iritis: Inflammation of the iris.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
729 |
4. Check minimum number of eventsNone |
729 |
5. Include endpointsNone |
729 |
6. Filter based on genotype QC (FinnGen only) |
729 |
Control definitions (FinnGen only)
- Control exclude
- L12_DISORDSKINAPPENDIX
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF9
- Parent code in ICD-10
- L68
- Name in latin
- Hirsutismus
Similar endpoints
↥List of similar endpoints to
Hirsutism in women
based on the number of shared cases.
Similar with more cases:
- Hypertrichosis
- Disorders of skin appendages
- Polycystic ovarian syndrome, consortium definition
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4246 | 4246 | - |
| Only index persons | 4165 | 4165 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.12 | - |
| Only index persons | 0.15 | 0.15 | - |
| Median age at first event (years) | |||
| Whole population | - | 30.89 | - |
| Only index persons | - | 30.87 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 729 | 729 | - |
| Unadjusted period prevalence (%) | 0.25 | 0.25 | - |
| Median age at first event (years) | 33.03 | 33.03 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 649
- Matched controls
- 6490
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L68.0
ICD-10 Finland
Hirsutism
13141.8
323.0
624
9
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
22.0
103.7
156
92
C03DA01
ATC
spironolactone; oral
16.0
96.3
164
134
G03HB01
ATC
cyproterone and estrogen; systemic
5.2
71.7
283
838
A10BA02
ATC
metformin; oral
5.5
60.6
211
524
E66.01
ICD-10 Finland
Obesity due to excess calories
4.4
35.8
144
392
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
4.8
34.4
126
311
7041A
ICD-9 Finland
Diseases of hair and hair follicles, Hirsutism[HIRSUTISMUS]
+∞
31.5
30
*
T90
ICPC
Diabetes non-insulin dependent
4.2
30.6
127
352
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.8
30.0
142
442
G03DB01
ATC
dydrogesterone; oral
3.0
30.0
210
880
103
Kela drug reimbursment
Diabetes, insulin-treated
3.8
29.9
143
449
E66.8
ICD-10 Finland
Other obesity
5.2
29.1
97
214
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.5
27.7
352
2079
L68.9
ICD-10 Finland
Hypertrichosis, unspecified
282.1
26.9
27
*
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
9.0
26.4
57
69
A10BK03
ATC
empagliflozin; oral
7.3
24.8
61
91
G03HA01
ATC
cyproterone; systemic
124.4
22.7
24
*
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
8.1
21.2
48
63
A10BJ06
ATC
semaglutide; parenteral
10.6
20.1
39
39
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
3.0
19.7
126
479
I10
ICD-10 Finland
Essential (primary) hypertension
2.4
19.6
212
1098
E66.00
ICD-10 Finland
Metabolic syndrome
5.6
19.4
58
112
N05AH04
ATC
quetiapine; oral
2.6
18.9
164
753
T82
ICPC
Obesity
4.9
18.1
60
131
E66.9
ICD-10 Finland
Obesity, unspecified
4.8
17.3
59
133
A10BH01
ATC
sitagliptin; oral
5.1
16.8
54
114
E11
ICD-10 Finland
Type 2 diabetes mellitus
3.9
16.5
71
200
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
3.0
16.2
103
388
N05BA06
ATC
lorazepam; systemic, sublingual
6.3
15.9
42
70
L68.2
ICD-10 Finland
Localized hypertrichosis
+∞
15.7
15
*
N06AB04
ATC
citalopram; systemic
2.3
14.6
166
859
N05CF01
ATC
zopiclone; oral
2.2
14.5
175
931
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
2.8
14.3
100
398
L73.2
ICD-10 Finland
Hidradenitis suppurativa
22.9
14.3
20
9
N05AX08
ATC
risperidone; systemic
3.9
14.2
60
166
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.8
14.2
47
103
N97.0
ICD-10 Finland
Female infertility associated with anovulation
4.3
14.1
53
132
N06AX16
ATC
venlafaxine; oral
2.4
14.0
135
642
N05AX12
ATC
aripiprazole; systemic
3.9
14.0
58
158
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.4
13.7
134
644
N06AX11
ATC
mirtazapine; oral
2.0
13.5
219
1311
M79.6
ICD-10 Finland
Pain in limb
2.0
13.4
236
1464
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.3
13.3
69
226
LCA06
NOMESCO Finland
Biopsy of endometrium
2.4
13.0
125
594
R06.0
ICD-10 Finland
Dyspnoea
2.2
12.8
145
745
A10BB12
ATC
glimepiride; oral
7.7
12.8
29
39
G47.3
ICD-10 Finland
Sleep apnoea
2.5
12.5
108
487
N05BA04
ATC
oxazepam; oral
2.0
12.2
180
1034
N05AA02
ATC
levomepromazine; systemic
5.5
12.1
35
66
L70.0
ICD-10 Finland
Acne vulgaris
5.3
12.0
36
71
H03AA01
ATC
levothyroxine sodium; systemic
2.0
12.0
183
1062
N91.1
ICD-10 Finland
Secondary amenorrhoea
4.1
11.3
44
114
E66
ICD-10 Finland
Obesity
3.5
11.3
52
156
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.1
11.3
138
730
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.3
11.1
106
499
N06AB06
ATC
sertraline; oral
2.3
11.0
110
530
C07AB07
ATC
bisoprolol; oral
1.9
10.9
183
1096
N05AH03
ATC
olanzapine; systemic
3.1
10.8
59
201
SPAT1262
SPAT
Handing over of treatment supplies
2.5
10.7
89
391
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.4
10.6
95
433
A02BC02
ATC
pantoprazole; systemic
1.7
10.4
368
2793
L68.8
ICD-10 Finland
Other hypertrichosis
+∞
10.4
10
*
N03AX09
ATC
lamotrigine; oral
3.0
10.2
60
216
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.6
9.9
75
312
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.6
9.9
158
2385
P01
ICPC
Feeling anxious/nervous/tense
2.0
9.9
138
768
205
Kela drug reimbursment
Chronic hypertension
2.7
9.9
70
282
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
4.8
9.8
32
70
N03AX16
ATC
pregabalin; oral
2.0
9.7
131
719
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
9.6
272
1917
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
9.6
134
746
N06AB03
ATC
fluoxetine; oral
2.2
9.6
103
514
P76
ICPC
Depressive disorder
2.5
9.5
78
338
L17
ICPC
Foot/toe symptom/complaint
1.9
9.4
148
859
E66.0
ICD-10 Finland
Obesity due to excess calories
12.6
9.4
16
13
E28.1
ICD-10 Finland
Ovarian dysfunction: Androgen excess
+∞
9.4
9
*
A10AE04
ATC
insulin glargine; parenteral
3.0
9.4
53
184
S10
ICPC
Boil/carbuncle
3.4
9.3
44
136
TLC00
NOMESCO Finland
Insertion of intrauterine device
2.2
9.2
94
456
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
9.2
143
824
M54.4
ICD-10 Finland
Lumbago with sciatica
2.1
9.2
114
604
SPAT1240
SPAT
Therapeutic discussion
2.0
9.1
123
675
N03AG01
ATC
valproic acid; systemic, rectal
2.9
8.9
55
202
C09AA02
ATC
enalapril; systemic
2.7
8.9
61
242
N06AX12
ATC
bupropion; oral
2.4
8.8
74
327
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
8.7
116
632
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
4.6
8.6
29
66
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
9.2
8.6
17
19
A10BJ02
ATC
liraglutide; parenteral
6.5
8.5
21
33
N02AX02
ATC
tramadol; systemic, rectal
1.7
8.5
207
1383
M54.5
ICD-10 Finland
Low back pain
1.7
8.4
225
1545
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.2
8.4
91
456
L15
ICPC
Knee symptom/complaint
2.0
8.2
120
675
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.8
8.2
52
197
F29
ICD-10 Finland
Unspecified nonorganic psychosis
3.5
8.2
37
111
QBJ30
NOMESCO Finland
Correction of abdominal apron
8.3
8.1
17
21
N91.4
ICD-10 Finland
Secondary oligomenorrhoea
6.4
8.1
20
32
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
4.9
8.0
25
53
C09CA01
ATC
losartan; oral
2.2
7.9
83
408
XLA10
NOMESCO Finland
NA
2.7
7.9
54
214
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.4
7.9
66
292
A28
ICPC
Limited function/disability NOS
3.1
7.8
42
143
SPAT1310
SPAT
Counselling related to known health issue
1.7
7.8
213
1463
160
Kela drug reimbursment
exenatide
11.0
7.8
14
13
O24.1
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent
9.6
7.8
15
16
P99
ICPC
Psychological disorders other
3.6
7.8
33
94
L05.9
ICD-10 Finland
Pilonidal cyst without abscess
6.5
7.8
19
30
WX110
NOMESCO Finland
Local anesthesy
1.7
7.7
470
3982
N03AX11
ATC
topiramate; oral
3.2
7.7
39
128
N05BA01
ATC
diazepam; systemic, rectal
2.3
7.6
74
351
SPAT1216
SPAT
Assessment of functional ability
2.4
7.6
64
283
N06AA09
ATC
amitriptyline; systemic
2.5
7.6
56
232
J01FF01
ATC
clindamycin; systemic
1.7
7.5
161
1030
177
Kela drug reimbursment
Insulin glargine 300 U / ml
7.2
7.5
17
24
C07AA05
ATC
propranolol; systemic
1.8
7.4
151
951
A10BG03
ATC
pioglitazone; oral
13.6
7.4
12
9
N03AX12
ATC
gabapentin; oral
2.1
7.4
88
457
L60.0
ICD-10 Finland
Ingrowing nail
3.6
7.4
31
88
N06AX21
ATC
duloxetine; oral
2.1
7.4
81
405
S29
ICPC
Skin symptom/complaint other
2.0
7.3
93
496
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
0.6
7.3
155
2222
A02BA02
ATC
ranitidine; systemic
2.1
7.2
85
440
F61.0
ICD-10 Finland
Mixed personality disorders
4.3
7.2
25
60
A10BX04
ATC
[U] exenatide; parenteral
20.3
7.1
10
5
S18
ICPC
Laceration/cut
1.6
7.1
201
1393
A10BD07
ATC
metformin and sitagliptin; systemic
4.8
7.1
22
47
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
6.4
7.0
17
27
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
3.4
6.9
31
93
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
6.9
125
756
J02AC01
ATC
fluconazole; systemic
1.5
6.9
334
2637
SPAT1254
SPAT
Administration of medicine
2.0
6.9
90
486
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.7
6.9
45
175
N05CD07
ATC
temazepam; oral
2.7
6.9
44
168
N91.5
ICD-10 Finland
Oligomenorrhoea, unspecified
6.8
6.8
16
24
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
6.8
210
1485
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
6.8
97
542
F43.1
ICD-10 Finland
Post-traumatic stress disorder
2.9
6.8
39
139
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.5
6.8
50
206
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
6.8
109
636
M04AA01
ATC
allopurinol; systemic
3.8
6.7
27
74
H01
ICPC
Ear pain/earache
1.9
6.7
96
533
N04AA02
ATC
biperiden; systemic
6.0
6.6
17
29
H02AB09
ATC
hydrocortisone; systemic
4.7
6.6
21
46
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.9
6.6
38
135
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.7
6.6
43
166
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.1
6.6
72
361
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.6
6.6
180
1228
A10BK01
ATC
dapagliflozin; oral
4.2
6.6
23
56
L03
ICPC
Low back symptom/complaint
1.7
6.6
162
1076
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.3
6.5
57
256
L29.9
ICD-10 Finland
Pruritus, unspecified
4.1
6.4
23
57
QDH01
NOMESCO Finland
Excision of nail bed in toe
70.5
6.4
7
*
E28.0
ICD-10 Finland
Ovarian dysfunction: Estrogen excess
70.5
6.4
7
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
6.4
87
477
L28
ICPC
Limited function/disability (L)
2.2
6.4
62
296
F32
ICD-10 Finland
Depressive episode
2.3
6.4
56
253
R05FB02
ATC
cough suppressants and expectorants
1.6
6.3
192
1345
WX002
NOMESCO Finland
Sedation and analgesia
1.9
6.3
91
508
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
3.5
6.3
27
79
C10AA05
ATC
atorvastatin; oral
1.9
6.3
95
542
A10BJ01
ATC
exenatide; parenteral
26.9
6.2
8
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.3
6.2
56
259
D07AC01
ATC
betamethasone; topical
1.6
6.2
191
1342
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
6.2
171
1168
A10BH05
ATC
linagliptin; oral
5.8
6.2
16
28
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.0
6.2
83
453
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
3.4
6.1
28
86
R53
ICD-10 Finland
Malaise and fatigue
1.7
6.1
130
826
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
2.3
6.0
55
256
-50
ICPC
Medication/prescr/renewal
3.4
6.0
27
82
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
263
97
41.85
307.65
1.8
1.3
1.5
1.6
nmol/l
0.11
226
87
196
280
9.21
137.48
1.4
1.3
9.0
11.3
u/l
1.48
167
229
213
573
4.84
75.09
2.2
1.9
369.1
380.6
nmol/l
0.33
194
538
179
536
4.10
53.26
1.7
1.6
313.0
289.3
mu/l
0.68
173
472
93
214
4.84
38.34
1.6
1.4
6.0
19.8
u/l
9.62
79
180
41
41
10.54
36.56
1.2
1.5
400.1
438.2
mu/l
0.16
41
41
41
43
10.04
35.34
1.2
1.5
72.7
74.9
%
0.40
41
43
172
666
3.07
33.00
1.5
1.3
13.9
23.7
iu/l
5.35
148
568
218
1014
2.64
29.20
4.6
4.1
8.2
11.1
mg/mmol
0.42
139
647
701
5837
6.23
25.64
12.7
8.6
139.5
139.5
mmol/l
0.02
686
5660
630
4907
3.09
25.52
6.4
3.9
39.6
37.1
mmol/mol
7.44
602
4663
700
5857
5.91
24.62
12.9
8.7
3.9
3.9
mmol/l
2.70
683
5660
312
1827
2.24
24.06
2.1
1.7
99.9
98.5
pmol/l
0.17
175
1016
82
244
3.66
23.71
1.5
1.4
0.4
0.5
nmol/l
0.20
67
209
241
1281
2.32
23.33
3.8
3.3
8.1
7.9
mmol/l
0.29
209
1110
316
1927
2.13
21.34
4.9
4.3
1.2
1.2
mmol/l
0.19
287
1749
309
1891
2.10
20.45
3.7
4.0
36.2
37.0
g/l
1.89
284
1776
696
5965
4.68
19.92
6.9
4.9
1.7
1.9
mu/l
0.58
673
5684
341
2189
2.05
19.59
5.7
4.8
1.2
1.2
mmol/l
0.35
294
1809
189
972
2.27
19.27
1.8
1.5
443.6
48548629.3
pmol/l
1.82
166
861
661
5516
3.13
19.20
4.8
3.2
5.9
5.5
mmol/l
9.15
624
5188
644
5303
2.84
19.16
5.8
4.3
14.5
14.2
pmol/l
2.37
613
4977
529
4078
2.08
17.16
6.8
6.0
74.5
71.7
u/l
1.16
505
3831
139
657
2.38
17.07
1.7
1.6
1109.9
1159.4
nmol/l
0.29
111
500
415
2976
1.92
16.18
4.1
3.6
6.8
6.2
mmol/l
4.71
388
2627
183
998
2.11
15.75
1.5
1.4
21.2
21.1
nmol/l
0.01
167
880
539
4320
1.95
13.84
3.9
3.5
11.5
9.0
mm/h
4.73
503
4044
228
1399
1.92
13.82
1.8
1.7
0.6
0.8
mg/l
0.52
165
1023
350
2463
1.81
13.64
2.7
2.2
68.2
73.9
nmol/l
3.83
321
2300
239
1503
1.88
13.36
2.4
2.5
28.6
17.0
ng/l
0.35
90
596
247
1578
1.85
13.08
2.7
2.3
48.0
55.2
u/l
4.77
228
1460
251
1617
1.84
12.91
2.6
2.9
2.3
2.3
mmol/l
0.08
218
1477
663
5794
2.59
12.88
4.6
3.5
2.8
2.9
mmol/l
1.23
625
5503
355
2552
1.76
12.51
4.5
4.7
8.4
9.4
umol/l
2.40
326
2388
706
6418
4.17
12.02
10.4
7.7
27.7
23.3
u/l
7.05
691
6232
226
1446
1.82
11.68
2.1
2.0
2.7
2.6
mg/l
0.19
202
1236
655
5752
2.37
11.54
4.3
3.3
4.6
4.8
mmol/l
6.95
625
5498
653
5730
2.34
11.48
4.2
3.3
1.3
1.6
mmol/l
33.44
617
5462
121
632
2.10
11.38
2.6
2.7
0.8
0.8
mmol/l
0.45
112
596
93
446
2.24
10.83
4.5
4.6
1.0
1.0
mmol/l
0.18
87
416
628
5463
2.08
10.70
3.8
3.0
1.4
1.2
mmol/l
14.50
588
5205
285
1995
1.70
10.53
3.3
2.8
27.5
26.4
u/l
0.39
267
1902
260
1781
1.71
10.37
1.3
1.3
1.7
1.6
u/ml
0.05
66
512
104
536
2.10
10.08
3.9
3.0
30.8
32.7
%
0.90
78
403
147
857
1.90
10.04
1.7
1.6
1.4
1.3
%
0.37
130
778
251
1725
1.69
9.77
3.1
2.8
—
—
—
0
0
184
1177
1.75
9.21
2.1
2.1
1640.8
4591.6
umol/l
1.05
153
1068
23
56
4.21
8.77
1.3
1.5
365.1
454.7
pmol/l
0.28
17
39
191
1253
1.71
8.67
2.3
1.9
273.4
172.9
u/l
0.26
185
1189
120
699
1.86
8.12
1.8
2.6
329.6
493.4
ng/l
0.86
94
555
193
1301
1.66
7.81
1.7
1.6
1.6
1.3
mmol/l
3.07
171
1141
514
4356
1.61
7.74
3.5
2.6
35.8
30.6
u/l
2.15
495
4184
31
103
3.10
7.55
1.2
3.3
1.0
0.9
nmol/l
0.40
24
86
183
1241
1.63
7.16
1.3
1.3
13.7
26.7
iu/ml
2.59
42
416
30
101
3.05
7.15
1.1
1.2
1.6
4250.1
iu/ml
0.51
12
30
619
5550
1.76
6.98
10.5
7.7
95.9
94.8
ml/min/173m2
0.62
516
4438
192
1327
1.61
6.92
3.0
2.5
0.3
0.4
e6/l
0.31
153
980
674
6234
2.08
6.51
12.9
9.3
16.1
18.3
mg/l
1.28
560
4749
117
724
1.73
6.42
2.9
2.2
1.1
1.0
e6/l
0.23
74
380
43
191
2.33
6.02
2.8
2.8
5.1
5.1
kpa
0.02
38
178
42
187
2.32
5.85
1.1
1.2
—
—
—
0
0
76
1273
0.55
5.78
1.4
1.5
—
—
—
0
0
41
182
2.33
5.75
2.8
2.8
0.6
1.2
mmol/l
0.60
29
123
57
291
2.04
5.67
1.4
1.6
—
—
—
0
0
405
3381
1.45
5.57
8.7
7.5
4.4
3.9
e9/l
4.92
358
2991
41
185
2.29
5.55
1.1
1.2
—
—
—
0
0
108
684
1.68
5.42
2.9
2.4
4.6
5.2
e6/l
0.28
65
346
87
520
1.76
5.37
3.1
3.3
4.5
4.6
pmol/l
0.65
73
471
29
113
2.63
5.36
7.6
4.1
1.7
1.7
%
0.14
29
107
113
732
1.64
5.20
1.3
1.2
133.9
181.4
iu/ml
0.67
44
299
148
1028
1.55
5.08
2.1
2.3
7.9
10.3
e6/l
0.84
132
903
90
556
1.71
4.95
2.3
2.3
5.5
5.3
umol/l
0.05
69
454
60
336
1.86
4.60
7.8
6.3
1.1
0.9
mmol/l
0.16
45
254
52
278
1.94
4.58
4.3
3.6
87.5
70.3
ng/l
0.57
45
255
83
517
1.68
4.44
4.8
4.3
—
—
—
0
0
97
632
1.62
4.35
2.2
2.1
2.5
2.5
g/l
0.53
87
575
106
706
1.59
4.35
2.2
2.1
14.1
14.7
umol/l
0.31
97
643
112
758
1.56
4.29
2.6
2.2
2.4
2.4
mmol/l
2.02
94
668
8
9
8.97
4.29
1.4
1.8
—
—
—
0
0
20
74
2.75
4.11
3.1
4.0
52.6
109.6
u/ml
—
7
22
86
554
1.63
4.05
2.2
2.2
24.2
24.0
%
0.06
74
469
22
87
2.58
4.00
1.3
1.3
—
—
—
0
0
27
558
0.46
3.90
1.6
1.7
—
—
—
0
0
49
272
1.86
3.89
8.2
6.9
127.7
121.2
g/l
1.50
49
263
33
622
0.51
3.66
1.4
1.5
—
—
—
0
0
159
1194
1.42
3.64
1.3
1.3
3.5
11.8
u/ml
2.99
60
508
418
3657
1.34
3.59
3.4
2.8
75.5
57.9
ug/l
1.15
400
3460
92
622
1.55
3.54
1.7
1.7
—
—
—
0
0
8
13
6.21
3.51
2.3
2.4
—
—
—
0
0
24
494
0.47
3.45
1.4
1.5
—
—
—
0
0
73
472
1.61
3.40
1.1
1.0
—
—
—
0
0
8
14
5.76
3.34
1.3
1.7
—
—
—
0
0
63
396
1.65
3.29
1.7
1.5
—
—
—
0
0
102
724
1.48
3.13
2.9
2.5
259.9
362.5
ng/l
0.14
45
341
8
16
5.04
3.05
1.0
1.3
—
—
—
0
0
45
266
1.74
2.96
1.1
1.5
—
—
—
0
0
69
457
1.56
2.93
2.2
2.3
29.7
35.8
u/l
0.76
55
377
23
109
2.15
2.87
1.5
1.6
—
—
—
0
0
6
9
6.71
2.87
1.0
1.4
—
—
—
0
0
113
835
1.42
2.81
2.3
2.2
7470.3
5655.1
u/l
0.17
29
365
61
405
1.55
2.58
1.7
1.6
—
—
—
0
0
53
342
1.59
2.54
9.7
11.0
1.0
1.1
inr
—
8
68
69
473
1.51
2.53
1.4
1.5
—
—
—
0
0
16
70
2.31
2.42
2.0
2.4
158.4
91.5
ug/min
—
7
46
171
1385
1.31
2.36
1.9
1.8
—
—
—
0
0
48
723
0.64
2.35
1.5
1.5
—
—
—
0
0
81
583
1.44
2.34
2.0
1.7
—
—
—
0
0
28
155
1.84
2.33
1.2
1.4
423.1
392.0
mg/l
0.19
28
145
72
508
1.46
2.31
1.3
1.3
228.2
193.5
u/ml
0.09
67
475
9
28
3.24
2.31
1.9
1.8
—
—
—
0
0
233
1971
1.27
2.29
2.4
2.3
—
—
—
0
0
16
73
2.22
2.22
1.1
1.1
—
—
—
0
0
212
1783
1.27
2.17
2.3
2.1
—
—
—
0
0
53
357
1.52
2.14
3.2
2.6
1.2
1.2
mmol/l
0.66
45
296
65
458
1.46
2.12
2.5
2.6
—
—
—
0
0
72
518
1.43
2.10
1.4
1.5
—
—
—
0
0
55
375
1.50
2.10
2.6
3.5
214.7
230.1
u/l
0.70
49
356
30
176
1.73
2.09
1.7
1.5
—
—
—
0
0
16
77
2.10
1.98
1.1
1.1
—
—
—
0
0
38
242
1.60
1.97
1.4
1.4
49.0
112.6
pmol/l
0.82
38
236
15
71
2.14
1.93
1.1
1.2
—
—
—
0
0
59
418
1.45
1.89
1.3
1.2
—
23.5
—
0
15
40
264
1.55
1.80
1.6
1.8
—
—
—
0
0
32
200
1.63
1.80
1.6
2.0
8.2
4.4
ug/l
0.41
23
178
16
298
0.53
1.80
1.1
1.2
—
—
—
0
0
7
23
3.06
1.80
1.4
2.0
19.4
14.6
umol/l
—
7
23
43
289
1.52
1.79
3.5
2.8
2.3
1.8
mmol/l
0.43
38
222
47
669
0.68
1.78
1.4
1.4
—
—
—
0
0
26
154
1.71
1.78
8.9
7.6
24.4
23.8
mmol/l
0.67
26
145
47
668
0.68
1.77
1.4
1.4
—
—
—
0
0
47
667
0.68
1.76
1.4
1.4
—
—
—
0
0
47
666
0.69
1.74
1.4
1.4
—
—
—
0
0
24
141
1.73
1.70
1.2
1.3
28.3
4.6
e6/l
0.71
18
110
22
126
1.77
1.69
1.0
1.1
—
—
—
0
0
336
3032
1.20
1.68
4.3
4.0
—
—
—
0
0
46
320
1.47
1.64
2.2
3.8
29.3
23.3
ug/l
0.09
27
231
29
182
1.62
1.62
1.8
1.9
—
—
—
0
0
27
167
1.64
1.60
1.7
1.9
—
—
—
0
0
581
5536
1.24
1.59
15.4
11.3
13.6
13.4
%
1.76
574
5438
6
20
3.02
1.58
1.0
1.0
—
—
—
0
0
38
257
1.50
1.56
1.9
2.3
3.5
4.5
umol/l
0.82
27
197
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
8
33
2.44
1.54
1.1
1.1
—
—
—
0
0
6
21
2.87
1.51
3.3
1.0
—
—
—
0
0
6
21
2.87
1.51
3.3
1.0
102.7
95.8
%
—
6
21
28
178
1.60
1.51
7.2
7.8
93.9
94.6
%
0.41
28
178
24
147
1.65
1.49
1.1
1.2
—
—
—
0
0
22
132
1.69
1.47
1.2
1.2
1.3
4.5
u/ml
—
6
44
63
822
0.74
1.45
1.3
1.4
—
—
—
0
0
22
133
1.67
1.44
1.2
1.2
1.4
4.7
u/ml
—
8
44
13
67
1.96
1.39
1.3
1.8
20.9
16.8
%
—
6
28
9
42
2.16
1.34
1.0
1.1
13.7
11.0
u/l
—
9
33
31
210
1.50
1.30
1.4
2.2
—
—
—
0
0
19
114
1.68
1.29
1.4
1.3
105.0
116.7
u/ml
—
7
26
19
114
1.68
1.29
1.2
1.1
—
—
—
0
0
5
18
2.79
1.28
1.0
1.2
—
—
—
0
0
10
48
2.10
1.28
1.1
1.1
—
—
—
0
0
15
84
1.80
1.28
1.3
1.2
—
—
—
0
0
15
84
1.80
1.28
1.3
1.2
—
—
—
0
0
6
26
2.32
1.19
1.2
1.1
—
—
—
0
0
10
50
2.01
1.17
2.7
1.8
—
—
—
0
0
32
224
1.45
1.16
1.3
1.3
—
—
—
0
0
342
3160
1.15
1.16
5.4
4.3
0.0
0.0
estimate
0.50
77
667
13
72
1.82
1.15
1.1
1.1
—
—
—
0
0
30
208
1.46
1.14
1.2
1.1
—
—
—
0
0
234
2103
1.17
1.14
1.8
1.7
—
—
—
0
0
341
3154
1.15
1.13
3.8
3.1
0.0
0.0
estimate
0.50
76
643
344
3197
1.14
1.04
3.9
3.1
0.0
0.0
estimate
0.80
68
649
23
155
1.50
1.02
1.6
1.3
283.4
335.5
ug/g
0.53
15
81
21
139
1.53
1.01
1.4
1.5
8.0
6.9
mmol/l
—
10
96
12
68
1.78
1.01
1.0
1.3
—
—
—
0
0
18
115
1.58
1.00
1.1
1.3
—
—
—
0
0
50
389
1.31
0.99
1.5
1.7
4.3
3.0
mg/l
0.94
42
257
7
36
1.95
0.97
1.0
1.1
108.3
110.2
%
—
7
30
12
69
1.75
0.97
1.0
1.3
—
—
—
0
0
12
69
1.75
0.97
1.0
1.3
—
—
—
0
0
12
69
1.75
0.97
1.0
1.3
—
—
—
0
0
12
69
1.75
0.97
1.0
1.3
—
—
—
0
0
22
149
1.49
0.96
2.0
2.2
—
—
—
0
0
0
32
0.00
0.95
0.0
1.1
—
—
—
0
0
12
70
1.73
0.93
1.0
1.3
—
—
—
0
0
20
134
1.51
0.92
3.4
2.7
25.7
25.1
mmol/l
0.39
20
129
55
441
1.27
0.89
1.6
1.5
—
—
—
0
0
37
281
1.33
0.88
1.6
1.6
—
—
—
0
0
25
178
1.42
0.87
1.7
2.3
3.6
3.6
g/l
0.07
25
168
11
64
1.73
0.86
1.1
1.1
—
—
—
0
0
24
172
1.41
0.82
1.4
1.2
—
—
—
0
0
234
2153
1.13
0.79
1.6
1.5
—
—
—
0
0
20
140
1.44
0.77
1.1
1.3
210.2
238.2
u/ml
—
10
97
6
34
1.77
0.76
1.3
2.7
—
—
—
0
0
10
59
1.70
0.76
2.1
1.4
—
—
—
0
0
119
1051
1.16
0.74
1.9
1.7
—
—
—
0
0
6
108
0.55
0.73
1.2
1.3
—
—
—
0
0
6
109
0.55
0.72
1.2
1.3
—
—
—
0
0
7
40
1.76
0.71
1.9
1.5
—
—
—
0
0
7
41
1.71
0.70
1.0
1.1
1530.3
1488.6
miu/ml
—
7
41
5
29
1.73
0.64
1.4
1.4
—
—
—
0
0
5
29
1.73
0.64
3.2
2.4
24.8
52.8
umol/l
—
5
24
5
30
1.67
0.61
1.0
1.3
—
—
—
0
0
182
1677
1.11
0.60
4.2
3.4
0.0
0.0
estimate
1.08
74
664
12
174
0.68
0.59
1.8
1.7
7.9
7.4
mmol/l
—
7
104
266
2505
1.10
0.57
3.9
3.1
—
—
—
0
0
8
54
1.49
0.57
1.4
2.3
—
—
—
0
0
626
6143
1.13
0.56
14.1
9.9
39.9
39.5
%
0.69
480
5132
13
90
1.45
0.55
1.0
1.2
—
—
—
0
0
9
60
1.51
0.54
1.0
1.2
—
—
—
0
0
14
100
1.41
0.52
1.1
1.5
—
—
—
0
0
14
100
1.41
0.52
1.1
1.5
3.9
3.8
g/l
—
6
83
14
100
1.41
0.52
1.1
1.5
8.1
7.5
g/l
—
8
88
6
40
1.50
0.51
1.5
1.6
—
—
—
0
0
147
1354
1.11
0.50
2.0
1.9
—
—
—
0
0
16
119
1.35
0.48
3.7
3.6
4.2
4.2
e9/l
0.07
16
119
13
93
1.41
0.48
1.8
1.5
—
—
—
0
0
18
137
1.32
0.47
1.1
1.1
—
—
—
0
0
30
245
1.23
0.47
1.7
2.2
42.9
39.7
u/l
0.24
24
228
33
273
1.22
0.47
1.2
1.4
—
—
—
0
0
7
49
1.43
0.46
1.0
1.2
—
—
—
0
0
5
31
1.62
0.43
1.0
1.0
—
—
—
0
0
16
122
1.32
0.42
3.7
3.8
61.2
56.8
%
1.02
16
122
8
59
1.36
0.41
1.6
3.4
35.5
21.1
mg/l
—
8
46
8
59
1.36
0.41
1.6
3.4
38.7
30.5
mg/l
—
8
48
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
5
35
1.43
0.39
6.4
1.6
—
—
—
0
0
21
169
1.25
0.39
1.1
1.3
3.4
13.5
u/ml
—
5
39
9
71
1.27
0.36
2.1
2.4
—
—
—
0
0
30
349
0.85
0.33
2.3
2.1
—
—
—
0
0
76
830
0.91
0.33
1.4
1.5
—
—
—
0
0
7
52
1.35
0.31
1.1
1.3
—
—
—
0
0
10
75
1.34
0.30
1.3
1.1
—
—
—
0
0
7
56
1.25
0.29
1.3
1.3
—
—
—
0
0
7
57
1.23
0.29
1.3
1.3
—
—
—
0
0
10
129
0.77
0.28
1.1
1.3
—
—
—
0
0
9
119
0.75
0.27
1.2
1.2
—
—
—
0
0
49
445
1.11
0.25
1.2
1.4
234.9
246.3
miu/ml
0.08
27
237
571
5640
1.06
0.23
4.1
4.0
—
—
—
0
0
12
147
0.81
0.23
1.4
1.5
—
—
—
0
0
18
153
1.18
0.22
1.2
1.0
5.3
2.2
u/ml
—
9
81
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
16
138
1.16
0.17
2.5
2.2
0.6
0.7
%
0.30
16
131
139
1340
1.05
0.16
4.1
3.2
1.0
1.0
kg/l
0.48
26
201
8
72
1.11
0.16
1.3
1.3
—
—
—
0
0
5
44
1.14
0.10
1.0
1.4
—
—
—
0
0
5
45
1.11
0.10
1.0
1.0
—
—
—
0
0
11
97
1.14
0.09
1.2
1.6
3.0
3.2
g/l
—
6
84
37
390
0.95
0.09
2.7
2.2
113.5
83.0
ml/min/173m2
0.40
16
127
6
57
1.05
0.08
6.3
3.6
23.8
68.0
u/ml
—
6
57
5
62
0.81
0.08
1.8
1.4
—
—
—
0
0
5
64
0.78
0.08
1.0
1.4
—
—
—
0
0
5
65
0.77
0.08
1.2
1.2
—
—
—
0
0
24
225
1.07
0.07
1.0
1.1
8.2
1.7
u/ml
0.54
12
80
22
235
0.93
0.07
1.7
2.2
2.7
5.5
iu/l
—
8
103
7
82
0.85
0.07
1.1
1.9
—
—
—
0
0
9
85
1.06
0.07
1.2
1.1
—
—
—
0
0
10
97
1.03
0.00
1.7
3.9
—
153.1
—
0
10
5
52
0.96
0.00
1.0
1.4
—
—
—
0
0
6
61
0.98
0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
5.0
—
0
5
6
60
1.00
0.00
1.3
1.2
—
—
—
0
0
6
61
0.98
0.00
1.3
1.2
—
—
—
0
0
6
61
0.98
0.00
1.3
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
7
70
1.00
0.00
1.3
1.8
—
—
—
0
0
8
84
0.95
0.00
1.3
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
0.00
1.6
1.7
1.1
0.9
g/l
—
5
51
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
68.4
—
0
5
0
8
0.00
0.00
0.0
1.6
—
1.2
—
0
8
6
60
1.00
0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_HIRSUTISM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_HIRSUTISM | 1.3 [1.05, 1.61] | 0.015 |
| Birth year | 0.998 [0.99, 1.01] | 0.583 |
During the follow-up period (1.1.1998 — 31.12.2019), 95 out of 3551 females with L12_HIRSUTISM died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have L12_HIRSUTISM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.129% | No data |
| 5 | 0.784% | No data |
| 10 | 2.05% | No data |
| 15 | 4.113% | No data |
| 20 | 7.223% | No data |
Relationships between endpoints
↥Index endpoint: L12_HIRSUTISM – Hirsutism in women
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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