info icon

Benign neoplasm: Eye, unspecified

CD2_EYE_NOS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D31.9&
  • Hospital discharge: ICD-9 224[8-9]|2240
  • Hospital discharge: ICD-8 22409|22402
  • Cause of death: ICD-10 D31.9&
  • Cause of death: ICD-9 224[8-9]|2240
  • Cause of death: ICD-8 22409|22402

2 out of 7 registries used, show all original rules.

160

4. Check minimum number of events

None

160

5. Include endpoints

None

160

6. Filter based on genotype QC (FinnGen only)

158

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D31
Name in latin
Neoplasma benignum oculi non specificatum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 158 103 55
Unadjusted period prevalence (%) 0.03 0.04 0.03
Median age at first event (years) 57.28 55.50 60.60

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
160
Matched controls
1600
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D31.9
ICD-10 Finland
Benign neoplasm: Eye, unspecified
+∞
165.8
129
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
6.9
14.3
24
40
CBB30
NOMESCO Finland
Excision of lesion of eyelid
12.6
13.6
24
22
CBB99
NOMESCO Finland
Other excision or destruction of lesion of eyelid
128.9
11.6
12
*
2240A
ICD-9 Finland
Benign neoplasm of eye, Eyeball, except conjunctiva, cornea, retina and choroid
+∞
10.5
10
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.0
8.6
47
193
2248X
ICD-9 Finland
Benign neoplasm of eye, Other specified parts of eye
+∞
8.4
8
*
CD2S4
NOMESCO Finland
Photography of eye
47.3
7.8
9
*
CBA10
NOMESCO Finland
Biopsy of eyelid
26.5
7.7
10
*
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
26.5
7.7
10
*
3401
FHL
Removal of local modification or taking a specimen in the operating room
+∞
7.3
7
*
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
6.5
6.5
16
27
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
11.7
6.4
11
10

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
35
168
2.39
4.51
1.4
1.4
980.00
514.17
titre
—
8
48
7
14
5.17
2.76
1.3
1.1
—
—
—
0
0
80
601
1.66
2.56
14.4
10.4
0.00
0.00
e9/l
0.52
69
491
7
17
4.25
2.39
2.0
1.9
—
—
—
0
0
17
82
2.20
2.16
2.7
1.9
1.37
1.78
g/l
0.23
17
75
19
98
2.07
2.05
5.6
3.1
11.85
10.35
g/l
0.48
19
91
78
607
1.56
2.02
8.9
5.8
3.11
2.68
%
0.67
73
566
6
16
3.85
1.95
1.2
1.3
—
—
—
0
0
29
177
1.78
1.93
3.6
2.7
26.00
23.12
%
0.26
24
152
70
536
1.54
1.92
3.9
4.0
62.40
41.86
ng/l
0.24
38
378
5
12
4.26
1.83
1.4
2.2
41.10
28.83
%
—
5
12
7
23
3.13
1.82
5.3
2.6
—
—
—
0
0
8
29
2.85
1.82
1.8
1.7
—
—
—
0
0
16
82
2.06
1.77
1.5
1.6
—
—
—
0
0
6
18
3.42
1.76
2.2
1.7
11.05
208.91
u/ml
—
6
18
25
152
1.76
1.69
3.5
3.1
1.86
1.75
%
0.16
20
139
23
137
1.79
1.66
2.1
1.6
—
—
—
0
0
27
169
1.72
1.66
1.4
1.5
—
—
—
0
0
22
131
1.79
1.59
1.7
1.4
—
—
—
0
0
82
668
1.47
1.59
8.2
5.8
1.69
1.87
e9/l
0.97
77
601
5
15
3.40
1.53
2.2
1.7
34.20
31.87
pg
—
5
15
76
614
1.45
1.52
11.1
6.6
—
—
—
0
0
83
682
1.45
1.52
9.7
6.6
1.21
1.22
mmol/l
0.55
71
584
46
337
1.51
1.50
1.6
1.5
17.95
21.59
nmol/l
1.01
35
276
9
41
2.26
1.39
1.1
1.3
0.22
0.22
g/l
—
9
41
9
42
2.21
1.36
1.2
1.4
1.16
1.10
g/l
—
9
42
115
1017
1.46
1.35
3.8
4.1
15.17
14.93
pmol/l
0.48
101
913
79
655
1.41
1.32
8.2
5.8
0.04
0.04
e9/l
0.29
71
575
26
172
1.61
1.31
2.0
1.7
—
—
—
0
0
5
18
2.83
1.29
2.0
1.8
92.00
90.27
%
—
5
18
58
458
1.42
1.27
5.9
3.5
2.31
2.36
mmol/l
1.71
52
408
11
56
2.04
1.25
1.4
1.3
—
—
—
0
0
17
102
1.75
1.22
2.4
1.7
—
—
—
0
0
78
654
1.38
1.18
8.3
5.7
0.55
0.57
e9/l
0.43
70
576
5
21
2.42
1.10
1.8
1.2
—
—
—
0
0
5
21
2.42
1.10
1.2
1.2
—
—
—
0
0
7
32
2.24
1.09
2.0
1.6
—
—
—
0
0
38
285
1.44
1.09
3.6
3.1
565.90
520.54
mosm/kgh2o
0.57
31
255
10
53
1.95
1.04
1.1
1.1
—
—
—
0
0
89
776
1.33
0.99
16.2
9.9
3.36
4.00
e9/l
2.93
83
681
50
401
1.36
0.97
3.0
2.8
6.31
7.50
mmol/l
1.31
42
335
138
1291
1.50
0.97
4.4
4.7
5.92
5.94
mmol/l
0.05
125
1174
79
679
1.32
0.97
10.9
6.2
0.19
0.18
e9/l
0.38
72
604
8
43
1.90
0.89
1.3
1.0
—
—
—
0
0
6
30
2.04
0.88
4.7
7.2
—
—
—
0
0
46
374
1.32
0.81
3.2
2.9
1566.91
226.01
mg/l
0.40
27
240
24
175
1.44
0.80
1.1
1.2
—
—
—
0
0
32
246
1.38
0.80
4.2
3.6
629.65
94.94
ng/l
0.50
25
187
6
33
1.85
0.80
1.0
1.4
—
—
—
0
0
0
25
0.00
0.79
0.0
1.8
—
6.05
—
0
20
37
293
1.34
0.78
2.7
2.3
1.15
1.04
mg/l
0.14
28
228
27
203
1.40
0.77
2.4
1.8
—
—
—
0
0
15
100
1.55
0.76
4.3
4.9
0.00
0.23
%
—
7
30
14
92
1.57
0.75
3.5
5.7
440.00
290.88
ng/l
0.33
14
80
146
1396
1.52
0.74
21.4
17.0
83.55
76.21
umol/l
1.27
146
1396
48
398
1.29
0.73
3.9
3.6
1.97
8.74
mg/mmol
2.92
31
245
5
26
1.95
0.71
2.2
1.7
253.80
249.35
u/ml
—
5
17
14
95
1.52
0.66
4.0
4.9
0.33
0.38
%
—
6
29
7
44
1.62
0.66
1.9
1.5
—
—
—
0
0
62
538
1.25
0.65
2.6
2.1
—
—
—
0
0
63
548
1.25
0.65
2.3
1.9
89.42
95.14
pmol/l
0.41
34
279
5
29
1.75
0.64
1.0
1.4
—
—
—
0
0
8
51
1.60
0.61
5.5
4.3
0.95
0.86
%
—
8
51
0
20
0.00
0.61
0.0
2.0
—
—
—
0
0
0
20
0.00
0.61
0.0
2.0
—
—
—
0
0
0
20
0.00
0.61
0.0
1.3
—
—
—
0
0
15
106
1.46
0.60
1.1
1.1
—
—
—
0
0
6
35
1.74
0.58
1.0
1.4
—
—
—
0
0
109
1013
1.24
0.58
5.1
4.1
16.06
12.55
mm/h
1.21
103
918
6
36
1.69
0.57
1.0
1.4
—
—
—
0
0
6
36
1.69
0.57
1.0
1.4
—
—
—
0
0
6
36
1.69
0.57
1.0
1.4
—
—
—
0
0
70
623
1.22
0.57
9.2
5.6
1.21
1.22
mmol/l
0.60
63
566
17
125
1.40
0.56
11.5
3.9
1.89
2.36
mmol/l
0.24
11
99
14
99
1.45
0.56
3.6
2.7
—
—
—
0
0
11
74
1.52
0.55
1.4
1.2
—
—
—
0
0
17
126
1.39
0.54
3.5
4.4
—
—
—
0
0
15
109
1.42
0.53
4.3
4.7
0.86
1.03
%
—
7
39
33
273
1.26
0.51
1.8
1.4
2.27
2.62
g/l
0.20
22
166
130
1239
1.26
0.50
4.8
4.8
1.82
1.94
mu/l
0.69
120
1120
7
47
1.51
0.48
1.4
1.4
12.79
29.45
iu/l
—
7
41
32
377
0.81
0.45
4.6
4.0
0.00
0.00
estimate
-0.00
16
136
68
616
1.18
0.44
11.9
12.7
1.20
1.25
inr
0.21
21
181
100
936
1.18
0.43
4.0
3.9
—
—
—
0
0
5
32
1.58
0.42
4.8
2.7
—
—
—
0
0
13
97
1.37
0.41
4.2
5.0
0.00
0.07
%
—
5
27
0
19
0.00
0.39
0.0
3.3
—
3.42
—
0
19
8
112
0.70
0.38
1.5
1.5
—
—
—
0
0
8
115
0.68
0.38
3.3
3.7
—
—
—
0
0
42
370
1.18
0.37
5.5
4.0
—
—
—
0
0
13
100
1.33
0.35
15.2
5.4
—
—
—
0
0
40
353
1.18
0.34
17.4
8.1
—
—
—
0
0
24
202
1.22
0.33
3.1
3.0
0.79
0.71
ug/l
0.14
17
139
33
375
0.85
0.32
1.7
1.6
1.17
1.36
mmol/l
1.10
24
312
37
327
1.17
0.31
7.8
4.1
90.81
92.13
%
0.11
37
322
15
120
1.28
0.31
5.1
3.6
—
—
—
0
0
150
1470
1.33
0.31
29.9
21.2
38.79
39.85
%
1.04
141
1384
150
1470
1.33
0.31
29.7
21.4
4.38
4.44
e12/l
0.66
150
1427
150
1470
1.33
0.31
29.7
21.3
91.11
91.23
fl
0.10
150
1446
150
1470
1.33
0.31
29.6
21.3
30.23
30.33
pg
0.25
150
1446
19
158
1.23
0.30
1.2
1.3
—
—
—
0
0
150
1471
1.32
0.29
30.2
21.4
131.19
133.97
g/l
1.51
150
1445
150
1471
1.32
0.29
29.7
21.3
6.38
6.59
e9/l
0.79
150
1427
12
94
1.30
0.29
6.1
7.3
4.92
5.00
kpa
0.16
12
89
31
272
1.17
0.29
2.0
1.7
1003.84
1162.76
nmol/l
0.29
20
210
47
428
1.14
0.27
3.4
2.3
—
—
—
0
0
8
66
1.22
0.27
7.4
8.9
—
—
—
0
0
33
295
1.15
0.25
2.5
2.5
5.26
4.70
e6/l
0.11
26
274
25
219
1.17
0.24
2.5
3.0
2.00
2.77
e6/l
0.28
15
122
5
38
1.33
0.23
1.0
1.2
—
—
—
0
0
12
98
1.24
0.22
1.6
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
20.42
—
0
10
0
10
0.00
0.21
0.0
1.0
—
0.28
—
0
5
0
10
0.00
0.21
0.0
2.2
—
2.75
—
0
10
13
155
0.82
0.21
1.7
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
2.11
—
0
5
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
10
81
1.25
0.19
1.7
3.9
4.55
4.46
pmol/l
—
10
72
5
70
0.71
0.17
1.8
2.5
—
—
—
0
0
8
68
1.19
0.17
4.3
3.9
23.57
24.87
mmol/l
—
8
68
37
399
0.91
0.17
3.5
2.9
0.23
0.45
e6/l
0.62
27
300
137
1392
0.89
0.15
19.4
13.6
—
—
—
0
0
45
423
1.09
0.15
5.5
4.0
7.43
7.40
ph
—
9
82
41
385
1.09
0.14
3.3
2.8
—
—
—
0
0
17
152
1.13
0.13
1.4
1.2
—
—
—
0
0
70
676
1.06
0.11
6.2
5.3
0.00
0.00
estimate
-0.00
17
143
83
806
1.06
0.11
6.3
4.0
6.75
6.52
mmol/l
0.50
78
749
10
115
0.86
0.11
6.7
4.8
112.70
119.48
g/l
—
10
115
5
43
1.17
0.10
1.6
1.6
—
—
—
0
0
5
45
1.11
0.10
10.2
5.5
—
—
—
0
0
47
451
1.06
0.09
3.4
3.0
—
—
—
0
0
6
57
1.05
0.08
1.8
3.5
15.67
2574.80
u/ml
—
6
49
42
402
1.06
0.08
4.8
4.1
—
—
—
0
0
5
61
0.81
0.08
11.8
4.4
25.60
24.06
mmol/l
—
5
61
10
88
1.15
0.08
5.8
2.7
—
—
—
0
0
7
64
1.10
0.08
6.0
2.4
0.64
0.68
%
—
7
64
7
64
1.10
0.08
1.0
2.3
—
—
—
0
0
7
67
1.05
0.08
6.1
2.4
1.07
1.24
%
—
7
67
70
681
1.05
0.08
4.2
3.8
0.00
0.00
estimate
-0.00
18
147
40
383
1.06
0.08
4.8
3.5
—
—
—
0
0
8
78
1.03
0.07
7.1
4.1
—
—
—
0
0
37
354
1.06
0.07
3.5
2.9
356.77
7846.45
umol/l
1.98
31
304
45
434
1.05
0.07
3.1
3.1
20.05
213.24
e6/l
0.71
34
335
31
297
1.05
0.05
1.2
1.2
7.24
1.28
u/ml
—
8
84
30
288
1.05
0.05
2.0
1.8
403.72
476.44
pmol/l
0.78
25
241
19
201
0.94
0.05
2.3
2.0
—
—
—
0
0
130
1288
1.05
0.05
4.8
4.5
4.78
4.66
mmol/l
0.69
119
1193
52
507
1.04
0.04
3.6
3.7
7.61
62.11
e6/l
3.72
36
358
34
351
0.96
0.04
1.8
1.4
—
—
—
0
0
94
931
1.02
0.02
5.9
4.4
—
—
—
0
0
32
312
1.03
0.02
2.9
3.8
—
—
—
0
0
69
682
1.02
0.01
4.3
3.9
0.00
0.00
estimate
-0.00
17
132
22
227
0.96
0.01
1.2
1.3
46.53
7.63
u/ml
—
7
81
123
1237
0.98
0.01
6.3
5.6
40.21
39.82
mmol/mol
0.16
113
1152
10
106
0.94
0.01
1.4
1.4
—
—
—
0
0
14
141
0.99
0.00
1.4
1.7
—
—
—
0
0
24
244
0.98
0.00
1.2
1.2
17.44
30.26
iu/ml
1.02
14
85
134
1343
0.99
0.00
20.2
14.5
20.34
23.86
mg/l
0.60
109
1070
128
1283
0.99
0.00
4.7
4.5
1.49
1.49
mmol/l
0.03
114
1176
45
453
0.99
0.00
3.6
2.8
—
—
—
0
0
125
1245
1.02
0.00
4.3
4.0
1.32
1.30
mmol/l
0.14
111
1137
56
565
0.99
0.00
9.9
4.8
34.39
35.55
g/l
0.81
51
531
11
112
0.98
0.00
1.1
1.4
—
—
—
0
0
132
1318
1.01
0.00
5.4
5.1
2.88
2.73
mmol/l
1.08
121
1209
0
7
0.00
0.00
0.0
5.1
—
0.72
—
0
7
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
30.71
—
0
7
0
7
0.00
0.00
0.0
9.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
183.10
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
49
1.02
-0.00
1.8
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
119.00
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
1.20
—
0
5
7
72
0.97
-0.00
1.1
1.4
40.14
104.15
u/ml
—
7
62
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
7
79
0.88
-0.00
5.0
4.1
—
—
—
0
0
5
52
0.96
-0.00
1.2
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
91
0.99
-0.00
1.4
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
87.80
—
0
8
0
8
0.00
-0.00
0.0
1.1
—
159.33
—
0
8
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_EYE_NOS – Benign neoplasm: Eye, unspecified

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).