3249
31313
1.95
13.08
24.3
20.4
4.47
4.41
e12/l
10.79
3155
30354
3249
31321
1.94
12.95
24.5
20.5
133.51
132.61
g/l
3.62
3232
30850
3021
28607
1.52
12.65
5.3
4.9
2.82
2.82
mmol/l
0.13
2854
26156
1330
11192
1.31
12.52
3.7
3.6
5.76
5.87
ph
0.68
90
763
986
7964
1.34
12.38
2.6
2.9
1068.67
1297.70
ng/l
1.13
865
6835
1639
14199
1.30
12.37
4.1
3.8
0.00
0.00
estimate
1.08
199
2476
693
5307
1.38
12.25
1.5
1.4
2.20
2.40
g/l
2.38
364
3077
322
2133
1.56
12.04
5.5
7.6
—
—
—
0
0
1617
14037
1.29
11.79
5.5
5.2
0.00
0.00
estimate
0.80
197
2468
108
520
2.11
11.77
1.7
1.8
5.40
4.98
mmol/24h
0.49
99
447
117
591
2.01
11.23
1.9
1.5
296.01
302.39
mu/l
0.08
109
539
471
3420
1.44
11.23
4.1
5.1
1.03
1.03
mmol/l
0.02
433
3153
1012
8308
1.31
11.09
3.1
3.0
6.79
6.79
mmol/l
0.01
877
6927
465
3379
1.44
11.03
2.1
2.1
113.08
114.55
ug/g
0.03
383
2620
1180
9910
1.29
10.84
3.3
3.2
—
—
—
0
0
338
2323
1.51
10.65
4.7
6.1
1.24
1.31
mmol/l
0.87
333
2271
1598
13992
1.27
10.35
4.1
3.8
0.00
0.00
estimate
0.99
213
2680
347
2414
1.49
10.30
2.9
2.8
156.50
182.49
ng/l
1.09
313
2191
64
264
2.45
10.09
1.5
1.4
—
—
—
0
0
771
6182
1.32
9.82
1.3
1.2
1.20
1.55
u/ml
0.66
142
1575
962
7958
1.29
9.70
3.1
3.1
500.31
418.52
mg/l
0.18
620
4714
2608
24345
1.31
9.65
20.0
16.5
14.77
15.07
%
2.10
2579
23921
331
2313
1.48
9.60
1.1
1.2
—
—
—
0
0
1056
8860
1.28
9.48
2.8
2.5
54.90
69.03
u/l
0.91
998
8151
214
1370
1.60
9.27
5.9
8.3
24.54
24.44
mmol/l
0.21
209
1339
356
2544
1.45
9.19
1.5
1.5
—
—
—
0
0
1002
8382
1.28
9.15
3.6
3.6
6.44
8.54
mg/mmol
1.00
596
4916
248
1655
1.54
8.97
5.9
8.2
94.45
94.14
%
0.47
248
1646
2941
28017
1.38
8.93
4.6
4.3
4.75
4.81
mmol/l
2.85
2797
25786
829
6821
1.29
8.54
2.2
2.2
2.85
3.02
mg/l
1.08
703
5825
189
1204
1.60
8.38
1.3
1.3
34.32
35.90
iu/l
0.21
166
1055
146
876
1.70
8.19
3.2
3.2
—
—
—
0
0
427
3215
1.38
8.15
1.3
1.3
—
—
—
0
0
365
2688
1.40
7.96
5.8
7.0
96.32
95.80
%
1.36
353
2577
407
3078
1.37
7.55
5.6
6.6
5.19
5.11
kpa
1.11
393
2928
2911
27821
1.33
7.54
4.5
4.3
1.50
1.57
mmol/l
16.52
2743
25432
528
4155
1.32
7.50
2.4
2.4
13.41
12.76
umol/l
1.36
503
3863
164
1038
1.61
7.50
2.2
2.4
9.71
10.15
g/l
0.79
148
917
406
3077
1.36
7.42
5.6
6.6
13.00
12.48
kpa
0.97
391
2927
165
1052
1.60
7.32
2.3
2.4
2.93
2.99
g/l
0.30
151
939
1954
17882
1.22
7.25
3.0
3.0
43.79
46.12
u/l
0.48
1858
16483
278
1986
1.44
7.19
3.5
3.0
—
—
—
0
0
199
1330
1.53
7.19
2.2
2.6
0.24
0.28
e6/l
0.22
191
1284
403
3074
1.35
7.06
5.6
6.6
1.09
1.24
mmol/l
0.37
338
2445
797
9411
0.80
6.88
2.7
2.8
—
—
—
0
0
76
395
1.95
6.87
1.5
1.3
—
—
—
0
0
791
6634
1.25
6.73
1.5
1.5
21.14
21.09
nmol/l
0.03
712
5571
306
2264
1.39
6.49
2.4
2.3
6.29
6.29
ug/l
0.00
276
1947
264
1907
1.42
6.44
2.2
2.4
21.35
24.70
au/ml
0.23
23
138
80
433
1.87
6.43
1.5
1.3
0.43
0.38
nmol/l
—
7
29
207
1429
1.48
6.43
7.0
8.4
—
—
—
0
0
40
167
2.41
6.27
1.3
1.5
82.05
75.28
umol/l
0.62
40
167
2801
26780
1.27
6.18
4.1
3.9
1.31
1.26
mmol/l
4.65
2624
24268
139
893
1.58
6.03
2.3
2.3
38.50
37.62
g/l
1.04
125
778
167
1118
1.52
6.03
2.2
2.4
7.40
7.52
g/l
0.46
153
1005
167
1118
1.52
6.03
2.2
2.4
3.55
3.65
g/l
0.58
152
1005
851
7271
1.23
6.01
4.2
4.2
—
—
—
0
0
514
4151
1.28
5.95
2.3
1.9
29.34
29.53
s
0.31
501
4017
69
366
1.90
5.93
1.3
1.3
—
—
nmol/l
—
0
0
118
732
1.63
5.92
1.9
2.0
10.90
11.47
nmol/l
0.29
106
637
408
3199
1.31
5.91
1.7
1.7
—
—
—
0
0
135
867
1.58
5.88
1.2
1.2
—
—
—
0
0
131
836
1.59
5.86
2.7
2.6
—
—
—
0
0
238
1719
1.41
5.83
1.3
1.3
44.97
53.39
au/ml
—
10
98
159
1065
1.52
5.75
1.8
1.6
—
—
—
0
0
45
207
2.19
5.69
1.2
1.2
—
—
—
0
0
272
3609
0.73
5.67
4.4
4.5
33.83
33.37
%
0.32
212
2364
236
1714
1.41
5.61
1.3
1.3
99.02
196.90
u/ml
4.63
222
1577
188
1312
1.46
5.56
1.2
1.2
—
—
—
0
0
720
6097
1.23
5.48
4.6
4.3
1.01
1.02
kg/l
0.48
144
940
109
678
1.63
5.44
1.2
1.1
—
—
—
0
0
1367
12311
1.19
5.38
9.3
9.2
0.00
0.00
e9/l
0.28
1047
9973
648
5441
1.24
5.33
3.0
2.8
524.81
520.53
mosm/kgh2o
0.20
533
4614
472
3823
1.27
5.32
2.4
2.3
2.40
2.35
g/l
1.40
448
3517
68
374
1.83
5.26
1.4
1.3
65.40
45.22
mu/l
0.62
62
333
443
3575
1.28
5.14
2.5
2.4
22.02
21.96
%
0.03
384
3015
84
503
1.69
4.89
2.1
2.5
—
—
—
0
0
141
962
1.49
4.72
1.1
1.1
—
—
—
0
0
95
596
1.61
4.63
1.3
1.3
45.62
45.14
u/ml
0.01
13
79
164
1158
1.44
4.61
1.3
1.3
0.18
1.45
u/ml
2.45
20
111
362
2889
1.28
4.60
4.1
4.1
—
—
—
0
0
64
364
1.77
4.49
1.3
1.3
636.56
297.37
pmol/l
0.42
59
310
347
2764
1.28
4.48
1.2
1.4
—
—
—
0
0
127
859
1.50
4.46
2.4
2.4
—
—
—
0
0
75
449
1.69
4.40
1.3
1.2
—
—
—
0
0
407
3329
1.25
4.22
1.4
1.5
—
—
—
0
0
875
7716
1.18
4.20
1.7
1.6
1.34
1.34
mmol/l
0.02
758
6457
75
458
1.65
4.11
1.7
1.4
—
—
—
0
0
172
2322
0.73
4.04
4.7
4.1
—
—
—
0
0
827
7286
1.18
3.99
1.4
1.4
—
—
—
0
0
72
440
1.65
3.95
1.3
1.3
—
—
—
0
0
3013
29367
1.24
3.66
14.2
13.0
—
—
—
0
0
1157
10523
1.15
3.63
3.6
3.5
42.12
89.72
ng/l
0.52
751
7145
211
1635
1.31
3.41
2.5
2.4
—
—
—
0
0
12
32
3.76
3.38
1.2
1.0
0.06
0.06
u/ml
0.03
12
32
114
803
1.43
3.34
1.3
1.3
97.10
40.13
u/ml
—
6
54
62
384
1.63
3.29
1.1
1.2
17.08
16.06
u/l
0.12
49
309
22
96
2.30
3.26
1.4
1.3
144.43
74.99
nmol/24h
0.41
22
96
82
546
1.51
3.20
2.1
2.7
—
—
—
0
0
36
192
1.88
3.19
1.8
1.4
2294.64
1757.61
ml
2.21
36
187
53
318
1.68
3.18
3.2
3.1
—
—
—
0
0
7
11
6.37
3.18
1.4
4.0
23.66
23.43
mg/l
—
7
11
119
854
1.41
3.16
1.6
1.7
1.23
1.18
g/l
1.05
114
813
288
2344
1.25
3.16
3.1
3.6
2.09
2.05
mmol/l
0.07
259
2011
37
202
1.84
3.07
1.5
2.0
10.68
10.79
%
0.05
37
202
41
234
1.76
2.96
1.2
1.2
—
—
—
0
0
285
2341
1.24
2.90
3.1
3.6
6.04
5.82
kpa
3.43
277
2282
448
3848
1.19
2.88
2.1
2.0
—
—
—
0
0
266
2174
1.24
2.84
4.9
6.8
9.10
9.60
mmol/l
0.54
248
2078
119
873
1.38
2.82
1.4
1.4
310.61
281.18
ug/g
0.95
65
495
36
201
1.80
2.81
1.3
1.2
—
84.29
—
0
7
36
201
1.80
2.81
1.3
1.2
140.00
102.29
titre
—
8
35
392
3345
1.19
2.72
3.4
3.9
28.63
20.07
ug/l
0.16
311
2685
60
388
1.56
2.72
1.0
1.1
2.21
3.80
u/ml
0.92
30
178
208
1662
1.27
2.71
1.4
1.4
—
—
—
0
0
11
35
3.15
2.64
4.1
1.5
26.13
40.38
pmol/l
0.40
11
29
12
41
2.93
2.61
1.6
1.7
—
—
—
0
0
102
744
1.38
2.53
1.3
1.3
2.39
5.70
u/ml
1.82
15
136
29
157
1.85
2.52
1.1
1.7
4.86
5.25
u/l
0.54
21
128
10
31
3.23
2.51
1.0
1.2
1.98
1.59
umol/24h
—
10
31
173
1371
1.28
2.44
2.2
1.9
—
—
—
0
0
415
3599
1.17
2.40
1.6
1.7
—
—
—
0
0
249
2063
1.22
2.38
1.5
1.4
—
—
—
0
0
8
22
3.64
2.36
2.1
2.1
—
—
—
0
0
65
443
1.48
2.35
1.1
1.1
0.77
1.52
u/ml
0.92
37
215
234
1931
1.23
2.33
2.1
2.5
—
—
—
0
0
19
91
2.09
2.32
1.2
1.3
—
—
—
0
0
246
2045
1.22
2.28
1.3
1.2
—
—
—
0
0
26
142
1.84
2.23
1.1
1.0
0.46
0.88
u/ml
0.39
13
49
122
936
1.31
2.22
10.1
8.9
—
—
—
0
0
65
449
1.46
2.22
1.3
1.6
—
—
—
0
0
10
35
2.86
2.20
1.3
1.3
—
112.38
—
0
5
142
1115
1.29
2.18
2.7
3.3
920.58
4152.29
u/ml
0.67
113
944
49
731
0.67
2.15
3.6
4.6
—
—
—
0
0
115
880
1.32
2.14
1.1
1.1
—
—
—
0
0
98
735
1.34
2.10
1.3
1.3
1.52
6.82
u/ml
—
8
81
97
727
1.34
2.09
1.8
1.6
10071.45
10781.53
e6/l
0.06
65
536
40
617
0.64
2.07
3.6
3.4
20.83
26.26
mg/l
0.58
24
373
23
125
1.85
2.02
1.3
1.6
8.06
4.83
nmol/l
0.23
17
102
16
76
2.11
2.02
1.3
1.4
81.72
114.58
nmol/l
—
8
50
24
133
1.81
1.99
2.4
2.8
654.17
916.95
u/ml
1.07
24
133
51
345
1.49
1.97
1.2
1.1
—
—
—
0
0
258
2192
1.19
1.94
2.1
4.0
75.09
61.59
u/ml
0.11
252
2109
64
456
1.41
1.90
2.2
2.8
—
—
—
0
0
31
189
1.65
1.87
1.5
1.7
—
—
—
0
0
127
1010
1.27
1.81
2.1
1.8
22.18
21.40
s
0.42
114
876
25
145
1.73
1.81
2.5
1.2
159.12
290.44
u/l
0.98
25
130
54
377
1.44
1.80
1.0
1.1
1.09
1.08
u/ml
0.01
25
144
334
2926
1.16
1.75
2.4
2.5
1.79
1.82
%
0.28
299
2592
241
2057
1.18
1.75
3.3
3.2
0.85
0.78
ug/l
0.21
176
1414
24
141
1.71
1.68
2.0
1.4
—
—
—
0
0
208
1762
1.19
1.65
4.7
4.7
—
—
—
0
0
14
69
2.03
1.64
1.0
1.1
—
—
—
0
0
21
120
1.75
1.62
1.1
1.0
0.18
0.28
u/ml
—
6
29
59
429
1.38
1.60
1.2
1.1
—
18.83
—
0
20
49
345
1.43
1.59
1.2
1.1
—
—
—
0
0
35
230
1.53
1.59
1.7
2.1
4.11
7.47
umol/l
1.83
26
158
83
638
1.31
1.58
2.0
1.9
9002.03
4252.91
u/l
0.45
28
253
51
363
1.41
1.57
1.0
1.0
1.98
2.79
u/ml
0.34
21
149
48
338
1.43
1.57
1.0
1.0
0.41
1.49
u/ml
1.39
25
154
307
2698
1.15
1.56
2.1
2.1
0.22
0.21
g/l
1.13
294
2536
7
27
2.60
1.51
1.1
1.2
—
—
—
0
0
92
722
1.28
1.51
1.0
1.1
—
—
—
0
0
266
2320
1.16
1.51
3.5
3.6
—
—
—
0
0
263
2297
1.16
1.47
2.2
2.7
66.66
66.44
g/l
0.20
238
2064
182
1544
1.19
1.46
1.2
1.2
—
—
—
0
0
26
164
1.59
1.43
1.1
1.1
3.56
14.74
nmol/l
—
8
25
68
517
1.32
1.42
1.7
1.5
—
—
—
0
0
110
892
1.24
1.39
6.0
5.6
1.35
1.25
mmol/l
0.50
104
778
7
29
2.42
1.39
2.3
1.3
—
—
—
0
0
22
134
1.65
1.39
1.4
1.3
133.62
134.39
nmol/l
0.03
22
134
34
231
1.48
1.36
1.1
1.2
—
—
—
0
0
562
5174
1.10
1.34
1.7
1.7
1060.07
1190.35
nmol/l
2.77
459
3865
145
1216
1.20
1.34
1.5
1.7
1.55
1.60
g/l
0.34
132
1044
9
42
2.15
1.33
1.0
1.0
—
—
—
0
0
95
764
1.25
1.31
1.4
1.2
434.00
847.24
titre
—
5
29
22
137
1.61
1.29
1.0
1.0
0.48
0.56
u/ml
—
6
32
56
421
1.34
1.29
1.2
1.6
—
—
—
0
0
9
176
0.51
1.28
2.9
1.6
1.53
1.11
promille
—
9
134
90
722
1.25
1.28
1.7
2.0
11.81
11.79
mg/l
0.01
82
662
32
459
0.69
1.26
1.1
1.2
—
—
—
0
0
396
3595
1.11
1.25
5.4
5.2
2.13
3.27
ug/l
2.46
359
3189
6
25
2.40
1.24
1.5
1.4
—
—
—
0
0
70
549
1.28
1.21
1.9
2.2
165.48
76.34
ug/min
0.40
40
310
35
249
1.41
1.14
3.0
2.6
21.72
22.46
mg/l
0.02
26
170
47
352
1.34
1.13
2.4
1.9
89.05
1103.78
u/ml
0.67
47
346
11
58
1.90
1.12
1.2
1.3
69.88
94.53
ng/l
0.85
11
58
11
59
1.87
1.07
1.3
1.2
147.95
144.92
pmol/l
0.03
11
59
11
59
1.87
1.07
1.7
1.8
9.87
10.51
mg/l
0.10
11
48
561
6016
0.92
1.07
1.6
1.6
29691157.39
36958287.93
pmol/l
0.13
485
4957
123
1042
1.19
1.07
4.0
4.5
—
—
—
0
0
32
229
1.40
1.03
1.0
1.2
—
—
—
0
0
19
122
1.56
1.02
1.1
1.3
—
—
—
0
0
52
404
1.29
1.00
1.2
1.3
—
—
—
0
0
24
345
0.69
1.00
3.3
2.1
—
—
—
0
0
190
1679
1.14
0.98
6.6
6.7
25.35
24.77
mmol/l
1.72
185
1581
0
29
0.00
0.97
0.0
1.7
—
—
—
0
0
0
30
0.00
0.97
0.0
1.1
—
—
—
0
0
70
568
1.24
0.96
1.3
1.4
9.76
28.32
e6/l
1.22
51
426
95
796
1.20
0.95
3.4
4.1
3.77
3.83
mmol/l
0.82
95
789
223
1995
1.13
0.95
2.6
2.8
9.93
10.37
g/l
1.13
210
1820
106
898
1.19
0.95
2.3
3.3
30.92
57.15
mg/l
2.36
87
731
245
2206
1.12
0.94
2.5
2.5
73.31
70.32
e9/l
0.74
179
1645
70
570
1.23
0.93
1.5
1.4
1522.68
1390.60
e6/l
0.04
53
454
288
2620
1.11
0.92
1.5
1.5
—
—
—
0
0
34
252
1.35
0.92
1.1
1.0
0.05
0.22
u/ml
1.04
11
73
217
1944
1.12
0.91
2.5
2.8
4.51
4.91
e9/l
0.34
194
1535
14
86
1.63
0.90
1.1
1.2
—
—
—
0
0
29
211
1.38
0.88
1.5
1.2
0.32
1.04
u/ml
0.91
16
117
216
1940
1.12
0.88
2.7
2.9
4.34
4.52
kpa
0.89
210
1882
14
87
1.61
0.87
1.1
1.1
—
—
—
0
0
192
2145
0.89
0.86
4.8
4.0
0.62
0.62
%
0.01
66
702
23
322
0.71
0.86
2.5
2.4
—
—
—
0
0
36
273
1.32
0.85
1.5
1.4
18751.59
43275.43
e6/l
0.63
17
153
40
309
1.30
0.84
1.5
1.4
1873.04
2137.47
e6/l
0.17
27
223
21
297
0.71
0.83
4.9
4.2
7.36
7.14
mmol/l
0.16
16
242
51
407
1.26
0.83
1.2
1.2
—
—
—
0
0
105
902
1.17
0.82
2.4
3.3
21.65
42.36
mg/l
2.36
85
736
349
3230
1.09
0.80
1.6
1.5
—
—
—
0
0
26
351
0.74
0.79
1.6
1.6
61.69
57.91
%
0.17
13
216
24
173
1.39
0.78
3.4
3.5
—
—
—
0
0
50
402
1.25
0.78
1.1
1.2
2.25
3.77
u/ml
1.15
16
151
109
946
1.16
0.77
1.2
1.3
—
—
—
0
0
10
162
0.62
0.76
1.3
2.8
0.11
0.36
e9/l
—
10
156
216
2375
0.90
0.75
4.5
3.5
1.22
1.24
mmol/l
2.02
195
2065
78
660
1.19
0.75
1.2
1.2
—
—
—
0
0
20
142
1.41
0.72
1.1
1.0
—
—
—
0
0
32
246
1.30
0.72
1.6
1.5
—
—
—
0
0
102
888
1.15
0.70
2.5
2.2
651.88
772.08
ug/l
0.13
95
828
5
26
1.92
0.70
1.0
1.2
—
—
—
0
0
5
26
1.92
0.70
1.0
1.1
—
—
—
0
0
38
300
1.27
0.70
1.0
1.0
0.94
2.42
u/ml
1.27
17
125
18
252
0.71
0.70
1.2
1.1
—
—
—
0
0
41
328
1.25
0.69
3.7
3.2
4.15
21.99
nmol/l
0.54
41
319
7
42
1.67
0.68
1.1
1.1
0.47
1.85
u/ml
—
7
35
25
188
1.33
0.66
1.0
1.1
—
—
—
0
0
190
2084
0.91
0.65
1.3
1.3
—
—
—
0
0
32
251
1.28
0.64
1.5
1.5
—
—
—
0
0
5
29
1.73
0.64
3.8
2.7
0.40
0.86
u/field
—
5
29
27
207
1.31
0.63
2.2
2.3
—
—
—
0
0
45
546
0.82
0.63
3.0
3.7
57.73
58.26
%
0.09
45
546
39
480
0.81
0.62
1.6
1.3
—
—
—
0
0
22
164
1.34
0.62
1.2
1.5
11.14
12.94
u/l
1.30
22
155
14
96
1.46
0.61
3.1
2.2
—
—
—
0
0
8
50
1.60
0.61
1.3
1.6
—
—
—
0
0
32
253
1.27
0.61
1.3
1.1
—
—
—
0
0
20
148
1.35
0.59
2.5
3.7
—
—
—
0
0
206
2237
0.92
0.59
4.8
4.2
0.09
0.12
%
0.30
66
692
53
445
1.19
0.59
1.5
1.7
—
—
—
0
0
173
1578
1.10
0.59
2.7
3.0
128.98
126.71
g/l
0.64
167
1545
61
519
1.18
0.59
1.3
1.6
—
—
—
0
0
60
511
1.18
0.58
1.3
1.6
—
—
—
0
0
56
475
1.18
0.57
1.3
1.6
—
—
—
0
0
39
320
1.22
0.55
1.2
1.4
—
—
—
0
0
61
523
1.17
0.55
1.3
1.6
—
—
—
0
0
8
124
0.64
0.54
1.1
1.2
—
—
—
0
0
42
349
1.21
0.53
8.4
5.9
13.28
12.09
mg/l
1.14
35
322
174
1598
1.09
0.53
1.7
1.8
1.40
1.45
g/l
0.10
161
1454
196
2120
0.92
0.53
4.9
4.2
2.68
0.46
%
0.67
56
587
40
331
1.21
0.53
1.2
1.4
0.24
0.35
nmol/l
0.87
26
240
11
74
1.49
0.53
1.4
1.1
—
—
—
0
0
98
873
1.13
0.53
2.4
3.2
1.35
1.67
ratio
—
7
67
15
108
1.39
0.53
1.2
1.2
129.07
145.23
mmol/24h
0.71
15
108
42
350
1.20
0.52
1.4
1.3
—
—
—
0
0
6
100
0.60
0.51
1.5
1.1
—
—
—
0
0
42
351
1.20
0.51
1.3
1.3
34.56
35.24
u/l
0.05
37
287
173
1593
1.09
0.51
3.0
3.6
5.25
5.18
kpa
0.51
166
1515
227
2116
1.08
0.50
1.4
1.3
—
—
—
0
0
60
519
1.16
0.50
1.3
1.6
—
—
—
0
0
36
433
0.83
0.49
1.6
1.3
118.33
123.39
u/ml
—
9
90
34
280
1.22
0.48
1.0
1.1
6.50
3.69
u/ml
0.19
12
102
22
278
0.79
0.47
1.7
2.2
0.96
1.44
g/24h
—
10
127
27
218
1.24
0.46
1.1
1.1
—
—
—
0
0
41
483
0.85
0.46
1.5
1.3
—
17.20
—
0
11
863
8378
1.04
0.46
3.5
3.8
—
—
—
0
0
8
117
0.68
0.45
1.4
2.1
—
—
—
0
0
220
2347
0.93
0.44
4.7
4.2
1.05
0.86
%
0.40
79
799
710
7332
0.96
0.44
3.6
3.5
—
—
—
0
0
16
208
0.77
0.43
1.4
2.0
64.94
72.81
%
1.44
16
198
20
157
1.28
0.43
1.4
1.3
1.57
1.64
g/l
0.50
20
157
5
31
1.61
0.43
3.8
1.8
13.68
16.73
umol/l
—
5
31
5
32
1.56
0.42
2.2
3.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
16
204
0.78
0.39
1.4
2.0
18.44
16.14
%
0.35
16
198
31
367
0.84
0.39
1.8
3.0
—
—
—
0
0
168
1569
1.07
0.38
3.0
3.6
7.41
7.42
ph
0.30
17
201
19
151
1.26
0.38
1.8
1.8
0.92
2.36
u/field
1.68
13
99
5
36
1.39
0.38
1.8
1.0
—
—
—
0
0
5
36
1.39
0.38
1.8
1.0
—
—
—
0
0
5
36
1.39
0.38
1.8
1.0
—
—
—
0
0
5
36
1.39
0.38
1.4
1.4
—
—
—
0
0
24
197
1.22
0.37
1.3
1.5
0.97
0.95
g/l
0.10
24
197
5
37
1.35
0.37
1.2
1.1
—
—
—
0
0
17
134
1.27
0.36
1.1
1.1
—
—
—
0
0
59
525
1.13
0.36
2.8
3.4
—
—
—
0
0
133
1431
0.93
0.36
1.5
1.4
—
—
—
0
0
21
256
0.82
0.36
2.0
1.4
37.35
32.66
%
0.20
11
158
27
226
1.20
0.35
1.3
1.2
—
—
—
0
0
162
1518
1.07
0.35
3.1
3.6
—
—
—
0
0
35
301
1.16
0.35
1.4
1.4
—
—
—
0
0
25
297
0.84
0.33
1.5
1.4
6887.93
75814.22
e6/l
1.23
14
205
28
237
1.18
0.33
2.6
2.4
—
—
—
0
0
35
303
1.16
0.32
1.4
1.4
—
—
—
0
0
38
433
0.88
0.31
1.1
1.1
—
—
—
0
0
111
1032
1.08
0.31
1.8
1.9
2.86
1.94
ug/l
0.35
99
910
92
995
0.92
0.30
3.7
3.9
25.01
25.13
mmol/l
0.16
87
911
84
773
1.09
0.30
1.0
1.1
0.62
8.58
u/ml
—
10
76
10
75
1.33
0.30
1.0
1.2
2.15
3.19
mmol/l
—
10
67
10
75
1.33
0.30
1.4
1.7
—
—
—
0
0
8
110
0.73
0.28
11.5
11.3
739.63
852.42
nmol/l
—
8
104
66
603
1.10
0.28
2.0
2.3
122.05
126.62
g/l
0.66
49
432
8
63
1.27
0.27
3.0
2.0
—
—
—
0
0
12
150
0.80
0.27
2.5
2.9
—
—
—
0
0
10
77
1.30
0.26
1.2
1.1
—
—
—
0
0
23
267
0.86
0.25
3.3
1.3
—
—
—
0
0
40
358
1.12
0.25
1.3
1.3
—
—
—
0
0
67
617
1.09
0.25
3.2
3.0
71.35
818.89
u/ml
1.08
60
559
39
435
0.90
0.25
3.5
2.5
—
—
—
0
0
23
266
0.86
0.24
3.3
1.3
2.85
2.76
g/l
0.12
18
186
23
266
0.86
0.24
3.3
1.3
0.31
0.40
g/l
1.14
18
182
23
266
0.86
0.24
3.3
1.3
5.82
6.90
g/l
1.18
18
182
77
715
1.08
0.24
1.4
1.3
167.94
227.95
miu/ml
0.82
25
342
31
350
0.88
0.24
1.0
1.1
—
—
—
0
0
9
77
1.17
0.24
2.4
2.2
—
—
—
0
0
35
312
1.12
0.24
1.4
1.5
—
—
—
0
0
6
84
0.71
0.24
1.8
1.5
—
—
—
0
0
6
84
0.71
0.24
1.5
1.1
—
—
—
0
0
6
85
0.71
0.24
1.2
1.4
60.17
66.49
%
—
6
68
28
317
0.88
0.23
1.3
1.2
—
—
—
0
0
12
97
1.24
0.23
1.5
2.8
—
—
—
0
0
31
348
0.89
0.22
4.7
2.3
—
—
—
0
0
5
40
1.25
0.22
4.8
2.7
12.68
14.98
ml/dl
—
5
34
13
157
0.83
0.22
1.4
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
321.17
—
0
12
0
12
0.00
0.21
0.0
1.0
—
109.00
—
0
6
5
43
1.16
0.21
7.8
6.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
19
164
1.16
0.20
1.5
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
6
48
1.25
0.20
1.3
1.1
—
—
—
0
0
25
281
0.89
0.19
1.7
1.4
276.89
274.67
mosm/kgh2o
0.13
18
211
14
164
0.85
0.18
1.3
2.8
936.71
674.14
e6/l
0.55
14
155
7
59
1.19
0.18
1.0
1.2
—
—
—
0
0
26
289
0.90
0.17
2.7
2.6
—
—
—
0
0
56
523
1.07
0.17
1.3
1.4
—
—
—
0
0
5
67
0.75
0.17
2.4
1.9
—
—
—
0
0
5
67
0.75
0.17
1.0
1.0
—
—
—
0
0
17
194
0.88
0.16
1.8
2.0
2.28
2.50
ug/l
0.11
12
165
70
662
1.06
0.15
3.0
3.5
7.42
7.42
ph
0.13
60
606
37
343
1.08
0.14
1.6
1.5
35.27
31.98
g/l
0.94
32
312
155
1600
0.97
0.14
1.4
1.6
—
—
—
0
0
43
403
1.07
0.13
1.3
1.5
—
—
—
0
0
61
579
1.05
0.13
3.1
3.1
0.79
0.81
nmol/l
0.13
50
456
48
452
1.06
0.13
1.3
1.2
342.39
273.89
u/ml
0.44
28
265
51
539
0.95
0.12
2.3
2.6
15.67
16.06
%
0.27
25
274
56
532
1.05
0.11
1.4
1.3
62.49
60.82
mmol/l
0.11
43
425
16
178
0.90
0.11
1.1
1.1
—
—
—
0
0
11
126
0.87
0.11
1.1
1.2
—
—
—
0
0
751
7440
1.01
0.10
4.8
4.3
0.00
0.00
estimate
1.28
198
2441
5
45
1.11
0.09
1.0
1.1
108.98
77.83
ug/l
—
5
34
305
3002
1.02
0.09
1.6
1.6
—
—
—
0
0
11
124
0.89
0.09
1.2
2.5
—
—
—
0
0
64
665
0.96
0.09
2.2
3.3
—
—
—
0
0
27
288
0.94
0.08
1.9
1.6
—
—
—
0
0
6
57
1.05
0.08
7.5
4.4
—
—
—
0
0
20
216
0.93
0.08
1.5
2.3
37.80
40.41
%
0.34
20
211
28
263
1.07
0.08
1.6
1.5
—
—
—
0
0
29
273
1.06
0.08
1.4
1.3
—
—
—
0
0
5
65
0.77
0.08
1.2
1.2
—
—
—
0
0
7
64
1.09
0.08
1.0
1.4
35.43
21.78
%
—
7
51
7
65
1.08
0.08
1.0
1.2
—
—
—
0
0
7
67
1.04
0.08
1.1
1.5
—
—
—
0
0
7
68
1.03
0.07
1.1
1.3
10.29
21.58
%
—
7
61
6
71
0.84
0.07
1.2
1.1
—
—
—
0
0
6
71
0.84
0.07
1.2
1.1
—
—
—
0
0
6
71
0.84
0.07
1.2
1.1
—
—
—
0
0
13
143
0.91
0.07
1.2
1.3
—
—
—
0
0
11
122
0.90
0.07
1.5
1.3
—
—
—
0
0
8
92
0.87
0.06
1.4
1.9
22.13
9.51
%
—
8
86
12
131
0.92
0.05
1.8
1.5
—
—
—
0
0
10
90
1.11
0.05
1.2
1.1
1248.00
1555.19
miu/ml
—
10
90
49
475
1.03
0.05
2.4
1.9
0.77
0.80
nmol/l
0.15
42
394
25
238
1.05
0.05
2.0
2.1
2.08
2.40
u/field
0.21
12
93
92
938
0.98
0.05
2.3
3.0
0.25
0.28
g/l
0.24
35
345
52
506
1.03
0.04
2.1
3.0
30.68
33.15
umol/l
0.49
47
455
116
1142
1.02
0.04
3.2
3.6
—
—
—
0
0
22
231
0.95
0.04
1.5
1.4
6.52
6.62
mmol/l
0.05
22
220
18
170
1.06
0.04
1.2
1.1
1.07
1.04
ratio
—
5
57
29
300
0.97
0.03
1.8
1.7
—
3.20
—
0
5
18
189
0.95
0.03
1.3
1.3
2.03
2.17
mmol/l
0.24
18
176
62
610
1.02
0.02
1.4
1.6
—
—
—
0
0
21
202
1.04
0.02
1.0
1.1
—
—
—
0
0
41
419
0.98
0.02
2.8
1.6
0.93
0.74
g/l
0.57
33
310
22
228
0.96
0.02
1.3
2.0
—
—
—
0
0
11
103
1.07
0.02
1.0
1.2
—
—
—
0
0
29
298
0.97
0.02
2.7
4.3
—
—
—
0
0
15
143
1.05
0.01
1.7
2.5
47.88
41.52
%
—
8
80
55
557
0.99
0.01
3.3
3.6
3.29
2.55
mmol/l
0.87
41
395
13
124
1.05
0.00
1.9
13.5
—
—
—
0
0
13
124
1.05
0.00
1.2
2.7
—
—
—
0
0
18
186
0.97
0.00
1.1
1.0
290.44
299.47
mg/l
0.25
18
167
11
112
0.98
0.00
35.2
27.2
109.09
107.12
ug/l
0.04
11
95
12
125
0.96
0.00
1.3
1.4
—
68.00
—
0
15
29
288
1.01
0.00
1.0
1.2
—
—
—
0
0
42
422
1.00
0.00
1.1
1.1
—
—
—
0
0
16
161
0.99
0.00
1.1
1.0
—
—
—
0
0
17
171
0.99
0.00
1.8
1.6
—
—
—
0
0
28
279
1.00
0.00
1.5
1.9
—
—
—
0
0
14
144
0.97
0.00
1.4
1.5
—
—
—
0
0
14
136
1.03
0.00
1.3
3.1
7.43
7.42
ph
—
6
51
22
224
0.98
0.00
1.1
1.3
—
—
—
0
0
50
497
1.01
0.00
1.8
1.5
—
—
—
0
0
14
137
1.02
0.00
1.1
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
2.18
—
0
6
0
7
0.00
-0.00
0.0
1.4
—
0.05
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
73
0.96
-0.00
1.1
1.3
—
—
—
0
0
6
61
0.98
-0.00
1.3
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.1
—
350.13
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
83
0.96
-0.00
8.7
3.8
50.31
53.46
%
—
8
78
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
9
92
0.98
-0.00
1.3
1.9
21.89
28.83
%
—
9
86
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
9.94
—
0
5
6
59
1.02
-0.00
1.0
1.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint E4_GOITRENAS and mortality.

Females

Parameter HR [95% CI] p-value
E4_GOITRENAS 1.061 [0.97, 1.17] 0.221
Birth year 0.996 [0.99, 1.0] 0.364

During the follow-up period (1.1.1998 — 31.12.2019), 2088 out of 13454 females with E4_GOITRENAS died.

Males

Parameter HR [95% CI] p-value
E4_GOITRENAS 1.154 [1.02, 1.31] 0.028
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 606 out of 2491 males with E4_GOITRENAS died.

Mortality risk

Mortality risk for people of age

years, who have E4_GOITRENAS.

N-year risk Females Males
1 0.089% 0.195%
5 0.636% 1.32%
10 1.595% 3.405%
15 3.024% 6.447%
20 5.332% 10.87%

Relationships between endpoints

Index endpoint: E4_GOITRENAS – Other and/or unspecified nontoxic goitre

GWS hits: 19

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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