This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Symptoms and signs involving the digestive system and abdomen
R18_SYMPTOMS_SIGNS_INVOLVI_DIGES_SYSTEM_ABDOMEN
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
155743 |
4. Check minimum number of eventsNone |
155743 |
5. Include endpoints |
164541 |
6. Filter based on genotype QC (FinnGen only) |
164541 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- R
- Name in latin
- Symptomata et signa ad systema digestorium et abdomen pertinentia
Similar endpoints
↥List of similar endpoints to
Symptoms and signs involving the digestive system and abdomen
based on the number of shared cases.
Similar with more cases:
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 164541 | 109534 | 55007 |
| Unadjusted period prevalence (%) | 32.96 | 37.34 | 24.25 |
| Median age at first event (years) | 46.62 | 41.55 | 56.73 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 835
- Matched controls
- 4516
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
70.2
323.0
521
104
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
+∞
71.0
86
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
14.8
67.7
137
59
R11
ICD-10 Finland
Nausea and vomiting
22.5
58.9
103
28
R10.1
ICD-10 Finland
Pain localized to upper abdomen
16.1
46.8
91
34
A02BC02
ATC
pantoprazole; systemic
2.8
30.5
266
643
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.4
26.7
114
155
A02BC05
ATC
esomeprazole; systemic
3.4
26.2
158
291
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.8
22.9
89
109
R13
ICD-10 Finland
Dysphagia
57.9
21.6
31
*
N02BE01
ATC
paracetamol; systemic, rectal
2.1
20.9
422
1489
R10.0
ICD-10 Finland
Acute abdomen
27.3
20.8
34
7
N02AX02
ATC
tramadol; systemic, rectal
2.5
18.5
176
431
K35.9
ICD-10 Finland
Acute appendicitis, unspecified
4.0
18.4
86
127
JEA00
NOMESCO Finland
Appendectomy
4.3
16.7
72
98
A02BC01
ATC
omeprazole; systemic
2.8
16.5
129
279
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
116.3
15.8
21
*
UJF32
NOMESCO Finland
Coloscopy
3.5
15.7
86
145
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
+∞
15.4
19
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
14.4
143
354
JN3BD
NOMESCO Finland
Extensive abdominal CT
7.3
14.4
39
30
R10.2
ICD-10 Finland
Pelvic and perineal pain
19.9
14.3
25
7
J01AA02
ATC
doxycycline; systemic
1.8
14.0
357
1308
D01
ICPC
Abdominal pain/cramps general
3.7
13.8
69
108
JN3AD
NOMESCO Finland
Abdominal CT examination
7.8
13.8
36
26
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
5.5
13.0
43
44
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.2
12.5
147
394
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
8.8
12.4
30
19
M01AE02
ATC
naproxen; oral, rectal
1.8
11.5
289
1035
K59.0
ICD-10 Finland
Constipation
4.3
11.0
45
59
R53
ICD-10 Finland
Malaise and fatigue
2.4
11.0
102
243
J01MA02
ATC
ciprofloxacin; systemic
2.0
11.0
175
532
J01MA12
ATC
levofloxacin; systemic
3.1
10.9
68
127
R50.9
ICD-10 Finland
Fever, unspecified
2.4
10.5
104
256
A02BC03
ATC
lansoprazole; oral
2.3
10.5
110
278
J01FA06
ATC
roxithromycin; oral
1.9
10.3
191
614
UJF30
NOMESCO Finland
Ileoscopy through colon
4.6
9.8
37
45
M03BX02
ATC
tizanidine; oral
1.7
9.7
252
903
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
4.6
9.5
36
44
R03AC02
ATC
salbutamol; inhalant
1.7
9.3
289
1088
P01AB01
ATC
metronidazole; oral, rectal
2.0
8.9
121
345
M01AB05
ATC
diclofenac; systemic, rectal
1.6
8.8
289
1099
ZXD05
NOMESCO Finland
Urgent procedure
2.0
8.8
134
399
R52.9
ICD-10 Finland
Pain, unspecified
4.2
8.7
35
46
R51.80
ICD-10 Finland
Headache
2.5
8.6
71
159
K92.0
ICD-10 Finland
Haematemesis
6.6
8.6
24
20
N03AX16
ATC
pregabalin; oral
2.9
8.6
58
114
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.4
8.6
28
29
ZXE00
NOMESCO Finland
One hour or less
1.9
8.4
143
442
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.3
8.4
88
223
C07AB07
ATC
bisoprolol; oral
2.0
8.4
124
365
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
8.3
93
242
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
8.2
119
347
KH1AD
NOMESCO Finland
CT of urinary organs
9.9
8.1
18
10
R12
ICD-10 Finland
Heartburn
4.7
8.0
29
34
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
7.2
8.0
21
16
J01FF01
ATC
clindamycin; systemic
2.0
8.0
118
347
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
8.0
89
231
J01DB01
ATC
cefalexin; oral
1.5
7.9
432
1853
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
5.8
7.9
24
23
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.4
7.7
73
176
A06AC01
ATC
ispaghula (psylla seeds); oral
2.3
7.7
77
190
J01FA09
ATC
clarithromycin; systemic
1.8
7.7
139
440
N06AX11
ATC
mirtazapine; oral
1.9
7.6
117
349
N05AH04
ATC
quetiapine; oral
2.2
7.6
89
237
M03BC51
ATC
orphenadrine, combinations; systemic
2.1
7.6
94
256
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.6
7.5
268
1032
H02AB06
ATC
prednisolone; systemic
1.7
7.4
184
642
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
4.0
7.3
31
43
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
7.3
88
237
Z2221
NOMESCO Finland
Medical doctor
2.1
7.3
88
237
M01AC06
ATC
meloxicam; systemic, rectal
2.0
7.2
98
279
J01FA10
ATC
azithromycin; systemic
1.5
7.2
330
1349
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.3
7.2
71
174
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
7.2
248
947
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
7.1
270
1056
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.4
7.1
63
146
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
4.3
6.9
27
35
A02BA02
ATC
ranitidine; systemic
2.1
6.9
86
237
N06AX26
ATC
vortioxetine; oral
3.1
6.7
38
68
K50.9
ICD-10 Finland
Crohn disease, unspecified
9.2
6.6
15
9
A06AD11
ATC
lactulose; oral
1.9
6.6
102
305
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
6.6
168
590
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
6.5
67
169
J01DA01
ATC
[U] cefalexin; systemic
1.5
6.5
392
1692
N05BA12
ATC
alprazolam; oral
2.8
6.4
44
89
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.7
6.4
46
95
G04CA02
ATC
tamsulosin; oral
1.9
6.4
112
348
I10
ICD-10 Finland
Essential (primary) hypertension
1.9
6.4
109
337
K30
ICD-10 Finland
Functional dyspepsia
3.4
6.4
32
52
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
6.4
102
309
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
6.2
88
253
UKC02
NOMESCO Finland
Cystoscopy
2.3
6.2
60
147
D06
ICPC
Abdominal pain localized other
3.6
6.0
28
43
K85
ICD-10 Finland
Acute pancreatitis
15.0
6.0
11
*
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: R18_SYMPTOMS_SIGNS_INVOLVI_DIGES_SYSTEM_ABDOMEN – Symptoms and signs involving the digestive system and abdomen
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).