Inguinal hernia, bilateral

HERING_BILATERAL

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

4470

4. Check minimum number of events

None

4470

5. Include endpoints

None

4470

6. Filter based on genotype QC (FinnGen only)

4339

Control definitions (FinnGen only)

Control exclude
K11_HERNIA

Extra metadata

First used in FinnGen datafreeze
DF3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 32945 3598 29171
Only index persons 30071 3207 26864
Unadjusted period prevalence (%)
Whole population 0.73 0.10 0.82
Only index persons 0.93 0.12 1.03
Median age at first event (years)
Whole population 60.00 58.80 60.10
Only index persons 59.60 58.64 59.71

-FinnGen-

Key figures

All Female Male
Number of individuals 4339 465 3874
Unadjusted period prevalence (%) 1.60 0.16 1.77
Median age at first event (years) 62.78 58.99 63.24

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
4470
Matched controls
44697
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D89
ICPC
Inguinal hernia
41.5
307.7
317
82
JAB11
NOMESCO Finland
Laparoscopic repair of inguinal hernia
1087.2
307.7
1308
17
JAB30
NOMESCO Finland
Repair of inguinal hernia using prosthetic material
1294.3
307.7
1962
27
K40.3
ICD-10 Finland
Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
109.0
307.7
257
25
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
21.1
307.7
265
133
ZXA10
NOMESCO Finland
Bilateral
3.7
307.7
1371
4728
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
36.4
307.7
222
64
K40
ICD-10 Finland
Inguinal hernia
33.8
307.7
438
143
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
56.5
307.7
359
69
K40.0
ICD-10 Finland
Bilateral inguinal hernia, with obstruction, without gangrene
1864.5
307.7
483
*
K40.2
ICD-10 Finland
Bilateral inguinal hernia, without obstruction or gangrene
10132.5
307.7
3957
34
6123
FHL
Radical surgery
113.6
307.7
206
19
JAB12
NOMESCO Finland
Laparoscopic repair of inguinal hernia, TEP
+∞
307.7
576
*
K40.9
ICD-10 Finland
Unilateral or unspecified inguinal hernia, without obstruction or gangrene
173.6
307.7
2190
246
JAF10
NOMESCO Finland
Repair of umbilical hernia
24.8
245.5
174
73
55099
ICD-8 Finland
Inguinal hernia without mention of obstruction
+∞
197.4
188
*
JAB10
NOMESCO Finland
Repair of inguinal hernia
334.5
193.0
194
6
JAB97
NOMESCO Finland
Other laparoscopic repair of inguinal hernia
1705.4
164.5
159
*
JAF30
NOMESCO Finland
Repair of umbilical hernia using prosthetic material
197.9
147.7
153
8
5509B
ICD-9 Finland
Inguinal hernia, without mention of obstruction or gangrene[HERNIA INGUINALIS SINE GANGR/OBSTR,LATERALIS (SCROT]
+∞
121.4
116
*
K40.1
ICD-10 Finland
Bilateral inguinal hernia, with gangrene
+∞
111.9
107
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
106.1
1681
10211
5509A
ICD-9 Finland
Inguinal hernia, without mention of obstruction or gangrene[HERNIA INGUINALIS SINE GANGR/OBSTR,MEDIALIS]
+∞
100.4
96
*
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
6.1
95.0
167
281
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.2
87.1
839
4170
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.4
86.1
704
3262
N02BE01
ATC
paracetamol; systemic, rectal
2.3
81.5
3843
32508
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
122.3
78.2
84
7
K41.9
ICD-10 Finland
Unilateral or unspecified femoral hernia, without obstruction or gangrene
257.9
74.6
76
*
JAB93
NOMESCO Finland
Repair of recurrent inguinal hernia, implantation
+∞
73.1
70
*
JAB91
NOMESCO Finland
Repair of recurrent inguinal hernia, endoscopy
+∞
73.1
70
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
72.3
1628
10771
WX402
NOMESCO Finland
General anaesthesia
2.0
68.8
923
5155
D91
ICPC
Abdominal hernia other
11.0
61.7
66
61
K42.0
ICD-10 Finland
Umbilical hernia with obstruction, without gangrene
317.2
61.5
62
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
59.2
1310
8515
JAB00
NOMESCO Finland
Division and ligature of inguinal hernia sac
82.5
58.1
65
8
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
55.8
1156
7353
K43.0
ICD-10 Finland
Incisional hernia with obstruction, without gangrene
+∞
55.3
53
*
JA1AE, ,
SPAT
15.7
48.6
42
27
5509D
ICD-9 Finland
Inguinal hernia, without mention of obstruction or gangrene[HERNIA INGUINALIS SINE GANGR/OBSTR,RECIDIVANS]
+∞
48.0
46
*
G04CA02
ATC
tamsulosin; oral
1.6
48.0
1829
13518
N40
ICD-10 Finland
Hyperplasia of prostate
1.6
47.1
1731
12666
103
Kela drug reimbursment
Diabetes, insulin-treated
0.5
46.6
649
10774
ZXD20
NOMESCO Finland
Day surgery
2.1
44.8
485
2481
JAD11
NOMESCO Finland
Laparoscopic repair of incisional hernia
442.0
44.3
44
*
6124
FHL
Radical cutting and plastic with foreign material
72.4
44.0
50
7
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
41.0
2737
22623
WX320
NOMESCO Finland
Spinalanesthesy
1.6
38.1
983
6535
A10BA02
ATC
metformin; oral
0.6
37.6
731
11204
A98
ICPC
Health maint/preventive medicine
1.9
36.1
4056
37301
JAB96
NOMESCO Finland
Other repair of inguinal hernia
124.3
34.7
37
*
ZXE00
NOMESCO Finland
One hour or less
1.5
34.5
1474
10959
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.3
34.1
277
1262
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
33.3
3580
31974
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
33.2
903
6056
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.0
33.0
377
1958
ZXA00
NOMESCO Finland
Right side
1.6
32.9
1047
7284
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
31.6
1735
13507
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.6
31.4
916
6239
WX704
NOMESCO Finland
Intubation
2.0
30.9
342
1756
JAF11
NOMESCO Finland
Laparoscopic repair of umbilical hernia
315.0
30.9
31
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
30.4
1094
7804
215
Kela drug reimbursment
Diabetes, non-insulin-treated
0.6
29.0
609
9276
ZXA05
NOMESCO Finland
Left side
1.5
28.7
969
6802
ZXC86
NOMESCO Finland
Use of endoscopic device
6.9
28.0
43
63
XKD00
NOMESCO Finland
Uroflowmetry
1.5
27.9
1077
7776
J01MA02
ATC
ciprofloxacin; systemic
1.4
27.3
1702
13459
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
0.6
27.0
633
9419
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
26.6
694
4584
G04CA01
ATC
alfuzosin; oral
1.5
26.2
905
6367
A02BC02
ATC
pantoprazole; systemic
1.4
25.6
2670
22978
K42
ICD-10 Finland
Umbilical hernia
6.9
25.4
39
57
S18
ICPC
Laceration/cut
1.4
25.3
1880
15268
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.6
25.2
143
553
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.6
24.8
726
4918
N02AX02
ATC
tramadol; systemic, rectal
1.4
24.5
1747
14065
JAD10
NOMESCO Finland
Repair of incisional hernia
41.6
23.6
29
7
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
4.1
23.4
63
154
G04CB01
ATC
finasteride; oral
1.5
23.1
814
5735
Z2221
NOMESCO Finland
Medical doctor
1.5
22.9
977
7153
6125
FHL
Residual surgery, can be reported as a side effect
120.6
22.6
24
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
22.5
1995
16569
A10AE04
ATC
insulin glargine; parenteral
0.4
22.5
148
3251
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
22.3
586
3865
T90
ICPC
Diabetes non-insulin dependent
0.6
22.1
630
9045
K41.2
ICD-10 Finland
Bilateral femoral hernia, without obstruction or gangrene
+∞
21.9
21
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
21.8
1553
12432
A02BC05
ATC
esomeprazole; systemic
1.4
21.8
1412
11127
J01AA02
ATC
doxycycline; systemic
1.4
21.4
3017
26847
J01CA04
ATC
amoxicillin; systemic
1.4
21.4
3095
27658
R10.2
ICD-10 Finland
Pelvic and perineal pain
3.1
21.3
88
286
UJF32
NOMESCO Finland
Coloscopy
1.4
21.3
997
7418
JN2AE, ,
SPAT
5.9
20.9
37
63
A10AC01
ATC
insulin (human); parenteral
0.4
20.7
85
2284
K40.4
ICD-10 Finland
Unilateral or unspecified inguinal hernia, with gangrene
210.9
20.6
21
*
A10BB12
ATC
glimepiride; oral
0.4
20.3
103
2515
UKC02
NOMESCO Finland
Cystoscopy
1.5
20.1
853
6218
D01
ICPC
Abdominal pain/cramps general
1.8
20.0
318
1835
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
19.8
1094
8364
5509X
ICD-9 Finland
Inguinal hernia, without mention of obstruction or gangrene[HERNIA INGUINALIS SINE GANGR/OBSTR,ALIA SEU NUD]
+∞
19.8
19
*
J01DB01
ATC
cefalexin; oral
1.4
19.4
3287
29841
K43.2
ICD-10 Finland
Incisional hernia without obstruction or gangrene
46.2
19.2
23
5
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
19.0
653
4562
M79.6
ICD-10 Finland
Pain in limb
1.4
18.8
1368
10931
D06
ICPC
Abdominal pain localized other
1.9
18.6
237
1276
J01FA10
ATC
azithromycin; systemic
1.3
18.5
1787
14887
WX002
NOMESCO Finland
Sedation and analgesia
1.5
18.3
699
4986
JN2AE
NOMESCO Finland
Ultrasound examination of lower part of abdomen without contrast
3.6
17.8
57
158
B01AB05
ATC
enoxaparin; parenteral
1.4
17.8
1173
9212
K45.8
ICD-10 Finland
Other specified abdominal hernia without obstruction or gangrene
20.1
17.7
26
13
JAB40
NOMESCO Finland
Repair of inguinal hernia by laparotomy and reconstruction of abdominal wall
95.4
17.6
19
*
JN3AD
NOMESCO Finland
Abdominal CT examination
1.6
16.6
432
2835
R35
ICD-10 Finland
Polyuria
1.7
16.6
320
1950
XJH00
NOMESCO Finland
Transanal ultrasonography
1.6
16.5
391
2508
WX220
NOMESCO Finland
Ilioinguinal plexus blockade
20.1
16.4
24
12
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
16.0
864
6549
K44.0
ICD-10 Finland
Diaphragmatic hernia with obstruction, without gangrene
60.2
15.8
18
*
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
0.3
15.6
49
1500
JBB01
NOMESCO Finland
Laparoscopic repair of paraoesophageal hernia
160.5
15.5
16
*
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
0.4
15.4
84
1992
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
2.2
15.4
133
623
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
15.0
916
7076
I34.1
ICD-10 Finland
Mitral (valve) prolapse
2.2
14.9
128
598
R01AD09
ATC
mometasone; nasal
1.3
14.8
1359
11150
L82
ICD-10 Finland
Seborrhoeic keratosis
1.4
14.6
610
4415
R01AD12
ATC
fluticasone furoate; nasal
1.4
14.6
840
6428
M03BX02
ATC
tizanidine; oral
1.3
14.5
2099
18256
A02BC04
ATC
rabeprazole; oral
1.7
14.5
242
1416
M01AC06
ATC
meloxicam; systemic, rectal
1.3
14.4
1167
9403
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
0.6
14.3
231
3828
SPAT1153
SPAT
Removal of sutures
1.3
14.2
1216
9868
R51.80
ICD-10 Finland
Headache
1.6
14.0
386
2564
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
14.0
1825
15646
R03AC02
ATC
salbutamol; inhalant
1.3
14.0
1816
15561
R03DC03
ATC
montelukast; oral
1.5
14.0
427
2902
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
13.9
791
6032
A10BB01
ATC
glibenclamide; oral
0.3
13.9
45
1354
AA1AD
NOMESCO Finland
CT of head and brain
1.3
13.8
1106
8886
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
1.7
13.5
247
1483
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
13.5
497
3508
N41.1
ICD-10 Finland
Chronic prostatitis
2.0
13.5
152
787
J45
ICD-10 Finland
Asthma
1.6
13.3
279
1737
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.7
13.3
255
1552
KED22
NOMESCO Finland
Transurethral resection of prostate
1.5
13.3
373
2490
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
0.3
13.2
48
1365
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
13.2
247
1494
R01AD58
ATC
fluticasone, combinations; nasal
1.4
13.1
605
4451
WX290
NOMESCO Finland
Other blockage of nerve
1.3
13.1
1470
12343
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
13.0
1334
11069
R42
ICD-10 Finland
Dizziness and giddiness
1.4
13.0
765
5864
R52.9
ICD-10 Finland
Pain, unspecified
1.6
13.0
303
1938
M25.5
ICD-10 Finland
Pain in joint
1.3
12.9
923
7284
A10AB05
ATC
insulin aspart; parenteral
0.5
12.8
118
2304
N43.4
ICD-10 Finland
Spermatocele
2.1
12.8
119
575
R33
ICD-10 Finland
Retention of urine
1.5
12.6
449
3147
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.5
12.6
351
2337
JAC30
NOMESCO Finland
Repair of femoral hernia using prosthetic material
130.4
12.4
13
*
A10AE05
ATC
insulin detemir; parenteral
0.4
12.4
61
1511
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
12.3
571
4202
JAH01
NOMESCO Finland
Laparoscopy
2.1
12.3
108
510
A10BJ06
ATC
semaglutide; parenteral
0.3
12.2
37
1149
A02BC03
ATC
lansoprazole; oral
1.3
12.1
951
7603
H02AB04
ATC
methylprednisolone; systemic
1.5
12.0
444
3133
R4110
NOMESCO Finland
Physiotherapy
1.3
12.0
987
7934
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.5
12.0
367
2494
R55
ICD-10 Finland
Syncope and collapse
1.5
12.0
442
3120
L57.0
ICD-10 Finland
Actinic keratosis
1.5
11.8
418
2925
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.6
11.8
314
2069
J01FA06
ATC
roxithromycin; oral
1.3
11.7
1286
10733
N17
ICPC
Vertigo/dizziness
1.5
11.6
373
2562
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
11.5
949
7631
R06AX27
ATC
desloratadine; oral
1.4
11.5
705
5431
E11
ICD-10 Finland
Type 2 diabetes mellitus
0.7
11.4
394
5528
WX725
NOMESCO Finland
Noninvasive ventilation
1.7
11.3
195
1153
R53
ICD-10 Finland
Malaise and fatigue
1.3
11.3
752
5864
L02
ICPC
Back symptom/complaint
1.6
11.2
255
1621
WZC30
NOMESCO Finland
Teaching
1.4
11.2
586
4401
ZXE20
NOMESCO Finland
More than three and less than five hours
1.4
11.1
533
3945
JAC10
NOMESCO Finland
Repair of femoral hernia
43.4
10.9
13
*
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
10.9
823
6532
M01AE02
ATC
naproxen; oral, rectal
1.2
10.8
1880
16503
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
10.8
595
4503
R39.1
ICD-10 Finland
Other difficulties with micturition
1.8
10.8
154
862
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
10.8
659
5068
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
10.8
2446
22091
PHD99
NOMESCO Finland
Resection of other vein
1.8
10.7
145
799
M79.1
ICD-10 Finland
Myalgia
1.5
10.7
379
2653
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
10.7
846
6756
H02AB06
ATC
prednisolone; systemic
1.2
10.6
1763
15395
A02BC01
ATC
omeprazole; systemic
1.3
10.6
917
7413
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
10.5
261
1693
R63.4
ICD-10 Finland
Abnormal weight loss
1.8
10.5
143
789
55120
ICD-8 Finland
Other hernia of abdominal cavity without mention of obstruction, Hernia epigastrica
+∞
10.4
10
*
JAC11
NOMESCO Finland
Laparoscopic repair of femoral hernia
+∞
10.4
10
*
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.7
10.4
192
1158
SPAT1262
SPAT
Handing over of treatment supplies
0.7
10.4
459
6174
R03BA01
ATC
beclometasone; inhalant
1.4
10.4
419
3008
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.7
10.2
191
1155
K59.09
ICD-10 Finland
Constipation, unspecified
1.6
10.2
236
1506
TKE00
NOMESCO Finland
Needle biopsy of prostate
1.6
10.2
242
1554
M01AH05
ATC
etoricoxib; oral
1.2
10.2
2090
18631
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
10.2
1255
10585
G04BD12
ATC
mirabegron; oral
1.4
10.1
418
3013
H04.10
ICD-10 Finland
Dry eye syndrome
1.5
10.1
288
1929
K43
ICD-10 Finland
Ventral hernia
7.9
10.1
22
28
R12
ICD-10 Finland
Heartburn
1.6
10.1
213
1331
J01DA01
ATC
[U] cefalexin
1.2
10.0
2197
19705
N06AX11
ATC
mirtazapine; oral
1.3
10.0
1051
8694
J02AC01
ATC
fluconazole; systemic
1.3
10.0
772
6138
I73.0
ICD-10 Finland
Raynaud syndrome
2.6
9.9
54
207
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
1.7
9.7
161
942
G04CA52
ATC
tamsulosin and dutasteride; systemic
1.3
9.7
671
5249
H25.1
ICD-10 Finland
Senile nuclear cataract
1.3
9.7
1045
8665
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.4
9.7
472
3498
L12
ICPC
Hand/finger symptom/complaint
1.4
9.7
470
3482
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.2
9.7
1270
10777
S29
ICPC
Skin symptom/complaint other
1.3
9.7
621
4808
R20.2
ICD-10 Finland
Paraesthesia of skin
1.7
9.6
192
1182
R07.3
ICD-10 Finland
Other chest pain
1.5
9.6
331
2304
A10AA02, ,
ATC
0.3
9.6
19
743
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
1.4
9.5
550
4189
P07.3
ICD-10 Finland
Other preterm infants
15.0
9.5
15
10
D01BA02
ATC
terbinafine; oral
1.3
9.5
1016
8417
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.5
9.5
251
1654
R49.03
ICD-10 Finland
Atrophic dysphonia
2.6
9.5
52
200
M01AB05
ATC
diclofenac; systemic, rectal
1.2
9.5
2400
21792
N43.3
ICD-10 Finland
Hydrocele, unspecified
1.9
9.5
117
627
TQW40, ,
SPAT
1.6
9.5
247
1623
R05
ICD-10 Finland
Cough
1.3
9.4
654
5119
A10BH01
ATC
sitagliptin; oral
0.6
9.4
208
3202
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
2.1
9.4
83
394
55110
ICD-8 Finland
Other hernia of abdominal cavity without mention of obstruction, Umbilical
+∞
9.4
9
*
Z3226
NOMESCO Finland
Physiotherapist
1.3
9.3
612
4754
J01EA01
ATC
trimethoprim; systemic
1.3
9.3
578
4455
R21
ICPC
Throat symptom/complaint
1.4
9.3
450
3335
R31
ICD-10 Finland
Unspecified haematuria
1.4
9.2
524
3981
K50.9
ICD-10 Finland
Crohn disease, unspecified
2.7
9.2
48
180
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.5
9.1
281
1913
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
2.9
9.1
40
137
K46.9
ICD-10 Finland
Unspecified abdominal hernia without obstruction or gangrene
11.5
9.1
16
14
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
9.0
1500
13037
ZXH06, ,
SPAT
1.7
8.9
151
891
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.6
8.9
206
1318
H02AB07
ATC
prednisone; oral
1.4
8.9
426
3151
D03
ICPC
Heartburn
2.0
8.8
89
446
X58
ICD-10 Finland
Exposure to other specified factors
1.4
8.8
469
3530
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
2.4
8.7
58
245
M02AA07
ATC
piroxicam; topical
1.2
8.6
1191
10142
Z3231
NOMESCO Finland
Registered nurse
1.3
8.6
1008
8430
T81.9
ICD-10 Finland
Unspecified complication of procedure
2.3
8.5
59
254
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
8.5
2137
19303
D11
ICPC
Diarrhoea
1.5
8.5
274
1884
N01
ICPC
Headache
1.6
8.5
215
1405
L17
ICPC
Foot/toe symptom/complaint
1.3
8.5
926
7680
K41.3
ICD-10 Finland
Unilateral or unspecified femoral hernia, with obstruction, without gangrene
90.2
8.4
9
*
WX720
NOMESCO Finland
Own respiration
1.7
8.4
165
1014
K22.7
ICD-10 Finland
Barrett oesophagus
2.5
8.4
49
195
R03BA02
ATC
budesonide; inhalant
1.3
8.4
487
3713
B35.1
ICD-10 Finland
Tinea unguium
1.5
8.4
220
1449
J01FA09
ATC
clarithromycin; systemic
1.3
8.3
902
7469
F51.0
ICD-10 Finland
Nonorganic insomnia
1.4
8.3
361
2623
55121
ICD-8 Finland
Other hernia of abdominal cavity without mention of obstruction, Alia hernia ventralis (incisionalis, in cicactrice)
+∞
8.3
8
*
5530A
ICD-9 Finland
Other hernia of abdominal cavity without mention of obstruction or gangrene, Femoral hernia
+∞
8.3
8
*
U02
ICPC
Urinary frequency/urgency
1.4
8.3
312
2209
L08
ICPC
Shoulder symptom/complaint
1.3
8.2
693
5563
6129
FHL
Other measure in this category
14.5
8.2
13
9
XF404
NOMESCO Finland
Ambulatory ECG
1.4
8.2
339
2444
R74
ICPC
Upper respiratory infection acute
1.3
8.1
716
5780
Z71.8
ICD-10 Finland
Other specified counselling
1.3
8.1
905
7518
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
1.4
8.1
319
2279
Z02.4
ICD-10 Finland
Examination for driving licence
1.2
8.1
1388
12071
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.4
8.1
338
2441
UJH02
NOMESCO Finland
Anoscopy
1.8
8.1
116
653
A01
ICPC
Pain general/multiple sites
1.5
8.0
245
1666
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
1.5
8.0
214
1415
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.8
8.0
107
590
PHM76
NOMESCO Finland
Endovenous obliteration of v.saphena magna
1.9
8.0
91
476
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.5
7.9
274
1910
Z03.1
ICD-10 Finland
Observation for suspected malignant neoplasm
1.9
7.9
91
477
M54.5
ICD-10 Finland
Low back pain
1.2
7.9
1059
8975
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.4
7.9
366
2692
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.3
7.9
724
5877
R07.0
ICD-10 Finland
Pain in throat
1.7
7.8
152
931
L13
ICPC
Hip symptom/complaint
1.3
7.8
506
3919
ZXD05
NOMESCO Finland
Urgent procedure
1.2
7.8
1083
9210
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.4
7.8
300
2134
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
1.9
7.8
91
480
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.5
7.8
237
1612
A10AB01
ATC
insulin (human); parenteral
0.3
7.8
24
732
XF402
NOMESCO Finland
ECG with work load test
1.4
7.7
404
3029
H92.0
ICD-10 Finland
Otalgia
1.7
7.7
134
797
R13
ICD-10 Finland
Dysphagia
1.5
7.7
224
1508
J20
ICD-10 Finland
Acute bronchitis
1.4
7.7
283
1996
Z01.7
ICD-10 Finland
Laboratory examination
1.4
7.7
435
3301
C07AB07
ATC
bisoprolol; oral
1.2
7.7
2041
18462
2500A
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE,TYYPPI II]
0.2
7.7
14
573
J31.0
ICD-10 Finland
Chronic rhinitis
1.5
7.7
227
1534
N30.0
ICD-10 Finland
Acute cystitis
1.4
7.7
317
2286
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
7.6
801
6602
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.4
7.6
333
2425
XF400
NOMESCO Finland
ECG with 12 standard connections
1.3
7.6
614
4903
J05AB01
ATC
aciclovir; systemic
1.3
7.5
592
4707
R01AD05
ATC
budesonide; nasal
1.5
7.5
196
1289
A10BK03
ATC
empagliflozin; oral
0.7
7.5
212
3099
JN3AE, ,
SPAT
2.1
7.5
70
341
R03AK07
ATC
formoterol and budesonide; inhalant
1.3
7.5
585
4647
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
7.5
1371
11980
N02BF02
ATC
pregabalin; oral
1.6
7.5
161
1013
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.3
7.5
605
4831
P20
ICPC
Memory disturbance
1.3
7.4
519
4061
A10BB07
ATC
glipizide; oral
0.2
7.4
6
334
H3603, E113,
ICD-10 Finland
0.0
7.4
*
216
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
2.3
7.4
52
226
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.4
7.4
303
2182
R05
ICPC
Cough
1.3
7.4
687
5583
5531A
ICD-9 Finland
Other hernia of abdominal cavity without mention of obstruction or gangrene, Umbilical hernia
+∞
7.3
7
*
JAB95
NOMESCO Finland
Operation of inguinal hernia, removal of mesh due to complication
+∞
7.3
7
*
5509C
ICD-9 Finland
Inguinal hernia, without mention of obstruction or gangrene[HERNIA INGUINALIS SINE GANGR/OBSTR,COMBINATA]
+∞
7.3
7
*
JAB90
NOMESCO Finland
Repair of recurrent inguinal hernia, suture
+∞
7.3
7
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.3
7.2
499
3898
R06AE07
ATC
cetirizine; oral
1.2
7.2
1198
10360
R52.2
ICD-10 Finland
Other chronic pain
1.8
7.2
96
529
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.4
7.2
295
2125
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
1.8
7.2
106
603
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.5
7.2
212
1434
K30
ICD-10 Finland
Functional dyspepsia
1.4
7.1
268
1899
N41.0
ICD-10 Finland
Acute prostatitis
1.7
7.1
113
656
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
1.9
7.1
83
438
WX702
NOMESCO Finland
Supraglottic ventilation device
1.6
7.1
150
939
R60.0
ICD-10 Finland
Localized oedema
1.3
7.1
407
3094
R23.3
ICD-10 Finland
Spontaneous ecchymoses
2.1
7.1
61
288
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
0.4
7.1
44
983
H93.1
ICD-10 Finland
Tinnitus
1.5
7.1
219
1495
Z01.2
ICD-10 Finland
Dental examination
1.2
7.1
1328
11619
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.5
7.1
228
1570
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
2.2
7.1
59
276
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.4
7.0
352
2624
M20.1
ICD-10 Finland
Hallux valgus (acquired)
1.6
7.0
146
914
A10BG03
ATC
pioglitazone; oral
0.3
6.9
22
660
A98
ICD-10 Finland
Other viral haemorrhagic fevers, not elsewhere classified
2.1
6.9
59
278
J02AC02
ATC
itraconazole; systemic
1.3
6.9
475
3711
M05BA04
ATC
alendronic acid; oral
1.5
6.9
177
1162
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
2.7
6.9
36
136
TPH07
NOMESCO Finland
Cathetrisation of artery
1.3
6.8
438
3386
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
1.6
6.8
145
910
KF8AE, ,
SPAT
2.8
6.8
32
114
I47.1
ICD-10 Finland
Supraventricular tachycardia
1.7
6.8
128
781
R04.0
ICD-10 Finland
Epistaxis
1.4
6.7
293
2132
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.7
6.7
120
721
J31.1
ICD-10 Finland
Chronic nasopharyngitis
3.1
6.7
26
83
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.3
6.7
412
3168
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
0.5
6.7
58
1149
J33.0
ICD-10 Finland
Polyp of nasal cavity
1.7
6.7
118
707
KMAK, ,
NOMESCO Finland
1.2
6.7
1587
14167
N06AX21
ATC
duloxetine; oral
1.4
6.7
280
2026
A01AB09
ATC
miconazole; local oral
1.5
6.6
219
1515
J01MA06
ATC
norfloxacin; oral
1.4
6.6
312
2301
N81.6
ICD-10 Finland
Rectocele
2.1
6.6
57
270
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
0.4
6.6
34
818
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
1.7
6.6
124
755
K59.0
ICD-10 Finland
Constipation
1.5
6.6
172
1133
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
6.6
1820
16448
NF1AA
NOMESCO Finland
Hip X-ray examination
1.4
6.6
287
2090
M54.6
ICD-10 Finland
Pain in thoracic spine
1.5
6.6
167
1094
C05AA08
ATC
fluocortolone; rectal, topical
1.3
6.6
418
3229
D12
ICPC
Constipation
1.7
6.6
117
703
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.6
6.5
164
1071
M54.4
ICD-10 Finland
Lumbago with sciatica
1.3
6.5
481
3791
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.4
6.5
233
1637
R01AD08
ATC
fluticasone; nasal
1.2
6.5
785
6565
R03BB04
ATC
tiotropium bromide; inhalant
1.3
6.5
402
3093
A03FA02
ATC
cisapride; oral, rectal
1.5
6.5
199
1357
R15
ICD-10 Finland
Faecal incontinence
2.1
6.5
55
259
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
1.7
6.5
113
675
P07.2
ICD-10 Finland
Extreme immaturity
70.0
6.4
7
*
M54.2
ICD-10 Finland
Cervicalgia
1.5
6.4
206
1418
N03AX12
ATC
[U] gabapentin; oral
1.3
6.4
488
3865
S82
ICPC
Naevus/mole
1.3
6.4
374
2855
205
Kela drug reimbursment
Chronic hypertension
0.8
6.3
907
10572
R03AC03
ATC
terbutaline; inhalant
1.4
6.3
345
2604
H13
ICPC
Plugged feeling ear
1.2
6.3
729
6065
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
1.8
6.3
94
537
N81.1
ICD-10 Finland
Cystocele
2.1
6.3
55
262
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.5
6.3
187
1267
JAE10
NOMESCO Finland
Repair of epigastric hernia
+∞
6.2
6
*
L95
ICPC
Osteoporosis
2.0
6.2
60
297
JFB00
NOMESCO Finland
Partial resection of small intestine
2.1
6.2
52
244
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.2
6.2
1053
9111
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
1.5
6.2
171
1143
KH1CD
NOMESCO Finland
Very extensive urinary tract ultrasound examination
2.2
6.1
48
219
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
6.1
1349
11941
M19.8
ICD-10 Finland
Other specified arthrosis
1.7
6.1
102
602
R06AE09
ATC
levocetirizine; oral
1.4
6.1
327
2463
N03AX16
ATC
[U] pregabalin
1.2
6.1
728
6082
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
2.3
6.1
45
201
D07AC01
ATC
betamethasone; topical
1.2
6.0
1236
10872

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
2238
16044
1.79
77.12
2.6
2.8
—
—
—
0
0
2737
22263
1.59
47.22
4.8
4.3
112.36
1011.15
e6/l
1.93
56
425
2971
25217
1.53
37.54
4.6
4.1
—
—
—
0
0
3976
36296
1.86
36.80
21.4
19.4
4.01
4.02
mmol/l
1.61
3893
35317
3968
36201
1.86
36.79
21.2
19.3
139.63
139.64
mmol/l
0.16
3888
35272
3909
35539
1.80
36.16
16.7
15.4
—
—
—
0
0
4125
38178
2.04
35.72
26.2
23.4
6.77
6.98
e9/l
6.28
4019
36931
1483
10987
1.52
35.54
2.6
2.7
—
—
—
0
0
4122
38154
2.03
35.47
26.2
23.5
230.28
234.14
e9/l
3.56
4030
37052
4122
38171
2.03
35.16
26.1
23.4
91.71
91.47
fl
2.93
4070
37520
4122
38174
2.02
35.10
26.2
23.4
4.52
4.54
e12/l
1.47
4010
36934
4121
38167
2.02
35.00
26.1
23.3
30.65
30.57
pg
2.25
4071
37518
4122
38180
2.02
34.99
26.4
23.6
137.66
137.93
g/l
0.50
4072
37526
4119
38143
2.02
34.98
26.5
23.6
40.77
40.89
%
0.24
3832
35339
3811
34508
1.71
34.37
18.0
16.2
28.24
28.10
mg/l
0.08
3108
27951
3323
29176
1.54
33.46
21.3
19.1
14.89
15.33
%
1.68
3276
28605
2804
23798
1.48
33.08
4.6
4.1
—
—
—
0
0
1180
8451
1.54
32.51
2.5
2.6
—
—
—
0
0
2883
24736
1.47
31.13
5.2
5.1
2.65
3.30
ug/l
2.20
2588
22172
2373
19685
1.44
30.28
4.6
4.4
22.31
22.10
%
0.29
1238
10001
3218
28372
1.48
28.93
23.2
20.5
333.74
333.77
g/l
0.07
3190
28126
2041
16627
1.42
27.89
3.8
3.5
0.00
0.00
estimate
2.35
380
3535
1234
9218
1.47
26.75
4.4
4.2
83.30
83.49
%
0.10
1207
9029
3094
27244
1.44
26.56
8.3
7.9
76.01
80.90
u/l
7.75
2919
25721
1677
13288
1.42
26.33
3.5
3.2
5.71
5.75
ph
0.25
114
778
2018
16538
1.40
25.97
4.9
4.6
0.00
0.00
estimate
0.50
360
3356
3966
36854
1.67
25.66
11.7
10.8
26.71
28.59
u/l
1.49
3834
35397
1347
10298
1.44
25.62
3.7
3.3
—
—
—
0
0
1048
7644
1.48
25.43
3.9
3.4
—
—
—
0
0
2036
16760
1.39
25.27
3.8
3.5
0.00
0.00
estimate
0.69
348
3139
1657
13171
1.41
25.26
4.3
3.9
60.54
96.34
e6/l
2.16
1240
9970
2000
16428
1.39
25.08
7.1
6.6
1.20
1.20
mmol/l
0.17
1855
14987
2579
22126
1.39
24.75
5.4
5.1
6.54
7.02
mmol/l
30.98
2444
20869
2358
19998
1.38
23.88
9.1
9.2
4.20
4.40
e9/l
3.72
2029
17350
3330
29975
1.43
23.35
4.2
3.9
1.97
2.17
mu/l
1.47
3018
26884
2848
25110
1.37
21.45
4.2
3.9
11.21
13.05
mm/h
8.27
2633
23060
1494
11914
1.38
21.39
3.8
3.4
87.56
96.26
e6/l
0.15
1169
9422
3654
33644
1.47
21.20
4.8
4.9
5.91
6.18
mmol/l
37.29
3332
30318
1899
15766
1.36
20.94
5.5
5.3
35.09
34.83
g/l
1.16
1786
14657
907
6647
1.46
20.92
3.2
3.0
0.73
0.96
e6/l
1.90
505
3990
1618
13142
1.36
20.40
3.1
2.8
166.30
192.54
ug/l
1.62
1483
12012
1717
14117
1.35
19.85
3.1
3.1
0.75
0.80
ug/l
0.92
1201
9742
1328
10499
1.38
19.68
4.4
4.3
7.40
7.40
ph
0.25
217
2176
1587
12905
1.36
19.67
2.2
2.2
—
—
—
0
0
2198
18777
1.34
19.51
6.7
6.7
12.36
12.96
umol/l
1.83
2093
17890
3752
34873
1.47
19.33
5.2
5.2
2.59
2.56
mmol/l
0.85
3452
31902
1077
8306
1.39
18.33
2.8
2.7
2.72
3.36
e6/l
2.19
971
7487
1352
10830
1.36
18.12
3.7
3.3
0.26
0.45
e6/l
6.01
1042
8485
2616
23050
1.33
18.09
3.5
3.2
15.00
14.91
pmol/l
0.97
2342
20564
844
6257
1.43
17.99
3.4
3.2
0.98
1.01
e6/l
0.05
446
3624
2115
18101
1.32
17.93
7.9
7.5
1.21
1.20
mmol/l
0.57
1818
15303
1097
8514
1.38
17.90
7.4
7.0
—
—
—
0
0
469
3096
1.58
17.61
2.6
2.5
41.25
54.92
u/l
0.38
416
2669
841
6285
1.42
17.04
3.3
3.3
2.43
2.45
mmol/l
5.00
748
5512
2045
17536
1.31
16.61
6.3
5.9
0.04
0.04
e9/l
1.91
1752
15064
2084
17946
1.30
16.28
6.3
5.9
1.82
1.95
e9/l
1.77
1818
15726
2036
17491
1.30
16.14
6.3
5.8
0.61
0.64
e9/l
5.24
1743
15023
943
7253
1.38
16.01
4.3
3.8
1.01
1.02
kg/l
0.49
114
1082
977
7563
1.37
15.93
4.2
4.0
583.18
745.51
ng/l
0.41
841
6433
455
3052
1.55
15.87
3.5
3.3
—
—
—
0
0
1493
12320
1.32
15.84
2.3
2.1
78.41
76.20
nmol/l
2.21
1327
10898
2092
18076
1.30
15.71
6.5
6.1
0.20
0.21
e9/l
1.45
1820
15701
1922
16464
1.29
15.27
6.9
6.6
—
—
—
0
0
1376
11288
1.32
15.05
3.7
3.5
2.33
2.34
mmol/l
2.15
1229
9883
586
4186
1.46
15.03
1.3
1.2
—
—
—
0
0
3648
34101
1.38
14.93
4.6
4.7
4.37
4.36
mmol/l
0.25
3359
31400
753
5654
1.40
14.63
1.2
1.2
1.27
2.27
u/ml
2.45
190
1469
2189
19178
1.28
14.15
20.7
18.0
1.37
1.36
inr
0.19
544
5594
3615
33835
1.36
13.94
4.5
4.7
1.36
1.32
mmol/l
6.99
3301
30918
1754
15005
1.28
13.55
2.1
2.0
92.37
91.77
pmol/l
0.21
955
8552
447
3118
1.48
12.88
2.5
2.4
108.61
175.42
ug/g
7.40
350
2498
1394
11643
1.29
12.87
2.3
2.2
243.06
255.46
u/l
0.16
1321
10894
1137
9261
1.31
12.68
4.3
3.8
0.00
0.00
estimate
1.54
344
3062
1140
9303
1.30
12.51
3.0
3.1
—
—
—
0
0
3491
32706
1.31
11.93
5.6
6.5
38.98
41.20
mmol/mol
51.33
3222
30055
1840
16039
1.25
11.53
6.6
6.2
0.66
0.64
%
0.46
1716
14979
3494
32803
1.30
11.31
4.1
4.2
1.22
1.34
mmol/l
21.88
3175
29753
1138
9447
1.27
10.64
1.3
1.3
—
—
—
0
0
1881
16549
1.24
10.51
6.5
6.2
2.86
2.90
%
0.36
1754
15456
693
5391
1.34
10.50
1.4
1.5
2.57
2.76
g/l
1.56
399
3373
908
7338
1.30
10.46
1.8
1.8
1181.31
1141.80
nmol/l
0.53
680
5521
1119
9290
1.27
10.42
2.3
2.2
2.96
2.99
mg/l
0.16
951
7880
1888
16646
1.23
10.25
6.7
6.5
9.17
8.98
%
1.54
1759
15578
1891
16693
1.23
10.10
6.4
6.0
58.39
58.36
%
0.03
1768
15640
1317
11186
1.25
10.03
2.8
2.6
63.08
68.03
u/l
0.28
1228
10384
1058
8759
1.27
10.02
1.6
1.6
20.00
19.38
nmol/l
0.47
927
7492
1920
17007
1.23
9.83
6.6
6.3
26.16
26.14
%
0.03
1799
15941
882
7156
1.29
9.79
1.8
1.8
1.23
1.37
mg/l
0.66
681
5619
973
7993
1.28
9.79
3.0
3.0
573.60
576.05
mosm/kgh2o
0.13
822
6912
521
3923
1.37
9.73
3.0
2.9
7.94
10.13
umol/l
2.17
463
3488
632
4932
1.33
9.31
2.5
2.5
1.66
1.76
%
1.40
551
4363
488
3666
1.37
9.24
7.2
7.3
1.32
1.44
mmol/l
1.42
469
3556
475
3565
1.37
9.04
8.6
8.6
—
—
—
0
0
289
1985
1.49
8.99
1.2
1.1
—
—
—
0
0
346
2479
1.43
8.64
1.5
1.4
—
—
—
0
0
532
4095
1.34
8.58
1.5
1.5
—
—
—
0
0
2416
22163
1.20
7.86
3.1
3.2
49.80
59.35
u/l
6.85
2262
20411
490
3778
1.33
7.80
1.3
1.4
—
—
—
0
0
1665
14818
1.20
7.46
4.2
3.9
36.70
77.26
ng/l
2.63
1214
11408
1738
15545
1.19
7.33
11.4
10.6
0.00
0.00
e9/l
0.27
1412
12773
256
1795
1.45
7.22
2.5
2.4
—
—
—
0
0
759
6257
1.26
7.20
2.8
2.6
12.68
12.85
umol/l
0.27
721
5843
619
4979
1.28
7.20
7.0
7.4
12.14
11.89
kpa
0.53
583
4725
619
4981
1.28
7.18
7.1
7.4
5.06
5.08
kpa
0.20
583
4732
618
4978
1.28
7.11
7.0
7.4
0.89
1.01
mmol/l
0.33
490
3860
517
4078
1.30
6.99
7.8
8.3
123.04
123.05
g/l
0.00
504
3943
1319
11585
1.20
6.66
4.7
4.6
—
—
—
0
0
167
1095
1.55
6.55
11.9
10.7
—
—
—
0
0
709
5876
1.25
6.37
2.8
2.6
2.24
2.25
g/l
0.29
657
5468
128
797
1.62
6.27
1.2
1.2
—
—
—
0
0
565
4572
1.27
6.24
1.4
1.4
—
—
—
0
0
673
5575
1.24
6.06
3.0
2.7
22.90
22.76
%
0.09
574
4756
560
4543
1.27
6.05
7.4
7.7
95.47
95.17
%
0.44
543
4348
276
2029
1.38
6.00
4.3
4.2
23.92
23.94
mmol/l
0.05
265
1979
304
2271
1.36
5.99
9.6
9.7
24.20
24.23
mmol/l
0.06
282
2195
406
3169
1.31
5.93
1.5
1.5
—
—
—
0
0
70
1256
0.55
5.90
2.0
2.2
88.96
146.42
ug/min
0.88
44
747
159
1060
1.52
5.82
3.0
3.5
—
—
—
0
0
314
2370
1.35
5.80
9.9
10.2
—
—
—
0
0
482
3868
1.28
5.70
2.3
2.4
8.24
8.51
ug/l
0.07
430
3427
243
1765
1.40
5.69
1.2
1.2
—
—
—
0
0
776
6580
1.22
5.57
2.2
2.1
30.11
30.27
s
0.31
747
6383
1197
13466
0.85
5.48
3.6
4.0
9.70
11.59
mg/mmol
0.50
770
9199
1269
11265
1.18
5.46
3.1
3.3
39.90
37.45
u/l
0.17
1202
10649
466
3795
1.25
4.88
3.1
2.6
65.81
69.23
e9/l
1.14
343
2935
190
1373
1.40
4.65
3.6
3.7
4.45
4.43
pmol/l
0.09
170
1226
527
4376
1.23
4.63
1.8
1.7
—
—
—
0
0
328
2580
1.29
4.57
9.7
7.7
24.58
24.66
mmol/l
0.17
328
2556
1335
12052
1.15
4.46
3.1
3.2
1657.63
1670.55
ng/l
0.04
1160
10487
191
1393
1.39
4.44
3.8
3.8
303.31
1747.88
u/ml
1.00
162
1210
123
832
1.49
4.30
1.2
1.2
—
—
—
0
0
165
1182
1.41
4.27
1.6
1.6
—
—
—
0
0
1149
12739
0.87
4.09
3.2
3.4
291.33
299.61
mg/l
0.02
757
8854
556
4706
1.21
4.04
1.3
1.2
38.18
42.29
iu/ml
0.26
172
1424
266
2079
1.30
3.93
2.8
2.9
—
—
—
0
0
516
4379
1.20
3.65
1.8
1.8
—
—
—
0
0
128
904
1.43
3.64
2.8
3.0
—
—
—
0
0
538
4596
1.19
3.55
2.0
2.2
14.09
12.78
nmol/l
3.27
479
4080
191
1449
1.33
3.53
1.9
1.8
—
—
—
0
0
261
2069
1.28
3.49
1.5
1.7
1.44
1.55
g/l
1.06
219
1779
1015
9138
1.14
3.40
1.6
1.7
1.24
1.40
mmol/l
8.76
854
7517
134
969
1.39
3.36
1.3
1.2
3.23
0.59
u/ml
0.79
18
82
1003
9047
1.14
3.26
3.3
3.3
—
—
—
0
0
133
970
1.38
3.19
1.4
1.5
291.17
248.51
ug/g
0.37
79
614
214
1680
1.29
3.12
4.8
5.0
—
—
—
0
0
416
3516
1.20
3.10
2.4
2.3
0.21
0.20
g/l
0.55
380
3274
87
592
1.48
3.06
1.4
1.3
69.37
65.56
mmol/l
0.35
70
474
306
2513
1.23
3.05
4.9
4.5
93.06
102.93
ng/l
1.07
276
2205
507
4382
1.18
2.94
1.2
1.2
10.89
14.54
u/ml
0.59
186
1606
71
469
1.52
2.90
1.4
1.4
17.64
18.83
iu/l
0.14
59
378
471
4057
1.18
2.85
4.0
4.1
1.65
1.85
mmol/l
0.53
398
3371
20
414
0.48
2.83
2.1
2.2
747.87
652.24
ml
0.62
15
260
64
417
1.54
2.79
1.1
1.1
—
—
—
0
0
334
2795
1.21
2.79
5.9
7.0
24.58
24.41
mmol/l
0.38
321
2642
88
615
1.44
2.74
1.4
1.4
99.35
116.47
u/ml
0.68
17
129
233
1883
1.25
2.72
1.4
1.3
—
—
—
0
0
225
1816
1.25
2.66
1.3
1.3
75.29
64.93
au/ml
0.19
14
97
246
2006
1.24
2.65
2.4
2.4
18.21
18.78
au/ml
0.03
21
117
188
1486
1.28
2.65
1.6
1.5
—
—
—
0
0
614
5434
1.15
2.63
7.1
6.4
1.02
1.04
mmol/l
1.01
572
5091
48
297
1.62
2.61
1.9
2.4
11.82
11.43
%
0.24
48
297
1216
13126
0.90
2.59
3.2
3.4
8.26
8.25
mmol/l
0.03
1040
10946
194
1545
1.27
2.58
1.3
1.2
—
—
—
0
0
62
410
1.52
2.56
1.3
1.4
190.05
192.44
pmol/l
0.03
62
410
85
600
1.42
2.53
1.5
1.2
283.35
299.04
u/ml
0.19
52
376
67
974
0.68
2.51
4.3
3.5
7.67
7.82
mmol/l
0.17
67
950
82
1149
0.71
2.50
4.0
4.0
—
—
—
0
0
115
857
1.35
2.49
1.5
1.2
—
—
—
0
0
89
636
1.41
2.48
1.6
1.3
—
—
—
0
0
629
5602
1.14
2.46
2.1
2.1
—
—
—
0
0
126
954
1.33
2.46
1.8
1.6
—
—
—
0
0
411
3552
1.17
2.42
2.5
2.6
66.04
66.28
g/l
0.25
366
3239
22
110
2.00
2.40
4.2
4.6
—
—
—
0
0
467
4080
1.16
2.39
4.1
4.0
5.89
5.83
kpa
0.66
448
3959
27
146
1.85
2.36
29.1
35.8
6.06
7.23
ug/l
2.72
21
134
421
3657
1.17
2.33
3.0
3.0
262.26
225.49
ng/l
0.38
388
3359
38
229
1.66
2.32
3.6
4.1
—
—
—
0
0
10
34
2.95
2.28
1.0
1.1
—
—
—
0
0
353
3032
1.18
2.26
3.9
4.7
—
—
—
0
0
37
592
0.62
2.22
3.4
2.4
105.38
105.69
mmol/l
0.15
37
583
37
592
0.62
2.22
3.4
2.4
4.16
4.13
mmol/l
0.21
37
583
707
6389
1.13
2.21
3.7
3.5
0.82
0.81
mmol/l
0.62
664
6007
477
4202
1.15
2.20
8.2
7.4
10.39
10.87
mmol/l
0.66
454
3988
37
226
1.64
2.17
2.1
2.6
42.19
36.34
%
0.72
16
122
79
569
1.40
2.15
1.3
1.3
—
—
—
0
0
383
3327
1.17
2.14
3.7
3.4
4.40
4.57
kpa
0.93
366
3212
37
583
0.63
2.10
3.4
2.4
—
—
—
0
0
20
102
1.96
2.10
1.2
1.3
169.42
153.00
nmol/l
0.13
12
77
93
692
1.35
2.09
1.4
1.4
—
—
—
0
0
5
10
5.00
2.07
5.0
5.5
332.40
336.80
umol/l
—
5
10
87
642
1.36
2.06
1.1
1.1
0.85
10.97
u/ml
—
8
66
125
974
1.29
2.04
2.2
2.3
131.39
130.44
g/l
0.15
95
712
31
185
1.68
2.00
1.2
1.4
1.41
1.46
g/l
0.56
31
185
19
97
1.96
2.00
1.1
1.0
—
—
—
0
0
55
377
1.46
1.98
3.4
3.6
—
—
—
0
0
78
570
1.37
1.98
1.3
1.2
—
—
—
0
0
45
296
1.53
1.97
1.2
1.2
—
—
—
0
0
191
1573
1.22
1.96
2.5
2.4
432.97
604.26
ug/l
0.60
180
1500
64
891
0.71
1.95
1.2
1.5
0.76
0.87
nmol/l
0.82
49
744
143
1141
1.26
1.95
1.7
1.9
211.23
205.27
pmol/l
0.30
132
1066
201
1665
1.22
1.95
1.2
1.3
—
—
—
0
0
34
210
1.62
1.94
1.1
1.3
—
—
—
0
0
1144
10678
1.10
1.93
3.0
3.0
3974.80
5770.54
umol/l
0.82
1008
9330
37
234
1.59
1.92
1.6
2.4
413.81
505.22
e6/l
0.66
32
195
46
306
1.51
1.92
2.3
2.3
—
—
—
0
0
159
1291
1.24
1.87
2.1
2.2
21.75
21.94
s
0.19
141
1163
230
1941
1.19
1.85
3.2
2.7
0.62
0.65
%
0.73
230
1929
142
1141
1.25
1.84
4.8
3.4
1.69
1.68
mg/l
0.02
134
1042
209
1754
1.20
1.79
2.1
1.5
25.06
17.47
u/ml
—
5
50
66
478
1.39
1.79
1.7
1.5
—
—
—
0
0
24
138
1.74
1.79
3.1
2.2
—
—
—
0
0
379
3340
1.15
1.78
1.7
1.6
—
—
—
0
0
14
67
2.09
1.75
1.1
1.3
—
—
—
0
0
127
1014
1.26
1.75
4.7
7.0
104.86
105.28
mmol/l
0.55
116
892
127
1014
1.26
1.75
4.7
7.0
11.47
11.48
mmol/l
0.01
116
892
117
926
1.27
1.74
1.5
1.6
10171.06
20138.23
e6/l
2.83
90
667
118
935
1.27
1.74
2.1
1.8
10.94
11.49
mg/l
0.37
110
870
35
225
1.56
1.73
1.2
1.2
35.19
36.24
mmol/l
0.07
28
197
20
110
1.82
1.72
1.1
1.0
—
—
—
0
0
343
3011
1.15
1.71
4.1
3.9
—
—
—
0
0
45
307
1.47
1.70
1.8
2.1
35.53
35.60
%
0.01
45
300
15
75
2.00
1.69
1.3
1.1
—
—
—
0
0
20
111
1.81
1.68
1.2
1.1
—
—
—
0
0
35
228
1.54
1.64
1.6
1.8
—
—
—
0
0
153
1258
1.22
1.64
3.0
2.2
37.32
37.56
g/l
0.19
132
1091
170
1413
1.21
1.64
4.5
6.1
1.19
1.41
mmol/l
3.64
152
1230
109
864
1.27
1.62
2.3
2.4
—
—
—
0
0
82
626
1.32
1.62
1.7
1.5
1267.55
2264.21
e6/l
1.42
58
448
181
1516
1.20
1.62
2.8
2.3
10.43
10.36
g/l
0.06
159
1344
176
1472
1.20
1.60
1.5
1.6
—
—
—
0
0
64
472
1.36
1.59
1.6
1.8
4.61
4.94
mmol/24h
0.32
59
414
102
805
1.27
1.58
3.5
2.9
0.80
0.83
nmol/l
0.29
85
616
18
99
1.82
1.57
1.1
1.1
—
—
—
0
0
323
2844
1.15
1.57
2.8
2.4
375.56
372.43
nmol/l
0.11
300
2637
131
1066
1.24
1.56
2.8
2.7
3.05
3.70
g/l
7.56
124
1021
399
3564
1.13
1.56
1.6
1.5
—
—
—
0
0
120
969
1.24
1.54
1.3
1.5
1.12
1.17
g/l
0.95
114
924
450
4053
1.12
1.54
1.3
1.3
512.89
454.67
titre
0.24
90
780
22
130
1.70
1.52
2.1
1.9
18.16
83.29
ug/l
0.56
22
117
51
366
1.40
1.50
1.1
1.1
—
—
—
0
0
51
366
1.40
1.50
1.1
1.1
—
—
—
0
0
35
234
1.50
1.49
2.9
2.6
—
—
—
0
0
9
38
2.37
1.45
3.6
7.1
78.32
1554.36
g/mol
—
9
30
72
550
1.31
1.45
1.5
1.6
3.94
4.41
iu/l
0.22
17
163
92
728
1.27
1.42
1.6
1.5
—
—
—
0
0
261
2282
1.15
1.42
3.0
3.3
4.62
5.94
e9/l
1.57
199
1770
198
1695
1.18
1.42
1.3
1.3
222.57
340.04
u/ml
1.34
184
1550
68
885
0.76
1.41
4.3
3.5
57.87
1097.58
u/ml
2.38
63
820
125
1026
1.22
1.40
4.0
4.1
—
—
—
0
0
332
2954
1.13
1.40
2.4
2.3
—
—
—
0
0
131
1081
1.22
1.40
1.3
1.4
—
—
—
0
0
107
865
1.24
1.39
1.7
1.6
—
—
—
0
0
92
731
1.26
1.38
1.6
1.5
33.95
32.20
g/l
0.69
79
643
183
2136
0.85
1.37
8.8
4.1
—
—
—
0
0
51
376
1.36
1.32
1.2
1.3
130681.69
151753.02
e6/l
0.10
35
261
113
927
1.22
1.30
1.3
1.4
0.23
0.24
g/l
0.88
108
880
72
560
1.29
1.30
1.4
1.4
—
—
—
0
0
5
18
2.78
1.28
1.4
1.7
1.47
1.37
umol/l
—
5
18
372
3360
1.12
1.25
1.5
1.5
—
—
—
0
0
8
36
2.22
1.24
1.3
1.5
57.00
43.61
umol/l
—
8
36
156
1327
1.18
1.24
1.2
1.2
213.47
125.82
iu/ml
1.08
52
445
13
70
1.86
1.23
1.1
1.1
—
—
—
0
0
5
19
2.63
1.21
1.0
1.4
1.46
1.35
%
—
5
19
176
1517
1.17
1.20
2.9
2.3
2.88
2.92
g/l
0.20
155
1353
17
101
1.69
1.19
1.4
1.4
27.69
24.20
g/l
0.48
17
82
18
109
1.65
1.18
1.1
1.0
—
—
—
0
0
17
102
1.67
1.16
1.4
1.2
38.82
30.43
%
0.39
11
63
20
126
1.59
1.14
1.3
1.4
—
—
—
0
0
16
257
0.62
1.10
2.6
1.9
30.33
213.71
ug/min
—
9
68
83
674
1.24
1.09
1.2
1.2
2.94
6.89
u/ml
—
10
63
5
21
2.38
1.09
1.0
1.3
—
—
—
0
0
29
410
0.71
1.08
1.4
1.3
0.60
0.21
nmol/l
—
7
35
36
261
1.38
1.07
1.4
1.5
—
—
—
0
0
23
153
1.51
1.06
2.5
2.5
—
—
—
0
0
53
409
1.30
1.06
1.3
1.3
—
—
—
0
0
5
22
2.27
1.03
6.6
8.5
—
—
—
0
0
87
716
1.22
1.02
1.8
1.7
305.58
272.84
mu/l
0.43
81
674
13
75
1.74
1.02
1.5
1.4
—
—
—
0
0
26
370
0.70
1.02
1.4
1.3
—
—
nmol/l
—
0
0
83
680
1.22
1.02
1.3
1.5
—
—
—
0
0
40
298
1.35
1.02
1.6
1.6
—
—
—
0
0
188
1657
1.14
0.99
1.2
1.2
—
—
—
0
0
114
968
1.18
0.98
1.5
1.7
—
—
—
0
0
87
721
1.21
0.97
1.2
1.2
26.13
35.10
u/ml
—
7
30
47
362
1.30
0.97
2.4
2.0
512.00
1081.74
titre
—
5
23
161
1837
0.87
0.96
9.9
4.3
24.66
24.64
mmol/l
0.03
152
1699
18
116
1.55
0.96
1.1
1.1
—
—
—
0
0
71
577
1.23
0.95
1.6
1.5
35821.86
73693.75
e6/l
0.94
44
347
420
3880
1.09
0.95
4.5
4.3
6.44
25.89
ug/l
4.41
341
3303
239
2146
1.12
0.94
1.5
1.4
—
—
—
0
0
185
1635
1.14
0.94
2.8
2.2
7.10
7.35
g/l
1.27
164
1469
184
1627
1.14
0.93
2.8
2.2
3.77
3.74
g/l
0.11
162
1466
18
117
1.54
0.93
1.1
1.3
57.77
65.88
%
0.53
18
98
38
286
1.33
0.92
1.0
1.1
—
—
—
0
0
82
680
1.21
0.92
1.2
1.2
2.89
6.87
u/ml
1.10
16
95
28
201
1.40
0.91
1.2
1.2
—
—
—
0
0
70
572
1.23
0.91
1.7
1.5
—
—
—
0
0
22
151
1.46
0.90
2.1
1.6
—
—
—
0
0
163
1436
1.14
0.89
3.5
3.3
35.02
44.13
mg/l
1.29
137
1122
18
119
1.51
0.88
5.7
7.1
—
—
—
0
0
113
970
1.17
0.87
2.7
2.7
16.18
16.14
%
0.03
68
514
47
369
1.28
0.86
1.2
1.2
—
—
—
0
0
163
1440
1.14
0.86
3.5
3.3
54.16
67.01
mg/l
0.78
135
1127
10
57
1.76
0.83
1.7
1.2
9.01
8.90
mg/l
—
10
51
6
32
1.88
0.81
1.0
1.1
—
—
—
0
0
28
206
1.36
0.81
1.0
1.0
—
—
—
0
0
46
364
1.27
0.81
1.2
1.2
—
—
—
0
0
46
364
1.27
0.81
1.3
1.4
277.77
283.17
mosm/kgh2o
0.71
35
284
77
645
1.20
0.80
3.3
2.3
—
—
—
0
0
6
33
1.82
0.79
2.2
3.0
—
—
—
0
0
173
1933
0.89
0.79
1.8
2.0
3.46
2.29
ug/l
0.27
153
1714
32
242
1.32
0.78
1.0
1.1
2.66
4.13
u/ml
0.50
14
95
81
685
1.19
0.77
2.7
2.6
—
—
—
0
0
28
371
0.75
0.76
1.3
1.3
—
—
—
0
0
61
503
1.22
0.76
1.6
1.4
6.57
6.32
mmol/l
0.20
55
454
59
485
1.22
0.76
2.1
2.2
—
—
—
0
0
55
449
1.23
0.75
1.1
1.1
—
—
—
0
0
332
3076
1.09
0.74
1.4
1.4
—
—
—
0
0
7
38
1.84
0.73
2.3
1.4
—
—
—
0
0
5
25
2.00
0.72
1.2
1.1
—
—
—
0
0
6
107
0.56
0.72
1.2
1.1
—
—
—
0
0
65
544
1.20
0.71
1.5
1.6
0.82
0.91
g/l
0.35
48
422
9
58
1.55
0.69
1.0
1.1
—
—
—
0
0
9
58
1.55
0.69
15.7
11.0
5.00
6.17
mmol/l
—
9
58
157
1408
1.12
0.69
3.5
3.3
2.05
4.64
ratio
—
7
110
17
118
1.44
0.69
1.5
2.0
—
—
—
0
0
244
2241
1.09
0.68
3.1
2.7
—
—
—
0
0
7
120
0.58
0.67
1.3
1.4
—
—
—
0
0
64
539
1.19
0.67
1.0
1.1
—
—
—
0
0
58
484
1.20
0.66
3.4
3.3
—
—
—
0
0
16
111
1.44
0.65
4.4
2.5
1.87
1.10
ug/l
0.66
16
103
428
4542
0.94
0.65
4.7
4.8
32.71
31.99
%
0.66
305
3144
39
313
1.25
0.64
1.1
1.1
1.83
2.80
u/ml
0.90
14
133
57
477
1.20
0.64
1.1
1.2
24.19
39.38
u/ml
—
8
31
41
332
1.24
0.63
1.2
1.3
7.34
6.67
g/l
0.52
27
233
41
332
1.24
0.63
1.2
1.3
0.56
0.42
g/l
0.49
28
234
103
907
1.14
0.62
1.3
1.4
5.86
6.96
u/l
0.98
86
736
41
333
1.23
0.62
1.2
1.3
3.19
3.00
g/l
0.25
27
235
288
2679
1.08
0.62
2.4
2.7
10.63
10.72
g/l
0.10
253
2445
154
1393
1.11
0.61
3.9
3.4
0.26
0.35
g/l
1.51
78
696
33
262
1.26
0.60
1.0
1.1
1.50
2.56
u/ml
0.79
14
124
32
401
0.80
0.60
2.9
3.1
58.15
70.89
mg/l
0.11
25
315
276
2965
0.93
0.60
7.3
3.9
5.15
5.12
kpa
0.27
263
2803
115
1024
1.13
0.60
3.8
4.8
2.41
2.50
mmol/l
0.15
77
678
20
148
1.35
0.59
8.7
6.9
—
—
—
0
0
296
3169
0.93
0.59
4.4
4.4
1.21
1.22
mmol/l
0.28
271
2796
12
81
1.48
0.57
1.6
1.6
—
—
—
0
0
227
2101
1.08
0.56
1.6
1.9
1.20
1.35
g/l
0.29
201
1899
29
229
1.27
0.56
1.0
1.1
—
—
—
0
0
13
184
0.71
0.56
1.2
1.3
—
—
—
0
0
181
1970
0.92
0.55
3.3
3.5
—
—
—
0
0
6
38
1.58
0.54
1.7
1.1
—
—
—
0
0
12
82
1.46
0.54
1.2
1.4
—
—
—
0
0
42
503
0.83
0.54
2.6
2.7
—
—
—
0
0
281
3000
0.93
0.54
4.2
4.0
0.53
0.73
%
1.54
95
1081
26
204
1.28
0.54
7.3
5.4
35.80
51.06
u/ml
—
8
59
65
563
1.16
0.52
1.8
1.6
—
—
—
0
0
25
196
1.28
0.52
1.8
1.5
7.42
7.54
u/l
0.02
18
165
12
168
0.71
0.50
1.1
1.0
—
—
—
0
0
69
603
1.15
0.50
4.1
4.0
—
—
—
0
0
6
41
1.46
0.50
2.5
1.3
—
—
—
0
0
275
2926
0.94
0.49
7.3
3.9
7.43
7.41
ph
1.67
50
361
64
558
1.15
0.48
2.2
2.6
0.85
1.61
g/24h
3.01
27
300
16
119
1.35
0.48
1.1
1.2
—
—
—
0
0
66
751
0.88
0.47
4.5
3.4
1.13
1.56
%
0.93
57
662
53
457
1.16
0.47
1.3
1.2
6.59
4.50
u/ml
0.51
27
218
27
218
1.24
0.46
1.0
1.1
—
—
—
0
0
88
788
1.12
0.45
1.2
1.1
—
—
—
0
0
38
321
1.19
0.43
1.0
1.1
3.22
1.49
u/ml
0.39
14
163
39
331
1.18
0.42
1.2
1.3
—
—
—
0
0
5
32
1.56
0.42
1.2
1.5
—
—
—
0
0
80
717
1.12
0.42
2.4
2.4
—
—
—
0
0
26
212
1.23
0.42
1.6
1.4
72.26
67.78
%
0.30
19
177
6
95
0.63
0.42
1.3
1.9
—
—
—
0
0
24
194
1.24
0.41
1.0
1.1
—
—
—
0
0
127
1167
1.09
0.41
3.7
4.7
7.42
7.42
ph
0.50
121
1050
13
96
1.36
0.41
6.3
7.4
—
—
—
0
0
5
33
1.52
0.41
1.6
1.3
113.82
178.35
mmol/l
—
5
26
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
18
141
1.28
0.40
2.0
1.8
—
—
—
0
0
0
18
0.00
0.40
0.0
2.2
—
4.36
—
0
18
5
35
1.43
0.39
1.4
1.1
1.50
1.90
umol/24h
—
5
35
5
35
1.43
0.39
1.6
1.6
—
—
—
0
0
80
722
1.11
0.38
1.3
1.4
17.95
13.27
e6/l
0.21
61
559
80
722
1.11
0.38
1.4
1.4
1570.86
938.50
e6/l
0.18
66
588
28
334
0.84
0.38
1.3
1.2
—
—
—
0
0
9
67
1.34
0.38
3.3
6.3
82.33
58.24
u/l
—
9
67
26
311
0.83
0.37
1.8
1.9
1.22
0.93
u/field
—
9
115
15
191
0.78
0.36
1.1
1.2
—
—
—
0
0
9
70
1.29
0.36
1.1
1.1
17.88
15.95
umol/l
—
9
64
9
71
1.27
0.36
1.4
2.1
6.36
8.32
mg/l
—
9
57
84
764
1.10
0.36
2.3
2.0
—
—
—
0
0
43
375
1.15
0.35
1.1
1.2
—
—
—
0
0
5
76
0.66
0.35
1.4
1.3
12.72
18.31
pmol/l
—
5
63
5
76
0.66
0.35
1.2
1.3
0.86
0.71
mmol/l
—
5
53
5
77
0.65
0.35
1.0
1.2
—
128.45
—
0
11
6
42
1.43
0.35
1.2
1.1
—
—
—
0
0
6
42
1.43
0.35
3.0
2.0
—
—
—
0
0
6
42
1.43
0.35
1.0
1.1
—
—
—
0
0
15
117
1.28
0.35
1.5
1.8
—
—
—
0
0
10
73
1.37
0.34
1.6
1.7
—
—
—
0
0
6
44
1.36
0.34
1.8
2.5
2.84
2.82
mmol/l
—
6
38
57
509
1.12
0.34
1.2
1.3
150.50
208.61
miu/ml
0.88
19
172
11
82
1.34
0.34
3.0
2.1
—
—
—
0
0
84
767
1.10
0.34
2.4
2.3
—
—
—
0
0
349
3636
0.96
0.34
4.6
4.6
—
—
—
0
0
83
758
1.10
0.33
2.3
2.3
—
—
—
0
0
19
232
0.82
0.33
1.6
2.1
—
—
—
0
0
25
210
1.19
0.32
1.0
1.0
0.05
0.34
u/ml
—
5
63
7
53
1.32
0.30
1.1
1.0
—
—
—
0
0
72
657
1.10
0.30
1.2
1.3
—
—
—
0
0
18
147
1.23
0.30
1.6
3.2
—
—
—
0
0
96
889
1.08
0.30
2.9
2.9
—
—
—
0
0
11
84
1.31
0.30
1.0
1.1
—
—
—
0
0
65
591
1.10
0.30
2.6
2.4
—
—
—
0
0
84
911
0.92
0.30
1.4
1.2
81.25
148.49
titre
—
8
86
11
141
0.78
0.29
1.4
1.9
—
—
—
0
0
18
148
1.22
0.29
1.3
1.1
16.32
10.82
iu/ml
—
6
33
200
1905
1.05
0.28
4.1
5.2
1.70
1.66
%
0.28
188
1766
20
237
0.84
0.27
1.5
1.3
—
—
—
0
0
301
3125
0.96
0.27
4.2
4.2
0.11
0.11
%
0.02
97
1093
16
131
1.22
0.27
1.1
1.0
—
—
—
0
0
8
65
1.23
0.27
1.0
1.1
—
—
—
0
0
52
471
1.11
0.26
1.3
1.3
—
—
—
0
0
11
86
1.28
0.26
1.0
1.1
—
—
—
0
0
11
86
1.28
0.26
1.0
1.1
—
—
—
0
0
11
86
1.28
0.26
1.0
1.1
—
—
—
0
0
14
171
0.82
0.26
1.6
1.5
—
—
—
0
0
318
3293
0.96
0.25
4.2
4.1
0.83
1.00
%
0.76
112
1255
90
965
0.93
0.25
2.2
2.5
31.37
34.68
umol/l
0.90
76
866
11
138
0.80
0.25
1.7
1.9
330.17
98.65
umol/l
—
6
75
81
752
1.08
0.25
1.4
2.2
—
—
—
0
0
22
188
1.17
0.25
1.0
1.1
—
—
—
0
0
45
406
1.11
0.25
1.0
1.1
0.86
2.55
u/ml
1.91
17
210
60
550
1.09
0.25
3.6
4.8
309.41
357.95
umol/l
1.95
54
477
35
311
1.13
0.25
1.1
1.2
3.78
31.68
u/ml
—
5
13
9
77
1.17
0.24
2.6
3.2
—
—
—
0
0
11
87
1.26
0.24
2.1
1.7
—
—
—
0
0
18
152
1.18
0.23
1.9
1.2
159.52
192.90
mmol/24h
1.17
18
152
62
572
1.09
0.23
2.0
2.0
89.53
88.94
%
0.24
62
567
5
39
1.28
0.23
3.0
2.7
0.00
0.18
u/field
—
5
39
7
92
0.76
0.22
1.1
1.2
—
—
—
0
0
196
1882
1.04
0.22
4.1
5.2
0.90
0.87
%
0.38
184
1745
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.22
—
0
10
0
10
0.00
0.21
0.0
1.0
—
0.02
—
0
5
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
0.49
—
0
11
0
11
0.00
0.21
0.0
1.3
—
2.19
—
0
11
0
12
0.00
0.21
0.0
1.0
—
803.33
—
0
12
27
239
1.13
0.21
3.1
2.8
—
—
—
0
0
248
2396
1.04
0.21
1.4
1.4
—
—
—
0
0
11
89
1.24
0.20
1.1
1.0
—
—
—
0
0
22
192
1.15
0.20
1.2
1.4
3.89
2.95
u/ml
0.12
15
116
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
29
259
1.12
0.20
1.7
1.7
92.28
95.40
umol/l
0.21
29
259
60
558
1.08
0.19
1.1
1.1
—
—
—
0
0
21
239
0.88
0.19
2.8
2.2
—
—
—
0
0
11
133
0.83
0.19
1.0
1.2
—
0.09
g/l
—
0
9
10
122
0.82
0.19
1.7
3.3
—
—
—
0
0
10
122
0.82
0.19
1.0
1.1
1159.80
1522.30
miu/ml
—
10
122
1142
11563
0.98
0.19
3.0
3.2
—
—
—
0
0
16
137
1.17
0.18
1.4
1.2
—
—
—
0
0
37
405
0.91
0.18
1.4
1.2
1.14
1.45
nmol/l
1.55
30
356
287
2952
0.97
0.18
4.3
4.1
0.34
0.32
%
0.02
80
924
88
833
1.06
0.18
1.2
1.3
599.41
535.97
mg/l
0.42
83
779
7
59
1.19
0.18
1.4
1.4
—
—
—
0
0
7
61
1.15
0.17
1.4
1.5
47.44
71.48
%
—
7
46
810
7982
1.02
0.17
1.7
1.8
26140250.08
28817312.92
pmol/l
0.05
658
6576
57
533
1.07
0.17
6.1
20.7
7.48
7.60
mmol/l
0.07
45
442
10
119
0.84
0.15
1.1
1.2
—
—
—
0
0
14
121
1.16
0.15
1.3
1.3
—
—
—
0
0
35
323
1.08
0.14
1.4
1.4
—
—
—
0
0
9
83
1.08
0.14
1.0
1.5
—
—
—
0
0
105
1007
1.04
0.14
1.1
1.1
—
—
—
0
0
38
353
1.08
0.14
1.1
1.1
0.14
1.07
u/ml
1.94
13
151
21
189
1.11
0.13
1.7
1.5
1.94
2.03
%
0.02
15
164
17
151
1.13
0.13
2.5
1.7
560.08
954.47
e6/l
0.76
12
108
28
257
1.09
0.13
1.2
1.8
—
—
—
0
0
26
283
0.92
0.12
2.8
2.6
7.42
7.42
ph
0.09
15
103
39
365
1.07
0.12
1.0
1.1
6.43
6.15
u/ml
0.03
17
181
1107
11165
0.99
0.12
4.6
4.3
—
—
—
0
0
24
261
0.92
0.11
1.4
1.3
—
—
—
0
0
31
289
1.07
0.11
1.0
1.0
267.35
307.86
ng/l
0.48
20
194
31
290
1.07
0.10
1.0
1.0
590.53
704.04
ng/l
0.61
19
187
68
653
1.04
0.10
1.5
1.3
—
—
—
0
0
5
44
1.14
0.10
1.0
1.4
—
—
—
0
0
5
44
1.14
0.10
1.0
1.4
—
—
—
0
0
5
44
1.14
0.10
1.0
1.4
—
—
—
0
0
25
269
0.93
0.10
1.2
1.2
—
29.91
—
0
11
5
46
1.09
0.09
1.2
1.3
—
—
—
0
0
123
1263
0.97
0.09
1.1
1.0
—
—
—
0
0
12
107
1.12
0.08
1.3
1.3
—
—
—
0
0
5
62
0.81
0.08
1.0
1.1
—
—
—
0
0
47
450
1.04
0.08
1.2
1.6
—
—
—
0
0
17
184
0.92
0.07
1.1
1.4
3.06
3.66
mmol/l
0.45
17
167
7
80
0.87
0.07
1.6
1.4
—
—
—
0
0
9
86
1.05
0.07
2.7
1.7
—
—
—
0
0
48
462
1.04
0.07
2.6
2.2
42.10
26.69
mg/l
—
10
123
72
701
1.03
0.06
1.8
1.8
20.30
22.13
ug/l
0.26
72
686
12
131
0.92
0.05
1.2
1.2
—
—
—
0
0
33
316
1.04
0.05
1.2
1.1
—
—
—
0
0
83
848
0.98
0.05
3.1
3.6
28.86
32.40
mg/l
0.42
59
560
214
2165
0.99
0.05
3.5
3.7
25.27
25.00
mmol/l
0.53
205
2097
51
496
1.03
0.04
1.5
1.6
63.67
65.15
%
0.11
36
323
58
566
1.02
0.04
3.3
2.8
4.50
320.98
u/ml
2.81
58
556
75
763
0.98
0.03
1.2
1.3
90.86
36.15
u/l
0.54
69
662
31
320
0.97
0.03
2.5
2.3
14768.84
4014.25
u/l
—
6
107
21
201
1.04
0.03
1.6
1.7
2.87
3.26
u/field
0.08
15
146
13
122
1.07
0.02
1.8
1.5
—
—
—
0
0
32
311
1.03
0.02
1.2
1.2
370.11
334.84
nmol/l
0.49
27
240
61
619
0.99
0.02
1.1
1.1
78.13
317.80
iu/ml
0.44
12
126
73
738
0.99
0.01
3.7
2.3
—
—
—
0
0
111
1118
0.99
0.01
3.5
3.5
—
—
—
0
0
73
737
0.99
0.01
1.2
1.3
3.58
3.98
mmol/l
5.29
67
684
35
353
0.99
0.00
3.8
2.9
—
—
—
0
0
37
375
0.99
0.00
1.3
1.5
28.03
23.70
%
0.41
30
241
22
223
0.99
0.00
2.7
10.9
—
—
—
0
0
31
305
1.02
0.00
1.5
1.2
68.00
148.75
titre
—
5
48
12
115
1.04
0.00
1.2
1.3
—
—
—
0
0
45
453
0.99
0.00
1.1
1.2
—
—
—
0
0
31
310
1.00
0.00
1.6
1.3
—
—
—
0
0
10
100
1.00
0.00
1.6
2.4
6.87
8.65
mmol/l
—
10
57
12
118
1.02
0.00
1.8
1.4
—
—
—
0
0
12
118
1.02
0.00
1.8
1.4
—
—
—
0
0
14
139
1.01
0.00
1.7
1.9
—
—
—
0
0
10
101
0.99
0.00
1.3
1.4
9.88
9.77
ug/l
—
10
101
19
185
1.03
0.00
3.2
5.7
51.71
70.90
mg/l
1.16
14
134
47
470
1.00
0.00
5.2
4.2
—
—
—
0
0
45
451
1.00
0.00
4.9
3.5
60.45
57.03
%
0.56
38
380
13
134
0.97
0.00
2.0
1.5
5065.25
6088.00
e6/l
—
8
75
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
-0.00
2.4
3.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
35.47
—
0
7
6
64
0.94
-0.00
2.2
1.7
132.17
168.32
ng/l
—
6
64
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
58
0.86
-0.00
4.8
6.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.4
—
34.81
—
0
8

Mortality – FinRegistry

Association

Association between endpoint HERING_BILATERAL and mortality.

Females

Parameter HR [95% CI] p-value
HERING_BILATERAL 1.146 [1.01, 1.3] 0.038
Birth year 0.993 [0.98, 1.0] 0.095

During the follow-up period (1.1.1998 — 31.12.2019), 657 out of 3063 females with HERING_BILATERAL died.

Males

Parameter HR [95% CI] p-value
HERING_BILATERAL 0.986 [0.91, 1.07] 0.741
Birth year 0.988 [0.98, 1.0] 0.009

During the follow-up period (1.1.1998 — 31.12.2019), 5117 out of 25068 males with HERING_BILATERAL died.

Mortality risk

Mortality risk for people of age

years, who have HERING_BILATERAL.

N-year risk Females Males
1 0.08% 0.224%
5 0.647% 1.255%
10 1.526% 3.107%
15 2.9% 5.815%
20 5.48% 9.394%

Relationships between endpoints

Index endpoint: HERING_BILATERAL – Inguinal hernia, bilateral

GWS hits: 9

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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