cranial nerve palsy: Injury to any of the cranial nerves or their nuclei in the brain resulting in muscle weakness.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
508 |
4. Check minimum number of eventsNone |
508 |
5. Include endpointsNone |
508 |
6. Filter based on genotype QC (FinnGen only) |
508 |
Control definitions (FinnGen only)
- Control exclude
- G6_NERPLEX
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Postzoster neuralgia
based on the number of shared cases.
Similar with more cases:
- Nerve, nerve root and plexus disorders
- Neurological diseases
- Neurological diseases, wide definition
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3542 | 2189 | 1325 |
| Only index persons | 3234 | 2038 | 1196 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.04 |
| Only index persons | 0.06 | 0.07 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 75.27 | 76.62 | 72.99 |
| Only index persons | 74.95 | 76.35 | 72.58 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 508 | 295 | 213 |
| Unadjusted period prevalence (%) | 0.10 | 0.10 | 0.09 |
| Median age at first event (years) | 72.36 | 71.95 | 72.92 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 440
- Matched controls
- 4402
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G53.0
ICD-10 Finland
Postzoster neuralgia
443.5
212.5
197
8
G53.0*B02.20
ICD-10 Finland
Trigeminal neuralgia after shingles
+∞
184.8
164
*
B02.9
ICD-10 Finland
Zoster without complication
20.8
119.3
190
155
N03AX16
ATC
pregabalin; oral
10.2
103.9
271
598
N03AX12
ATC
gabapentin; oral
12.1
102.8
220
336
G53.0*B02.21
ICD-10 Finland
Postherpetic geniculate ganglionitis
1141.1
96.8
91
*
J05AB11
ATC
valaciclovir; oral
11.5
95.6
208
319
J05AB01
ATC
aciclovir; systemic
9.1
91.4
245
533
G530, B028
ICD-10 Finland
NA
+∞
55.4
52
*
N02AX02
ATC
tramadol; systemic, rectal
5.0
54.8
293
1251
B02.8
ICD-10 Finland
Zoster with other complications
50.2
47.6
57
13
B02
ICD-10 Finland
Zoster [herpes zoster]
12.3
44.6
84
83
S70
ICPC
Herpes zoster
12.4
32.1
59
54
G50.0
ICD-10 Finland
Trigeminal neuralgia
118.6
31.1
33
*
N03AF01
ATC
carbamazepine; oral, rectal
7.8
29.1
70
104
N06AX21
ATC
duloxetine; oral
5.7
28.8
89
186
N06AA09
ATC
amitriptyline; systemic
5.3
27.2
90
203
G56.0
ICD-10 Finland
Carpal tunnel syndrome
13.8
26.5
46
37
H02AB06
ATC
prednisolone; systemic
3.0
26.2
260
1440
N02AA05
ATC
oxycodone; systemic
3.6
23.9
127
446
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.8
23.6
239
1307
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.6
22.6
120
419
B02.20
ICD-10 Finland
Herpes zoster trigeminal neuralgia
84.5
21.9
24
*
A02BC02
ATC
pantoprazole; systemic
2.7
20.2
325
2237
N02AJ06
ATC
codeine and paracetamol; systemic
2.7
20.1
188
952
B02.21
ICD-10 Finland
Herpes zoster neuralgia in another cranial nerve
+∞
19.9
19
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.7
19.8
182
906
R51.80
ICD-10 Finland
Headache
3.8
19.8
93
291
G51.0
ICD-10 Finland
Bell palsy
110.0
19.7
21
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
18.8
243
1454
J01DB01
ATC
cefalexin; oral
3.0
18.7
370
2807
M79.6
ICD-10 Finland
Pain in limb
2.6
18.6
185
958
H19.2*B02.3
ICD-10 Finland
Keratitis and keratoconjunctivitis (interstitial) in zoster
34.6
18.1
23
7
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.6
17.5
175
900
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.2
17.3
104
391
B02.3
ICD-10 Finland
Zoster ocular disease
31.4
16.3
21
7
G530, B029
ICD-10 Finland
NA
+∞
15.7
15
*
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
10.6
15.7
30
30
M54.5
ICD-10 Finland
Low back pain
2.5
15.6
161
831
N06AX16
ATC
venlafaxine; oral
3.5
15.4
78
257
R50.9
ICD-10 Finland
Fever, unspecified
3.3
15.1
83
290
R07.4
ICD-10 Finland
Chest pain, unspecified
2.4
14.9
156
809
N02BE01
ATC
paracetamol; systemic, rectal
3.1
14.9
394
3232
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.8
14.5
110
474
N03AX09
ATC
lamotrigine; oral
8.1
14.4
32
42
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.0
13.9
86
326
S01AD03
ATC
aciclovir; ophthalmic
5.5
13.7
41
81
R53
ICD-10 Finland
Malaise and fatigue
2.5
13.7
127
612
H03.1*B02.3
ICD-10 Finland
Zoster blepharitis
77.6
13.7
15
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.2
13.6
77
274
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.3
13.5
173
982
A01
ICPC
Pain general/multiple sites
3.6
13.4
64
201
A02BC05
ATC
esomeprazole; systemic
2.2
13.3
201
1223
R06.0
ICD-10 Finland
Dyspnoea
2.4
13.3
143
744
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.2
13.2
51
133
G44.2
ICD-10 Finland
Tension-type headache
3.2
13.0
73
259
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
3.1
12.9
74
266
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
12.9
154
838
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
12.6
152
831
G63.0*B02.29
ICD-10 Finland
Postherpetic polyneuropathy
133.7
12.5
13
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.7
12.5
92
389
G50.1
ICD-10 Finland
Atypical facial pain
18.7
12.1
18
10
ZX120
NOMESCO Finland
Intravenous
3.3
12.0
63
212
L28
ICPC
Limited function/disability (L)
2.5
11.9
108
509
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.2
11.9
45
115
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
11.5
110
532
M03BX02
ATC
tizanidine; oral
2.0
11.5
247
1707
J01AA02
ATC
doxycycline; systemic
2.2
11.5
346
2743
ACC51
NOMESCO Finland
Release of median nerve
36.1
11.3
14
*
M25.5
ICD-10 Finland
Pain in joint
2.3
11.0
121
628
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
4.5
11.0
39
94
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.1
10.9
34
71
R03AC02
ATC
salbutamol; inhalant
2.0
10.9
225
1517
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
4.0
10.9
44
120
A02BC01
ATC
omeprazole; systemic
2.1
10.8
146
828
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.5
10.8
95
442
H22.0*B02.3
ICD-10 Finland
Zoster iridocyclitis
61.5
10.7
12
*
R52.2
ICD-10 Finland
Other chronic pain
6.3
10.5
27
45
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
10.5
104
513
G530, B022
ICD-10 Finland
NA
+∞
10.5
10
*
N01
ICPC
Headache
3.5
10.5
50
157
R11
ICD-10 Finland
Nausea and vomiting
3.2
10.4
56
192
L03
ICPC
Low back symptom/complaint
2.2
9.7
111
581
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.4
9.7
90
426
AA1AD
NOMESCO Finland
CT of head and brain
2.1
9.7
132
749
S01
ICPC
Pain/tenderness of skin
4.4
9.6
34
82
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.4
9.6
46
145
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.4
9.6
90
431
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.0
9.4
146
872
R05
ICD-10 Finland
Cough
2.3
9.3
95
472
H04.10
ICD-10 Finland
Dry eye syndrome
2.9
9.3
57
213
J01FA10
ATC
azithromycin; systemic
1.9
9.1
221
1546
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
5.5
9.1
26
50
N05CF01
ATC
zopiclone; oral
1.9
8.9
163
1029
M01AH05
ATC
etoricoxib; oral
1.8
8.9
232
1658
C03CA01
ATC
furosemide; systemic
1.9
8.9
183
1207
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.0
8.9
35
94
WW500
NOMESCO Finland
Blood transfusion
4.5
8.8
30
70
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.6
8.8
67
284
J01FA09
ATC
clarithromycin; systemic
2.0
8.8
129
749
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
14.4
8.7
14
10
TAB00
NOMESCO Finland
Lumbar puncture
5.7
8.7
24
44
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.7
8.7
59
236
L04AX01
ATC
azathioprine; systemic
4.5
8.7
30
71
J01MA12
ATC
levofloxacin; systemic
2.2
8.7
102
537
R51.81
ICD-10 Finland
Facial pain NOS
8.5
8.7
18
22
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
8.3
205
1428
N03AF02
ATC
oxcarbazepine; oral
5.3
8.3
24
47
M01AB05
ATC
diclofenac; systemic, rectal
1.8
8.3
273
2089
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.1
8.2
110
610
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
8.1
176
1170
J45.9
ICD-10 Finland
Asthma, unspecified
2.2
8.1
89
455
TAC00
NOMESCO Finland
Peripheral nerve block
34.0
8.1
10
*
B00.9
ICD-10 Finland
Herpesviral infection, unspecified
34.0
8.1
10
*
S18
ICPC
Laceration/cut
1.8
8.1
186
1263
M54.3
ICD-10 Finland
Sciatica
3.7
8.1
34
97
M79.1
ICD-10 Finland
Myalgia
2.6
8.1
60
251
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.5
8.0
68
305
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.1
8.0
43
148
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.6
8.0
58
241
M48.0
ICD-10 Finland
Spinal stenosis
2.5
8.0
66
295
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.3
8.0
23
45
M54.4
ICD-10 Finland
Lumbago with sciatica
2.5
7.9
65
289
H60.9
ICD-10 Finland
Otitis externa, unspecified
3.6
7.8
34
100
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
7.7
199
1393
M04AA01
ATC
allopurinol; systemic
2.2
7.7
78
385
XQ800
NOMESCO Finland
Prick test
3.7
7.7
32
91
R52.0
ICD-10 Finland
Acute pain
5.3
7.7
22
43
XG410
NOMESCO Finland
Flow-volume spirometry
4.3
7.6
27
66
L03AA02
ATC
filgrastim; parenteral
5.6
7.6
21
39
XW000
NOMESCO Finland
Bone marrow biopsy
3.5
7.5
34
103
A07AA02
ATC
nystatin; oral
3.1
7.5
42
146
A46
ICD-10 Finland
Erysipelas
2.2
7.4
78
388
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.5
7.4
59
255
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.6
7.4
32
94
R05
ICPC
Cough
2.0
7.4
104
590
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
4.4
7.3
25
59
L05
ICPC
Flank/axilla symptom/complaint
3.3
7.3
35
111
G530, B0229
ICD-10 Finland
NA
+∞
7.3
7
*
R02
ICPC
Shortness of breath/dyspnoea
2.4
7.3
64
295
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
7.2
158
1043
B01AB05
ATC
enoxaparin; parenteral
1.8
7.2
147
949
B00.10
ICD-10 Finland
Herpes simplex facialis
30.6
7.2
9
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.2
7.1
74
369
UJF32
NOMESCO Finland
Coloscopy
1.9
7.1
123
753
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
7.0
121
739
SPAT1263
SPAT
Sampling
1.7
7.0
187
1313
R52.9
ICD-10 Finland
Pain, unspecified
2.7
7.0
45
175
M01AE02
ATC
naproxen; oral, rectal
1.7
7.0
223
1652
127
Kela drug reimbursment
Transplant complication
8.5
6.9
14
17
N03AE01
ATC
clonazepam; systemic
3.4
6.9
32
100
H02AB04
ATC
methylprednisolone; systemic
2.1
6.8
80
421
B02.2
ICD-10 Finland
Zoster with other nervous system involvement
40.7
6.8
8
*
B00.19
ICD-10 Finland
Other vesicular dermatitis caused by the herper simplex virus
17.0
6.8
10
6
D07AC01
ATC
betamethasone; topical
1.8
6.7
150
991
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.5
6.7
30
91
N06AA10
ATC
nortriptyline; systemic
5.3
6.7
19
37
H19.2
ICD-10 Finland
Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
22.9
6.7
9
*
H02AB09
ATC
hydrocortisone; systemic
6.6
6.7
16
25
S19
ICPC
Skin injury other
4.0
6.7
25
65
SPAT1254
SPAT
Administration of medicine
2.1
6.7
83
445
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.7
6.6
43
168
M01AE01
ATC
ibuprofen; systemic, rectal
1.9
6.6
358
3080
J01MA02
ATC
ciprofloxacin; systemic
1.7
6.5
183
1294
M01AC01
ATC
piroxicam; systemic, rectal
2.2
6.5
66
326
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.9
6.5
25
67
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
6.5
112
681
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.9
6.4
94
538
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.5
6.4
21
48
A03FA01
ATC
metoclopramide; systemic, rectal
1.9
6.4
97
562
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.7
6.4
188
1345
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
6.4
167
1159
N05BB01
ATC
hydroxyzine; systemic
3.0
6.4
36
128
H01
ICPC
Ear pain/earache
2.6
6.3
47
197
K08.80
ICD-10 Finland
Toothache NOS
3.2
6.3
31
101
M70.6
ICD-10 Finland
Trochanteric bursitis
2.2
6.3
62
299
R06AE09
ATC
levocetirizine; oral
2.3
6.3
56
260
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.4
6.3
53
239
G56.2
ICD-10 Finland
Lesion of ulnar nerve
18.3
6.3
9
5
H62.1*B02.8
ICD-10 Finland
Otitis externa in zoster
+∞
6.3
6
*
L01BB05
ATC
fludarabine; systemic
+∞
6.3
6
*
B02.29
ICD-10 Finland
Herpes zoster polyneuropathy
+∞
6.3
6
*
WX109
NOMESCO Finland
Extensive surface anesthesy of skin with external ointment or geel
+∞
6.3
6
*
S29
ICPC
Skin symptom/complaint other
2.0
6.3
82
450
C08CA01
ATC
amlodipine; oral
1.7
6.2
178
1261
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.1
6.2
72
374
R42
ICD-10 Finland
Dizziness and giddiness
1.8
6.2
116
724
M01AC06
ATC
meloxicam; systemic, rectal
1.7
6.2
156
1066
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.9
6.1
93
537
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.5
6.1
47
203
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.5
6.1
44
184
J01FF01
ATC
clindamycin; systemic
1.8
6.1
118
744
SPAT1229
SPAT
Assessment of need for aid
2.4
6.1
51
229
J01CA04
ATC
amoxicillin; systemic
1.7
6.0
320
2684
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.8
6.0
126
813
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
25
19
13.79
26.43
2.6
2.1
16.4
11.5
%
0.70
12
11
23
17
14.12
24.66
1.3
1.1
—
—
—
0
0
232
1270
2.52
22.67
2.7
2.1
317.7
272.3
u/l
0.17
217
1185
164
785
2.61
20.97
2.8
1.8
—
—
—
0
0
327
2151
2.46
20.60
8.2
6.0
11.2
12.1
umol/l
0.99
320
2028
327
2165
2.43
20.09
9.0
6.1
1.2
1.2
mmol/l
0.12
281
1817
305
1963
2.39
19.92
8.0
5.4
1.2
1.2
mmol/l
1.42
278
1755
35
63
5.89
18.93
4.1
6.0
184.0
219.1
iu/ml
—
5
8
416
3129
2.82
18.68
11.5
7.1
76.7
80.4
u/l
0.98
402
2903
113
474
2.78
18.55
7.4
4.0
272.6
246.0
u/l
0.83
108
445
133
607
2.61
18.47
2.7
2.2
2.3
2.3
g/l
0.23
124
560
397
2931
2.62
18.29
6.4
3.9
15.4
14.0
mm/h
0.91
381
2648
332
2271
2.33
18.06
13.3
8.7
4.6
4.2
e9/l
2.16
299
1967
285
1833
2.26
17.94
10.8
5.5
25.7
26.4
%
0.44
271
1687
22
25
9.15
17.78
2.6
1.9
576.1
638.8
e6/l
0.12
13
12
282
1815
2.24
17.60
10.0
5.3
59.5
58.4
%
0.65
269
1684
140
670
2.50
17.50
2.7
2.2
12.2
12.6
umol/l
0.25
135
617
126
575
2.58
17.40
2.9
2.2
21.5
21.9
%
0.09
111
497
34
66
5.45
16.98
2.3
1.3
80.0
—
titre
—
5
0
264
1672
2.21
16.94
3.6
2.7
307.6
132.6
ug/l
1.18
245
1507
21
24
9.08
16.88
1.3
1.3
—
—
—
0
0
343
2431
2.27
16.37
7.1
4.6
6.8
6.7
mmol/l
0.35
330
2269
19
21
9.36
15.64
2.8
2.1
—
—
—
0
0
285
1903
2.13
15.47
6.9
4.3
33.7
34.9
g/l
2.31
265
1763
160
854
2.28
15.36
2.1
1.7
1.2
1.3
mg/l
0.42
133
671
246
1572
2.10
14.79
5.1
3.3
—
—
—
0
0
205
1229
2.12
14.55
3.5
2.3
54.8
56.5
u/l
0.38
192
1129
257
1691
2.05
14.05
6.2
3.9
43.0
63.1
ng/l
0.46
202
1262
71
270
2.89
13.79
1.8
1.4
—
—
—
0
0
231
1472
2.04
13.70
4.6
3.0
1847.3
1632.3
ng/l
0.30
208
1276
26
48
5.65
13.67
2.4
2.8
1143.3
867.4
u/ml
—
6
5
19
25
7.86
13.64
1.4
1.2
—
—
—
0
0
129
659
2.28
13.54
4.5
3.0
0.8
0.8
mmol/l
1.44
118
611
38
99
4.07
13.32
2.1
1.6
—
—
—
0
0
111
536
2.37
13.25
7.5
4.6
1.0
1.0
mmol/l
0.14
103
485
80
332
2.67
13.15
2.8
1.9
344.7
396.7
nmol/l
1.46
75
302
189
1141
2.05
12.82
2.6
2.1
3.4
3.2
mg/l
0.34
160
958
114
567
2.30
12.67
2.6
1.8
—
—
—
0
0
320
2336
2.00
12.45
3.9
3.0
62.8
50.9
u/l
1.16
294
2132
248
1661
1.96
12.40
2.8
2.2
79.9
79.4
nmol/l
0.10
223
1447
378
2939
2.12
12.21
4.4
3.8
15.3
15.0
pmol/l
1.07
345
2597
41
120
3.63
12.20
3.5
1.6
216.0
226.7
titre
—
5
6
112
562
2.27
12.15
2.5
1.8
—
—
—
0
0
13
12
11.09
12.00
3.2
1.3
—
—
—
0
0
167
991
2.02
11.68
4.3
2.6
2527.4
10458.1
umol/l
2.09
145
837
459
3906
2.82
11.41
33.4
15.7
23.9
26.0
mg/l
0.66
409
3148
27
61
4.62
11.33
4.5
3.8
0.9
1.9
%
0.68
21
53
73
311
2.57
11.33
2.1
1.6
—
—
—
0
0
20
36
5.74
10.78
4.7
3.5
51.5
56.3
%
0.28
14
29
261
1857
1.83
10.15
2.5
2.1
91.1
93.4
pmol/l
0.34
154
935
191
1234
1.88
10.12
4.9
3.2
0.5
0.6
e6/l
0.16
150
939
132
754
2.01
10.07
3.8
2.8
1.5
1.3
e6/l
0.19
86
424
76
349
2.38
10.01
3.1
2.8
64.1
65.9
g/l
1.20
70
315
148
884
1.95
9.92
6.9
3.9
665.9
255.3
ng/l
0.57
131
752
24
55
4.53
9.90
1.7
1.6
—
—
—
0
0
27
68
4.14
9.89
1.7
1.6
—
—
—
0
0
52
200
2.78
9.84
1.6
1.8
1.4
1.6
g/l
0.85
45
180
116
645
2.03
9.48
30.0
28.8
1.4
1.3
inr
0.20
23
76
24
57
4.37
9.48
1.7
1.6
—
—
—
0
0
25
62
4.19
9.35
1.8
1.5
—
—
—
0
0
32
95
3.53
9.33
2.2
1.6
—
—
—
0
0
80
388
2.26
9.27
2.6
2.5
28.4
30.4
u/l
0.36
69
324
269
1977
1.77
8.99
3.1
2.7
—
—
—
0
0
58
247
2.52
8.97
6.9
3.7
2.2
1.9
mmol/l
0.18
42
191
219
1519
1.78
8.92
3.4
3.3
2.4
2.4
mmol/l
0.04
190
1301
83
420
2.17
8.65
3.3
2.5
5.0
6.3
ug/l
0.26
74
359
268
1988
1.74
8.49
5.2
4.0
0.0
0.0
estimate
0.00
51
380
96
525
2.02
8.13
6.8
6.7
2.2
1.4
mmol/l
1.49
80
410
12
17
7.21
8.02
3.7
3.8
—
—
—
0
0
420
3584
1.99
8.00
5.8
4.7
1.9
2.3
mu/l
0.69
395
3197
179
1202
1.76
7.95
4.2
3.1
34.7
32.9
u/l
0.15
171
1143
40
150
2.81
7.94
2.8
3.0
—
—
—
0
0
463
4108
2.43
7.83
35.4
18.8
139.3
139.6
mmol/l
1.19
457
3988
463
4115
2.41
7.67
35.7
18.9
4.0
4.0
mmol/l
0.87
457
3987
151
975
1.78
7.63
3.2
2.2
—
—
—
0
0
20
49
4.21
7.60
1.3
1.3
—
—
—
0
0
168
1120
1.75
7.59
2.0
1.6
21.3
20.8
nmol/l
0.15
153
947
44
178
2.61
7.56
3.3
1.8
—
—
—
0
0
265
2001
1.68
7.53
6.6
5.4
0.0
0.0
estimate
0.00
53
370
65
315
2.22
7.51
2.3
1.7
—
—
—
0
0
18
41
4.51
7.48
1.7
1.6
—
—
—
0
0
92
510
1.98
7.47
1.3
1.2
7.1
13.6
u/ml
0.71
28
176
66
325
2.18
7.33
4.1
3.3
96.2
87.7
ng/l
0.41
59
280
266
2020
1.67
7.32
5.4
4.1
0.0
0.0
estimate
0.00
50
372
97
552
1.94
7.29
1.4
1.2
35.8
40.4
iu/ml
0.12
28
176
63
307
2.20
7.18
5.6
3.1
57.4
59.0
ml/min/173m2
0.11
30
132
11
16
7.01
7.17
1.2
1.1
—
—
—
0
0
114
688
1.85
7.15
2.4
1.8
30.2
29.7
s
0.46
108
663
16
35
4.69
6.97
1.9
1.6
—
—
—
0
0
38
149
2.68
6.95
2.0
2.0
44.4
39.7
u/l
0.62
32
131
24
72
3.45
6.91
2.4
1.7
—
—
—
0
0
116
711
1.82
6.90
4.4
3.1
1.2
2.8
e6/l
3.21
71
384
461
4127
2.26
6.86
17.4
10.5
23.6
23.9
u/l
0.19
451
3951
43
182
2.49
6.74
1.6
1.2
753.7
203.0
u/ml
0.67
38
166
18
45
4.11
6.67
1.9
1.6
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
12
21
5.83
6.61
1.3
1.1
—
—
—
0
0
14
29
4.94
6.49
1.0
1.0
—
—
—
0
0
11
18
6.22
6.45
1.2
1.3
—
—
—
0
0
35
137
2.67
6.43
4.0
3.5
158.6
116.6
mg/l
0.13
26
105
35
137
2.67
6.43
4.0
3.5
44.9
54.7
mg/l
0.15
28
107
244
1857
1.60
6.34
6.0
4.1
—
—
—
0
0
145
970
1.69
6.29
1.7
1.7
442.2
434.5
pmol/l
0.13
121
791
25
82
3.15
6.28
1.4
1.3
32.4
1527.2
e6/l
0.54
20
63
25
82
3.15
6.28
1.2
1.2
13.7
12.8
e6/l
0.02
20
59
13
26
5.11
6.25
2.0
1.6
—
—
—
0
0
35
139
2.63
6.25
1.4
1.3
—
—
—
0
0
81
456
1.92
6.25
4.3
2.8
7.8
9.6
umol/l
0.62
71
401
39
164
2.49
6.21
3.0
1.7
—
—
—
0
0
31
116
2.78
6.20
1.3
1.5
—
—
—
0
0
80
451
1.92
6.14
3.7
3.3
3.1
1.8
mmol/l
2.49
67
358
10
16
6.36
5.97
2.2
3.6
865.4
1103.4
u/ml
—
10
16
75
419
1.93
5.91
7.4
7.6
114.6
120.2
g/l
1.72
75
403
20
60
3.43
5.78
2.0
1.6
—
—
—
0
0
11
21
5.33
5.54
2.3
1.6
—
—
—
0
0
15
38
4.04
5.48
2.5
2.6
—
—
—
0
0
33
137
2.51
5.41
3.3
2.4
0.9
1.0
g/l
0.04
26
114
10
18
5.65
5.34
1.2
1.1
—
—
—
0
0
417
3687
1.73
5.32
28.3
15.1
70.0
74.3
ml/min/173m2
3.29
359
3040
11
22
5.09
5.28
2.5
1.7
—
—
—
0
0
11
22
5.09
5.28
2.3
1.6
—
—
—
0
0
11
22
5.09
5.28
2.5
1.7
—
—
—
0
0
11
22
5.09
5.28
2.5
1.7
—
—
—
0
0
11
22
5.09
5.28
2.5
1.7
—
—
—
0
0
414
3658
1.71
5.24
6.8
6.1
41.3
40.3
mmol/mol
1.27
374
3346
139
963
1.61
5.13
1.9
1.8
1115.8
1216.9
nmol/l
0.70
109
710
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
33
142
2.42
5.03
3.7
2.3
0.3
0.3
u/ml
0.03
24
83
15
43
3.56
4.64
1.3
1.3
94.7
126.7
u/ml
—
6
7
426
3828
1.70
4.64
5.5
4.8
6.0
6.0
mmol/l
0.11
387
3419
26
104
2.58
4.62
1.8
1.6
—
—
—
0
0
71
422
1.79
4.60
3.5
3.1
326.0
254.7
ng/l
0.42
66
394
15
44
3.48
4.50
1.2
1.4
—
—
—
0
0
15
44
3.48
4.50
1.3
1.4
—
—
—
0
0
15
44
3.48
4.50
1.2
1.4
—
—
—
0
0
384
3379
1.56
4.40
30.2
17.6
37.8
38.6
%
0.72
234
2181
15
45
3.40
4.35
1.2
1.4
—
—
—
0
0
15
45
3.40
4.35
1.3
1.4
—
—
—
0
0
15
45
3.40
4.35
1.3
1.4
—
—
—
0
0
152
1111
1.53
4.35
6.0
4.4
0.0
0.0
estimate
0.00
48
361
21
78
2.77
4.30
1.4
1.3
—
—
—
0
0
22
84
2.69
4.28
1.2
1.4
—
—
—
0
0
7
6
11.80
4.28
1.0
1.0
—
—
—
0
0
66
398
1.76
4.08
2.2
2.2
0.2
0.2
g/l
0.09
60
369
14
42
3.40
4.07
2.3
1.6
—
—
—
0
0
14
42
3.40
4.07
2.3
1.6
—
—
—
0
0
14
42
3.40
4.07
2.3
1.6
—
—
—
0
0
106
727
1.58
4.00
1.2
1.2
0.7
1.6
u/ml
1.77
26
184
31
145
2.21
3.95
3.4
2.1
3.1
3.2
g/l
0.28
24
112
165
1251
1.47
3.89
3.9
2.9
6.7
7.0
mmol/l
0.32
140
1036
16
54
3.03
3.88
1.0
1.1
—
—
—
0
0
33
160
2.14
3.86
8.5
4.1
24.5
25.0
mmol/l
0.39
28
149
25
108
2.38
3.82
2.0
1.4
—
—
—
0
0
6
5
12.12
3.77
1.3
1.0
—
—
—
0
0
6
5
12.12
3.77
1.3
1.0
75.8
87.6
%
—
6
5
22
90
2.51
3.77
3.5
2.2
117.6
126.2
g/l
0.80
17
63
31
149
2.15
3.71
3.5
2.1
9.5
10.1
g/l
0.38
25
126
28
129
2.24
3.71
3.5
2.3
38.5
36.6
g/l
1.37
23
106
170
1308
1.45
3.68
4.2
3.7
13.7
8.2
mg/mmol
0.61
117
821
16
56
2.92
3.66
1.1
1.1
—
—
—
0
0
122
882
1.50
3.60
6.2
4.6
1.0
1.0
kg/l
0.09
13
125
21
86
2.50
3.59
4.1
2.4
13.5
15.7
%
1.53
11
38
21
86
2.50
3.59
1.1
1.1
—
—
—
0
0
7
9
7.87
3.57
1.1
1.2
—
—
—
0
0
32
160
2.07
3.48
3.4
2.1
3.4
3.7
g/l
0.67
24
110
32
160
2.07
3.48
3.4
2.1
7.3
7.4
g/l
0.10
24
114
32
160
2.07
3.48
3.4
2.1
—
—
—
0
0
10
27
3.76
3.37
1.0
1.0
—
—
—
0
0
400
3621
1.49
3.36
4.5
4.0
1.4
1.2
mmol/l
3.36
362
3227
17
65
2.67
3.33
1.2
1.2
—
2.6
—
0
7
193
1544
1.40
3.30
5.8
4.4
—
—
—
0
0
124
916
1.47
3.27
3.2
3.1
2.5
2.5
mmol/l
0.55
106
809
20
84
2.44
3.27
1.1
1.5
—
—
—
0
0
7
11
6.43
3.19
3.7
2.4
116.3
105.4
%
—
7
11
9
20
4.56
3.12
1.2
1.2
—
—
—
0
0
6
8
7.57
3.06
2.3
1.6
—
—
—
0
0
7
12
5.90
3.03
1.4
1.1
—
—
—
0
0
409
3744
1.47
3.01
5.0
4.4
1.4
1.5
mmol/l
2.07
372
3370
17
69
2.51
2.99
1.2
1.1
—
—
—
0
0
5
5
10.08
2.98
1.2
1.0
—
—
—
0
0
9
22
4.15
2.89
1.2
1.1
3.2
1.9
mmol/l
—
9
22
422
3896
1.49
2.88
5.6
5.1
2.6
2.6
mmol/l
0.48
389
3509
27
137
2.03
2.86
3.9
3.1
1.0
0.9
nmol/l
0.35
21
109
411
3783
1.45
2.78
5.1
4.4
4.5
4.5
mmol/l
0.21
374
3428
12
42
2.90
2.76
2.8
1.7
—
—
—
0
0
5
6
8.40
2.75
1.8
1.5
—
—
—
0
0
21
98
2.19
2.74
2.0
1.6
—
—
—
0
0
8
19
4.26
2.69
1.5
1.2
—
—
—
0
0
10
32
3.17
2.66
1.4
1.0
—
—
—
0
0
60
397
1.58
2.64
3.0
2.6
4.6
4.4
kpa
0.43
60
378
14
55
2.59
2.63
11.1
2.2
32.8
32.3
pg
0.11
14
55
22
107
2.10
2.61
1.6
1.4
—
—
—
0
0
22
107
2.10
2.61
1.6
1.4
—
—
—
0
0
11
38
2.94
2.59
1.3
1.0
—
—
—
0
0
8
20
4.05
2.57
1.1
1.2
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
5
7
7.20
2.55
1.0
1.4
92.6
107.9
%
—
5
7
22
109
2.06
2.50
2.1
1.4
—
—
—
0
0
11
39
2.86
2.49
1.0
1.3
264.7
273.7
pmol/l
—
6
30
12
45
2.71
2.46
1.2
1.2
—
—
—
0
0
13
51
2.59
2.46
3.3
4.1
—
—
—
0
0
14
58
2.45
2.39
4.0
2.8
4.3
4.6
e9/l
0.22
14
58
13
52
2.54
2.37
6.7
5.3
11.6
11.4
mg/l
0.05
13
47
18
85
2.16
2.31
2.2
1.8
—
—
—
0
0
13
53
2.49
2.29
2.7
1.6
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
5
9
5.60
2.22
1.2
4.0
279.6
108.2
%
—
5
9
18
88
2.08
2.14
1.3
1.4
4246.8
26174.9
e6/l
—
10
57
8
25
3.23
2.10
1.1
1.0
—
—
—
0
0
14
62
2.29
2.09
5.8
3.1
59.6
60.1
%
0.05
14
62
54
369
1.52
2.09
6.9
3.6
1.2
1.2
mmol/l
0.14
46
324
11
44
2.53
2.02
2.2
2.0
710.1
7077.3
u/l
—
6
13
10
39
2.60
1.93
1.3
1.7
—
—
—
0
0
25
143
1.79
1.92
1.3
1.2
—
—
—
0
0
25
144
1.77
1.88
1.3
1.2
—
—
—
0
0
12
53
2.29
1.82
1.3
1.0
—
—
—
0
0
7
23
3.07
1.80
1.3
1.4
—
—
—
0
0
7
23
3.07
1.80
1.3
1.4
—
—
—
0
0
10
41
2.47
1.76
1.2
1.1
—
—
—
0
0
10
41
2.47
1.76
3.1
1.7
—
—
—
0
0
20
111
1.83
1.71
2.1
1.9
—
—
—
0
0
10
42
2.41
1.68
1.3
1.2
—
—
—
0
0
13
62
2.13
1.67
1.3
1.2
—
—
—
0
0
8
32
2.52
1.60
1.5
1.2
—
—
—
0
0
70
533
1.36
1.56
14.1
7.6
—
—
—
0
0
5
15
3.36
1.52
1.4
1.4
—
—
—
0
0
5
15
3.36
1.52
1.4
1.4
—
—
—
0
0
9
37
2.46
1.48
1.3
1.0
—
—
—
0
0
5
16
3.15
1.44
4.0
1.9
—
—
—
0
0
5
16
3.15
1.44
4.0
1.9
—
—
—
0
0
5
16
3.15
1.44
4.0
1.9
—
—
—
0
0
6
22
2.75
1.44
1.5
2.2
—
—
—
0
0
6
22
2.75
1.44
1.0
1.6
—
—
—
0
0
6
22
2.75
1.44
1.0
1.6
—
—
—
0
0
152
1300
1.24
1.41
5.4
5.3
2.5
2.9
ug/l
0.40
131
1145
119
990
1.26
1.41
1.7
1.6
1.4
1.3
mmol/l
0.81
100
808
125
1048
1.26
1.38
4.8
4.5
22.3
21.8
%
0.10
59
539
9
41
2.22
1.37
1.0
1.0
—
—
—
0
0
12
217
0.54
1.29
1.7
1.7
—
—
—
0
0
18
107
1.71
1.27
1.1
1.2
—
—
—
0
0
59
453
1.34
1.27
1.8
1.4
—
—
—
0
0
14
78
1.82
1.22
1.1
1.1
—
—
—
0
0
5
19
2.65
1.22
1.4
1.7
0.8
1.0
g/l
—
5
19
5
20
2.51
1.15
1.2
1.3
—
—
—
0
0
19
119
1.62
1.13
1.2
1.4
358.2
275.4
ug/g
1.62
11
64
31
224
1.41
0.99
2.3
2.1
12.7
12.2
nmol/l
0.07
22
193
27
191
1.44
0.97
1.3
1.3
—
—
—
0
0
63
511
1.27
0.94
4.5
4.5
29.6
32.5
%
1.44
43
322
89
751
1.22
0.94
3.3
3.1
0.8
0.8
ug/l
0.05
55
523
6
28
2.16
0.91
1.5
1.4
0.3
0.3
nmol/l
—
6
21
6
29
2.08
0.89
3.3
1.8
—
—
—
0
0
57
466
1.25
0.82
1.5
1.4
—
—
—
0
0
58
476
1.25
0.81
6.4
3.6
—
—
—
0
0
9
54
1.68
0.75
1.4
1.8
—
—
—
0
0
5
26
1.93
0.71
3.4
3.7
—
—
—
0
0
7
43
1.64
0.67
1.1
1.3
0.6
0.6
nmol/l
—
7
38
8
49
1.64
0.62
1.0
1.0
—
—
—
0
0
28
220
1.29
0.58
2.9
1.8
—
—
—
0
0
6
35
1.72
0.58
1.2
1.6
—
—
—
0
0
13
91
1.44
0.53
2.8
1.7
—
—
—
0
0
6
40
1.51
0.51
1.5
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
433.3
—
0
7
24
195
1.24
0.41
1.2
1.2
195.6
140.2
iu/ml
—
8
74
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
24
201
1.20
0.33
3.0
1.7
—
—
—
0
0
12
94
1.28
0.28
1.3
1.3
—
—
—
0
0
54
490
1.11
0.28
2.5
4.0
5.0
38.0
ug/l
1.27
45
415
7
92
0.76
0.22
1.9
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
8.0
—
0
7
0
14
0.00
0.20
0.0
2.9
—
13.2
—
0
14
5
70
0.71
0.17
1.4
1.4
—
—
—
0
0
8
69
1.16
0.16
2.5
1.6
35.6
44.6
nmol/l
—
8
63
16
166
0.96
0.00
1.1
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
32.1
—
0
6
Mortality – FinRegistry
↥Association
Association between endpoint G6_POSTZOST and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_POSTZOST | 1.259 [1.07, 1.48] | 0.005 |
| Birth year | 0.995 [0.99, 1.0] | 0.291 |
During the follow-up period (1.1.1998 — 31.12.2019), 668 out of 1848 females with G6_POSTZOST died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_POSTZOST | 1.483 [1.21, 1.82] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.031 |
During the follow-up period (1.1.1998 — 31.12.2019), 466 out of 1086 males with G6_POSTZOST died.
Mortality risk
Mortality risk for people of age
years, who have G6_POSTZOST.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.109% | 0.277% |
| 5 | 0.642% | 1.793% |
| 10 | 1.732% | 4.78% |
| 15 | 3.376% | 8.816% |
| 20 | 6.006% | 14.731% |
Relationships between endpoints
↥Index endpoint: G6_POSTZOST – Postzoster neuralgia
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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