Pain (limb, back, neck, head abdominally)

PAIN

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

247379

6. Filter based on genotype QC (FinnGen only)

247379

Control definitions (FinnGen only)

Control exclude
H7_EYEOTH

Extra metadata

First used in FinnGen datafreeze
DF3

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2145944 1235030 893797
Only index persons 1919106 1129012 790094
Unadjusted period prevalence (%)
Whole population 30.90 35.37 24.97
Only index persons 36.83 41.50 30.16
Median age at first event (years)
Whole population 42.51 42.31 42.83
Only index persons 41.37 41.11 41.75

-FinnGen-

Key figures

All Female Male
Number of individuals 247379 156824 90555
Unadjusted period prevalence (%) 48.50 53.46 39.92
Median age at first event (years) 46.01 42.28 52.48

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
6457
19260
1.77
314.93
7.5
7.3
104.4
104.6
mmol/l
3.86
6323
18830
22010
80808
1.61
307.65
3.1
2.6
122.2
125.0
ug/l
0.56
20509
75115
9032
28874
1.68
307.65
1.8
1.7
1161.9
1166.6
nmol/l
0.17
6982
21392
47537
215219
1.86
307.65
15.1
10.1
—
—
—
0
0
23832
83990
1.75
307.65
6.6
5.6
2.9
2.9
%
0.06
22295
78222
23943
84531
1.75
307.65
6.9
5.9
8.6
8.6
%
0.47
22504
79164
37552
135209
2.27
307.65
8.1
6.5
78.1
78.5
u/l
0.75
35635
126210
21915
73810
1.82
307.65
6.7
5.8
1.2
1.2
mmol/l
1.41
20028
66405
24526
87961
1.72
307.65
6.7
5.6
28.4
28.3
%
0.40
22934
81952
26428
91703
1.87
307.65
6.7
5.8
0.2
0.2
e9/l
0.38
23444
79641
40363
178600
1.52
307.65
5.7
5.0
39.6
39.2
mmol/mol
9.00
37678
165585
7544
18626
2.20
307.65
1.2
1.2
—
—
—
0
0
21447
83743
1.47
307.65
10.4
8.4
0.0
0.0
e9/l
0.84
17626
68209
6616
16327
2.17
307.65
3.1
2.7
7.8
9.7
umol/l
7.38
5752
14119
10153
28725
1.95
307.65
4.0
3.2
314.6
763.9
ng/l
13.97
7416
22272
7599
22163
1.83
307.65
2.2
1.9
—
—
—
0
0
42202
180186
1.78
307.65
4.9
4.1
2.0
2.2
mu/l
0.74
39245
164882
29269
101780
1.96
307.65
9.4
8.8
4.2
4.0
e9/l
10.28
25775
87868
32923
115551
2.09
307.65
4.8
3.5
992.1
1253.2
e6/l
0.47
408
1792
14423
46777
1.74
307.65
4.3
3.9
7.4
7.4
ph
0.44
2681
9327
13146
42492
1.73
307.65
7.3
6.8
—
—
—
0
0
8212
25622
1.71
307.65
3.8
3.6
0.8
0.8
mmol/l
3.28
7689
23914
13282
41833
1.78
307.65
4.6
3.6
90.2
89.5
%
2.00
12946
40766
10790
33118
1.79
307.65
1.5
1.4
2.3
2.4
g/l
1.46
6658
20630
23156
81153
1.75
307.65
6.6
5.7
0.7
0.7
%
0.04
21673
75613
9448
23946
2.18
307.65
1.3
1.2
28.4
39.3
iu/ml
4.00
2814
7642
17231
57254
1.74
307.65
3.5
3.0
34.4
34.1
u/l
0.08
16362
54230
7734
19868
2.11
307.65
1.4
1.3
496.9
565.4
titre
2.03
1479
3870
29242
101542
1.96
307.65
5.2
4.3
6.6
6.7
mmol/l
13.46
27471
92853
13219
43541
1.69
307.65
2.7
2.5
3445.6
5087.6
umol/l
4.83
11537
38270
48077
218623
1.89
307.65
11.5
8.2
27.6
26.8
u/l
8.83
46734
209838
19090
58811
1.97
307.65
3.9
3.0
83.4
72.6
ng/l
0.14
12380
38368
5678
11873
2.56
307.65
2.8
2.1
43.7
41.5
u/l
0.10
4896
10012
12940
43671
1.64
307.65
3.2
2.9
1439.4
1494.9
ng/l
0.56
10972
37196
16017
54003
1.69
307.65
2.6
2.1
—
—
—
0
0
46937
201542
2.24
307.65
18.3
12.4
139.6
139.7
mmol/l
24.27
46021
194845
5201
13621
2.01
307.65
2.2
2.3
362.6
384.8
nmol/l
11.23
4779
12605
11918
38593
1.70
307.65
3.8
3.0
—
—
—
0
0
19381
66843
1.70
307.65
3.6
2.8
5.8
5.8
ph
0.06
12
62
7512
18582
2.19
307.65
2.5
2.5
126.3
142.1
ug/g
2.69
5956
14666
47293
199171
2.48
307.65
16.7
10.3
22.8
24.7
mg/l
24.35
39098
148453
48171
216311
2.03
307.65
18.4
12.3
77.8
77.2
umol/l
3.62
48159
216164
10973
36786
1.62
307.65
1.6
1.5
19.9
20.2
nmol/l
1.15
9570
31523
10598
30088
1.95
307.65
3.0
2.5
550.1
559.4
mosm/kgh2o
3.30
9111
25196
14454
42462
1.96
307.65
3.4
2.8
—
—
—
0
0
18409
57984
1.89
307.65
4.0
3.2
79.9
113.9
e6/l
4.57
13492
38487
19921
71067
1.64
307.65
2.4
2.1
75.2
76.2
nmol/l
4.38
18175
64120
6613
19216
1.82
307.65
23.9
24.0
1.3
1.4
inr
4.03
1016
2406
32487
132846
1.56
307.65
3.5
2.6
49.2
44.4
u/l
15.88
30593
124568
34036
124429
1.99
307.65
4.7
3.5
—
—
—
0
0
8607
24583
1.90
307.65
3.1
2.7
2.5
2.4
e6/l
0.45
4759
12920
24464
87530
1.73
307.65
5.2
4.1
0.0
0.0
estimate
2.14
4783
16276
14818
43317
1.98
307.65
3.4
2.8
0.4
0.5
e6/l
5.06
11376
31313
47010
202376
2.23
307.65
18.4
12.5
4.0
4.0
mmol/l
0.34
46027
195236
12306
32003
2.20
307.65
1.9
1.7
1.1
1.3
mg/l
6.20
9198
24404
11494
31674
2.04
307.65
2.8
2.4
5.3
5.2
e6/l
0.43
10128
27252
19202
68112
1.64
307.65
2.0
1.8
95.2
95.8
pmol/l
0.92
10426
35635
15610
45886
1.99
307.65
2.3
2.0
200.8
243.8
u/l
4.30
14728
42853
2351
4280
2.83
307.65
1.1
1.0
—
—
—
0
0
9210
26024
1.93
307.65
2.9
2.5
1.1
1.2
e6/l
0.41
5336
14279
13294
46206
1.58
307.65
4.3
3.2
0.0
0.0
estimate
0.13
4622
15413
23206
84462
1.66
307.65
4.3
3.7
—
—
—
0
0
14650
46494
1.79
307.65
3.2
2.6
—
—
—
0
0
11135
37213
1.63
307.65
4.2
3.2
1.0
1.0
kg/l
0.41
1683
5781
26204
91654
1.84
307.65
6.5
5.5
2.0
1.9
e9/l
0.23
23297
79977
17883
44206
2.53
307.65
2.8
2.2
57.3
59.8
u/l
3.63
16673
40241
19964
64907
1.86
307.65
8.9
8.2
1.2
1.3
inr
3.07
5962
18709
16097
47858
1.97
307.65
3.5
2.9
79.5
115.5
e6/l
1.80
12595
35357
24479
87125
1.74
307.65
3.9
3.0
0.0
0.0
estimate
0.09
4647
15898
8985
21979
2.26
307.65
1.3
1.2
9.8
13.6
u/ml
3.65
3499
8787
15942
55563
1.62
307.65
3.3
3.4
2.3
2.4
mmol/l
4.98
13994
48550
18980
68324
1.60
307.65
4.1
3.1
—
—
—
0
0
31612
129644
1.53
307.65
3.8
3.3
—
—
—
0
0
24206
86439
1.73
307.65
6.5
5.4
56.8
57.0
%
1.73
22711
80935
21461
71205
1.84
307.65
5.3
4.5
35.7
35.7
g/l
0.43
20015
65731
13988
42701
1.86
307.65
4.6
3.9
—
—
—
0
0
36181
146698
1.71
307.65
4.1
3.5
14.7
14.7
pmol/l
1.06
33264
132804
12265
40651
1.66
307.65
2.5
2.1
—
—
—
0
0
25650
88408
1.86
307.65
6.4
5.5
0.0
0.0
e9/l
0.03
22373
75796
7889
24644
1.71
307.65
2.4
2.2
30.0
29.8
s
1.20
7650
23949
26975
82323
2.28
307.65
6.3
5.9
11.3
12.2
umol/l
16.85
25618
77428
17653
58701
1.75
307.65
6.5
5.7
—
—
—
0
0
12209
37870
1.79
307.65
1.3
1.3
1.7
2.0
u/ml
2.13
3269
10315
36328
131921
2.15
307.65
4.4
3.3
11.2
11.5
mm/h
2.14
33964
121260
24094
81970
1.85
307.65
7.4
6.3
1.2
1.2
mmol/l
0.99
20537
68200
12886
41112
1.75
307.65
2.4
2.1
2.9
2.9
mg/l
0.35
11126
34697
42746
191025
1.57
307.65
4.5
3.9
5.9
5.9
mmol/l
11.92
39450
174834
24709
88515
1.73
307.65
3.9
3.0
0.0
0.0
estimate
0.26
4656
15728
25513
88049
1.85
307.65
6.4
5.5
0.6
0.6
e9/l
1.06
22272
75474
6400
19181
1.76
306.59
1.9
1.6
—
—
—
0
0
8085
25893
1.66
305.51
2.6
2.4
13.2
13.5
umol/l
1.83
7510
23990
3932
10054
2.03
302.64
2.4
2.3
22.4
22.7
au/ml
0.04
205
706
5833
17209
1.78
293.59
1.4
1.4
—
—
—
0
0
3622
9083
2.07
292.99
1.3
1.2
52.6
50.2
au/ml
0.18
131
438
18826
73368
1.44
289.10
2.1
2.0
—
—
—
0
0
7468
23802
1.66
285.52
2.6
2.4
2.3
2.3
g/l
0.47
6919
21925
1774
3247
2.80
280.26
1.5
1.4
275.3
274.9
ug/g
0.02
1008
1896
4288
11638
1.92
278.73
2.7
2.6
10.4
10.8
g/l
4.69
3951
10655
8569
28450
1.60
278.38
3.0
3.0
2.4
2.4
mmol/l
1.04
7465
24681
4337
11857
1.90
275.84
3.6
3.1
—
—
—
0
0
11386
40550
1.51
271.47
4.7
4.1
—
—
—
0
0
13399
49370
1.48
271.11
3.5
2.7
—
—
—
0
0
4374
12131
1.88
266.12
2.4
2.1
6.1
9.0
ug/l
13.89
3795
10477
49990
235770
1.79
265.60
24.2
15.5
251.5
250.8
e9/l
1.51
49068
227909
4739
13543
1.83
262.69
7.4
7.7
1.3
1.4
mmol/l
0.80
4560
12973
6924
22142
1.65
259.16
2.7
2.5
22.8
23.4
%
2.14
5928
18918
50003
236065
1.78
259.07
24.0
15.4
30.2
30.2
pg
3.59
49495
231876
50004
236103
1.78
258.11
24.1
15.5
90.7
90.5
fl
12.35
49497
231890
50009
236137
1.78
258.01
24.1
15.5
4.5
4.6
e12/l
41.96
48966
227560
5045
14788
1.78
257.34
4.8
3.9
5.8
5.8
kpa
1.82
4907
14319
50017
236214
1.78
257.16
24.2
15.5
6.9
6.7
e9/l
46.31
48971
227631
5183
15335
1.77
256.22
4.8
3.9
7.4
7.4
ph
1.74
32
75
5020
14714
1.78
256.03
4.9
3.9
1.9
1.7
mmol/l
1.32
4118
11833
50015
236269
1.78
255.14
24.3
15.6
135.8
136.9
g/l
45.79
49502
232104
5794
17732
1.71
254.77
7.5
7.7
12.4
12.7
kpa
3.34
5532
16826
13030
48229
1.47
254.72
4.0
3.5
—
—
—
0
0
38572
172399
1.42
254.22
19.5
13.2
13.6
13.6
%
5.78
37939
167913
5795
17746
1.71
254.22
7.6
7.7
5.1
5.1
kpa
1.03
5534
16848
2284
5004
2.34
253.54
1.3
1.2
0.7
0.9
u/ml
0.37
220
362
6697
21355
1.65
252.91
6.8
6.0
1.0
1.1
mmol/l
0.45
6271
19897
5785
17766
1.71
250.99
7.6
7.7
1.0
0.9
mmol/l
0.77
4466
13748
10012
35423
1.51
242.14
1.7
1.6
36669064.5
29845285.2
pmol/l
0.51
8465
29392
5201
15724
1.73
237.73
8.0
8.2
95.7
95.6
%
0.50
5015
15072
2718
6705
2.09
227.66
2.3
2.3
6270.2
6278.9
u/l
0.00
1012
2988
3576
9757
1.90
226.99
1.2
1.2
—
—
—
0
0
4795
14477
1.72
219.21
8.3
8.6
122.6
121.8
g/l
1.50
4638
13893
4172
12129
1.78
216.78
4.3
3.4
4.7
4.7
kpa
0.00
4051
11690
4112
11929
1.79
215.10
2.6
2.4
66.5
66.4
g/l
0.27
3762
10854
4551
13639
1.73
213.20
9.2
8.8
—
—
—
0
0
3311
8987
1.90
212.98
1.3
1.2
—
—
—
0
0
1467
2819
2.65
211.62
1.4
1.2
—
—
—
0
0
6948
23309
1.57
210.24
1.7
1.6
—
—
—
0
0
4470
13418
1.73
207.97
1.2
1.1
—
—
—
0
0
14498
56621
1.39
201.27
3.4
3.2
7.9
8.2
mmol/l
0.57
12307
47951
4801
14853
1.68
200.01
2.5
2.3
0.2
0.2
g/l
0.43
4460
13797
3295
9183
1.85
195.15
1.9
1.8
1.3
1.3
g/l
0.88
3037
8399
5929
19566
1.58
190.94
1.5
1.4
—
—
—
0
0
43837
203771
1.40
184.01
4.8
4.3
2.7
2.8
mmol/l
24.52
40781
188830
3582
10429
1.77
184.00
1.3
1.3
212.9
312.9
u/ml
5.27
3327
9650
3329
9495
1.81
182.89
2.3
2.2
—
—
—
0
0
3731
11057
1.74
180.34
4.2
4.0
90.6
91.9
ng/l
0.28
3271
9559
4647
14752
1.63
174.20
8.3
7.5
9.4
9.8
mmol/l
2.18
4438
14016
2544
6749
1.93
173.96
3.5
3.0
1.3
1.2
%
4.94
2529
6717
3380
9832
1.77
173.79
4.9
4.9
—
—
—
0
0
1577
3464
2.32
173.19
1.5
1.4
494.3
561.1
mg/l
3.07
1497
3302
43148
200585
1.38
172.29
4.4
3.9
4.6
4.7
mmol/l
48.68
40402
186924
5522
18386
1.56
169.82
2.8
2.6
1.8
1.7
%
2.00
4915
16187
3175
9164
1.78
167.33
3.8
3.4
130.2
129.5
g/l
0.87
3103
8958
2479
6620
1.92
166.15
3.4
3.0
0.6
0.7
%
1.48
2373
6361
41446
191763
1.35
165.82
3.9
3.5
1.3
1.3
mmol/l
45.24
38401
177195
42802
199072
1.37
165.07
4.3
3.9
1.4
1.5
mmol/l
84.62
39889
184785
42188
195795
1.36
164.58
17.4
11.5
40.0
40.2
%
3.87
31292
148412
3230
9439
1.76
163.20
7.1
7.1
24.5
24.5
mmol/l
0.07
3023
8709
1632
3755
2.21
161.20
1.3
1.3
—
—
—
0
0
1401
3029
2.35
159.17
1.5
1.3
3.7
3.8
mmol/l
1.27
1312
2859
2025
5106
2.03
159.10
1.8
1.7
—
—
—
0
0
39422
181520
1.32
156.69
20.8
13.3
333.0
333.1
g/l
1.19
39136
179756
2802
7945
1.81
156.16
5.5
4.4
24.1
24.0
mmol/l
1.03
2516
7213
4044
12731
1.64
155.77
3.1
2.8
199.6
219.8
ng/l
1.70
3635
11624
2703
7647
1.81
151.62
2.5
2.3
—
—
—
0
0
1391
3067
2.31
151.33
1.6
1.5
3713.5
1383.2
e6/l
0.42
1130
2429
1389
3065
2.30
150.85
1.6
1.5
17.8
38.1
e6/l
1.94
1073
2316
3230
9674
1.72
149.47
9.5
10.2
93.8
93.9
%
0.50
3222
9635
1775
4388
2.06
146.75
1.7
1.6
1.2
1.2
g/l
2.71
1685
4182
1729
4239
2.08
146.02
1.7
1.6
0.2
0.2
g/l
0.11
1637
4025
10809
42001
1.36
145.97
2.0
1.9
—
—
—
0
0
13404
53896
1.33
143.99
4.1
4.0
10.8
9.0
mg/mmol
2.28
8716
34734
8932
33710
1.39
143.86
1.7
1.6
—
—
—
0
0
1747
4326
2.06
143.77
3.2
3.2
—
—
—
0
0
12800
51136
1.33
143.68
3.4
3.2
527.8
291.1
mg/l
5.45
8443
32456
3213
9717
1.70
143.41
9.4
9.9
1.4
1.3
%
3.21
3196
9648
3200
9688
1.70
142.24
9.5
10.1
0.7
0.7
%
1.62
3182
9628
1969
5128
1.96
141.36
2.3
2.3
378.3
707.5
ug/l
4.23
1840
4807
2762
8074
1.75
138.75
1.1
1.1
173.3
221.8
titre
0.55
60
286
2084
5608
1.90
136.08
1.7
1.7
—
—
—
0
0
2355
6604
1.82
135.53
1.6
1.6
10.9
15.5
u/ml
0.77
67
216
3568
11284
1.63
134.18
1.4
1.4
—
—
—
0
0
2336
6575
1.81
132.81
1.1
1.1
12.0
9.9
u/ml
0.07
33
108
4080
13366
1.57
132.71
2.7
2.6
70.9
68.6
e9/l
2.51
3091
9962
3412
10714
1.64
131.87
4.3
4.1
5.1
5.1
kpa
0.43
3164
9953
3365
10596
1.63
128.53
4.3
4.1
7.4
7.4
ph
1.51
397
1316
3349
10559
1.63
127.23
3.0
2.5
—
—
—
0
0
3353
10584
1.63
126.78
8.5
8.1
24.8
24.6
mmol/l
1.53
3332
10491
4250
14198
1.54
126.67
4.3
4.0
0.9
0.9
%
0.03
1189
3867
1523
3757
2.06
126.43
1.3
1.2
34.5
39.2
u/ml
0.25
79
253
1946
5246
1.89
126.26
2.2
2.1
7.4
7.3
g/l
0.60
1433
3875
1941
5230
1.89
126.11
2.2
2.1
3.8
3.9
g/l
1.83
1379
3698
1281
2959
2.20
125.14
1.6
1.5
—
—
—
0
0
1310
3060
2.17
124.60
1.6
1.6
14019.2
14838.3
e6/l
0.17
931
2230
2337
6739
1.77
122.60
1.9
1.7
—
—
—
0
0
4608
15790
1.50
121.98
4.5
3.8
—
—
—
0
0
2800
8525
1.68
121.37
10.2
10.4
—
—
—
0
0
2252
6468
1.78
119.66
1.9
2.0
39.0
39.6
u/l
0.64
2014
5712
5761
20716
1.44
119.57
7.6
6.0
—
—
—
0
0
3887
12886
1.55
119.54
4.0
3.8
0.6
0.7
%
0.85
863
2853
1026
2193
2.37
119.33
1.6
1.6
0.7
0.9
g/l
4.22
780
1634
1826
4910
1.89
119.29
2.3
2.2
3.0
3.1
g/l
0.41
1411
3808
4034
13549
1.53
116.93
4.3
4.0
0.1
0.1
%
0.12
1098
3618
1880
5143
1.86
116.58
1.6
1.6
298.5
295.9
titre
0.01
63
220
1730
4605
1.91
116.40
6.1
5.9
1.3
1.3
mmol/l
2.36
1525
4005
2731
8353
1.67
116.26
2.9
2.6
0.2
0.3
e6/l
1.33
2659
8127
2068
5849
1.80
115.48
5.1
4.9
—
—
—
0
0
1639
4299
1.94
115.05
1.2
1.1
—
—
—
0
0
1641
4327
1.93
113.45
1.2
1.1
—
—
—
0
0
1612
4231
1.94
112.92
1.3
1.2
767.2
1073.8
titre
1.00
50
116
1796
4905
1.86
111.89
2.2
2.1
10.2
10.5
g/l
1.90
1510
4091
4596
16020
1.48
111.46
4.0
4.3
19.3
28.5
ug/l
1.08
3695
12946
1396
3496
2.03
111.29
1.3
1.2
8.5
10.8
u/ml
0.51
202
560
1641
4359
1.91
111.04
1.3
1.2
83.0
130.0
titre
1.85
152
403
1422
3596
2.01
110.44
1.5
1.4
—
—
—
0
0
4362
15071
1.49
110.41
1.4
1.5
—
—
—
0
0
1835
5073
1.84
110.09
4.0
4.3
1.4
1.4
mmol/l
0.11
1813
4970
2445
7365
1.69
109.96
3.9
3.3
25.2
25.1
mmol/l
0.82
2366
7115
383
470
4.10
107.93
1.3
1.1
342.0
396.0
u/l
0.24
354
432
2146
6288
1.74
106.37
1.3
1.3
—
—
—
0
0
1168
2778
2.13
106.25
1.3
1.2
34.4
46.8
u/ml
1.28
97
258
3794
12835
1.52
105.95
4.4
4.1
0.1
0.3
%
0.48
918
3137
1367
3461
2.00
105.80
1.3
1.2
5.2
7.6
u/ml
0.40
132
362
3593
12045
1.53
104.56
2.7
2.8
4.1
4.1
e9/l
0.01
2811
9471
15209
64306
1.26
103.22
4.6
4.6
2.6
3.6
ug/l
3.93
13724
57761
6128
22828
1.39
103.13
1.3
1.3
—
—
—
0
0
1363
3481
1.99
103.01
3.2
2.7
—
—
—
0
0
414
588
3.55
96.85
1.4
1.5
6.1
6.5
u/l
0.31
360
502
2645
8407
1.61
96.53
9.9
10.1
24.2
24.2
mmol/l
0.02
2465
7848
1259
3203
1.99
96.14
2.2
1.9
—
—
—
0
0
4939
17931
1.42
95.90
1.4
1.4
—
—
—
0
0
2054
6157
1.70
93.77
5.5
5.0
0.9
0.9
%
0.89
1927
5733
1569
4341
1.83
93.76
4.2
4.6
3.9
3.9
mmol/l
1.61
1483
4051
1771
5097
1.77
93.14
3.6
3.5
2948.3
1041.0
u/ml
0.63
1530
4406
1008
2384
2.14
92.96
1.6
1.4
—
—
—
0
0
3102
10414
1.52
89.20
3.3
3.5
4.5
4.6
pmol/l
3.47
2747
9386
2068
6299
1.67
88.95
5.4
4.9
1.7
1.7
%
1.02
1940
5867
4301
15442
1.43
88.40
4.3
3.2
—
—
—
0
0
1480
4102
1.83
87.92
2.1
2.1
37.9
37.6
g/l
0.61
1286
3466
4376
15786
1.42
87.59
2.3
2.1
12.6
12.7
nmol/l
0.22
3856
14166
2287
7187
1.62
87.19
1.8
1.7
1.5
1.5
g/l
0.35
1959
6084
1115
2815
2.00
86.92
1.2
1.2
0.5
16.4
u/ml
—
10
40
2457
7901
1.58
85.24
3.5
3.0
—
—
—
0
0
1995
6097
1.66
84.69
3.6
2.6
—
—
—
0
0
2064
6388
1.64
83.48
2.7
2.2
21.5
21.6
s
0.22
1795
5612
3811
13517
1.44
83.40
4.1
3.7
1.2
1.2
mmol/l
1.42
3350
11733
11529
48198
1.25
82.50
1.7
1.6
1.4
1.3
mmol/l
14.11
9860
40767
706
1513
2.36
81.70
1.1
1.1
18.1
20.9
au/ml
—
6
13
1227
3283
1.89
81.14
1.5
1.3
—
—
—
0
0
855
2000
2.16
81.02
1.4
1.3
—
—
—
0
0
1948
6001
1.65
80.18
2.0
1.9
1.9
2.3
ug/l
0.71
1708
5256
1103
2858
1.95
80.03
1.3
1.2
2.7
7.4
u/ml
1.66
80
217
2428
7909
1.56
79.65
4.7
4.3
—
—
—
0
0
684
1468
2.35
78.92
1.1
1.1
62.6
53.8
au/ml
—
7
17
1478
4290
1.75
75.42
1.5
1.4
12.8
12.2
iu/ml
0.05
30
109
1183
3205
1.87
75.36
4.0
3.7
—
—
—
0
0
1602
4774
1.70
74.53
1.4
1.3
—
—
—
0
0
12041
51053
1.23
74.48
4.1
4.0
22.0
21.9
%
0.42
5362
24102
1261
3509
1.82
73.93
1.3
1.3
260.8
248.3
u/ml
0.76
809
2203
2238
7295
1.56
73.09
2.6
1.9
—
—
—
0
0
2141
6960
1.56
70.71
5.0
4.6
24.6
24.7
mmol/l
0.16
1978
6484
1855
5833
1.61
70.35
2.6
2.8
—
—
—
0
0
640
1408
2.29
69.99
1.4
1.4
—
—
—
0
0
656
1465
2.26
69.36
2.0
1.7
—
—
—
0
0
552
1141
2.44
69.00
1.2
1.1
38.4
48.4
mg/l
4.51
475
927
1776
5559
1.62
68.59
3.1
2.7
92.2
91.1
%
1.16
1662
5215
340
539
3.17
68.02
2.7
1.6
151.7
153.0
umol/l
0.02
189
247
636
1417
2.26
67.61
1.4
1.4
6.6
7.0
g/l
1.06
453
949
636
1417
2.26
67.61
1.4
1.4
2.8
3.0
g/l
1.11
456
952
635
1416
2.26
67.38
1.4
1.4
0.4
0.4
g/l
1.15
453
951
531
1094
2.45
66.84
1.1
1.1
253.8
279.0
mg/l
1.39
476
951
1187
3356
1.79
66.11
3.0
2.5
35.2
34.1
umol/l
0.45
1007
2850
1408
4199
1.70
65.29
2.0
2.0
11.5
10.8
mg/l
0.84
1308
3931
1555
4767
1.65
65.10
1.1
1.1
6.3
6.2
u/ml
0.05
183
742
3433
12479
1.40
65.03
1.2
1.2
140.3
152.1
iu/ml
0.75
1275
4742
1789
5707
1.59
63.93
3.4
3.4
0.4
0.3
g/l
0.50
843
2767
1355
4040
1.70
62.88
3.0
3.3
24.5
24.5
mmol/l
0.02
1188
3607
5652
22297
1.30
62.68
1.5
1.4
—
—
—
0
0
764
1897
2.03
62.33
1.2
1.3
0.2
0.2
nmol/l
0.04
31
130
887
2327
1.92
62.17
1.4
1.5
—
—
—
0
0
761
1889
2.03
62.13
6.9
6.2
11.4
11.2
mg/l
0.38
699
1735
2183
7338
1.51
61.93
1.7
1.6
299.9
313.9
mu/l
0.94
1989
6623
677
1610
2.12
61.69
1.5
1.5
—
—
—
0
0
1876
6138
1.55
60.14
1.4
1.4
8.6
8.7
u/l
0.18
1527
4943
1172
3408
1.74
59.41
7.3
6.8
11.2
11.3
mmol/l
0.16
1056
3036
1172
3409
1.74
59.35
7.3
6.8
105.2
105.2
mmol/l
0.00
1056
3037
1412
4328
1.65
59.13
4.5
3.7
7.4
7.4
ph
2.03
1193
3675
1051
2964
1.79
59.04
1.2
1.2
247.6
128.9
titre
0.45
21
70
2756
9795
1.43
59.02
2.5
1.8
—
—
—
0
0
2584
9081
1.45
58.75
2.5
1.9
—
—
—
0
0
2777
9897
1.43
58.58
2.5
1.8
—
—
—
0
0
1506
4713
1.62
58.15
1.2
1.1
—
—
—
0
0
2768
9874
1.43
58.08
2.3
1.8
—
—
—
0
0
753
1912
1.99
57.87
1.2
1.3
0.6
1.9
nmol/l
0.96
722
1852
1645
5289
1.58
56.84
3.4
2.8
3.5
3.6
g/l
2.52
1564
5068
1227
3662
1.69
56.74
3.7
3.5
—
—
—
0
0
653
1584
2.08
56.65
1.3
1.3
—
—
—
0
0
1260
3798
1.68
56.19
1.5
1.5
—
—
—
0
0
578
1341
2.17
56.00
1.5
1.3
1.4
1.4
promille
0.43
424
1071
2723
9751
1.42
55.89
2.4
1.8
—
—
—
0
0
1249
3768
1.68
55.53
1.5
1.5
24.9
22.1
u/ml
0.22
29
67
1873
6251
1.52
54.87
1.9
1.7
39.2
41.1
nmol/l
2.51
1824
6115
427
873
2.46
54.70
1.2
1.3
—
—
—
0
0
1453
4587
1.60
54.16
3.4
3.1
46.7
45.6
mg/l
0.04
1204
3650
1418
4465
1.61
53.41
3.3
3.0
3.1
4.1
ratio
0.33
130
335
1400
4404
1.61
52.94
5.0
4.6
8.6
8.5
kpa
0.69
1308
4145
1451
4605
1.59
52.93
3.4
3.1
96.0
65.0
mg/l
0.36
1198
3671
1629
5314
1.55
52.87
10.3
8.7
—
—
—
0
0
2154
7487
1.46
51.76
1.2
1.2
—
—
—
0
0
1337
4190
1.61
51.34
2.0
1.8
196.6
202.5
pmol/l
1.10
1259
4018
679
1736
1.97
51.26
1.2
1.3
—
—
—
0
0
982
2841
1.75
50.70
1.1
1.1
—
—
—
0
0
785
2121
1.87
50.50
1.7
1.6
—
—
—
0
0
484
1095
2.23
49.82
1.3
1.2
2.0
2.2
mmol/l
2.88
457
1010
462
1032
2.25
48.98
1.2
1.1
—
—
—
0
0
678
1764
1.94
48.76
1.3
1.2
58.7
56.4
u/ml
0.06
44
91
1214
3763
1.63
48.69
4.6
3.7
2.4
2.5
mmol/l
0.60
826
2517
1214
3764
1.63
48.64
4.6
3.8
5.0
5.0
kpa
0.72
1191
3672
1218
3783
1.63
48.47
4.6
3.8
8.8
8.6
kpa
1.30
1195
3690
563
1373
2.07
48.26
1.5
1.5
—
—
—
0
0
605
1522
2.00
47.78
3.3
3.1
16.3
5.6
nmol/l
0.61
586
1477
2418
8743
1.40
46.86
1.4
1.4
24.7
26.1
iu/l
1.22
2047
7435
1144
3535
1.63
46.46
1.5
1.5
108.6
111.0
u/ml
0.28
220
755
351
711
2.48
45.92
1.1
1.1
5.3
8.8
nmol/l
0.54
65
156
605
1547
1.97
45.72
1.5
1.5
23.2
39.5
iu/ml
2.12
25
71
886
2566
1.74
45.61
1.3
1.2
4.1
4.0
u/ml
0.07
399
1195
659
1739
1.91
45.53
1.6
1.6
56.2
58.8
%
0.81
420
1146
981
2928
1.69
45.41
1.1
1.1
—
—
—
0
0
2184
7816
1.42
44.84
3.3
3.3
54.8
49.1
u/ml
0.45
2093
7570
871
2528
1.74
44.52
1.2
1.2
—
—
—
0
0
1109
3439
1.63
44.43
3.5
3.1
—
—
—
0
0
397
872
2.29
43.79
3.1
2.2
—
—
—
0
0
661
1772
1.88
43.61
1.5
1.5
—
—
—
0
0
661
1772
1.88
43.61
1.5
1.5
—
—
—
0
0
661
1773
1.88
43.54
1.5
1.5
—
—
—
0
0
661
1773
1.88
43.54
1.5
1.5
—
—
—
0
0
5341
21834
1.25
43.35
1.7
1.8
—
—
—
0
0
849
2475
1.73
42.76
1.4
1.5
63.4
65.4
mmol/l
0.58
684
1940
13346
59547
1.16
42.14
1.5
1.5
—
—
—
0
0
500
1232
2.04
41.80
1.4
1.4
105045.9
87813.6
e6/l
0.22
343
830
833
2459
1.71
40.17
1.1
1.1
117.2
115.1
%
1.07
760
2230
259
482
2.70
39.93
2.4
1.9
9.3
9.5
mg/l
0.15
219
374
964
2968
1.64
39.76
2.7
2.9
—
—
—
0
0
1108
3539
1.58
39.40
2.5
2.4
16.6
16.6
%
0.01
567
1817
904
2748
1.66
39.15
1.1
1.1
14.6
11.7
au/ml
0.35
50
192
821
2432
1.70
39.11
2.3
2.4
7.7
7.2
umol/l
0.17
592
1811
923
2822
1.65
39.11
1.2
1.2
—
—
—
0
0
1821
6466
1.43
39.01
1.3
1.3
220.4
228.2
miu/ml
0.39
797
3096
947
2924
1.63
38.64
3.4
3.4
549.1
754.3
u/ml
0.29
872
2655
720
2068
1.75
38.21
1.6
1.6
—
—
—
0
0
318
684
2.34
36.83
1.2
1.3
71.6
63.4
%
0.74
37
91
557
1497
1.87
36.57
2.2
2.6
19.6
20.0
nmol/l
0.30
525
1431
820
2483
1.66
36.08
1.2
1.2
—
—
—
0
0
299
632
2.38
35.97
2.0
2.1
1.9
1.9
umol/l
0.23
288
604
757
2254
1.69
35.45
1.1
1.1
1.5
1.5
g/l
0.17
690
2048
626
1764
1.79
35.44
2.5
2.4
—
—
—
0
0
1289
4364
1.49
35.30
1.2
1.2
—
—
—
0
0
950
3006
1.59
35.17
1.6
1.6
—
—
—
0
0
840
2583
1.64
34.87
2.0
1.8
1.7
1.8
mmol/l
2.03
826
2511
1105
3631
1.54
34.78
1.7
1.6
—
—
—
0
0
5254
21940
1.22
34.52
4.3
4.1
31.6
32.3
%
4.00
3765
14920
472
1227
1.94
34.20
4.2
3.6
10.9
11.5
%
1.80
472
1227
696
2049
1.71
33.97
1.9
1.7
90.3
89.6
%
2.31
686
2013
265
545
2.44
33.79
1.1
1.1
438.1
694.5
ng/l
0.34
49
144
621
1772
1.76
33.76
2.4
2.3
—
—
—
0
0
280
599
2.35
32.88
1.1
1.1
—
—
—
0
0
476
1261
1.90
32.68
1.3
1.2
165.0
173.3
titre
0.03
12
46
476
1263
1.90
32.53
1.3
1.2
170.6
191.6
titre
0.24
95
222
467
1232
1.91
32.47
1.1
1.1
283.5
286.7
mg/l
0.36
427
1116
5757
24425
1.20
31.99
1.7
1.7
—
—
—
0
0
1214
4148
1.48
31.81
1.9
1.9
3.9
20.9
iu/l
0.73
426
1586
407
1034
1.98
31.50
1.2
1.2
35.8
49.2
u/ml
0.41
25
59
744
2280
1.64
31.35
2.8
3.1
758.0
747.6
u/ml
0.01
702
2152
1459
5182
1.42
31.23
5.9
4.2
1.5
1.4
mg/l
1.62
1359
4795
578
1653
1.76
31.23
2.7
2.4
1.3
1.1
e9/l
1.99
347
1014
1224
4211
1.47
31.00
1.1
1.1
1.5
2.0
u/ml
0.70
552
1833
221
434
2.56
30.95
1.1
1.1
—
—
—
0
0
481
1305
1.85
30.78
1.6
1.5
31.4
31.1
%
0.04
298
847
561
1599
1.77
30.67
3.6
3.4
—
—
—
0
0
447
1186
1.90
30.59
2.7
2.5
518.8
523.6
e6/l
0.07
367
965
1032
3438
1.51
30.56
3.4
2.8
1.6
1.7
mmol/l
1.97
1014
3364
204
391
2.62
29.94
2.0
1.6
103.6
126.9
au/ml
0.25
28
48
430
1144
1.89
29.22
2.7
2.6
0.2
0.2
e9/l
2.71
364
961
616
1834
1.69
28.96
2.5
2.1
105.4
105.6
mmol/l
0.45
611
1816
358
896
2.01
28.91
3.9
4.0
—
—
—
0
0
616
1836
1.69
28.85
2.5
2.1
4.1
4.1
mmol/l
0.71
611
1818
8477
37459
1.16
28.66
2.9
2.9
0.7
0.8
ug/l
7.50
5510
23589
820
2638
1.57
28.41
3.3
3.3
1.4
1.5
%
0.32
624
2085
1016
3433
1.49
28.16
1.5
1.4
137.2
137.8
pmol/l
0.01
985
3348
407
1078
1.90
28.05
2.7
2.0
—
—
—
0
0
257
574
2.25
27.54
2.9
2.9
128.6
146.3
au/ml
0.18
38
67
273
630
2.18
27.12
2.0
2.0
27.9
28.5
umol/l
0.38
268
610
541
1586
1.72
26.92
1.2
1.2
66.0
75.2
u/l
0.59
371
1058
600
1810
1.67
26.92
2.5
2.2
—
—
—
0
0
431
1181
1.83
26.83
1.1
1.1
—
—
—
0
0
1125
3918
1.45
26.81
2.2
2.1
130.9
131.0
g/l
0.02
825
2879
963
3255
1.49
26.68
3.6
2.9
7.4
7.8
mmol/l
2.19
947
3196
877
2907
1.52
26.64
3.6
3.4
—
—
—
0
0
305
745
2.06
26.33
2.1
2.4
22.9
70.3
umol/l
4.35
39
81
683
2144
1.60
26.26
1.5
1.6
57.6
62.9
mu/l
0.28
607
1930
533
1568
1.71
26.22
1.5
1.6
281.7
280.6
mosm/kgh2o
0.42
402
1239
868
2881
1.52
26.21
2.0
2.3
5.8
8.3
titre
0.43
22
102
474
1350
1.77
26.07
2.5
2.0
73.8
71.2
%
2.71
451
1299
4418
26087
0.83
25.61
1.3
1.3
—
—
—
0
0
1243
4456
1.41
25.32
1.1
1.1
—
—
—
0
0
287
696
2.07
25.26
2.8
2.2
10.6
12.9
%
1.74
272
645
799
2626
1.53
25.26
1.1
1.1
3.6
2.9
u/ml
0.48
356
1389
403
1104
1.83
25.15
1.1
1.1
—
—
—
0
0
294
721
2.05
25.14
1.2
1.1
3.6
4.4
iu/ml
0.43
22
63
297
733
2.04
24.99
1.6
1.6
22.8
26.0
umol/l
0.95
284
696
269
639
2.11
24.95
3.6
3.4
7.5
8.4
mg/l
1.38
210
509
402
1104
1.83
24.90
3.3
3.1
28.4
25.9
mu/l
0.42
381
1027
513
1517
1.70
24.81
3.1
3.4
58.2
58.1
%
0.02
321
997
637
1994
1.61
24.80
1.3
1.4
336.9
291.5
pmol/l
0.44
489
1548
1047
3660
1.44
24.50
1.1
1.1
1.3
1.1
u/ml
0.31
487
1657
471
1368
1.73
24.28
1.2
1.2
—
—
—
0
0
1087
3834
1.43
24.25
1.1
1.1
6.2
5.9
u/ml
0.14
603
2092
461
1332
1.74
24.20
2.5
2.0
13.1
13.4
%
0.18
259
634
776
2563
1.52
24.02
1.6
1.7
—
—
—
0
0
814
2720
1.51
23.87
1.5
1.4
—
—
—
0
0
277
678
2.05
23.84
2.1
1.7
—
—
—
0
0
3761
15755
1.21
23.57
1.4
1.4
—
—
—
0
0
433
1243
1.75
23.26
2.6
2.6
763.0
647.6
e6/l
1.68
157
460
106
161
3.30
22.99
2.5
2.8
—
—
—
0
0
2070
8153
1.28
22.55
1.1
1.1
—
—
—
0
0
288
732
1.98
22.45
26.1
27.3
115.1
123.8
ug/l
1.03
236
611
275
689
2.00
22.30
2.6
2.1
28.6
28.8
%
0.08
264
653
772
2594
1.50
22.10
1.4
1.3
22.4
25.5
u/l
1.79
632
2187
295
761
1.95
22.08
1.2
1.1
27.1
7.7
u/ml
0.78
32
84
1020
3623
1.42
21.94
1.1
1.1
2.1
2.6
u/ml
0.64
280
953
292
753
1.95
21.88
36.5
36.3
7.3
7.4
ug/l
0.24
274
681
552
1727
1.61
21.62
1.1
1.1
—
—
—
0
0
461
1377
1.68
21.58
1.6
1.5
—
—
—
0
0
272
688
1.99
21.52
2.1
2.3
175.7
268.9
ug/l
0.22
255
646
804
2741
1.48
21.46
5.1
5.1
359.7
376.8
umol/l
2.48
705
2367
304
801
1.91
21.43
1.5
1.5
7.0
7.6
ug/l
0.28
277
722
362
1013
1.80
21.22
1.2
1.2
1.1
1.1
ratio
0.03
121
384
195
436
2.25
21.00
1.1
1.3
18.7
22.3
%
0.23
25
78
417
1222
1.71
20.92
1.5
1.3
12.8
12.1
umol/l
0.98
400
1146
586
1879
1.57
20.75
2.0
1.9
24.0
29.0
mg/l
1.21
157
495
222
529
2.11
20.55
2.5
2.2
—
—
—
0
0
204
473
2.16
20.20
1.3
1.2
0.3
0.3
g/l
1.36
161
374
219
523
2.10
20.17
2.9
2.1
275.0
902.1
e6/l
0.72
131
273
211
500
2.12
19.82
1.2
1.2
0.2
0.2
g/l
0.06
15
30
260
669
1.95
19.67
1.5
1.7
3.7
7.6
nmol/l
0.55
206
570
473
1464
1.62
19.40
2.1
2.0
—
—
—
0
0
387
1136
1.71
19.35
1.8
1.8
4.1
3.9
mg/l
0.31
370
1079
707
2400
1.48
19.33
1.7
1.9
2452.5
3235.2
titre
0.32
32
125
755
2597
1.46
19.33
1.2
1.2
—
—
—
0
0
766
2643
1.46
19.30
1.3
1.3
38.8
35.8
u/l
0.19
688
2267
461
1420
1.63
19.28
1.3
1.3
1.5
1.4
nmol/l
1.01
416
1272
391
1154
1.70
19.18
1.5
1.4
—
—
—
0
0
197
461
2.14
19.11
2.4
1.9
81.5
60.4
ug/l
1.49
192
450
344
980
1.76
19.08
1.2
1.4
34.0
35.9
mmol/l
0.73
302
868
496
1569
1.59
18.66
2.0
1.7
1.0
45.4
mmol/l
—
5
10
560
1823
1.54
18.63
3.9
3.6
—
—
—
0
0
717
2462
1.47
18.54
1.1
1.0
0.8
0.4
u/ml
0.62
182
558
256
670
1.92
18.49
2.3
2.4
9.3
9.4
mmol/l
0.04
195
498
403
1216
1.67
18.27
1.1
1.1
—
—
—
0
0
255
673
1.90
17.99
1.6
1.5
4.9
4.0
%
0.37
67
163
1145
4292
1.34
17.88
4.5
3.3
—
—
—
0
0
203
497
2.05
17.63
1.2
1.2
—
—
—
0
0
230
592
1.95
17.46
2.5
2.9
—
—
—
0
0
269
731
1.85
17.41
2.5
2.5
54.4
53.8
umol/l
0.11
226
624
335
974
1.73
17.39
2.4
2.7
41.6
38.1
%
1.61
117
324
251
670
1.88
17.16
1.3
1.2
—
—
—
0
0
504
1642
1.54
16.77
1.2
1.1
—
—
—
0
0
852
3080
1.39
16.71
1.1
1.1
5.4
4.3
u/ml
0.68
360
1275
260
711
1.84
16.54
1.1
1.1
8.5
11.7
u/ml
0.58
54
130
381
1166
1.64
16.43
1.3
1.2
1.7
1.2
u/ml
0.34
159
465
215
553
1.95
16.39
1.1
1.1
—
—
—
0
0
115
226
2.55
16.36
1.7
1.3
—
—
—
0
0
793
2845
1.40
16.27
1.1
1.1
6.8
5.5
u/ml
0.57
346
1254
846
3075
1.38
16.08
1.1
1.1
10761.4
917.2
iu/ml
0.49
221
702
361
1096
1.65
16.07
1.1
1.1
9.0
7.1
iu/ml
0.65
79
307
494
1625
1.53
15.78
2.7
2.2
42.1
40.7
%
0.23
62
185
419
1330
1.58
15.64
1.8
1.8
6.4
6.7
mmol/l
1.07
312
955
286
825
1.74
15.33
2.9
2.4
7.4
7.4
ph
0.71
86
308
135
297
2.28
15.24
1.1
1.1
—
—
—
0
0
135
297
2.28
15.24
1.1
1.1
—
—
—
0
0
135
297
2.28
15.24
1.1
1.1
—
—
—
0
0
827
3023
1.38
15.23
1.5
1.5
0.4
0.4
nmol/l
0.13
646
2436
285
826
1.73
15.04
1.1
1.1
1542.4
1428.7
miu/ml
0.85
285
826
380
1190
1.60
15.02
1.6
1.4
64.6
74.4
umol/l
2.19
24
115
130
284
2.30
14.92
1.5
1.3
—
—
—
0
0
135
300
2.26
14.91
1.3
1.2
—
—
—
0
0
150
350
2.15
14.79
1.1
1.1
—
—
—
0
0
892
3319
1.35
14.71
1.1
1.1
—
—
—
0
0
412
1329
1.56
14.41
1.9
2.0
1.4
1.0
g/24h
0.47
28
82
889
3319
1.35
14.36
1.1
1.1
—
—
—
0
0
145
339
2.15
14.25
1.1
1.1
6.7
6.6
mg/g
0.02
139
322
196
515
1.91
14.14
3.0
3.0
28.0
29.0
umol/l
0.49
142
395
218
596
1.84
13.97
1.2
1.2
—
—
—
0
0
120
261
2.31
13.94
1.2
1.1
—
—
—
0
0
67
106
3.17
13.87
1.3
1.2
6.2
6.1
mmol/l
0.03
32
50
968
3680
1.32
13.86
2.2
1.9
0.9
0.8
nmol/l
3.34
813
3100
288
859
1.68
13.78
1.4
1.2
541.9
391.1
titre
0.24
21
79
360
1139
1.59
13.70
1.1
1.1
—
—
—
0
0
432
1426
1.52
13.67
1.2
1.1
361.7
373.8
nmol/l
0.50
374
1198
228
638
1.79
13.59
1.5
1.8
—
—
—
0
0
178
459
1.95
13.58
1.1
1.1
—
—
—
0
0
112
239
2.35
13.57
1.1
1.1
0.7
0.7
umol/24h
0.41
53
124
356
1126
1.59
13.57
11.5
12.5
0.6
0.6
mmol/l
2.24
334
1026
277
823
1.69
13.46
1.4
1.2
70.0
100.3
titre
0.52
26
69
339
1063
1.60
13.40
3.1
2.8
25.3
28.2
ug/l
—
6
13
614
2187
1.41
13.23
2.5
2.6
—
—
—
0
0
380
1229
1.55
13.19
1.2
1.2
—
—
—
0
0
631
2261
1.40
13.15
2.5
2.5
—
—
—
0
0
80
147
2.73
12.99
1.1
1.1
—
—
—
0
0
227
644
1.77
12.97
2.4
2.9
1.3
1.2
ug/l
0.37
213
606
67
111
3.03
12.95
1.1
1.1
—
—
—
0
0
239
691
1.74
12.81
1.6
1.6
5.7
5.6
mmol/24h
0.07
18
58
200
549
1.83
12.71
1.1
1.1
—
—
—
0
0
245
716
1.72
12.66
1.9
1.9
—
—
—
0
0
156
395
1.98
12.56
1.4
1.5
9.2
9.1
ug/l
0.08
156
395
518
1807
1.44
12.54
1.4
1.3
—
—
—
0
0
385
1265
1.53
12.49
1.1
1.1
—
—
—
0
0
152
382
2.00
12.49
1.2
1.2
38.7
40.5
g/l
0.66
83
206
279
849
1.65
12.45
1.7
1.5
1.3
1.3
nmol/l
0.06
213
678
258
770
1.68
12.38
5.0
6.1
944.5
2633.0
mg/l
0.81
190
551
116
263
2.21
12.33
3.3
6.8
106.9
42.8
u/l
0.79
35
124
23
14
8.23
12.27
1.7
1.4
267.6
153.3
nmol/l
—
18
9
115
264
2.18
11.90
1.9
1.9
—
—
—
0
0
144
362
2.00
11.85
1.1
1.1
—
—
—
0
0
66
115
2.88
11.79
1.1
1.4
—
—
—
0
0
552
1974
1.40
11.70
8.5
9.7
7.5
7.3
mmol/l
0.57
454
1608
73
136
2.69
11.62
1.3
1.2
120.3
211.1
titre
—
6
9
193
540
1.79
11.60
1.5
1.4
15.5
14.8
pmol/l
0.36
160
470
150
387
1.94
11.51
1.3
1.4
52.5
56.8
%
0.62
124
339
56
90
3.12
11.39
1.0
1.0
—
—
—
0
0
135
338
2.00
11.26
2.1
2.1
16.1
17.0
umol/l
0.41
135
338
110
254
2.17
11.25
1.2
1.2
82.5
60.1
mg/l
0.14
82
182
123
298
2.07
11.18
1.5
1.5
—
—
—
0
0
96
210
2.29
11.12
3.3
2.7
3017.7
838.2
u/l
1.06
85
186
353
1169
1.52
11.12
1.5
1.4
12.8
12.7
u/l
0.03
336
1135
94
204
2.31
11.08
1.9
1.9
37.4
51.7
pmol/l
0.76
77
180
771
2934
1.32
11.08
3.1
2.9
0.8
0.8
nmol/l
1.02
559
2259
72
137
2.63
11.05
1.1
1.3
—
—
—
0
0
149
390
1.92
11.00
1.3
1.3
16.9
17.0
umol/l
0.09
132
351
152
401
1.90
10.97
2.2
1.9
42.1
38.4
u/l
0.08
141
367
309
998
1.55
10.90
2.7
2.6
0.2
0.4
e9/l
0.67
296
969
57
96
2.98
10.80
1.1
1.1
31.7
47.9
u/ml
0.51
17
19
57
96
2.98
10.80
1.1
1.1
21.1
32.9
u/ml
0.56
14
16
1099
4399
1.26
10.70
2.4
2.4
130.3
103.0
ug/min
0.84
690
2685
250
772
1.63
10.63
3.0
2.8
—
—
—
0
0
139
360
1.94
10.60
2.3
2.1
—
—
—
0
0
582
2139
1.37
10.54
1.2
1.2
—
—
—
0
0
47
71
3.32
10.51
1.1
1.0
—
—
—
0
0
326
1077
1.52
10.42
1.0
1.0
—
—
—
0
0
152
411
1.86
10.23
1.7
1.6
—
—
—
0
0
2648
15154
0.87
10.08
1.4
1.4
—
—
—
0
0
285
921
1.55
10.07
1.2
1.1
—
—
—
0
0
251
788
1.60
10.02
1.5
1.6
—
—
—
0
0
62
115
2.70
10.01
2.4
2.6
3.1
3.3
mg/l
0.12
62
109
307
1012
1.52
9.94
1.2
1.2
—
—
—
0
0
246
775
1.59
9.70
2.1
2.1
170.9
98.7
ug/min
0.33
58
192
283
922
1.54
9.68
1.9
2.0
3.6
3.5
ug/l
0.06
242
821
137
365
1.88
9.67
1.3
1.3
121.3
127.7
nmol/l
0.16
102
267
45
70
3.22
9.67
1.2
1.1
—
—
—
0
0
120
306
1.97
9.61
1.3
1.4
119.2
70.8
mu/l
0.39
97
234
394
1378
1.44
9.55
1.2
1.1
—
—
—
0
0
265
854
1.56
9.51
1.2
1.2
—
—
—
0
0
456
1642
1.39
9.41
4.4
5.2
61.8
88.5
u/ml
0.66
133
528
101
244
2.08
9.34
1.3
1.4
30.2
227.9
titre
1.58
13
27
169
487
1.74
9.32
1.6
1.4
—
—
—
0
0
430
1541
1.40
9.13
3.0
3.0
72.1
58.1
mg/l
0.28
315
1117
266
868
1.54
9.07
3.4
2.5
—
—
—
0
0
81
181
2.24
9.04
1.0
1.0
0.1
0.3
u/ml
1.27
55
111
47
80
2.94
8.83
1.2
1.1
1.2
2.7
u/ml
—
7
9
186
560
1.67
8.81
1.0
1.0
12.5
13.6
u/ml
0.09
24
64
221
697
1.59
8.74
2.0
2.1
—
—
—
0
0
272
900
1.52
8.73
2.0
2.0
2.5
2.2
ug/l
0.44
230
759
138
382
1.81
8.72
1.4
1.2
40.6
37.7
%
0.33
85
269
51
92
2.78
8.70
1.1
1.3
—
—
—
0
0
53
98
2.71
8.66
1.1
1.1
4.3
4.6
u/ml
—
6
11
236
760
1.56
8.56
1.7
1.7
—
—
—
0
0
124
336
1.85
8.39
2.2
2.9
—
—
—
0
0
93
228
2.05
8.34
3.3
2.8
15.2
14.4
ml/dl
1.71
88
211
65
137
2.38
8.27
1.2
1.2
—
—
—
0
0
197
614
1.61
8.20
1.2
1.1
—
—
—
0
0
195
607
1.61
8.17
6.6
6.4
24.3
25.0
mmol/l
1.45
185
543
21
20
5.26
8.01
2.4
2.9
—
—
—
0
0
36
55
3.28
8.00
5.5
6.6
—
—
—
0
0
588
2262
1.31
7.98
1.6
1.4
31.7
33.6
g/l
2.62
516
2045
240
790
1.52
7.94
3.5
2.6
—
—
—
0
0
199
628
1.59
7.90
4.7
4.9
—
—
—
0
0
152
447
1.71
7.90
2.0
1.7
—
—
—
0
0
70
157
2.24
7.81
1.7
1.7
1.6
1.7
mg/l
0.27
63
128
136
389
1.75
7.78
1.3
1.2
—
—
—
0
0
528
2011
1.32
7.71
1.5
1.5
2705.0
3440.8
e6/l
0.49
373
1466
227
744
1.53
7.68
1.2
1.3
—
—
—
0
0
126
354
1.78
7.66
1.2
1.2
275.8
378.3
pmol/l
1.14
90
261
208
675
1.55
7.37
1.3
1.4
73.3
72.3
%
0.41
196
640
204
660
1.55
7.33
1.2
1.4
447.7
714.0
mu/l
1.46
192
625
707
2817
1.26
7.33
1.3
1.3
7.2
7.1
mmol/l
0.50
498
1987
146
436
1.68
7.22
1.4
1.4
—
—
—
0
0
86
217
1.99
7.21
1.5
1.7
—
—
—
0
0
52
106
2.46
7.14
1.4
1.2
91.6
87.6
umol/l
0.23
47
97
1046
4362
1.21
7.08
1.3
1.2
—
—
—
0
0
97
258
1.89
7.02
1.1
1.1
—
—
—
0
0
85
216
1.97
7.00
1.1
1.1
—
—
—
0
0
161
498
1.62
6.99
1.3
1.4
—
—
—
0
0
95
253
1.88
6.86
6.4
5.4
71.2
264.1
g/mol
0.51
82
236
188
607
1.55
6.85
1.1
1.1
4.8
14.7
u/ml
0.91
104
381
222
745
1.49
6.79
1.2
1.2
—
—
—
0
0
89
234
1.91
6.69
1.0
1.0
75.6
82.9
ug/l
0.92
71
193
76
189
2.02
6.66
1.2
1.2
50.7
53.0
%
0.13
37
90
112
318
1.77
6.64
1.4
1.3
26.0
26.7
g/l
0.15
83
256
367
1358
1.36
6.59
1.1
1.1
1.2
3.1
u/ml
1.40
133
416
244
842
1.45
6.52
2.2
2.2
2016.0
1987.7
ml
0.13
216
753
104
291
1.79
6.48
1.3
1.4
—
—
—
0
0
363
1348
1.35
6.38
1.1
1.1
4.4
7.7
u/ml
0.49
117
381
183
599
1.53
6.32
1.8
1.6
—
—
—
0
0
279
996
1.41
6.24
1.0
1.0
296.6
337.1
ng/l
1.48
190
725
280
1002
1.40
6.18
1.0
1.0
766.7
713.1
ng/l
1.10
185
696
204
689
1.49
6.11
2.3
2.0
7.6
9.2
%
1.01
193
672
68
168
2.03
6.10
1.5
1.6
106.4
120.0
ug/l
0.48
56
135
70
175
2.01
6.09
4.1
2.5
—
—
—
0
0
421
1612
1.31
6.04
1.4
1.3
6.4
6.2
mmol/l
1.14
388
1487
58
135
2.15
6.04
1.3
1.2
15.4
17.8
nmol/l
0.42
15
47
53
119
2.23
6.00
2.1
2.0
157.3
168.1
ug/g
0.17
47
101
81
215
1.89
5.97
1.4
1.4
387507.7
255255.6
nmol/l
0.16
64
181
79
208
1.90
5.96
1.0
1.1
0.1
1.5
u/ml
1.69
45
108
540
2140
1.27
5.96
2.1
1.9
21.1
24.8
ug/l
1.25
530
2098
125
381
1.65
5.83
1.7
1.7
0.8
0.3
mmol/l
0.65
115
357
465
1814
1.29
5.83
1.4
1.4
12.0
12.1
mmol/l
0.01
123
384
166
543
1.53
5.79
2.2
1.7
5579.0
1710.9
e6/l
0.38
115
367
59
141
2.10
5.78
1.2
1.2
—
—
—
0
0
22
30
3.67
5.76
1.1
1.7
—
—
—
0
0
131
406
1.62
5.74
1.2
1.2
500.0
620.0
titre
—
6
24
79
211
1.88
5.74
1.0
1.1
0.2
5.7
u/ml
1.20
39
114
102
296
1.73
5.69
1.9
2.7
8.1
7.3
mmol/l
0.57
69
158
149
478
1.56
5.67
1.9
1.7
9730.2
16781.7
e6/l
0.61
81
249
79
212
1.87
5.66
11.2
9.8
5.8
5.6
mmol/l
0.18
79
212
138
435
1.59
5.65
2.1
1.7
—
—
—
0
0
79
213
1.86
5.59
1.1
1.2
—
—
—
0
0
24
36
3.34
5.55
1.3
1.2
—
—
—
0
0
48
107
2.25
5.55
1.6
1.6
41.7
44.4
umol/l
0.29
48
107
467
1836
1.28
5.53
1.5
1.4
70343.6
56794.2
e6/l
0.32
275
1109
109
326
1.68
5.48
2.7
2.5
2.4
2.8
mmol/l
1.12
97
296
53
125
2.13
5.39
1.2
1.1
1.7
1.6
umol/24h
0.30
53
125
298
1105
1.35
5.38
1.6
1.6
2069.8
1973.4
ml
0.34
72
253
72
191
1.89
5.36
1.0
1.1
0.8
0.6
u/ml
0.17
45
102
447
1757
1.28
5.33
1.6
1.5
—
—
—
0
0
42
90
2.34
5.30
1.5
1.3
339.1
293.1
umol/24h
0.91
42
90
451
1779
1.27
5.23
1.6
1.5
—
—
—
0
0
404
1573
1.29
5.20
1.6
1.5
—
—
—
0
0
129
410
1.58
5.15
1.1
1.2
2.3
14.3
u/ml
3.35
94
299
212
749
1.42
5.12
10.0
10.9
—
—
—
0
0
118
368
1.61
5.10
1.2
1.2
—
—
—
0
0
118
368
1.61
5.10
1.2
1.2
—
—
—
0
0
127
404
1.58
5.06
1.1
1.1
0.9
2.9
u/ml
—
7
11
118
369
1.60
5.05
1.2
1.1
—
—
—
0
0
281
1046
1.35
4.98
1.3
1.4
5.7
5.6
mmol/l
0.65
261
996
193
674
1.44
4.97
2.3
1.9
—
—
—
0
0
184
638
1.45
4.93
1.1
1.1
—
—
—
0
0
319
1217
1.31
4.81
1.1
1.1
1.9
0.6
u/ml
0.44
58
182
89
262
1.70
4.80
2.0
2.2
1.5
1.6
mmol/l
0.13
62
192
55
139
1.98
4.74
1.2
1.2
—
—
—
0
0
187
656
1.43
4.73
1.0
1.0
—
—
—
0
0
40
89
2.25
4.70
1.2
1.1
—
—
—
0
0
29
55
2.64
4.68
1.6
1.5
—
—
—
0
0
39
86
2.27
4.67
1.3
1.5
35.7
39.4
%
0.17
25
65
73
205
1.78
4.63
1.0
1.0
—
—
—
0
0
91
274
1.66
4.55
1.3
1.2
—
—
—
0
0
15246
78761
0.96
4.41
2.7
2.6
—
—
—
0
0
21
34
3.09
4.40
1.0
1.2
—
—
—
0
0
67
187
1.80
4.35
1.0
1.0
—
—
—
0
0
74
213
1.74
4.35
1.7
1.6
—
—
—
0
0
44
106
2.08
4.32
1.2
1.1
26.9
21.9
%
0.20
15
26
2482
11383
1.10
4.31
1.7
1.6
—
—
—
0
0
64
177
1.81
4.29
1.3
1.2
623.4
58.3
u/l
0.64
47
125
72
207
1.74
4.26
3.4
3.4
43.1
41.3
umol/l
0.25
59
184
84
253
1.66
4.22
5.3
4.8
45.3
46.2
ug/min
0.04
65
201
43
104
2.07
4.19
2.4
2.0
—
—
—
0
0
32
68
2.36
4.18
1.5
1.7
1.5
1.7
mpas
0.63
19
42
116
383
1.52
4.03
1.5
1.3
14.0
13.3
g/l
0.30
92
294
52
138
1.89
3.97
1.1
1.2
—
—
—
0
0
257
982
1.31
3.92
1.7
1.8
2.6
2.9
u/field
0.24
182
709
17
26
3.28
3.89
1.2
1.3
2.3
2.0
mmol/24h
0.37
17
26
26
52
2.51
3.85
1.1
1.1
0.0
0.9
mg/l
0.51
21
46
75
226
1.66
3.80
12.5
10.7
0.3
0.4
umol/l
0.49
70
205
12
14
4.29
3.80
2.0
1.9
—
—
—
0
0
12
14
4.29
3.80
1.0
1.0
—
—
—
0
0
12
14
4.29
3.80
2.0
2.0
—
—
—
0
0
12
14
4.29
3.80
2.0
2.0
—
—
—
0
0
143
500
1.43
3.78
1.4
1.3
3.7
3.7
mmol/l
0.03
130
464
243
927
1.31
3.77
1.3
1.2
—
—
—
0
0
165
593
1.40
3.75
1.5
1.7
—
—
—
0
0
53
145
1.83
3.72
3.1
2.3
17.5
21.1
mmol/l
0.90
45
128
279
1087
1.29
3.71
6.2
7.1
—
—
—
0
0
37
89
2.08
3.69
1.6
1.3
22.3
16.7
pmol/l
0.44
32
74
74
225
1.65
3.65
1.1
1.1
1.6
9.3
u/ml
2.13
54
182
94
304
1.55
3.62
1.6
1.7
2.1
2.9
ug/l
0.45
43
193
96
312
1.54
3.62
2.7
2.4
62.6
44.0
mg/l
0.33
21
62
30
67
2.24
3.57
1.2
1.4
1.6
1.5
mg/l
0.19
25
57
33
77
2.15
3.56
1.2
1.2
1809.8
1294.8
u/l
0.11
28
71
66
196
1.69
3.56
2.8
2.6
80.6
80.5
pmol/l
0.00
61
173
44
115
1.92
3.55
1.3
1.7
—
—
—
0
0
42
108
1.95
3.54
1.0
1.0
6.7
23.5
u/ml
2.96
33
91
86
274
1.57
3.54
1.4
1.3
101.5
109.5
ng/l
0.07
56
176
33
78
2.12
3.46
1.3
1.5
14.1
10.7
%
0.29
23
58
56
160
1.75
3.45
5.1
4.6
2.5
2.2
mg/l
0.28
47
136
357
1448
1.24
3.43
2.1
2.0
1.9
2.4
u/field
0.98
157
605
431
1787
1.21
3.35
1.2
1.1
—
—
—
0
0
78
247
1.58
3.32
1.8
1.8
—
—
—
0
0
38
98
1.94
3.21
1.4
1.7
0.6
0.8
%
0.19
25
82
20
39
2.57
3.15
1.0
1.5
2.7
3.0
mmol/l
0.20
13
32
25
55
2.28
3.11
1.0
1.0
0.1
0.1
u/ml
0.00
11
15
28
65
2.16
3.09
1.3
1.4
0.7
1.8
%
0.81
18
44
165
616
1.34
3.05
1.5
1.3
64.0
60.5
%
0.59
133
502
31
76
2.04
3.01
1.7
1.5
—
—
—
0
0
240
946
1.27
3.00
1.4
1.5
—
—
—
0
0
1000
5604
0.89
2.99
1.5
1.4
—
—
—
0
0
436
1833
1.19
2.98
2.7
2.8
—
—
—
0
0
70
223
1.57
2.95
1.3
1.2
1.4
1.2
mmol/l
0.12
47
141
55
165
1.67
2.92
1.3
1.2
375.6
436.5
mg/24h
—
5
30
1004
5616
0.89
2.92
1.5
1.4
—
—
—
0
0
124
446
1.39
2.90
2.7
2.5
159.0
107.9
ng/l
0.88
76
267
29
71
2.05
2.84
1.1
1.3
0.6
1.3
umol/24h
0.58
13
32
34
89
1.91
2.80
1.0
1.0
0.1
0.7
u/ml
—
10
45
65
207
1.57
2.76
1.3
1.3
30.6
22.1
%
0.98
49
160
24
55
2.19
2.75
1.1
1.2
267.2
270.3
nmol/l
0.02
24
55
92
317
1.45
2.73
2.2
2.3
—
—
—
0
0
17
33
2.58
2.72
1.8
2.2
828.7
2127.9
umol/l
—
6
7
40
112
1.79
2.71
2.3
3.4
8.4
104.6
pmol/l
1.12
11
45
44
127
1.74
2.70
1.9
2.0
50.9
58.9
%
0.55
26
74
51
154
1.66
2.68
1.0
1.0
2.8
2.0
u/ml
0.16
33
103
423
1794
1.18
2.66
1.6
1.6
7.8
7.4
mmol/l
1.85
241
1026
1032
5729
0.90
2.65
1.5
1.5
—
—
—
0
0
114
412
1.39
2.63
7.5
7.1
—
—
—
0
0
75
250
1.50
2.63
2.2
2.3
3.0
4.0
ug/l
1.29
25
88
66
215
1.54
2.57
1.1
1.5
—
35.0
—
0
13
136
508
1.34
2.57
1.5
1.4
—
—
—
0
0
129
479
1.35
2.54
1.1
1.2
—
—
—
0
0
86
298
1.45
2.51
7.3
7.3
—
—
—
0
0
19
41
2.32
2.50
1.1
1.0
0.1
0.4
u/ml
0.35
11
22
12
20
3.01
2.47
1.1
1.1
—
—
—
0
0
84
291
1.45
2.47
1.2
1.2
1.6
1.7
mmol/l
0.15
52
176
51
158
1.62
2.46
1.2
1.1
—
—
—
0
0
77
263
1.47
2.43
4.2
1.4
7.7
7.5
mmol/l
0.09
20
90
50
155
1.62
2.41
1.0
1.1
3.2
11.8
u/ml
3.34
35
106
39
113
1.73
2.40
1.0
1.0
0.2
0.2
u/ml
0.22
13
47
60
195
1.54
2.39
1.0
1.1
—
—
—
0
0
50
156
1.61
2.36
1.3
1.2
—
—
—
0
0
674
2995
1.13
2.30
2.8
2.3
13.1
13.1
%
0.50
663
2952
15
30
2.51
2.30
1.7
1.1
—
—
—
0
0
585
3324
0.88
2.30
1.2
1.2
—
—
—
0
0
46
142
1.62
2.27
1.0
1.0
0.3
1.1
u/ml
2.87
22
111
122
461
1.33
2.19
1.9
1.8
—
—
—
0
0
10
16
3.13
2.19
1.0
1.0
—
—
—
0
0
27
72
1.88
2.17
1.3
1.1
—
—
—
0
0
50
160
1.57
2.16
4.9
2.7
6.5
7.6
%
0.15
22
40
18
41
2.20
2.14
1.0
1.1
0.2
0.2
g/l
1.31
13
34
124
472
1.32
2.13
7.2
7.5
—
—
—
0
0
19
45
2.12
2.08
1.3
1.1
—
—
mmol/l
—
0
0
9
14
3.22
2.07
1.0
1.1
—
—
—
0
0
105
392
1.34
2.07
1.4
1.4
25.8
23.1
%
0.40
87
325
15
32
2.35
2.05
1.4
1.2
—
—
—
0
0
30
85
1.77
2.02
1.4
1.1
1.0
1.2
u/field
0.65
21
59
293
1240
1.18
1.99
1.3
1.3
14.9
14.5
u/l
0.07
266
1158
439
1918
1.15
1.99
1.5
1.3
137.5
120.9
pmol/l
0.07
131
559
98
366
1.34
1.94
1.2
1.4
3.4
6.4
u/ml
0.44
23
88
31
90
1.73
1.94
14.5
8.2
138.6
298.3
e6/l
0.71
22
65
15
33
2.28
1.94
1.0
1.0
0.0
0.1
u/ml
—
10
25
351
1515
1.16
1.90
2.2
2.2
686.1
674.6
ml
0.18
241
1049
144
572
1.26
1.84
1.2
1.2
—
—
—
0
0
68
242
1.41
1.82
2.6
3.2
—
—
—
0
0
24
66
1.82
1.80
1.1
1.1
0.1
0.1
g/l
0.26
16
49
235
1397
0.84
1.79
1.1
1.0
—
—
—
0
0
45
150
1.50
1.69
1.1
1.1
16.2
17.2
g/l
0.30
36
135
20
53
1.89
1.68
1.1
1.1
0.1
0.1
u/ml
—
7
12
30
91
1.65
1.65
1.5
2.0
0.7
0.6
umol/l
0.36
22
73
192
1152
0.83
1.65
1.3
1.3
—
—
—
0
0
11
23
2.40
1.59
1.0
1.0
—
—
—
0
0
21
58
1.81
1.58
1.4
1.3
365.5
652.7
nmol/l
1.40
21
58
17
44
1.94
1.54
1.0
1.0
—
—
—
0
0
32
101
1.59
1.54
1.3
1.3
—
—
—
0
0
9
17
2.65
1.54
1.3
1.3
—
—
—
0
0
36
117
1.54
1.53
1.1
1.1
—
—
—
0
0
15
37
2.03
1.53
1.2
1.4
95.3
30.5
e6/l
—
10
27
20
55
1.82
1.53
1.0
1.1
—
—
—
0
0
18
48
1.88
1.51
1.0
1.1
5.8
5.3
mmol/l
0.17
12
33
64
237
1.35
1.42
1.6
1.6
—
—
—
0
0
16
42
1.91
1.41
3.5
5.6
4.1
5.6
mg/l
—
9
32
414
1853
1.12
1.40
1.2
1.2
—
—
—
0
0
23
69
1.67
1.36
1.0
1.0
—
—
—
0
0
36
121
1.49
1.35
1.1
1.1
—
—
—
0
0
13
32
2.04
1.35
1.5
3.2
3.4
1.8
mu/l
0.41
13
32
8
16
2.51
1.32
2.4
1.1
—
—
—
0
0
53
358
0.74
1.31
4.9
6.0
—
—
—
0
0
84
330
1.28
1.27
1.2
1.3
—
—
—
0
0
255
1115
1.15
1.27
2.2
2.1
499.2
500.1
min
0.05
188
847
69
264
1.31
1.27
1.6
1.3
6.8
12.6
%
1.97
37
136
35
119
1.47
1.26
1.0
1.1
0.9
2.3
u/ml
0.87
20
89
13
33
1.97
1.26
1.1
1.0
—
—
—
0
0
34
115
1.48
1.26
1.1
1.1
—
—
—
0
0
73
282
1.30
1.26
1.1
1.1
4.3
9.9
pmol/l
—
9
39
16
44
1.82
1.25
1.0
1.0
—
—
—
0
0
41
145
1.42
1.22
4.1
3.8
—
—
—
0
0
22
68
1.62
1.19
1.0
1.0
0.1
0.2
u/ml
0.27
11
33
52
193
1.35
1.18
1.5
1.4
68.5
71.8
%
0.32
44
163
11
27
2.04
1.16
1.2
1.2
—
—
—
0
0
11
27
2.04
1.16
1.3
1.5
4143.6
2054.0
umol/l
0.44
11
27
87
349
1.25
1.14
1.1
1.1
—
—
—
0
0
22
69
1.60
1.13
1.0
1.0
—
—
—
0
0
22
69
1.60
1.13
1.0
1.0
—
—
—
0
0
7
15
2.34
1.11
1.0
1.0
—
—
—
0
0
128
537
1.19
1.10
1.6
1.3
2.0
2.6
%
0.35
107
450
116
483
1.20
1.08
1.5
1.3
25.4
22.1
%
0.57
105
433
22
70
1.57
1.08
1.0
1.0
—
—
—
0
0
22
70
1.57
1.08
1.0
1.0
—
—
—
0
0
35
124
1.41
1.06
1.3
1.2
92.2
135.2
ug/l
0.95
20
73
917
4322
1.06
1.03
3.9
2.8
24.6
28.7
mg/l
2.92
577
2775
31
109
1.42
0.99
1.5
1.5
—
—
—
0
0
35
126
1.39
0.99
1.1
1.0
10.1
18.1
iu/ml
—
10
41
28
97
1.45
0.97
1.0
1.0
—
—
—
0
0
30
106
1.42
0.94
1.1
1.0
—
—
—
0
0
124
528
1.18
0.94
1.5
1.3
—
—
—
0
0
15
45
1.67
0.93
2.0
1.5
—
—
—
0
0
113
478
1.18
0.93
1.3
1.3
336.1
260.3
ug/l
0.12
54
263
20
65
1.54
0.93
5.2
5.8
0.8
1.2
mg/l
1.38
12
47
6
14
2.15
0.89
1.0
1.9
—
—
—
0
0
91
379
1.20
0.89
1.2
1.1
20.3
20.2
mmol/l
0.13
75
329
10
27
1.86
0.85
1.0
1.1
—
—
—
0
0
264
1462
0.90
0.85
1.3
1.3
1.5
1.5
g/l
0.24
19
68
15
47
1.60
0.81
1.0
1.0
0.1
0.1
u/ml
—
9
28
209
1166
0.90
0.79
1.6
1.4
—
—
—
0
0
5
11
2.28
0.78
1.0
1.0
—
—
—
0
0
9
26
1.73
0.77
1.2
1.0
—
—
—
0
0
11
32
1.72
0.77
1.0
1.2
—
—
—
0
0
27
98
1.38
0.77
1.0
1.1
—
—
—
0
0
23
81
1.42
0.77
1.0
1.0
0.1
0.9
u/ml
1.27
11
44
46
182
1.27
0.75
1.5
1.6
—
—
—
0
0
11
33
1.67
0.70
1.3
1.5
112.4
122.7
nmol/l
—
5
21
12
37
1.62
0.70
1.0
1.0
6.1
0.6
u/ml
—
5
18
7
21
1.67
0.67
1.0
1.3
—
—
—
0
0
7
21
1.67
0.67
1.0
1.3
—
—
—
0
0
16
54
1.48
0.66
1.1
1.2
—
—
—
0
0
772
4060
0.95
0.66
1.2
1.2
—
—
—
0
0
10
79
0.63
0.66
1.9
2.1
—
—
—
0
0
8
23
1.74
0.65
1.0
1.1
—
—
—
0
0
12
38
1.58
0.64
9.6
10.4
52.3
45.2
%
—
6
24
10
30
1.67
0.64
1.0
1.1
—
—
—
0
0
22
80
1.38
0.64
1.0
1.2
—
—
—
0
0
5
14
1.79
0.64
2.0
1.5
6.0
20.7
%
—
5
14
29
111
1.31
0.62
1.5
1.5
—
—
—
0
0
142
795
0.89
0.62
3.0
3.2
—
—
—
0
0
184
835
1.10
0.62
2.5
2.4
161.5
152.9
nmol/l
0.33
161
716
8
25
1.60
0.62
1.0
1.2
112.7
110.8
nmol/24h
—
8
25
8
25
1.60
0.62
1.1
1.0
125.1
147.6
mmol/24h
—
8
25
8
25
1.60
0.62
1.0
1.0
—
—
—
0
0
142
794
0.90
0.61
5.9
6.4
—
—
—
0
0
8
26
1.54
0.59
2.3
2.7
—
—
—
0
0
17
60
1.42
0.59
1.1
1.0
0.1
0.2
u/ml
—
8
29
1294
6707
0.97
0.58
1.4
1.4
—
—
—
0
0
24
91
1.32
0.56
1.1
1.0
—
—
—
0
0
49
204
1.20
0.55
2.5
2.7
—
—
—
0
0
13
44
1.48
0.55
1.5
1.2
—
—
—
0
0
552
2630
1.05
0.53
1.8
1.7
—
—
—
0
0
19
70
1.36
0.53
1.1
1.0
0.1
0.4
u/ml
—
8
32
38
155
1.23
0.53
1.1
1.0
—
—
—
0
0
7
22
1.59
0.50
1.0
1.1
1432.9
2164.1
titre
—
7
22
44
185
1.19
0.47
1.0
1.0
—
—
—
0
0
26
103
1.26
0.47
7.8
6.6
—
—
—
0
0
8
27
1.48
0.44
1.6
1.2
—
—
—
0
0
17
64
1.33
0.43
1.0
1.1
171.3
227.3
pmol/l
0.37
11
34
11
38
1.45
0.43
1.0
1.0
4.5
12.5
u/ml
—
6
32
0
9
0.00
0.43
0.0
1.1
—
—
—
0
0
676
3259
1.04
0.43
1.4
1.3
4.6
4.0
ug/l
0.38
607
2980
34
141
1.21
0.43
2.2
2.0
8.4
6.7
nmol/l
0.10
34
131
47
274
0.86
0.43
9.8
7.7
—
—
—
0
0
105
477
1.10
0.40
2.4
2.4
—
—
—
0
0
5
17
1.47
0.40
1.2
1.2
—
—
—
0
0
66
292
1.13
0.40
9.9
7.1
—
—
—
0
0
312
1647
0.95
0.38
20.0
19.3
1442.9
2902.5
nmol/l
0.74
299
1585
40
172
1.17
0.36
1.7
1.4
10.6
9.7
u/ml
0.04
34
143
40
173
1.16
0.34
1.3
1.4
0.2
0.2
umol/l
0.64
12
60
41
178
1.15
0.34
2.9
3.0
1.8
1.4
mg/l
0.30
30
119
12
45
1.34
0.32
5.3
5.9
0.3
0.2
mmol/l
0.40
12
45
9
35
1.29
0.27
1.1
1.4
—
—
—
0
0
1690
8330
1.02
0.26
1.5
1.4
—
—
—
0
0
14
86
0.82
0.25
1.1
1.1
—
—
—
0
0
7
48
0.73
0.23
1.0
1.1
—
49.4
—
0
5
7
48
0.73
0.23
5.7
7.3
—
—
—
0
0
0
6
0.00
0.22
0.0
1.0
—
—
—
0
0
21
92
1.14
0.18
1.0
1.1
—
—
—
0
0
22
97
1.14
0.17
3.3
2.4
—
—
—
0
0
8
34
1.18
0.17
1.4
1.2
—
—
—
0
0
825
4196
0.98
0.15
1.6
1.6
—
—
—
0
0
51
238
1.07
0.15
2.5
2.7
0.5
0.5
u/field
0.21
51
238
305
1562
0.98
0.13
13.7
13.5
831.7
1799.8
nmol/l
0.75
288
1519
563
2778
1.02
0.12
3.8
3.6
30.0
38.2
u/ml
1.22
543
2680
62
296
1.05
0.11
1.0
1.0
3.0
3.5
kpa
1.90
51
255
5
21
1.19
0.10
1.0
1.0
—
—
—
0
0
5
23
1.09
0.10
1.0
1.0
—
—
—
0
0
62
299
1.04
0.08
1.0
1.0
-1.6
-2.2
mmol/l
0.21
16
71
266
1312
1.02
0.07
1.4
1.4
31.6
32.6
nmol/l
0.23
232
1230
173
882
0.98
0.06
1.0
1.0
—
—
—
0
0
137
673
1.02
0.06
3.0
3.0
—
—
—
0
0
62
301
1.03
0.06
1.0
1.0
—
—
—
0
0
62
301
1.03
0.06
1.0
1.0
7.3
7.3
kpa
0.07
51
261
181
896
1.01
0.04
1.1
1.1
—
—
—
0
0
42
216
0.97
0.03
1.2
1.2
—
—
—
0
0
792
3980
1.00
0.02
1.3
1.3
—
—
—
0
0
16
78
1.03
0.00
1.0
1.0
—
—
—
0
0
71
358
0.99
0.00
1.0
1.0
8.2
8.9
mu/l
0.47
61
306
9
48
0.94
0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
8
43
0.93
0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint PAIN and mortality.

Females

Parameter HR [95% CI] p-value
PAIN 1.304 [1.21, 1.4] < 0.001
Birth year 0.989 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 117277 out of 929900 females with PAIN died.

Males

Parameter HR [95% CI] p-value
PAIN 1.519 [1.4, 1.64] < 0.001
Birth year 0.98 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 104850 out of 673910 males with PAIN died.

Mortality risk

Mortality risk for people of age

years, who have PAIN.

N-year risk Females Males
1 0.077% 0.183%
5 0.463% 1.067%
10 1.23% 2.711%
15 2.384% 5.121%
20 4.18% 8.871%

Relationships between endpoints

Index endpoint: PAIN – Pain (limb, back, neck, head abdominally)

GWS hits: 72

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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