corneal disease: A non-neoplastic or neoplastic disorder that affects the cornea. Representative examples include keratitis, bullous keratopathy, and squamous cell carcinoma.
Other and unspecified corneal deformities and disorders
DOID EFO Endpoint Browser PheWeb
H7_CORNEALNAS
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1261 |
4. Check minimum number of eventsNone |
1261 |
5. Include endpointsNone |
1261 |
6. Filter based on genotype QC (FinnGen only) |
1211 |
Control definitions (FinnGen only)
- Control exclude
- H7_SCLERACORNEA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF6
Similar endpoints
↥List of similar endpoints to
Other and unspecified corneal deformities and disorders
based on the number of shared cases.
Similar with more cases:
- Other disorders of cornea
- Disorders of sclera, cornea, iris and ciliary body
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8787 | 4685 | 4066 |
| Only index persons | 8268 | 4439 | 3829 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.13 | 0.11 |
| Only index persons | 0.16 | 0.16 | 0.15 |
| Median age at first event (years) | |||
| Whole population | 46.79 | 50.05 | 42.97 |
| Only index persons | 46.07 | 49.15 | 42.49 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1211 | 726 | 485 |
| Unadjusted period prevalence (%) | 0.24 | 0.26 | 0.22 |
| Median age at first event (years) | 50.55 | 50.34 | 50.85 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1261
- Matched controls
- 12610
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H16.0
ICD-10 Finland
Corneal ulcer
86.4
307.7
426
74
H18.8
ICD-10 Finland
Other specified disorders of cornea
13599.9
307.7
926
*
CG2T4
NOMESCO Finland
Topography assessment of cornea
108.5
247.0
127
13
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
6.8
223.8
928
3667
XCW99
NOMESCO Finland
Other investigative procedure of eye
7.1
183.1
332
608
S01AD03
ATC
aciclovir; ophthalmic
13.3
168.3
168
144
H18.9
ICD-10 Finland
Disorder of cornea, unspecified
+∞
166.4
156
*
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
809.8
149.4
144
*
H16.9
ICD-10 Finland
Keratitis, unspecified
323.5
143.7
143
5
H18.7
ICD-10 Finland
Other corneal deformities
1434.5
134.9
129
*
CGD10
NOMESCO Finland
Laser keratoplasty for error of refraction
56.9
132.5
75
14
Z94.7
ICD-10 Finland
Corneal transplant status
+∞
115.4
109
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
141.8
110.1
116
9
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
132.4
102.8
109
9
Z96.1
ICD-10 Finland
Presence of intraocular lens
4.5
98.0
291
795
H18.6
ICD-10 Finland
Keratoconus
1001.7
96.3
93
*
H04.10
ICD-10 Finland
Dry eye syndrome
4.5
95.0
273
726
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
3.2
87.8
585
2690
S01ED01
ATC
timolol; ophthalmic
8.6
79.0
105
132
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
26.8
78.1
54
21
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.1
76.9
244
692
H18.4
ICD-10 Finland
Corneal degeneration
207.6
76.1
78
*
3718X
ICD-9 Finland
Corneal opacity and other disorders of cornea, Other corneal disorders
+∞
74.7
71
*
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
+∞
72.6
69
*
S05.0
ICD-10 Finland
Injury of conjunctiva and corneal abrasion without mention of foreign body
9.7
71.1
85
93
H57.1
ICD-10 Finland
Ocular pain
7.2
68.8
107
161
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
4.1
68.5
211
583
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
235.6
65.9
67
*
XCK10
NOMESCO Finland
Photography of fundus of eye
4.0
64.1
203
571
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.1
64.0
333
1290
S01AA01
ATC
chloramphenicol; ophthalmic
5.4
61.1
129
262
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
311.4
58.8
59
*
S01EA05
ATC
brimonidine; ophthalmic
8.9
58.0
74
88
TCG10
NOMESCO Finland
Removal of sutures from cornea
108.6
57.4
62
6
WX140
NOMESCO Finland
Parabulbar anesthesy
5.5
56.4
115
226
S01ED51
ATC
timolol, combinations; ophthalmic
4.3
54.2
150
380
CG2S4
NOMESCO Finland
Photography of cornea
119.3
53.3
57
5
3604
FHL
Penetration of the cornea
+∞
50.3
48
*
S01BA07
ATC
fluorometholone; ophthalmic
9.4
49.3
60
67
H18.1
ICD-10 Finland
Bullous keratopathy
496.3
48.7
48
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.7
48.4
166
490
S01BC03
ATC
diclofenac; ophthalmic
7.9
47.0
66
88
S01XA18
ATC
ciclosporin; ophthalmic
16.3
44.5
38
24
S01BA04
ATC
prednisolone; ophthalmic
9.5
44.2
53
58
H17.8
ICD-10 Finland
Other corneal scars and opacities
442.3
43.5
43
*
H16.2
ICD-10 Finland
Keratoconjunctivitis
222.4
42.1
43
*
S01BA01
ATC
dexamethasone; ophthalmic
5.6
41.0
81
154
H16.8
ICD-10 Finland
Other keratitis
206.4
39.0
40
*
S01EC01
ATC
acetazolamide; systemic
7.7
38.8
55
74
S01EA03
ATC
apraclonidine; ophthalmic
13.7
38.4
36
27
H17.1
ICD-10 Finland
Other central corneal opacity
+∞
37.7
36
*
H25.1
ICD-10 Finland
Senile nuclear cataract
2.4
37.5
355
1801
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
14.5
37.5
34
24
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.2
35.9
401
2175
H20.1
ICD-10 Finland
Chronic iridocyclitis
+∞
35.6
34
*
CGG11
NOMESCO Finland
Corneal cross-linking
+∞
34.5
33
*
3619
FHL
Other operations in this group, such as corneal refractive surgery
+∞
34.5
33
*
ZXA10
NOMESCO Finland
Bilateral
2.4
34.1
277
1307
CJB10
NOMESCO Finland
Laser discission of secondary cataract
3.4
34.0
132
420
H52.2
ICD-10 Finland
Astigmatism
6.6
33.1
54
85
F01
ICPC
Eye pain
5.4
32.6
66
128
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
+∞
32.4
31
*
H3603, E103,
ICD-10 Finland
10.9
32.3
35
33
XCK00
NOMESCO Finland
Perimetry
3.7
32.3
109
316
CGE10
NOMESCO Finland
Keratectomy
+∞
31.4
30
*
3716A
ICD-9 Finland
Corneal opacity and other disorders of cornea, Keratoconus
+∞
31.4
30
*
ZXA05
NOMESCO Finland
Left side
2.2
30.9
357
1944
H26.4
ICD-10 Finland
After-cataract
3.0
30.9
149
539
114
Kela drug reimbursment
Glaucoma
3.2
30.8
135
462
XCH00
NOMESCO Finland
Eye pressure measurement
4.1
30.4
88
229
S01EE01
ATC
latanoprost; ophthalmic
3.6
28.8
102
305
H18.2
ICD-10 Finland
Other corneal oedema
+∞
28.2
27
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
5.6
27.6
53
98
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.3
27.2
109
353
A10AA01, ,
ATC
4.8
26.8
62
135
L04AA01
ATC
[U] ciclosporin
8.7
26.7
34
40
H26.2
ICD-10 Finland
Complicated cataract
8.1
25.2
34
43
A10AB01
ATC
insulin (human); parenteral
4.0
25.2
73
190
CGG31
NOMESCO Finland
Posterior corneal lamellar transplantation
+∞
25.1
24
*
H40.0
ICD-10 Finland
Glaucoma suspect
2.9
24.8
126
467
CG2Z4
NOMESCO Finland
Specialised imaging of cornea
255.0
24.8
25
*
Z3231
NOMESCO Finland
Registered nurse
2.0
24.5
363
2139
ZXA00
NOMESCO Finland
Right side
2.0
24.0
360
2127
S01EX03, ,
ATC
6.0
22.4
40
69
A10AA02, ,
ATC
4.0
22.2
64
166
H26.02
ICD-10 Finland
Presenil cataract
4.5
22.1
54
123
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
+∞
21.9
21
*
S01EC04
ATC
brinzolamide; ophthalmic
3.9
21.9
67
181
H19.1
ICD-10 Finland
Herpesviral keratitis and keratoconjunctivitis
117.1
21.6
23
*
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
8.9
21.6
27
31
S01FA01
ATC
atropine; ophthalmic
31.8
21.5
28
9
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.8
20.6
105
390
WX002
NOMESCO Finland
Sedation and analgesia
2.0
19.6
261
1469
F29
ICPC
Eye symptom/complaint other
2.4
19.4
138
604
S01AX11
ATC
[U] ofloxacin
3.8
19.3
60
164
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
7.3
19.1
28
39
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.4
19.1
71
219
H43.1
ICD-10 Finland
Vitreous haemorrhage
4.9
19.0
42
88
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
4.1
19.0
53
134
H04AA01
ATC
glucagon; nasal, parenteral
4.8
18.8
43
93
H16.1
ICD-10 Finland
Other superficial keratitis without conjunctivitis
71.0
18.7
21
*
S01GX01
ATC
cromoglicic acid; ophthalmic
1.9
17.8
275
1620
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
2.7
17.5
94
359
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
29.2
17.4
23
8
9881
FHL
Bandage replacement, suture or spike removal, or the like in an operating room or anesthesia
50.7
17.0
20
*
S01BC05
ATC
ketorolac; ophthalmic
3.5
16.7
57
166
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
5.9
16.7
30
52
TCG30
NOMESCO Finland
Imaging of anterior and posterior part of cornea
172.2
16.5
17
*
S01FA04
ATC
cyclopentolate; ophthalmic
13.0
16.2
28
22
T89
ICPC
Diabetes insulin dependent
3.1
15.9
67
223
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
3.1
15.9
67
223
A10AB04
ATC
insulin lispro; parenteral
3.4
15.9
58
177
S01EC03
ATC
dorzolamide; ophthalmic
6.5
15.9
26
41
ZXD20
NOMESCO Finland
Day surgery
2.0
15.8
180
953
127
Kela drug reimbursment
Transplant complication
5.2
15.6
32
63
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
4.1
15.5
42
104
CGF10
NOMESCO Finland
Suture of laceration of cornea
161.9
15.5
16
*
S01EE05
ATC
tafluprost; ophthalmic
3.4
15.5
57
175
H52.1
ICD-10 Finland
Myopia
3.3
15.2
58
182
H15.1
ICD-10 Finland
Episcleritis
18.0
15.2
23
13
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
15.1
466
3319
CD2S4
NOMESCO Finland
Photography of eye
12.6
14.9
26
21
S01AA12
ATC
tobramycin; ophthalmic
32.1
14.8
19
6
H16.4
ICD-10 Finland
Corneal neovascularization
+∞
14.6
14
*
H18.0
ICD-10 Finland
Corneal pigmentations and deposits
+∞
14.6
14
*
3710A
ICD-9 Finland
Corneal opacity and other disorders of cornea, Corneal scars and opacities
+∞
14.6
14
*
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.9
14.5
43
114
T86.8
ICD-10 Finland
Failure and rejection of other transplanted organs and tissues
151.7
14.5
15
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.0
14.3
168
898
S01KA02
ATC
hypromellose; ophthalmic
4.8
14.3
32
68
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
3.0
14.1
63
217
H33.0
ICD-10 Finland
Retinal detachment with retinal break
3.6
14.0
47
136
37103
ICD-8 Finland
Corneal opacity, Keratoconus
+∞
13.6
13
*
CGW99
NOMESCO Finland
Other operation on cornea or sclera
+∞
13.6
13
*
CGD99
NOMESCO Finland
Other operation for error of refraction
141.5
13.5
14
*
CFD10
NOMESCO Finland
Repair of conjunctiva
40.5
13.2
16
*
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
3.8
12.8
38
101
H16.3
ICD-10 Finland
Interstitial and deep keratitis
+∞
12.5
12
*
CGF35
NOMESCO Finland
Repair of cornea using graft
+∞
12.5
12
*
S01FA02
ATC
scopolamine; ophthalmic
14.5
12.3
20
14
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
6.1
12.1
21
35
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
4.1
11.9
32
79
E10
ICD-10 Finland
Type 1 diabetes mellitus
3.9
11.9
34
88
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
5.2
11.8
24
47
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
11.6
287
1913
3700A
ICD-9 Finland
Keratitis, Corneal ulcer
+∞
11.5
11
*
H18.3
ICD-10 Finland
Changes in corneal membranes
+∞
11.5
11
*
H15.0
ICD-10 Finland
Scleritis
+∞
11.5
11
*
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
+∞
11.5
11
*
H36.00
ICD-10 Finland
Diabetic background retinopathy
4.9
11.5
25
52
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
8.4
11.3
24
29
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
8.4
11.3
24
29
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
17.2
11.2
17
10
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
25.3
11.1
15
6
H02AB06
ATC
prednisolone; systemic
1.5
11.1
559
4365
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
3.1
11.1
45
147
D07AC01
ATC
betamethasone; topical
1.5
11.1
421
3098
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
43.7
10.9
13
*
H19.2*B02.3
ICD-10 Finland
Keratitis and keratoconjunctivitis (interstitial) in zoster
43.7
10.9
13
*
A10AE04
ATC
insulin glargine; parenteral
2.0
10.6
121
638
H53.1
ICD-10 Finland
Subjective visual disturbances
2.2
10.6
90
424
H54.1
ICD-10 Finland
Severe visual impairment, binocular
110.9
10.4
11
*
ZZL00
NOMESCO Finland
Free graft of amniotic membrane
110.9
10.4
11
*
H19.8*E85.80
ICD-10 Finland
Reticular keratitis in Meretoja's patients
+∞
10.4
10
*
E85.80
ICD-10 Finland
Meretoja sick
+∞
10.4
10
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
10.4
540
4228
A10AC01
ATC
insulin (human); parenteral
2.1
10.3
99
490
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.4
10.3
71
306
UJF32
NOMESCO Finland
Coloscopy
1.6
10.3
295
2031
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
10.0
509
3958
A10AB05
ATC
insulin aspart; parenteral
2.1
10.0
94
462
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
40.4
10.0
12
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
9.8
214
1374
H11.0
ICD-10 Finland
Pterygium
7.9
9.6
21
27
S01EE03
ATC
bimatoprost; ophthalmic
3.3
9.6
35
107
ZXE00
NOMESCO Finland
One hour or less
1.5
9.5
446
3403
A10AE06
ATC
insulin degludec; parenteral
2.7
9.5
52
201
CBH25
NOMESCO Finland
Tarsorrhaphy
100.8
9.4
10
*
37100
ICD-8 Finland
Corneal opacity, Cicatrix (nubecula, macula, leucoma) cornea
+∞
9.4
9
*
CGE16
NOMESCO Finland
Destruction of lesion of cornea
+∞
9.4
9
*
H21.0
ICD-10 Finland
Hyphaema
+∞
9.4
9
*
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
5.2
9.4
19
37
H27.0
ICD-10 Finland
Aphakia
13.8
9.2
15
11
J01DB01
ATC
cefalexin; oral
1.6
9.2
1000
8961
J05AB11
ATC
valaciclovir; oral
1.7
9.2
172
1061
CKC12
NOMESCO Finland
Photocoagulation of retina
2.6
9.1
53
211
J01MA02
ATC
ciprofloxacin; systemic
1.5
9.1
436
3334
N03AX16
ATC
[U] pregabalin
1.6
9.1
270
1867
S01XA02
ATC
retinol; ophthalmic
11.6
9.1
16
14
S01EB01
ATC
pilocarpine; ophthalmic
9.1
9.0
18
20
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
12.6
8.9
15
12
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.1
8.8
24
60
103
Kela drug reimbursment
Diabetes, insulin-treated
1.5
8.5
293
2091
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
8.5
86
436
3606
FHL
Keratophakic corneal surgery
+∞
8.3
8
*
37108
ICD-8 Finland
Corneal opacity, Alia definita
+∞
8.3
8
*
T85.3
ICD-10 Finland
Mechanical complication of other ocular prosthetic devices, implants and grafts
+∞
8.3
8
*
CBH30
NOMESCO Finland
Tarsorraphy
+∞
8.3
8
*
H17.0
ICD-10 Finland
Adherent leukoma
+∞
8.3
8
*
36400
ICD-8 Finland
Iritis, Iridocyclitis acuta
+∞
8.3
8
*
L04AD01
ATC
ciclosporin; systemic
3.6
8.3
27
77
H25.0
ICD-10 Finland
Senile incipient cataract
2.2
8.2
72
345
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
8.2
405
3104
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
8.2
406
3115
E000001, ,
ATC
1.6
8.2
225
1528
D07AB08
ATC
desonide; topical
1.8
8.1
126
735
R51.80
ICD-10 Finland
Headache
1.6
8.1
182
1177
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
3.5
8.0
27
79
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.2
7.9
31
100
H3601, E103,
ICD-10 Finland
7.0
7.8
18
26
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
7.8
325
2409
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.6
7.7
42
162
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
6.4
7.7
19
30
H54.0
ICD-10 Finland
Blindness, binocular
45.3
7.7
9
*
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
45.3
7.7
9
*
A07AA02
ATC
nystatin; oral
2.1
7.6
70
342
J01AA02
ATC
doxycycline; systemic
1.4
7.6
929
8307
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
25.2
7.6
10
*
H25.8
ICD-10 Finland
Other senile cataract
1.8
7.6
105
592
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
10.1
7.5
14
14
J01FF01
ATC
clindamycin; systemic
1.5
7.4
310
2294
H20.8
ICD-10 Finland
Other iridocyclitis
80.6
7.4
8
*
S01EE04
ATC
travoprost; ophthalmic
3.5
7.4
25
73
A10AE05
ATC
insulin detemir; parenteral
2.1
7.4
65
312
Z2221
NOMESCO Finland
Medical doctor
1.5
7.4
306
2261
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.7
7.4
150
944
36399
ICD-8 Finland
Keratitis, Without mention of ulcer
+∞
7.3
7
*
CGD40
NOMESCO Finland
Implantation of intracorneal ring segments
+∞
7.3
7
*
3642
FHL
Anterior vitrectomy
+∞
7.3
7
*
3714A
ICD-9 Finland
Corneal opacity and other disorders of cornea, Corneal degenerations
+∞
7.3
7
*
3719X
ICD-9 Finland
Corneal opacity and other disorders of cornea, Unspecified corneal disorder
+∞
7.3
7
*
3719
FHL
Other measure in this category
+∞
7.3
7
*
M79.6
ICD-10 Finland
Pain in limb
1.4
7.2
474
3804
H01.0
ICD-10 Finland
Blepharitis
2.0
7.2
78
406
A10AD01
ATC
insulin (human); parenteral
3.5
7.1
24
70
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
8.0
7.1
15
19
H10.4
ICD-10 Finland
Chronic conjunctivitis
4.1
7.1
19
47
S01AX12
ATC
[U] norfloxacin
8.8
7.1
14
16
H40.9
ICD-10 Finland
Glaucoma, unspecified
3.3
7.0
25
76
L01BA01
ATC
methotrexate; systemic
2.5
6.9
42
172
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
13.9
6.9
11
8
S01EA02
ATC
dipivefrine; ophthalmic
13.9
6.9
11
8
J01FA10
ATC
azithromycin; systemic
1.4
6.9
665
5668
S01GX09
ATC
olopatadine; ophthalmic
2.6
6.8
37
143
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
6.8
150
964
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
6.1
6.8
17
28
CHB15
NOMESCO Finland
Puncture of anterior chamber of eye with replacement of aqueous
40.3
6.8
8
*
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
40.3
6.8
8
*
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
7.2
6.7
15
21
H3600, E103,
ICD-10 Finland
4.0
6.6
18
45
R4110
NOMESCO Finland
Physiotherapy
1.4
6.6
302
2267
E0000UV, ,
ATC
1.4
6.6
459
3705
D06BX01
ATC
metronidazole; topical
1.7
6.5
125
774
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.8
6.5
94
537
F02
ICPC
Red eye
2.3
6.5
47
209
L17
ICPC
Foot/toe symptom/complaint
1.4
6.5
309
2339
J02AC01
ATC
fluconazole; systemic
1.4
6.4
448
3613
S05.2
ICD-10 Finland
Ocular laceration and rupture with prolapse or loss of intraocular tissue
70.2
6.4
7
*
H54.4
ICD-10 Finland
Blindness, monocular
14.4
6.4
10
7
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.9
6.4
82
452
R42
ICD-10 Finland
Dizziness and giddiness
1.5
6.3
238
1721
CHC05
NOMESCO Finland
Iridotomy
3.6
6.3
20
56
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
6.3
281
2098
H27.1
ICD-10 Finland
Dislocation of lens
11.1
6.3
11
10
H3602, E103,
ICD-10 Finland
18.1
6.3
9
5
37403
ICD-8 Finland
Cataract, Complicata
+∞
6.3
6
*
36402
ICD-8 Finland
Iritis, Iridocyclitis, uveitis chronica
+∞
6.3
6
*
CGG30
NOMESCO Finland
Anterior lamellar transplantation of cornea
+∞
6.3
6
*
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
6.3
6
*
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
2.8
6.2
30
109
3643
FHL
Vitrectomy through pars Plana
26.8
6.2
8
*
Z97.0
ICD-10 Finland
Presence of artificial eye
26.8
6.2
8
*
H44.0
ICD-10 Finland
Purulent endophthalmitis
26.8
6.2
8
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.9
6.2
28
98
S01AA02
ATC
chlortetracycline; ophthalmic
7.1
6.2
14
20
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
6.2
88
501
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
3.5
6.2
20
57
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
6.3
6.2
15
24
M03BX02
ATC
tizanidine; oral
1.3
6.1
735
6424
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
12.6
6.1
10
8
CGE55
NOMESCO Finland
Excision of pterygium with transplanation of conjunctiva
12.6
6.1
10
8
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.8
6.0
93
542
N02AX02
ATC
tramadol; systemic, rectal
1.4
6.0
475
3895
W22
ICD-10 Finland
Striking against or struck by other object(s)
1.9
6.0
74
402
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
41
88
4.78
18.07
1.4
1.3
—
—
—
0
0
24
46
5.30
12.04
1.5
1.2
—
—
—
0
0
1135
10378
1.94
11.31
16.1
13.2
21.82
23.05
mg/l
0.65
902
8165
907
7835
1.56
11.10
7.9
7.4
77.07
77.79
u/l
0.19
867
7410
1156
10690
1.98
10.31
18.7
15.1
3.97
3.96
mmol/l
0.19
1137
10398
388
2859
1.52
9.92
3.6
3.3
1149.29
389.26
mg/l
1.13
271
1809
711
5913
1.46
9.82
9.5
9.0
4.10
4.06
e9/l
0.19
634
5207
870
7532
1.50
9.77
4.4
3.9
12.56
11.66
mm/h
0.93
813
7001
404
3016
1.50
9.65
4.3
3.8
8.31
8.06
mg/mmol
0.03
272
1884
1150
10655
1.90
9.61
18.6
15.0
139.72
139.67
mmol/l
0.29
1129
10381
397
2962
1.50
9.48
2.2
2.1
136.30
237.74
u/l
2.29
378
2805
409
3085
1.48
9.20
3.5
3.2
8.05
7.61
mmol/l
1.00
350
2626
696
5848
1.42
8.58
5.6
4.7
6.84
6.67
mmol/l
1.27
648
5490
526
4220
1.42
8.32
5.7
4.8
35.94
35.77
g/l
0.31
497
3945
761
6541
1.41
7.97
4.8
4.2
1239.69
2481.22
e6/l
0.53
13
93
596
4931
1.40
7.70
7.0
5.8
27.97
28.14
%
0.13
566
4645
588
4865
1.39
7.54
7.1
5.6
56.99
57.04
%
0.03
557
4578
1179
11157
1.87
7.11
11.8
9.9
26.33
26.85
u/l
0.53
1156
10817
591
4938
1.37
6.94
3.9
3.5
0.00
0.00
estimate
0.50
95
970
76
397
1.97
6.91
1.2
1.2
1.37
1.77
u/ml
—
7
29
1040
9569
1.50
6.76
5.4
4.7
1.89
2.01
mu/l
0.46
969
8834
993
9055
1.45
6.76
20.1
15.8
14.49
14.78
%
1.06
978
8883
514
4216
1.37
6.71
2.7
2.2
78.54
76.06
nmol/l
1.18
468
3814
485
3955
1.37
6.51
2.1
1.9
96.18
96.46
pmol/l
0.04
257
2068
588
4943
1.36
6.49
5.3
4.7
0.00
0.00
estimate
0.50
87
918
237
1705
1.48
6.48
1.6
1.7
1195.13
1189.49
nmol/l
0.03
182
1288
593
4994
1.35
6.46
3.9
3.5
0.00
0.01
estimate
0.80
78
881
400
3167
1.39
6.43
3.1
2.6
54.77
58.35
u/l
0.86
370
2942
1037
9581
1.46
6.16
6.8
5.4
41.31
39.47
mmol/mol
6.33
985
8941
428
3445
1.37
6.16
3.4
3.3
37.31
32.21
u/l
0.27
415
3275
119
750
1.65
5.83
4.1
3.8
84.98
84.77
ng/l
0.01
102
664
103
625
1.71
5.82
3.6
3.3
4.49
4.55
pmol/l
0.15
88
557
775
6866
1.33
5.67
3.1
3.0
—
—
—
0
0
530
4464
1.32
5.47
12.9
13.4
1.18
1.22
inr
0.57
142
1305
884
8018
1.34
5.32
4.6
4.0
14.66
14.69
pmol/l
0.13
810
7361
247
1858
1.41
5.25
4.8
3.6
196.29
415.08
ng/l
1.17
194
1392
64
358
1.83
4.81
2.0
2.2
—
—
—
0
0
332
2653
1.34
4.81
3.8
3.0
0.24
0.46
e6/l
2.60
277
2019
567
4880
1.29
4.79
8.2
6.6
1.22
1.21
mmol/l
0.20
493
4169
241
1838
1.38
4.69
1.4
1.3
129.28
30.10
iu/ml
0.41
90
594
163
1161
1.46
4.64
3.5
2.7
7.95
8.10
umol/l
0.03
141
1011
156
1102
1.47
4.63
7.4
7.7
1.12
1.25
mmol/l
0.14
122
888
112
737
1.57
4.63
3.3
2.8
187.84
189.41
ng/l
0.01
105
669
406
3362
1.31
4.54
3.3
3.5
2.35
2.35
mmol/l
0.05
359
2989
96
614
1.61
4.48
7.8
7.3
24.87
24.63
mmol/l
0.29
90
587
299
2378
1.34
4.43
2.6
2.1
2.84
3.02
mg/l
0.69
268
2042
329
2667
1.32
4.25
2.9
3.0
1199.22
1139.10
ng/l
0.11
296
2240
354
2901
1.31
4.22
3.9
3.1
74.13
86.10
e6/l
0.10
296
2245
511
4390
1.28
4.22
3.3
2.7
103.41
121.83
ug/l
1.65
480
4084
792
7177
1.28
4.21
3.2
3.1
44.05
48.31
u/l
1.07
755
6743
58
329
1.80
4.20
1.9
2.3
10.34
10.41
g/l
0.04
53
295
173
1272
1.42
4.16
6.6
5.6
1.05
1.03
mmol/l
0.49
155
1172
212
1616
1.37
4.12
3.2
2.6
0.92
1.16
e6/l
0.64
141
916
65
385
1.73
4.08
7.4
5.5
1.73
1.58
%
0.54
60
361
331
2702
1.31
4.04
1.8
1.6
1.38
1.41
mmol/l
0.19
288
2296
1205
11668
1.74
4.04
24.2
19.5
40.13
40.37
%
0.65
1122
10953
513
4435
1.26
3.95
7.1
5.9
1.21
1.21
mmol/l
0.01
471
4052
598
5265
1.26
3.94
6.4
6.3
10.67
11.36
umol/l
0.83
572
5007
282
2261
1.32
3.91
1.5
1.5
23.12
21.08
nmol/l
0.87
245
1941
149
1080
1.43
3.88
1.9
1.7
—
—
—
0
0
1096
10421
1.40
3.87
5.1
4.3
4.66
4.74
mmol/l
1.84
1040
9746
1205
11680
1.71
3.85
24.2
19.4
6.76
6.66
e9/l
0.48
1180
11376
27
120
2.28
3.82
1.0
1.1
—
—
—
0
0
1204
11673
1.70
3.78
24.2
19.4
253.77
253.04
e9/l
0.14
1181
11398
1111
10596
1.41
3.77
5.5
4.7
2.75
2.82
mmol/l
1.84
1050
9850
286
2316
1.30
3.67
1.4
1.2
3.02
1.54
u/ml
0.48
88
650
1204
11682
1.68
3.64
24.2
19.4
4.49
4.52
e12/l
1.23
1175
11380
253
2019
1.32
3.61
1.6
1.4
2.45
2.42
g/l
0.09
164
1272
150
1103
1.41
3.61
7.7
7.7
12.10
12.25
kpa
0.14
141
1060
150
1103
1.41
3.61
7.7
7.7
5.11
5.12
kpa
0.09
140
1058
317
2609
1.29
3.59
2.6
2.6
8321.92
5420.19
umol/l
0.39
286
2305
1204
11686
1.67
3.58
24.3
19.5
135.23
136.14
g/l
1.40
1191
11527
16
57
2.83
3.53
1.2
1.2
—
—
—
0
0
1089
10375
1.36
3.52
4.9
4.2
1.44
1.47
mmol/l
1.48
1035
9653
195
1505
1.35
3.49
3.5
2.8
3.72
2.87
e6/l
0.24
124
811
109
760
1.48
3.49
2.3
2.9
67.43
67.13
g/l
0.16
103
691
440
3782
1.25
3.45
3.6
3.4
45.87
50.18
ng/l
0.13
301
2513
252
2022
1.31
3.45
3.0
2.5
4.32
6.18
e6/l
1.98
237
1837
147
1087
1.40
3.43
1.9
1.8
—
—
—
0
0
222
1752
1.32
3.42
1.3
1.3
10.22
12.36
u/ml
0.15
80
684
286
2338
1.29
3.40
1.7
1.7
1.33
1.09
mg/l
0.30
217
1773
50
292
1.74
3.34
1.5
1.3
—
—
—
0
0
223
1769
1.32
3.31
2.9
3.0
2.45
2.45
mmol/l
0.27
198
1564
204
1599
1.33
3.30
4.1
3.3
0.82
0.82
mmol/l
0.16
193
1507
182
1403
1.35
3.29
2.6
2.4
2.34
2.36
g/l
0.19
172
1304
13
43
3.04
3.25
1.5
2.9
749.08
785.37
u/ml
0.05
13
43
269
2201
1.28
3.16
4.4
3.8
1.02
1.02
kg/l
0.55
33
315
113
816
1.42
3.04
3.7
2.5
58.76
66.73
ml/min/173m2
1.49
50
328
47
281
1.70
2.93
1.3
1.1
—
—
—
0
0
135
1012
1.37
2.92
3.7
2.7
1.83
1.80
%
0.11
118
909
115
839
1.41
2.92
8.8
7.6
9.05
8.93
mmol/l
0.07
107
800
225
1819
1.29
2.90
1.7
1.5
—
—
—
0
0
66
434
1.55
2.83
3.3
3.1
25.06
25.38
mmol/l
0.29
60
421
1050
10025
1.28
2.78
4.5
3.9
1.33
1.31
mmol/l
0.27
987
9267
192
1531
1.30
2.75
2.7
2.4
13.84
13.35
umol/l
0.41
181
1421
43
258
1.69
2.67
1.9
1.7
—
—
—
0
0
439
3858
1.21
2.65
4.1
3.6
—
—
—
0
0
95
693
1.40
2.45
1.7
1.3
276.99
180.54
u/ml
0.61
89
635
249
2079
1.25
2.45
1.7
1.7
452.98
35054926.27
pmol/l
2.16
217
1743
120
914
1.35
2.38
3.3
2.5
31.38
41.82
u/l
1.14
107
778
93
682
1.39
2.34
1.6
1.6
—
—
—
0
0
51
332
1.56
2.33
1.9
2.2
414.86
423.92
ug/l
0.02
46
310
297
2554
1.21
2.20
4.3
3.8
92.03
92.25
%
0.06
290
2486
132
1033
1.31
2.19
4.6
4.2
327.52
249.05
u/l
0.75
126
977
82
596
1.40
2.19
1.5
1.4
—
—
—
0
0
64
446
1.46
2.15
1.9
2.1
39.91
39.40
u/l
0.07
58
391
50
331
1.53
2.14
1.9
1.7
—
—
—
0
0
34
206
1.67
2.09
5.5
5.6
1493.67
326.17
iu/ml
—
6
29
112
863
1.33
2.08
5.0
3.5
2.14
1.97
mmol/l
0.24
95
722
1030
9892
1.23
2.08
14.1
12.0
82.27
83.03
ml/min/173m2
0.51
880
8161
25
139
1.81
2.06
1.0
1.1
10.76
4.13
u/ml
0.79
13
54
161
1308
1.26
2.01
2.8
2.4
25.17
23.11
%
1.04
139
1112
57
394
1.47
2.01
1.5
1.9
1.69
1.48
g/l
0.93
47
344
47
312
1.53
2.00
1.3
1.3
310.05
220.54
miu/ml
0.69
14
151
188
1558
1.24
1.98
1.9
1.8
—
—
—
0
0
154
1247
1.27
1.98
2.2
2.3
110.04
124.00
ug/g
0.26
120
997
20
105
1.92
1.96
1.1
1.7
—
—
—
0
0
26
149
1.76
1.95
1.0
1.0
4.32
2.29
u/ml
0.47
15
70
21
114
1.86
1.88
1.1
1.7
—
—
—
0
0
30
183
1.65
1.83
1.6
1.7
—
—
—
0
0
57
403
1.43
1.81
1.1
1.1
—
1.05
—
0
6
14
67
2.10
1.76
1.6
1.7
—
—
—
0
0
28
170
1.66
1.74
4.5
5.9
335.61
371.24
umol/l
0.64
23
152
27
163
1.67
1.72
1.6
1.3
—
—
—
0
0
5
13
3.86
1.71
1.4
1.5
69.20
100.46
ng/l
—
5
13
27
164
1.66
1.69
1.0
1.1
—
—
—
0
0
118
946
1.27
1.67
2.1
2.0
340.24
372.78
nmol/l
1.08
105
872
11
227
0.48
1.67
1.5
1.5
—
—
—
0
0
44
301
1.48
1.67
1.2
1.2
—
—
—
0
0
1046
10118
1.20
1.65
4.9
4.4
6.02
5.90
mmol/l
2.08
981
9304
86
1102
0.76
1.63
1.7
1.7
—
—
—
0
0
48
336
1.45
1.63
1.3
1.7
—
—
—
0
0
18
98
1.85
1.62
5.2
5.0
34.54
56.08
u/ml
—
7
30
109
870
1.28
1.61
4.9
3.5
5.88
5.84
kpa
0.19
104
842
74
563
1.33
1.56
2.2
1.8
—
—
—
0
0
43
298
1.46
1.55
1.1
1.1
9.28
6.56
u/ml
—
5
36
21
122
1.73
1.55
1.5
1.5
—
—
—
0
0
21
122
1.73
1.55
1.5
1.5
—
—
—
0
0
11
220
0.50
1.55
1.3
1.4
—
—
—
0
0
11
220
0.50
1.55
1.3
1.4
—
—
—
0
0
13
64
2.04
1.54
2.6
2.0
—
—
—
0
0
11
219
0.50
1.53
1.3
1.4
—
—
—
0
0
11
219
0.50
1.53
1.3
1.4
—
—
—
0
0
5
15
3.34
1.52
3.2
3.5
—
—
—
0
0
43
301
1.44
1.48
1.2
1.2
—
—
—
0
0
31
203
1.54
1.46
1.0
1.1
0.37
2.05
u/ml
2.36
18
106
101
811
1.27
1.44
2.3
2.4
9.21
7.58
ug/l
0.18
92
724
198
1706
1.19
1.44
1.5
1.4
—
—
—
0
0
27
172
1.58
1.43
1.0
1.1
—
—
—
0
0
5
17
2.95
1.36
1.2
1.0
—
—
—
0
0
13
68
1.92
1.33
1.5
2.0
428.25
640.78
e6/l
—
8
60
37
258
1.45
1.32
1.2
1.3
—
—
—
0
0
15
83
1.82
1.31
1.2
1.1
—
—
—
0
0
15
83
1.82
1.31
1.2
1.1
—
—
—
0
0
27
177
1.54
1.29
1.2
1.1
—
12.08
—
0
13
26
169
1.55
1.29
1.0
1.1
1.85
1.81
u/ml
0.01
14
82
8
34
2.36
1.29
5.1
4.5
—
—
—
0
0
15
84
1.80
1.27
1.2
1.1
—
—
—
0
0
15
84
1.80
1.27
1.2
1.1
—
—
—
0
0
15
84
1.80
1.27
1.2
1.1
—
—
—
0
0
35
244
1.45
1.26
2.1
2.2
120.08
89.91
ug/min
0.16
21
151
91
736
1.25
1.25
2.1
2.3
13.40
12.89
nmol/l
0.27
78
674
8
36
2.23
1.24
1.0
1.4
—
—
—
0
0
21
131
1.61
1.24
1.3
1.6
—
—
—
0
0
11
56
1.97
1.22
1.4
1.1
107.73
478.78
u/l
1.20
11
50
5
19
2.64
1.21
12.4
2.5
55.00
127.53
u/l
—
5
19
20
124
1.62
1.21
1.5
1.3
—
—
—
0
0
512
4777
1.12
1.21
3.0
2.5
—
—
—
0
0
42
306
1.39
1.20
2.1
2.1
4024.55
3158.61
u/l
0.14
17
122
20
125
1.61
1.18
1.5
1.5
—
—
—
0
0
37
265
1.41
1.17
1.3
1.2
—
—
—
0
0
258
2312
1.15
1.16
4.5
3.8
24.04
21.03
%
1.87
118
1001
7
30
2.34
1.12
1.3
3.3
—
—
—
0
0
7
30
2.34
1.12
1.3
3.3
—
—
—
0
0
15
89
1.69
1.08
2.3
1.2
1.91
0.84
u/ml
—
9
53
41
305
1.36
1.06
1.5
1.6
0.81
0.08
iu/ml
0.47
12
49
314
2871
1.12
1.03
4.9
4.4
2.27
2.21
ug/l
0.06
291
2596
25
171
1.47
1.02
1.4
1.6
—
—
—
0
0
25
171
1.47
1.02
1.4
1.6
—
—
—
0
0
289
2632
1.13
1.02
4.2
3.8
0.00
0.01
estimate
1.28
80
892
19
123
1.55
1.00
1.0
1.0
1.05
0.45
u/ml
—
8
39
56
442
1.28
0.98
2.0
1.7
—
—
—
0
0
21
140
1.51
0.98
1.7
1.6
—
—
—
0
0
41
310
1.33
0.97
1.4
1.4
208.94
298.97
ug/g
2.07
26
180
7
37
1.90
0.94
1.6
1.2
10.87
8.36
ug/l
—
7
37
23
158
1.46
0.94
1.0
1.0
0.79
2.15
u/ml
—
10
71
25
175
1.44
0.93
1.2
1.5
—
—
—
0
0
49
384
1.29
0.92
2.3
2.0
1.58
2.07
ug/l
0.20
44
341
6
29
2.07
0.89
1.8
1.3
—
—
—
0
0
48
377
1.28
0.89
1.6
1.4
—
—
—
0
0
7
127
0.55
0.88
1.1
1.6
—
—
—
0
0
26
186
1.41
0.87
1.4
1.6
—
—
—
0
0
78
650
1.21
0.87
1.3
1.3
25.52
47.17
au/ml
—
5
41
8
43
1.87
0.87
1.0
1.0
1198.38
1763.16
miu/ml
—
8
43
51
406
1.27
0.86
2.3
1.8
—
—
—
0
0
8
45
1.78
0.84
1.0
1.1
106.35
236.93
iu/ml
—
8
45
8
45
1.78
0.84
1.4
2.0
—
—
—
0
0
8
45
1.78
0.84
1.4
2.0
—
—
—
0
0
16
105
1.53
0.82
1.1
1.5
54.25
56.27
%
—
8
71
12
73
1.65
0.81
1.5
1.5
126.69
170.82
pmol/l
0.63
12
73
32
241
1.34
0.81
1.5
1.6
—
—
—
0
0
106
1221
0.86
0.81
4.6
4.3
32.25
31.84
%
0.13
75
841
67
557
1.21
0.79
1.5
1.6
—
—
—
0
0
19
131
1.46
0.78
1.2
2.0
—
1506.67
—
0
6
28
371
0.75
0.77
1.5
1.5
—
—
—
0
0
24
174
1.39
0.77
1.6
1.7
—
—
—
0
0
136
1205
1.14
0.76
8.2
6.9
—
—
—
0
0
5
24
2.09
0.74
1.2
1.1
—
—
—
0
0
5
25
2.00
0.72
4.0
2.1
—
—
—
0
0
32
246
1.31
0.72
1.5
1.6
—
—
—
0
0
5
27
1.86
0.68
1.2
1.0
—
—
—
0
0
5
27
1.86
0.68
1.0
1.1
—
—
—
0
0
15
102
1.48
0.67
2.6
2.3
—
—
—
0
0
13
86
1.52
0.66
2.4
2.4
—
—
—
0
0
27
206
1.32
0.65
1.7
2.2
138.13
129.41
g/l
0.89
16
156
7
44
1.59
0.65
1.0
1.1
107.57
95.61
%
—
7
38
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
36
288
1.26
0.63
2.5
3.0
0.35
0.36
u/ml
0.03
23
165
22
164
1.35
0.62
1.5
1.2
4.13
5.30
u/ml
—
8
64
39
316
1.24
0.61
2.1
3.0
—
—
—
0
0
26
200
1.31
0.61
1.3
1.4
—
—
—
0
0
9
137
0.65
0.60
1.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
2.3
—
8.37
—
0
11
35
281
1.25
0.60
3.0
3.8
27.82
42.33
mg/l
0.67
29
226
35
281
1.25
0.60
3.0
3.8
50.78
74.76
mg/l
0.48
29
226
10
64
1.57
0.58
1.3
1.1
—
—
—
0
0
12
81
1.49
0.57
1.1
1.1
64.13
39.66
mg/l
0.37
12
66
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
10
65
1.54
0.55
1.1
1.2
—
—
—
0
0
19
142
1.34
0.54
1.1
1.1
1.47
1.51
g/l
0.23
19
130
6
38
1.58
0.54
1.0
1.1
—
—
—
0
0
33
267
1.24
0.54
2.1
1.9
6.92
5.28
iu/l
—
10
93
20
152
1.32
0.52
1.3
1.5
—
—
—
0
0
15
109
1.38
0.51
2.0
1.7
—
—
—
0
0
9
65
1.39
0.50
1.1
1.2
—
—
—
0
0
20
258
0.77
0.50
1.4
1.5
—
—
—
0
0
21
162
1.30
0.50
1.6
1.2
2.86
3.98
u/ml
—
7
43
21
162
1.30
0.50
1.3
1.1
—
—
—
0
0
51
437
1.17
0.49
1.6
1.7
2.57
4.98
mg/l
1.02
39
324
20
154
1.30
0.48
1.5
1.5
0.27
0.34
nmol/l
0.59
12
128
87
777
1.13
0.48
3.1
3.7
1.23
1.23
mmol/l
0.04
78
669
11
76
1.45
0.48
1.0
1.0
—
—
—
0
0
10
68
1.47
0.47
1.1
1.2
—
—
—
0
0
183
1704
1.09
0.46
3.2
2.8
0.67
0.73
ug/l
0.58
131
1018
5
82
0.61
0.46
1.0
1.1
—
81.83
—
0
6
26
210
1.24
0.45
3.2
3.5
23.68
26.23
mg/l
0.11
15
132
111
1013
1.10
0.43
2.9
3.1
—
—
—
0
0
5
31
1.62
0.43
1.0
1.3
—
—
—
0
0
8
57
1.41
0.42
1.0
1.0
—
—
—
0
0
61
539
1.14
0.41
1.1
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
33
390
0.84
0.40
1.7
1.8
—
—
—
0
0
0
18
0.00
0.40
0.0
2.1
—
0.63
—
0
13
13
97
1.34
0.39
1.7
2.6
—
—
—
0
0
31
261
1.19
0.38
1.2
1.2
—
—
—
0
0
23
188
1.23
0.37
1.6
1.5
99.00
109.90
u/ml
—
7
42
17
134
1.27
0.37
1.3
1.5
—
—
—
0
0
10
135
0.74
0.36
1.4
1.5
—
—
—
0
0
10
135
0.74
0.36
1.4
1.5
—
—
—
0
0
10
135
0.74
0.36
1.4
1.5
—
—
—
0
0
31
361
0.86
0.34
1.6
1.7
—
—
—
0
0
24
200
1.20
0.33
1.4
1.4
—
—
—
0
0
24
200
1.20
0.33
1.4
1.4
—
—
—
0
0
10
133
0.75
0.33
1.4
1.5
—
—
—
0
0
10
74
1.35
0.32
1.1
1.1
—
—
—
0
0
6
47
1.28
0.32
1.5
1.7
0.92
5.42
nmol/l
—
6
41
10
132
0.76
0.32
1.4
1.5
—
—
—
0
0
10
132
0.76
0.32
1.4
1.5
—
—
—
0
0
60
541
1.11
0.32
1.2
1.4
—
—
—
0
0
80
734
1.10
0.31
1.3
1.2
171.28
145.87
iu/ml
0.17
25
299
120
1123
1.08
0.30
2.0
1.9
—
—
—
0
0
7
56
1.25
0.29
1.1
2.1
—
—
—
0
0
30
260
1.16
0.29
1.7
1.3
525.23
496.34
mg/l
0.17
30
246
252
2422
1.05
0.28
2.6
2.3
—
—
—
0
0
8
67
1.20
0.26
1.6
1.3
—
—
—
0
0
8
67
1.20
0.26
1.8
1.5
7.88
8.10
u/l
—
8
58
8
67
1.20
0.26
1.6
1.3
—
—
—
0
0
6
83
0.72
0.24
2.2
1.4
—
—
—
0
0
25
218
1.15
0.23
4.6
2.3
1.26
0.88
nmol/l
1.73
20
189
35
313
1.12
0.23
1.5
1.3
—
—
—
0
0
7
91
0.77
0.22
1.0
1.0
—
—
—
0
0
10
79
1.27
0.22
1.5
1.2
—
—
—
0
0
27
238
1.14
0.22
1.8
1.2
4.11
3.82
mmol/l
0.42
27
223
5
42
1.19
0.21
1.2
1.2
—
77.00
—
0
5
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
7.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.09
—
0
7
5
43
1.16
0.21
1.6
2.1
12.48
213.30
ug/l
—
5
36
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
40
365
1.10
0.20
3.8
3.4
50.32
3580.77
u/ml
0.72
34
315
6
50
1.20
0.19
1.0
1.1
—
—
—
0
0
6
53
1.13
0.18
1.2
1.1
—
—
—
0
0
56
522
1.08
0.18
1.3
1.3
38.76
31.31
iu/l
0.83
49
445
7
61
1.15
0.17
1.7
1.5
—
—
—
0
0
10
82
1.22
0.17
1.1
1.0
291.80
286.94
mg/l
—
10
72
105
1003
1.05
0.17
2.1
1.9
—
—
—
0
0
12
102
1.18
0.15
1.0
1.1
—
—
—
0
0
135
1395
0.96
0.13
1.7
1.8
1.48
1.46
%
0.11
119
1236
25
228
1.10
0.13
1.3
1.4
—
—
—
0
0
62
589
1.06
0.13
2.7
4.1
1.78
1.82
mmol/l
0.03
46
452
15
134
1.12
0.11
1.1
1.3
0.57
0.67
nmol/l
0.66
15
127
19
173
1.10
0.10
1.4
1.5
—
—
—
0
0
12
106
1.13
0.09
1.1
1.7
—
—
—
0
0
30
282
1.07
0.09
1.4
1.4
14.87
9.63
u/l
0.59
24
230
10
113
0.88
0.08
1.8
2.3
29.60
34.94
mg/l
—
5
29
6
73
0.82
0.07
1.0
1.4
1.49
1.55
g/l
—
6
73
8
77
1.04
0.07
1.5
1.7
—
—
—
0
0
97
946
1.03
0.07
2.7
2.2
0.22
0.21
g/l
0.24
90
896
8
78
1.03
0.07
14.9
15.8
853.13
842.01
nmol/l
—
8
73
9
85
1.06
0.07
1.7
1.6
—
—
—
0
0
11
122
0.90
0.07
1.2
1.1
—
—
—
0
0
9
87
1.03
0.07
1.1
1.6
0.98
1.00
g/l
—
9
87
17
183
0.93
0.06
2.2
2.5
17.43
16.12
%
—
10
103
23
217
1.06
0.06
5.0
1.7
—
—
—
0
0
10
90
1.11
0.05
2.3
3.3
63.80
52.32
%
—
10
83
14
151
0.93
0.05
2.0
1.7
—
—
—
0
0
22
231
0.95
0.04
1.9
1.6
—
—
—
0
0
35
361
0.97
0.03
1.5
1.5
—
—
—
0
0
100
986
1.02
0.03
4.6
4.3
6.45
26.33
ug/l
1.40
79
798
14
134
1.05
0.00
1.1
1.3
—
0.52
—
0
10
11
108
1.02
0.00
1.5
1.4
25.28
33.70
g/l
1.61
11
94
11
108
1.02
0.00
1.5
1.2
—
—
—
0
0
12
118
1.02
0.00
1.0
1.1
—
—
—
0
0
22
218
1.01
0.00
1.4
1.2
—
—
—
0
0
19
187
1.02
0.00
3.9
3.6
4.00
4.22
e9/l
0.21
19
187
19
195
0.97
0.00
4.3
3.9
57.26
58.41
%
0.20
19
195
14
145
0.97
0.00
2.8
3.3
1.64
1.27
%
0.31
14
134
20
205
0.98
0.00
1.5
1.2
236.18
225.29
u/ml
0.06
15
130
9
93
0.97
-0.00
3.3
4.0
—
—
—
0
0
6
61
0.98
-0.00
1.3
1.2
—
—
—
0
0
5
53
0.94
-0.00
1.8
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.0
—
—
—
0
0
5
53
0.94
-0.00
1.2
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
93
0.97
-0.00
1.0
1.6
—
—
—
0
0
9
93
0.97
-0.00
1.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
79
0.89
-0.00
2.1
1.4
84.29
77.37
umol/l
—
7
79
9
93
0.97
-0.00
1.0
1.6
—
—
—
0
0
5
51
0.98
-0.00
2.0
1.9
—
—
—
0
0
5
53
0.94
-0.00
1.2
1.4
—
—
—
0
0
5
50
1.00
-0.00
1.6
3.1
—
—
—
0
0
5
52
0.96
-0.00
1.8
1.6
—
—
—
0
0
7
69
1.01
-0.00
1.4
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_CORNEALNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CORNEALNAS | 1.154 [0.99, 1.34] | 0.064 |
| Birth year | 0.992 [0.98, 1.0] | 0.064 |
During the follow-up period (1.1.1998 — 31.12.2019), 407 out of 3842 females with H7_CORNEALNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CORNEALNAS | 1.221 [1.03, 1.44] | 0.019 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 340 out of 3257 males with H7_CORNEALNAS died.
Mortality risk
Mortality risk for people of age
years, who have H7_CORNEALNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.096% | 0.159% |
| 5 | 0.622% | 1.398% |
| 10 | 1.589% | 3.359% |
| 15 | 2.881% | 6.346% |
| 20 | 4.996% | 10.9% |
Relationships between endpoints
↥Index endpoint: H7_CORNEALNAS – Other and unspecified corneal deformities and disorders
GWS hits: 5
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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