No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
8230 |
4. Check minimum number of eventsNone |
8230 |
5. Include endpointsNone |
8230 |
6. Filter based on genotype QC (FinnGen only) |
8230 |
Control definitions (FinnGen only)
- Control exclude
- PAIN
Extra metadata
- First used in FinnGen datafreeze
- DF3
- Parent code in ICD-10
- K07
- Name in latin
- Morbositates articulationis temporomandibularis
Similar endpoints
↥List of similar endpoints to Temporomandibular joint disorders based on the number of shared cases.
Similar with more cases:
- Dentofacial anomalies [including malocclusion]
- Temporomandibular joint disorders, including avohilmo
- Diseases of oral cavity, salivary glands and jaws
- Pain (limb, back, neck, head abdominally)
- Gastrointestinal diseases
Similar with less cases:
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 48348 | 36449 | 11702 |
Only index persons | 47066 | 35748 | 11318 |
Unadjusted period prevalence (%) | |||
Whole population | 0.87 | 1.04 | 0.33 |
Only index persons | 1.10 | 1.31 | 0.43 |
Median age at first event (years) | |||
Whole population | 42.71 | 42.82 | 42.47 |
Only index persons | 42.57 | 42.69 | 42.21 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 8230 | 6634 | 1596 |
Unadjusted period prevalence (%) | 1.96 | 2.26 | 0.70 |
Median age at first event (years) | 46.55 | 45.49 | 50.93 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 7348
- Matched controls
- 73480
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint TEMPOROMANDIB and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
TEMPOROMANDIB | 1.003 [0.9, 1.12] | 0.951 |
Birth year | 0.989 [0.98, 1.0] | 0.012 |
During the follow-up period (1.1.1998 — 31.12.2019), 1919 out of 32533 females with TEMPOROMANDIB died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
TEMPOROMANDIB | 1.079 [0.96, 1.21] | 0.189 |
Birth year | 0.985 [0.98, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 1020 out of 10470 males with TEMPOROMANDIB died.
Mortality risk
Mortality risk for people of age
years, who have TEMPOROMANDIB.N-year risk | Females | Males |
---|---|---|
1 | 0.09% | 0.22% |
5 | 0.468% | 1.274% |
10 | 1.261% | 2.946% |
15 | 2.44% | 5.698% |
20 | 4.142% | 9.8% |
Relationships between endpoints
↥Index endpoint: TEMPOROMANDIB – Temporomandibular joint disorders
GWS hits: 1