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Unspecified jaundice

R18_UNSPE_JAUND

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 R17
  • Cause of death: ICD-10 R17

2 out of 7 registries used, show all original rules.

2021

4. Check minimum number of events

None

2021

5. Include endpoints

None

2021

6. Filter based on genotype QC (FinnGen only)

2021

Control definitions (FinnGen only)

Control exclude
R18_SYMPTOMS_SIGNS_INVOLVI_DIGES_SYSTEM_ABDOMEN

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
R1
Name in latin
Icterus non specificatus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 2021 820 1201
Unadjusted period prevalence (%) 0.43 0.28 0.53
Median age at first event (years) 66.03 63.28 67.90

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1807
Matched controls
18068
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UJK02
NOMESCO Finland
ERCP
68.8
323.0
478
94
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
4503599627370496.0
323.0
1802
5
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
68.0
299.0
343
62
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
10.5
277.7
606
830
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
14.4
273.5
495
461
K83.1
ICD-10 Finland
Obstruction of bile duct
89.9
273.0
301
40
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
83.7
270.3
301
43
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
105.3
248.3
269
30
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
59.5
217.9
256
50
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
51.6
194.1
234
52
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
56.5
184.7
219
44
A09AA02
ATC
multienzymes (lipase, protease etc.)
36.1
177.8
231
73
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.0
177.5
494
917
K83.0
ICD-10 Finland
Cholangitis
47.2
170.4
209
50
JLC30
NOMESCO Finland
Pancreatoduodenectomy
161.3
167.7
175
12
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
23.0
163.6
241
120
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
45.5
152.3
188
46
130
Kela drug reimbursment
Malignant tumour
6.6
148.4
425
800
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
22.3
144.1
214
108
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.9
124.6
662
2351
JN3BD
NOMESCO Finland
Extensive abdominal CT
7.0
123.4
334
570
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
20.2
120.0
184
101
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
164.8
117.8
123
8
R10.1
ICD-10 Finland
Pain localized to upper abdomen
6.9
108.5
292
489
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
5.8
103.8
322
648
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
22.6
103.3
152
73
A03FA01
ATC
metoclopramide; systemic, rectal
3.7
99.8
523
1778
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
51.3
99.6
120
25
JN3AD
NOMESCO Finland
Abdominal CT examination
7.6
97.4
242
358
N02AA05
ATC
oxycodone; systemic
4.0
95.9
447
1367
K70.1
ICD-10 Finland
Alcoholic hepatitis
47.7
88.5
108
24
R18
ICD-10 Finland
Ascites
139.9
87.9
93
7
Z51.5
ICD-10 Finland
Palliative care
6.1
87.3
257
478
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
27.6
86.0
119
46
JN4CD
NOMESCO Finland
Very extensive body CT
8.2
83.4
196
264
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
23.5
80.8
117
53
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
9.7
80.7
171
193
R11
ICD-10 Finland
Nausea and vomiting
11.0
80.6
159
157
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
79.0
79.9
90
12
A05AA02
ATC
ursodeoxycholic acid; oral
25.3
79.1
112
47
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
124.2
77.6
83
7
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
7.6
77.3
191
277
JK3NB
NOMESCO Finland
Percutaneous transhepatic cholangiography
271.9
77.1
78
*
8140/3-C25.9
ICD-O-3
Adenocarcinoma, NOS, of pancreas, NOS
42.2
76.9
96
24
A02BC02
ATC
pantoprazole; systemic
2.5
72.8
1168
7656
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
20.8
71.8
108
55
JK4ZT
NOMESCO Finland
Percutaneous transhepatic implantation of bile duct prothesis
+∞
70.3
67
*
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
4.7
69.9
261
630
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
12.8
68.7
125
104
A04AA02
ATC
granisetron; systemic, transdermal
5.5
67.4
214
431
L01BC06
ATC
capecitabine; oral
7.7
65.1
158
222
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
24.2
64.2
92
40
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
66.1
60.8
70
11
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
10.0
60.2
124
132
WX302
NOMESCO Finland
Thoracal epidural anesthesy
6.0
59.6
174
315
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
6.8
58.3
154
244
JAH01
NOMESCO Finland
Laparoscopy
10.9
57.5
113
110
C24.9
ICD-10 Finland
Malignant neoplasm: Biliary tract, unspecified
83.0
57.3
64
8
TPH04
NOMESCO Finland
Cathetrisation of vein
2.8
57.1
455
1967
A06AD11
ATC
lactulose; oral
3.0
57.0
385
1498
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
23.2
54.0
78
35
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
26.5
53.3
74
29
N02AX02
ATC
tramadol; systemic, rectal
2.2
52.7
780
4617
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
50.1
52.4
63
13
8000/3-C25.9
ICD-O-3
Neoplasm, malignant of pancreas, NOS
24.8
52.3
74
31
K76.9
ICD-10 Finland
Liver disease, unspecified
15.4
52.1
87
59
JN4BD
NOMESCO Finland
Extensive body CT
3.4
52.1
287
961
J01MA12
ATC
levofloxacin; systemic
2.7
52.1
435
1919
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
50.7
823
5046
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
14.7
50.6
86
61
R50.9
ICD-10 Finland
Fever, unspecified
3.0
49.7
327
1240
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.2
49.6
288
1001
ZXD05
NOMESCO Finland
Urgent procedure
2.3
49.4
604
3244
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
36.2
49.1
63
18
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
23.4
48.7
70
31
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
6.0
48.0
138
244
H02AB02
ATC
dexamethasone; systemic
3.4
47.9
258
847
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
38.7
47.5
60
16
JKA20
NOMESCO Finland
Cholecystectomy
7.7
46.1
110
150
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
+∞
46.0
44
*
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
32.6
45.7
60
19
C03DA01
ATC
spironolactone; oral
3.0
45.5
292
1083
JK3FT
NOMESCO Finland
Exchange of bile duct catheter with radiological guidance
235.8
45.2
46
*
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
50.5
45.0
54
11
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.6
44.6
393
1769
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.3
43.3
173
439
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
18.3
43.0
67
38
K86.1
ICD-10 Finland
Other chronic pancreatitis
27.2
42.2
58
22
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.6
40.5
197
593
JN4AD
NOMESCO Finland
Body CT examination
3.5
39.3
200
624
D13
ICPC
Jaundice
139.7
38.9
41
*
K70.4
ICD-10 Finland
Alcoholic hepatic failure
43.8
38.3
47
11
JK3NT
NOMESCO Finland
Percutaneous transhepatic dilatation of bileducts
136.2
37.9
40
*
UJK12
NOMESCO Finland
Peroral cholangioscopy
56.3
37.5
44
8
C03CA01
ATC
furosemide; systemic
2.0
37.2
649
3952
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
21.0
37.1
55
27
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
36.5
478
2581
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
20.6
36.2
54
27
K85
ICD-10 Finland
Acute pancreatitis
10.5
36.0
71
70
ZX120
NOMESCO Finland
Intravenous
3.1
35.9
218
772
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.4
35.5
135
326
B01AB05
ATC
enoxaparin; parenteral
2.0
35.3
556
3237
K90.3
ICD-10 Finland
Pancreatic steatorrhoea
31.4
34.9
46
15
A04AA01
ATC
ondansetron; systemic, rectal
3.9
34.7
150
408
8140/3-C25.0
ICD-O-3
Adenocarcinoma, NOS, of head of pancreas
77.7
33.9
38
5
Z94.4
ICD-10 Finland
Liver transplant status
51.1
33.6
40
8
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
3.3
33.5
183
601
C24.0
ICD-10 Finland
Malignant neoplasm: Extrahepatic bile duct
332.9
33.0
33
*
WX002
NOMESCO Finland
Sedation and analgesia
2.2
32.7
381
1938
K72.9
ICD-10 Finland
Hepatic failure, unspecified
49.7
32.6
39
8
JAH00
NOMESCO Finland
Laparotomy
6.9
32.4
83
126
J01MA02
ATC
ciprofloxacin; systemic
1.9
32.4
694
4503
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.7
32.4
152
443
C24.1
ICD-10 Finland
Malignant neoplasm: Ampulla of Vater
73.6
31.9
36
5
WX402
NOMESCO Finland
General anaesthesia
2.5
31.8
286
1279
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
11.7
31.7
59
52
8000/3-C25.0
ICD-O-3
Neoplasm, malignant of head of pancreas
71.2
31.0
35
5
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
13.6
30.6
53
40
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.9
30.5
548
3319
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
30.4
337
1670
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
5.1
30.3
99
204
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
9.8
30.0
61
64
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.5
30.0
111
261
R4190
NOMESCO Finland
Nutritional therapy
5.3
29.8
94
186
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
26.2
29.7
41
16
TPX10
NOMESCO Finland
Implantation of vascular injection port
5.5
29.1
88
166
A10AE04
ATC
insulin glargine; parenteral
2.7
29.0
212
841
K80.4
ICD-10 Finland
Calculus of bile duct with cholecystitis
13.1
28.9
51
40
ZXE00
NOMESCO Finland
One hour or less
1.8
28.9
677
4478
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.4
28.7
107
253
UJF32
NOMESCO Finland
Coloscopy
2.1
28.7
399
2177
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
8.3
28.5
64
80
TPH07
NOMESCO Finland
Cathetrisation of artery
2.6
28.2
219
897
JJC00
NOMESCO Finland
Allogenic transplantation of liver
78.9
27.8
31
*
C24.00
ICD-10 Finland
Hepatic duct
285.7
27.8
28
*
K92.0
ICD-10 Finland
Haematemesis
5.8
27.5
80
144
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
19.9
27.4
41
21
C10AC01
ATC
colestyramine; oral
6.5
27.3
72
114
B01AB10
ATC
tinzaparin; parenteral
3.3
27.3
147
477
C24.02
ICD-10 Finland
Common bile duct
+∞
27.1
26
*
L04AX01
ATC
azathioprine; systemic
4.2
27.1
106
263
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.2
27.1
153
513
D76
ICPC
Malignant neoplasm pancreas
41.9
26.8
33
8
K75.4
ICD-10 Finland
Autoimmune hepatitis
98.2
26.7
29
*
JDE00
NOMESCO Finland
Gastrojejunostomy
29.7
26.3
35
12
K81.9
ICD-10 Finland
Cholecystitis, unspecified
10.5
26.1
51
50
K80.1
ICD-10 Finland
Calculus of gallbladder with other cholecystitis
6.2
25.9
71
119
C24.09
ICD-10 Finland
Biliary duct or passage NOS
264.2
25.8
26
*
R13
ICD-10 Finland
Dysphagia
7.7
25.7
60
80
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
25.4
25.3
35
14
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
6.5
25.2
66
104
K71.2
ICD-10 Finland
Toxic liver disease with acute hepatitis
58.9
25.0
29
5
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
32.5
24.7
32
10
WZC30
NOMESCO Finland
Teaching
2.4
24.3
234
1075
WW500
NOMESCO Finland
Blood transfusion
3.8
24.3
106
291
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
56.8
24.1
28
5
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
16.9
24.1
38
23
K70.9
ICD-10 Finland
Alcoholic liver disease, unspecified
31.5
23.7
31
10
WX004
NOMESCO Finland
Patient-controlled sedation
18.3
23.5
36
20
C25.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of pancreas
24.0
23.5
33
14
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
23.4
185
766
K80.8
ICD-10 Finland
Other cholelithiasis
9.5
23.3
48
52
K92.1
ICD-10 Finland
Melaena
3.2
23.1
126
412
P15
ICPC
Chronic alcohol abuse
5.6
23.1
68
125
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
5.8
22.8
65
115
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
15.9
22.4
36
23
H02AB06
ATC
prednisolone; systemic
1.7
22.2
756
5476
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
9.2
22.1
46
51
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
21.9
318
1747
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
21.5
595
4054
E80.4
ICD-10 Finland
Gilbert syndrome
26.8
21.4
29
11
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
+∞
20.9
20
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.8
20.9
71
154
A41.9
ICD-10 Finland
Sepsis, unspecified
3.6
20.6
94
268
127
Kela drug reimbursment
Transplant complication
7.6
20.5
48
65
F10.24
ICD-10 Finland
Alcohol depence active use
8.2
20.2
45
56
JK3SB
NOMESCO Finland
Endoscopic retrorade cholangiography
32.9
20.2
26
8
K86.3
ICD-10 Finland
Pseudocyst of pancreas
27.4
20.0
27
10
TJK01
NOMESCO Finland
Laparoscopic cholangiography
13.8
20.0
34
25
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
21.0
19.9
29
14
K81.0
ICD-10 Finland
Acute cholecystitis
6.1
19.7
54
91
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.0
19.7
81
212
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.9
19.4
119
422
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
19.4
302
1697
F10.25
ICD-10 Finland
Alcohol dependence continuous use
7.2
19.1
46
65
WX419
NOMESCO Finland
Other general anesthesy
9.2
18.9
39
43
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
18.8
237
1223
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.4
18.6
92
280
8000/3-C24.0
ICD-O-3
Neoplasm, malignant of extrahepatic bile duct
101.1
18.6
20
*
8160/3-C22.1
ICD-O-3
Cholangiocarcinoma of intrahepatic bile duct
38.8
18.6
23
6
R10.0
ICD-10 Finland
Acute abdomen
9.2
18.4
38
42
P01AB01
ATC
metronidazole; oral, rectal
1.7
18.3
509
3436
UJD02
NOMESCO Finland
Gastroscopy
3.5
18.0
84
245
8500/3-C25.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of pancreas, NOS
53.1
18.0
21
*
R4110
NOMESCO Finland
Physiotherapy
1.7
17.8
424
2732
N05CF01
ATC
zopiclone; oral
1.6
17.6
528
3636
F10.20
ICD-10 Finland
Alcohol dependence currently independent
5.7
17.4
50
90
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
17.3
615
4419
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
21.1
17.3
25
12
C25
ICD-10 Finland
Malignant neoplasm of pancreas
42.4
17.3
21
5
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
8.2
17.3
38
47
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
11.2
17.2
32
29
L04AA06
ATC
mycophenolic acid; systemic
6.2
17.2
46
76
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
12.7
17.1
30
24
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.1
16.9
66
165
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
3.2
16.9
89
285
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
15.2
16.7
27
18
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
16.7
248
1366
PHN73
NOMESCO Finland
Reconstruction of superior mesenteric or portal vein
90.9
16.6
18
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.8
16.5
109
405
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
16.5
279
1610
K70.0
ICD-10 Finland
Alcoholic fatty liver
10.9
16.5
31
29
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
16.4
428
2826
A41.8
ICD-10 Finland
Other specified sepsis
5.1
16.2
51
103
JJ5AT
NOMESCO Finland
NA
47.9
16.0
19
*
WX892
NOMESCO Finland
Monitored bed care
2.4
16.0
140
612
TJK00
NOMESCO Finland
Intraoperative cholangiography
9.6
15.9
32
34
103
Kela drug reimbursment
Diabetes, insulin-treated
1.6
15.8
491
3394
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
5.8
15.7
44
77
J01DB01
ATC
cefalexin; oral
1.5
15.7
1271
10947
JKB00
NOMESCO Finland
Incision of bile duct
33.7
15.7
20
6
SPAT1262
SPAT
Handing over of treatment supplies
1.8
15.7
318
1945
A02BC05
ATC
esomeprazole; systemic
1.6
15.6
546
3887
8500/3-C25.0
ICD-O-3
Infiltrating duct carcinoma, NOS, of head of pancreas
+∞
15.6
15
*
Z3226
NOMESCO Finland
Physiotherapist
1.8
15.6
295
1762
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
22.2
15.5
22
10
8000/3-C24.9
ICD-O-3
Neoplasm, malignant of billiary tract, NOS
161.3
15.5
16
*
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
8.6
15.5
33
39
N05BA04
ATC
oxazepam; oral
1.7
15.5
364
2326
Z2446
NOMESCO Finland
Social worker
2.6
15.5
118
479
RD210
NOMESCO Finland
NA
6.1
15.3
41
68
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.8
15.3
102
382
D64.9
ICD-10 Finland
Anaemia, unspecified
2.0
15.2
204
1079
WX882
NOMESCO Finland
High dependency care
3.6
15.1
68
193
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
3.8
15.1
64
173
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.3
15.0
75
232
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
10.1
14.9
29
29
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
9.2
14.7
30
33
8160/3-C24.0
ICD-O-3
Cholangiocarcinoma of extrahepatic bile duct
+∞
14.6
14
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
14.6
449
3087
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
36.3
14.4
18
5
8140/3-C24.1
ICD-O-3
Adenocarcinoma, NOS, of ampulla of Vater
36.3
14.4
18
5
D97
ICPC
Liver disease NOS
15.5
14.4
23
15
Z2221
NOMESCO Finland
Medical doctor
1.6
14.2
418
2835
K85.8
ICD-10 Finland
Other acute pancreatitis
13.5
14.2
24
18
N07BB01
ATC
disulfiram; oral
3.1
14.2
77
253
L04AD01
ATC
ciclosporin; systemic
4.9
14.1
45
93
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
17.7
13.8
21
12
B19.9
ICD-10 Finland
Unspecified viral hepatitis without hepatic coma
53.8
13.8
16
*
K76.7
ICD-10 Finland
Hepatorenal syndrome
53.8
13.8
16
*
A06AH03
ATC
naloxegol; oral
8.2
13.8
30
37
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.6
13.7
103
414
K71.0
ICD-10 Finland
Toxic liver disease with cholestasis
75.7
13.6
15
*
K86.01
ICD-10 Finland
Late effects of pancreatitis caused by alcohol
75.7
13.6
15
*
C23
ICD-10 Finland
Malignant neoplasm of gallbladder
34.3
13.5
17
5
C24.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of biliary tract
141.0
13.5
14
*
C07AA05
ATC
propranolol; systemic
1.8
13.4
253
1505
N06AX11
ATC
mirtazapine; oral
1.6
13.3
427
2956
C25.1
ICD-10 Finland
Malignant neoplasm: Body of pancreas
13.9
13.2
22
16
K86.9
ICD-10 Finland
Disease of pancreas, unspecified
15.2
13.1
21
14
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
3.2
13.1
69
223
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.1
13.0
153
763
TK800
NOMESCO Finland
Hemodialysis
4.3
13.0
48
115
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.8
12.9
81
294
JJA20
NOMESCO Finland
Open biopsy of liver
19.2
12.9
19
10
8140/3-C24.0
ICD-O-3
Adenocarcinoma, NOS, of extrahepatic bile duct
50.4
12.8
15
*
A07EA06
ATC
budesonide; oral, local oral
3.6
12.6
56
159
JL1AT
NOMESCO Finland
Biopsy of pancreas with ultrasound guidance
32.3
12.6
16
5
JLA00
NOMESCO Finland
Exploration of pancreas
130.9
12.4
13
*
WVA20
NOMESCO Finland
Medicine administration
4.0
12.4
48
121
JK3MB
NOMESCO Finland
Postoperative cholangiography
37.8
12.2
15
*
I81
ICD-10 Finland
Portal vein thrombosis
16.0
12.1
19
12
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
16.0
12.1
19
12
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
26.9
12.0
16
6
Z53.8
ICD-10 Finland
Procedure not carried out for other reasons
26.9
12.0
16
6
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.5
11.9
55
162
SPAT1255
SPAT
Intravenous administration of medicine
2.2
11.7
116
536
R94.5
ICD-10 Finland
Abnormal results of liver function studies
6.7
11.7
29
44
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
5.1
11.7
36
72
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.4
11.7
100
433
A02BC01
ATC
omeprazole; systemic
1.5
11.6
400
2806
T90
ICPC
Diabetes non-insulin dependent
1.6
11.6
366
2514
SPAT1254
SPAT
Administration of medicine
1.7
11.6
235
1429
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
9.3
11.5
23
25
ZXE60
NOMESCO Finland
More than 12 and less than 15 hours
6.8
11.4
28
42
TJA40
NOMESCO Finland
Percutaneous local drainage of peritoneal cavity
120.7
11.4
12
*
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
5.1
11.4
35
70
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.7
11.3
79
306
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
11.9
11.3
20
17
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
11.2
153
814
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
11.0
474
3485
JLW98
NOMESCO Finland
Other transluminal endoscopic operation on pancreas
43.6
10.9
13
*
A07AA11
ATC
rifaximin; oral
43.6
10.9
13
*
K71.9
ICD-10 Finland
Toxic liver disease, unspecified
43.6
10.9
13
*
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
6.0
10.9
29
49
A10AE05
ATC
insulin detemir; parenteral
2.3
10.8
97
430
TKC20
NOMESCO Finland
Catheterisation of bladder
2.1
10.7
128
646
B01AB04
ATC
dalteparin; parenteral
2.5
10.7
85
354
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
10.7
700
5585
K74.3
ICD-10 Finland
Primary biliary cirrhosis
13.0
10.6
18
14
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
8.0
10.6
23
29
UJF30
NOMESCO Finland
Ileoscopy through colon
2.1
10.6
122
606
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
8.5
10.5
22
26
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.1
10.5
115
561
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
4.1
10.4
39
96
JDH35
NOMESCO Finland
Endoscopic insertion of duodenal stent
+∞
10.4
10
*
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
2.9
10.4
61
214
E13
ICD-10 Finland
Other specified diabetes mellitus
32.7
10.3
13
*
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
8.2
10.3
22
27
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
5.5
10.3
29
53
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
9.6
10.3
20
21
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
4.2
10.2
38
93
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
10.1
378
2693
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
10.1
220
1367
K85.2
ICD-10 Finland
Alcohol-induced acute pancreatitis
14.7
10.0
16
11
A98
ICPC
Health maint/preventive medicine
0.7
10.0
1306
14275
K75.2
ICD-10 Finland
Nonspecific reactive hepatitis
40.3
10.0
12
*
Z3231
NOMESCO Finland
Registered nurse
1.5
9.9
412
3000
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
9.9
157
884
TJA10
NOMESCO Finland
Laparocentesis
26.2
9.8
13
5
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.6
9.7
70
279
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.5
9.7
75
308
K81.1
ICD-10 Finland
Chronic cholecystitis
11.4
9.6
17
15
R53
ICD-10 Finland
Malaise and fatigue
1.6
9.5
269
1788
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
5.2
9.5
28
54
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.1
9.5
110
546
B18.2
ICD-10 Finland
Chronic viral hepatitis C
6.6
9.4
23
35
K72.1
ICD-10 Finland
Chronic hepatic failure
100.5
9.4
10
*
WX610
NOMESCO Finland
Patient controlled analgesia
17.6
9.4
14
8
ZX121
NOMESCO Finland
Central venous catheter
17.6
9.4
14
8
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
6.2
9.4
24
39
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
12.4
9.4
16
13
D13.6
ICD-10 Finland
Benign neoplasm: Pancreas
8.1
9.3
20
25
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
6.9
9.3
22
32
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
9.2
197
1215
F10.09
ICD-10 Finland
Alcohol intoxication UNS
3.4
9.2
42
124
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
9.2
138
762
JEA00
NOMESCO Finland
Appendectomy
2.7
9.1
62
238
K70.2
ICD-10 Finland
Alcoholic fibrosis and sclerosis of liver
36.9
9.0
11
*
D01
ICPC
Abdominal pain/cramps general
2.1
9.0
100
493
JKB20
NOMESCO Finland
Intraoperative cholangioscopy
18.7
8.9
13
7
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
3.8
8.9
36
96
K31.5
ICD-10 Finland
Obstruction of duodenum
24.1
8.9
12
5
P16
ICPC
Acute alcohol abuse
4.5
8.8
30
68
K75.0
ICD-10 Finland
Abscess of liver
14.1
8.7
14
10
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
4.9
8.7
27
56
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
8.5
281
1938
GD1AD
NOMESCO Finland
Thorax CT examination
2.4
8.5
71
304
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.7
8.5
58
223
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
27.6
8.5
11
*
K29.2
ICD-10 Finland
Alcoholic gastritis
20.1
8.5
12
6
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
8.5
422
3176
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
8.4
200
1274
C24.01
ICD-10 Finland
Cystic duct
+∞
8.3
8
*
XW2BT
NOMESCO Finland
Other cytological test with X-ray guidance
+∞
8.3
8
*
D59.9
ICD-10 Finland
Acquired haemolytic anaemia, unspecified
10.8
8.3
15
14
D02
ICPC
Abdominal pain epigastric
2.6
8.3
58
229
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.1
8.1
89
437
C25.7
ICD-10 Finland
Malignant neoplasm: Other parts of pancreas
33.5
8.1
10
*
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
17.2
8.1
12
7
C10AA07
ATC
rosuvastatin; oral
0.6
8.0
172
2567
K29.3
ICD-10 Finland
Chronic superficial gastritis
2.8
8.0
49
179
3AC01
NOMESCO Finland
NA
5.3
8.0
23
44
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
8.0
213
1394
N03AX16
ATC
pregabalin; oral
1.5
8.0
290
2045
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
8.0
105
553
ZXE90
NOMESCO Finland
More than 22 hours
4.9
7.9
24
49
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.1
7.9
41
135
JL5CM
NOMESCO Finland
Bile and pancreas ducts extensive MRI examination with 3 Tesla magnet
45.2
7.7
9
*
JKD00
NOMESCO Finland
Anastomosis of gallbladder to jejunum
45.2
7.7
9
*
L03AA02
ATC
filgrastim; parenteral
2.8
7.7
49
181
K85.1
ICD-10 Finland
Biliary acute pancreatitis
6.4
7.7
19
30
K65.0
ICD-10 Finland
Acute peritonitis
5.3
7.7
22
42
N05BA01
ATC
diazepam; systemic, rectal
1.6
7.7
184
1173
K86.8
ICD-10 Finland
Other specified diseases of pancreas
18.4
7.6
11
6
JCA32
NOMESCO Finland
Endoscopic injection in oesophagus
18.4
7.6
11
6
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
11.9
7.6
13
11
K86.0
ICD-10 Finland
Alcohol-induced chronic pancreatitis
25.1
7.6
10
*
A04AA55
ATC
palonosetron, combinations; systemic
3.1
7.5
39
128
SPAT1265
SPAT
Breathalyser
5.8
7.5
20
35
XF600
NOMESCO Finland
Bloodpressure measurement
2.0
7.5
93
479
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
7.5
122
694
M04AA01
ATC
allopurinol; systemic
1.5
7.4
225
1521
JLB28
NOMESCO Finland
Endoscopic internal drainage of pancreatic duct
80.4
7.4
8
*
Q44.29
ICD-10 Finland
Atresia of bile ducts
80.4
7.4
8
*
N06AB04
ATC
citalopram; systemic
1.5
7.4
272
1922
C78.8
ICD-10 Finland
Secondary malignant neoplasm of other and unspecified digestive organs
13.4
7.4
12
9
E87.6
ICD-10 Finland
Hypokalaemia
2.7
7.4
48
182
SPAT1240
SPAT
Therapeutic discussion
1.9
7.4
102
546
SPAT1263
SPAT
Sampling
1.3
7.3
592
4816
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
7.3
331
2436
N17.8
ICD-10 Finland
Other acute renal failure
4.7
7.3
23
49
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.5
7.3
52
208
E14.8
ICD-10 Finland
Unspecified diabetes mellitus, with unspecified complications
10.9
7.3
13
12
E87.2
ICD-10 Finland
Acidosis
9.4
7.3
14
15
ZX122
NOMESCO Finland
Intra-arterial
9.4
7.3
14
15
K80
ICD-10 Finland
Cholelithiasis
4.9
7.3
22
45
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
7.2
115
650
N05BA06
ATC
lorazepam; systemic, sublingual
2.1
7.2
80
395
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
3.7
7.2
29
79
WX704
NOMESCO Finland
Intubation
1.9
7.1
95
505
K74.0
ICD-10 Finland
Hepatic fibrosis
20.1
7.1
10
5
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.0
7.1
38
128
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
6.6
7.1
17
26
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.5
7.1
221
1506
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
4.6
7.1
23
51
D98
ICPC
Cholecystitis/cholelithiasis
10.1
7.0
13
13
ZXK00
NOMESCO Finland
Conversion from percutaneous endoscopic to open procedure
6.3
6.9
17
27
L01BB02
ATC
mercaptopurine; oral
5.2
6.9
20
39
L03AA13
ATC
pegfilgrastim; parenteral
2.4
6.9
55
232
A10BA02
ATC
metformin; oral
1.4
6.9
436
3401
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.8
6.9
110
621
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
2.1
6.9
71
341
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
3.8
6.9
27
72
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
4.4
6.8
23
53
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
3.1
6.8
35
115
D77
ICPC
Malignant digestive neopl other/NOS
8.3
6.8
14
17
R73.9
ICD-10 Finland
Hyperglycaemia, unspecified
2.8
6.8
40
143
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
3.7
6.8
27
73
T89
ICPC
Diabetes insulin dependent
2.4
6.8
55
237
JKB21
NOMESCO Finland
Laparoscopic cholangioscopy
40.2
6.8
8
*
JK3AN
NOMESCO Finland
Biliary tract isotope imaging
40.2
6.8
8
*
JLD12
NOMESCO Finland
Endoscopic drainage of pancreatic pseudocyst
40.2
6.8
8
*
JLB12
NOMESCO Finland
Transduodenal endoscopic incision of pancreatic duct orifice
40.2
6.8
8
*
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
5.7
6.8
18
32
A04AD12
ATC
aprepitant; systemic
3.3
6.8
31
94
XJA00
NOMESCO Finland
Intraoperative abdominal ultrasonography
16.7
6.7
10
6
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.5
6.7
51
211
S18
ICPC
Laceration/cut
1.3
6.7
581
4762
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.8
6.7
106
597
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.1
6.7
74
366
E13.8
ICD-10 Finland
Other specified diabetes mellitus, with unspecified complications
12.3
6.6
11
9
B01AA03
ATC
warfarin; systemic
1.4
6.6
365
2788
D06
ICPC
Abdominal pain localized other
2.1
6.5
73
363
K35.9
ICD-10 Finland
Acute appendicitis, unspecified
2.2
6.5
61
281
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
3.3
6.5
30
92
Q44.21
ICD-10 Finland
Atresia of extrahepatic bile ducts
70.1
6.4
7
*
K70
ICD-10 Finland
Alcoholic liver disease
70.1
6.4
7
*
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
2.9
6.4
37
130
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.2
6.4
61
284
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.3
6.4
55
243
R60.0
ICD-10 Finland
Localized oedema
1.6
6.4
149
943
K29.7
ICD-10 Finland
Gastritis, unspecified
2.6
6.4
45
179
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
11.1
6.3
11
10
K51.5
ICD-10 Finland
Left sided colitis
2.9
6.3
36
125
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.1
6.3
69
342
8000/3-C22.1
ICD-O-3
Neoplasm, malignant of intrahepatic bile duct
+∞
6.3
6
*
JFA65
NOMESCO Finland
Endoscopic insertion of ileum stent
26.8
6.2
8
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
6.2
118
704
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
1.9
6.2
83
441
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.6
6.2
147
936
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.9
6.2
81
429
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
6.3
6.2
15
24
J01MA14
ATC
moxifloxacin; systemic
1.7
6.1
121
733
C07AB07
ATC
bisoprolol; oral
1.3
6.1
730
6237
K30
ICD-10 Finland
Functional dyspepsia
1.8
6.1
100
573
D11
ICPC
Diarrhoea
1.7
6.1
110
646
D70.82
ICD-10 Finland
Drug-induced neutropenia
3.6
6.1
25
70
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.5
6.1
44
179
JDA55
NOMESCO Finland
Endoscopic dilatation of stomach, pylorus or anastomosis of stomach
12.6
6.1
10
8
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
4.9
6.0
18
37
XX4BW
NOMESCO Finland
NA
10.1
6.0
11
11
XF612
NOMESCO Finland
Measurement of central venous pressure
10.1
6.0
11
11
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.1
6.0
60
285

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: R18_UNSPE_JAUND – Unspecified jaundice

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).