Mesial bite

K11_MESIAL_BITE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K07.21
  • Hospital discharge: ICD-10 K07.21
  • Cause of death: ICD-10 K07.21

3 out of 7 registries used, show all original rules.

382

4. Check minimum number of events

None

382

5. Include endpoints

None

382

6. Filter based on genotype QC (FinnGen only)

364

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8284 4430 3837
Only index persons 7332 3977 3355
Unadjusted period prevalence (%)
Whole population 0.12 0.13 0.11
Only index persons 0.14 0.15 0.13
Median age at first event (years)
Whole population 11.24 11.42 10.94
Only index persons 12.14 12.32 11.94

-FinnGen-

Key figures

All Female Male
Number of individuals 364 258 106
Unadjusted period prevalence (%) 0.08 0.09 0.05
Median age at first event (years) 27.13 27.94 25.17

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
382
Matched controls
3820
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
+∞
307.7
382
*
K07.24
ICD-10 Finland
Open bite
40.2
185.3
120
43
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
13.1
103.0
115
122
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
57.4
87.6
50
10
K07.14
ICD-10 Finland
Retrognaty, maxillary
46.7
82.0
49
12
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
8.5
73.7
116
187
SBB10
NOMESCO Finland
Dental impressions
6.1
68.8
186
511
EB1MA
NOMESCO Finland
Cephalometry with X-ray
6.9
57.4
108
207
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
6.3
45.4
89
175
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
5.3
42.6
105
254
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
7.2
39.1
64
104
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
5.0
38.5
101
256
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
5.4
36.4
84
190
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
6.8
34.5
59
100
K07.13
ICD-10 Finland
Retrognaty, mandibular
8.4
33.9
47
63
EEC05
NOMESCO Finland
Le Fort I osteotomy
128.1
33.3
35
*
SJC10
NOMESCO Finland
Orthodontic band in one tooth
5.1
33.1
81
192
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
4.7
32.4
88
227
SAA04
NOMESCO Finland
Special examination of mouth
4.5
32.3
95
261
K07.60
ICD-10 Finland
Snapping jaw
5.5
31.0
67
142
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
3.9
30.5
118
395
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
4.3
29.5
90
253
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
4.2
26.2
82
234
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
3.7
25.3
100
335
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
6.5
24.9
43
73
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.0
24.2
245
1412
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
3.8
24.0
86
269
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
4.4
23.7
68
181
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
29.4
22.6
30
11
SAA03
NOMESCO Finland
Extended examination of mouth
3.0
22.0
268
1671
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
3.9
21.1
72
217
WZC00
NOMESCO Finland
Treatment plan or consultation
2.8
21.0
209
1163
SXC05
NOMESCO Finland
Other oral or dental procedure
3.2
20.2
100
382
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
3.2
19.5
92
341
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
3.6
18.2
68
217
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
3.2
17.7
81
293
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
4.0
16.7
51
141
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
3.2
16.0
71
251
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
3.2
15.2
69
247
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
35.5
13.6
17
5
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
5.7
13.2
25
46
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
2.9
12.5
66
257
OIKK, ,
NOMESCO Finland
2.7
12.0
72
300
K07.10
ICD-10 Finland
Asymmetry of jaw
23.8
11.7
16
7
SAA02
NOMESCO Finland
Basic examination of mouth
3.2
11.6
342
2789
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
3.4
11.4
44
142
K03.66
ICD-10 Finland
Tooth plaque
2.7
11.1
65
267
SAA01
NOMESCO Finland
Simple examination of mouth
2.7
10.5
329
2669
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
4.0
10.4
30
79
D82
ICPC
Teeth/gum disease
2.0
10.4
193
1278
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.0
9.8
208
1436
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
2.9
9.6
49
186
K00.00
ICD-10 Finland
Hypodontia
4.3
9.3
24
58
F45.8
ICD-10 Finland
Other somatoform disorders
2.7
9.2
51
203
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
37.6
9.1
11
*
SDA03
NOMESCO Finland
Periodontal treatment
1.9
9.0
169
1108
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
4.7
8.7
20
44
WZA90
NOMESCO Finland
Other medical or dental certificate
2.0
8.6
133
815
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
2.2
8.2
84
441
KAY20, ,
NOMESCO Finland
3.8
8.2
25
69
EBA00
NOMESCO Finland
Extraction of tooth
1.9
7.9
181
1250
K03.64
ICD-10 Finland
Dental calculus supragingival
1.8
7.8
177
1218
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
6.6
7.8
19
30
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
25.6
7.6
10
*
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
2.0
7.5
106
624
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
7.3
151
1005
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
16.1
7.3
11
7
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
14.1
6.9
11
8
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
6.9
102
608
SPAT1263
SPAT
Sampling
1.8
6.9
176
1244
K07.61
ICD-10 Finland
Cracking jaw joint
3.7
6.7
21
59
K03.00
ICD-10 Finland
Approximal wear
2.6
6.7
38
153
SPAT1310
SPAT
Counselling related to known health issue
1.8
6.6
147
993
EBB10
NOMESCO Finland
Insertion of dental implant
10.3
6.6
12
12
OIKH, ,
NOMESCO Finland
2.3
6.6
50
231
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
5.9
6.5
17
30
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
6.5
133
876
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
2.0
6.4
85
487
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
5.7
6.4
17
31
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
18.4
6.3
9
5
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.7
6.3
166
1175
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
2.5
6.3
42
183
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
7.2
6.3
14
20
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
27.2
6.3
8
*
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
4.1
6.2
17
43
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.8
6.2
109
685
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.8
6.2
135
905
EBB15
NOMESCO Finland
Insertion of dental implant abutment
12.8
6.1
10
8

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
47
213
2.38
6.45
3.3
3.7
—
—
—
0
0
22
72
3.18
5.59
1.5
1.3
—
—
—
0
0
90
586
1.70
4.38
3.2
2.9
—
—
—
0
0
9
21
4.36
3.01
1.4
1.1
149.74
176.76
pmol/l
—
9
21
52
328
1.68
2.82
1.4
1.5
1067.92
1161.41
nmol/l
0.30
31
248
114
864
1.46
2.75
2.5
2.3
—
—
—
0
0
32
177
1.88
2.69
1.8
1.8
7.11
8.29
u/l
0.34
23
145
35
210
1.73
2.29
1.7
1.7
23.08
14.80
iu/l
0.88
28
173
9
30
3.05
2.16
1.1
1.2
—
—
—
0
0
7
20
3.54
2.06
1.3
1.4
—
—
—
0
0
9
34
2.69
1.87
1.3
1.6
—
—
—
0
0
44
301
1.52
1.75
1.2
1.2
—
—
—
0
0
30
188
1.65
1.72
3.4
4.2
0.13
0.50
%
—
8
58
6
20
3.03
1.58
1.2
1.1
—
—
—
0
0
121
1432
0.77
1.54
4.0
3.1
0.00
0.00
estimate
-0.00
25
284
148
1707
0.78
1.53
2.8
2.8
—
—
—
0
0
302
2820
1.34
1.52
5.0
4.4
1.95
2.24
mu/l
0.31
272
2634
97
1180
0.76
1.52
3.5
2.9
6.40
5.89
ph
—
10
99
6
21
2.89
1.51
1.0
1.3
—
—
—
0
0
7
28
2.53
1.46
3.1
2.3
34914.29
39346.61
ug/l
—
7
28
263
2418
1.28
1.44
4.5
3.8
14.46
14.37
pmol/l
0.24
235
2205
5
16
3.15
1.44
2.6
3.6
—
—
—
0
0
28
182
1.58
1.42
3.8
4.8
0.17
0.02
%
—
6
47
53
394
1.40
1.41
1.2
1.6
430.45
19533955.17
pmol/l
0.50
40
343
11
53
2.11
1.40
3.9
3.3
26.02
27.91
mg/l
—
5
33
29
191
1.56
1.39
3.6
4.9
0.00
0.12
%
—
7
56
0
40
0.00
1.33
0.0
1.2
—
—
—
0
0
16
267
0.58
1.32
1.9
2.1
27.45
30.46
u/l
0.29
11
218
46
338
1.41
1.31
1.8
1.6
—
—
—
0
0
9
43
2.12
1.31
2.4
1.5
12.99
13.06
%
—
9
43
49
645
0.72
1.31
5.5
3.1
—
—
—
0
0
276
2569
1.27
1.28
4.0
3.3
5.67
5.62
mmol/l
0.28
249
2369
82
997
0.77
1.26
4.8
3.7
25.58
75.93
e6/l
2.10
60
667
30
205
1.50
1.24
3.7
4.7
0.38
0.77
%
—
8
71
340
3262
1.38
1.19
9.6
9.0
—
—
—
0
0
26
373
0.67
1.13
1.2
1.3
—
—
—
0
0
125
1429
0.81
1.10
4.7
4.3
0.00
0.00
estimate
-0.00
24
280
5
21
2.40
1.09
2.6
1.7
—
—
—
0
0
20
129
1.58
1.08
2.8
2.4
90.53
104.95
ng/l
0.13
15
122
56
698
0.77
1.04
3.0
3.5
7.39
7.40
ph
0.46
11
117
165
1478
1.20
1.02
6.0
6.8
—
—
—
0
0
24
340
0.69
0.99
1.3
1.8
—
—
—
0
0
195
1781
1.19
0.96
7.1
9.0
3.85
3.82
e9/l
0.09
169
1553
0
32
0.00
0.95
0.0
1.3
—
295.00
—
0
6
220
2037
1.19
0.91
6.0
6.5
84.70
81.87
u/l
0.29
204
1901
5
101
0.49
0.91
1.2
1.2
—
—
—
0
0
129
1447
0.84
0.90
3.9
3.1
0.00
0.00
estimate
-0.00
24
274
25
178
1.43
0.89
10.0
5.5
—
—
—
0
0
116
1018
1.20
0.87
1.4
1.4
1.70
1.86
u/ml
0.07
20
237
6
31
1.95
0.84
2.7
6.2
—
—
—
0
0
137
1224
1.19
0.84
3.0
2.6
69.77
71.46
nmol/l
0.29
120
1130
6
112
0.53
0.84
3.3
2.4
—
—
—
0
0
177
1619
1.17
0.82
5.5
6.8
0.19
0.18
e9/l
0.35
153
1452
28
208
1.37
0.80
1.6
2.0
3.01
4.22
e9/l
3.02
17
190
42
524
0.78
0.80
4.1
2.8
586.26
578.75
mosm/kgh2o
0.06
31
453
0
26
0.00
0.78
0.0
3.0
—
176.15
—
0
13
0
27
0.00
0.77
0.0
1.1
—
—
—
0
0
86
743
1.20
0.77
2.5
2.6
15.56
21.15
ng/l
0.50
46
350
103
906
1.19
0.75
7.8
8.4
1.20
1.13
inr
0.36
30
282
7
38
1.86
0.74
1.7
1.5
—
—
—
0
0
14
206
0.67
0.73
1.4
1.3
—
—
—
0
0
5
25
2.01
0.73
1.4
1.2
—
—
—
0
0
26
341
0.75
0.72
1.6
1.8
—
—
—
0
0
110
978
1.18
0.71
3.3
5.1
37.71
37.37
g/l
0.33
96
917
116
1036
1.17
0.71
2.0
1.9
—
—
—
0
0
5
26
1.93
0.71
2.2
1.9
93.68
91.61
%
—
5
26
26
339
0.75
0.69
1.6
1.8
—
—
—
0
0
128
1410
0.86
0.68
6.2
8.1
0.00
0.00
e9/l
-0.00
106
1132
73
629
1.20
0.67
2.0
2.1
166.05
280.93
u/l
0.54
63
595
16
112
1.45
0.64
2.2
1.6
—
—
—
0
0
27
343
0.77
0.61
1.9
1.8
—
—
—
0
0
0
20
0.00
0.60
0.0
14.0
—
12.36
—
0
20
0
21
0.00
0.60
0.0
2.0
—
36.57
—
0
21
25
320
0.77
0.60
1.6
1.8
—
—
—
0
0
67
769
0.84
0.60
5.0
6.9
—
—
—
0
0
11
162
0.67
0.60
1.5
1.5
—
—
—
0
0
74
842
0.85
0.59
2.5
2.6
—
—
—
0
0
176
1639
1.14
0.59
5.4
6.3
2.05
2.07
e9/l
0.07
157
1482
155
1432
1.14
0.59
5.4
6.6
0.67
0.64
%
0.32
142
1345
258
2464
1.15
0.59
3.6
3.2
1.16
1.20
mmol/l
0.38
231
2314
168
1563
1.13
0.57
5.5
6.4
31.86
31.10
%
0.40
159
1485
15
206
0.72
0.57
2.7
2.5
0.62
0.75
ug/l
—
6
114
98
879
1.15
0.57
1.7
1.7
102.58
96.49
pmol/l
0.51
52
453
37
303
1.24
0.57
1.3
1.3
23.86
159.64
iu/ml
—
7
120
166
1544
1.13
0.56
5.0
6.2
54.01
54.68
%
0.32
157
1465
41
340
1.23
0.56
4.4
4.0
1.51
1.79
ug/l
0.30
33
301
81
717
1.16
0.56
1.5
1.7
—
—
—
0
0
146
1348
1.13
0.56
3.0
2.6
—
—
—
0
0
11
159
0.68
0.55
1.5
1.4
—
—
—
0
0
12
82
1.48
0.55
1.0
1.6
—
57.78
—
0
9
58
500
1.19
0.55
3.1
3.4
63.20
80.77
mg/l
0.13
31
335
42
351
1.22
0.54
1.9
2.0
—
—
—
0
0
28
223
1.28
0.54
1.7
1.6
251.36
311.52
mu/l
1.32
28
206
11
158
0.69
0.54
1.5
1.4
—
—
—
0
0
69
606
1.17
0.53
1.6
2.2
0.75
0.94
mg/l
0.69
48
427
60
522
1.18
0.51
4.0
4.0
11.86
11.43
mg/mmol
0.01
37
343
86
770
1.15
0.51
2.5
2.5
53.67
55.61
u/l
0.32
72
706
33
271
1.24
0.50
1.2
1.3
—
—
—
0
0
119
1092
1.13
0.50
7.7
7.3
1.23
1.22
mmol/l
1.23
105
1014
36
429
0.82
0.49
3.7
3.0
5.77
3.96
e6/l
0.37
22
225
7
46
1.53
0.48
1.3
1.1
—
—
—
0
0
95
1042
0.88
0.47
1.7
1.6
—
—
—
0
0
159
1491
1.11
0.46
5.4
6.4
2.93
2.80
%
0.30
148
1407
62
699
0.87
0.45
4.4
3.0
1.01
1.02
kg/l
—
10
91
73
813
0.87
0.45
4.3
3.2
23.94
39.92
e6/l
0.44
55
622
237
2273
1.11
0.44
5.0
4.2
37.64
37.77
mmol/mol
0.08
217
2145
7
51
1.38
0.44
1.0
1.0
—
—
—
0
0
14
185
0.75
0.44
1.1
1.1
—
—
—
0
0
8
56
1.44
0.43
2.5
2.5
—
—
—
0
0
5
32
1.57
0.42
3.4
2.6
—
—
—
0
0
5
33
1.52
0.41
3.4
2.2
1.12
1.75
mmol/l
—
5
33
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
1325.56
—
0
16
159
1499
1.10
0.41
5.9
6.7
7.84
8.15
%
0.69
147
1416
0
17
0.00
0.40
0.0
1.5
—
6.47
—
0
17
8
61
1.32
0.39
1.5
2.3
11.22
10.23
mg/l
—
8
56
5
35
1.43
0.39
1.8
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
13
170
0.76
0.39
2.0
2.1
—
—
—
0
0
84
767
1.12
0.38
3.0
3.2
8.56
8.55
mmol/l
0.01
71
688
68
752
0.88
0.38
5.0
3.3
0.00
0.00
estimate
0.50
23
274
42
365
1.17
0.38
1.2
1.2
—
—
—
0
0
61
679
0.88
0.38
2.9
4.5
93.82
93.28
%
0.07
61
670
9
68
1.33
0.38
15.3
4.8
—
—
—
0
0
60
537
1.14
0.37
1.5
1.3
17.79
22.44
iu/ml
0.39
27
165
128
1198
1.10
0.37
7.9
7.6
1.23
1.22
mmol/l
0.68
108
1055
61
675
0.89
0.35
1.8
1.7
1.29
1.32
mmol/l
0.10
50
599
27
315
0.85
0.32
1.7
1.2
—
—
—
0
0
60
545
1.12
0.31
2.4
2.4
121.81
106.53
ug/g
0.15
42
414
39
344
1.15
0.31
1.6
1.9
—
—
—
0
0
7
100
0.69
0.31
7.0
16.4
—
—
—
0
0
56
507
1.12
0.30
1.3
1.4
19.60
20.91
nmol/l
0.31
44
438
11
84
1.32
0.30
1.0
1.6
—
—
—
0
0
77
711
1.10
0.30
1.9
2.2
2.91
2.79
mg/l
0.18
68
605
165
1577
1.08
0.30
3.0
2.8
67.89
74.23
ug/l
0.30
156
1479
70
760
0.90
0.30
4.2
3.1
—
—
—
0
0
28
322
0.86
0.28
1.4
1.5
—
—
—
0
0
29
252
1.16
0.28
2.9
3.8
0.23
0.23
g/l
0.00
24
239
164
1571
1.08
0.28
5.4
6.4
0.53
0.53
e9/l
0.21
143
1385
69
746
0.91
0.27
4.2
3.2
0.09
0.31
e6/l
3.15
53
556
164
1573
1.07
0.27
5.4
6.4
0.04
0.04
e9/l
0.04
143
1387
8
67
1.20
0.26
7.0
7.3
—
—
—
0
0
309
3141
0.92
0.25
10.1
10.2
16.78
20.83
mg/l
1.71
247
2276
23
265
0.86
0.24
1.6
1.8
—
—
—
0
0
10
126
0.79
0.24
1.2
1.2
0.57
3.63
u/ml
—
5
78
314
3187
0.92
0.23
8.7
8.4
26.90
24.93
u/l
0.71
304
3075
23
263
0.87
0.23
4.0
3.3
—
—
—
0
0
5
40
1.25
0.22
1.0
1.4
—
—
—
0
0
10
124
0.80
0.22
2.7
2.2
0.31
0.14
e6/l
—
10
118
30
335
0.89
0.22
2.1
4.4
4.13
6.98
umol/l
1.80
25
285
26
293
0.88
0.21
6.7
7.7
6.04
5.83
kpa
0.81
26
286
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
12.7
—
48.25
—
0
10
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
8
102
0.78
0.21
2.8
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
1.00
—
0
12
0
12
0.00
0.21
0.0
1.7
—
112.92
—
0
12
0
12
0.00
0.21
0.0
1.4
—
8.17
—
0
12
38
417
0.90
0.21
2.9
3.1
721.94
677.57
ng/l
0.03
18
249
198
2036
0.94
0.21
4.9
3.9
—
—
—
0
0
105
1000
1.07
0.21
2.4
2.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.7
—
32.71
—
0
7
0
13
0.00
0.21
0.0
1.0
—
264.63
—
0
8
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
20
229
0.87
0.20
11.3
10.2
25.11
25.11
mmol/l
0.00
20
229
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
9
113
0.79
0.20
1.0
1.1
—
—
—
0
0
87
824
1.07
0.20
2.5
3.0
2.39
2.37
mmol/l
1.20
72
736
6
49
1.23
0.20
2.8
2.9
—
—
—
0
0
112
1071
1.06
0.20
1.9
2.0
—
—
—
0
0
6
50
1.20
0.20
1.7
1.8
—
—
—
0
0
6
51
1.18
0.19
3.0
4.0
2.15
7.53
u/ml
—
6
51
6
51
1.18
0.19
1.2
1.3
—
—
—
0
0
57
532
1.08
0.19
1.4
1.2
11.80
7.15
u/ml
0.21
20
207
17
196
0.86
0.19
7.4
9.4
1.06
1.23
mmol/l
0.92
17
189
16
185
0.86
0.18
1.6
1.4
—
—
—
0
0
7
60
1.17
0.18
5.6
3.7
54.71
53.65
%
—
7
60
96
917
1.06
0.17
1.2
1.4
2.23
1.94
g/l
0.80
52
549
7
63
1.11
0.17
1.7
1.3
—
—
—
0
0
17
194
0.87
0.17
1.2
1.2
—
—
—
0
0
8
70
1.15
0.16
4.0
3.4
—
—
—
0
0
15
171
0.87
0.15
12.1
12.4
97.52
96.52
%
0.92
15
164
27
246
1.10
0.15
2.0
2.2
—
—
—
0
0
217
2129
1.04
0.14
4.7
3.7
7.74
8.60
mm/h
0.65
201
1974
10
84
1.20
0.14
1.0
2.9
1.97
1.22
g/l
—
10
75
12
103
1.17
0.14
1.2
1.1
—
—
—
0
0
8
98
0.81
0.14
1.5
1.8
—
—
—
0
0
24
263
0.91
0.13
5.9
7.4
4.73
4.78
kpa
0.05
24
257
25
273
0.91
0.13
1.4
1.5
—
—
—
0
0
28
258
1.09
0.13
4.9
5.1
1.61
1.59
%
0.04
23
237
19
172
1.11
0.11
1.4
1.2
—
—
—
0
0
26
240
1.09
0.11
1.2
1.3
—
—
—
0
0
23
250
0.91
0.11
8.3
8.0
105.74
104.65
mmol/l
0.61
23
250
13
115
1.14
0.10
2.5
3.8
18.10
9.00
umol/l
—
8
90
14
156
0.89
0.10
12.4
12.0
124.21
123.11
g/l
0.06
14
151
263
2602
1.03
0.09
4.1
3.5
4.67
4.64
mmol/l
0.15
239
2462
6
56
1.07
0.08
2.3
2.6
—
—
—
0
0
354
3557
0.93
0.08
15.4
15.3
40.61
40.31
%
0.48
329
3357
18
195
0.92
0.08
10.7
11.3
5.01
5.15
kpa
0.46
18
185
18
195
0.92
0.08
10.7
11.3
13.44
14.01
kpa
0.22
18
186
5
65
0.77
0.08
1.4
1.1
—
—
—
0
0
155
1524
1.03
0.08
4.7
5.0
6.27
6.29
mmol/l
0.05
137
1359
260
2576
1.03
0.07
4.2
3.4
1.42
1.47
mmol/l
1.51
234
2429
54
559
0.96
0.07
3.7
2.6
8.77
8.45
e6/l
0.04
45
497
30
316
0.95
0.07
2.5
1.6
—
—
—
0
0
355
3565
0.94
0.07
15.4
15.2
136.76
135.42
g/l
1.12
349
3512
13
118
1.11
0.07
12.7
11.6
95.62
94.59
%
0.79
13
118
8
94
0.85
0.06
1.3
2.1
—
—
—
0
0
18
193
0.93
0.06
10.7
11.5
1.07
0.93
mmol/l
0.11
13
157
26
274
0.95
0.06
1.5
1.4
—
—
—
0
0
355
3563
0.95
0.05
15.3
15.1
6.61
6.68
e9/l
0.31
343
3455
37
356
1.04
0.05
9.7
8.3
1.21
1.15
mmol/l
0.50
30
337
52
505
1.03
0.05
1.7
1.6
—
—
—
0
0
66
645
1.03
0.04
1.4
1.5
—
—
—
0
0
355
3561
0.96
0.04
15.4
15.1
4.63
4.55
e12/l
2.15
343
3455
11
101
1.09
0.04
18.7
11.3
24.25
24.26
mmol/l
0.00
11
94
202
2004
1.02
0.04
3.2
3.1
65.56
34.71
u/l
0.92
192
1912
84
827
1.02
0.03
3.6
2.4
—
—
—
0
0
355
3560
0.96
0.03
15.3
15.0
29.69
29.85
pg
0.92
349
3508
263
2617
1.02
0.03
4.3
3.7
2.86
2.79
mmol/l
0.67
237
2462
83
842
0.98
0.03
1.7
1.7
—
—
—
0
0
295
2938
1.02
0.03
10.7
10.8
139.76
139.64
mmol/l
0.42
287
2840
295
2940
1.01
0.02
10.4
10.8
3.91
3.90
mmol/l
0.16
283
2831
355
3558
0.97
0.02
15.3
15.0
88.92
89.24
fl
0.63
349
3506
18
173
1.04
0.01
2.8
2.0
—
—
—
0
0
128
1272
1.01
0.01
4.7
6.5
10.35
10.80
umol/l
0.33
118
1193
11
116
0.95
0.00
1.5
1.6
—
—
—
0
0
20
194
1.03
0.00
1.6
1.3
—
—
—
0
0
33
336
0.98
0.00
2.3
2.4
354.65
3483.39
u/l
2.23
15
119
37
364
1.02
0.00
5.1
6.3
0.84
0.81
mmol/l
1.82
32
348
52
526
0.99
0.00
2.6
4.1
—
—
—
0
0
13
128
1.02
0.00
1.5
1.6
120.40
216.35
u/ml
—
7
65
18
182
0.99
0.00
6.7
3.2
—
—
—
0
0
18
182
0.99
0.00
1.3
1.4
175.39
255.64
miu/ml
0.58
12
93
26
259
1.00
0.00
8.6
11.0
—
—
—
0
0
10
97
1.03
0.00
11.0
9.4
—
—
—
0
0
17
167
1.02
0.00
2.4
4.4
4.29
34.58
ug/l
—
9
130
355
3555
0.98
0.00
15.5
15.1
263.08
260.38
e9/l
0.34
345
3451
19
186
1.02
0.00
1.8
1.5
—
—
—
0
0
10
100
1.00
-0.00
5.1
5.6
0.73
0.68
%
—
10
100
0
6
0.00
-0.00
0.0
1.2
—
83.00
—
0
6
0
5
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
93
0.97
-0.00
1.1
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
56
560
1.00
-0.00
2.8
2.9
313.00
4351.22
umol/l
1.83
47
500
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
10.7
—
26.18
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
28.4
—
0.46
—
0
7
0
7
0.00
-0.00
0.0
2.4
—
137.14
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
907.20
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
3.94
—
0
8
0
5
0.00
-0.00
0.0
12.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
-0.00
1.0
1.1
—
—
—
0
0
7
75
0.93
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
—
—
0
0
8
88
0.91
-0.00
1.1
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
8.0
—
—
—
0
0
7
71
0.99
-0.00
3.4
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
10.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
-0.00
1.6
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
16.10
—
0
8
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_MESIAL_BITE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_MESIAL_BITE.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: K11_MESIAL_BITE – Mesial bite

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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