Other articular cartilage disorders

M13_CARTILAGE

cartilage disease: Softening and degeneration of the CARTILAGE. Pathological processes involving the chondral tissue (CARTILAGE).

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M24.1
  • Hospital discharge: ICD-9 7180
  • Hospital discharge: ICD-8 7249
  • Cause of death: ICD-10 M24.1
  • Cause of death: ICD-9 7180
  • Cause of death: ICD-8 7249

2 out of 7 registries used, show all original rules.

941

4. Check minimum number of events

None

941

5. Include endpoints

None

941

6. Filter based on genotype QC (FinnGen only)

920

Control definitions (FinnGen only)

Control exclude
M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M24
Name in latin
Alia vitia cartilaginum articularium

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7026 3215 3754
Only index persons 6071 2847 3224
Unadjusted period prevalence (%)
Whole population 0.10 0.09 0.10
Only index persons 0.11 0.10 0.12
Median age at first event (years)
Whole population 37.19 39.65 34.93
Only index persons 35.55 37.92 33.46

-FinnGen-

Key figures

All Female Male
Number of individuals 920 450 470
Unadjusted period prevalence (%) 0.19 0.16 0.22
Median age at first event (years) 35.17 34.26 36.05

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
941
Matched controls
9410
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M17.1
ICD-10 Finland
Other primary gonarthrosis
30.8
307.7
330
162
M24.1
ICD-10 Finland
Other articular cartilage disorders
+∞
307.7
295
*
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
24.6
299.4
227
120
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
57.8
279.0
159
33
1220
FHL
Arthroscopy
43.9
274.3
167
46
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
72.7
251.6
137
22
72498
ICD-8 Finland
Internal derangement of joint, Alio loco definito
+∞
229.9
211
*
72499
ICD-8 Finland
Internal derangement of joint, Derangement of other joints
+∞
224.2
206
*
M19.0
ICD-10 Finland
Primary arthrosis of other joints
22.6
194.2
148
77
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
40.3
189.6
117
33
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
+∞
182.4
169
*
7180F
ICD-9 Finland
Other derangement of joint, Articular cartilage disorder[NIVELRUSTON SAIRAUS,POLVI]
+∞
182.4
169
*
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
16.7
181.8
162
116
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
14.6
172.3
166
136
M16.1
ICD-10 Finland
Other primary coxarthrosis
25.3
161.2
116
52
M01AX05
ATC
glucosamine; oral
6.7
131.7
250
479
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
73.2
125.3
68
10
M09AX01
ATC
hyaluronic acid; parenteral
22.3
123.7
93
46
1221
FHL
Arthroscopy and meniscus surgery
49.0
109.4
64
14
1223
FHL
Arthroscopy and articular cartilage surgery
1141.0
106.5
102
*
M25.5
ICD-10 Finland
Pain in joint
4.5
102.0
352
1106
L90
ICPC
Osteoarthrosis of knee
14.6
100.3
93
70
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
138.1
94.0
99
8
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
992.3
93.5
90
*
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
47.7
91.8
54
12
M20.1
ICD-10 Finland
Hallux valgus (acquired)
16.6
86.3
74
48
M13.9
ICD-10 Finland
Arthritis, unspecified
13.5
83.9
81
65
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
6.7
82.1
142
242
1225
FHL
Arthroscopy and other therapeutic procedure
43.0
81.3
49
12
72410
ICD-8 Finland
Internal derangement of joint, Other shoulder derangement
+∞
80.4
76
*
N02AX02
ATC
tramadol; systemic, rectal
3.5
79.8
513
2380
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
36.9
78.1
49
14
L15
ICPC
Knee symptom/complaint
4.1
74.8
255
774
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
35.3
74.0
47
14
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
15.4
73.1
65
45
WX320
NOMESCO Finland
Spinalanesthesy
4.0
71.1
249
768
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
18.0
68.3
56
33
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
8.3
67.3
93
123
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
14.8
67.0
61
44
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
3.2
66.5
490
2396
M23.8
ICD-10 Finland
Other internal derangements of knee
21.5
64.9
49
24
M22.4
ICD-10 Finland
Chondromalacia patellae
123.9
64.8
69
6
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
91.6
61.8
68
8
M01AH01
ATC
celecoxib; oral
3.8
57.3
212
671
M01AH05
ATC
etoricoxib; oral
3.0
56.4
633
3789
M75.1
ICD-10 Finland
Rotator cuff syndrome
3.2
55.8
294
1162
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
9.0
55.2
70
83
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
6.0
54.0
101
184
L04AX03
ATC
methotrexate; systemic
7.4
52.9
80
117
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
+∞
50.5
48
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
6.2
50.4
91
160
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
5.1
49.9
112
241
7177A
ICD-9 Finland
Internal derangement of knee, Chondromalacia of patella
+∞
49.4
47
*
B01AB05
ATC
enoxaparin; parenteral
2.9
46.8
316
1415
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
5.1
45.7
103
222
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
+∞
45.2
43
*
ZXA00
NOMESCO Finland
Right side
2.9
45.1
278
1183
N03AX12
ATC
[U] gabapentin; oral
3.4
45.0
192
660
B01AF01
ATC
rivaroxaban; oral
4.1
44.2
134
365
ZXA05
NOMESCO Finland
Left side
2.9
43.7
265
1115
N03AX16
ATC
[U] pregabalin
3.0
43.4
254
1048
M79.6
ICD-10 Finland
Pain in limb
2.6
43.4
411
2167
P01BA02
ATC
hydroxychloroquine; oral
7.7
42.0
60
82
N02AJ06
ATC
codeine and paracetamol; systemic
2.5
39.9
415
2263
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
67.4
39.4
45
7
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.7
38.8
137
414
84400
ICD-8 Finland
Sprains and strains of knee and leg
12.3
38.7
39
33
S83.2
ICD-10 Finland
Tear of meniscus, current
5.1
38.1
85
181
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
192.3
36.0
37
*
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
12.5
35.2
35
29
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
+∞
34.6
33
*
M10.9
ICD-10 Finland
Gout, unspecified
5.9
34.0
63
113
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
10.7
33.5
37
36
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.2
33.2
149
522
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
+∞
32.5
31
*
7170A
ICD-9 Finland
Internal derangement of knee, Old bucket handle tear of medial meniscus
+∞
30.4
29
*
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
12.4
30.0
30
25
L13
ICPC
Hip symptom/complaint
2.9
29.9
159
612
WX111
NOMESCO Finland
Local infiltration anesthesia
110.3
29.8
32
*
M01AC06
ATC
meloxicam; systemic, rectal
2.3
29.4
342
1902
N02BE01
ATC
paracetamol; systemic, rectal
3.3
29.3
847
6868
L08
ICPC
Shoulder symptom/complaint
2.5
29.0
218
1000
N06AA09
ATC
amitriptyline; systemic
3.4
28.3
110
352
ACC51
NOMESCO Finland
Release of median nerve
3.9
28.2
87
238
S18
ICPC
Laceration/cut
2.1
27.6
428
2651
M02AA07
ATC
piroxicam; topical
2.2
27.3
343
1956
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
4.2
27.3
76
193
M01AB05
ATC
diclofenac; systemic, rectal
2.2
27.3
632
4550
M17.5
ICD-10 Finland
Other secondary gonarthrosis
77.5
26.9
30
*
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
7.5
26.9
39
54
NFF25
NOMESCO Finland
Cleaning of hip joint, arthroscopic
278.7
26.9
27
*
X59
ICD-10 Finland
Exposure to unspecified factor
2.6
26.8
191
852
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
6.0
26.5
48
84
M03BX02
ATC
tizanidine; oral
2.1
26.2
604
4309
1222
FHL
Arthroscopy and synovial surgery
+∞
26.2
25
*
H02AB06
ATC
prednisolone; systemic
2.1
25.6
436
2776
L89
ICPC
Osteoarthrosis of hip
10.7
25.4
28
27
9254
FHL
Arthrotomy (includes biopsy, revision, loose removal, fixation, and similar procedures)
51.5
25.4
30
6
M19.9
ICD-10 Finland
Arthrosis, unspecified
6.7
25.3
41
64
B01AX06
ATC
[U] rivaroxaban
59.7
25.1
29
5
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
256.6
24.8
25
*
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
133.6
24.7
26
*
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
133.6
24.7
26
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.7
24.6
153
637
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
3.7
24.4
80
228
A07EC01
ATC
sulfasalazine; oral, rectal
5.0
24.4
53
110
L01BA01
ATC
methotrexate; systemic
30.1
24.2
32
11
M70.6
ICD-10 Finland
Trochanteric bursitis
3.0
24.1
119
438
Z3226
NOMESCO Finland
Physiotherapist
2.5
24.1
175
785
NGU20
NOMESCO Finland
Removal of internal fixation device from knee or lower leg
9.3
23.9
29
32
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
4.1
23.9
67
171
M01AX17
ATC
nimesulide; oral
2.3
23.8
232
1185
N02AA05
ATC
oxycodone; systemic
2.5
23.4
176
802
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.7
23.3
77
221
M54.5
ICD-10 Finland
Low back pain
2.1
23.2
327
1925
X58
ICD-10 Finland
Exposure to other specified factors
2.7
23.1
145
605
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.7
22.1
73
209
R03AC02
ATC
salbutamol; inhalant
2.0
22.1
508
3531
N06AX21
ATC
duloxetine; oral
2.8
22.0
117
448
L17
ICPC
Foot/toe symptom/complaint
2.2
22.0
249
1346
M19.2
ICD-10 Finland
Other secondary arthrosis
117.8
21.7
23
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.1
21.7
97
337
A02BC02
ATC
pantoprazole; systemic
2.0
21.5
622
4656
M01AB08
ATC
etodolac; oral
3.4
21.4
83
264
M01AE02
ATC
naproxen; oral, rectal
1.9
21.4
508
3556
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
4.3
21.3
57
140
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
20.9
241
1308
M01AE03
ATC
ketoprofen; systemic, rectal
2.0
20.9
346
2142
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
4.1
20.8
58
147
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.3
20.8
84
274
M48.0
ICD-10 Finland
Spinal stenosis
2.8
20.8
112
431
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
20.8
328
1996
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.1
20.8
91
312
NHG26
NOMESCO Finland
Fusion between bones of ankle or ankle and foot
112.5
20.6
22
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
20.6
359
2258
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
3.7
20.3
66
187
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.4
20.2
76
237
J01AA02
ATC
doxycycline; systemic
2.1
20.2
741
5961
SPAT1153
SPAT
Removal of sutures
2.0
20.1
282
1644
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
5.8
20.0
37
66
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
20.0
328
2018
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
19.9
280
1633
A02BC05
ATC
esomeprazole; systemic
1.9
19.7
373
2403
9243
FHL
Plastic of the patella and its tendons
32.0
19.3
25
8
M25.2
ICD-10 Finland
Flail joint
56.2
19.0
22
*
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
+∞
18.8
18
*
71301
ICD-8 Finland
Osteo-arthritis and allied conditions, Arthritis (arthrosis) genus
+∞
18.8
18
*
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
+∞
18.8
18
*
L40.5
ICD-10 Finland
Arthropathic psoriasis
71.4
18.8
21
*
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
71.4
18.8
21
*
NBB20
NOMESCO Finland
Primary total prosthetic replacement of humero-scapular joint
30.7
18.4
24
8
NG2AA
NOMESCO Finland
Patella X-ray examination
30.7
18.4
24
8
WX200
NOMESCO Finland
Interscalenous plexus blockade
6.8
18.4
29
44
RF210, ,
NOMESCO Finland
6.8
18.4
29
44
NF1AA
NOMESCO Finland
Hip X-ray examination
3.7
18.3
60
171
M15
ICD-10 Finland
Polyarthrosis
4.7
18.1
42
92
M54.4
ICD-10 Finland
Lumbago with sciatica
2.2
18.1
167
825
N02BF01
ATC
gabapentin; oral
3.0
17.8
85
306
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
6.3
17.7
30
49
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
3.8
17.5
55
152
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
29.4
17.5
23
8
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
17.5
107
439
L88
ICPC
Rheumatoid/seropositive arthritis
16.3
17.1
27
17
M01AE11
ATC
tiaprofenic acid; oral, rectal
4.4
17.0
43
101
L04AA13
ATC
[U] leflunomide
51.0
17.0
20
*
NG1DA
NOMESCO Finland
X-ray of knees
51.0
17.0
20
*
L29
ICPC
Musculoskeletal sympt/complt other
3.0
17.0
81
291
A02BC01
ATC
omeprazole; systemic
2.0
16.9
243
1415
J01DB01
ATC
cefalexin; oral
2.0
16.8
750
6206
M16
ICD-10 Finland
Coxarthrosis [arthrosis of hip]
5.2
16.8
35
70
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
5.0
16.7
36
74
9271
FHL
Hallux surgery
+∞
16.7
16
*
NGF40
NOMESCO Finland
Repair of defect of cartilage in the knee joint with transplant
+∞
16.7
16
*
7180A
ICD-9 Finland
Other derangement of joint, Articular cartilage disorder[NIVELRUSTON SAIRAUS,OLKANIVEL]
+∞
16.7
16
*
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
+∞
16.7
16
*
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
91.7
16.6
18
*
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
91.7
16.6
18
*
SPAT1202
SPAT
Intra-articular injection
6.4
16.4
27
43
M02AA10
ATC
ketoprofen; topical
2.2
16.1
147
721
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
21.4
16.0
23
11
R4110
NOMESCO Finland
Physiotherapy
1.9
16.0
249
1487
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.5
15.9
104
440
M24.4
ICD-10 Finland
Recurrent dislocation and subluxation of joint
61.1
15.8
18
*
NBG10
NOMESCO Finland
Acromioplastia
6.0
15.8
28
48
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.5
15.7
56
169
72490, ,
ICD-8 Finland
+∞
15.7
15
*
NGC20
NOMESCO Finland
Secondary implantation of prosthesis in knee joint, normal prosthesis
+∞
15.7
15
*
R4120
NOMESCO Finland
Occupational therapy
3.1
15.6
66
221
72908
ICD-8 Finland
Other diseases of joint, Alii definiti
26.8
15.6
21
8
M04AA01
ATC
allopurinol; systemic
2.5
15.6
104
444
NGT60
NOMESCO Finland
Forcible manipulation of knee joint
162.6
15.5
16
*
G56.2
ICD-10 Finland
Lesion of ulnar nerve
4.0
15.4
45
118
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.4
15.4
57
176
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
15.3
632
5015
S83.5
ICD-10 Finland
Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
4.3
15.2
40
97
M79.1
ICD-10 Finland
Myalgia
2.3
15.2
130
621
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
15.0
168
891
NGE35
NOMESCO Finland
Plastic repair of ligament of knee not using prosthetic material, anterior cruciate, arthroscopic
5.5
15.0
29
54
L16
ICPC
Ankle symptom/complaint
2.5
15.0
97
408
Z50.1
ICD-10 Finland
Other physical therapy
3.5
15.0
53
159
1224
FHL
Arthroscopy and loose removal
57.6
14.8
17
*
M20.2
ICD-10 Finland
Hallux rigidus
18.7
14.7
22
12
M01AH02
ATC
rofecoxib; oral
2.5
14.6
101
438
M25.0
ICD-10 Finland
Haemarthrosis
+∞
14.6
14
*
212
Kela drug reimbursment
Gout
+∞
14.6
14
*
M93.2
ICD-10 Finland
Osteochondritis dissecans
81.4
14.6
16
*
NGF20
NOMESCO Finland
Operation for osteochondritis of knee, open
81.4
14.6
16
*
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
4.8
14.6
33
71
J01DA01
ATC
[U] cefalexin
1.7
14.5
556
4287
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
152.3
14.5
15
*
L28
ICPC
Limited function/disability (L)
2.2
14.4
136
675
M24.2
ICD-10 Finland
Disorder of ligament
27.7
14.3
19
7
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
10.7
14.3
27
26
N02BF02
ATC
pregabalin; oral
3.2
14.2
57
185
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
3.4
14.0
51
156
WZA00
NOMESCO Finland
Concise certificate
3.3
13.9
53
167
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
17.9
13.9
21
12
S43.0
ICD-10 Finland
Dislocation of shoulder joint
3.8
13.9
43
118
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
2.6
13.8
85
349
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
3.3
13.7
52
163
M03BC01
ATC
orphenadrine (citrate); systemic
1.9
13.6
199
1156
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
15.0
13.6
22
15
G47.3
ICD-10 Finland
Sleep apnoea
1.9
13.6
210
1243
M10.0
ICD-10 Finland
Idiopathic gout
5.5
13.6
26
48
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
3.5
13.6
48
144
7350A
ICD-9 Finland
Acquired deformities of toe, Hallux valgus (acquired)
+∞
13.6
13
*
M23.4
ICD-10 Finland
Loose body in knee
+∞
13.6
13
*
NHG82
NOMESCO Finland
Fusion of other tarsal joint
+∞
13.6
13
*
9241
FHL
Due to repeated dislocation of the shoulder joint plastic
+∞
13.6
13
*
NGC60
NOMESCO Finland
Exchange or addition of patellar part
+∞
13.6
13
*
7174A
ICD-9 Finland
Internal derangement of knee, Derangement of lateral meniscus
+∞
13.6
13
*
H02AB04
ATC
methylprednisolone; systemic
2.2
13.5
128
636
R03DC03
ATC
montelukast; oral
2.1
13.5
149
785
D07AC01
ATC
betamethasone; topical
1.7
13.5
318
2137
TQW40
NOMESCO Finland
Remowal of suture of skin
2.8
13.4
67
247
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
13.3
164
898
E8859
ICD-8 Finland
Fall on same level from slipping, stumbling or tripping
3.5
13.3
46
136
R06AE07
ATC
cetirizine; oral
1.7
13.2
366
2568
M19.8
ICD-10 Finland
Other specified arthrosis
4.5
13.2
32
73
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
15.3
13.1
21
14
NHF25
NOMESCO Finland
Operation for debridement of ankle joint, arthroscopic
17.0
13.0
20
12
L20
ICPC
Joint symptom/complaint NOS
4.4
12.9
32
74
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.5
12.9
31
70
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
11.8
12.8
23
20
NBL22
NOMESCO Finland
Myotomy, tenotomy or excision of tendon of upper arm
6.1
12.6
22
37
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
70.8
12.6
14
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
12.6
160
885
NHG70
NOMESCO Finland
Arthroplasty of first tarsometatarsal joint
+∞
12.5
12
*
M22.0
ICD-10 Finland
Recurrent dislocation of patella
+∞
12.5
12
*
M22.1
ICD-10 Finland
Recurrent subluxation of patella
+∞
12.5
12
*
NGK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of knee or lower leg
131.7
12.5
13
*
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
131.7
12.5
13
*
M07.3
ICD-10 Finland
Other psoriatic arthropathies
131.7
12.5
13
*
WX002
NOMESCO Finland
Sedation and analgesia
2.0
12.4
153
837
S80.0
ICD-10 Finland
Contusion of knee
2.7
12.4
66
252
M01AB55
ATC
diclofenac, combinations; oral
3.0
12.4
55
190
R01BA52
ATC
pseudoephedrine, combinations; oral
1.7
12.3
275
1811
NBF25
NOMESCO Finland
Operation for humeroscapular osteochondritis, arthroscopic
4.8
12.2
27
57
M35.7
ICD-10 Finland
Hypermobility syndrome
16.1
12.2
19
12
L12
ICPC
Hand/finger symptom/complaint
2.1
12.0
130
678
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
13.6
12.0
20
15
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
4.5
12.0
29
66
J01FA06
ATC
roxithromycin; oral
1.7
11.9
348
2459
M77.1
ICD-10 Finland
Lateral epicondylitis
2.5
11.9
75
312
ZXD20
NOMESCO Finland
Day surgery
2.2
11.8
108
528
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
10.7
11.8
22
21
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
10.7
11.8
22
21
M01AE01
ATC
ibuprofen; systemic, rectal
2.0
11.8
816
7207
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
5.6
11.7
22
40
L04AB01
ATC
etanercept; parenteral
30.4
11.7
15
5
TNG10
NOMESCO Finland
Puncture of knee
65.8
11.6
13
*
WZA90
NOMESCO Finland
Other medical or dental certificate
1.8
11.5
186
1111
7152F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, secondary[OSTEORTHROSIS SECUNDARIA,POLVI]
+∞
11.5
11
*
NGC30
NOMESCO Finland
Secondary implantation of prosthesis in knee joint, special prosthesis
+∞
11.5
11
*
NGE10
NOMESCO Finland
Incision or suture of capsule of knee joint
+∞
11.5
11
*
R06.0
ICD-10 Finland
Dyspnoea
1.8
11.4
217
1361
A02BA02
ATC
ranitidine; systemic
1.9
11.4
173
1013
NFB40
NOMESCO Finland
Primary total prosthetic replacement of hip joint using hybrid technique
12.0
11.4
20
17
NFC20
NOMESCO Finland
Secondary implantation of hip prosthesis
35.5
11.3
14
*
M23.3
ICD-10 Finland
Other meniscus derangements
35.5
11.3
14
*
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
9.8
11.3
22
23
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
11.3
317
2211
J01FA10
ATC
azithromycin; systemic
1.6
11.2
490
3804
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.6
11.1
65
260
R01AD09
ATC
mometasone; nasal
1.6
11.1
377
2754
RD211, ,
NOMESCO Finland
3.0
11.0
48
164
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
11.0
189
1150
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
11.0
118
614
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
10.9
545
4354
A02BC03
ATC
lansoprazole; oral
1.7
10.9
248
1633
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
5.5
10.9
21
39
NH1AD
NOMESCO Finland
Ankle and foot CT
5.2
10.8
22
43
J04AB02
ATC
rifampicin; systemic
10.7
10.8
20
19
NF1DA
NOMESCO Finland
X-ray of hips
18.1
10.7
16
9
R05
ICD-10 Finland
Cough
1.8
10.7
174
1039
9255
FHL
Joint auger removal
28.4
10.7
14
5
M03BC51
ATC
orphenadrine, combinations; systemic
1.7
10.7
231
1500
72221
ICD-8 Finland
Osteochondrosis, Dissecans
60.7
10.6
12
*
M77.4
ICD-10 Finland
Metatarsalgia
2.9
10.6
49
173
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
10.6
185
1130
M54.3
ICD-10 Finland
Sciatica
2.7
10.6
57
219
M79.7
ICD-10 Finland
Fibromyalgia
4.1
10.5
29
73
9273
FHL
Other surgery for toe deformity or pain condition, e.g., Morton, hammer toe
111.2
10.4
11
*
7180G
ICD-9 Finland
Other derangement of joint, Articular cartilage disorder[NIVELRUSTON SAIRAUS,NILKKA]
+∞
10.4
10
*
NGC00
NOMESCO Finland
Exchange of a loose part of prosthesis in knee joint
+∞
10.4
10
*
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
+∞
10.4
10
*
NGC99
NOMESCO Finland
Other secondary prosthetic replacement inknee joint, other or unspecified
+∞
10.4
10
*
73799
ICD-8 Finland
Hallux valgus and varus
+∞
10.4
10
*
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
5.5
10.4
20
37
Z3231
NOMESCO Finland
Registered nurse
1.7
10.4
234
1534
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.9
10.4
50
181
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
5.2
10.3
21
41
H02AB07
ATC
prednisone; oral
2.1
10.3
106
542
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.6
10.3
60
240
R03AC03
ATC
terbutaline; inhalant
2.0
10.3
117
621
NG1AA, ,
SPAT
2.6
10.2
60
241
XA402
NOMESCO Finland
ENMG
4.2
10.2
27
66
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
5.4
10.1
20
38
R01AD01
ATC
beclometasone; nasal
1.9
10.1
141
802
ZXE00
NOMESCO Finland
One hour or less
1.6
10.1
311
2208
M01AH03
ATC
valdecoxib; oral
2.7
10.1
56
219
S93.4
ICD-10 Finland
Sprain and strain of ankle
2.2
10.0
87
416
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
10.0
382
2850
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
10.0
614
5102
L03
ICPC
Low back symptom/complaint
1.7
10.0
206
1319
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.3
9.9
76
345
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
9.9
372
2762
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
3.0
9.9
44
152
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.1
9.9
98
494
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
5.2
9.9
20
39
NB2AT
NOMESCO Finland
Intra artrial injection of shoulder with ultrasound guidance
20.3
9.8
14
7
R20.2
ICD-10 Finland
Paraesthesia of skin
2.5
9.8
62
258
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.8
9.8
50
187
AA1AD
NOMESCO Finland
CT of head and brain
1.7
9.6
236
1579
Z71.8
ICD-10 Finland
Other specified counselling
1.6
9.6
244
1649
A01
ICPC
Pain general/multiple sites
2.3
9.6
73
331
S83.0
ICD-10 Finland
Dislocation of patella
10.2
9.5
18
18
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
9.5
441
3425
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
3.1
9.5
39
129
M17.2
ICD-10 Finland
Post-traumatic gonarthrosis, bilateral
101.0
9.4
10
*
ZX140
NOMESCO Finland
Intra articular
101.0
9.4
10
*
M01CB01
ATC
sodium aurothiomalate; parenteral
101.0
9.4
10
*
T93.3
ICD-10 Finland
Sequelae of dislocation, sprain and strain of lower limb
17.7
9.4
14
8
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
30.3
9.4
12
*
7188E
ICD-9 Finland
Other derangement of joint, Other joint derangement, not elsewhere classified[MB ARTICULI, LIGAM ET CARTILAG AL DEF,LONKKANIVEL]
+∞
9.4
9
*
NGB10
NOMESCO Finland
Primary partial prosthetic replacement of knee joint, demi prosthesis
+∞
9.4
9
*
7183A
ICD-9 Finland
Other derangement of joint, Recurrent dislocation of joint[LUXATIO HABITUALIS, OLKANIVEL]
+∞
9.4
9
*
72904
ICD-8 Finland
Other diseases of joint, Dislocatio spontanea
+∞
9.4
9
*
M01AC01
ATC
piroxicam; systemic, rectal
2.0
9.3
111
598
M01AB16
ATC
aceclofenac; oral
3.7
9.3
29
80
J01FF01
ATC
clindamycin; systemic
1.7
9.3
223
1484
N04BC05
ATC
pramipexole; oral
2.3
9.2
71
323
E883A
ICD-9 Finland
Fall into hole or other opening in surface
2.7
9.2
49
187
S70.0
ICD-10 Finland
Contusion of hip
3.2
9.1
35
111
H02BX01
ATC
methylprednisolone, combinations; systemic
2.9
9.1
43
154
M18.1
ICD-10 Finland
Other primary arthrosis of first carpometacarpal joint
11.6
9.1
16
14
M24.8
ICD-10 Finland
Other specific joint derangements, not elsewhere classified
37.1
9.0
11
*
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
9.0
165
1019
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
9.0
119
665
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
8.9
144
856
NG1AD
NOMESCO Finland
Knee CT examination
8.1
8.9
19
24
N02AC04
ATC
dextropropoxyphene; oral
3.2
8.9
35
113
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
6.9
8.9
21
31
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
4.5
8.9
21
47
S83.4
ICD-10 Finland
Sprain and strain involving (fibular)(tibial) collateral ligament of knee
3.8
8.8
26
69
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
3.3
8.8
32
98
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.4
8.8
31
93
S83.3
ICD-10 Finland
Tear of articular cartilage of knee, current
10.8
8.8
16
15
M54.2
ICD-10 Finland
Cervicalgia
2.3
8.8
67
304
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.0
8.7
96
503
G44.2
ICD-10 Finland
Tension-type headache
1.9
8.7
108
590
M01AB01
ATC
indometacin; systemic, rectal
2.3
8.7
67
305
UJF32
NOMESCO Finland
Coloscopy
1.6
8.7
212
1413
M96.0
ICD-10 Finland
Pseudarthrosis after fusion or arthrodesis
50.5
8.7
10
*
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
50.5
8.7
10
*
NCF25
NOMESCO Finland
Operation for osteochondritis of elbow joint, arthroscopic
50.5
8.7
10
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
8.7
181
1158
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
8.6
170
1070
WZC30
NOMESCO Finland
Teaching
1.8
8.6
142
850
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
8.6
232
1585
S89.9
ICD-10 Finland
Unspecified injury of lower leg
3.6
8.6
28
80
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
3.2
8.6
33
105
9244
FHL
Plastic or reconstruction of ligaments of the knee other than the lumbar region
16.5
8.6
13
8
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
3.5
8.5
29
85
R5110, ,
SPAT
2.6
8.5
49
195
N06AX16
ATC
venlafaxine; oral
1.9
8.5
117
662
S40.0
ICD-10 Finland
Contusion of shoulder and upper arm
2.7
8.5
44
166
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
8.4
202
1340
L01
ICPC
Neck symptom/complaint
1.9
8.4
116
657
M01AE51
ATC
ibuprofen, combinations; systemic
4.9
8.4
18
37
M77.0
ICD-10 Finland
Medial epicondylitis
3.8
8.4
25
67
NHG20
NOMESCO Finland
Fusion of talocrural joint
+∞
8.3
8
*
RF410, ,
NOMESCO Finland
10.9
8.3
15
14
R50.9
ICD-10 Finland
Fever, unspecified
1.8
8.3
122
705
R52.2
ICD-10 Finland
Other chronic pain
3.3
8.3
31
97
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.2
8.3
67
312
Z01.2
ICD-10 Finland
Dental examination
1.5
8.2
349
2636
B01AB04
ATC
dalteparin; parenteral
2.8
8.2
40
146
J01CA04
ATC
amoxicillin; systemic
1.6
8.2
701
6119
M15.8
ICD-10 Finland
Other polyarthrosis
7.6
8.2
18
24
SPAT1212
SPAT
Extensive examination of musculoskeletal system
2.3
8.2
62
281
QDB10, ,
SPAT
4.6
8.1
19
42
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.1
8.1
81
410
RF420, ,
NOMESCO Finland
9.0
8.1
16
18
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.7
8.0
43
165
Z3229
NOMESCO Finland
Other healthcare associate professional
2.2
8.0
69
329
84500
ICD-8 Finland
Sprains and strains of ankle and foot, Ankle
4.2
8.0
21
51
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
8.0
198
1322
R03BA05
ATC
fluticasone; inhalant
1.7
8.0
147
908
R42
ICD-10 Finland
Dizziness and giddiness
1.7
8.0
177
1150
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
7.9
230
1596
9057A
ICD-9 Finland
Late effects of musculoskeletal and connective tissue injuries, Late effect of sprain and strain without mention of tendon injury
13.2
7.9
13
10
R96
ICPC
Asthma
2.1
7.9
75
373
SFA10
NOMESCO Finland
One-surface restoration
1.5
7.8
448
3586
M65.3
ICD-10 Finland
Trigger finger
2.7
7.8
41
156
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
2.7
7.8
41
156
L14
ICPC
Leg/thigh symptom/complaint
2.3
7.8
61
280
N06AX11
ATC
mirtazapine; oral
1.5
7.8
276
2003
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
3.9
7.7
22
57
J01FA09
ATC
clarithromycin; systemic
1.5
7.7
259
1855
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
15.2
7.7
12
8
S43.4
ICD-10 Finland
Sprain and strain of shoulder joint
2.8
7.7
37
134
9056A
ICD-9 Finland
Late effects of musculoskeletal and connective tissue injuries, Late effect of dislocation
45.4
7.7
9
*
ZXA10
NOMESCO Finland
Bilateral
1.7
7.7
144
892
M47.9
ICD-10 Finland
Spondylosis, unspecified
3.5
7.7
26
76
SFA20
NOMESCO Finland
Two-surface restoration
1.5
7.6
486
3964
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
18.5
7.6
11
6
8449X
ICD-9 Finland
Sprains and strains of knee and leg, Unspecified site of knee and leg
18.5
7.6
11
6
TQW40, ,
SPAT
2.3
7.6
59
270
R03AK07
ATC
formoterol and budesonide; inhalant
1.6
7.6
178
1171
A29
ICPC
General symptom/complaint other
1.9
7.6
101
565
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.1
7.6
76
385
R52.9
ICD-10 Finland
Pain, unspecified
2.1
7.5
75
379
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.6
7.5
24
68
NGE15
NOMESCO Finland
Incision fo capsule of knee joint, arthroscopic
80.7
7.4
8
*
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
80.7
7.4
8
*
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
3.4
7.4
26
78
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
7.4
88
474
NB1AD
NOMESCO Finland
Shoulder CT examination
6.0
7.4
19
32
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
6.0
7.4
19
32
S66.3
ICD-10 Finland
Injury of extensor muscle and tendon of other finger at wrist and hand level
3.8
7.4
22
59
M54.6
ICD-10 Finland
Pain in thoracic spine
2.2
7.4
60
280
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.6
7.4
204
1397
R51.80
ICD-10 Finland
Headache
1.8
7.4
114
669
SPAT1229
SPAT
Assessment of need for aid
2.3
7.3
53
235
R01AD12
ATC
fluticasone furoate; nasal
1.5
7.3
246
1761
M16.3
ICD-10 Finland
Other dysplastic coxarthrosis
+∞
7.3
7
*
NGF30
NOMESCO Finland
Fixation of loose body of joint of knee
+∞
7.3
7
*
7180E
ICD-9 Finland
Other derangement of joint, Articular cartilage disorder[NIVELRUSTON SAIRAUS,LONKKANIVEL]
+∞
7.3
7
*
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.4
7.3
25
74
R5599
NOMESCO Finland
Other rehabilitation service
3.4
7.3
25
74
UKC02
NOMESCO Finland
Cystoscopy
1.7
7.3
129
787
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
2.9
7.3
33
116
J01MA02
ATC
ciprofloxacin; systemic
1.5
7.2
320
2424
R05
ICPC
Cough
1.6
7.2
184
1235
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
7.2
235
1671
M01AX01
ATC
nabumetone; oral
2.9
7.2
33
117
NDG76
NOMESCO Finland
Fusion of DIP joint
30.3
7.2
9
*
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.9
7.2
89
487
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.0
7.1
30
101
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
7.1
100
569
M25.4
ICD-10 Finland
Effusion of joint
8.9
7.1
14
16
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.9
7.1
94
526
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.1
7.1
28
91
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
10.1
7.0
13
13
L10
ICPC
Elbow symptom/complaint
2.5
7.0
43
177
9242
FHL
Other reconstruction or plastic surgery of shoulder joint (including ac joint)
7.1
7.0
16
23
L04AB04
ATC
adalimumab; parenteral
7.1
7.0
16
23
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
7.0
101
581
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
6.9
113
673
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
4.0
6.9
19
48
C07AB07
ATC
bisoprolol; oral
1.4
6.9
407
3254
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
6.8
206
1436
M75.3
ICD-10 Finland
Calcific tendinitis of shoulder
4.2
6.8
18
44
N02AJ13
ATC
tramadol and paracetamol; systemic
3.8
6.8
20
53
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.3
6.8
53
243
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.9
6.8
90
503
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
5.7
6.8
18
32
WX290
NOMESCO Finland
Other blockage of nerve
1.4
6.8
367
2884
NHL14
NOMESCO Finland
Shortening or lengthening of achilles tendon
40.3
6.8
8
*
M23.5
ICD-10 Finland
Chronic instability of knee
40.3
6.8
8
*
NBB10
NOMESCO Finland
Primary partial prosthetic replacement of humero-scapular joint not using cement, other or unspecified
40.3
6.8
8
*
S15
ICPC
Foreign body in skin
2.3
6.8
49
218
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
3.2
6.8
26
83
L04AB06
ATC
golimumab; parenteral
16.8
6.8
10
6
T90
ICPC
Diabetes non-insulin dependent
1.6
6.7
198
1372
R03BA02
ATC
budesonide; inhalant
1.7
6.7
139
884
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
7.2
6.7
15
21
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
6.7
209
1468
WX204
NOMESCO Finland
Axillary plexus blockaced
2.9
6.7
30
105
NGH20
NOMESCO Finland
Reduction of dislocation of knee joint, open
22.7
6.7
9
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.2
6.7
56
265
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.7
6.7
118
720
N06AX03
ATC
mianserin; oral
2.4
6.6
44
188
R07.0
ICD-10 Finland
Pain in throat
2.3
6.6
49
220
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
6.6
299
2267
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
12.3
6.6
11
9
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
3.3
6.6
24
74
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.2
6.6
55
260
ND1BG
NOMESCO Finland
Wrist and hand MRI examination with high intensity magnet
8.8
6.6
13
15
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
6.6
224
1604
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
6.6
137
874
S82.8
ICD-10 Finland
Fractures of other parts of lower leg
2.7
6.5
34
129
ZYC01
NOMESCO Finland
Remote contact by phone
2.3
6.5
48
215
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.5
6.5
267
1986
A46
ICD-10 Finland
Erysipelas
1.8
6.5
109
655
D01AC02
ATC
miconazole; topical
2.0
6.5
65
330
ACC53
NOMESCO Finland
Release of ulnar nerve
4.0
6.5
18
46
TKC22
NOMESCO Finland
Catheterisation instruction
3.4
6.4
22
65
K02.1
ICD-10 Finland
Caries of dentine
1.4
6.4
469
3877
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.0
6.4
71
373
NDG30
NOMESCO Finland
Fusion of wrist, total
70.3
6.4
7
*
NHG22
NOMESCO Finland
Fusion of subtalar joint
70.3
6.4
7
*
NHE20
NOMESCO Finland
Plastic repair of capsule or ligament of ankle joint with transplant
70.3
6.4
7
*
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
70.3
6.4
7
*
NK4EA
NOMESCO Finland
Joint X-ray examintion with load or wrench not elsewhere classified
70.3
6.4
7
*
ZZH31
NOMESCO Finland
Bone allograft, small pieces
14.4
6.4
10
7
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
6.4
445
3649
R52.1
ICD-10 Finland
Chronic intractable pain
8.2
6.3
13
16
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
6.3
302
2310
J02AC01
ATC
fluconazole; systemic
1.5
6.3
292
2220
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
6.3
242
1774
NH3EA
NOMESCO Finland
Feet X-ray examination with load
18.2
6.3
9
5
M87.0
ICD-10 Finland
Idiopathic aseptic necrosis of bone
18.2
6.3
9
5
349
Kela drug reimbursment
Febuxostat
+∞
6.3
6
*
7176A
ICD-9 Finland
Internal derangement of knee, Loose body in knee
+∞
6.3
6
*
71309
ICD-8 Finland
Osteo-arthritis and allied conditions, Arthritis (arthrosis) NUD
+∞
6.3
6
*
NGF10
NOMESCO Finland
Total synovectomy of knee, open
+∞
6.3
6
*
7183F
ICD-9 Finland
Other derangement of joint, Recurrent dislocation of joint[LUXATIO HABITUALIS, POLVI]
+∞
6.3
6
*
NGB30
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part - connected prosthesis
+∞
6.3
6
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.2
6.2
54
259
WX702
NOMESCO Finland
Supraglottic ventilation device
2.3
6.2
45
200
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
26.9
6.2
8
*
E66.8
ICD-10 Finland
Other obesity
2.4
6.2
40
169
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
6.2
374
2984
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.8
6.2
94
548
R05FB02
ATC
cough suppressants and expectorants; systemic
1.4
6.2
296
2264
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
3.6
6.2
20
57
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.2
6.2
51
240
L91
ICPC
Osteoarthrosis other
6.3
6.2
15
24
L11
ICPC
Wrist symptom/complaint
2.0
6.2
62
315
M75.2
ICD-10 Finland
Bicipital tendinitis
3.4
6.2
21
62
8442A
ICD-9 Finland
Sprains and strains of knee and leg, Cruciate ligament of knee[DISTORSIO/DISTEN/RUPT.LIG.CRUCIATI ANTERIORIS GENUS]
7.7
6.1
13
17
RF220, ,
NOMESCO Finland
7.7
6.1
13
17
J01DA09
ATC
[U] cefadroxil
1.5
6.1
213
1529
C10AA05
ATC
atorvastatin; oral
1.4
6.1
349
2756
WX306
NOMESCO Finland
Lumbar epidural anesthesy
2.3
6.1
45
202
G57.6
ICD-10 Finland
Lesion of plantar nerve
4.2
6.1
16
39
R05FA02
ATC
opium derivatives and expectorants; systemic
1.4
6.1
310
2397
M01AC02
ATC
tenoxicam; systemic, rectal
2.5
6.1
37
152
R60.0
ICD-10 Finland
Localized oedema
1.9
6.1
81
454
92700
ICD-8 Finland
Contusion of hip, thigh, leg and ankle, Current injury
8.7
6.1
12
14
M18.0
ICD-10 Finland
Primary arthrosis of first carpometacarpal joints, bilateral
8.7
6.1
12
14
J01EA01
ATC
trimethoprim; systemic
1.5
6.1
187
1308
E0000UV, ,
ATC
1.4
6.1
316
2454
M84.1
ICD-10 Finland
Nonunion of fracture [pseudarthrosis]
6.7
6.0
14
21
M43.1
ICD-10 Finland
Spondylolisthesis
2.7
6.0
31
117
S01KA02
ATC
hypromellose; ophthalmic
3.9
6.0
17
44

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
42
40
10.94
38.66
1.6
1.1
10173.65
12938.14
e6/l
0.17
31
29
201
840
2.77
32.63
1.3
1.2
24.25
17.89
iu/ml
0.70
61
241
190
772
2.83
32.54
1.3
1.1
3.96
1.51
u/ml
0.64
83
324
31
29
11.02
28.78
1.4
1.0
—
—
—
0
0
650
5045
1.93
18.87
4.8
3.1
11.30
11.66
mm/h
0.26
617
4623
29
18
16.57
18.41
1.7
1.1
—
—
—
0
0
271
1650
1.90
16.46
2.9
2.4
2133.49
8794.08
umol/l
2.41
237
1456
688
5556
1.89
16.26
7.6
7.4
77.13
78.40
u/l
0.42
665
5241
438
3099
1.77
16.20
2.8
2.4
—
—
—
0
0
25
15
17.09
16.14
1.6
1.0
55.57
74.50
%
—
14
10
169
880
2.12
15.93
2.3
2.0
—
—
—
0
0
463
3389
1.72
14.71
5.6
5.0
0.04
0.04
e9/l
0.90
411
2890
334
2233
1.77
14.65
2.8
2.6
54.44
61.90
u/l
1.31
313
2070
462
3384
1.72
14.61
5.6
5.0
0.58
0.58
e9/l
0.07
408
2882
437
3153
1.72
14.59
5.9
5.6
—
—
—
0
0
137
682
2.18
14.41
1.2
1.3
420.00
504.96
titre
0.32
34
125
475
3516
1.71
14.36
5.7
5.3
0.20
0.19
e9/l
0.86
424
3039
470
3480
1.70
14.11
5.7
5.0
1.91
1.92
e9/l
0.09
421
3031
244
1516
1.82
13.53
1.7
1.7
0.93
1.25
mg/l
2.09
196
1158
539
4260
1.62
11.62
4.5
5.0
6.72
6.76
mmol/l
0.20
517
3996
827
7354
2.03
11.44
16.7
12.7
22.69
26.87
mg/l
2.68
700
5599
490
3821
1.59
10.89
5.2
6.9
11.07
11.85
umol/l
0.51
468
3631
584
4758
1.60
10.67
4.7
3.7
—
—
—
0
0
299
2081
1.64
10.60
2.2
2.1
270.57
283.65
u/l
0.06
287
1960
333
2408
1.59
9.97
3.9
3.4
52.36
143.12
e6/l
1.77
262
1711
41
139
3.04
9.56
1.1
1.1
—
—
—
0
0
415
3181
1.54
9.50
5.7
5.2
2.88
2.84
%
0.12
387
2980
51
198
2.67
9.30
1.1
1.2
0.36
0.90
u/ml
—
9
14
425
3286
1.53
9.28
14.1
13.6
1.20
1.25
inr
0.53
132
956
272
1909
1.60
9.08
3.4
2.9
0.20
0.57
e6/l
4.86
228
1431
554
4548
1.53
9.06
4.9
3.9
2.60
1821.38
e6/l
—
5
66
405
3111
1.53
9.05
5.6
6.4
1.21
1.21
mmol/l
0.51
381
2822
434
3386
1.52
9.00
4.2
3.2
0.00
0.00
estimate
0.50
91
630
437
3416
1.52
8.97
4.1
3.2
0.00
0.01
estimate
0.80
84
564
282
2001
1.58
8.97
3.8
4.0
7.40
7.40
ph
0.06
59
388
438
3427
1.52
8.94
6.8
7.2
1.21
1.21
mmol/l
0.49
391
2911
401
3085
1.52
8.83
5.6
5.1
0.69
0.67
%
0.37
374
2882
504
4078
1.51
8.67
8.2
9.1
4.03
4.10
e9/l
0.31
452
3535
416
3235
1.51
8.66
5.7
5.0
56.86
57.16
%
0.20
389
3045
271
1924
1.57
8.53
4.4
4.3
—
—
—
0
0
396
3057
1.51
8.48
5.1
5.1
35.73
35.58
g/l
0.21
375
2849
430
3380
1.50
8.42
5.2
4.4
0.00
0.00
estimate
0.50
82
601
264
1869
1.57
8.39
3.3
2.8
—
—
—
0
0
410
3197
1.50
8.32
6.4
5.5
8.59
8.71
%
0.37
385
2998
625
5318
1.52
8.24
3.7
3.6
—
—
—
0
0
419
3287
1.50
8.23
5.9
5.2
28.27
27.76
%
0.43
393
3093
289
2107
1.54
8.00
3.6
2.9
25.08
66.75
e6/l
3.76
238
1599
78
393
2.07
7.90
1.4
1.2
506.39
264.41
u/ml
0.61
73
358
253
1812
1.54
7.52
4.7
3.3
0.00
0.01
estimate
1.08
84
576
358
2757
1.48
7.52
2.4
2.1
74.86
76.12
nmol/l
0.38
335
2477
206
1431
1.56
6.96
2.9
2.4
6.06
5.97
e6/l
0.03
188
1273
228
1632
1.52
6.70
2.3
1.9
3.12
2.87
mg/l
0.65
203
1347
136
862
1.68
6.67
2.4
2.5
22.57
24.06
%
0.55
126
740
398
3185
1.43
6.60
9.0
8.5
0.00
0.00
e9/l
0.42
344
2572
844
7823
1.77
6.58
18.0
15.1
139.54
139.72
mmol/l
1.25
835
7595
349
2728
1.44
6.57
3.8
3.4
40.47
58.88
ng/l
0.58
257
1876
846
7855
1.76
6.45
18.4
15.1
3.99
3.97
mmol/l
1.02
836
7616
362
2857
1.43
6.44
3.2
2.5
127.07
152.62
ug/l
1.29
346
2643
170
1150
1.58
6.41
2.9
2.6
1.17
1.00
e6/l
0.25
112
650
281
2123
1.46
6.28
2.6
2.3
—
—
—
0
0
632
5530
1.44
6.17
4.3
3.7
14.80
14.76
pmol/l
0.14
587
5023
846
7879
1.73
6.05
15.6
12.0
—
—
—
0
0
284
2172
1.44
5.89
3.1
3.1
429.29
469.46
mg/l
0.05
207
1363
117
742
1.66
5.71
1.8
1.7
—
—
—
0
0
216
1579
1.48
5.64
1.5
1.5
20.80
20.45
nmol/l
0.13
192
1350
352
2816
1.40
5.61
1.9
1.9
93.67
93.06
pmol/l
0.09
191
1490
208
1519
1.47
5.44
3.9
3.2
—
—
—
0
0
340
2715
1.40
5.44
3.4
3.0
5.57
5.82
ph
1.19
21
246
299
2338
1.41
5.40
2.6
3.3
30.53
33.01
u/l
0.97
270
2227
744
6773
1.47
5.40
5.1
4.4
1.87
2.37
mu/l
0.92
703
6172
716
6481
1.44
5.27
18.6
15.4
15.08
14.77
%
0.68
709
6355
291
2273
1.41
5.26
3.5
3.0
7.69
7.79
mmol/l
0.13
259
1932
244
1849
1.43
5.23
3.9
3.8
93.75
89.89
%
1.59
236
1804
260
1994
1.42
5.21
3.6
2.8
—
—
—
0
0
73
419
1.80
5.09
2.7
3.2
4.26
7.96
e9/l
1.31
58
345
80
472
1.76
5.09
3.8
4.2
0.05
0.14
%
0.60
21
143
292
2294
1.40
5.08
3.9
3.6
20.26
8.95
mg/mmol
0.46
205
1446
765
7028
1.47
5.05
6.3
5.3
40.51
39.92
mmol/mol
0.91
725
6485
10
13
7.76
4.85
1.1
1.0
—
—
—
0
0
213
1613
1.41
4.52
2.6
2.2
—
—
—
0
0
172
1257
1.45
4.43
1.3
1.5
2.22
2.49
g/l
1.66
110
769
117
799
1.53
4.20
1.4
1.4
—
—
—
0
0
80
499
1.66
4.19
3.8
4.2
0.10
0.13
%
0.20
21
172
196
1481
1.41
4.19
4.9
3.3
1.02
1.02
kg/l
0.42
26
200
28
122
2.33
4.14
2.1
2.3
313.07
2501.69
u/l
—
7
47
49
266
1.89
4.11
8.9
8.9
—
—
—
0
0
61
355
1.77
4.10
1.3
1.2
—
—
—
0
0
69
419
1.70
4.01
2.8
3.6
7.41
7.42
ph
0.13
14
49
51
284
1.84
3.97
2.6
1.6
—
—
—
0
0
225
1756
1.37
3.94
7.2
6.6
—
—
—
0
0
83
533
1.61
3.89
3.7
4.2
1.33
1.02
%
0.39
24
205
184
1392
1.40
3.89
3.3
2.7
547.25
543.77
mosm/kgh2o
0.07
161
1183
77
490
1.62
3.75
3.6
4.1
0.90
0.79
%
0.13
24
176
131
946
1.45
3.58
6.2
5.9
1.06
1.03
mmol/l
0.42
125
874
108
751
1.49
3.57
5.9
9.7
95.25
95.74
%
0.25
102
728
86
569
1.56
3.57
3.6
3.0
—
—
—
0
0
79
515
1.58
3.50
1.4
1.4
—
—
—
0
0
111
783
1.47
3.43
1.5
1.6
—
—
—
0
0
186
1443
1.36
3.35
1.3
1.2
1.69
2.06
u/ml
0.19
47
385
147
1098
1.40
3.34
3.3
2.7
1.75
1.90
e6/l
0.13
91
596
28
137
2.08
3.19
1.8
2.4
130.09
128.65
g/l
0.10
22
101
54
329
1.68
3.15
2.6
2.3
—
—
—
0
0
108
775
1.44
3.07
2.0
2.2
270.74
152.73
ug/g
0.73
79
624
27
134
2.04
2.98
1.0
1.3
—
—
—
0
0
852
8161
1.47
2.98
11.5
9.2
26.99
26.94
u/l
0.03
839
7867
86
594
1.49
2.97
2.5
2.2
12.86
12.77
nmol/l
0.04
78
532
29
150
1.96
2.87
1.2
1.3
243.18
668.58
e6/l
0.37
22
118
29
150
1.96
2.87
1.2
1.2
2.18
5.16
e6/l
1.12
22
115
550
4988
1.25
2.80
3.4
3.0
51.27
52.20
u/l
0.09
523
4677
74
503
1.51
2.77
1.1
1.1
—
—
—
0
0
73
496
1.51
2.74
3.7
3.8
115.40
93.77
ng/l
0.39
65
429
113
839
1.39
2.67
5.8
9.2
5.10
5.10
kpa
0.01
107
804
113
839
1.39
2.67
5.7
9.2
12.07
12.27
kpa
0.13
107
807
880
8517
1.51
2.54
23.8
18.7
40.65
40.40
%
0.59
838
7941
91
658
1.42
2.51
1.5
1.6
—
—
—
0
0
20
95
2.13
2.50
1.2
1.2
—
—
—
0
0
16
69
2.34
2.49
1.6
2.0
—
—
—
0
0
880
8521
1.51
2.49
24.0
18.5
251.44
248.84
e9/l
0.55
870
8255
33
188
1.78
2.48
1.5
1.4
168.31
276.70
ug/g
1.69
14
115
110
824
1.38
2.48
2.3
2.8
9.03
8.72
umol/l
0.04
96
718
48
304
1.61
2.46
2.8
3.6
—
—
—
0
0
10
32
3.15
2.44
1.8
3.7
—
—
—
0
0
880
8526
1.50
2.42
24.0
18.5
6.77
6.61
e9/l
1.51
869
8244
816
7808
1.34
2.41
5.1
4.7
2.70
2.82
mmol/l
3.14
769
7212
880
8527
1.49
2.41
24.0
18.5
4.53
4.53
e12/l
0.08
867
8243
880
8530
1.49
2.37
24.1
18.5
136.09
136.87
g/l
0.84
875
8381
802
7669
1.31
2.27
4.5
4.2
4.63
4.72
mmol/l
1.54
757
7117
20
99
2.04
2.27
1.1
1.5
220.10
61.74
mu/l
0.82
20
89
0
59
0.00
2.25
0.0
18.2
—
1539.51
—
0
59
69
486
1.45
2.21
3.3
6.0
—
—
—
0
0
8
24
3.35
2.18
3.9
11.3
29.88
25.87
mmol/l
—
8
24
14
61
2.31
2.15
1.5
1.5
—
—
—
0
0
228
1928
1.24
2.10
2.9
3.0
1017.31
1288.98
ng/l
0.60
193
1637
281
2431
1.22
2.08
3.2
3.9
2.35
2.36
mmol/l
0.15
260
2169
59
410
1.47
2.04
5.7
2.6
—
—
—
0
0
22
118
1.89
2.03
1.5
1.4
—
—
—
0
0
14
63
2.24
2.01
1.9
1.2
2.30
1.54
nmol/l
0.85
14
58
41
264
1.58
2.01
1.7
1.9
23.47
21.98
s
0.31
34
235
78
574
1.39
1.99
3.0
3.7
1.23
1.23
mmol/l
0.10
69
487
29
171
1.72
1.98
1.3
1.4
8.32
9.67
u/l
0.26
21
134
172
1418
1.26
1.98
3.6
3.6
147.68
522.55
ng/l
2.99
131
1089
44
290
1.54
1.96
2.6
2.7
—
—
—
0
0
793
7607
1.27
1.93
4.4
4.2
1.44
1.46
mmol/l
0.55
746
7018
20
106
1.91
1.92
2.2
3.7
57.85
56.61
%
0.17
20
106
19
99
1.94
1.91
2.2
2.1
1.03
1.02
g/l
0.01
14
75
19
99
1.94
1.91
2.4
2.4
—
—
—
0
0
59
418
1.44
1.87
2.0
2.8
—
—
—
0
0
777
7447
1.25
1.84
4.7
4.3
6.02
5.96
mmol/l
0.73
732
6806
19
101
1.90
1.81
2.3
3.1
4.40
4.14
e9/l
0.20
19
101
30
184
1.65
1.80
2.3
2.3
86.01
147.78
ug/min
0.42
20
111
57
406
1.43
1.77
1.4
1.6
—
—
—
0
0
9
36
2.51
1.74
1.3
1.3
—
—
—
0
0
118
944
1.29
1.74
1.2
1.2
—
—
—
0
0
101
793
1.31
1.72
1.2
1.3
—
—
—
0
0
43
292
1.50
1.70
3.0
4.2
—
—
—
0
0
10
40
2.52
1.67
1.2
1.1
151.40
143.54
nmol/l
—
10
40
218
1879
1.21
1.65
4.1
2.9
—
—
—
0
0
106
844
1.29
1.63
6.0
9.1
1.33
1.08
mmol/l
0.24
84
675
235
2045
1.20
1.61
4.1
3.6
—
—
—
0
0
16
84
1.92
1.60
1.1
1.5
—
—
nmol/l
—
0
0
88
686
1.31
1.59
2.5
2.4
30.43
41.47
u/l
1.99
70
588
40
272
1.49
1.59
1.1
1.3
—
7.82
—
0
6
29
184
1.59
1.56
1.1
1.2
—
—
—
0
0
24
146
1.66
1.52
3.8
2.2
—
—
—
0
0
15
81
1.87
1.40
1.1
1.0
1.71
8.22
u/ml
—
7
38
9
40
2.26
1.40
1.0
1.1
—
—
—
0
0
23
142
1.64
1.39
1.9
2.5
16.87
16.38
%
0.25
15
73
157
1334
1.21
1.38
3.0
3.3
2.46
2.46
mmol/l
0.02
146
1193
64
488
1.33
1.37
1.3
1.2
—
—
—
0
0
51
375
1.38
1.37
3.2
2.5
0.28
0.21
e6/l
0.22
51
364
15
82
1.84
1.36
9.0
1.7
—
—
—
0
0
11
54
2.05
1.33
1.8
1.2
156.78
184.76
pmol/l
0.51
11
54
75
588
1.30
1.33
2.4
2.7
99.97
189.82
ng/l
3.05
70
535
144
1219
1.21
1.32
1.6
1.6
1316.49
1175.47
nmol/l
0.69
110
933
19
114
1.68
1.29
3.9
2.9
—
—
—
0
0
760
7337
1.19
1.28
4.0
3.8
1.39
1.31
mmol/l
1.74
706
6728
29
195
1.50
1.25
4.1
3.1
—
—
—
0
0
143
1217
1.21
1.25
3.1
3.6
0.81
0.82
mmol/l
0.99
135
1158
318
2891
1.15
1.25
4.5
4.5
2.03
2.99
ug/l
1.60
297
2600
15
85
1.78
1.23
1.1
1.5
—
—
—
0
0
28
188
1.50
1.22
5.3
1.5
—
—
—
0
0
11
56
1.98
1.22
1.0
1.2
—
—
—
0
0
269
2976
0.87
1.22
2.8
2.8
—
—
—
0
0
28
189
1.50
1.20
5.3
1.5
—
—
—
0
0
13
71
1.84
1.20
1.0
1.2
—
—
—
0
0
8
38
2.11
1.18
1.6
1.5
—
—
—
0
0
28
190
1.49
1.17
5.3
1.5
—
—
—
0
0
17
102
1.68
1.16
1.1
1.1
1.72
2.91
u/ml
—
5
57
8
39
2.06
1.15
1.0
1.3
—
—
—
0
0
5
20
2.51
1.15
3.0
2.2
11.40
12.67
%
—
5
15
7
31
2.27
1.10
1.7
2.8
—
—
—
0
0
27
185
1.47
1.09
2.1
2.4
10.26
11.12
mg/l
0.30
27
166
27
186
1.46
1.07
5.5
1.5
—
—
—
0
0
7
33
2.13
1.05
1.7
3.5
—
—
—
0
0
7
33
2.13
1.05
2.3
3.9
306.43
1127.48
u/ml
—
7
33
5
22
2.28
1.03
1.0
1.6
—
—
—
0
0
11
60
1.84
1.03
1.3
1.2
—
—
—
0
0
52
404
1.30
1.03
7.0
13.5
—
—
—
0
0
10
53
1.90
1.01
1.1
1.7
—
—
—
0
0
171
1509
1.16
1.00
1.6
1.6
423.70
33518654.91
pmol/l
1.70
154
1262
20
131
1.54
1.00
1.5
2.1
—
—
—
0
0
9
49
1.84
0.98
1.9
2.4
—
—
—
0
0
0
30
0.00
0.97
0.0
1.3
—
13.04
—
0
20
22
150
1.48
0.93
3.9
3.6
—
—
—
0
0
220
1989
1.14
0.92
1.7
1.6
1.53
1.41
mmol/l
0.92
194
1652
9
52
1.74
0.92
1.3
1.2
—
—
—
0
0
6
28
2.15
0.91
1.0
14.9
—
—
—
0
0
12
71
1.70
0.89
1.1
1.3
—
—
—
0
0
86
724
1.21
0.88
1.7
2.5
1.78
1.77
%
0.03
77
641
40
513
0.77
0.86
1.4
1.5
—
—
—
0
0
6
32
1.88
0.82
7.3
3.2
40.72
30.54
mu/l
—
6
32
24
172
1.41
0.81
6.0
1.6
—
—
—
0
0
82
695
1.20
0.80
1.4
1.4
—
—
—
0
0
88
751
1.19
0.80
1.6
1.6
—
—
—
0
0
6
33
1.82
0.79
1.0
1.3
4.52
8.12
u/l
—
6
27
15
98
1.54
0.78
1.3
1.2
2.00
4.53
u/ml
—
6
45
49
394
1.26
0.78
2.0
3.6
4.40
4.48
pmol/l
0.26
39
359
14
91
1.55
0.75
1.0
1.1
—
—
—
0
0
5
24
2.09
0.74
1.6
3.0
—
—
—
0
0
42
334
1.27
0.74
1.0
1.1
—
—
—
0
0
43
343
1.27
0.74
3.9
3.7
—
—
—
0
0
68
803
0.83
0.73
1.4
1.4
—
—
—
0
0
65
545
1.21
0.72
1.9
2.7
65.09
69.52
e9/l
0.54
48
413
14
92
1.53
0.72
1.1
1.4
—
—
—
0
0
13
84
1.56
0.72
1.5
1.2
—
—
—
0
0
7
41
1.71
0.70
1.3
2.3
—
—
—
0
0
16
110
1.46
0.68
1.1
1.2
—
—
—
0
0
5
27
1.86
0.68
1.2
1.0
—
0.25
—
0
6
7
42
1.67
0.68
1.6
1.2
0.75
1.34
nmol/l
—
7
33
315
2959
1.10
0.67
2.2
2.0
—
—
—
0
0
5
28
1.79
0.66
1.0
1.2
—
40.50
—
0
8
111
985
1.14
0.64
1.7
1.7
—
—
—
0
0
5
29
1.73
0.64
1.6
2.2
43.00
50.38
umol/l
—
5
21
5
29
1.73
0.64
1.2
1.1
—
—
—
0
0
31
243
1.29
0.63
1.5
1.7
—
—
—
0
0
28
217
1.30
0.62
1.1
1.1
—
—
—
0
0
8
49
1.64
0.62
1.5
1.8
39.65
37.55
%
—
8
49
24
182
1.33
0.62
1.1
1.2
—
1088.57
—
0
7
184
1691
1.11
0.61
3.1
2.8
0.64
0.80
ug/l
1.57
115
1063
8
51
1.57
0.60
1.0
1.5
—
—
—
0
0
23
174
1.33
0.60
1.8
2.0
1.86
4.53
iu/l
—
8
66
74
641
1.17
0.60
2.2
2.4
6.58
8.10
ug/l
0.27
66
568
45
373
1.22
0.59
2.8
3.5
25.38
24.99
mmol/l
0.27
45
362
23
175
1.32
0.58
1.1
1.2
—
—
—
0
0
0
23
0.00
0.58
0.0
1.1
—
318.00
—
0
15
19
141
1.35
0.56
7.4
1.5
—
—
—
0
0
76
664
1.16
0.56
3.3
4.4
—
—
—
0
0
24
186
1.30
0.55
1.3
1.2
—
—
—
0
0
13
182
0.71
0.54
1.3
1.4
—
—
—
0
0
11
74
1.49
0.53
2.3
2.5
0.78
2.31
g/24h
—
5
40
31
250
1.25
0.53
4.1
3.7
0.11
0.26
g/l
3.06
12
112
6
97
0.62
0.52
2.8
2.7
—
—
—
0
0
54
466
1.17
0.48
2.5
3.4
129.72
129.73
g/l
0.00
54
457
7
46
1.53
0.48
1.1
1.3
—
—
—
0
0
17
128
1.33
0.48
1.9
2.9
—
—
—
0
0
20
155
1.30
0.47
3.8
4.1
3.80
2.48
mmol/l
0.41
15
108
20
155
1.30
0.47
3.9
4.1
5.25
5.05
kpa
0.44
20
149
15
111
1.36
0.47
1.1
1.1
—
—
—
0
0
5
83
0.60
0.46
1.4
1.4
—
—
—
0
0
213
2002
1.08
0.45
1.4
1.4
—
—
—
0
0
19
147
1.30
0.45
2.4
4.5
—
—
—
0
0
67
592
1.14
0.45
1.3
1.3
—
—
—
0
0
21
166
1.27
0.43
4.8
3.3
19.50
25.70
mg/l
—
8
103
0
15
0.00
0.41
0.0
1.1
—
1.29
—
0
10
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
8
59
1.36
0.41
1.1
1.3
1.56
1.57
g/l
—
8
59
15
114
1.32
0.41
1.6
1.7
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.5
—
2.55
—
0
17
10
71
1.41
0.39
3.8
3.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
24.88
—
0
13
11
80
1.38
0.38
1.1
1.1
—
—
—
0
0
10
72
1.39
0.37
1.9
1.8
—
—
—
0
0
88
804
1.10
0.36
3.7
4.7
64.81
26.40
ug/l
0.28
70
669
13
99
1.32
0.35
1.2
1.1
—
10.40
—
0
6
5
80
0.62
0.35
1.4
1.4
—
—
—
0
0
5
80
0.62
0.35
1.4
1.4
—
—
—
0
0
48
425
1.14
0.34
1.5
1.6
—
—
—
0
0
12
91
1.32
0.34
1.8
2.4
33.33
32.03
pg
0.51
12
91
6
46
1.31
0.33
1.0
1.0
—
—
—
0
0
33
286
1.16
0.31
1.7
2.1
0.63
1.48
ug/l
1.08
27
264
64
581
1.11
0.31
4.1
3.4
—
—
—
0
0
19
156
1.22
0.31
4.0
4.3
7.96
8.54
kpa
0.72
19
150
13
102
1.28
0.30
1.8
2.1
—
—
—
0
0
8
107
0.75
0.29
1.5
2.6
—
—
—
0
0
8
63
1.27
0.27
1.0
1.1
—
—
—
0
0
9
117
0.77
0.27
3.2
2.7
10.57
8.71
u/ml
—
9
112
68
626
1.09
0.26
7.8
9.5
—
—
—
0
0
5
71
0.70
0.26
1.0
4.6
—
—
—
0
0
5
74
0.67
0.26
1.2
1.2
277.20
278.32
mosm/kgh2o
—
5
53
38
340
1.12
0.25
3.6
3.7
24.72
24.13
mmol/l
0.61
38
330
6
81
0.74
0.24
1.3
1.1
—
—
—
0
0
5
42
1.19
0.21
1.0
1.0
—
—
—
0
0
21
182
1.16
0.21
1.2
1.3
135.30
272.63
miu/ml
—
10
83
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
6.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
15
126
1.19
0.21
2.3
2.0
—
—
—
0
0
0
13
0.00
0.21
0.0
3.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
15
176
0.85
0.20
2.3
3.1
—
—
—
0
0
6
50
1.20
0.19
1.5
1.2
—
—
—
0
0
22
193
1.14
0.19
1.5
1.6
—
—
—
0
0
74
695
1.07
0.19
3.4
3.7
2.46
1.89
mmol/l
0.76
66
559
6
53
1.13
0.18
2.7
4.1
—
—
—
0
0
12
100
1.20
0.18
1.0
1.0
—
—
—
0
0
7
60
1.17
0.18
1.0
1.3
—
—
—
0
0
22
195
1.13
0.17
3.6
3.9
7.43
7.42
ph
0.38
22
166
16
184
0.87
0.17
1.2
1.2
—
—
—
0
0
5
68
0.73
0.17
1.0
1.3
—
—
—
0
0
5
70
0.71
0.16
2.0
2.6
—
—
—
0
0
8
68
1.18
0.16
1.1
1.4
1.02
0.99
g/l
—
8
68
9
81
1.11
0.15
1.1
1.4
—
—
—
0
0
74
704
1.06
0.14
1.4
1.4
—
—
—
0
0
43
460
0.93
0.14
1.2
1.2
204.43
151.76
iu/ml
0.28
15
173
14
124
1.13
0.11
1.3
1.3
—
—
—
0
0
98
947
1.04
0.11
1.3
1.3
—
—
—
0
0
21
192
1.10
0.11
3.1
5.0
—
—
—
0
0
22
202
1.09
0.10
1.4
1.7
293.59
330.25
mu/l
0.24
22
191
5
46
1.09
0.09
2.6
2.5
927.00
595.76
e6/l
—
5
46
5
62
0.81
0.08
1.8
1.1
—
—
—
0
0
30
283
1.06
0.08
1.2
1.2
—
—
—
0
0
6
71
0.84
0.07
1.3
1.3
—
—
—
0
0
8
74
1.08
0.07
1.8
2.7
—
—
—
0
0
7
80
0.87
0.07
1.1
1.1
—
—
—
0
0
42
438
0.96
0.07
7.1
8.7
24.99
24.72
mmol/l
0.15
42
431
9
86
1.05
0.07
2.8
2.8
—
—
—
0
0
12
132
0.91
0.06
1.2
1.4
—
—
—
0
0
12
132
0.91
0.06
1.5
1.9
4.09
5.16
mmol/24h
0.88
12
116
30
286
1.05
0.06
1.3
1.1
213.00
216.78
titre
—
5
9
32
308
1.04
0.04
3.2
3.8
84.85
12658.60
u/ml
0.82
25
269
40
409
0.98
0.02
1.6
1.6
—
—
—
0
0
14
134
1.05
0.00
1.9
1.6
—
—
—
0
0
10
104
0.96
0.00
2.0
4.2
0.20
1.42
%
—
10
93
11
107
1.03
0.00
1.3
1.1
—
—
—
0
0
11
107
1.03
0.00
1.3
1.1
—
—
—
0
0
6
65
0.92
0.00
1.8
4.0
59.00
55.65
%
—
6
55
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
7.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.8
—
—
—
0
0
7
73
0.96
-0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
2.18
—
0
9
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
-0.00
2.1
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_CARTILAGE and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
M13_CARTILAGE 1.362 [1.0, 1.85] 0.05
Birth year 0.98 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 796 males with M13_CARTILAGE died.

Mortality risk

Mortality risk for people of age

years, who have M13_CARTILAGE.

N-year risk Females Males
1 No data 0.249%
5 No data 1.259%
10 No data 3.205%
15 No data 5.826%
20 No data 9.971%

Relationships between endpoints

Index endpoint: M13_CARTILAGE – Other articular cartilage disorders

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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