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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Flatulence and related conditions

R18_FLATU_RELATED_CONDI

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 R14
  • Cause of death: ICD-10 R14

2 out of 7 registries used, show all original rules.

384

4. Check minimum number of events

None

384

5. Include endpoints

None

384

6. Filter based on genotype QC (FinnGen only)

384

Control definitions (FinnGen only)

Control exclude
R18_SYMPTOMS_SIGNS_INVOLVI_DIGES_SYSTEM_ABDOMEN

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
R1
Name in latin
Flatulentia et condiciones cognatae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 384 223 161
Unadjusted period prevalence (%) 0.07 0.08 0.07
Median age at first event (years) 54.41 51.11 58.99

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
344
Matched controls
3440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R14
ICD-10 Finland
Flatulence and related conditions
+∞
323.0
344
10
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
19.5
110.2
188
200
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
8.9
70.0
188
408
R10.1
ICD-10 Finland
Pain localized to upper abdomen
11.9
48.1
94
105
UJF32
NOMESCO Finland
Coloscopy
6.3
44.1
143
351
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
8.2
39.1
95
152
K30
ICD-10 Finland
Functional dyspepsia
7.8
34.6
86
140
A06AC01
ATC
ispaghula (psylla seeds); oral
4.7
31.1
127
378
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
7.3
27.5
70
116
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
21.2
25.9
38
20
A02BC05
ATC
esomeprazole; systemic
3.4
24.2
165
731
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
+∞
23.2
22
*
R11
ICD-10 Finland
Nausea and vomiting
11.3
23.1
44
44
A02BC03
ATC
lansoprazole; oral
3.6
22.8
131
506
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
6.6
22.5
61
109
A02BC02
ATC
pantoprazole; systemic
3.0
19.8
232
1417
A02BC01
ATC
omeprazole; systemic
3.3
19.2
122
494
K59.09
ICD-10 Finland
Constipation, unspecified
9.6
19.0
39
45
D01
ICPC
Abdominal pain/cramps general
5.3
18.0
57
123
A02BA02
ATC
ranitidine; systemic
3.5
17.1
90
313
A03CA02
ATC
clidinium and psycholeptics; oral
7.7
17.0
40
58
R13
ICD-10 Finland
Dysphagia
17.4
16.8
26
16
R07.4
ICD-10 Finland
Chest pain, unspecified
3.1
16.4
109
447
A02BC04
ATC
rabeprazole; oral
4.8
13.7
47
110
R53
ICD-10 Finland
Malaise and fatigue
3.0
13.6
89
357
A03FA01
ATC
metoclopramide; systemic, rectal
3.1
13.5
85
331
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
6.7
13.4
34
55
M79.6
ICD-10 Finland
Pain in limb
2.5
13.2
130
663
J01MA02
ATC
ciprofloxacin; systemic
2.5
12.8
137
730
M54.5
ICD-10 Finland
Low back pain
2.6
12.6
117
575
A09AA02
ATC
multienzymes (lipase, protease etc.)
39.0
12.3
15
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.9
12.3
83
338
G44.2
ICD-10 Finland
Tension-type headache
3.8
11.6
51
151
R03AC02
ATC
salbutamol; inhalant
2.2
11.4
190
1232
R12
ICD-10 Finland
Heartburn
5.1
11.4
36
77
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
5.2
11.4
35
73
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
3.2
11.3
64
231
C10AC01
ATC
colestyramine; oral
13.3
11.3
19
15
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.2
11.0
156
933
N06AX21
ATC
duloxetine; oral
4.1
10.9
43
116
A03FA02
ATC
cisapride; oral, rectal
4.2
10.8
41
106
R10.2
ICD-10 Finland
Pelvic and perineal pain
61.9
10.7
12
*
N03AX16
ATC
pregabalin; oral
2.7
10.6
83
367
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.9
10.5
68
268
R06.0
ICD-10 Finland
Dyspnoea
2.5
10.5
95
454
J02AC01
ATC
fluconazole; systemic
2.2
10.4
137
788
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.3
10.1
53
181
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.7
10.0
76
330
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.1
10.0
163
1026
R15
ICD-10 Finland
Faecal incontinence
20.7
9.9
14
7
A06AD11
ATC
lactulose; oral
3.1
9.8
56
203
N05CF01
ATC
zopiclone; oral
2.3
9.8
116
633
R05
ICD-10 Finland
Cough
2.6
9.8
77
339
P01AB01
ATC
metronidazole; oral, rectal
2.2
9.7
127
725
H02AB06
ATC
prednisolone; systemic
2.1
9.7
165
1051
D06
ICPC
Abdominal pain localized other
4.9
9.7
31
68
A07AA02
ATC
nystatin; oral
5.2
9.5
29
60
N06AB04
ATC
citalopram; systemic
2.5
9.2
77
351
K59.1
ICD-10 Finland
Functional diarrhoea
5.2
9.0
27
55
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.8
9.0
59
234
J01DB01
ATC
cefalexin; oral
2.3
9.0
278
2237
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.2
8.9
33
84
R51.80
ICD-10 Finland
Headache
3.0
8.9
52
191
R07.3
ICD-10 Finland
Other chest pain
3.6
8.8
40
122
UKC02
NOMESCO Finland
Cystoscopy
2.7
8.7
61
252
J01EA01
ATC
trimethoprim; systemic
2.3
8.6
90
458
N05CF02
ATC
zolpidem; oral
2.6
8.6
66
288
N05BA01
ATC
diazepam; systemic, rectal
2.9
8.3
52
200
N06AX11
ATC
mirtazapine; oral
2.1
8.3
106
591
M03BX02
ATC
tizanidine; oral
1.9
8.2
198
1412
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.9
8.2
181
1249
R42
ICD-10 Finland
Dizziness and giddiness
2.4
8.2
75
355
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
9.3
8.1
16
18
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
9.3
8.1
16
18
J01AA02
ATC
doxycycline; systemic
2.0
8.0
258
2047
SPAT1263
SPAT
Sampling
2.0
7.9
145
931
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
7.8
44
157
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
7.8
69
324
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
7.8
101
563
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
46.0
7.7
9
*
L01
ICPC
Neck symptom/complaint
2.9
7.7
48
183
N30.0
ICD-10 Finland
Acute cystitis
2.8
7.7
51
202
UJF30
NOMESCO Finland
Ileoscopy through colon
3.5
7.6
35
109
L17
ICPC
Foot/toe symptom/complaint
2.2
7.5
87
460
N05BA12
ATC
alprazolam; oral
2.9
7.5
44
163
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.2
7.4
38
128
D02
ICPC
Abdominal pain epigastric
4.7
7.4
24
54
M54.2
ICD-10 Finland
Cervicalgia
4.2
7.4
27
69
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
3.7
7.3
31
90
K59.0
ICD-10 Finland
Constipation
4.1
7.2
27
70
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
6.8
7.2
17
26
D25
ICPC
Abdominal distension
8.2
7.2
15
19
JN3AD
NOMESCO Finland
Abdominal CT examination
3.9
7.2
28
76
N02AX02
ATC
tramadol; systemic, rectal
1.9
7.1
133
851
N06AB06
ATC
sertraline; oral
2.9
7.1
42
157
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.9
7.0
41
151
R52.2
ICD-10 Finland
Other chronic pain
6.1
7.0
18
31
SPAT1240
SPAT
Therapeutic discussion
2.9
6.9
43
163
R02
ICPC
Shortness of breath/dyspnoea
2.7
6.9
47
190
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.5
6.9
31
95
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
11.2
6.8
12
11
N03AX12
ATC
gabapentin; oral
2.5
6.8
53
232
Z00.0
ICD-10 Finland
General medical examination
2.2
6.8
73
374
C05AA08
ATC
fluocortolone; rectal, topical
2.6
6.8
52
224
K58
ICD-10 Finland
Irritable bowel syndrome
7.4
6.8
15
21
N05AH04
ATC
quetiapine; oral
2.4
6.8
57
258
M01AH01
ATC
celecoxib; oral (coxibs)
2.3
6.8
62
294
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
4.4
6.7
23
55
N06AX16
ATC
venlafaxine; oral
2.6
6.7
49
206
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
6.1
6.7
17
29
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
3.8
6.7
27
76
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
6.6
137
904
P01
ICPC
Feeling anxious/nervous/tense
2.9
6.6
41
155
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.5
6.5
53
236
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
71.1
6.4
7
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.8
6.4
40
153
M25.5
ICD-10 Finland
Pain in joint
2.0
6.3
90
518
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
9.5
6.3
12
13
N02BE01
ATC
paracetamol; systemic, rectal
2.0
6.3
276
2318
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
+∞
6.3
6
*
WX110
NOMESCO Finland
Local anesthesy
1.8
6.3
226
1773
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.5
6.3
49
214
SPAT1153
SPAT
Removal of sutures
1.9
6.2
105
644
SDA01
NOMESCO Finland
Simple parodonthologic therapy
2.0
6.2
92
534
L05
ICPC
Flank/axilla symptom/complaint
4.0
6.2
23
60
D11
ICPC
Diarrhoea
2.8
6.2
39
150
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.0
6.2
35
126
R10.0
ICD-10 Finland
Acute abdomen
8.8
6.1
12
14
R30.0
ICD-10 Finland
Dysuria
5.4
6.1
17
33
UJD02
NOMESCO Finland
Gastroscopy
4.7
6.1
19
42
SPAT1301
SPAT
No procedures
1.9
6.1
111
700
D07AC01
ATC
betamethasone; topical
1.9
6.0
108
675
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
3.1
6.0
31
106

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: R18_FLATU_RELATED_CONDI – Flatulence and related conditions

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).