No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
247379 |
6. Filter based on genotype QC (FinnGen only) |
247379 |
Control definitions (FinnGen only)
- Control exclude
- H7_EYEOTH
Extra metadata
- First used in FinnGen datafreeze
- DF3
Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 2145944 | 1235030 | 893797 |
Only index persons | 1919106 | 1129012 | 790094 |
Unadjusted period prevalence (%) | |||
Whole population | 30.90 | 35.37 | 24.97 |
Only index persons | 36.83 | 41.50 | 30.16 |
Median age at first event (years) | |||
Whole population | 42.51 | 42.31 | 42.83 |
Only index persons | 41.37 | 41.11 | 41.75 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 247379 | 156824 | 90555 |
Unadjusted period prevalence (%) | 48.50 | 53.46 | 39.92 |
Median age at first event (years) | 46.01 | 42.28 | 52.48 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint PAIN and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
PAIN | 1.304 [1.21, 1.4] | < 0.001 |
Birth year | 0.989 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 117277 out of 929900 females with PAIN died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
PAIN | 1.519 [1.4, 1.64] | < 0.001 |
Birth year | 0.98 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 104850 out of 673910 males with PAIN died.
Mortality risk
Mortality risk for people of age
years, who have PAIN.N-year risk | Females | Males |
---|---|---|
1 | 0.077% | 0.183% |
5 | 0.463% | 1.067% |
10 | 1.23% | 2.711% |
15 | 2.384% | 5.121% |
20 | 4.18% | 8.871% |
Relationships between endpoints
↥Index endpoint: PAIN – Pain (limb, back, neck, head abdominally)
GWS hits: 72