corneal disease: A non-neoplastic or neoplastic disorder that affects the cornea. Representative examples include keratitis, bullous keratopathy, and squamous cell carcinoma.
Other and unspecified corneal deformities and disorders
DOID EFO Endpoint Browser PheWeb
H7_CORNEALNAS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1198 |
4. Check minimum number of eventsNone |
1198 |
5. Include endpointsNone |
1198 |
6. Filter based on genotype QC (FinnGen only) |
1198 |
Control definitions (FinnGen only)
- Control exclude
- H7_SCLERACORNEA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF6
Similar endpoints
↥List of similar endpoints to
Other and unspecified corneal deformities and disorders
based on the number of shared cases.
Similar with more cases:
- Other disorders of cornea
- Disorders of sclera, cornea, iris and ciliary body
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8787 | 4685 | 4066 |
| Only index persons | 8268 | 4439 | 3829 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.13 | 0.11 |
| Only index persons | 0.16 | 0.16 | 0.15 |
| Median age at first event (years) | |||
| Whole population | 46.79 | 50.05 | 42.97 |
| Only index persons | 46.07 | 49.15 | 42.49 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1198 | 718 | 480 |
| Unadjusted period prevalence (%) | 0.23 | 0.24 | 0.21 |
| Median age at first event (years) | 50.02 | 50.07 | 49.95 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1070
- Matched controls
- 10697
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H16.0
ICD-10 Finland
Corneal ulcer
101.0
323.0
349
51
H18.8
ICD-10 Finland
Other specified disorders of cornea
+∞
323.0
791
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
7.7
203.2
776
2721
H18.9
ICD-10 Finland
Disorder of cornea, unspecified
+∞
135.3
127
*
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
+∞
123.4
116
*
H16.9
ICD-10 Finland
Keratitis, unspecified
319.8
114.4
114
*
H18.7
ICD-10 Finland
Other corneal deformities
+∞
108.2
102
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
7.1
105.4
289
529
CG2T4
NOMESCO Finland
Topography assessment of cornea
173.1
105.4
109
7
Z94.7
ICD-10 Finland
Corneal transplant status
+∞
99.6
94
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
350.3
95.6
95
*
S01AD03
ATC
aciclovir; ophthalmic
16.8
93.2
153
105
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
143.6
87.5
92
7
H18.6
ICD-10 Finland
Keratoconus
+∞
84.5
80
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
5.4
70.0
233
520
3718X
ICD-9 Finland
Corneal opacity and other disorders of cornea, Other corneal disorders
+∞
67.4
64
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
3.2
66.1
480
2145
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
+∞
62.1
59
*
CGD10
NOMESCO Finland
Laser keratoplasty for error of refraction
59.2
61.6
72
13
H18.4
ICD-10 Finland
Corneal degeneration
632.9
61.4
60
*
H04.10
ICD-10 Finland
Dry eye syndrome
5.1
59.0
206
478
TCG10
NOMESCO Finland
Removal of sutures from cornea
144.8
52.3
55
*
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
+∞
51.5
49
*
CG2S4
NOMESCO Finland
Photography of cornea
142.0
51.3
54
*
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
256.4
48.4
49
*
3604
FHL
Penetration of the cornea
+∞
47.2
45
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.3
45.1
185
497
XCK10
NOMESCO Finland
Photography of fundus of eye
4.2
44.0
186
514
H18.1
ICD-10 Finland
Bullous keratopathy
+∞
41.9
40
*
S01ED01
ATC
timolol; ophthalmic
8.8
39.4
87
107
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.1
39.1
255
985
S05.0
ICD-10 Finland
Injury of conjunctiva and corneal abrasion without mention of foreign body
10.4
36.5
73
75
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
4.9
33.5
117
264
H16.2
ICD-10 Finland
Keratoconjunctivitis
93.1
32.9
36
*
H17.8
ICD-10 Finland
Other corneal scars and opacities
175.4
32.9
34
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.5
32.1
311
1506
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.8
32.1
147
430
H25.1
ICD-10 Finland
Senile nuclear cataract
2.7
31.8
264
1172
S01ED51
ATC
timolol, combinations; ophthalmic
4.6
31.5
116
277
3716A
ICD-9 Finland
Corneal opacity and other disorders of cornea, Keratoconus
+∞
31.4
30
*
H57.1
ICD-10 Finland
Ocular pain
7.5
31.4
76
108
3619
FHL
Other operations in this group, such as corneal refractive surgery
+∞
30.3
29
*
H16.8
ICD-10 Finland
Other keratitis
310.7
29.9
30
*
WX140
NOMESCO Finland
Parabulbar anesthesy
5.8
29.8
88
164
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
22.3
29.8
43
20
S01BC03
ATC
diclofenac; ophthalmic
9.5
29.7
62
69
H20.1
ICD-10 Finland
Chronic iridocyclitis
+∞
29.3
28
*
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
288.7
27.9
28
*
CGG11
NOMESCO Finland
Corneal cross-linking
+∞
27.2
26
*
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
8.7
26.6
58
70
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
6.3
26.0
71
120
H17.1
ICD-10 Finland
Other central corneal opacity
138.3
25.7
27
*
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
12.0
25.1
46
40
ZXA00
NOMESCO Finland
Right side
2.2
25.0
324
1769
ZXA05
NOMESCO Finland
Left side
2.2
24.4
303
1622
H19.1
ICD-10 Finland
Herpesviral keratitis and keratoconjunctivitis
+∞
24.0
23
*
CGE10
NOMESCO Finland
Keratectomy
+∞
23.0
22
*
H18.2
ICD-10 Finland
Other corneal oedema
+∞
23.0
22
*
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
9.3
23.0
48
54
H52.2
ICD-10 Finland
Astigmatism
8.9
21.5
46
54
ZXA10
NOMESCO Finland
Bilateral
2.3
20.8
223
1103
CG2Z4
NOMESCO Finland
Specialised imaging of cornea
112.2
20.6
22
*
114
Kela drug reimbursment
Glaucoma
3.3
20.4
106
341
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
+∞
19.8
19
*
9881
FHL
Bandage replacement, suture or spike removal, or the like in an operating room or anesthesia
+∞
19.8
19
*
S01EC01
ATC
acetazolamide; systemic
8.0
19.4
44
57
S01FA01
ATC
atropine; ophthalmic
31.9
19.3
25
8
S01EE01
ATC
latanoprost; ophthalmic
3.9
18.3
78
213
CJB10
NOMESCO Finland
Laser discission of secondary cataract
3.2
18.1
101
339
XCK00
NOMESCO Finland
Perimetry
3.2
18.1
98
325
A10AA01
ATC
NA
5.0
17.8
57
118
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
4.3
17.7
67
164
H26.4
ICD-10 Finland
After-cataract
2.9
17.4
112
414
WX002
NOMESCO Finland
Sedation and analgesia
2.1
16.8
227
1233
CGG31
NOMESCO Finland
Posterior corneal lamellar transplantation
+∞
16.7
16
*
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
3.3
16.7
85
269
A10AA02
ATC
NA
4.5
16.6
59
136
XCH00
NOMESCO Finland
Eye pressure measurement
4.3
16.4
62
152
H16.1
ICD-10 Finland
Other superficial keratitis without conjunctivitis
40.8
16.4
20
5
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
5.7
16.0
46
84
S01AX11
ATC
[U] ofloxacin; ophthalmic
4.5
15.9
57
133
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
13.2
15.7
27
21
CFD10
NOMESCO Finland
Repair of conjunctiva
+∞
15.7
15
*
H40.0
ICD-10 Finland
Glaucoma suspect
2.9
15.4
97
354
H26.2
ICD-10 Finland
Complicated cataract
11.5
15.3
28
25
H3603, E103
ICD-10 Finland
NA
9.4
15.2
31
34
S01EA03
ATC
apraclonidine; ophthalmic
13.3
15.2
26
20
S01XA18
ATC
ciclosporin; ophthalmic
20.4
15.1
22
11
F29
ICPC
Eye symptom/complaint other
2.8
14.4
99
382
F01
ICPC
Eye pain
4.7
14.3
48
105
T89
ICPC
Diabetes insulin dependent
3.8
14.1
60
165
S01FA04
ATC
cyclopentolate; ophthalmic
13.8
13.8
23
17
3710A
ICD-9 Finland
Corneal opacity and other disorders of cornea, Corneal scars and opacities
+∞
13.6
13
*
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
34.5
13.5
17
5
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
4.0
13.4
54
142
S01EC04
ATC
brinzolamide; ophthalmic
4.2
13.2
50
124
H26.02
ICD-10 Finland
Presenil cataract
4.5
12.9
45
103
TCG30
NOMESCO Finland
Imaging of anterior and posterior part of cornea
70.7
12.6
14
*
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
4.1
12.6
48
120
37103
ICD-8 Finland
Corneal opacity, Keratoconus
+∞
12.5
12
*
H18.0
ICD-10 Finland
Corneal pigmentations and deposits
+∞
12.5
12
*
CGD99
NOMESCO Finland
Other operation for error of refraction
+∞
12.5
12
*
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.2
12.3
64
207
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
14.5
12.3
20
14
H15.1
ICD-10 Finland
Episcleritis
16.1
12.2
19
12
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.8
12.1
80
303
H33.0
ICD-10 Finland
Retinal detachment with retinal break
4.6
12.0
41
92
S01AA12
ATC
tobramycin; ophthalmic
21.6
12.0
17
8
S01EX03
ATC
NA
6.2
11.9
31
51
S01GX01
ATC
cromoglicic acid; ophthalmic
1.8
11.7
218
1317
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
65.7
11.6
13
*
H04AA01
ATC
glucagon; nasal, parenteral
4.8
11.6
38
82
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
4.5
11.5
40
92
H16.3
ICD-10 Finland
Interstitial and deep keratitis
+∞
11.5
11
*
H16.4
ICD-10 Finland
Corneal neovascularization
+∞
11.5
11
*
T86.8
ICD-10 Finland
Failure and rejection of other transplanted organs and tissues
+∞
11.5
11
*
S01BC05
ATC
ketorolac; ophthalmic
3.6
11.3
51
148
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
7.4
11.3
26
36
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
4.7
11.2
37
81
CGF10
NOMESCO Finland
Suture of laceration of cornea
43.8
10.9
13
*
A10AE04
ATC
insulin glargine; parenteral
2.3
10.8
106
494
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.5
10.8
88
376
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
3.3
10.8
53
165
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
9.7
10.8
21
22
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
7.4
10.5
24
33
S01KA02
ATC
hypromellose; ophthalmic
5.3
10.5
31
60
CGF35
NOMESCO Finland
Repair of cornea using graft
+∞
10.4
10
*
ZZL00
NOMESCO Finland
Free graft of amniotic membrane
+∞
10.4
10
*
3700A
ICD-9 Finland
Keratitis, Corneal ulcer
+∞
10.4
10
*
H43.1
ICD-10 Finland
Vitreous haemorrhage
4.7
10.1
33
72
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
3.1
9.9
52
171
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.7
9.8
234
1521
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.4
9.6
83
366
S01FA02
ATC
scopolamine; ophthalmic
10.1
9.5
18
18
CD2S4
NOMESCO Finland
Photography of eye
15.2
9.5
15
10
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
2.7
9.4
63
241
CGW99
NOMESCO Finland
Other operation on cornea or sclera
+∞
9.4
9
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
4.8
9.4
30
64
S01EC03
ATC
dorzolamide; ophthalmic
6.3
9.1
23
37
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.0
9.1
126
684
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
18.8
8.9
13
7
H27.0
ICD-10 Finland
Aphakia
18.8
8.9
13
7
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
24.2
8.9
12
5
S01EE05
ATC
tafluprost; ophthalmic
3.6
8.9
38
107
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
7.3
8.8
20
28
H15.0
ICD-10 Finland
Scleritis
50.4
8.7
10
*
L04AA01
ATC
[U] ciclosporin; systemic
4.4
8.7
30
70
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
7.4
8.5
19
26
E10
ICD-10 Finland
Type 1 diabetes mellitus
4.1
8.4
31
77
H18.3
ICD-10 Finland
Changes in corneal membranes
+∞
8.3
8
*
H19.2*B02.3
ICD-10 Finland
Keratitis and keratoconjunctivitis (interstitial) in zoster
+∞
8.3
8
*
3606
FHL
Keratophakic corneal surgery
+∞
8.3
8
*
H19.8*E85.80
ICD-10 Finland
Reticular keratitis in Meretoja's patients
+∞
8.3
8
*
37100
ICD-8 Finland
Corneal opacity, Cicatrix (nubecula, macula, leucoma) cornea
+∞
8.3
8
*
H02AB06
ATC
prednisolone; systemic
1.5
8.2
437
3417
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
6.9
8.1
19
28
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
9.0
8.1
16
18
J01DB01
ATC
cefalexin; oral
1.5
8.0
834
7458
A10AE06
ATC
insulin degludec; parenteral
3.1
8.0
41
134
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
7.9
267
1886
UJF32
NOMESCO Finland
Coloscopy
1.6
7.9
237
1627
S01EB01
ATC
pilocarpine; ophthalmic
10.9
7.8
14
13
D07AC01
ATC
betamethasone; topical
1.5
7.8
323
2387
103
Kela drug reimbursment
Diabetes, insulin-treated
1.6
7.8
239
1650
H40.9
ICD-10 Finland
Glaucoma, unspecified
5.1
7.7
23
46
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
45.3
7.7
9
*
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
45.3
7.7
9
*
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
45.3
7.7
9
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
7.6
462
3691
H11.0
ICD-10 Finland
Pterygium
8.1
7.6
16
20
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
25.2
7.6
10
*
J01FF01
ATC
clindamycin; systemic
1.5
7.5
261
1857
E85.80
ICD-10 Finland
Meretoja sick
80.6
7.4
8
*
H17.0
ICD-10 Finland
Adherent leukoma
+∞
7.3
7
*
H20.8
ICD-10 Finland
Other iridocyclitis
+∞
7.3
7
*
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.9
7.3
28
73
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
7.3
370
2848
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
3.7
7.1
29
80
CKC12
NOMESCO Finland
Photocoagulation of retina
2.8
7.1
45
168
H25.0
ICD-10 Finland
Senile incipient cataract
2.4
7.0
56
239
J01AA02
ATC
doxycycline; systemic
1.5
7.0
783
6972
H36.00
ICD-10 Finland
Diabetic background retinopathy
4.7
6.9
22
48
S01EE03
ATC
bimatoprost; ophthalmic
3.8
6.9
27
72
H52.1
ICD-10 Finland
Myopia
2.8
6.8
41
150
H10.4
ICD-10 Finland
Chronic conjunctivitis
6.7
6.8
16
24
D07AB08
ATC
desonide; topical
1.9
6.8
102
570
CKC10
NOMESCO Finland
Local photocoagulation of retina
4.7
6.7
21
45
B00.5
ICD-10 Finland
Herpesviral ocular disease
22.7
6.7
9
*
S01AX12
ATC
[U] norfloxacin; ophthalmic
8.8
6.6
13
15
J01MA02
ATC
ciprofloxacin; systemic
1.4
6.5
356
2762
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
4.2
6.5
23
56
CBH30
NOMESCO Finland
Tarsorraphy
70.2
6.4
7
*
CHB15
NOMESCO Finland
Puncture of anterior chamber of eye with replacement of aqueous
70.2
6.4
7
*
127
Kela drug reimbursment
Transplant complication
3.7
6.4
26
72
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
5.2
6.3
18
35
A10AE05
ATC
insulin detemir; parenteral
2.3
6.3
57
260
R03AC02
ATC
salbutamol; inhalant
1.4
6.3
499
4139
S01AA02
ATC
chlortetracycline; ophthalmic
9.3
6.3
12
13
H19.2
ICD-10 Finland
Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
+∞
6.3
6
*
3719X
ICD-9 Finland
Corneal opacity and other disorders of cornea, Unspecified corneal disorder
+∞
6.3
6
*
CGD40
NOMESCO Finland
Implantation of intracorneal ring segments
+∞
6.3
6
*
3714A
ICD-9 Finland
Corneal opacity and other disorders of cornea, Corneal degenerations
+∞
6.3
6
*
3642
FHL
Anterior vitrectomy
+∞
6.3
6
*
36399
ICD-8 Finland
Keratitis, Without mention of ulcer
+∞
6.3
6
*
H01.0
ICD-10 Finland
Blepharitis
2.3
6.2
54
242
R51.80
ICD-10 Finland
Headache
1.7
6.2
136
854
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
6.2
72
365
AN1
HP
Coronary angiography
1.9
6.2
92
514
R4120
NOMESCO Finland
Occupational therapy
2.1
6.1
63
305
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
7.7
6.1
13
17
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
2.9
6.0
35
125
J05AB11
ATC
valaciclovir; oral
1.7
6.0
128
801
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
36
85
4.34
14.15
1.3
1.3
—
—
—
0
0
860
7436
1.55
10.41
7.9
7.4
77.3
77.7
u/l
0.09
822
7006
1076
9861
1.90
10.24
15.9
13.1
22.0
22.9
mg/l
0.42
849
7742
370
2693
1.54
10.19
3.7
3.3
1197.5
389.6
mg/l
1.17
260
1687
385
2840
1.52
9.91
4.5
4.0
8.5
8.0
mg/mmol
0.06
263
1774
673
5573
1.47
9.67
9.6
9.0
4.1
4.0
e9/l
0.49
601
4903
390
2899
1.51
9.63
3.6
3.2
8.1
7.6
mmol/l
1.13
333
2446
1098
10169
1.96
9.53
18.5
14.9
4.0
4.0
mmol/l
0.44
1082
9886
21
46
4.63
9.08
1.4
1.2
—
—
—
0
0
1092
10133
1.88
8.86
18.4
14.8
139.7
139.7
mmol/l
0.34
1075
9867
822
7141
1.48
8.83
4.3
3.9
12.4
11.6
mm/h
0.83
769
6632
501
3989
1.44
8.45
5.7
4.8
36.0
35.8
g/l
0.19
473
3719
658
5537
1.42
7.99
5.6
4.6
6.9
6.7
mmol/l
1.72
613
5193
369
2801
1.46
7.91
2.2
2.1
129.8
243.2
u/l
2.55
351
2651
921
8275
1.49
7.61
20.0
16.0
13.7
13.6
%
0.13
907
8094
988
9052
1.52
6.98
5.4
4.7
1.9
2.0
mu/l
0.46
920
8351
226
1591
1.52
6.94
1.6
1.7
1185.4
1193.8
nmol/l
0.04
173
1195
715
6190
1.38
6.85
4.8
4.2
1239.7
2277.0
e6/l
0.42
13
88
1121
10608
1.88
6.82
11.8
9.9
26.5
26.9
u/l
0.43
1102
10279
558
4650
1.37
6.72
3.9
3.4
0.0
0.0
estimate
0.00
78
853
461
3727
1.39
6.68
2.1
1.9
96.0
97.0
pmol/l
0.17
241
1954
489
3992
1.38
6.68
2.7
2.2
78.6
76.1
nmol/l
1.07
444
3605
562
4717
1.36
6.34
3.9
3.4
0.0
0.0
estimate
0.80
72
830
557
4671
1.36
6.31
5.2
4.7
0.0
0.0
estimate
0.50
81
867
116
715
1.69
6.20
4.2
3.7
85.3
83.9
ng/l
0.07
99
631
70
374
1.93
6.00
1.2
1.2
1.2
1.2
u/ml
—
5
27
377
2997
1.38
5.90
3.1
2.5
55.0
57.4
u/l
0.55
349
2780
986
9125
1.46
5.70
6.9
5.4
41.4
39.4
mmol/mol
6.93
937
8517
841
7594
1.36
5.48
4.6
4.0
14.6
14.7
pmol/l
0.16
770
6964
403
3275
1.35
5.38
3.5
3.3
38.1
31.8
u/l
0.32
390
3114
314
2495
1.35
4.77
3.7
3.0
0.3
0.4
e6/l
1.96
258
1882
95
597
1.64
4.75
3.8
3.3
4.5
4.5
pmol/l
0.16
81
529
729
6516
1.30
4.68
3.1
3.0
—
—
—
0
0
282
2211
1.36
4.66
2.6
2.1
2.9
3.0
mg/l
0.69
250
1888
388
3194
1.32
4.60
3.4
3.5
2.4
2.4
mmol/l
0.03
343
2813
485
4124
1.30
4.50
3.3
2.7
103.5
120.7
ug/l
1.42
454
3831
156
1111
1.46
4.47
3.6
2.6
8.1
7.8
umol/l
0.06
135
964
104
682
1.57
4.38
3.3
2.9
192.1
190.0
ng/l
0.01
97
616
89
563
1.63
4.35
8.0
7.5
24.9
24.6
mmol/l
0.38
83
528
229
1758
1.37
4.30
4.6
3.6
194.0
428.8
ng/l
1.18
179
1311
59
336
1.80
4.23
2.1
2.3
7.0
7.4
g/l
0.77
40
256
59
336
1.80
4.23
2.1
2.3
—
—
—
0
0
59
336
1.80
4.23
2.1
2.3
4.0
3.8
g/l
0.27
39
240
152
1094
1.45
4.12
19.3
22.6
1.3
1.3
inr
0.02
15
142
27
116
2.36
4.10
1.0
1.1
—
—
—
0
0
164
1201
1.42
4.05
6.9
5.6
1.1
1.0
mmol/l
0.80
147
1104
528
4587
1.27
3.99
8.5
6.7
1.2
1.2
mmol/l
0.00
457
3881
274
2185
1.33
3.99
1.4
1.2
3.1
1.4
u/ml
0.56
85
611
262
2076
1.34
3.99
4.3
3.8
1.0
1.0
kg/l
0.59
32
293
309
2513
1.31
3.91
3.0
3.0
1226.1
1103.2
ng/l
0.24
281
2103
754
6847
1.27
3.90
3.2
3.1
43.9
48.2
u/l
1.07
720
6432
199
1517
1.37
3.89
3.1
2.6
0.9
1.2
e6/l
0.67
133
860
140
1004
1.45
3.88
1.9
1.8
—
—
—
0
0
142
1022
1.44
3.86
7.7
7.8
1.1
1.3
mmol/l
0.14
111
818
16
54
2.99
3.85
1.2
1.2
—
—
—
0
0
54
310
1.78
3.79
1.9
2.4
10.5
10.4
g/l
0.04
43
263
240
1897
1.33
3.70
3.0
2.5
4.4
6.3
e6/l
1.74
220
1685
264
2119
1.32
3.65
1.5
1.5
23.3
21.2
nmol/l
0.80
229
1811
566
4994
1.25
3.64
6.4
6.3
10.7
11.3
umol/l
0.74
540
4735
1144
11096
1.69
3.54
24.0
19.2
253.8
252.9
e9/l
0.17
1123
10837
54
317
1.74
3.53
2.2
2.4
3.0
3.1
g/l
0.44
39
246
312
2571
1.29
3.53
1.8
1.6
1.4
1.4
mmol/l
0.01
270
2183
479
4159
1.25
3.51
7.3
5.9
1.2
1.2
mmol/l
0.15
436
3773
418
3573
1.26
3.51
3.6
3.3
47.3
48.9
ng/l
0.04
285
2360
219
1727
1.33
3.42
1.3
1.3
145.2
31.1
iu/ml
0.41
79
540
1144
11105
1.67
3.41
24.0
19.2
4.5
4.5
e12/l
1.45
1117
10821
173
1317
1.37
3.41
2.7
2.3
2.3
2.4
g/l
0.10
163
1222
1056
10090
1.39
3.40
5.5
4.7
2.7
2.8
mmol/l
2.19
998
9375
1144
11106
1.67
3.39
24.0
19.2
6.8
6.7
e9/l
0.58
1121
10819
1144
11109
1.66
3.35
24.1
19.3
135.3
136.3
g/l
1.57
1132
10960
137
1008
1.41
3.31
1.9
1.8
—
—
—
0
0
183
1416
1.35
3.25
3.4
2.8
3.9
2.9
e6/l
0.26
117
765
1040
9931
1.36
3.20
5.1
4.3
4.7
4.7
mmol/l
2.13
987
9281
108
770
1.44
3.11
3.6
2.5
58.9
66.5
ml/min/173m2
1.36
49
311
101
711
1.46
3.11
2.4
3.0
67.1
67.1
g/l
0.03
95
649
1035
9888
1.34
3.08
4.9
4.2
1.4
1.5
mmol/l
1.54
983
9196
269
2215
1.28
3.03
1.6
1.7
1.4
1.1
mg/l
0.33
205
1673
183
1439
1.32
2.91
2.7
2.3
14.0
13.4
umol/l
0.54
170
1321
209
1674
1.30
2.91
3.0
3.1
2.5
2.4
mmol/l
0.22
187
1480
192
1521
1.31
2.90
4.2
3.3
0.8
0.8
mmol/l
0.20
180
1426
136
1025
1.37
2.87
8.1
7.7
5.1
5.1
kpa
0.10
128
984
136
1025
1.37
2.87
8.1
7.7
12.0
12.2
kpa
0.21
128
986
45
273
1.67
2.68
1.3
1.1
—
—
—
0
0
418
3658
1.22
2.68
4.0
3.6
—
—
—
0
0
147
1135
1.34
2.66
7.6
6.7
104.7
104.1
mmol/l
0.80
141
1109
294
2482
1.24
2.65
2.6
2.6
7754.5
5629.4
umol/l
0.26
266
2175
62
410
1.54
2.61
3.4
3.1
25.2
25.4
mmol/l
0.23
56
399
46
283
1.65
2.61
1.5
1.3
—
—
—
0
0
235
1951
1.25
2.45
1.7
1.7
449.9
37531135.5
pmol/l
2.16
204
1628
969
9248
1.25
2.40
18.2
13.9
40.0
40.2
%
0.33
720
6927
201
1646
1.27
2.35
1.3
1.3
11.2
11.9
u/ml
0.04
72
633
88
639
1.41
2.35
1.6
1.6
—
—
—
0
0
39
237
1.67
2.34
1.9
1.7
—
—
—
0
0
105
787
1.37
2.32
9.3
7.4
9.4
8.9
mmol/l
0.30
97
750
33
195
1.71
2.21
5.6
5.7
1493.7
320.3
iu/ml
—
6
30
996
9559
1.25
2.20
4.5
3.8
1.3
1.3
mmol/l
0.33
935
8841
210
1747
1.25
2.15
1.7
1.5
—
—
—
0
0
78
1057
0.72
2.11
1.7
1.7
—
—
—
0
0
147
1175
1.29
2.10
2.1
2.3
112.8
124.9
ug/g
0.20
111
942
152
1221
1.28
2.09
2.8
2.4
25.8
23.1
%
1.50
131
1039
54
368
1.49
2.04
1.4
2.0
1.7
1.5
g/l
1.07
44
322
105
806
1.33
2.02
5.1
3.5
2.1
2.0
mmol/l
0.20
84
654
45
298
1.53
1.95
1.2
1.3
317.7
227.1
miu/ml
0.64
13
145
76
558
1.39
1.94
1.5
1.5
—
—
—
0
0
27
159
1.71
1.86
4.4
5.8
337.0
372.9
umol/l
0.61
22
143
123
980
1.28
1.82
4.8
4.2
338.9
249.3
u/l
0.82
117
929
5
12
4.18
1.82
1.4
1.5
69.2
100.0
ng/l
—
5
12
23
130
1.78
1.82
1.0
1.1
8.1
4.4
u/ml
0.48
11
49
26
153
1.71
1.80
1.5
1.3
—
—
—
0
0
174
1447
1.24
1.80
1.9
1.8
—
—
—
0
0
975
9389
1.21
1.77
13.9
11.9
82.2
83.1
ml/min/173m2
0.61
832
7740
24
139
1.74
1.76
1.0
1.1
4.5
2.3
u/ml
0.38
12
54
29
179
1.64
1.71
1.5
1.7
—
—
—
0
0
10
42
2.39
1.68
1.7
3.0
580.5
778.7
u/ml
—
10
42
109
866
1.28
1.67
3.4
2.5
30.6
41.4
u/l
1.15
97
741
13
62
2.11
1.66
1.7
1.7
—
—
—
0
0
45
311
1.46
1.63
2.0
1.7
—
—
—
0
0
26
158
1.66
1.63
1.0
1.1
—
—
—
0
0
35
230
1.54
1.61
2.3
2.3
120.1
75.7
ug/min
0.26
21
145
8
32
2.51
1.60
5.1
4.5
—
—
—
0
0
42
289
1.47
1.57
1.2
1.1
—
—
—
0
0
17
92
1.86
1.56
5.4
4.9
34.5
59.0
u/ml
—
7
28
10
207
0.48
1.55
1.5
1.5
—
—
—
0
0
102
813
1.28
1.54
5.0
3.5
5.9
5.8
kpa
0.31
97
786
41
282
1.47
1.54
1.1
1.1
9.3
4.5
u/ml
—
5
34
5
15
3.34
1.52
3.2
3.5
—
—
—
0
0
7
27
2.60
1.51
1.3
3.1
—
—
—
0
0
7
27
2.60
1.51
1.3
3.1
—
—
—
0
0
44
309
1.44
1.49
1.7
2.2
372.5
408.6
ug/l
0.06
39
287
18
101
1.79
1.49
1.1
1.7
—
—
—
0
0
85
665
1.30
1.48
1.7
1.3
247.3
182.4
u/ml
0.43
79
613
10
203
0.49
1.48
1.3
1.4
—
—
—
0
0
10
203
0.49
1.48
1.3
1.4
—
—
—
0
0
9
37
2.44
1.48
3.1
1.8
65.3
52.6
ug/l
—
9
37
10
202
0.49
1.46
1.3
1.4
—
—
—
0
0
10
202
0.49
1.46
1.3
1.4
—
—
—
0
0
12
59
2.04
1.43
2.5
2.0
—
—
—
0
0
19
110
1.74
1.43
1.1
1.7
—
—
—
0
0
26
165
1.59
1.41
1.0
1.2
—
—
—
0
0
992
9619
1.18
1.40
4.9
4.3
6.0
5.9
mmol/l
2.39
931
8843
41
289
1.43
1.38
1.2
1.1
—
—
—
0
0
52
383
1.37
1.37
1.1
1.1
—
1.1
—
0
5
36
248
1.47
1.36
1.3
1.2
—
—
—
0
0
69
532
1.32
1.36
2.3
1.8
—
—
—
0
0
110
902
1.24
1.33
2.2
2.0
333.4
371.6
nmol/l
1.27
97
828
28
185
1.53
1.30
1.0
1.1
0.4
2.0
u/ml
1.61
12
78
19
114
1.68
1.28
1.5
1.5
—
—
—
0
0
8
35
2.29
1.27
1.0
1.4
—
—
—
0
0
26
170
1.54
1.26
1.2
1.1
—
12.1
—
0
13
12
63
1.91
1.23
1.3
2.1
452.3
601.0
e6/l
—
7
55
43
314
1.38
1.22
1.3
1.8
—
—
—
0
0
186
1621
1.17
1.21
1.5
1.4
—
—
—
0
0
56
427
1.33
1.21
2.0
2.1
39.5
39.4
u/l
0.01
50
377
97
1171
0.81
1.17
4.7
4.3
32.1
31.8
%
0.08
68
797
10
50
2.01
1.16
1.4
1.1
73.0
525.6
u/l
—
10
44
483
4505
1.12
1.16
4.9
3.9
—
—
—
0
0
245
2190
1.15
1.15
4.5
3.8
23.9
21.1
%
1.65
111
938
34
241
1.42
1.15
1.2
1.3
—
—
—
0
0
19
119
1.61
1.12
1.3
1.6
—
—
—
0
0
275
2483
1.14
1.12
4.2
3.8
0.0
0.0
estimate
1.28
74
842
16
96
1.68
1.10
1.1
1.5
54.3
55.2
%
—
8
66
8
41
1.96
1.09
1.0
1.1
106.3
237.9
iu/ml
—
8
41
39
287
1.37
1.08
2.2
2.1
4275.6
3260.0
u/l
0.16
16
115
85
698
1.23
1.06
2.1
2.3
13.6
13.0
nmol/l
0.33
72
630
7
33
2.13
1.05
1.6
1.2
10.9
8.5
ug/l
—
7
33
39
289
1.36
1.04
1.4
1.4
213.4
295.5
ug/g
1.64
24
169
22
147
1.51
1.01
1.0
1.0
0.8
1.9
u/ml
—
9
66
18
115
1.57
1.00
1.4
1.3
—
—
—
0
0
50
388
1.30
0.99
2.3
1.7
—
—
—
0
0
5
23
2.18
0.98
4.0
1.9
—
—
—
0
0
23
157
1.47
0.96
1.3
1.5
—
—
—
0
0
91
762
1.21
0.96
2.3
2.3
9.6
7.5
ug/l
0.21
82
676
296
2716
1.12
0.93
4.8
4.3
2.2
2.1
ug/l
0.09
273
2456
53
419
1.28
0.93
2.1
1.7
—
—
—
0
0
13
78
1.67
0.91
1.2
1.1
—
—
—
0
0
13
78
1.67
0.91
1.2
1.1
—
—
—
0
0
22
151
1.47
0.91
1.5
1.2
4.1
5.5
u/ml
—
8
59
8
42
1.91
0.88
1.0
1.0
1198.4
1774.0
miu/ml
—
8
42
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
35
263
1.34
0.88
2.5
3.0
0.4
0.4
u/ml
0.03
21
146
13
79
1.65
0.88
1.2
1.1
—
—
—
0
0
13
79
1.65
0.88
1.2
1.1
—
—
—
0
0
13
79
1.65
0.88
1.2
1.1
—
—
—
0
0
8
43
1.87
0.87
1.4
2.0
—
—
—
0
0
8
43
1.87
0.87
1.4
2.0
—
—
—
0
0
19
128
1.49
0.86
1.7
1.6
—
—
—
0
0
38
292
1.31
0.84
1.4
1.5
0.2
0.2
g/l
0.10
38
276
11
65
1.70
0.82
2.5
1.9
14.2
13.8
%
—
6
32
39
302
1.30
0.82
1.4
1.5
1.2
1.2
g/l
0.36
39
283
130
1143
1.15
0.80
8.3
6.8
—
—
—
0
0
10
58
1.73
0.79
1.3
1.2
—
—
—
0
0
15
98
1.54
0.78
2.0
1.8
—
—
—
0
0
21
148
1.43
0.78
1.6
1.2
2.9
3.9
u/ml
—
7
41
21
148
1.43
0.78
1.3
1.1
—
—
—
0
0
22
158
1.40
0.74
1.7
1.8
—
—
—
0
0
5
24
2.09
0.74
1.0
1.1
—
—
—
0
0
5
24
2.09
0.74
1.2
1.0
—
—
—
0
0
17
116
1.47
0.74
1.0
1.0
0.1
0.6
u/ml
—
5
30
25
184
1.37
0.74
1.3
1.4
—
—
—
0
0
18
125
1.45
0.73
1.2
2.0
—
1506.7
—
0
6
5
25
2.00
0.72
1.2
1.1
—
—
—
0
0
26
344
0.75
0.72
1.5
1.5
—
—
—
0
0
26
194
1.35
0.71
1.7
2.1
138.1
129.7
g/l
0.85
16
147
45
363
1.25
0.71
1.5
1.4
—
—
—
0
0
5
26
1.93
0.70
2.0
1.3
—
—
—
0
0
29
221
1.32
0.70
1.6
1.7
—
—
—
0
0
37
293
1.27
0.68
2.2
2.9
—
—
—
0
0
62
521
1.20
0.68
1.5
1.6
—
—
—
0
0
7
118
0.59
0.68
1.1
1.6
—
—
—
0
0
13
86
1.52
0.66
2.5
1.2
2.8
0.7
u/ml
—
6
42
37
295
1.26
0.65
1.5
1.6
0.9
0.1
iu/ml
0.47
11
49
10
62
1.62
0.65
1.1
1.2
—
—
—
0
0
16
112
1.43
0.63
1.4
1.4
186.3
339.1
pmol/l
2.09
11
92
34
270
1.27
0.63
3.1
3.9
28.4
42.6
mg/l
0.61
28
217
34
270
1.27
0.63
3.1
3.9
52.0
73.2
mg/l
0.39
28
217
29
226
1.29
0.62
1.5
1.7
—
—
—
0
0
9
139
0.64
0.60
1.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
51
427
1.20
0.60
8.8
3.7
24.5
24.2
mmol/l
0.33
42
385
11
72
1.53
0.59
1.5
1.5
43.7
58.5
pmol/l
—
5
20
12
81
1.49
0.57
2.6
2.5
—
—
—
0
0
23
176
1.31
0.56
1.4
1.6
—
—
—
0
0
59
505
1.18
0.55
1.2
1.1
—
—
—
0
0
55
468
1.18
0.55
8.8
10.0
23.9
24.5
mmol/l
0.52
50
440
24
187
1.29
0.53
1.4
1.4
—
—
—
0
0
24
187
1.29
0.53
1.4
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
9
63
1.43
0.52
1.1
1.2
—
—
—
0
0
9
63
1.43
0.52
1.1
1.2
—
—
—
0
0
22
172
1.28
0.48
1.6
1.5
103.8
113.1
u/ml
—
6
39
30
365
0.82
0.47
1.7
1.9
—
—
—
0
0
18
138
1.31
0.45
1.3
1.5
—
—
—
0
0
19
147
1.30
0.45
1.5
1.4
0.3
0.3
nmol/l
0.66
11
121
13
95
1.37
0.43
1.7
2.6
—
—
—
0
0
11
78
1.41
0.43
1.1
1.1
68.6
39.1
mg/l
0.43
11
64
5
31
1.62
0.43
1.0
1.3
—
—
—
0
0
16
122
1.32
0.42
1.3
1.6
—
—
—
0
0
24
194
1.24
0.42
2.1
3.6
25.9
25.5
mg/l
0.02
13
118
10
70
1.43
0.41
1.1
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
56
493
1.14
0.40
1.3
1.3
38.8
31.0
iu/l
0.88
49
421
0
18
0.00
0.40
0.0
2.1
—
0.6
—
0
13
31
260
1.20
0.39
2.2
1.9
7.4
5.3
iu/l
—
9
93
19
237
0.80
0.39
1.4
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
2.1
—
7.5
—
0
10
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
35
299
1.18
0.37
1.5
1.3
—
—
—
0
0
103
949
1.09
0.35
3.0
3.1
—
—
—
0
0
6
42
1.43
0.35
1.5
1.8
0.9
5.7
nmol/l
—
6
37
17
135
1.26
0.35
1.1
1.1
1.5
1.5
g/l
0.24
17
123
29
340
0.85
0.34
1.6
1.7
—
—
—
0
0
77
701
1.11
0.34
1.3
1.2
178.2
146.8
iu/ml
0.21
24
287
172
1623
1.07
0.33
3.1
2.8
0.7
0.7
ug/l
1.02
123
961
24
201
1.20
0.32
4.7
2.4
1.3
0.9
nmol/l
1.54
19
173
10
74
1.35
0.32
1.0
1.0
—
—
—
0
0
40
351
1.14
0.32
3.8
3.5
50.3
3719.6
u/ml
0.72
34
303
47
418
1.13
0.31
1.6
1.7
2.6
4.5
mg/l
0.66
34
296
7
53
1.32
0.31
1.0
1.0
—
—
—
0
0
7
54
1.30
0.30
1.7
1.6
—
—
—
0
0
7
55
1.27
0.30
1.1
2.1
—
—
—
0
0
57
516
1.11
0.29
1.2
1.4
—
—
—
0
0
29
251
1.16
0.28
1.7
1.3
533.7
494.7
mg/l
0.24
29
237
28
242
1.16
0.28
1.2
1.2
—
—
—
0
0
8
67
1.20
0.26
1.5
1.8
—
—
—
0
0
26
225
1.16
0.26
2.1
3.2
33.1
34.2
umol/l
0.08
21
192
79
733
1.08
0.26
3.2
3.6
1.2
1.2
mmol/l
0.08
72
632
12
96
1.25
0.24
1.0
1.1
—
—
—
0
0
10
126
0.79
0.24
1.4
1.5
—
—
—
0
0
10
126
0.79
0.24
1.4
1.5
—
—
—
0
0
10
126
0.79
0.24
1.4
1.5
—
—
—
0
0
26
229
1.14
0.21
1.8
1.2
4.1
3.8
mmol/l
0.47
26
215
10
124
0.80
0.21
1.4
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
0.1
—
0
6
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
7.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
24
211
1.14
0.20
1.3
1.4
—
—
—
0
0
10
123
0.81
0.20
1.4
1.5
—
—
—
0
0
10
123
0.81
0.20
1.4
1.5
—
—
—
0
0
6
48
1.25
0.20
1.3
1.7
—
—
—
0
0
236
2289
1.04
0.19
2.6
2.3
—
—
—
0
0
16
184
0.87
0.17
4.6
4.0
57.9
58.9
%
0.15
16
184
93
885
1.06
0.17
2.6
2.2
0.2
0.2
g/l
0.28
86
837
110
1052
1.05
0.17
2.1
1.9
—
—
—
0
0
12
101
1.19
0.16
1.1
1.7
—
—
—
0
0
29
264
1.10
0.15
1.4
1.4
15.1
9.5
u/l
0.62
23
215
6
78
0.77
0.15
2.2
1.4
—
—
—
0
0
9
80
1.13
0.15
1.7
1.7
—
—
—
0
0
18
160
1.13
0.14
1.3
1.5
—
—
—
0
0
16
179
0.89
0.12
4.2
3.7
4.0
4.2
e9/l
0.18
16
179
18
199
0.90
0.11
3.0
3.4
8.4
8.2
kpa
0.19
18
183
5
46
1.09
0.09
1.8
1.7
—
—
—
0
0
5
47
1.06
0.09
2.0
2.0
—
—
—
0
0
5
47
1.06
0.09
1.8
1.7
—
—
—
0
0
131
1343
0.97
0.09
1.7
1.8
1.5
1.5
%
0.15
115
1189
5
48
1.04
0.09
1.6
2.9
—
—
—
0
0
6
54
1.11
0.09
1.2
1.1
—
—
—
0
0
7
67
1.05
0.08
1.4
1.9
—
—
—
0
0
22
205
1.07
0.08
5.1
1.7
—
—
—
0
0
96
935
1.03
0.07
2.1
1.8
—
—
—
0
0
8
74
1.08
0.07
1.6
1.1
—
—
—
0
0
57
550
1.04
0.07
2.9
4.1
2.1
1.9
mmol/l
0.18
41
419
8
77
1.04
0.07
1.1
1.0
287.3
283.7
mg/l
—
8
67
7
84
0.83
0.07
1.0
1.0
—
—
—
0
0
9
84
1.07
0.07
1.1
1.6
1.0
1.0
g/l
—
9
84
9
101
0.89
0.06
1.4
1.2
—
—
—
0
0
33
345
0.96
0.06
1.5
1.5
—
—
—
0
0
16
172
0.93
0.06
2.2
2.5
17.2
16.2
%
—
9
96
14
130
1.08
0.04
1.1
1.3
0.6
0.6
nmol/l
0.40
14
123
13
137
0.95
0.01
2.0
1.7
—
—
—
0
0
21
203
1.04
0.01
1.4
1.2
—
—
—
0
0
22
213
1.03
0.01
1.9
1.6
—
—
—
0
0
12
114
1.05
0.00
1.0
1.1
—
—
—
0
0
52
524
0.99
0.00
2.7
3.0
19.7
62.6
u/ml
2.99
52
505
94
937
1.00
0.00
4.7
4.3
6.8
27.5
ug/l
1.37
72
758
11
115
0.96
0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
5.0
—
—
—
0
0
6
63
0.95
0.00
1.8
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
0.00
1.3
1.2
—
—
—
0
0
8
88
0.91
0.00
1.0
1.6
—
—
—
0
0
8
84
0.95
0.00
3.4
3.9
—
—
—
0
0
8
88
0.91
0.00
1.0
1.6
—
—
—
0
0
8
88
0.91
0.00
1.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
6
63
0.95
0.00
1.8
1.3
—
—
—
0
0
5
50
1.00
0.00
1.2
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
5.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
0.00
1.2
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_CORNEALNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CORNEALNAS | 1.154 [0.99, 1.34] | 0.064 |
| Birth year | 0.992 [0.98, 1.0] | 0.064 |
During the follow-up period (1.1.1998 — 31.12.2019), 407 out of 3842 females with H7_CORNEALNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CORNEALNAS | 1.221 [1.03, 1.44] | 0.019 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 340 out of 3257 males with H7_CORNEALNAS died.
Mortality risk
Mortality risk for people of age
years, who have H7_CORNEALNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.096% | 0.159% |
| 5 | 0.622% | 1.398% |
| 10 | 1.589% | 3.359% |
| 15 | 2.881% | 6.346% |
| 20 | 4.996% | 10.9% |
Relationships between endpoints
↥Index endpoint: H7_CORNEALNAS – Other and unspecified corneal deformities and disorders
GWS hits: 5
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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